CN209778275U - Continuous replenishing device for aerosol propellant - Google Patents
Continuous replenishing device for aerosol propellant Download PDFInfo
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- CN209778275U CN209778275U CN201920595698.4U CN201920595698U CN209778275U CN 209778275 U CN209778275 U CN 209778275U CN 201920595698 U CN201920595698 U CN 201920595698U CN 209778275 U CN209778275 U CN 209778275U
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Abstract
the utility model discloses a device is added in succession to aerosol propellant, including first and second withstand voltage container, feed liquor pipe is connected to the withstand voltage container one side, and the opposite side passes through the pipeline to be connected with second withstand voltage container, is equipped with the relief pressure valve on the pipeline, intake pipe is connected to two opposite sides of withstand voltage container, and the intake pipe end is used for connecting the preparation jar, is equipped with the automatic valve in the intake pipe, still be connected with flow control valve in the intake pipe, flow control valve sets up in the one side that second withstand voltage container was kept away from to the automatic valve, first withstand voltage container is used for storing the coexistent propellant of gas-liquid, and second withstand voltage container is used for storing the gaseous propellant, and the propellant is carried to the preparation jar from first withstand voltage container, pipeline, second. The device can continuously supplement the propellant for the preparation tank, the liquid medicine does not need to be filled in the process of supplementing the propellant, and the production efficiency of the aerosol is improved.
Description
Technical Field
the utility model relates to an aerosol processing field, concretely relates to device is added in succession to aerosol propellant.
Background
In the production of medicinal aerosol, tetrafluoroethane, heptafluoropropane, and the like are commonly used as a power source and an energy source for drug ejection, that is: the propellant is also part of the preparation medicine. The filling of the medicinal aerosol can adopt a low-temperature filling mode or a normal-temperature high-pressure filling mode, and the low-temperature filling mode has the defects of high energy consumption, moisture condensation and the like, so that the normal-temperature high-pressure filling mode is generally used at present. Before high-pressure filling, the aerosol is prepared by adding the prescribed amount of medicine, propellant and other auxiliary materials into a high-pressure resistant closed preparation tank.
In a closed formulation tank, the propellant is in two states: 1. a liquid state with the drug; 2. the gas above the liquid. Along with the occurrence of the filling process, the liquid state in the closed preparation tank is reduced, the liquid level is reduced, the gaseous space is correspondingly increased, the liquid propellant is gasified into the gaseous space, the concentration of the medicine in the preparation tank is gradually increased, correspondingly, the concentration of the medicine in each bottle of the filled liquid medicine is also gradually increased, and if the concentration of the medicine is continuously increased, the medicine is finally unqualified.
The existing coping method is to fill a certain amount of medicine bottles and then stop filling, then add a proper amount of propellant into a preparation tank, stir uniformly and then fill. Depending on the size of the batch and the preparation tank, a batch of aerosol medicines are usually produced, the machine is stopped for 2 to 5 times in the midway, and the propellant is manually added. This method has at least 2 disadvantages: firstly, time is consumed, and about 20 minutes is consumed when the single supplement is completed until the re-filling can be carried out; secondly, the sampling quantity and the detection quantity of the process are increased.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problem, the utility model discloses a device is added in succession to aerosol propellant, the device can be in succession for the preparation jar adds the propellant, and the process of adding the propellant need not to stop the filling liquid medicine, improves the production efficiency of aerosol.
