CN210711523U

CN210711523U - Duchenne muscular dystrophy mutant gene screening kit

Info

Publication number: CN210711523U
Application number: CN201921639506.1U
Authority: CN
Inventors: 牛冬; 汪滔
Original assignee: Nanjing Qizhen Genetic Engineering Co Ltd
Current assignee: Nanjing Qizhen Genetic Engineering Co Ltd
Priority date: 2019-09-29
Filing date: 2019-09-29
Publication date: 2020-06-09
Anticipated expiration: 2029-09-29

Abstract

The utility model discloses a Du's muscle dystrophies sudden change gene examination kit, comprises a box bod, the lower extreme fixed mounting of box body has the battery, the through-hole has been seted up to the lower extreme of box body, the through-hole is located box body lower extreme intermediate position, slide in the through-hole and cup jointed the pivot, the lower extreme fixed mounting of box body has the motor, the motor upper end is provided with the pivot, the welding of pivot upper end has square, square upper end joint has the bottom plate, the upper end of bottom plate bonds and has the supporting shoe. This scheme is through setting up sponge piece and supporting shoe placing the hole bottom, and the supporting shoe is elasticity material, can protect the reagent pipe to prevent that the reagent pipe from causing the reagent pipe to damage in the process bottom of placing with placing the hole pore wall collision, through facility motor, bottom plate, can let the intraductal liquid of reagent carry out centrifugal motion according to the demand, saved the centrifugation link to liquid in the experimentation, improved the work efficiency in the experimentation.

Description

Duchenne muscular dystrophy mutant gene screening kit

Technical Field

The utility model relates to a kit technical field specifically is a duchenne muscular dystrophy mutant gene screening kit.

Background

Duchenne muscular dystrophy is the most common severe muscular dystrophy disease in children, a fatal X-linked recessive genetic disease caused by dystrophy gene mutation, occurring mainly in boys. The incidence rate of 1/3500 is that the infant male survived for the first time usually has diseases in 3-5 years old, the muscular atrophy and weakness worsen gradually, the walking ability is lost in more than 12 years old, and most patients die due to respiratory tract infection and heart failure and exhaustion in 25-30 years old by depending on wheelchairs. The screening of Duchenne muscular dystrophy mutant gene is very necessary for children with muscular atrophy, myasthenia and walking disorder, and the screening can be carried out on the children with muscular atrophy, myasthenia and walking disorder, so that the patients can be treated in a targeted manner, and the lives of the patients are effectively prolonged.

The kit is detection equipment frequently used in the field of biological medicine, is frequently used in chemical experiments, cell experiments and gene experiment processes, and generally comprises a kit body and a cover body, but the kit with the structure has a simple structure and a single function, and only plays a role in storing reagents in the experiment process. Meanwhile, the reagent tube is used frequently in the experiment process, so that the bottom of the reagent tube may be damaged due to the placement of the reagent tube in the experiment process. Accordingly, there is a need for improvements in the art.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a duchenne muscle dystrophy mutation gene screening kit possesses and protects, saves the centrifugation link to liquid in the experimentation, has improved the advantage of the work efficiency in the experimentation, has solved the bottom of kit function singleness, reagent pipe because place the problem of improper damage.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a Du's muscle dystrophies sudden change gene screening kit, includes the box body, the lower extreme fixed mounting of box body has the battery, the through-hole has been seted up to the lower extreme of box body, the through-hole is located box body lower extreme intermediate position, sliding sleeve has the pivot in the through-hole, the lower extreme fixed mounting of box body has the motor, the motor upper end is provided with the pivot, the welding of pivot upper end has square piece, square piece's upper end joint has the bottom plate, the upper end of bottom plate bonds and has the supporting shoe, it places the hole to have seted up in the supporting shoe, sliding sleeve has the reagent pipe in placing the hole, the left end fixed mounting of box body.

Preferably, the right end of the box cover is provided with a clamping groove, the right end of the box body is fixedly connected with a clamping block, and the clamping block is clamped in the clamping groove.

Preferably, six support blocks are arranged and are of cylindrical structures and distributed on the bottom plate in an annular array.

Preferably, the lower extreme of bottom plate is provided with square groove, square piece of square inslot joint, the bottom plate is cylindrical.

Preferably, the lower end of the placing hole is connected with a sponge block in a contact manner, and the upper end of the sponge block is connected with a reagent tube.

Preferably, the battery, the motor and the switch are connected in series by a wire.

Compared with the prior art, the beneficial effects of the utility model are as follows:

1. the utility model discloses a setting up sponge piece and supporting shoe bottom placing the hole, the supporting shoe is elasticity material, can protect the reagent pipe to prevent that the reagent pipe from causing the reagent pipe to damage in the process bottom of placing with place the hole pore wall collision.

2. The utility model discloses a facility motor, bottom plate can let the intraductal liquid of reagent carry out centrifugal motion according to the demand, have saved the centrifugation link to liquid in the experimentation, have improved the work efficiency in the experimentation.

Drawings

FIG. 1 is a schematic structural view of the present invention;

fig. 2 is a top view of fig. 1 of the present invention;

fig. 3 is a circuit diagram of the motor of the present invention.

In the figure: 1. a box body; 2. a battery; 3. a through hole; 4. an electric motor; 5. a rotating shaft; 6. a square block; 7. a square groove; 8. a base plate; 9. a support block; 10. placing holes; 11. a sponge block; 12. a reagent tube; 13. a switch; 14. a box cover; 15. a card slot; 16. and (7) clamping blocks.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Examples

Please refer to fig. 1, a duchenne muscular dystrophy mutant gene screening kit, including box body 1, the lower extreme fixed mounting of box body 1 has battery 2, through-hole 3 has been seted up to the lower extreme of box body 1, through-hole 3 is located box body 1 lower extreme intermediate position, sliding sleeve has pivot 5 in the through-hole 3, the lower extreme fixed mounting of box body 1 has motor 4, belong to prior art, motor 4 upper end is provided with pivot 5, the welding of pivot 5 upper end has square 6, the upper end joint of square 6 has bottom plate 8, the upper end of bottom plate 8 bonds there is supporting shoe 9, it places hole 10 to have been seted up in the supporting shoe 9, sliding sleeve has reagent pipe 12 in placing hole 10, the left end fixed mounting of box body 1 has switch 13, the upper end of box body 1.

Referring to fig. 1, a clamping groove 15 is formed at the right end of the box cover 14, a clamping block 16 is fixedly connected to the right end of the box body 1, the clamping block 16 is clamped in the clamping groove 15, and the clamping groove 15 and the clamping block 16 are clamped in a matched manner to fix the box cover 14.

Referring to fig. 2, seven support blocks 9 are provided, and are cylindrical structures, made of elastic plastic materials, and distributed on the bottom plate 8 in an annular array, and the support blocks 9 have a supporting function.

Referring to fig. 1, a square groove 7 is formed at the lower end of the bottom plate 8, a square block 6 is clamped in the square groove 7, the bottom plate 8 is cylindrical, and the rotating shaft 5 can drive the bottom plate 8 to rotate through the cooperation of the square groove 7 and the square block 6.

Referring to fig. 1, the lower end of the placing hole 10 is connected with a sponge block 11 in a contact manner, the upper end of the sponge block 11 is connected with a reagent tube 12, and the reagent tube 12 is protected by the design of the sponge block 11.

Referring to fig. 3, the battery 2, the motor 4 and the switch 13 are connected in series by a wire, and the motor 4 can be controlled by the switch 13.

During the use, open lid 14, reagent pipe 12 is put into and is placed in hole 10, reagent pipe 12 bottom and sponge piece 11 contact, close lid 14, lid 14 passes through draw-in groove 15 and fixture block 16 cooperation joint, fix in box body 1 upper end, press switch 13 starter motor 4, pivot 5 rotates, it rotates to drive square piece 6, it rotates to drive bottom plate 8, it rotates to drive supporting shoe 9, it rotates to drive reagent pipe 12, produce centrifugal action, make liquid need not carry out centrifugal action at needs in the experimentation and just can use in reagent pipe 12, the experimental steps have been reduced, the experimental efficiency is improved.

The control mode of the present application is automatically controlled by a controller, the control circuit of the controller can be realized by simple programming by those skilled in the art, and the present application is common knowledge in the field, and the present application mainly protects the mechanical device, so the control mode and the circuit connection are not explained in detail in the present application.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A Duchenne muscular dystrophy mutant gene screening kit comprises a kit body (1), and is characterized in that: the lower end of the box body (1) is fixedly provided with a battery (2), the lower end of the box body (1) is provided with a through hole (3), the through hole (3) is positioned in the middle of the lower end of the box body (1), the through hole (3) is sleeved with a rotating shaft (5) in a sliding way, the lower end of the box body (1) is fixedly provided with an electric motor (4), the upper end of the electric motor (4) is provided with a rotating shaft (5), a square block (6) is welded at the upper end of the rotating shaft (5), a bottom plate (8) is clamped at the upper end of the square block (6), a supporting block (9) is bonded at the upper end of the bottom plate (8), a placing hole (10) is arranged in the supporting block (9), place in hole (10) and slide in the cover and connect reagent pipe (12), the left end fixed mounting of box body (1) has switch (13), the upper end of box body (1) articulates there is lid (14).

2. The duchenne muscular dystrophy mutant gene screening kit of claim 1, wherein: the right end of the box cover (14) is provided with a clamping groove (15), the right end of the box body (1) is fixedly connected with a clamping block (16), and the clamping block (16) is clamped in the clamping groove (15).

3. The duchenne muscular dystrophy mutant gene screening kit of claim 1, wherein: six support blocks (9) are cylindrical structures and are distributed on the bottom plate (8) in an annular array.

4. The duchenne muscular dystrophy mutant gene screening kit of claim 1, wherein: the lower extreme of bottom plate (8) is provided with square groove (7), square piece (6) of joint in square groove (7), bottom plate (8) are cylindrical.

5. The duchenne muscular dystrophy mutant gene screening kit of claim 1, wherein: the lower end of the placing hole (10) is connected with a sponge block (11) in a contact mode, and the upper end of the sponge block (11) is connected with a reagent tube (12).

6. The duchenne muscular dystrophy mutant gene screening kit of claim 1, wherein: the battery (2), the motor (4) and the switch (13) are connected in series through a lead.