CN210006692U - Ion source imaging device - Google Patents
Ion source imaging device Download PDFInfo
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- CN210006692U CN210006692U CN201920895259.5U CN201920895259U CN210006692U CN 210006692 U CN210006692 U CN 210006692U CN 201920895259 U CN201920895259 U CN 201920895259U CN 210006692 U CN210006692 U CN 210006692U
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Abstract
The utility model discloses an ion source imaging device, this ion source imaging device includes the ion source cavity, the ion source adds electrical module, the speculum, the printing opacity sealing member, imaging lens, camera lens support piece and image acquisition mechanism, the ion source cavity has sample window and light reflection window, the ion source adds electrical module and establishes in the ion source cavity and be close to in the sample window, the sealed light reflection window of printing opacity sealing member, camera lens support piece is located the outside of ion source cavity and connects the ion source cavity, camera lens support piece has reflection channel, reflection channel's end is relative with the sample window, imaging lens and camera lens support piece rotatable coupling just communicate with each other with reflection channel's end in addition, image acquisition mechanism is connected with imaging lens, all be equipped with the speculum in the ion source cavity and the reflection channel, the speculum in the ion source cavity, the speculum in the reflection channel can be with the image transmission of target plate to imaging lens in this ion source imaging device simple structure.
Description
Technical Field
The utility model relates to a detection area especially relates to kinds of ion source image device.
Background
The matrix assisted laser desorption ionization time-of-flight mass spectrometer is type of biological mass spectrometer commonly used for macromolecular sample analysis, when a sample is analyzed, the sample is usually formed into a solid on a sample target, and then the sample target in a sample introduction chamber is conveyed to a moving platform in a vacuum state through a lifting device, an electric field generated by combining a pole piece and an electric system is utilized to accelerate, focus and deflect ions with initial dispersion into a field-free flight area, and the ions with different masses are separated and then are sequentially conveyed into a detector for detection.
SUMMERY OF THE UTILITY MODEL
Based on this, there is a need to provide kinds of ion source imaging devices with simple structure, small size, convenient adjustment and improved imaging effect.
ion source imaging device, including ion source cavity, ion source power module, speculum, printing opacity sealing member, imaging lens, camera lens support piece and image acquisition mechanism, the ion source cavity has sample window and light reflection window, the ion source power module is established in the ion source cavity and be close to in the sample window, the printing opacity sealing member is installed in the light reflection window with sealed the light reflection window, camera lens support piece is located the outside of ion source cavity and connect the ion source cavity, camera lens support piece has reflection channel, reflection channel's end with the sample window is relative, imaging lens with camera lens support piece rotatable coupling and with reflection channel's end communicates with each other in addition, image acquisition mechanism with imaging lens connects, all be equipped with in the ion source cavity and in the reflection channel the speculum, in the ion source cavity the speculum, the speculum in the reflection channel can transmit the image of sample window department to in the imaging lens.
In embodiments, the reflection channel is bent at a right angle, and the reflector in the reflection channel is used for reflecting light from the reflector in the ion source cavity into the imaging lens at a right angle.
In of these embodiments, the mirrors in the reflective channel are disposed at the right-angled corners of the reflective channel.
In embodiments, the ion source imaging apparatus further comprises a mirror holder, the lens holder has a holder channel in communication with the reflection channel, the mirror holder has a placement platform for placing a mirror, the mirror platform extends into the reflection channel through the holder channel, and the mirror holder is connected to the lens holder.
In of these embodiments, the mirror mount is removably connected to the lens holder.
In embodiments, the ion source imaging apparatus further comprises a screw, and the mirror holder and the lens holder are detachably connected by the screw.
In embodiments, the ion source imaging device further comprises a lens nut, the lens support piece has a boss towards the end of the imaging lens, the outer peripheral wall of the boss has threads, the outer peripheral wall of the imaging lens towards the end of the lens support piece has threads, the imaging lens abuts against the boss, and the lens nut is in threaded connection with the imaging lens and the lens support piece to realize the connection of the imaging lens and the lens support piece.
In of these embodiments, the image acquisition mechanism is an industrial camera.
In of these embodiments, the mirror is a right triangular prism.
In of these embodiments, the image acquisition mechanism is threadably connected to the imaging lens.
The imaging light path device of the ion source imaging device has the advantages of simple structure, small volume, convenience in adjustment and capability of quickly, accurately and clearly displaying a sample target point so as to improve the imaging effect, in the testing process, the sample point on the target plate can be reflected to the imaging lens through the two reflectors and then is acquired by the image acquisition mechanism, so that the actual condition of the sample target point on the target plate can be checked on a computer display screen.
The ion source imaging device is provided with the reflection channel which is bent at a right angle, and the reflection mirror in the reflection channel is used for reflecting light rays from the reflection mirror in the ion source cavity to the imaging lens at a right angle, so that the size of the whole ion source imaging device can be reduced.
When the position of the industrial camera is found to deviate from the set position in the test process, the lens nut can be loosened, the image acquisition mechanism is adjusted to the set position, and then the lens nut is screwed, so that the ion source imaging device is convenient to operate, can ensure that the image acquisition mechanism is fixed at will within the range of 360 degrees, and improves the imaging effect of a target point.
The distance between the right-angle triple prism as the reflector and the sample target point on the imaging lens and the target plate is short, the right-angle triple prism is not easy to deform and high in reflectivity, and the imaging effect can be improved.
Drawings
FIG. 1 is a schematic side view of an ion source imaging apparatus according to an embodiment ;
FIG. 2 is a schematic diagram of the ion source imaging apparatus shown in FIG. 1;
FIG. 3 is a schematic side view of the ion source imaging apparatus shown in FIG. 2;
fig. 4 is a crystallographic image of an ACTH sample taken with a conventional imaging device;
FIG. 5 is a crystal mapping image of a SNP site gene sample obtained by a conventional imaging apparatus;
fig. 6 is a crystal image of the ACTH sample obtained by the ion source imaging apparatus shown in fig. 1;
FIG. 7 is a crystal image of the SNP locus gene sample obtained by the ion source imaging apparatus shown in FIG. 1.
Description of the reference numerals
10: an ion source imaging device; 100: an ion source cavity; 110: a sample window; 120: a light reflective window; 200: an ion source power-up module; 300: a mirror; 400: a light transmissive seal; 500: an imaging lens; 600: a lens support; 610: a reflection channel; 620: a boss; 700: an image acquisition mechanism; 800: a reflector fixing member; 900: a lens nut; 20: and (4) a target plate.
Detailed Description
In order to facilitate understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. The preferred embodiments of the present invention are shown in the drawings. The invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It is noted that when an element is referred to as being "secured to" another elements, it may be directly secured to another elements or intervening elements may be present as well. 0 elements are referred to as being "coupled" to another elements, it may be directly coupled to another elements or intervening elements may be present at the same time. elements are referred to as being "mounted" to another elements, it may be directly mounted to another elements or intervening elements may be present at the same time. elements are referred to as being "disposed" to another elements, it may be directly disposed to another elements or intervening elements may be present at the same time.
The terminology used herein in the description of the present invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention, the terminology used herein "and/or" includes any and all combinations of or more of the associated listed items.
Referring to fig. 1, an embodiment of the present invention provides ion source imaging apparatus 10, which includes an ion source chamber 100, an ion source power-up module 200, a mirror 300, a transparent sealing member 400, an imaging lens 500, a lens support 600, and an image capturing mechanism 700.
The ion source cavity 100 has a sample window 110 and a light reflection window 120, wherein, referring to fig. 1 and 2, the sample window 110 is located on the bottom surface of the ion source cavity 100, and the light reflection window 120 is located on the side surface of the ion source cavity 100. The outer portion of the sample window 110 is used to place the target plate 20. An ion source power-up module 200 is disposed within the ion source chamber 100 and proximate to the sample window 110, the ion source power-up module 200 being configured to accelerate the sample from the target plate 20.
The light transmissive sealing member 400 is installed in the light reflective window 120 to seal the light reflective window 120. The light transmissive sealing member 400 serves to seal the light reflective window 120.
The lens holder 600 is disposed outside the ion source chamber 100 and connected to the ion source chamber 100, the lens holder 600 has a reflection channel 610, an end of the reflection channel 610 is opposite to the sample window 110, and the imaging lens 500 is rotatably connected to the lens holder 600 and communicates with the other end of the reflection channel 610.
Preferably, the reflective channel 610 is bent at a right angle. The mirror 300 in the reflection channel 610 is used to reflect light from the mirror 300 in the ion source cavity 100 into the imaging lens 500 at a right angle. The ion source imaging device 10 is provided with the reflection channel 610 bent at a right angle, as shown in fig. 1 and fig. 3, the reflector 300 in the reflection channel 610 is used for reflecting the light from the reflector 300 in the ion source cavity 100 into the imaging lens 500 at a right angle, so that the volume of the whole ion source imaging device 10 can be reduced. The arrangement enables the imaging lens 500 to be tightly attached to the outer wall of the ion source cavity 100, so that the size of the whole ion source imaging device 10 is reduced, the reflection channel 610 bent at a right angle can also shorten the light reflection distance, and the imaging quality is improved.
, the reflector 300 in the reflective channel 610 is disposed at the right-angle corner of the reflective channel 610, so that the reflector 300 is disposed at an angle of 45 °, and the light at the end of the reflective channel 610 bent at a right angle can be reflected to the other end , that is, the light on the reflector 300 in the ion source cavity 100 is reflected at a right angle to the imaging lens 500, so as to achieve the right-angle bending reflection of the light.
, the ion source imaging apparatus 10 further comprises a mirror mount 800. the lens holder 600 has a holder channel in communication with the mirror channel 610. the mirror mount 800 has a placement platform for placing the mirror 300. the mirror 300 platform extends into the mirror channel 610 through the holder channel, and the mirror mount 800 is connected to the lens holder 600.
Alternatively, the mirror holder 800 is detachably coupled to the lens holder 600.
, the ion source imaging apparatus 10 further comprises a screw, the mirror mount 800 is detachably connected to the lens holder 600 by the screw, specifically, the mirror mount 800 and the lens holder 600 are both provided with a threaded hole, the screw is provided with an external thread, and the screw is inserted into the threaded hole of the mirror mount 800 and the lens holder 600 to fix the mirror mount 800 and the lens holder 600.
In embodiments, the ion source imaging device 10 further includes a lens nut 900, the end of the lens holder 600 facing the imaging lens 500 has a boss 620, the outer peripheral wall of the boss 620 has threads, the outer peripheral wall of the end of the imaging lens 500 facing the lens holder 600 has threads, the imaging lens 500 abuts against the boss 620, the lens nut 900 is in threaded connection with the imaging lens 500 and the lens holder 600 to achieve connection between the imaging lens 500 and the lens holder 600. the ion source imaging device 10 is provided with the lens nut 900, the imaging lens 500 and the image capturing mechanism 700 are connected together at during installation, the imaging lens 500 and the lens holder 600 are connected to ensure that the position of the image capturing mechanism 700 is in a required direction, and then the lens nut 900 can be screwed, when the industrial camera position is found to be deviated from a set position during testing, the lens nut 900 can be unscrewed and then the image capturing mechanism 700 can be adjusted to the set position and then the lens nut 900 is screwed, so as to facilitate operation, and at the same time, the image capturing mechanism 700 can be fixed arbitrarily within a range of 360 degrees, and improve the imaging effect of.
In of these embodiments, image acquisition mechanism 700 is an industrial camera.
In embodiments, the reflector 300 is a right-angled triple prism, the size of the reflector 300 sheet of the right-angled triple prism is 10mm × 10mm, the ion source imaging device 10 is provided with the right-angled triple prism as the reflector 300, and the distance between the imaging lens 500 and the sample target point on the target plate 20 is short, so that the imaging effect can be improved because the right-angled triple prism is not easy to deform and has high reflectivity.
In embodiments, image capture mechanism 700 is threadably coupled to imaging lens 500, and so configured, the stability of the coupling of image capture mechanism 700 to imaging lens 500 can be achieved.
The utility model discloses an ion source imaging device 10 when the installation, image acquisition mechanism 700 is connected with wherein angles and imaging lens 500 after, image acquisition mechanism 700 may be in predetermined angle not accurately, only need adjust the position between imaging lens 500 and the lens support piece 600 this moment, can realize through rotating imaging lens 500 that image acquisition mechanism 700 reaches predetermined angle, perhaps in order not hard up through rotating lens nut 900, loosen between lens support piece 600 and the imaging lens 500, it also can realize that image acquisition mechanism 700 is in predetermined position to rotate imaging lens 500, rethread tight lens nut 900 realizes fixing between lens support piece 600 and the imaging lens 500 soon, and the regulation is convenient when saving, festival power, improve the imaging effect.
Comparative example 1
This comparative example was based on the above examples and each of the mirrors 300 was replaced with a thin mirror having dimensions of 10mm × 10mm × 0.5 mm. An image of a crystal obtained when a rectangular prism having a size of 10mm × 10mm × 10mm is used as the mirror 300 is shown in fig. 4, wherein fig. 4 is an image of an ACTH sample crystal in fig. 4 and 5, and fig. 5 is an image of a SNP site gene sample crystal. The crystal patterns obtained when the mirror 300 is a rectangular prism having a size of 10mm × 10mm × 0.5mm are shown in fig. 6 and 7, in which the left side in fig. 6 is the crystal pattern of the ACTH sample, and fig. 7 is the crystal pattern of the SNP site gene sample. As can be seen from comparison of fig. 4 and 6 and comparison of fig. 5 and 7, the crystal imaging effect of the ion source imaging apparatus 10 using the right-angled triple prism as the reflector is significantly better than that of the conventional thin reflector.
The imaging light path device of the ion source imaging device 10 has the advantages of simple structure, small volume, convenience in adjustment and capability of rapidly, accurately and clearly displaying a sample target point so as to improve the imaging effect, in the testing process, the sample point on the target plate 20 can be reflected to the imaging lens 500 through the two reflectors 300 and then is acquired by the image acquisition mechanism 700, so that the actual situation of the sample target point on the target plate 20 can be checked on a computer display screen.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.
Claims (10)
1, kind of ion source imaging device, its characterized in that, including ion source cavity, ion source power module, speculum, printing opacity sealing member, imaging lens, camera lens support piece and image acquisition mechanism, the ion source cavity has sample window and light reflection window, the ion source power module is established in the ion source cavity and be close to in the sample window, the printing opacity sealing member is installed in the light reflection window in order to seal the light reflection window, camera lens support piece is located the outside of ion source cavity and connect the ion source cavity, camera lens support piece has reflection channel, reflection channel's end with the sample window is relative, imaging lens with camera lens support piece rotatable coupling and with reflection channel's another end communicates with each other, image acquisition mechanism with imaging lens connects, in the ion source cavity and all be equipped with in the reflection channel the speculum, in the ion source cavity the speculum in the reflection channel can with the image transmission of sample window department extremely in the imaging lens.
2. The ion source imaging device of claim 1, wherein the reflection channel is bent at a right angle, and a mirror in the reflection channel is used for reflecting light from the mirror in the ion source cavity into the imaging lens at a right angle.
3. The ion source imaging apparatus of claim 1, wherein the mirrors in the reflection channel are disposed at right-angled corners of the reflection channel.
4. The ion source imaging apparatus of claim 3, further comprising a mirror mount, wherein the lens support has a support channel in communication with the reflection channel, wherein the mirror mount has a placement platform for placing a mirror, wherein the mirror platform extends into the reflection channel through the support channel, and wherein the mirror mount is coupled to the lens support.
5. The ion source imaging apparatus of claim 4, wherein the mirror mount is removably coupled to the lens support.
6. The ion source imaging device of claim 5, further comprising a screw, wherein the mirror holder and the lens holder are detachably connected by the screw.
7. The ion source imaging device according to any of claims 1-6, further comprising a lens nut, wherein the lens support has a boss towards the end of the imaging lens, the outer periphery of the boss has threads, the outer periphery of the imaging lens towards the end of the lens support has threads, the imaging lens abuts the boss, and the threaded connection of the lens nut with the imaging lens and the lens support enables the imaging lens to be connected with the lens support.
8. The ion source imaging device of any of , wherein the image capture mechanism is an industrial camera.
9. The ion source imaging device of any of , wherein the mirror is a right triangular prism.
10. The ion source imaging device according to any of of claims 1-6, wherein the image capture mechanism is threadably connected to the imaging lens.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920895259.5U CN210006692U (en) | 2019-06-14 | 2019-06-14 | Ion source imaging device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920895259.5U CN210006692U (en) | 2019-06-14 | 2019-06-14 | Ion source imaging device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210006692U true CN210006692U (en) | 2020-01-31 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201920895259.5U Active CN210006692U (en) | 2019-06-14 | 2019-06-14 | Ion source imaging device |
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| CN (1) | CN210006692U (en) |
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| CP02 | Change in the address of a patent holder |
Address after: 510535 building 501, No. 1, No. 16, Xinrui Road, Huangpu District, Guangzhou, Guangdong Province (office only) Patentee after: GUANGZHOU HEXIN KANGYUAN MEDICAL TECHNOLOGY CO.,LTD. Address before: 510700 3 / F, building A3, science and technology enterprise accelerator, 11 Kaiyuan Avenue, Huangpu District, Guangzhou City, Guangdong Province Patentee before: GUANGZHOU HEXIN KANGYUAN MEDICAL TECHNOLOGY CO.,LTD. |
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| CP02 | Change in the address of a patent holder |