CN210544738U

CN210544738U - Kit, reagent storage device and chemiluminescence immunoassay appearance

Info

Publication number: CN210544738U
Application number: CN201920580991.3U
Authority: CN
Inventors: 彭金华
Original assignee: Aite Biotechnology (shenzhen) Co Ltd
Current assignee: Aite Biotechnology (shenzhen) Co Ltd
Priority date: 2019-04-26
Filing date: 2019-04-26
Publication date: 2020-05-19
Anticipated expiration: 2029-04-26

Abstract

The utility model relates to a kit for install on the carousel that has mixing mechanism, include: the box body can be detachably connected with the turntable, and a through hole is formed in the box body; the containing bottle is used for containing a reagent and is rotatably arranged in the through hole, and the containing bottle in the through hole can be connected with the blending mechanism; when the turntable rotates, the containing bottles revolve around the rotation center of the turntable, and the blending mechanism drives the containing bottles to rotate in the through holes. When the containing bottle revolves, the blending mechanism drives the containing bottle to rotate in the through hole relative to the box body, namely the blending mechanism drives the containing bottle to rotate. Therefore, under the combined action of the rotating disc and the blending mechanism, the holding bottle simultaneously revolves and rotates, so that the reagent in the holding bottle forms turbulent flow to generate strong vortex, and finally, the automatic blending of the magnetic particle suspension reagent is realized.

Description

Kit, reagent storage device and chemiluminescence immunoassay appearance

Technical Field

The utility model relates to the technical field of medical equipment, especially, relate to a kit, reagent storage device and chemiluminescence immunoassay appearance.

Background

The full-automatic chemiluminescence immunoassay analyzer is equipment for analyzing by directly marking antigen and antibody with chemiluminescence reagent, can automatically complete a series of processes such as sampling, sample adding, reaction and detection, and the like, and reduces the manual operation error while improving the detection efficiency. The reagent storage device for storing and conveying the reagent is arranged on the full-automatic chemiluminescence immunoassay analyzer, generally, the reagent box on the traditional reagent storage device can only synchronously rotate along with the turntable, so that the reagent storage device does not have the function of uniformly mixing the reagent in the reagent box.

SUMMERY OF THE UTILITY MODEL

The utility model provides a technical problem how realize the automatic mixing of reagent in the holding bottle.

A kit for mounting on a carousel with a blending mechanism, comprising:

the box body can be detachably connected with the turntable, and a through hole is formed in the box body; and

the containing bottle is used for containing a reagent and is rotatably arranged in the through hole, and the containing bottle in the through hole can be connected with the blending mechanism;

when the turntable rotates, the containing bottles revolve around the rotation center of the turntable, and the blending mechanism drives the containing bottles to rotate in the through holes.

In one embodiment, a bottle rim and a first convex ring are arranged on the containing bottle, the bottle rim is positioned at the mouth of the containing bottle and protrudes for a set length relative to the outer surface of the containing bottle, the first convex ring is close to the bottle rim and protrudes for a set length relative to the outer surface of the containing bottle, and a gap between the bottle rim and the first convex ring forms an installation groove; the inner wall surface of the through hole is provided with a limiting part which protrudes for a set length relative to the inner wall surface, and the limiting part can be matched with the mounting groove to limit the position of the containing bottle in the through hole.

In one embodiment, the longitudinal section of the first collar includes a top edge extending along the axial direction of the container bottle and two inclined edges, one of the inclined edges is connected between one end of the top edge and the outer surface of the container bottle, the other inclined edge is connected between the other end of the top edge and the outer surface of the container bottle, and the two inclined edges respectively form an obtuse angle with the top edge.

In one embodiment, the containing bottle is further provided with a second convex ring, and the second convex ring is close to the bottom of the containing bottle and protrudes for a set length relative to the outer surface of the containing bottle.

In one embodiment, the bottom of the containing bottle is provided with a groove, and the groove is used for matching with the blending mechanism.

In one embodiment, the inner surface of the containing bottle is enclosed into a conical structure at the part close to the bottom of the containing bottle.

In one embodiment, the stirring device further comprises a stirring piece, one end of the stirring piece is connected with the inner surface of the containing bottle, and the other end of the stirring piece is suspended in the bottle cavity of the containing bottle.

In one embodiment, the box body is provided with a buckling piece used for being buckled and connected with the rotating disc; and/or the box body is also provided with a containing cavity for containing the reagent bottle.

A reagent storage device, comprising a turntable, a blending mechanism and any one of the reagent kit; the carousel along its circumference interval be provided with a plurality of be used for with box body complex wedge position, mixing mechanism install on the carousel with the position department that the wedge position corresponds.

A chemiluminescence immunoassay analyzer comprises the reagent storage device.

The utility model discloses a technical effect of an embodiment is: when the box body is arranged on the rotating disc and the rotating disc rotates around the rotating center, the containing bottle revolves around the rotating center of the rotating disc along with the box body; when the containing bottle revolves, the blending mechanism drives the containing bottle to rotate in the through hole relative to the box body, namely the blending mechanism drives the containing bottle to rotate. Therefore, under the combined action of the rotating disc and the blending mechanism, the holding bottle simultaneously revolves and rotates, so that the reagent in the holding bottle forms turbulent flow to generate strong vortex, and finally, the automatic blending of the magnetic particle suspension reagent is realized.

Drawings

FIG. 1 is a schematic diagram of the overall structure of a reagent storage device according to an embodiment;

FIG. 2 is a schematic view of the kit of FIG. 1 in a first view;

FIG. 3 is a schematic view of the reagent kit of FIG. 1 in a second view;

FIG. 4 is a schematic view of a portion of the reagent kit shown in FIG. 1 with the bottle removed;

FIG. 5 is a schematic view of the overall structure of the containment bottle of FIG. 1;

fig. 6 is a schematic cross-sectional structure of fig. 5.

Detailed Description

In order to facilitate understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. The preferred embodiments of the present invention are shown in the drawings. The invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "inner", "outer", "left", "right" and the like as used herein are for illustrative purposes only and do not represent the only embodiments.

Referring to fig. 1, a reagent storage device 10 according to an embodiment of the present invention includes a turntable 12, a blending mechanism 13, and a reagent cartridge 11. The carousel 12 is roughly discoid, and the border department of carousel 12 is provided with a plurality of wedges 14, and a plurality of wedges 14 set up along the circumference interval of carousel 12, and reagent box 11 can be fixed in this wedges 14, and when carousel 12 rotated around the rotation center of self, reagent box 11 revolved around this rotation center along with carousel 12, and mixing mechanism 13 installs the position department that corresponds with wedges 14 on carousel 12.

Referring to fig. 1 to 4, the reagent kit 11 includes a main body 100 and a containing bottle 200, the main body 100 is provided with a fastener 120, when the main body 100 is engaged with the wedge 14, the fastener 120 can be engaged with a slot provided on the rotating disc 12, so as to stably and reliably fix the main body 100 on the rotating disc 12, that is, the main body 100 and the rotating disc 12 form a detachable fastening connection relationship. The box body 100 is provided with a through hole 110 and a containing cavity 130, the through hole 110 penetrates through the upper surface and the lower surface of the box body 100, the through hole 110 is used for containing a containing bottle 200, and the containing bottle 200 can be used for containing a suspension reagent with magnetic particles; the chamber 130 may be a plurality and may be used to accommodate other reagent bottles 300, and the other reagent bottles 300 may be used to contain the relevant reagent solution therein.

The container bottle 200 may be substantially cylindrical, the container bottle 200 is rotatably disposed in the through hole 110, a bottle cap 240 may be disposed at the mouth of the container bottle 200, the bottle cap 240 is used to close the mouth of the container bottle 200 to prevent dust or other impurities from entering the magnetic particle suspension reagent in the container bottle 200, and the bottle cap 240 may be made of a plastic material. The bottom of the containing bottle 200 is provided with a groove 280, the groove 280 is matched with the protrusion on the blending mechanism 13, and the blending mechanism 13 can drive the containing bottle 200 to rotate in the through hole 110 through the matching of the groove 280 and the protrusion.

When the cartridge body 100 is mounted on the turntable 12 and the turntable 12 rotates around the rotation center, the containing bottle 200 revolves around the rotation center of the turntable 12 following the cartridge body 100; while the holding bottle 200 revolves, the kneading mechanism 13 drives the holding bottle 200 to rotate in the through hole 110 relative to the cartridge body 100, that is, the kneading mechanism 13 drives the holding bottle 200 to rotate. Therefore, through the combined action of the rotating disc 12 and the blending mechanism 13, the containing bottle 200 simultaneously revolves and rotates, so that the magnetic particle suspension reagent in the containing bottle 200 forms turbulent flow to generate strong vortex, the vortex pushes the magnetic particles to be always in a suspension state without generating precipitation, and finally, the automatic blending of the magnetic particle suspension reagent is realized.

Referring to fig. 1 and 2, 5 and 6, in some embodiments, the bottle 200 is provided with a rim 230 and a first collar 210, the rim 230 and the first collar 210 are both substantially annular structures, the rim 230 is located at the mouth of the bottle 200, the rim 230 radially protrudes a set length relative to the outer surface of the bottle 200, the first collar 210 is located near the rim 230, and the first collar 210 also radially protrudes a set length relative to the outer surface of the bottle 200. The length of the protrusion of the rim 230 with respect to the outer surface of the receiving bottle 200 may be greater than the length of the protrusion of the first collar 210 with respect to the outer surface of the receiving bottle 200. The bottle rim 230 and the first protruding ring 210 are arranged at intervals along the axial direction of the bottle 200, and the gap between the bottle rim 230 and the first protruding ring 210 forms a mounting groove 250. The inner wall surface of the through hole 110 is provided with a limiting portion, the limiting portion protrudes a set length relative to the inner wall surface of the through hole 110, and the limiting portion may also be in an annular structure. When the bottle 200 is accommodated in the through hole 110, the limiting portion is engaged with the mounting groove 250, the maximum distance that the bottle 200 moves downward close to the turntable 12 can be limited by the abutting relationship between the limiting portion and the first boss, and the maximum distance that the bottle 200 moves upward away from the turntable 12 can be limited by the abutting relationship between the limiting portion and the bottle rim 230. Therefore, the specific position of the receiving bottle 200 in the through hole 110 can be well defined by the engagement of the stopper portion with the mounting groove 250.

In some embodiments, the longitudinal cross-section of first male ring 210 may be substantially in the shape of an isosceles trapezoid. Specifically, the longitudinal section of the first collar 210 includes a top edge 211 and two oblique edges 212, the top edge 211 extends along the axial direction of the receiving bottle 200, that is, the top edge 211 extends along the vertical direction, one oblique edge 212a is connected between the upper end of the top edge 211 and the outer surface of the receiving bottle 200, the other oblique edge 212b is connected between the lower end of the top edge 211 and the outer surface of the receiving bottle 200, the two oblique edges 212 respectively form an obtuse angle with the top edge 211, and at this time, the two oblique edges 212 respectively incline at a certain angle with respect to the vertical direction. Because the two inclined edges 212 are inclined relative to the axial direction of the containing bottle 200, a certain pressure can be applied downwards to the containing bottle 200 in the process of placing the containing bottle 200 into the through hole 110, and when the limiting part is contacted with the first convex ring 210, the limiting part is easy to gradually slide into the mounting groove 250 along the inclined edge 212b far away from the bottle edge 230 and is matched with the mounting groove, so that the containing bottle 200 is accommodated in the through hole 110. In the process of taking the receiving bottle 200 out of the through hole 110, a certain pulling force can be applied upwards to the receiving bottle 200, and when the limiting part is in contact with the first convex ring 210, the limiting part can easily slide out of the mounting groove 250 gradually along the inclined edge 212a arranged close to the bottle edge 230 and release the matching relationship, so that the receiving bottle 200 can be taken out of the through hole 110.

The receiving bottle 200 is further provided with a second convex ring 220, the second convex ring 220 is disposed near the bottom of the receiving bottle 200, the second convex ring 220 protrudes a set length relative to the outer surface of the receiving bottle 200, and the second convex ring 220 may be a ring structure, i.e. the second convex ring 220 and the first convex ring 210 may be similar in structure. The first bulge loop 210 and the second bulge loop 220 are closer to the inner wall surface of the through hole 110 relative to other outer wall surfaces of the containing bottle 200, namely, a small clearance is kept between the through hole 110 and other parts of the containing bottle 200 relative to the first bulge loop 210 and the second bulge loop 220, and when the containing bottle 200 rotates, the first bulge loop 210 and the second bulge loop 220 can effectively prevent the containing bottle 200 from swinging violently to collide with the inner wall surface of the through hole 110, so that the rotation stability of the containing bottle 200 is ensured.

The inner surface of the container bottle 200 is surrounded by a conical structure 270 near the bottom of the container bottle 200, so that the size of the cavity of the container bottle 200 near the bottom decreases from top to bottom. This reduces the amount of magnetic particle suspension reagent remaining in the containment vial 200 during use.

In some embodiments, reagent cartridge 11 further comprises stirring member 260, one end of stirring member 260 is connected to the inner surface of containment vessel 200, and the other end of stirring member 260 is suspended in the vessel cavity of containment vessel 200. In the rotation process of the holding bottle 200, the stirring member 260 can stir the magnetic particle suspension reagent, thereby further increasing the turbulence of the magnetic particle suspension reagent and improving the uniform mixing effect of the magnetic particle suspension reagent.

The utility model also provides a chemiluminescence immunoassay appearance, this chemiluminescence immunoassay appearance includes foretell reagent storage device 10.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims

1. The utility model provides a kit for install on the carousel that has mixing mechanism, its characterized in that includes:

the containing bottle is used for containing a reagent and is rotatably arranged in the through hole, and the containing bottle positioned in the through hole can be connected with the blending mechanism;

2. The kit according to claim 1, wherein the container bottle is provided with a bottle rim and a first convex ring, the bottle rim is positioned at the mouth of the container bottle and protrudes a set length relative to the outer surface of the container bottle, the first convex ring is close to the bottle rim and protrudes a set length relative to the outer surface of the container bottle, and a gap between the bottle rim and the first convex ring forms a mounting groove; the inner wall surface of the through hole is provided with a limiting part which protrudes for a set length relative to the inner wall surface, and the limiting part can be matched with the mounting groove to limit the position of the containing bottle in the through hole.

3. The reagent kit according to claim 2, wherein the longitudinal section of the first collar comprises a top edge and two oblique edges, the top edge extends along the axial direction of the containing bottle, one of the oblique edges is connected between one end of the top edge and the outer surface of the containing bottle, the other oblique edge is connected between the other end of the top edge and the outer surface of the containing bottle, and the two oblique edges respectively form an obtuse angle with the top edge.

4. The kit according to claim 2, wherein the containing bottle is further provided with a second convex ring, and the second convex ring is close to the bottom of the containing bottle and protrudes for a set length relative to the outer surface of the containing bottle.

5. The kit according to claim 2, wherein the bottom of the holding bottle is provided with a groove, and the groove is used for matching with the blending mechanism.

6. The kit of claim 1, wherein the inner surface of the containment vessel is defined by a conical structure adjacent to the bottom of the containment vessel.

7. The kit of claim 1, further comprising a stirring member, one end of the stirring member being connected to the inner surface of the containment vial, the other end of the stirring member being suspended in the vial cavity of the containment vial.

8. The kit according to claim 1, wherein the box body is provided with a fastener for snap-fit connection with the rotary plate; and/or the box body is also provided with a containing cavity for containing the reagent bottle.

9. A reagent storage device comprising a carousel, a mixing mechanism, and a kit of any one of claims 1 to 8; the carousel along its circumference interval be provided with a plurality of be used for with box body complex wedge position, mixing mechanism install on the carousel with the position department that the wedge position corresponds.

10. A chemiluminescent immunoassay analyzer comprising the reagent storage device of claim 9.