CN209843656U

CN209843656U - Long-shaft multi-level rod ion focusing transmission component

Info

Publication number: CN209843656U
Application number: CN201920479314.2U
Authority: CN
Inventors: 刘召贵; 周专; 张相明; 姜永泽; 周立
Original assignee: Jiangsu Skyray Instrument Co Ltd
Current assignee: Jiangsu Skyray Instrument Co Ltd
Priority date: 2019-04-10
Filing date: 2019-04-10
Publication date: 2019-12-24
Anticipated expiration: 2029-04-10

Abstract

The utility model discloses a long-axis multistage rod ion focusing transmission component, which comprises a plurality of long-axis equal-diameter conducting electrode rods which form a space symmetrical structure around the same axis and form a conical structure with an entrance aperture larger than an exit aperture; the supporting seats are provided with internal through holes, the long-axis equal-diameter conductive electrode rods are fixedly connected to the inner sides of the through holes, the caliber of an outlet is more than or equal to 2mm, and the diameter of each long-axis equal-diameter conductive electrode rod is more than or equal to 1mm and less than or equal to 50 mm; the support seat is connected with the long-axis equal-diameter conducting electrode rod in a staggered manner, and is connected with an external power supply which can form a radio-frequency electric field and an axial gradient electric field in a conical structure together with the long-axis conducting electrode rod; the utility model greatly reduces the volume of the prior device and reduces the cost; the ion detection device can also obviously improve the purification effect of the ion beam, reduce the pollution of the ion source to the mass spectrometer, reduce the detection background and greatly improve the detection sensitivity.

Description

Long-shaft multi-level rod ion focusing transmission component

Technical Field

The utility model belongs to the technical field of the ion focusing transmission and specifically relates to a based on multistage pole ion focusing transmission part of major axis.

Background

The mass spectrometer is a high-sensitivity and high-resolution instrument for detecting chemical components of substances, and is characterized by that firstly, the sample is converted into gaseous ions, then the ions are separated according to the mass-to-charge ratio (m/z) by means of electric field, then the intensity of the ions is measured to form a mass spectrogram, and according to the mass spectrogram the chemical components of the substances can be qualitatively or quantitatively obtained.

Analyte ions for analysis by mass spectrometry can be generated by any of a variety of ionization systems. For example, AP-MALDI, APPI, ESI, APCI, and ICP systems can be used in mass spectrometry systems to generate ions. Many of these systems generate ions at or near atmospheric pressure (760 Torr). After the ions are generated, the analyte ions must be introduced or sampled into the mass spectrum. Typically, the analyzer portion of the mass spectrometer is held at 10^-4Torr to 10^-8High vacuum level of Torr. In practice, sampling the ions involves transporting the analyte ions in the form of a finely defined ion beam from the ion source via one or more intermediate vacuum chambers to a high vacuum mass spectrometer chamber. Each of the intermediate vacuum chambers maintains a vacuum level between the front and rear chambers, wherein the analyte ions transition in a stepwise manner from a pressure level associated with ion formation to a pressure level of the mass spectrometer. In most applications, it is desirable to transport ions through various chambers of a mass spectrometer system without significant ion loss, typically using ion guidance in an MS system to move ions in a defined direction.

The ion transmission product on the market is a six-grade rod with uniform diameter, and the diameter of an inlet and the diameter of an outlet formed by 6 inscribed circles of the six-grade rod are the same. After a radio frequency electric field and an axial gradient electric field are applied to the six-stage rod, ions can be focused inside the six-stage rod and then enter an outlet from an inlet, and as the ion source is in the atmospheric pressure outside the vacuum, the ions and the neutral gas are driven by the pressure difference between the vacuum and the atmospheric pressure and enter through a small narrow hole, the aperture of the inlet is enlarged, the total amount of the ions and the neutral gas which can enter the vacuum can be increased, but a vacuum pump with higher pumping speed is needed to maintain the separation of the ions and the neutral gas, so that the necessary background vacuum for better detecting the ions is ensured. And correspondingly, the inscribed circle of the six-stage rod needs to be larger, so that most of the ions enter the six-stage rod after rapidly expanding through the small hole, are restrained by the alternating current electric field and then are focused. However, after the diameter of the inscribed circle of the six-stage rod is large, the focusing effect at the outlet is poor, and more ions are diffused and lost after exiting the six-stage rod and are difficult to enter the lower-stage ion optical path, so that a method and a method are needed to be found, wherein the method and the method can obtain more ions to be detected at the inlet, better focused ions at the outlet and better detection background to obtain higher sensitivity.

SUMMERY OF THE UTILITY MODEL

In view of the above, at least one of the above-mentioned defects in the prior art needs to be overcome, and the present invention provides a long-axis multistage rod ion focusing transmission component, which includes a plurality of long-axis equal-diameter conducting electrode rods, wherein the long-axis equal-diameter conducting electrode rods form a spatially symmetrical structure around the same axis, and form a conical structure with an entrance aperture larger than an exit aperture; the supporting seats are provided with internal through holes, the long-axis equal-diameter conducting electrode rods are fixedly connected to the inner sides of the through holes, the caliber of the outlet is more than or equal to 2mm, and the diameter of each long-axis equal-diameter conducting electrode rod is more than or equal to 1mm and less than or equal to 50 mm;

the support seat is connected with the long-axis equal-diameter conducting electrode rod in a staggered mode, and an external power supply which can form a radio-frequency electric field and an axial gradient electric field in the conical structure together with the long-axis equal-diameter conducting electrode rod is connected.

According to the prior art in the background of the patent, the apertures of an ion beam inlet and an ion beam outlet are the same, so that the problem that the cost and the complexity of the whole equipment cannot be increased and the focusing capacity can be improved by a low cost or a simple method cannot be simultaneously solved; the long-shaft multistage-rod ion focusing transmission component disclosed by the utility model adopts the long-shaft multistage-rod ion focusing transmission component with the ion beam inlet aperture larger than the ion beam outlet aperture, so that the volume of the existing device can be greatly reduced on the basis of adopting the long-shaft rod piece unchanged in the prior art and having low cost, and meanwhile, the cost can be reduced on equipment for providing an electric field and vacuum; the ion beam purification effect can be obviously improved, the ion beam can be further focused through the further change of the electric field along the axis, most neutral molecules in the ion beam can be eliminated, the ionization efficiency is improved, the pollution of an ion source to a mass spectrometer is reduced, the detection background is reduced, the detection sensitivity can be greatly improved, and by adopting the structure, the ion detection equipment with low cost, simple structure and higher sensitivity can be formed.

The ion source is positioned in the atmospheric pressure outside the vacuum, ions and neutral gas are driven by the pressure difference between the vacuum and the atmospheric pressure together, and enter the multi-stage rod ion focusing transmission device through a small narrow hole, and after a radio frequency electric field and an axial gradient electric field are applied to the multi-stage rod body, the ions can be focused inside the multi-stage rod and enter the outlet from the inlet; the multistage pole entry bore is big, can make more ions, after the aperture expands rapidly, get into in the multistage pole, receive alternating current electric field's restraint, then focus, multistage pole export inscribed circle diameter is less than entry inscribed circle diameter simultaneously, because the even electric field that inside electric field and original structure formed is different, more be favorable to exit ion focusing, make more ions go out behind six grades of poles, better entering subordinate's ion light path, simultaneously because the toper structure that forms, make ion and neutral particle's proportion further expand, can bring better detection background from this, promote the sensitivity that detects.

In addition, according to the utility model discloses a multistage pole ion focusing transmission part of major axis still has following additional technical characteristics:

further, the long-axis equal-diameter conducting electrode rod is a long-axis circular metal rod or a long-axis circular rod with a conducting coating on the outer part or a long-axis circular rod with a conducting component in the inner part.

Further, the number of the conducting electrode rods is 4 or 6 or 8.

Further, the taper of the space symmetry structure is less than or equal to 30 degrees and greater than 0 degree. When the taper of the space symmetric structure is 0, the structure is the same as the traditional structure, and a better structure with an outlet caliber smaller than an inlet caliber cannot be formed;

further, the aperture of the inlet is less than or equal to 75 mm.

Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.

Drawings

The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:

fig. 1 is a schematic structural diagram of an embodiment of the present invention;

fig. 2 is a schematic view of a multi-stage rod member according to an embodiment of the present invention.

The structure comprises a conical structure 1, a long-axis equal-diameter conducting electrode rod 2, a supporting seat 3, an inlet 11, an outlet 12, an insulating plate 31, a first conducting strip 32 and a second conducting strip 33.

Detailed Description

Reference will now be made in detail to the embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar functions throughout; the embodiments described below by referring to the drawings are exemplary only for explaining the present invention, and should not be construed as limiting the present invention.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "bottom", "top", "front", "rear", "inner", "outer", "lateral", "vertical", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are used merely for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "coupled," "communicating," "connected," and "coupled" are to be construed broadly and may, for example, be fixedly connected, integrally connected, or detachably connected; may be communication within two elements; can be directly connected or indirectly connected through an intermediate medium; the term "fit" can be a surface-to-surface fit, a point-to-surface or a line-to-surface fit, and also includes a hole-axis fit, and a person skilled in the art can understand the specific meaning of the above terms in the present invention in specific situations.

The utility model has the following conception, the utility model provides a long-axis multistage rod ion focusing transmission component, which is simple and convenient in mechanism manufacture and low in cost by adopting the long-axis multistage rod ion focusing transmission component with the diameter of an ion beam inlet larger than that of an ion beam outlet, and the progressive multipole rod adjusts the ion beam, so that the ion beam is focused in an electric field between the multipole rods with a large inlet and a small outlet, thereby facilitating the transmission of the ion beam; the utility model discloses still improve the purification effect to the ion beam, clear away the neutral molecule of the overwhelming majority in the ion beam, improved ionization efficiency, reduced the pollution of ion source to mass spectrometer.

As shown, according to an embodiment of the present invention, the long-axis multi-stage rod ion focusing transmission component includes: the electrode comprises a plurality of long-axis equal-diameter electrode guide rods 2, wherein the long-axis equal-diameter electrode guide rods 2 form a space symmetrical structure, namely a conical structure 1, around the same axis to form the conical structure 1 with the aperture of an inlet 11 larger than that of an outlet 12; the support seats 3 are provided with internal through holes, the long-axis equal-diameter electrode guide rods 2 are fixedly connected to the inner sides of the through holes, the caliber of the outlet 12 is greater than or equal to 2mm, and the diameter of each long-axis equal-diameter electrode guide rod 2 is greater than or equal to 1mm and smaller than or equal to 50 mm;

the support seat 3 is connected with the long-axis equal-diameter conducting electrode rod 2 in a staggered mode, and is connected with an external power supply which can form a radio-frequency electric field and an axial gradient electric field in the conical structure 1 together with the long-axis equal-diameter conducting electrode rod 2.

In addition, according to the utility model discloses a long axis multistage pole ion focusing transmission part still has following additional technical characteristics:

according to some embodiments of the present invention, the long-axis equal-diameter conductive electrode rod 2 is a long-axis circular metal rod or a long-axis circular rod having a conductive coating on the outside or a long-axis circular rod having a conductive part inside.

According to some embodiments of the present invention, the long-axis equal-diameter conducting electrode rods 2 are 4, 6 or 8.

According to some embodiments of the present invention, the taper of the space symmetric structure is less than or equal to 30 degrees and greater than 0 degree.

According to some embodiments of the invention, the 11 bores of the inlets are less than or equal to 75 mm.

Any reference to "one embodiment," "an embodiment," "example embodiment," etc., means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the invention; the schematic representations in various places in the specification do not necessarily refer to the same embodiment; further, when a particular feature, structure, or characteristic is described in connection with any embodiment, it is submitted that it is within the purview of one skilled in the art to effect such feature, structure, or characteristic in connection with other ones of the embodiments.

While the invention has been described in detail with reference to a number of illustrative embodiments thereof, it should be understood that numerous other modifications and embodiments can be devised by those skilled in the art that will fall within the spirit and scope of the principles of this invention; in particular, reasonable variations and modifications are possible in the component parts and/or arrangements of the subject combination arrangement within the scope of the foregoing disclosure, the drawings and the appended claims without departing from the spirit of the invention; except variations and modifications in the component parts and/or arrangements, the scope of which is defined by the appended claims and equivalents thereof.

Claims

1. The long-axis multistage-rod ion focusing transmission component is characterized by comprising a plurality of long-axis equal-diameter conducting electrode rods, wherein the long-axis equal-diameter conducting electrode rods form a space symmetrical structure around the same axis to form a conical structure with an inlet caliber larger than an outlet caliber; the supporting seats are provided with internal through holes, the long-axis equal-diameter conducting electrode rods are fixedly connected to the inner sides of the through holes, the caliber of the outlet is more than or equal to 2mm, and the diameter of each long-axis equal-diameter conducting electrode rod is more than or equal to 1mm and less than or equal to 50 mm;

2. The long-axis multi-stage rod ion focusing transmission member as claimed in claim 1, wherein the long-axis equal-diameter conducting electrode rods are long-axis circular metal rods or long-axis circular rods with conducting coatings on the outside or long-axis circular rods with conducting parts inside.

3. The long-axis multi-stage rod ion focusing transmission member of claim 1, wherein said conductive electrode rods are 4, 6 or 8.

4. The long-axis multi-stage rod ion focusing transmission member of claim 1, wherein the taper of the spatially symmetric structure is equal to or less than 30 degrees and greater than 0 degree.

5. The long-axis multi-stage rod ion focusing transmission member of claim 1, wherein the entrance aperture is 75mm or less.