CN209772148U - Centrifugal micro-fluidic test paper chip - Google Patents
Centrifugal micro-fluidic test paper chip Download PDFInfo
- Publication number
- CN209772148U CN209772148U CN201920325176.2U CN201920325176U CN209772148U CN 209772148 U CN209772148 U CN 209772148U CN 201920325176 U CN201920325176 U CN 201920325176U CN 209772148 U CN209772148 U CN 209772148U
- Authority
- CN
- China
- Prior art keywords
- channel
- pool
- liquid
- chip
- pad
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
a centrifugal microfluidic test strip chip comprising: the cover plate layer, the channel layer and the bottom plate layer; the cover plate layer is provided with a visual window, a liquid sample inlet to be tested, a cleaning liquid sample inlet, a vent hole and a cover plate chip fixing hole; the bottom plate layer is provided with a chromatographic test strip and a bottom plate chip fixing hole, wherein the chromatographic test strip consists of a sample pad, a nitrocellulose membrane, a combination pad and an absorption pad, the nitrocellulose membrane is positioned in the middle, and the sample pad and the absorption pad are respectively positioned at two ends; the combination pad is positioned between the sample pad and the nitrocellulose membrane, and a marker is arranged in the combination pad; the nitrocellulose membrane is provided with a detection line and a quality control line; the channel layer is provided with a detection area through hole, a cleaning solution pool, a cleaning solution channel, a liquid pool to be detected, a liquid channel to be detected, a sample injection pool, a ventilation channel and a channel chip fixing hole. The utility model provides a centrifugal micro-fluidic test paper chip that clean health, detection are accurate, degree of automation is high.
Description
Technical Field
The utility model relates to a micro-fluidic test paper chip detects technical field, and more specifically the utility model relates to a centrifugal micro-fluidic test paper chip that says so.
Background
Microfluidic chips are an emerging technology for manipulating and detecting chemical or biological samples on a chip. The microfluidic chip can integrate operation units of sample preparation, reaction, separation, detection and the like on a chip with a few square centimeters, and automatically complete the analysis process by controlling and controlling the fluid in the microchannel network. The micro-fluidic chip technology has the characteristics of small sample volume, high integration level and easy realization of automatic control and high-throughput analysis, so that the biochemical reaction operation on the micro-fluidic chip is more convenient and rapid than the conventional analysis sample pretreatment, and the cost is low.
The chromatographic test strip is widely applied to the fields of clinical diagnosis, food safety, environmental detection and the like. The detection method comprises chromaticity, fluorescence, magnetic detection and the like, depends on the labeled reactant in the combined pad, and if quantitative detection is carried out, such as fluorescence, a cleaning solution is required to be dripped after the reaction of the liquid to be detected is finished, the unbound labeled reactant in the detection area is removed, and the interference is reduced. In the conventional operation, an operator needs to add the liquid to be detected for reaction and wait for a period of time, then manually add the cleaning liquid, and then visually or simply detect the result by a detection device, so that the degree of automation is poor, and the detection efficiency is influenced.
therefore, how to provide a centrifugal microfluidic test paper chip which is clean and sanitary, accurate in detection and high in automation degree is a problem which needs to be solved urgently by the technical personnel in the field.
