CN210026313U - Portable 3D biological printing equipment - Google Patents
Portable 3D biological printing equipment Download PDFInfo
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- CN210026313U CN210026313U CN201920638703.5U CN201920638703U CN210026313U CN 210026313 U CN210026313 U CN 210026313U CN 201920638703 U CN201920638703 U CN 201920638703U CN 210026313 U CN210026313 U CN 210026313U
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Abstract
The utility model provides a portable 3D biological printing device, which comprises a base, a first Z-axis motion module, a second Z-axis motion module, an X-axis motion module, a double-nozzle device, a Y-axis motion module and a printing platform, wherein the first Z-axis motion module and the second Z-axis motion module are fixed on two opposite sides of the base; two ends of the X-axis movement module are respectively and slidably fixed on the first Z-axis movement module and the second Z-axis movement module; the double-nozzle device comprises a high-temperature nozzle structure and a normal-temperature nozzle structure; the double-nozzle device is slidably fixed on the X-axis movement module; the printing platform is positioned below the double-nozzle device and is slidably fixed on the Y-axis movement module, and the Y-axis movement module is fixed on the base. The utility model can print the support structure and the active filler simultaneously by arranging the double-nozzle device, thereby improving the printing efficiency; set up X axle motion module, Y axle motion module and two Z axle motion modules and mutually support, it is little to print the shaping error, and printing apparatus stable in structure dismantles the convenience, portable.
Description
Technical Field
The utility model belongs to the technical field of the biological printing technique and specifically relates to a biological printing apparatus of portable 3D is related to.
Background
The 3D printing technology is a novel manufacturing technology developed based on a digital model, and the 3D printing industry makes great progress in various fields at present, and also in the biological field. The 3D biological printing technology can mix and print biological materials, cells and growth factors by regulating and controlling a bracket structure, cell distribution and biological signal molecules, the process is that a three-dimensional model reconstructed or designed by medical image data is read in firstly, the model is dispersed into a plurality of layers, a computer controls a printing nozzle to print biological ink formed by the biological materials or the cells layer by layer, and the process is repeated continuously until the three-dimensional tissue precursor is printed. Subsequently, the cells begin to reorganize and fuse, forming new tissue structures such as blood vessels.
Currently, biological 3D printing technologies are mainly divided into two main categories: ink jet molding techniques and extrusion molding techniques. The pneumatic piston extrusion nozzle utilizes compressed gas to provide continuous air pressure power to push the biological printing material in the piston extrusion nozzle, so that the biological printing material is continuously extruded and molded from the micro-nozzle. The pneumatic extrusion molding has the advantages of wide range of molding materials, high flexibility, convenient control and the like.
However, the existing bioprinting equipment adopting a fixed molding platform has the following disadvantages: due to the limitation of cell printing technology, most of the existing cell three-dimensional printing technologies operate cells and materials with single components to construct simpler structures, and are limited to certain simple tissues, such as bone tissues, skin tissues, muscle bond tissues and the like; the equipment volume is relatively large, and the equipment is inconvenient to move and is matched with special equipment in the biological field, such as an ultra-clean operation table, a sterilization table and the like.
SUMMERY OF THE UTILITY MODEL
In order to solve the problem, the utility model provides a biological printing apparatus of portable 3D has and to print multiple macromolecular material simultaneously, print efficient, print characteristics such as the precision is high, equipment volume is little portable.
The technical scheme is as follows: the utility model provides a portable 3D biological printing device, which comprises a base, a first Z-axis motion module, a second Z-axis motion module, an X-axis motion module, a double-nozzle device, a Y-axis motion module and a printing platform; the first Z-axis motion module and the second Z-axis motion module are arranged in parallel and fixed on two opposite sides of the base; two ends of the X-axis movement module are respectively and slidably fixed on the first Z-axis movement module and the second Z-axis movement module; the double-nozzle device comprises a high-temperature nozzle structure and a normal-temperature nozzle structure which are respectively fixed on the fixing plate; the double-nozzle device is slidably fixed on the X-axis movement module through a fixing plate; the printing platform is positioned below the double-nozzle device and is fixed on the Y-axis movement module in a sliding manner, and the Y-axis movement module is fixed on the base.
Furthermore, the X-axis movement module comprises an X-axis motor, an X-axis screw rod and an X-axis fixing seat which is sleeved on the X-axis screw rod in a threaded manner, and the X-axis motor is connected with the X-axis screw rod through an X-axis coupler; the X-axis movement module also comprises an X-axis slide rail parallel to the X-axis screw rod; an X-axis sliding block which is embedded on the X-axis sliding rail in a sliding manner is fixed on the X-axis fixing seat; the double-nozzle device is fixed on the X-axis fixing seat through the fixing plate.
Furthermore, the X-axis motion module also comprises an X-axis motor connecting piece for fixing an X-axis motor, an X-axis fixing end and an X-axis supporting end for fixing an X-axis screw rod; the X-axis fixed end is fixed on the shell of the X-axis movement module through an X-axis fixed end connecting piece; an X-axis limit switch for limiting the displacement of the X-axis sliding block is arranged on the X-axis fixed end connecting piece; and the X-axis supporting end is fixed on the shell of the X-axis movement module through an X-axis supporting end connecting piece.
Further, the high-temperature spray head structure comprises a heat-insulating shell and a detachable first needle cylinder positioned in the heat-insulating shell; the top of the first needle cylinder is connected with a first adapter, the first adapter is connected with the air cylinder through an air pipe, and the bottom of the first needle cylinder is provided with a first nozzle; the heat-insulation shell is provided with a first threaded hole, and the high-temperature spray head structure is fixed on the fixing plate through the first threaded hole.
Furthermore, a heating element and a heat-sensitive sensor are arranged in the heat-insulating shell.
Further, the heating element is a heating rod, and the thermosensitive sensor is a thermocouple.
Further, the normal-temperature spray head structure comprises a first fixing piece, a second fixing piece and a second needle cylinder positioned in the openings of the first fixing piece and the second fixing piece; the top of the second needle cylinder is connected with a second adapter, the second adapter is connected with the air cylinder through an air pipe, and the bottom of the second needle cylinder is provided with a second nozzle; and a second threaded hole is formed in the first fixing piece, and the second needle cylinder is fixed on the fixing plate through the second threaded hole.
Further, the first Z-axis movement module comprises a first Z-axis motor, a first Z-axis screw rod and a first Z-axis fixing seat which is sleeved on the first Z-axis screw rod in a threaded manner, and the first Z-axis motor is connected with the first Z-axis screw rod through a first Z-axis coupler; the first Z-axis movement module also comprises a first Z-axis slide rail parallel to the first Z-axis screw rod; a first Z-axis sliding block which is embedded outside the first Z-axis sliding rail in a sliding manner is fixed on the first Z-axis fixing seat; one end of the shell of the X-axis motion module is slidably fixed on the first Z-axis fixed seat; the first Z-axis motion module further comprises a first Z-axis motor connecting piece used for fixing a first Z-axis motor, a first Z-axis fixing end used for fixing a first Z-axis screw rod and a first Z-axis supporting end; the first Z-axis fixed end is fixed on the shell of the first Z-axis motion module through a first Z-axis fixed end connecting piece; a first Z-axis limit switch for limiting the displacement of the first Z-axis slide block is arranged on the first Z-axis fixed end connecting piece; the first Z-axis supporting end is fixed on a shell of the first Z-axis movement module through a first Z-axis supporting end connecting piece.
Further, the second Z-axis movement module comprises a second Z-axis motor, a second Z-axis screw rod and a second Z-axis fixing seat which is sleeved on the second Z-axis screw rod in a threaded manner, and the second Z-axis motor and the second Z-axis screw rod are connected through a second Z-axis coupler; the second Z-axis motion module also comprises a second Z-axis slide rail parallel to the second Z-axis screw rod; a second Z-axis sliding block which is embedded outside the second Z-axis sliding rail in a sliding manner is fixed on the second Z-axis fixing seat; one end of the shell of the X-axis motion module is slidably fixed on the second Z-axis fixed seat; the second Z-axis motion module also comprises a second Z-axis motor connecting piece used for fixing a second Z-axis motor, a second Z-axis fixing end used for fixing a second Z-axis screw rod and a second Z-axis supporting end; the second Z-axis fixed end is fixed on the shell of the second Z-axis motion module through a second Z-axis fixed end connecting piece; a second Z-axis limit switch for limiting the displacement of the second Z-axis slide block is arranged on the second Z-axis fixed end connecting piece; and the second Z-axis supporting end is fixed on the shell of the second Z-axis movement module through a second Z-axis supporting end connecting piece.
Furthermore, the Y-axis movement module comprises a Y-axis motor, a Y-axis screw rod and a Y-axis fixing seat which is sleeved on the Y-axis screw rod in a threaded manner, and the Y-axis motor is connected with the Y-axis screw rod through a Y-axis coupler; the Y-axis motion module also comprises a Y-axis slide rail parallel to the Y-axis screw rod; a Y-axis sliding block which is embedded outside the Y-axis sliding rail in a sliding manner is fixed on the Y-axis fixing seat; the printing platform is slidably fixed on the Y-axis fixing seat; the Y-axis motion module also comprises a Y-axis motor connecting piece for fixing a Y-axis motor, a Y-axis fixed end and a Y-axis supporting end for fixing a Y-axis screw rod; the Y-axis fixed end is fixed on the shell of the Y-axis movement module through a Y-axis fixed end connecting piece; a Y-axis limit switch for limiting the displacement of the Y-axis slide block is arranged on the Y-axis fixed end connecting piece; and the Y-axis supporting end is fixed on the shell of the Y-axis movement module through a Y-axis supporting end connecting piece.
Has the advantages that: the utility model has the advantages that the high-temperature spray head structure and the normal-temperature spray head structure are arranged, the supporting structure and the active filler are respectively printed simultaneously, the defect of poor three-dimensional printing forming performance of common hydrogel materials is overcome, the printing efficiency is improved, the cell survival rate is high, and the application range is wide; the first Z-axis motion module, the second Z-axis motion module, the X-axis motion module and the Y-axis motion module are arranged to be matched with each other, so that the printing forming error is small; meanwhile, each motion module is formed by sleeving a shaft structure, and the printing equipment is stable in structure, convenient to detach, convenient to carry and simple to operate.
Drawings
Fig. 1 is a schematic structural view of the 3D bioprinting apparatus of the present invention;
FIG. 2 is a schematic view of the internal structure of the X-axis motion module of the present invention;
FIG. 3 is a three-dimensional structure diagram of the inside of the X-axis motion module of the present invention;
FIG. 4 is a schematic structural view of an X-axis limit switch, an X-axis limit switch connecting piece and an X-axis fixing seat connecting piece in the X-axis motion module of the present invention;
FIG. 5 is a front view of the dual sprinkler arrangement of the present invention;
FIG. 6 is an exploded view of a part of the structure of the dual nozzle device of the present invention;
fig. 7 is a schematic view of the structure of the heat preservation shell of the present invention.
In the figure, 1-X axis motion module, 101-X axis motor, 102-X axis motor connector, 103-X axis coupler, 104-X axis screw rod, 105-X axis fixed end, 106-X axis limit switch, 107-X axis limit switch connector, 109-X axis fixed seat, 112-X axis supporting end, 114-X axis fixed end connector, 115-X axis guide rail, 116-X axis slide block, 118-X axis supporting end connector, 2-Y axis motion module, 3-first Z axis motion module, 4-high temperature spray head structure, 401-first syringe, 402-first adapter, 403-heat preservation shell, 404-first threaded hole, 405-third threaded hole, 406-first spray nozzle, 407-fourth threaded hole, 5-normal temperature spray head structure, 501-second syringe, 502-second adapter, 503-first fixing piece, 504-second fixing piece, 505-second threaded hole, 506-second nozzle, 6-fixing plate, 7-printing platform, 8-base, 901-heating element, 902-heat sensor, and 10-second Z-axis movement module.
Detailed Description
The utility model provides a portable 3D biological printing device, as shown in figure 1, comprising a base 8, a first Z-axis motion module 3, a second Z-axis motion module 10, an X-axis motion module 1, a double-nozzle device, a Y-axis motion module 2 and a printing platform 7; the first Z-axis motion module 3 and the second Z-axis motion module 10 are arranged in parallel and fixed at two opposite sides of the base 8; two ends of the X-axis motion module 1 are respectively and slidably fixed on the first Z-axis motion module 3 and the second Z-axis motion module 10; the double-nozzle device comprises a high-temperature nozzle structure 4 and a normal-temperature nozzle structure 5 which are respectively fixed on a fixing plate 6; the double-nozzle device is slidably fixed on the X-axis movement module 1 through a fixing plate 6; and a printing platform 7 is arranged below the double-nozzle device, the printing platform 7 is slidably fixed on the Y-axis movement module 2, and the Y-axis movement module 2 is fixed on the base 8.
As shown in fig. 2 and 3, the X-axis movement module 1 includes an X-axis motor 101, an X-axis lead screw 104, and an X-axis fixing base 109 screwed on the X-axis lead screw 104, and the X-axis motor 101 and the X-axis lead screw 104 are connected by an X-axis coupler 103. The X-axis motion module 1 further comprises an X-axis slide rail 115 parallel to the X-axis lead screw 104; an X-axis slide block 116 which is slidably embedded outside the X-axis slide rail 115 is fixed on the X-axis fixing seat 109. The X-axis motor 101 drives the X-axis lead screw 104 to rotate, the X-axis lead screw 104 drives the X-axis fixing seat 109 to move, and due to the limiting effect of the X-axis sliding rail 115 and the X-axis sliding block 116, the X-axis fixing seat 109 can only reciprocate along the direction of the X-axis sliding rail 115. The double-nozzle device is fixed on the X-axis fixing seat 109 through the fixing plate 6, and the double-nozzle device can reciprocate along the X-axis direction under the driving of the X-axis movement module 1.
The X-axis motion module 1 further comprises an X-axis motor connecting piece 102 for fixing an X-axis motor 101, and an X-axis fixing end 105 and an X-axis supporting end 112 for fixing an X-axis lead screw 104; the X-axis fixed end 105 is fixed on the shell of the X-axis motion module 1 through an X-axis fixed end connecting piece 114; the X-axis support end 112 is secured to the housing of the X-axis motion module 1 by an X-axis support end connection 118. As shown in fig. 4, the X-axis fixed end connector 114 is provided with an X-axis limit switch 106 for limiting the displacement of the X-axis slider 116, the X-axis limit switch 106 is fixed on the X-axis limit switch connector 107, and the X-axis limit switch connector 107 is fixed on the X-axis fixed seat connector 114.
As shown in fig. 5 and 6, the dual spray head apparatus includes a high temperature spray head structure 4 and a normal temperature spray head structure 5. Wherein, high temperature nozzle structure 4 includes thermal insulation shell 403 and is located the inside detachable first syringe 401 of thermal insulation shell 403, and first syringe 401 is inside to hold the biological printing material. The top of the first syringe 401 is connected with a first adapter 402, the first adapter 402 is connected with an air cylinder through an air pipe, the bottom of the first syringe 401 is provided with a first nozzle 406, pressure is transmitted to the inside of the first syringe 401 through the air cylinder, and the biological printing material is ejected from the first nozzle 406 through pneumatic extrusion. The heat preservation shell 403 is provided with a first threaded hole 404, and the high-temperature nozzle structure 4 is fixed on the fixing plate 6 through the first threaded hole 404. The high-temperature spray head structure 4 can be fixed on the fixing plate 6 by screwing the bolt in the first threaded hole 404; when the bolt is unscrewed, the high-temperature spray head structure 4 can be detached and taken down.
As shown in fig. 7, the heat insulating case 403 is provided with through holes for mounting a heating element 901 and a thermal sensor 902. The heating element 901 is a heating rod, the thermal sensor 902 is a thermocouple, and the thermocouple is connected with the heat-insulating shell 403 and can monitor the temperature in the heat-insulating shell 403 in real time. When the temperature reaches the set value, the heating rod stops heating, and when the temperature deviates from the set value, the heating rod restarts heating. The heat preservation shell 403 is provided with a third threaded hole 405 and a fourth threaded hole 407, bolts are screwed into the third threaded hole 405 and the fourth threaded hole 407, and the heating rod and the thermal couple are fixed respectively by the cap peak of the two bolts to prevent falling off.
The normal temperature spray head structure 5 comprises a first fixing member 503, a second fixing member 504 and a second needle cylinder 501, the centers of the first fixing member 503 and the second fixing member 504 are provided with openings, and the second needle cylinder 501 is arranged in the openings of the first fixing member 503 and the second fixing member 504; the top of the second syringe 501 is connected with a second adapter 502, the second adapter 502 is connected with the air cylinder through an air pipe, the bottom of the second syringe 501 is provided with a second nozzle 506, pressure is transmitted to the inside of the second syringe 501 through the air cylinder, and the biological printing material is ejected from the second nozzle 506 through pneumatic extrusion. The first fixing member 503 is provided with a second screw hole 505, and the second cylinder 501 is fixed to the fixing plate 6 through the second screw hole 505. The second needle cylinder 501 can be fixed on the fixing plate 6 by screwing the bolt in the second threaded hole 505; when the bolt is unscrewed, the second cylinder 501 can be removed.
According to the double-nozzle structure, the high-temperature nozzle structure 4 has a heating and heat-insulating function, and can be used for printing melt extrusion biological materials with good supporting performance, such as pcl, pla and the like, which are used as materials of a supporting structure of a tissue engineering bracket; the normal temperature spray head structure 5 is used for printing normal temperature hydrogel, such as sodium alginate, hyaluronic acid and the like, and is formed by using the normal temperature hydrogel as a material of an active filler of a tissue engineering scaffold, and meanwhile, the structural design can reduce the mechanism load.
The device can be used for printing tissue engineering supports formed by two materials, the supporting structure and the active filler are respectively printed simultaneously, the defect that the three-dimensional printing forming performance of common hydrogel materials is poor is overcome, and the printing efficiency is improved.
The internal structures of the first Z-axis motion module 3, the second Z-axis motion module 10 and the Y-axis motion module 2 are the same as the internal structure of the X-axis motion module 1.
The first Z-axis movement module 3 comprises a first Z-axis motor, a first Z-axis screw rod and a first Z-axis fixing seat which is sleeved on the first Z-axis screw rod in a threaded manner, and the first Z-axis motor and the first Z-axis screw rod are connected through a first Z-axis coupler; the first Z-axis movement module also comprises a first Z-axis slide rail parallel to the first Z-axis screw rod; a first Z-axis sliding block which is embedded outside the first Z-axis sliding rail in a sliding manner is fixed on the first Z-axis fixing seat; one end of the shell of the X-axis motion module 1 is slidably fixed on the first Z-axis fixed seat; the first Z-axis motion module further comprises a first Z-axis motor connecting piece used for fixing a first Z-axis motor, a first Z-axis fixing end used for fixing a first Z-axis screw rod and a first Z-axis supporting end; the first Z-axis fixed end is fixed on the shell of the first Z-axis motion module through a first Z-axis fixed end connecting piece; a first Z-axis limit switch for limiting the displacement of the first Z-axis slide block is arranged on the first Z-axis fixed end connecting piece; the first Z-axis supporting end is fixed on a shell of the first Z-axis movement module through a first Z-axis supporting end connecting piece.
The second Z-axis movement module 10 comprises a second Z-axis motor, a second Z-axis screw rod and a second Z-axis fixing seat which is sleeved on the second Z-axis screw rod in a threaded manner, and the second Z-axis motor and the second Z-axis screw rod are connected through a second Z-axis coupler; the second Z-axis movement module also comprises a second Z-axis slide rail parallel to the second Z-axis screw rod; a second Z-axis sliding block which is embedded outside the second Z-axis sliding rail in a sliding manner is fixed on the second Z-axis fixing seat; one end of the shell of the X-axis motion module 1 is slidably fixed on the second Z-axis fixed seat; the second Z-axis motion module also comprises a second Z-axis motor connecting piece used for fixing a second Z-axis motor, a second Z-axis fixing end used for fixing a second Z-axis screw rod and a second Z-axis supporting end; the second Z-axis fixed end is fixed on the shell of the second Z-axis motion module through a second Z-axis fixed end connecting piece; a second Z-axis limit switch for limiting the displacement of the second Z-axis slide block is arranged on the second Z-axis fixed end connecting piece; and the second Z-axis supporting end is fixed on the shell of the second Z-axis motion module through a second Z-axis supporting end connecting piece.
First Z axle motor drive first Z axle lead screw rotates, and first Z axle lead screw drives first Z axle fixing base motion, because the limiting action of first Z axle slide rail and first Z axle slider, first Z axle fixing base can only be along first Z axle slide rail direction upward reciprocating motion. Similarly, the second Z-axis motor drives the second Z-axis screw rod to rotate, the second Z-axis screw rod drives the second Z-axis fixing seat to move, and due to the limiting effect of the second Z-axis sliding rail and the second Z-axis sliding block, the second Z-axis fixing seat can only reciprocate in the direction along the second Z-axis sliding rail. One end of the shell of the X-axis movement module 1 is slidably fixed on the first Z-axis fixing seat, the other end of the shell of the X-axis movement module 1 is slidably fixed on the second Z-axis fixing seat, and the X-axis movement module 1 can reciprocate along the Z-axis direction so as to adjust the position of the double-nozzle device in the Z-axis direction.
The Y-axis motion module 2 comprises a Y-axis motor, a Y-axis screw rod and a Y-axis fixed seat which is sleeved on the Y-axis screw rod in a threaded manner, and the Y-axis motor is connected with the Y-axis screw rod through a Y-axis coupler; the Y-axis motion module also comprises a Y-axis slide rail parallel to the Y-axis screw rod; a Y-axis sliding block which is embedded outside the Y-axis sliding rail in a sliding manner is fixed on the Y-axis fixing seat; the Y-axis motion module also comprises a Y-axis motor connecting piece for fixing a Y-axis motor, a Y-axis fixed end and a Y-axis supporting end for fixing a Y-axis screw rod; the Y-axis fixed end is fixed on the shell of the Y-axis motion module through a Y-axis fixed end connecting piece; a Y-axis limit switch for limiting the displacement of the Y-axis slide block is arranged on the Y-axis fixed end connecting piece; the Y-axis supporting end is fixed on the shell of the Y-axis movement module through a Y-axis supporting end connecting piece.
The Y-axis motor drives the Y-axis screw rod to rotate, the Y-axis screw rod drives the Y-axis fixing seat to move, and due to the limiting effect of the Y-axis sliding rail and the Y-axis sliding block, the Y-axis fixing seat can only reciprocate in the direction along the Y-axis sliding rail. The printing platform 7 can be fixed on the Y-axis fixing seat in a sliding mode, and the printing platform 7 can reciprocate along the Y-axis direction under the driving of the Y-axis moving module 2.
The utility model discloses a biological printing apparatus of 3D is applicable to multiple biomaterial, and application scope is extensive, if: tricalcium phosphate, titanium alloy, nacrum, hydroxyapatite and the like are used as bone tissue repair and regeneration materials; gelatin, alginate, fibrin, ossein, etc. used as soft tissue scaffold material; living cell materials for printing biological structures and organs, such as embryonic stem cells, adipose-derived stem cells, hepatic cells, mesenchymal stem cells and the like; polylactic acid, lactic acid-glycolic acid copolymer, polyhydroxyalkanoate and other materials for controllably releasing drugs; polyurethane, silicone, and the like are used as materials for medical aids. When printing living cell material, the suitable amount of culture solution is splendid attire in the open container of splendid attire culture solution, through the position of Y axle motion module regulation print platform, guarantees that the biomaterial that prints submerges in suitable culture solution to keep the biological activity of cell.
The utility model discloses a 3D biological printing apparatus's theory of operation and working process as follows:
(1) scanning and designing a three-dimensional solid model, and slicing the model by using upper computer processing software;
(2) selecting experimental materials, preparing a needed high-molecular biological material solution according to a proper proportion, and placing the solution in a double-nozzle device;
(3) inputting data information obtained by slicing into a first Z-axis motion module, a second Z-axis motion module, an X-axis motion module and a Y-axis motion module, further controlling the double-nozzle device to move in the X-axis and Z-axis directions, controlling the printing platform to move in the Y-axis direction, spraying the biological material liquid drops by the nozzle under the action of air pressure, printing the support structure by the high-temperature nozzle structure 4, and simultaneously printing active fillers by the normal-temperature nozzle structure 5; after the first layer is processed, the nozzle is lifted by one layer thickness, the second layer printing is carried out, and the layers are overlapped and formed layer by layer;
(4) the macromolecule solution sprayed out from the nozzle and the substrate solution in the printing area complete the curing process under the chemical crosslinking action.
Claims (10)
1. A portable 3D biological printing device, its characterized in that: comprises a base (8), a first Z-axis motion module (3), a second Z-axis motion module (10), an X-axis motion module (1), a double-nozzle device, a Y-axis motion module (2) and a printing platform (7); the first Z-axis movement module (3) and the second Z-axis movement module (10) are arranged in parallel and fixed on two opposite sides of the base (8); two ends of the X-axis movement module (1) are respectively and slidably fixed on the first Z-axis movement module (3) and the second Z-axis movement module (10); the double-nozzle device comprises a high-temperature nozzle structure (4) and a normal-temperature nozzle structure (5) which are respectively fixed on a fixing plate (6); the double-nozzle device is slidably fixed on the X-axis movement module (1) through a fixing plate (6); the printing platform (7) is located below the double-nozzle device and is slidably fixed on the Y-axis movement module (2), and the Y-axis movement module (2) is fixed on the base (8).
2. The portable 3D bioprinting device of claim 1, wherein: the X-axis movement module (1) comprises an X-axis motor (101), an X-axis screw rod (104) and an X-axis fixing seat (109) which is sleeved on the X-axis screw rod (104) in a threaded manner, and the X-axis motor (101) is connected with the X-axis screw rod (104) through an X-axis coupler (103);
the X-axis movement module (1) further comprises an X-axis slide rail (115) parallel to the X-axis screw rod (104); an X-axis sliding block (116) which is slidably embedded on an X-axis sliding rail (115) is fixed on the X-axis fixing seat (109);
the double-nozzle device is fixed on an X-axis fixing seat (109) through a fixing plate (6).
3. The portable 3D bioprinting device of claim 2, wherein: the X-axis movement module (1) further comprises an X-axis motor connecting piece (102) used for fixing an X-axis motor (101), an X-axis fixing end (105) used for fixing an X-axis lead screw (104) and an X-axis supporting end (112);
the X-axis fixed end (105) is fixed on the shell of the X-axis motion module (1) through an X-axis fixed end connecting piece (114); an X-axis limit switch (106) for limiting the displacement of the X-axis sliding block (116) is arranged on the X-axis fixed end connecting piece (114);
the X-axis supporting end (112) is fixed on a shell of the X-axis motion module (1) through an X-axis supporting end connecting piece (118).
4. The portable 3D bioprinting device of claim 1, wherein: the high-temperature spray head structure (4) comprises a heat-preservation shell (403) and a detachable first needle cylinder (401) positioned inside the heat-preservation shell (403); the top of the first needle cylinder (401) is connected with a first adapter (402), the first adapter (402) is connected with the air cylinder through an air pipe, and the bottom of the first needle cylinder (401) is provided with a first nozzle (406); a first threaded hole (404) is formed in the heat insulation shell (403), and the high-temperature spray head structure (4) is fixed on the fixing plate (6) through the first threaded hole (404).
5. The portable 3D bioprinting device of claim 4, wherein: a heating element (901) and a heat-sensitive sensor (902) are arranged in the heat-insulating shell (403).
6. The portable 3D bioprinting device of claim 5, wherein: the heating element (901) is a heating rod, and the heat-sensitive sensor (902) is a thermocouple.
7. The portable 3D bioprinting device of claim 1, wherein: the normal-temperature spray head structure (5) comprises a first fixing piece (503), a second fixing piece (504) and a second needle cylinder (501) positioned in the open holes of the first fixing piece (503) and the second fixing piece (504); the top of the second needle cylinder (501) is connected with a second adapter (502), the second adapter (502) is connected with the air cylinder through an air pipe, and the bottom of the second needle cylinder (501) is provided with a second nozzle (506); the first fixing piece (503) is provided with a second threaded hole (505), and the second needle cylinder (501) is fixed on the fixing plate (6) through the second threaded hole (505).
8. The portable 3D bioprinting device of claim 1, wherein: the first Z-axis movement module (3) comprises a first Z-axis motor, a first Z-axis screw rod and a first Z-axis fixing seat which is sleeved on the first Z-axis screw rod in a threaded manner, and the first Z-axis motor is connected with the first Z-axis screw rod through a first Z-axis coupler;
the first Z-axis movement module also comprises a first Z-axis slide rail parallel to the first Z-axis screw rod; a first Z-axis sliding block which is embedded outside the first Z-axis sliding rail in a sliding manner is fixed on the first Z-axis fixing seat; one end of the shell of the X-axis motion module is slidably fixed on the first Z-axis fixed seat;
the first Z-axis motion module further comprises a first Z-axis motor connecting piece used for fixing a first Z-axis motor, a first Z-axis fixing end used for fixing a first Z-axis screw rod and a first Z-axis supporting end;
the first Z-axis fixed end is fixed on the shell of the first Z-axis motion module through a first Z-axis fixed end connecting piece; a first Z-axis limit switch for limiting the displacement of the first Z-axis slide block is arranged on the first Z-axis fixed end connecting piece;
the first Z-axis supporting end is fixed on a shell of the first Z-axis movement module through a first Z-axis supporting end connecting piece.
9. The portable 3D bioprinting device of claim 1, wherein: the second Z-axis movement module (10) comprises a second Z-axis motor, a second Z-axis screw rod and a second Z-axis fixing seat which is sleeved on the second Z-axis screw rod in a threaded manner, and the second Z-axis motor is connected with the second Z-axis screw rod through a second Z-axis coupler;
the second Z-axis motion module also comprises a second Z-axis slide rail parallel to the second Z-axis screw rod; a second Z-axis sliding block which is embedded outside the second Z-axis sliding rail in a sliding manner is fixed on the second Z-axis fixing seat; one end of the shell of the X-axis motion module is slidably fixed on the second Z-axis fixed seat;
the second Z-axis motion module also comprises a second Z-axis motor connecting piece used for fixing a second Z-axis motor, a second Z-axis fixing end used for fixing a second Z-axis screw rod and a second Z-axis supporting end;
the second Z-axis fixed end is fixed on the shell of the second Z-axis motion module through a second Z-axis fixed end connecting piece; a second Z-axis limit switch for limiting the displacement of the second Z-axis slide block is arranged on the second Z-axis fixed end connecting piece;
and the second Z-axis supporting end is fixed on the shell of the second Z-axis movement module through a second Z-axis supporting end connecting piece.
10. The portable 3D bioprinting device of claim 1, wherein: the Y-axis movement module (2) comprises a Y-axis motor, a Y-axis screw rod and a Y-axis fixing seat which is sleeved on the Y-axis screw rod in a threaded manner, and the Y-axis motor is connected with the Y-axis screw rod through a Y-axis coupler;
the Y-axis motion module also comprises a Y-axis slide rail parallel to the Y-axis screw rod; a Y-axis sliding block which is embedded outside the Y-axis sliding rail in a sliding manner is fixed on the Y-axis fixing seat; the printing platform is slidably fixed on the Y-axis fixing seat;
the Y-axis motion module also comprises a Y-axis motor connecting piece for fixing a Y-axis motor, a Y-axis fixed end and a Y-axis supporting end for fixing a Y-axis screw rod;
the Y-axis fixed end is fixed on the shell of the Y-axis movement module through a Y-axis fixed end connecting piece; a Y-axis limit switch for limiting the displacement of the Y-axis slide block is arranged on the Y-axis fixed end connecting piece;
and the Y-axis supporting end is fixed on the shell of the Y-axis movement module through a Y-axis supporting end connecting piece.
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|---|---|---|---|
| CN201920638703.5U CN210026313U (en) | 2019-05-07 | 2019-05-07 | Portable 3D biological printing equipment |
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| CN201920638703.5U CN210026313U (en) | 2019-05-07 | 2019-05-07 | Portable 3D biological printing equipment |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111357787A (en) * | 2020-04-01 | 2020-07-03 | 西京学院 | Cake pattern-mounting 3D printing system |
| CN112026164A (en) * | 2020-08-17 | 2020-12-04 | 西安交通大学 | Double-nozzle hybrid continuous fiber reinforced composite material 3D printing device and method |
| CN113059190A (en) * | 2021-03-12 | 2021-07-02 | 哈尔滨工业大学 | Liquid metal microscale 4D printer |
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2019
- 2019-05-07 CN CN201920638703.5U patent/CN210026313U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111357787A (en) * | 2020-04-01 | 2020-07-03 | 西京学院 | Cake pattern-mounting 3D printing system |
| CN112026164A (en) * | 2020-08-17 | 2020-12-04 | 西安交通大学 | Double-nozzle hybrid continuous fiber reinforced composite material 3D printing device and method |
| CN112026164B (en) * | 2020-08-17 | 2021-10-19 | 西安交通大学 | Double-nozzle hybrid continuous fiber reinforced composite material 3D printing device and method |
| CN113059190A (en) * | 2021-03-12 | 2021-07-02 | 哈尔滨工业大学 | Liquid metal microscale 4D printer |
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Effective date of registration: 20210608 Address after: 264200 4th floor, zone J, Donglan entrepreneurial Valley, Binhai Road North, Longhai Road, Nanhai New District, Weihai City, Shandong Province Patentee after: Shandong Bering 3D Technology Co.,Ltd. Address before: No. 122, Ninghai Road, Gulou District, Nanjing, Jiangsu 210023 Patentee before: NANJING NORMAL University |