The utility model discloses a following technical scheme realizes:
The utility model provides a device is supplemented in succession to aerosol propellant, includes first and second pressure vessel of pressure vessel, and the feed liquor pipe is connected to pressure vessel one side, and the opposite side passes through the pipeline to be connected with second pressure vessel, is equipped with the relief pressure valve on the pipeline, intake pipe is connected to second opposite side of pressure vessel, and the intake pipe end is used for connecting the preparation jar, is equipped with the automatic valve in the intake pipe, still be connected with flow control valve in the intake pipe, flow control valve sets up in the one side that second pressure vessel was kept away from to the automatic valve, first pressure vessel is used for storing the coexistent propellant of gas-liquid, and second pressure vessel is used for storing gaseous propellant, and the propellant is carried to the preparation jar from first pressure vessel, pipeline, second pressure.
in the utility model, the propellant enters into the first pressure-resistant container from the liquid inlet pipe, the propellant in the first pressure-resistant container is in a gas-liquid coexisting state, the saturated vapor in the first pressure-resistant container flows to the second pressure-resistant container along the pipeline, the pressure reducing valve on the pipeline can control the gas pressure of the gas flowing into the second pressure-resistant container, when the pressure of the gaseous propellant flowing into the second pressure-resistant container reaches the preset value of the pressure reducing valve (the preset value is lower than the gas pressure value of the saturated vapor in the first pressure-resistant container), the gas flow between the two pressure-resistant containers is stopped, when the liquid medicine in the preparation tank is continuously filled for a certain amount and the liquid medicine volume is reduced, the automatic valve and the flow regulating valve are opened, so that the gaseous propellant in the second pressure-resistant container flows into the preparation tank from the air inlet pipe, the propellant entering into the preparation tank just counteracts the' space effect, therefore, the change of the concentration of the medicine is avoided, the propellant can be continuously supplemented to the preparation tank by the supplementing device, the liquid medicine does not need to be filled in the process of supplementing the propellant, and the filling efficiency of the aerosol is improved.
The pressure reducing valve can adjust the air pressure in the pressure-resistant container II, the vapor in the pressure-resistant container II can automatically flow to the pressure-resistant container II without being driven by external force because the air pressure in the pressure-resistant container II is smaller than the saturated vapor pressure of the propellant at the set temperature, the vapor stops flowing until the air pressure in the pressure-resistant container II reaches the preset value of the pressure reducing valve, the flow regulating valve is used for regulating the flow of the propellant entering the preparation tank from the pressure-resistant container II, so that the propellant can be accurately regulated and controlled, the heating elements wrapped on the surfaces of the pressure-resistant container I, the pipeline, the pressure-resistant container II and the air inlet pipe are used for heating the whole replenishing device and the propellant, so that a temperature difference is generated between the replenishing device and the preparation tank, the air pressure is increased after the propellant is heated, the propellant automatically flows from the pressure-resistant container to the preparation.
Furthermore, the pressure container is connected with a first pressure sensor and a first valve, and the first valve is a manual valve.
Furthermore, the second pressure-resistant container is connected with a second pressure sensor and a second valve, and the second valve is a manual valve.
The utility model discloses in, pressure sensor one and pressure sensor two are used for monitoring the atmospheric pressure in withstand voltage container one, withstand voltage container two, when not enough pressure supply in withstand voltage container one the propellant can, valve one, valve two are used for when production finishes, and manual pressure release for withstand voltage container one, withstand voltage container two resumes withstand voltage container to the ordinary pressure state.
Furthermore, a third valve is connected to the liquid inlet pipe, and the third valve is a manual valve.
Furthermore, the pressure reducing valve is a precise pressure reducing valve, the flow regulating valve is a micro-flow regulating valve, and the first pressure sensor and the second pressure sensor are both precise pressure sensors.
Furthermore, a flow sensor is arranged on an air inlet pipe between the flow regulating valve and the preparation tank, and the flow sensor is a precise flow sensor.
The utility model discloses in, flow sensor is used for monitoring the flow that flows into the gaseous propellant in the preparation jar, improves the accuracy that the propellant was added, is favorable to preparing jar interior medicine concentration's regulation and balance, reduces medicine concentration's fluctuation.
Furthermore, a check valve is arranged on an air inlet pipe between the flow sensor and the preparation tank. Preventing the propellant vapour from flowing backwards.
Furthermore, the automatic valve and the heating element are controlled to be opened and closed through a control center, and the flow regulating valve, the flow sensor, the first pressure sensor and the second pressure sensor are all connected with the control center.
The utility model discloses in, the control center that can add, after the liquid medicine in the preparation jar reduces a quantitative, control center control heating element heating to open automatic valve, flow control valve to the propellant vapour of preparation jar quantitative addition according to preparation jar demand, the interior medicine concentration of preparation jar is adjusted to the accuracy. The control center can adopt the existing control equipment such as the existing PLC controller, and the structure, the working principle and the control logic of the control center are all existing, and the detailed description is omitted.
Further, the pressure resistance of the first pressure container and the second pressure container is more than 7 bar.
Preferably, the temperature difference between the temperature in the continuous replenishing device and the temperature in the preparation tank is 2-6 ℃.
Preferably, the first pressure-resistant container and the second pressure-resistant container are pressure-resistant bottles or pressure-resistant tanks.
The automatic valve is an electromagnetic valve or a pneumatic valve.
Compared with the prior art, the utility model, following advantage and beneficial effect have:
1. The utility model relates to a device is added in succession to aerosol propellant, the propellant enters into pressure vessel one from the feed liquor pipe, the propellant in pressure vessel one is the coexistence state of gas-liquid, saturated vapour in pressure vessel one flows to pressure vessel two along the pipeline, the atmospheric pressure of the gas that flows into in pressure vessel two can be controlled to the relief pressure valve on the pipeline, after gaseous propellant pressure that flows into pressure vessel two reaches the relief pressure valve default (this default is less than the saturated vapour atmospheric pressure value in pressure vessel one), stop gaseous flow between two pressure vessel, after the liquid medicine in the preparation jar is filled a certain amount and the liquid medicine volume reduces continuously, open automatic valve, flow control valve, make gaseous propellant in pressure vessel two flow into the preparation jar from the intake pipe, the propellant that gets into the preparation jar just offsets "space effect" that the liquid medicine liquid level reduces, the gaseous propellant that gets into just inhibits liquid propellant gasification, therefore, the change of the concentration of the medicine is avoided, the propellant can be continuously supplemented to the preparation tank by the supplementing device, the liquid medicine does not need to be stopped in the process of supplementing the propellant, and the filling efficiency of the aerosol is improved;
2. The utility model relates to a device is added in succession to aerosol propellant, atmospheric pressure in the withstand voltage container two can be adjusted to the relief pressure valve, because atmospheric pressure in withstand voltage container two is less than propellant saturation vapor pressure under the settlement temperature, consequently vapour in withstand voltage container one can automatic flow to withstand voltage container two, need not external drive, stops flowing after atmospheric pressure in withstand voltage container two reaches the relief pressure valve default, and flow control valve is used for adjusting withstand voltage container two and gets into the flow of the propellant in the preparation jar, the accurate regulation and control of being convenient for, the heating element of withstand voltage container one, pipeline, withstand voltage container two and intake pipe surface parcel is used for adding device and propellant for whole and intensification, makes and adds the device and produces the temperature difference between the preparation jar, and atmospheric pressure increases after the propellant intensifies, and the propellant is automatic from withstand voltage container two to the preparation jar under atmospheric pressure, supplements the propellant in the preparation jar, the automation degree is high.
Drawings
The accompanying drawings, which are included to provide a further understanding of the embodiments of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the principles of the invention. In the drawings:
Fig. 1 is a schematic structural diagram of the present invention.
Reference numbers and corresponding part names in the drawings:
1-a pressure-resistant container I, 11-a pressure sensor I, 12-a valve I, 2-a pressure-resistant container II, 21-a pressure sensor II, 22-a valve II, 3-a liquid inlet pipe, 31-a valve III, 4-a pressure reducing valve, 5-an air inlet pipe, 6-a check valve, 7-an automatic valve, 8-a flow regulating valve and 9-a flow sensor.
Detailed Description
To make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the following examples and drawings, and the exemplary embodiments and descriptions thereof of the present invention are only used for explaining the present invention, and are not intended as limitations of the present invention.
Example 1
As shown in figure 1, the utility model relates to a device for continuously adding aerosol propellant, which comprises a first pressure container 1 and a second pressure container 2, wherein one side of the first pressure container 1 is connected with a liquid inlet pipe 3, the other side is connected with the second pressure container 2 through a pipeline, a pressure reducing valve 4 is arranged on the pipeline, the other side of the second pressure container 2 is connected with an air inlet pipe 5, the tail end of the air inlet pipe 5 is used for connecting a preparation tank, an automatic valve 7 is arranged on the air inlet pipe 5, a flow regulating valve 8 is also connected on the air inlet pipe 5, the flow regulating valve 8 is arranged on one side of the automatic valve 7 far away from the pressure vessel 2, the pressure-resistant container I1 is used for storing propellant coexisting with gas and liquid, the pressure-resistant container II 2 is used for storing gaseous propellant, the propellant is conveyed from the pressure-resistant container I1 to the preparation tank, heating elements are wrapped on the surfaces of the pressure container I1, the pipeline, the pressure container II 2 and the air inlet pipe 5.
Further, the first pressure container 1 is connected with a first pressure sensor 11 and a first valve 12, and the first valve 12 is a manual valve.
Furthermore, the second pressure-resistant container 2 is connected with a second pressure sensor 21 and a second valve 22, and the second valve 22 is a manual valve.
Furthermore, a third valve 31 is connected to the liquid inlet pipe 3, and the third valve 31 is a manual valve.
Further, a flow sensor 9 is arranged on the air inlet pipe 5 between the flow regulating valve 8 and the preparation tank, and the flow sensor 9 is a precision flow sensor.
Example 2
As shown in figure 1, the utility model relates to a device for continuously adding aerosol propellant, which comprises a first pressure container 1 and a second pressure container 2, wherein one side of the first pressure container 1 is connected with a liquid inlet pipe 3, the other side is connected with the second pressure container 2 through a pipeline, a pressure reducing valve 4 is arranged on the pipeline, the other side of the second pressure container 2 is connected with an air inlet pipe 5, the tail end of the air inlet pipe 5 is used for connecting a preparation tank, an automatic valve 7 is arranged on the air inlet pipe 5, a flow regulating valve 8 is also connected on the air inlet pipe 5, the flow regulating valve 8 is arranged on one side of the automatic valve 7 far away from the pressure vessel 2, the pressure-resistant container I1 is used for storing propellant coexisting with gas and liquid, the pressure-resistant container II 2 is used for storing gaseous propellant, the propellant is conveyed from the pressure-resistant container I1 to the preparation tank, heating elements are wrapped on the surfaces of the pressure container I1, the pipeline, the pressure container II 2 and the air inlet pipe 5.
Further, the first pressure container 1 is connected with a first pressure sensor 11 and a first valve 12, and the first valve 12 is a manual valve.
Furthermore, the second pressure-resistant container 2 is connected with a second pressure sensor 21 and a second valve 22, and the second valve 22 is a manual valve.
Furthermore, a third valve 31 is connected to the liquid inlet pipe 3, and the third valve 31 is a manual valve.
Further, the pressure reducing valve 4 is a precise pressure reducing valve, the flow regulating valve 8 is a micro-flow regulating valve, and the first pressure sensor 11 and the second pressure sensor 21 are precise pressure sensors.
Further, a flow sensor 9 is arranged on the air inlet pipe 5 between the flow regulating valve 8 and the preparation tank, and the flow sensor 9 is a precision flow sensor.
Furthermore, a check valve 6 is arranged on the air inlet pipe 5 between the flow sensor 9 and the preparation tank.
Furthermore, the automatic valve 7 and the heating element are controlled to be opened and closed by a control center, and the flow regulating valve 8, the flow sensor 9, the first pressure sensor 11 and the second pressure sensor 21 are all connected with the control center.
Further, the pressure resistance of the first pressure container 1 and the second pressure container 2 is more than 7 bar.
the above-mentioned embodiments, further detailed description of the objects, technical solutions and advantages of the present invention, it should be understood that the above description is only the embodiments of the present invention, and is not intended to limit the scope of the present invention, and any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (10)
1. The device is characterized by comprising a first pressure-resistant container (1) and a second pressure-resistant container (2), wherein one side of the first pressure-resistant container (1) is connected with a liquid inlet pipe (3), the other side of the first pressure-resistant container is connected with the second pressure-resistant container (2) through a pipeline, a pressure reducing valve (4) is arranged on the pipeline, the other side of the second pressure-resistant container (2) is connected with an air inlet pipe (5), the tail end of the air inlet pipe (5) is used for connecting a preparation tank, an automatic valve (7) is arranged on the air inlet pipe (5), a flow regulating valve (8) is further connected onto the air inlet pipe (5), the flow regulating valve (8) is arranged on one side, away from the second pressure-resistant container (2), of the automatic valve (7), the first pressure-resistant container (1) is used for storing a propellant with gas and liquid, the second pressure-resistant container, heating elements are wrapped on the surfaces of the pressure container I (1), the pipeline, the pressure container II (2) and the air inlet pipe (5).
2. A device for the continuous replenishment of aerosol propellant as claimed in claim 1 wherein a first pressure-resistant container (1) is connected to a first pressure sensor (11) and a first valve (12), the first valve (12) being a manual valve.
3. a device for continuously adding propellant aerosol as claimed in claim 2 wherein a second pressure-resistant container (2) is connected to a second pressure sensor (21) and a second valve (22), the second valve (22) being a manual valve.
4. A device for the continuous replenishment of aerosol propellant as claimed in claim 1 wherein a third valve (31) is connected to the inlet conduit (3), the third valve (31) being a manual valve.
5. A device for continuously replenishing aerosol propellant as claimed in claim 3, wherein said pressure reducing valve (4) is a precision pressure reducing valve, said flow regulating valve (8) is a micro-flow regulating valve, and said first pressure sensor (11) and said second pressure sensor (21) are precision pressure sensors.
6. A device for continuously replenishing aerosol propellant as claimed in claim 5, wherein the air inlet conduit (5) between the flow control valve (8) and the dispensing canister is provided with a flow sensor (9), and the flow sensor (9) is a precision flow sensor.
7. A device for the continuous replenishment of aerosol propellant as claimed in claim 6 wherein a check valve (6) is provided in the inlet conduit (5) between the flow sensor (9) and the dispensing canister.
8. A device for continuously adding aerosol propellant as claimed in claim 6, wherein the automatic valve (7) and the heating element are controlled by a control center, and the flow control valve (8), the flow sensor (9), the first pressure sensor (11) and the second pressure sensor (21) are connected with the control center.
9. A device for the continuous replenishment of aerosol propellant as claimed in claim 1 wherein the pressure resistance of the first (1) and second (2) pressure resistant containers is greater than 7 bar.
10. A device for the continuous replenishment of aerosol propellant as claimed in claim 1 wherein the first and second pressure resistant containers are pressure resistant bottles or canisters.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920595698.4U CN209778275U (en) | 2019-04-26 | 2019-04-26 | Continuous replenishing device for aerosol propellant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920595698.4U CN209778275U (en) | 2019-04-26 | 2019-04-26 | Continuous replenishing device for aerosol propellant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209778275U true CN209778275U (en) | 2019-12-13 |
Family
ID=68804375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920595698.4U Active CN209778275U (en) | 2019-04-26 | 2019-04-26 | Continuous replenishing device for aerosol propellant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209778275U (en) |
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2019
- 2019-04-26 CN CN201920595698.4U patent/CN209778275U/en active Active
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Liu Yanchun Inventor after: Li Yuanbo Inventor after: Gao Jian Inventor after: Zhang Jiali Inventor before: Wu Ming Inventor before: Liu Yanchun Inventor before: Li Yuanbo Inventor before: Gao Jian Inventor before: Zhang Jiali Inventor before: Shuai Xia |