CN210119422U - Diffusion test device - Google Patents

Diffusion test device Download PDF

Info

Publication number
CN210119422U
CN210119422U CN201920712375.9U CN201920712375U CN210119422U CN 210119422 U CN210119422 U CN 210119422U CN 201920712375 U CN201920712375 U CN 201920712375U CN 210119422 U CN210119422 U CN 210119422U
Authority
CN
China
Prior art keywords
water bath
cavity
diffusion
cover plate
bath jacket
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201920712375.9U
Other languages
Chinese (zh)
Inventor
陈玮
胡一川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Baiyi Health Technology Co Ltd
Original Assignee
Hangzhou Baiyi Health Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hangzhou Baiyi Health Technology Co Ltd filed Critical Hangzhou Baiyi Health Technology Co Ltd
Priority to CN201920712375.9U priority Critical patent/CN210119422U/en
Application granted granted Critical
Publication of CN210119422U publication Critical patent/CN210119422U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

The utility model provides a simple structure, small, convenient to use's diffusion test device can provide stable environment for diffusion test and osmotic membrane preparation. The diffusion test device comprises a base, a guide rail, a water bath jacket and a cover plate, wherein the water bath jacket and the guide rail are fixed on the base, the cover plate is connected with the guide rail in a sliding manner, the water bath jacket is provided with a containing cavity for containing a diffusion cell or a film making tool, the containing cavity is provided with an opening, and when the water bath jacket and the cover plate are combined, the cover plate covers the opening of the containing cavity and the containing cavity is sealed; when the water bath jacket is separated from the cover plate, the cavity opening is exposed. The cover plate can slide on the guide rail to realize the combination or separation with the water bath jacket.

Description

Diffusion test device
Technical Field
The utility model relates to a film permeability test field specifically relates to a diffusion test device.
Background
The following background is provided to aid the reader in understanding the present invention and is not admitted to be prior art.
The membrane permeability test is used to detect the rate of small molecule substances passing through the membrane. Firstly, preparing a permeable membrane for a diffusion test, installing the permeable membrane in a diffusion cell, and then placing the diffusion cell provided with the permeable membrane in a constant temperature environment for the diffusion test. A water bath jacket is typically used to maintain the diffusion cell at a constant temperature. Among the current diffusion test device, the water bath presss from both sides the chamber that the cover is used for holding the diffusion cell and communicates with the external world, and when carrying out the diffusion test, the temperature in diffusion cell receives external environment's influence easily to influence diffusion test's stability and degree of accuracy.
SUMMERY OF THE UTILITY MODEL
To the problem, the utility model provides a simple structure, small, convenient to use's diffusion test device can provide stable environment for diffusion test and osmotic membrane preparation.
A diffusion test device comprises a base, a guide rail, a water bath jacket and a cover plate, wherein the water bath jacket and the guide rail are fixed on the base, the cover plate is connected with the guide rail in a sliding manner, the water bath jacket is provided with a containing cavity for containing a diffusion cell or a film making tool, the containing cavity is provided with an opening, and when the water bath jacket and the cover plate are combined, the cover plate covers the opening of the containing cavity and seals the containing cavity; when the water bath jacket is separated from the cover plate, the cavity opening is exposed. The cover plate can slide on the guide rail to realize the combination or separation with the water bath jacket. When the cover plate is combined with the water bath clamping sleeve, the containing cavity is sealed, so that the diffusion test or the preparation of the permeation film is carried out in a constant temperature and humidity environment, and the external interference is reduced. Preferably, the cover plate is hermetically connected to the water bath jacket when the water bath jacket is combined with the cover plate. Preferably, the diffusion cell/membrane maker has one, two or more. Preferably, the diffusion cell is a horizontal diffusion cell and/or a vertical diffusion cell. Preferably, a temperature sensor is arranged in the accommodating cavity. Preferably, a humidity sensor is arranged in the accommodating cavity.
Furthermore, one end of the containing cavity is opened, and the guide rail is positioned on one side of the opening of the containing cavity; or the two ends of the containing cavity are opened, and guide rails are respectively arranged on the two sides of the opening of the containing cavity. Preferably, the guide rail is a convex strip arranged on the base, a slide block is arranged on the convex strip, the slide block is in sliding connection with the convex strip, and the cover plate is fixedly connected with the slide block. That is to say, the apron passes through slider and guide rail sliding connection, and when the slider slided on the sand grip, drive the apron and remove along the guide rail. Preferably, the slider has the recess that is used for with the sand grip joint, and the slider passes through recess and sand grip sliding connection.
Further, the diffusion test device is provided with a driving mechanism for driving the sliding block to move on the convex strip.
Further, a clamping piece is arranged on the water bath jacket, the clamping piece is rotatably connected with the water bath jacket, the clamping piece is provided with a first position and a second position, and when the clamping piece is located at the first position, the clamping piece can clamp the water bath jacket and the cover plate; the cover plate is separable from the water bath jacket when the clamp is in the second position. Through the holder, increase the leakproofness between apron and the water bath cover.
Furthermore, the water bath jacket is provided with a cavity for containing water, the cavity is positioned at the outer edge of the containing cavity, and two ends of the cavity are sealed. Preferably, the two ends of the cavity and the cavity are flush. Preferably, the axis of the cavity and the axis of the cavity are located on the same line.
Further, an electric heating wire is arranged in the cavity; or, the diffusion test device further comprises a heating device, the cavity is provided with a water inlet pipe and a water outlet pipe, and the water inlet pipe and the water outlet pipe are respectively connected with the heating device. Preferably, the water inlet pipe is provided with a first water pump for driving water to flow from the heating device to the cavity, and the water outlet pipe is provided with a second water pump for driving water to flow from the cavity to the heating device. The water in the cavity is heated by the electric heating wire to realize constant temperature; or the water in the cavity is heated by a heating device arranged outside the cavity, and the circulation of the hot water is realized by a water inlet pipe and a water outlet pipe, so that the temperature in the water bath jacket is kept constant.
Furthermore, a flat plate for placing a diffusion cell or a film making tool is arranged in the accommodating cavity, and the flat plate is fixedly connected with the inner wall of the accommodating cavity. Preferably, the plane of the plate is parallel to the axis of the chamber. Preferably, the plane of the plate is parallel to the horizontal plane.
Further, the diffusion test device comprises a container for accommodating the diffusion cell, and an ultrasonic generator is mounted at the bottom of the container. Thus, after the diffusion cell is placed in the container, the ultrasonic wave generated by the ultrasonic generator can promote the diffusion of the micromolecule substances in the diffusion cell.
The utility model has the advantages that:
1. the sealing of the jacket water bath cavity is realized through the combination of the cover plate and the water bath jacket, so that the diffusion test or the preparation of the permeable membrane can be carried out in a closed environment with constant temperature and humidity, the interference of the external environment is avoided, and the accuracy of the diffusion test is improved; for the preparation of the permeable membrane, the closed cavity is beneficial to keeping the temperature and the atmosphere constant, so that the surface of the permeable membrane is flat.
2. A plurality of horizontal diffusion cells and/or vertical diffusion cell can be placed simultaneously in holding the appearance chamber of water bath jacket to can carry out a plurality of or multiple diffusion test simultaneously under the same environment, reduce diffusion test device's area on the one hand, on the other hand can improve diffusion test's efficiency.
3. The cover plate is driven by the driving mechanism to slide relative to the guide rail, so that the combination and separation of the water bath jacket and the cover plate are automated or semi-automated, and manual operation is reduced.
Drawings
Fig. 1 is an overall appearance view of the diffusion test apparatus according to an embodiment of the present invention, when the cover plate is separated from the water bath jacket.
FIG. 2 is an overall external view of the diffusion test apparatus of FIG. 1 from another angle.
FIG. 3 is a cross-sectional view of the diffusion test apparatus of FIG. 1.
Fig. 4 is a schematic view of the connection between the conveyor belt and the cover plate according to an embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to specific embodiments.
A diffusion test device is shown in figure 1 and comprises a base 1, a guide rail, a water bath jacket 3 and a cover plate 4, wherein the water bath jacket 3 and the guide rail are both fixed on the base 1, the cover plate 4 is in sliding connection with the guide rail, the water bath jacket is provided with a containing cavity 301 for containing a diffusion cell 5 or a film making tool, the containing cavity 301 is provided with an opening, when the water bath jacket 3 is combined with the cover plate 4, the cover plate 4 covers the opening of the containing cavity, the cover plate 4 is in air-tight connection with the water bath jacket 3, and the containing cavity 301; when the water bath jacket 3 is separated from the cover plate 4, the cavity opening is exposed. The cover plate can slide on the guide rail to realize the combination or separation with the water bath jacket. When the cover plate is combined with the water bath clamping sleeve, the containing cavity is sealed, so that the diffusion cell can be isolated from the outside and kept at a constant temperature for a diffusion test, and the influence of the fluctuation of the external environment on the diffusion test is avoided; for osmotic membrane preparation, if the organic solvent used for preparing the osmotic membrane volatilizes too fast, the surface of the osmotic membrane is not smooth, a membrane preparation tool is placed in a closed containing cavity, constant temperature and atmosphere balance are kept in the osmotic membrane preparation process, the organic solvent volatilizes stably, and therefore the preparation of a smooth osmotic membrane is facilitated.
The diffusion cell or the membrane maker has one, two or more. The diffusion cell may be a horizontal diffusion cell and/or a vertical diffusion cell. For example, as shown in fig. 2, the chamber has two horizontal diffusion cells 501 and four vertical diffusion cells 502. Therefore, a plurality of diffusion cells/film making tools can share one water bath jacket, so that the whole volume of the diffusion device is favorably reduced, the occupied area is reduced, the accuracy of a diffusion test is favorably improved, and the diffusion test efficiency is improved. For example, to test and compare the permeability of a plurality of permeable membranes, diffusion cells with different permeable membranes mounted therein may be placed in a water bath jacket and simultaneously subjected to a diffusion test. Because the environments of the diffusion cells are consistent, the data are more accurate when the permeability of the permeable membrane is compared.
In some embodiments, a temperature sensor is disposed within the cavity 301; a humidity sensor is arranged in the cavity 301. The diffusion test device is also provided with a display screen for displaying the temperature and the humidity in the cavity, and the display screen is electrically connected with the temperature sensor and the humidity sensor.
In some embodiments, such as shown in FIG. 1, the chamber 301 is open at one end and the rail is located on one side of the chamber opening of the water bath jacket. In some embodiments, the cavity may be open at both ends, and guide rails are respectively disposed at both sides of the cavity opening.
In some embodiments, for example, as shown in fig. 1, the guide rail is a protruding strip 201 disposed on the base, a sliding block 202 is disposed on the protruding strip 201, the sliding block 202 has a groove for engaging with the protruding strip 201, the sliding block is slidably connected with the protruding strip 201 through the groove, and the cover plate 4 is fixedly connected with the sliding block 202. That is to say, the apron passes through slider and guide rail sliding connection, and when the slider slided on the sand grip, drive the apron and remove along the guide rail.
In some embodiments, the diffusion test apparatus has a driving mechanism for driving the slider to move on the ribs. For example, as shown in fig. 4, the driving mechanism may include a driving wheel (not shown), a driven wheel (not shown) and a motor (not shown) for driving the driving wheel to rotate, the driving wheel and the driven wheel are connected through a conveyor belt 9, and the conveyor belt 9 is fixedly connected with the sliding block 202 through a fixing plate 203. When the driving wheel rotates under the driving of the motor, the conveyor belt drives the sliding block to move on the guide rail, so that the cover plate is close to the water bath jacket until the cover plate is hermetically connected with the water bath jacket and the containing cavity is sealed, and the motor drives the driving wheel to stop rotating; or the cover plate is far away from the water bath jacket, the opening of the containing cavity is exposed, and the motor drives the driving wheel to stop rotating, so that the diffusion cell or the film making tool can be conveniently put in or taken out. In some embodiments, the diffusion testing apparatus is further provided with a control system for controlling the start and stop of the motor and controlling the direction of rotation of the motor.
In some embodiments, such as shown in fig. 1 and 2, the water bath jacket is provided with an outer rim 6 at the opening of the receiving chamber, the outer rim being provided with an annular groove 601 on the side facing the cover plate for receiving the sealing ring. The sealing ring is used for improving the sealing performance between the cover plate and the water bath jacket.
In some embodiments, the water bath jacket is provided with a clamping piece 7, the clamping piece 7 is rotatably connected with the water bath jacket 3, the clamping piece 7 has a first position and a second position, and when the clamping piece 7 is at the first position, the clamping piece can clamp the water bath jacket and the cover plate; when the clamp 7 is in the second position, the cover plate can be separated from the water bath jacket.
In some embodiments, the water bath jacket has a cavity 302 for containing water, the cavity 302 is located at the outer edge of the cavity 301, and the two ends of the cavity 302 are closed, as shown in fig. 3. The two ends of the cavity 301 and the cavity 302 are flush. The axis of the cavity 301 and the axis of the cavity 302 are located on the same line. For example, as shown in fig. 3, the water bath jacket comprises a sleeve 303, a first fixing plate 304 and a second fixing plate 305, wherein one end of the sleeve 303 is hermetically connected with the first fixing plate 304, and the other end of the sleeve 303 is hermetically connected with the second fixing plate 305. The sleeve comprises an inner sleeve 3031 and an outer sleeve 3032 sleeved outside the inner sleeve, the inner sleeve 3031 forms a cavity 301 for containing a diffusion cell or a membrane preparation tool, and a cavity 302 for containing water is formed between the inner sleeve 3031 and the outer sleeve 3032. One end of the cavity 301 is covered with the first fixing plate 304 to form a closed end, and the other end of the cavity 301 is opened. One end of the chamber 302 is covered by a first fixing plate 304 and the other end of the chamber 302 is covered by a second fixing plate 305, so that both ends of the chamber 302 are closed. An opening 3051 is formed in the second fixing plate 305, and the opening 3051 is aligned and matched with the inner sleeve 3031 to form a cavity opening. The second retainer panel 305 forms an outer edge at the cavity opening.
In some embodiments, as shown in fig. 3, a connecting rod 306 is disposed between the first fixing plate 304 and the second fixing plate 305, and both ends of the connecting rod 306 are connected to the first fixing plate 304 and the second fixing plate 305, respectively. Thus, the connection stability among the sleeve, the first fixing plate and the second fixing plate is increased.
In some embodiments, a heating wire is disposed within the cavity; or, the diffusion test device also comprises a heating device, the cavity is provided with a water inlet pipe and a water outlet pipe, the water inlet pipe and the water outlet pipe are respectively communicated with the cavity, and the water inlet pipe and the water outlet pipe are respectively connected with the heating device; the water inlet pipe is provided with a first water pump for driving water to flow from the heating device to the cavity, and the water outlet pipe is provided with a second water pump for driving water to flow from the cavity to the heating device. The water in the cavity is heated by the electric heating wire to realize constant temperature, or the water in the cavity is heated by a heating device arranged outside the cavity. The water in the cavity enters the heating device through the water outlet pipe and enters the cavity through the water inlet pipe after being heated.
In some embodiments, as shown in fig. 1 and 3, a flat plate 8 for placing a diffusion cell or a film-making tool is arranged in the cavity, and the flat plate 8 is fixedly connected with the inner wall of the cavity 301. The plane of the plate 8 is parallel to the axis of the cavity 301. The plate 8 lies in a plane parallel to the horizontal plane. The flat plate is beneficial to the stable placement of the diffusion cell or the film-making tool.
In some embodiments, the diffusion test apparatus includes a vessel for housing a diffusion cell, the bottom of the vessel being equipped with an ultrasonic generator. Thus, after the diffusion cell is placed in the container, the ultrasonic wave generated by the ultrasonic generator can promote the diffusion of the micromolecule substances in the diffusion cell. Similar to mechanical stirring, the intensity of the ultrasonic field generated by the ultrasonic generator is not uniform, the energy in the liquid is not uniformly distributed, and the generated current reduces the diffusion layer, so that the diffusion speed is improved. The ultrasonic wave is beneficial to the diffusion of the substance no matter the direction of the ultrasonic wave is the same as, opposite to or perpendicular to the diffusion direction. When the diffusion cell is used, the diffusion cell is firstly placed in the container, and then the diffusion cell and the container are placed in the containing cavity together.
The embodiments described in this specification are merely illustrative of implementations of the inventive concepts, and the scope of the invention should not be considered limited to the specific forms set forth in the embodiments, but rather the scope of the invention is intended to include equivalent technical means as would be understood by those skilled in the art from the inventive concepts.

Claims (10)

1. A diffusion test device is characterized by comprising a base, a guide rail, a water bath jacket and a cover plate, wherein the water bath jacket and the guide rail are fixed on the base; when the water bath jacket is separated from the cover plate, the cavity opening is exposed.
2. The diffusion test apparatus of claim 1, wherein the cover plate is hermetically sealed to the water bath jacket when the water bath jacket is assembled with the cover plate.
3. The diffusion test apparatus of claim 1, wherein the chamber is open at one end and the guide track is located on one side of the chamber opening; or the two ends of the containing cavity are opened, and guide rails are respectively arranged on the two sides of the opening of the containing cavity.
4. The diffusion test apparatus of claim 1, wherein the guide rails are ribs disposed on the base, the ribs having sliders thereon, the sliders being slidably connected to the ribs, and the cover being fixedly connected to the sliders.
5. The diffusion test apparatus of claim 4, wherein the diffusion test apparatus has a drive mechanism for driving the slider to move on the ribs.
6. The diffusion test apparatus of claim 1, wherein the water bath jacket has a clamping member mounted thereon, the clamping member being rotatably connected to the water bath jacket, the clamping member having a first position and a second position, the clamping member being capable of clamping the water bath jacket and the cover plate when the clamping member is in the first position; the cover plate is separable from the water bath jacket when the clamp is in the second position.
7. The diffusion test device of claim 1, wherein the water bath jacket has a cavity for holding water, the cavity is located at the outer edge of the cavity, and both ends of the cavity are closed.
8. The diffusion tester of claim 7, wherein the chamber has an electrical heating wire disposed therein; or, the diffusion test device further comprises a heating device, the cavity is provided with a water inlet pipe and a water outlet pipe, and the water inlet pipe and the water outlet pipe are respectively connected with the heating device.
9. The diffusion test device of claim 1, wherein a flat plate for holding a diffusion cell or a filming tool is disposed in the chamber and is fixedly connected to an inner wall of the chamber.
10. The diffusion test apparatus of claim 1, comprising a vessel for housing the diffusion cell, the bottom of the vessel being equipped with an ultrasonic generator.
CN201920712375.9U 2019-05-17 2019-05-17 Diffusion test device Active CN210119422U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201920712375.9U CN210119422U (en) 2019-05-17 2019-05-17 Diffusion test device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201920712375.9U CN210119422U (en) 2019-05-17 2019-05-17 Diffusion test device

Publications (1)

Publication Number Publication Date
CN210119422U true CN210119422U (en) 2020-02-28

Family

ID=69614380

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201920712375.9U Active CN210119422U (en) 2019-05-17 2019-05-17 Diffusion test device

Country Status (1)

Country Link
CN (1) CN210119422U (en)

Similar Documents

Publication Publication Date Title
US5192503A (en) Probe clip in situ assay apparatus
CN108465612A (en) A kind of automatically dropping glue and glue point detection device and its dispensing and characterization processes
US4812216A (en) Method of handling and transporting a transfer membrane used in a blotting apparatus
CN208485868U (en) Hybridization instrument and molecular detection system
US20150185181A1 (en) Electrophoresis gel cassette
CN107957364A (en) A kind of automatic staining device
CN210119422U (en) Diffusion test device
US20150219597A1 (en) Method of manufacturing an electrophoresis cassette
US5882495A (en) Electrophoresis system
WO2013180641A1 (en) Method of manufacturing an electrophoresis cassette
CN102749369A (en) High-efficiency and high-sensitivity biomacromolecule film transferring and dyeing system and equipment
CN110823883A (en) Automatic colorimetric analyzer
US20150136605A1 (en) Electrophoresis tray and a method of running an electrophoresis experiment
WO2014007720A1 (en) An electrophoresis gel unit comprising a flat gel member attached to a support
EP0155907B1 (en) Electrophoretic apparatus
JP2021530690A (en) Automated sample deposition and staining system and related methods
CN214384586U (en) Automatic headspace sample injector
CN113278517A (en) Portable integrated POCT nucleic acid rapid detector
CN209745986U (en) Qualitative/quantitative biochip detection system
CN209745987U (en) Qualitative/quantitative biochip detection system
CN112604727A (en) Multifunctional test tube rack for laboratory
CN208076386U (en) A kind of holder of accurate positioning
CN109668880A (en) Formaldehyde examination device
CN218290959U (en) Immune cell culture device
CN216051390U (en) Food synthetic pigment short-term test box

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant