CN2099763U - Air-lift type fermentation reactor - Google Patents
Air-lift type fermentation reactor Download PDFInfo
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- CN2099763U CN2099763U CN 91226248 CN91226248U CN2099763U CN 2099763 U CN2099763 U CN 2099763U CN 91226248 CN91226248 CN 91226248 CN 91226248 U CN91226248 U CN 91226248U CN 2099763 U CN2099763 U CN 2099763U
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- guide shell
- gas
- fermentation
- tank body
- multistage
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
- C12M29/08—Air lift
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/02—Means for regulation, monitoring, measurement or control, e.g. flow regulation of foam
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Abstract
The utility model relates to an air-lift type fermentation reactor, particularly an air-lift type fermentation reactor with the interior circulation type structure. The utility model comprises a skirt support (1), an upper and a lower sealing heads (2), (3), an air distribution tube (4), a sieve plate (5), a center guide shell (6), a multistage guide shell (7), a defrother (8) and a fermentation tank (9), wherein, the sieve plate (5) is welded on the center guide shell (6), and the multistage guide shell (7) is welded with the external periphery of the sieve plate (5). The integration which is composed of the sieve plate (5), the center guide shell (6) and the multistage guide shell (7) is installed in the fermentation tank (9), and the multistage guide shell (7) is welded with the fermentation tank (9). The structure lengthens the time of the contact of the air and the liquid, sufficiently dissolves the oxygen, provides sufficient oxygen for the fermentation, raises the productive rate and the extracting yielding rate and decreases the energy consumption through the multistage minor cycle circulation. The utility model is suitable for the production of fermented products such as amino acid, enzyme preparation, antibiotics, etc.
Description
The utility model relates to a kind of gas-lift fermentation reactor, particularly adopts the gas-lift fermentation reactor of internal-circulation type structure.
Fermentor tank is the nucleus equipment during fermentation industry is produced, leavened prod (as amino acid) is the microorganism in nutritive substance (as Glucose Liquid etc.) of certain species, absorb nutriment and be dissolved in oxygen in the nutritive medium, growth also transforms nutritive ingredient and metabolism goes out the product of (or thalline itself is exactly a product), and fermentor tank provides one to guarantee the nutritive medium oxygen supply and be beneficial to microorganism growth and product generates and metabolic production environment for this production process exactly.
What generally adopt in the domestic and international fermentative production at present, is mechanical agitator tank.This jar principle of work is: the fermented nutritive liquid of packing into earlier in fermentation, disinfection then, treat to insert under the proper temperature organism of fermentation bacterial classification, in the ventilation of fermentor tank bottom, by many grades of mechanical stirring, make gas-liquid mixed,, make it the growth and breeding metabolism for the microorganism in the nutritive medium provides oxygen, produce product, the shortcoming of this fermentation reactor is: efficient is low, the energy consumption height, and the production noise pollution is serious, the stirring rake of fermentor tank is strong to the mechanical shearing effect of microorganism, the vitality of microbial cells is reduced, and the bacterial chip of smashing forms protein-colloid in fermented nutritive liquid, be unfavorable for the subsequent extracted processing.
Gas-lift fermentation reactor is the novel fermentation reactor of introducing from Chemical Manufacture in the fermentative production, and the gas-lift fermentation reactor of research is only limited to two kinds of base types at present both at home and abroad: internal-circulation type and outer circulation type.Basic functional principle is: be example with the internal-circulation type, utilize the buoyancy lift of gas in liquid, feed gas at reactor bottom, promoting liquid with the buoyancy lift of gas rises and forms circulating up and down, at round-robin simultaneously, bubble in liquid stirring and sieve plate to the continuous fragmentation of bubble, replaced the mechanical agitation in mechanical jar, oxygen in the gas is dissolved in the liquid fully, satisfies the mass transfer between fermentation oxygen supply and solid-liquid.Internal-circulation type structure such as accompanying drawing 4, its major parts: aeration jet (21), gas-liquid rising area circulating barrel (22), fermentation tank body (23), jacket heat exchanger (24), opening for feed (25), discharge gate (26).Because this gas-lift fermentation reactor gas-to-liquid contact weak effect, mix fully inadequately, make the dissolved oxygen in the fermented liquid fail to guarantee effectively microorganism growth and the metabolic requirement of product, thereby cause product productive rate and extract yield low.
The purpose of this utility model provides a kind of product productive rate and extract yield height and the low fermentation reactor of energy consumption, and this reactor is a microorganism growth, and growth and product metabolism provide better environment.
Technical solution of the present utility model: a kind of gas-lift fermentation reactor is characterized in that this reactor comprises: skirt (1), upper and lower end socket (2), (3), gas distribution tube (4), sieve plate (5), central draft tube (6), multistage guide shell (7), froth breaker (8), fermentation tank body (9).Wherein, a plurality of annular sieve plates (5) overlapped central draft tube (6) and were cemented on the central draft tube (6); Central draft tube (6) is arranged in the multistage guide shell (7), multistage guide shell (7) inwall and annular sieve plate (5) outward flange concrete mutually; The integral body that sieve plate (5), central draft tube (6), multistage guide shell (7) are formed is arranged in the fermentation tank body (9); Multistage guide shell (7) has a plurality of fluid import and exports and takes over (10), (11), and a plurality of fluid import and exports are taken over (10), (11) are passed corresponding hole on the tank body, and are consolidated; Fixed fermentation tank body (9) bottom that is installed in of gas distribution tube (4); Have respectively into, fixed being installed on the fermentation tank body (9) of last lower cover of discharge gate (12), (13), and upper and lower the shutting of tank body (9) of will fermenting; Skirt (1) is cemented on the lower cover (2).The fluid import and export is taken over the overcoat (15) of (10), (11) to multistage guide shell (7), the interior cover of water coolant flow deflector (16) (17) is formed by having.Wherein, the water coolant flow deflector be spirally wrapped around that interior cover (17) is gone up and with interior cover (17) concrete mutually, overcoat (15) gap is enclosed within outside the flow deflector, interior cover and the overcoat two ends are fixed shuts.Sieve plate (5) by orifice plate (20), intersection is given distribution gusset (18), clean-out cover (19) is formed.Wherein, intersection is given distribution gusset (18) and orifice plate (20) concrete mutually; Orifice plate (20) has a manhole ringwise on the anchor ring; Manhole plate (19) covers on manhole and with orifice plate (20) fixedlys connected; All have many identical gas-liquid distribution holes on manhole plate (19) and the orifice plate (20).
The principle of work of this reactor: in fermentation reactor as shown in Figure 1, the fermented liquid (liquid amount is the 60-80% of fermentation reactor volume) of packing into, gas sprays into fermentation reactor from the gas distribution tube (4) of tower body, and the gas-liquid mixture fluid mobile in the reactor distributes as shown in Figure 5.The Ar district is a gas-liquid rising yield zone, the Acd district is decline race way, center, the Amd district is a multistage circulation decline yield zone, gas liquid mixture is under the effect of the unsteady lift of gas, rise along the Ar district, and by the further bubble crushing of gas-liquid distribution sieve plate, strengthen the gas-to-liquid contact area, strengthen gas-liquid mass transfer, form the multichannel circulation by multistage decline race way Amd then, make gas-liquid mass transfer even, the gas liquid mixture on tower top makes the material physico-chemical property balance as far as possible at the bottom of cat head and the tower at the bottom of decline race way, center Acd is recycled to tower.And created the outside atmosphere that a kind of periodic pressure changes for thalline, very help the metabolism of product.
The utility model stirs with existing mechanical and trembles its advantage of fermentor tank comparison and be:
1. solution-air and liquid-solid (thalli granule) mass transfer effect are good, can satisfy the requirement of various fermentation 1 processes (L-glutamic acid, citric acid, Methionin, SCP, the fermentative production of vitamins C and other amino acid or medical biochemical products).
2. cancelled mechanical stirring, eliminated the shear fracture effect of stirring to thalline, strengthened the vigor of thalline widely, created good condition for adopting new zymotechnique (adding fermentation operation) as feed supplement or stream, the production potential of thalline are not fully exerted, and product significantly improves (be example with L-glutamic acid, glucose acid invert ratio improves 10%-15%) to the productive rate of raw material, because the bacterial chip and the albumen colloid that do not have bacterial cell disruption to produce are very favourable to the back leaching process of product.
3. the energy consumption of fermenting process descends (be example with L-glutamic acid, produce ton L-glutamic acid energy loss-rate machinery jar decline 30-40%) significantly, has eliminated the noise pollution of production process, has greatly improved workman's operating environment.
4. utilized multistage water conservancy diversion circulation tube as interchanger, make heat interchanging area than common chuck, interchanger doubles, the ratio of heat interchanging area/fermentating liquid volume is improved greatly (reaching 1.6-4), and this ratio of common mechanical jar has only 1-1.2, improved the exchange capability of heat of fermentor tank greatly, can control the temperature variation of fermentation reactor rapidly and effectively, fermentation is carried out according to optimum process controling condition, cooling water is greatly saved, for good condition has been created in microbial growth and product metabolism.
5. fermentation reactor is simple to operate, and is easy to use.
6. remarkable in economical benefits.Regularity according to fermentative production can be known by inference, and the present invention not only can be used for glutamic acid fermentation, and can be used for citric acid, other amino acid, zymin, single cell protein, the production of leavened prods such as microbiotic, at present, Xinjiang molasses comprehensive utilization demonstration plant has adopted the present invention to manufacture and design 50m
2One of gas lift double loop glutamic acid fermentation reactor, Gansu Province also adopts in quintar sugar refinery the present invention to manufacture and design 75m
2Two of gas lift double loop glutamic acid fermentation reactors.
The utility model with existing its advantage of gas-lift fermentation reactor comparison is:
1, owing to adopt the structure of multistage guide shell, by the circulation of multistage minor cycle, strengthen the gas-liquid internal circulating load, particularly the bubble during liquid return is carried secretly, makes the gas-liquid contact time lengthening, and oxygen dissolution is abundant, fermentation oxygen supply abundance; Cancelled mechanical stirring, thoroughly eliminated production noise and stirring rake, the vigor of thalline is strengthened greatly the shear fracture of thalline.
2, owing to adopt the helical flow jacketed pipe heat exchanger and make it and integrate with the multistage water conservancy diversion circulating barrel of fermentation reactor (see in the accompanying drawing 1 7), making heat interchanging area is the twice of common chuck interchanger (single face heat exchange).
Accompanying drawing 1 is a front view of the present utility model.
Accompanying drawing 2 is the structure iron of multistage guide shell.
Accompanying drawing 3 is the structure iron of sieve plate.
Below in conjunction with description of drawings:
A kind of gas-lift fermentation reactor, it is characterized in that this reactor includes: skirt (1), upper and lower end socket (2), (3), gas distribution tube (4), sieve plate (5), central draft tube (6), multistage guide shell (7), froth breaker (8), fermentation tank body (9).Wherein, a plurality of annular sieve plates (5) overlapped central draft tube (6) and were welded on the central draft tube (6); Central draft tube (6) is arranged in the multistage guide shell (7), and multistage guide shell (7) inwall welds mutually with annular sieve plate (5) outward flange; The integral body that sieve plate (5), central draft tube (6), multistage guide shell (7) are formed is arranged in the fermentation tank body (9); Multistage guide shell (7) has the fluid import and export and takes over (10), (11), and a plurality of fluid import and exports are taken over (10), (11) are passed corresponding hole on the tank body, and welded together; The integral body that sieve plate (5), central draft tube (6), multistage guide shell (7) are formed welds together by fixed supported slab (14) and fermentation tank body (9); Gas distribution tube (4) welded and installed is in fermentation tank body (9) bottom; Have respectively into, the upper and lower end socket (2) of (12) of discharge gate, (13), (3) welded and installed on fermentation tank body (9), and upper and lower the shutting of tank body (9) of will fermenting; Skirt (1) is welded on the lower cover (2).Multistage guide shell (7) is made up of the overcoat (15) that has fluid import and export pipe (10), (11), water coolant flow deflector (16), interior cover (17).Wherein, the water coolant flow deflector is spirally wrapped around interior cover (17) and goes up and weld mutually with interior cover (17), and overcoat (15) gap is enclosed within outside the flow deflector, and interior cover and the welding of overcoat two ends are shut.Sieve plate (5) by orifice plate (20), intersection is given distribution gusset (18), manhole plate (19) is formed.Wherein, it is integrally welded with orifice plate (20) that intersection is given distribution gusset (18); Orifice plate (20) has a manhole ringwise on the anchor ring; Manhole plate (19) covers on manhole and with orifice plate (20) screw and is connected; All have many identical gas-liquid distribution holes on manhole plate (19) and the orifice plate (20).
Claims (3)
1, a kind of gas-lift fermentation reactor is characterized in that this reactor includes: skirt (1), upper and lower end socket (2), (3), gas distribution tube (4), sieve plate (5), central draft tube (6), multistage guide shell (7), froth breaker (8), fermentation tank body (9); Wherein, a plurality of annular sieve plates (5) overlapped central draft tube (6) and were cemented on the central draft tube (6); Central draft tube (6) is arranged in the multistage guide shell (7), multistage guide shell (7) inwall and annular sieve plate (5) outward flange concrete mutually; The integral body that sieve plate (5), central draft tube (6), multistage guide shell (7) are formed is arranged in the fermentation tank body (9); Multistage guide shell (7) has a plurality of fluid inlet and outlets and takes over (10), (11), and a plurality of fluid inlet and outlets are taken over (10), (11) are passed corresponding hole on the tank body, and are consolidated; Fixed fermentation tank body (9) bottom that is installed in of gas distribution tube (4); Have respectively into, fixed being installed on the fermentation tank body (9) of last lower cover of discharge gate (12), (13), and the tank body (9) that will ferment is shut up and down; Skirt (1) is cemented on the lower cover (2),
2, gas-lift fermentation reactor according to claim 1 is characterized in that: the fluid import and export is taken over (10), the overcoat (15) of (11), water coolant flow deflector (16) to multistage guide shell (7), interior cover (17) is formed by having; Wherein, the water coolant flow deflector be spirrillum be wrapped in that interior cover (17) is gone up and with interior cover (17) concrete mutually, overcoat (15) gap is enclosed within outside the flow deflector, interior cover and the overcoat two ends are fixed shuts.
3, gas-lift fermentation reactor according to claim 1 and 2 is characterized in that: sieve plate (5) by orifice plate (20), intersection is given distribution gusset (18), manhole plate (19) is formed; Wherein, intersection is given distribution gusset (18) and orifice plate (20) concrete mutually; Orifice plate (20) has a manhole ringwise on the anchor ring; Manhole plate (19) covers on manhole and with orifice plate (20) fixedlys connected; All have many identical gas-liquid distribution holes on manhole plate (19) and the orifice plate (20).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91226248 CN2099763U (en) | 1991-10-12 | 1991-10-12 | Air-lift type fermentation reactor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91226248 CN2099763U (en) | 1991-10-12 | 1991-10-12 | Air-lift type fermentation reactor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2099763U true CN2099763U (en) | 1992-03-25 |
Family
ID=4932368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 91226248 Granted CN2099763U (en) | 1991-10-12 | 1991-10-12 | Air-lift type fermentation reactor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2099763U (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1078247C (en) * | 1998-01-22 | 2002-01-23 | 中国科学院生态环境研究中心 | Bioreactor with baffling element |
| WO2006122498A1 (en) | 2005-05-20 | 2006-11-23 | Tsinghua University | Airlift circumfluent reactor needing no foreign air source |
| CN105779273A (en) * | 2016-04-26 | 2016-07-20 | 淮南师范学院 | Horizontal internal and external double-circulation airlift bioreactor |
| CN114107033A (en) * | 2021-11-19 | 2022-03-01 | 安徽宝杰生物科技有限公司 | Biological feed fermentation system with oxygen content adjusting function |
| US11566215B2 (en) | 2016-08-27 | 2023-01-31 | 3D Biotek Llc | Bioreactor with scaffolds |
-
1991
- 1991-10-12 CN CN 91226248 patent/CN2099763U/en active Granted
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1078247C (en) * | 1998-01-22 | 2002-01-23 | 中国科学院生态环境研究中心 | Bioreactor with baffling element |
| WO2006122498A1 (en) | 2005-05-20 | 2006-11-23 | Tsinghua University | Airlift circumfluent reactor needing no foreign air source |
| AU2006246862B2 (en) * | 2005-05-20 | 2011-04-21 | Tsinghua University | Airlift circumfluent reactor needing no foreign air source |
| CN105779273A (en) * | 2016-04-26 | 2016-07-20 | 淮南师范学院 | Horizontal internal and external double-circulation airlift bioreactor |
| US11566215B2 (en) | 2016-08-27 | 2023-01-31 | 3D Biotek Llc | Bioreactor with scaffolds |
| US11926810B2 (en) | 2016-08-27 | 2024-03-12 | 3D Biotek, Llc | Bioreactor with scaffolds |
| CN114107033A (en) * | 2021-11-19 | 2022-03-01 | 安徽宝杰生物科技有限公司 | Biological feed fermentation system with oxygen content adjusting function |
| CN114107033B (en) * | 2021-11-19 | 2022-10-28 | 安徽宝杰生物科技有限公司 | Biological feed fermentation system with oxygen content adjusting function |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C15 | Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993) | ||
| RN01 | Renewal of patent term | ||
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |