CN210720161U

CN210720161U - TIP head detection frame, sample type detection module assembly and immunoassay analyzer

Info

Publication number: CN210720161U
Application number: CN201921005008.1U
Authority: CN
Inventors: 袁凯; 王颖; 郭绪智; 刘欢; 席再军; 方建伟
Original assignee: Wuhan Easydiagnosis Biomedicine Co ltd
Current assignee: Wuhan Easydiagnosis Biomedicine Co ltd
Priority date: 2019-06-28
Filing date: 2019-06-28
Publication date: 2020-06-09
Anticipated expiration: 2029-06-28

Abstract

The utility model provides a first frame of surveying of TIP, including surveying framework, baffle and positioning mechanism, it sets up a cavity to survey the framework, the cavity has relative first lateral wall and the second lateral wall that sets up, be formed with at least one on the first lateral wall and go into the unthreaded hole, correspond on the second lateral wall at least one income unthreaded hole becomes to have at least one light outlet, it is formed with at least one light trap to correspond on the baffle, the baffle passes through positioning mechanism detachably install in the cavity, so that at least one the light trap is located correspondingly go into the unthreaded hole and corresponding go out on the central axis of unthreaded hole. The technical problem that in the prior art, after a detection frame body and a partition plate are integrally formed or welded, hole positions on the partition plate and the detection frame body are prone to dislocation, and therefore a measurement result is inaccurate is solved; meanwhile, the utility model also provides a sample type detection module subassembly and immunoassay appearance.

Description

TIP head detection frame, sample type detection module assembly and immunoassay analyzer

Technical Field

The utility model relates to a sample type detects the field, concretely relates to first frame, sample type detection module subassembly and chemiluminescence immunoassay appearance of surveying of TIP.

Background

The light beam emitted by a transmitting end required for sample type detection reaches a receiving end after passing through a partition plate positioned in a TIP head detection frame, the partition plate is formed by bending after being integrally formed with a detection frame body in the prior art, or is formed by welding after being bent by adopting a metal plate.

SUMMERY OF THE UTILITY MODEL

The utility model provides a TIP head detection frame, which solves the technical problem that the hole sites on the partition board and the detection frame body are easy to be misplaced to cause inaccurate measurement result after the detection frame body and the partition board are integrally formed or welded and formed in the prior art; and simultaneously, the utility model also provides a module subassembly that the chemiluminescent sample type that has above-mentioned TIP head to survey the frame detects.

The utility model provides a scheme as follows of above-mentioned technical problem: the utility model provides a TIP head detection frame, includes detection framework, baffle and positioning mechanism, a cavity is seted up to the detection framework, the cavity has relative first lateral wall and the second lateral wall that sets up, be formed with at least one on the first lateral wall and go into the unthreaded hole, correspond on the second lateral wall at least one goes into the unthreaded hole and is formed with at least one coaxial light-emitting hole, it is formed with at least one light trap to correspond on the baffle, the baffle passes through positioning mechanism detachably install in the cavity, so that at least one the light trap is located correspondingly go into the unthreaded hole and corresponding on the central axis of light-emitting hole.

The utility model provides a TIP head detection frame, wherein baffle and detection framework can be dismantled and be connected, install the baffle in the cavity through positioning mechanism, ensure that the light trap is located corresponding the center axis of income unthreaded hole and corresponding the light-emitting hole, can effectively avoid the hole site on the baffle and the hole site on the detection framework to take place the problem of dislocation; the adoption has the sample type detection module subassembly of above-mentioned TIP head detection frame, can solve because of the hole site dislocation leads to measuring the technical problem that misaligns, the utility model also provides a chemiluminescence immunoassay appearance that has above-mentioned sample type detection module subassembly.

The above description is only an overview of the technical solution of the present invention, and in order to make the technical means of the present invention clearer and can be implemented according to the content of the description, the following detailed description is made with reference to the preferred embodiments of the present invention and accompanying drawings. The detailed description of the present invention is given by the following examples and the accompanying drawings.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention without undue limitation to the invention. In the drawings:

fig. 1 is an exploded schematic view of a TIP head detection frame according to embodiment 1 of the present invention;

FIG. 2 is a schematic diagram of an exploded view of a TIP head probe box at another angle relative to FIG. 1;

fig. 3 is a schematic perspective view of a chemiluminescent sample type detection module assembly according to embodiment 2 of the present invention;

fig. 4 is an exploded view of a chemiluminescent sample type detection module assembly according to embodiment 2 of the present invention;

FIG. 5 is an exploded view of a chemiluminescent sample type detection module assembly shown at another angle relative to FIG. 4;

fig. 6 is a schematic perspective view of a chemiluminescent immunoassay analyzer provided in embodiment 3 of the present invention.

Detailed Description

The principles and features of the present invention are described below in conjunction with the following drawings, the examples given are only intended to illustrate the present invention and are not intended to limit the scope of the present invention. The invention is described in more detail in the following paragraphs by way of example with reference to the accompanying drawings. The advantages and features of the present invention will become more fully apparent from the following description and appended claims. It should be noted that the drawings are in simplified form and are not to precise scale, and are provided for convenience and clarity in order to facilitate the description of the embodiments of the present invention.

Example 1

As shown in fig. 1 and fig. 2, the present invention provides a TIP detection frame 10, which includes a detection frame 11, a partition 12 and a positioning mechanism, wherein the detection frame 11 has a cavity 11a, the cavity 11a has an opening 11b, a first side wall 111 and a second side wall 112 opposite to each other, and a third side wall 113 and a fourth side wall 114 opposite to each other, at least one light incident hole 111a is formed on the first side wall 111, at least one coaxial light emitting hole 112a is formed on the second side wall 112 corresponding to the at least one light incident hole 111a, that is, the light incident hole 111a and the corresponding central axis O1 of the light emitting hole 112a are on a straight line. At least one light hole 12a is correspondingly formed on the partition 12, and the partition 12 is detachably mounted on the first side wall 111 and the second side wall 112 in the cavity 11a through a positioning mechanism, so that at least one light hole 12a is located on the central axis of the corresponding light inlet hole 111a and light outlet hole 112 a.

In this embodiment, the number of the light holes, the light inlet holes and the light outlet holes is set to six, wherein the light hole 12a is a rectangular hole, and the light inlet hole 111a and the light outlet hole 112a are circular holes, it can be understood that the shapes of the light hole 12a, the light inlet hole 111a and the light outlet hole 112a can be set according to the requirement, for example, the light hole 12a is a long and narrow elliptical hole, and the light inlet hole 111a and the light outlet hole 112a are square holes.

The central symmetry axis O2 of the light hole 12a in the length direction intersects with the central axis O1 of the light inlet 111a and the light outlet 112a, i.e. the central symmetry axis O2 of the light hole 12a in the length direction cannot be staggered with the line connecting the central axes O1 of the light inlet 111a and the light outlet 112 a. Preferably, the central symmetry axis O2 of the light-transmitting hole 12a perpendicularly intersects the central axis O1. In the present embodiment, the central axis O3 of the light-transmitting hole 12a, the axis of the corresponding light-entering hole 111a, and the central axis of the corresponding light-exiting hole 112a are located on the same straight line.

In order to ensure that the partition 12 is installed in the cavity 11a without deflection, the third sidewall 113 and the fourth sidewall 114 of the detecting frame 11 are correspondingly provided with a locking slot 113a and a locking slot 114a, respectively, and two ends of the partition 12 are detachably inserted into the

locking slots

113a and 114a, respectively, to be fixed.

It is understood that, in order to facilitate the installation of the partition 12, the upper and lower ends of the

slots

113a, 114a penetrate through the probe housing, so that the partition 12 can be inserted from the upper end or the lower end of the

slots

113a, 114a when the partition 12 is installed. In this embodiment, the

slots

113a and 114a are formed by wire cutting. It is understood that the

slots

113a, 114a may also be opened to a proper position so that the partition 12 is inserted into the

slots

113a, 114a and then fixed, so that the light inlet 111a is located on the central axis of the corresponding light-transmitting hole 12a and the corresponding light outlet 112 a.

Specifically, the positioning mechanism includes at least one positioning pin 131 and a fastener 132, mounting holes are correspondingly formed in the first side wall 111, the second side wall 112 and the partition 12, and the positioning pin 131 sequentially penetrates through the mounting holes of the first side wall 111 and the second side wall 112 of the partition 12 and is matched and fixed with the positioning pin 131 on the outer side surface of the first side wall 111 or the second side wall 112 through the fastener 132. As a preferred embodiment of the present invention, a screw thread is provided at the end of the positioning pin 131, the fastening member 132 is a screw, the threaded end of the positioning pin 131 extends out of the outer side 111b of the first side wall 111 after the positioning pin 131 sequentially passes through the positioning holes of the first side wall 111, the partition 12 and the second side wall 112, and the screw is used for screwing the end of the positioning pin 131 to fix the positioning pin 131.

It can be understood that the number of the positioning pins can be determined according to actual conditions, in this embodiment, the positioning pins are arranged in two, and the positioning holes formed in the partition plate 12 are symmetrically arranged, so that the position stability of the partition plate 12 after installation can be more facilitated.

The following describes the installation process of the TIP header detection block in this embodiment:

after the partition board 12 is inserted from the upper end or the lower end of the

locking slots

113a, 114a, the positioning pin 131 is inserted along the positioning hole on the first side wall 111, passes through the positioning hole of the partition board 12, and then extends out of the corresponding positioning hole on the second side wall 112, and then the two ends of the positioning pin 131 are fixed by the screw 132, i.e. the assembly is successful.

Through the cooperation of the positioning pin 131, the

slots

113a, 114a and the fastener 132, the partition 12 is detachably disposed in the cavity 11a and is respectively fixedly connected to the first sidewall 111 and the second sidewall 112, and meanwhile, the central axes of the light inlet 111a, the light transmitting hole 12a and the light outlet 112a are ensured to be located on the same straight line, so that the problem of dislocation of the hole site on the partition 12 and the hole site on the detection frame 11 can be effectively avoided.

Example 2

As shown in fig. 3 to 5 in combination with fig. 2, this embodiment discloses a sample type detection module assembly 100 having the TIP head probe block 10, further including a TIP slot 20, a transmitting plate 30, and a receiving plate 40. Wherein the TIP slot 20 is installed at the opening 11 b.

The transmitting plate 30 has a transmitting surface 31, the receiving plate 40 has a receiving surface 41, the transmitting plate 30 is mounted on the outer side of the first sidewall 111, the outer side surface of the first sidewall 111 is opposite to the transmitting surface 31, the receiving plate 40 is mounted on the outer side of the second sidewall 112, and the outer side surface of the second sidewall 112 is opposite to the receiving surface 41.

At least one light emitting end 32 is installed on the emitting surface 31, the receiving surface 41 is provided with a light receiving end 42 corresponding to the light emitting end 32 one by one for receiving the light emitted by the light emitting end 32, a group of corresponding light emitting ends 32 and light receiving ends 42 respectively correspond to a group of corresponding light inlet holes 111a and light outlet holes 112a, a central axis connecting line of the light inlet holes 111a and the corresponding light outlet holes 112a is overlapped with the light path of the corresponding light emitting end 32 and the corresponding light receiving end 42, a TIP placing hole 20a is formed on the TIP slot 20, and the central line of the TIP placing hole 20a is vertically intersected with the light path connecting line of the corresponding light emitting end 32 and the corresponding light receiving end 42.

Wherein, TIP groove 20 includes the installation department 21 that is located its both ends and the portion of placing 22 between both ends, and TIP placing hole 20a is located portion of placing 22 and is used for placing the TIP head that is used for splendid attire detection sample, and installation department 21 cooperatees with cavity 11a, and is concrete, and the outside profile and the opening 11b looks adaptation of the lower extreme of this portion of placing 22, and the lower extreme of placing 22 stretches into cavity 11a through opening 11 b.

It can be understood that the mounting portion 21 is fixed to the upper ends of the third and

fourth sidewalls

113 and 114 by the pin 150, and then fixed to the screw hole 160a by the screw 160, or fixed by other methods, so as to ensure that the TIP placement hole is stable after the TIP slot is mounted.

A first gap is left between the outer side surface of the first side wall 111 and the emitting surface 31, and a second gap is left between the outer side surface of the second side wall 112 and the receiving surface 42. In this embodiment, the preset method of the first gap and the second gap includes: at least one first mounting pillar 1111 with the height equal to the size of the first gap is arranged on the outer side surface of the first side wall 111, one end of the first mounting pillar 1111 is fixedly connected with the outer side surface of the first side wall 111, and the transmitting plate 30 is mounted at the other end of the first mounting pillar 1111; the outer side surface of the second side wall 112 has at least one second mounting pillar 1121 with a height equal to the size of the second gap, one end of the second mounting pillar 1121 is fixedly connected to the outer side surface of the second side wall 112, and the receiving plate 40 is mounted at the other end of the second mounting pillar 1121.

When the heights of the first mounting post 1111 and the second mounting post 1121 are set, it is ensured that when the assembled chemiluminescent sample type detecting module assembly 100 is placed in the tip slot at the empty tip head, the light value received by the light receiving end 42 by the light of the light emitting end 32 passing through the empty tip head satisfies the preset light value, it can be understood that the preset light value is related to the luminous intensity of the light emitting end 32 and the material of the tip head, and the preset light value is set by itself according to the actual test requirement. In order to ensure the accuracy of experimental data in practical application, the size range of the first gap is 6.5mm-7.5mm, and the size range of the second gap is 2.5mm-3.5 mm.

In this embodiment, in order to ensure the installation stability of the transmitting plate, the number of the first installation columns 1111 is three, and the three first installation columns are not located on a straight line, so that the transmitting plate can be completely fixed according to the principle that three points form a plane; similarly, in order to ensure the installation stability of the receiving plate, the number of the second installation columns 1121 is three, and the three second installation columns 1121 are not located on a straight line.

In addition, in order to ensure that the position of the light receiving end 42 corresponds to the preset position when the receiving board is installed, at least two second positioning posts 1122 are installed on the outer side surface of the second side wall 112, and second positioning holes 40b matched with the second positioning posts 1122 are formed on the receiving board 40.

The following describes the installation and use of the sample type detection module assembly of this embodiment:

installing a TIP groove 20 at the upper end of the assembled TIP head detection frame 10, inserting the lower end of the placing part 22 along the opening 11b correspondingly, positioning and fixing the detection frame body 11 and the TIP groove 20 by using a pin 150, and locking and fixing the detection frame body 11 and the TIP groove 20 by using a screw 160; mounting the emitter plate 30 on the first mounting post 1111; with second positioning hole 40b of receiving plate 40 corresponding to second positioning post 1122, receiving plate 40 is mounted on second mounting post 1121, and the sample type detection module assembly is completed.

When the TIP device is used, a TIP head containing a sample is placed in the TIP placing hole 20a of the TIP groove 20, the light emitting end 32 on the emitting plate 30 is electrically connected to emit light, the light reaches the corresponding light receiving end through the light inlet hole 111a, the light transmitting hole 12a, the sample and the light outlet hole 112a, and a detector analyzes the type of the sample according to light signals received by the light receiving end.

Example 3

As shown in fig. 6, the present embodiment provides an immunoassay analyzer 200, which includes a housing 201, the housing 201 having two cavities 201a spaced apart from each other, each cavity having two sample type detection module assemblies 100 as provided in embodiment 2 mounted therein.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way; the present invention can be smoothly implemented by those skilled in the art according to the drawings and the above description; however, those skilled in the art should understand that changes, modifications and variations made by the above-described technology can be made without departing from the scope of the present invention, and all such changes, modifications and variations are equivalent embodiments of the present invention; meanwhile, any changes, modifications, evolutions, etc. of the above embodiments, which are equivalent to the actual techniques of the present invention, still belong to the protection scope of the technical solution of the present invention.

Claims

1. The TIP head detection frame is characterized by comprising a detection frame body, a partition plate and a positioning mechanism, wherein the detection frame body is provided with a cavity, the cavity is provided with a first side wall and a second side wall which are arranged oppositely, at least one light inlet hole is formed in the first side wall, at least one coaxial light outlet hole is formed in the second side wall corresponding to the at least one light inlet hole, at least one light transmitting hole is formed in the partition plate correspondingly, and the partition plate is detachably installed in the cavity through the positioning mechanism so that the at least one light transmitting hole is located on the central axis of the corresponding light inlet hole and the central axis of the corresponding light outlet hole.

2. The TIP head detection frame according to claim 1, wherein the detection frame body further comprises a third side wall and a fourth side wall which are oppositely arranged, the third side wall and the fourth side wall are respectively and correspondingly provided with a slot, and two ends of the partition plate are detachably inserted into the slots.

3. The TIP head detection frame according to claim 2, wherein the positioning mechanism comprises at least one positioning pin and a fastener, the positioning pin is inserted into the partition plate, and two ends of the positioning pin are respectively fixedly connected with the first side wall and the second side wall through the fastener.

4. The TIP head detection frame of claim 3, wherein the light transmission hole is a rectangular hole, the light inlet hole and the light outlet hole are circular holes, and a central symmetry axis of the light transmission hole in a length direction intersects with a central connecting line of the corresponding light inlet hole and the corresponding light outlet hole.

5. A sample type detection module assembly, comprising a TIP groove, a transmitting plate, a receiving plate and the TIP head detection frame as claimed in any one of claims 2 to 4, wherein the cavity of the detection frame body is provided with an opening, the TIP groove is installed at the opening, the transmitting plate is provided with a transmitting surface, the receiving plate is provided with a receiving surface, the transmitting plate is installed at the outer side of the first side wall, the outer side surface of the first side wall is opposite to the transmitting surface, the receiving plate is installed at the outer side of the second side wall, the outer side surface of the second side wall is opposite to the receiving surface, at least one light emitting end is installed on the transmitting surface, the receiving surface is provided with light receiving ends corresponding to the light emitting ends one by one, and a group of corresponding light emitting ends and light receiving ends respectively correspond to a group of corresponding light inlet hole and light outlet hole, the central axis connecting line of the light inlet hole and the corresponding light outlet hole is superposed with the light path connecting line of the corresponding light emitting end and the corresponding light receiving end, a TIP placing hole is formed on the TIP groove, and the central line of the TIP placing hole is intersected with the light path connecting line of the corresponding light emitting end and the corresponding light receiving end.

6. The module assembly according to claim 5, wherein the TIP slot includes a mounting portion at both ends thereof and a placement portion between both ends thereof, the TIP placement hole is located in the placement portion, the mounting portions are fixedly connected to the upper ends of the third sidewall and the fourth sidewall, respectively, the outer contour of the lower end of the placement portion is adapted to the opening, and the lower end of the placement portion protrudes into the cavity through the opening.

7. The specimen type detection module assembly according to claim 6, wherein the mounting portion is fixed to upper ends of the third and fourth side walls by a positioning pin.

8. The sample type detection module assembly of claim 5, wherein a first gap is left between an outer side surface of the first sidewall and the emitting surface, and a second gap is left between an outer side surface of the second sidewall and the receiving surface.

9. The specimen type detection module assembly according to claim 8, wherein an outer side surface of the first side wall has at least one first mounting post having a height equal to the size of the first gap, one end of the first mounting post is fixedly connected to the outer side surface of the first side wall, and the emission plate is mounted to the other end of the first mounting post; the outer side face of the second side wall is provided with at least one second mounting column with the height equal to the size of the second gap, one end of the second mounting column is fixedly connected with the outer side face of the second side wall, and the receiving plate is mounted at the other end of the second mounting column.

10. The assembly as claimed in claim 8, wherein at least two second positioning posts are mounted on an outer side of the second sidewall, and a second positioning hole is formed on the emission plate and is matched with the second positioning posts.

11. An immunoassay analyzer comprising a housing having at least one cavity, each of said cavities housing at least one sample type detection module assembly according to any one of claims 5 to 10.