SUMMERY OF THE UTILITY MODEL
in view of the above, the utility model provides a centrifugal microfluidic test paper chip, combine microfluidic chip and chromatography test paper strip, liquid is most inside the chip after the reaction, and is more sanitary than the independent test paper strip; liquid enters the next stage through centrifugation, different liquids are guaranteed to enter at different times through different centrifugal rotating speeds, and after the liquid to be detected and the cleaning liquid are added, a user delivers the liquid to a centrifugal detection instrument to complete subsequent work without waiting for time and performing subsequent manual operation, so that the automation degree is improved.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
A centrifugal microfluidic test strip chip comprising: the cover plate layer and the bottom plate layer are respectively and correspondingly arranged at the top and the bottom of the channel layer and are in sealing fit with the channel layer;
The cover plate layer is provided with a visual window, a liquid sample inlet to be tested, a cleaning liquid sample inlet, a vent hole and a cover plate chip fixing hole;
the bottom plate layer is provided with a chromatographic test strip and a bottom plate chip fixing hole, wherein the chromatographic test strip consists of a sample pad, a nitrocellulose membrane, a combination pad and an absorption pad, the nitrocellulose membrane is positioned in the middle, and the sample pad and the absorption pad are respectively positioned at two ends; the combination pad is positioned between the sample pad and the nitrocellulose membrane, and markers are arranged in the combination pad and comprise enzyme markers, luminescent markers, colloidal gold markers, fluorescent markers, magnetic particle markers and the like; the nitrocellulose membrane is provided with a detection line and a quality control line;
The channel layer is provided with a detection area through hole, a cleaning liquid pool, a cleaning liquid channel, a liquid pool to be detected, a liquid channel to be detected, a sample injection pool, a ventilation channel and a channel chip fixing hole; the liquid pool to be detected is communicated with the liquid sample inlet hole to be detected; the cleaning liquid channel is communicated with the cleaning liquid pool and the sample injection pool, and the cleaning liquid pool is communicated with the cleaning liquid sample injection hole; the liquid channel to be detected is communicated with the liquid pool to be detected and the sample injection pool; the ventilation channel is communicated with the sample feeding pool and the ventilation hole; the detection area through hole is arranged corresponding to the visual window and the chromatography test strip; the sample injection pool is communicated with the bottom plate layer, and liquid in the sample injection pool is contacted with the chromatographic test strip;
the cleaning liquid pool, the cleaning liquid channel, the liquid pool to be tested, the liquid channel to be tested and the ventilation channel are all separated from the bottom plate layer.
preferably, in the centrifugal microfluidic test paper chip, the nitrocellulose membrane of the chromatography test paper strip is arranged corresponding to the detection area through hole and the visual window, and the reaction state of the detection line and the quality control line on the nitrocellulose membrane can be observed through the visual window and the detection area through hole; the sample pad of chromatography test paper strip with advance kind of pond and correspond the setting, make advance liquid in the kind pond and can flow to in the sample pad, progressively get into by the chromatography combine the pad the cellulose nitrate membrane absorption pad carries out a series of reactions.
Preferably, in the centrifugal microfluidic test paper chip, the visible window is an open through hole.
Preferably, in the centrifugal microfluidic test paper chip, the cross sections of the cover plate layer, the channel layer and the bottom plate layer are the same, and the cross section includes, but is not limited to, a rectangle, and may also be a sector.
preferably, in the centrifugal microfluidic test paper chip, the shape of the cleaning solution channel includes, but is not limited to, a wave shape, the wave shape can lengthen the length of the channel, and can also be an S shape or an arc shape.
Preferably, in the centrifugal microfluidic test strip chip described above, the shape of the vent channel includes, but is not limited to, a zigzag shape, and the zigzag channel can lengthen the length of the channel, and can also be S-shaped or arc-shaped.
Preferably, in the centrifugal microfluidic test paper chip, the cover plate chip fixing holes, the channel chip fixing holes and the bottom plate chip fixing holes have the same shape and are arranged in a superposed manner to form chip fixing holes penetrating through the centrifugal microfluidic test paper chip, the centrifugal microfluidic test paper chip is fixed on a centrifugal detector through the chip fixing holes in a centrifugal process, and the centrifugal microfluidic test paper chip rotates by taking the chip fixing holes as a circle center to carry out centrifugation.
preferably, in the above centrifugal microfluidic test paper chip, the cleaning solution pool and the solution pool to be tested are both located on one side of the sample injection pool close to the channel chip fixing hole, and in the centrifugal process, the cleaning solution pool and the solution in the solution pool to be tested can be driven by centrifugal force to respectively flow from the cleaning solution channel and the solution channel to be tested to the sample injection pool.
Preferably, in the centrifugal microfluidic test paper chip, in the channel layer, the detection area through hole, the cleaning solution pool, the cleaning solution channel, the liquid pool to be detected, the vent channel, the liquid channel to be detected, and the sample injection pool are sequentially arranged on one side of the channel chip fixing hole from near to far;
when the centrifugal test paper is centrifuged at a low rotating speed, the centrifugal microfluidic test paper chip is fixed on a rotating shaft of the centrifugal detector through the chip fixing hole, so that the centrifugal microfluidic test paper chip rotates by taking the chip fixing hole as a circle center for centrifugation, and the liquid flowing process is as follows:
(1) Adding the liquid to be detected into the liquid pool to be detected, centrifuging at a low rotating speed, and allowing the liquid to be detected to enter the sample injection pool from the liquid pool to be detected;
(2) Standing, enabling a liquid to be detected to contact the sample pad of the chromatographic test strip, enabling the liquid to enter the binding pad through chromatography, enabling the liquid to be detected to fully react with the marker in the binding pad to form a labeled reaction liquid, enabling the labeled reaction liquid to enter the nitrocellulose membrane, enabling the labeled reaction liquid to react with corresponding reagents in a detection line and a quality control line on the nitrocellulose membrane, and enabling the rest liquid to enter the absorption pad;
(3) Performing high-speed centrifugation, wherein cleaning liquid in the cleaning liquid pool enters the sample injection pool through the cleaning liquid channel;
(4) When the test strip is static, the cleaning solution contacts the sample pad of the chromatographic test strip, enters the binding pad, the nitrocellulose membrane and the absorption pad through chromatography, and residual unbound reagent on the nitrocellulose membrane is cleaned, so that the interference in result reading is avoided.
Preferably, in the centrifugal microfluidic test paper chip, the driving force of the liquid in the centrifugal microfluidic test paper chip is a centrifugal force.
According to the technical scheme, compared with the prior art, the utility model discloses a centrifugal microfluidic test paper chip, which combines the microfluidic chip with a chromatography test paper strip, most of the liquid after reaction is in the chip, and the chip is more sanitary than a single test paper strip; liquid enters the next stage through centrifugation, different liquids are guaranteed to enter at different times through different centrifugal rotating speeds, and after the liquid to be detected and the cleaning liquid are added, a user delivers the liquid to a centrifugal detection instrument to complete subsequent work without waiting for time and performing subsequent manual operation, so that the automation degree is improved.
drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a three-dimensional exploded view of the present invention;
FIG. 2 is a schematic diagram of a chromatographic test strip.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
The embodiment of the utility model discloses a centrifugal microfluidic test paper chip, which combines the microfluidic chip with a chromatography test paper strip, most of the liquid after reaction is in the chip, and the chip is more sanitary than a single test paper strip; liquid enters the next stage through centrifugation, different liquids are guaranteed to enter at different times through different centrifugal rotating speeds, and after the liquid to be detected and the cleaning liquid are added, a user delivers the liquid to a centrifugal detection instrument to complete subsequent work without waiting for time and performing subsequent manual operation, so that the automation degree is improved.
With reference to the accompanying drawings 1-2, the utility model discloses a centrifugal microfluidic test paper chip, include: the device comprises a cover plate layer 1, a channel layer 2 and a bottom plate layer 3, wherein the cover plate layer 1 and the bottom plate layer 3 are respectively and correspondingly arranged at the top and the bottom of the channel layer 2 and are in sealing fit with the channel layer 2;
The cover plate layer 1 is provided with a visual window 11, a liquid sample inlet 12 to be tested, a cleaning liquid sample inlet 13, a vent hole 14 and a cover plate chip fixing hole 15;
The bottom plate layer 3 is provided with a chromatographic test strip 31 and a bottom plate chip 32 fixing hole, wherein the chromatographic test strip 31 consists of a sample pad 33, a nitrocellulose membrane 34, a combination pad 36 and an absorption pad 35, the nitrocellulose membrane 34 is positioned in the middle, and the sample pad 33 and the absorption pad 35 are respectively positioned at two ends; the combination pad 36 is positioned between the sample pad 33 and the nitrocellulose membrane 34, and markers are arranged in the combination pad 36, and include enzyme markers, luminescent markers, colloidal gold markers, fluorescent markers, magnetic particle markers and the like; the nitrocellulose membrane 34 is provided with a detection line and a quality control line;
the channel layer 2 is provided with a detection area through hole 21, a cleaning solution pool 22, a cleaning solution channel 23, a liquid pool 24 to be detected, a liquid channel 25 to be detected, a sample injection pool 26, a ventilation channel 27 and a channel chip fixing hole 28; wherein, the liquid pool 24 to be tested is communicated with the liquid sample inlet 12; the cleaning solution channel 23 is communicated with the cleaning solution pool 22 and the sample injection pool 26, and the cleaning solution pool 22 is communicated with the cleaning solution sample injection hole 13; the liquid channel 25 to be tested is communicated with the liquid pool 24 to be tested and the sample inlet pool 26; the vent channel 27 is communicated with the sample feeding pool 26 and the vent hole 14; the detection area through hole 21 is arranged corresponding to the visual window 11 and the chromatographic test strip 31; the sample injection pool 26 is communicated with the bottom plate layer 3, and liquid in the sample injection pool 26 is contacted with the chromatographic test strip 31;
The cleaning liquid pool 22, the cleaning liquid channel 23, the liquid pool to be tested 24, the liquid channel to be tested 25 and the ventilation channel 27 are all separated from the bottom plate layer 3.
In order to further optimize the technical scheme, the nitrocellulose membrane 34 of the chromatography test strip 31 is arranged corresponding to the detection zone through hole 21 and the visual window 11, and the reaction state of the detection line and the quality control line on the nitrocellulose membrane 34 can be observed through the visual window 11 and the detection zone through hole 21; the sample pad 33 of the chromatographic test strip 31 is arranged corresponding to the sample cell 26, so that the liquid in the sample cell 26 can flow into the sample pad 33, and gradually enter the combination pad 36, the nitrocellulose membrane 34 and the absorption pad 35 through chromatography to perform a series of reactions.
In order to further optimize the above technical solution, the viewing window 11 is an open through hole.
in order to further optimize the technical scheme, the cross sections of the cover plate layer 1, the channel layer 2 and the bottom plate layer 3 are the same, and the shapes of the cross sections include, but are not limited to, rectangles, and fan-shaped.
In order to further optimize the above technical solution, the shape of the cleaning liquid channel 23 includes, but is not limited to, a wave shape, which can lengthen the length of the channel, and also can be an S shape or an arc shape.
In order to further optimize the above technical solution, the shape of the vent channel 27 includes, but is not limited to, a fold line shape, which can lengthen the length of the channel, and may also be an S-shape or an arc shape.
in order to further optimize the technical scheme, the cover plate chip fixing holes 15, the channel chip fixing holes 28 and the bottom plate chip fixing holes 32 are identical in shape and are arranged in a superposed mode to form chip fixing holes penetrating through the centrifugal microfluidic test paper chip, the centrifugal microfluidic test paper chip is fixed on a centrifugal detector through the chip fixing holes in the centrifugal process, and the centrifugal microfluidic test paper chip rotates by taking the chip fixing holes as circle centers to carry out centrifugation.
In order to further optimize the above technical solution, the cleaning solution pool 22 and the solution pool 24 to be measured are both located at one side of the sample injection pool 26 close to the channel chip fixing hole 28, and in the centrifugal process, the liquid in the cleaning solution pool 22 and the solution pool 24 to be measured can flow into the sample injection pool 26 from the cleaning solution channel 23 and the solution channel 25 to be measured respectively under the driving of centrifugal force.
in order to further optimize the technical scheme, in the channel layer 2, a detection area through hole 21, a cleaning solution pool 22, a cleaning solution channel 23, a liquid pool 24 to be detected, a ventilation channel 27, a liquid channel 25 to be detected and a sample injection pool 26 are sequentially arranged on one side of a channel chip fixing hole 28 from near to far;
When the centrifugal test paper is centrifuged at a low rotating speed, a centrifugal microfluidic test paper chip is fixed on a rotating shaft of a centrifugal detector through a chip fixing hole, so that the centrifugal microfluidic test paper chip rotates by taking the chip fixing hole as a circle center for centrifugation, and the liquid flowing process is as follows:
(1) Adding the liquid to be detected into the liquid pool 24 to be detected, centrifuging at low rotating speed, and allowing the liquid to be detected to enter the sample injection pool 26 from the liquid pool 24 to be detected through the liquid channel 25 to be detected;
(2) standing, allowing the liquid to be detected to contact with the sample pad 33 of the chromatographic test strip 31, entering the binding pad 36 under the action of chromatography, reacting with the marker in the binding pad 36 to generate a labeled reaction liquid, allowing the labeled reaction liquid to enter the nitrocellulose membrane 34, reacting with the corresponding reagents in the detection line and the quality control line on the nitrocellulose membrane 34, and allowing the rest of the liquid to enter the absorption pad 35;
(3) Centrifuging at a high speed, and enabling cleaning liquid in the cleaning liquid pool 22 to enter the sample injection pool 26 through the cleaning liquid channel 23;
(4) when the test strip is static, the cleaning solution contacts the sample pad 33 of the chromatographic test strip 31 and gradually enters the binding pad 36, the nitrocellulose membrane 34 and the absorption pad 35 through chromatography, so that residual unbound reagent on the nitrocellulose membrane 34 is cleaned, and the interference in result reading is avoided.
in order to further optimize the technical scheme, the driving force of the liquid in the centrifugal microfluidic test paper chip is centrifugal force.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. A centrifugal microfluidic test paper chip is characterized by comprising: the cover plate layer and the bottom plate layer are respectively and correspondingly arranged at the top and the bottom of the channel layer and are in sealing fit with the channel layer;
The cover plate layer is provided with a visual window, a liquid sample inlet to be tested, a cleaning liquid sample inlet, a vent hole and a cover plate chip fixing hole;
the bottom plate layer is provided with a chromatographic test strip and a bottom plate chip fixing hole, wherein the chromatographic test strip consists of a sample pad, a nitrocellulose membrane, a combination pad and an absorption pad, the nitrocellulose membrane is positioned in the middle, and the sample pad and the absorption pad are respectively positioned at two ends; the conjugate pad is positioned between the sample pad and the nitrocellulose membrane, and a label is disposed in the conjugate pad; the nitrocellulose membrane is provided with a detection line and a quality control line;
The channel layer is provided with a detection area through hole, a cleaning liquid pool, a cleaning liquid channel, a liquid pool to be detected, a liquid channel to be detected, a sample injection pool, a ventilation channel and a channel chip fixing hole; the liquid pool to be detected is communicated with the liquid sample inlet hole to be detected; the cleaning liquid channel is communicated with the cleaning liquid pool and the sample injection pool, and the cleaning liquid pool is communicated with the cleaning liquid sample injection hole; the liquid channel to be detected is communicated with the liquid pool to be detected and the sample injection pool; the ventilation channel is communicated with the sample feeding pool and the ventilation hole; the detection area through hole is arranged corresponding to the visual window and the chromatography test strip; the sample injection pool is communicated with the bottom plate layer, and liquid in the sample injection pool is contacted with the chromatographic test strip;
The cleaning liquid pool, the cleaning liquid channel, the liquid pool to be tested, the liquid channel to be tested and the ventilation channel are all separated from the bottom plate layer.
2. the centrifugal microfluidic test strip chip according to claim 1, wherein the nitrocellulose membrane of the chromatographic test strip is disposed corresponding to the detection zone through hole and the visible window; the sample pad of the chromatography test strip is arranged corresponding to the sample injection pool.
3. A centrifugal microfluidic test paper chip according to claim 2, wherein the visible window is an open-type through hole.
4. A centrifugal microfluidic test strip chip according to claim 2, wherein the cross-sections of said cover plate layer, said channel layer and said base plate layer are the same, and the cross-sectional shapes include but are not limited to rectangles.
5. A centrifugal microfluidic test strip chip according to claim 1, wherein the shape of said cleaning liquid channel includes but is not limited to wave shape.
6. A centrifugal microfluidic test strip chip according to claim 1, wherein the shape of said vent channel includes but is not limited to a zigzag shape.
7. the centrifugal microfluidic test paper chip of claim 1, wherein the cover chip fixing holes are identical in shape to the channel chip fixing holes and the base chip fixing holes and are arranged in a superposed manner to form chip fixing holes penetrating through the centrifugal microfluidic test paper chip.
8. The centrifugal microfluidic test paper chip of claim 1, wherein the cleaning solution pool and the solution pool to be tested are both located on one side of the sample feeding pool close to the channel chip fixing hole.
9. The centrifugal microfluidic test paper chip of claim 1, wherein in the channel layer, the detection area through hole, the cleaning solution pool, the cleaning solution channel, the liquid pool to be tested, the ventilation channel, the liquid channel to be tested and the sample injection pool are sequentially arranged on one side of the channel chip fixing hole from near to far.
10. a centrifugal microfluidic test strip chip according to claim 1, wherein the driving force for the liquid in the centrifugal microfluidic test strip chip is centrifugal force.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920325176.2U CN209772148U (en) | 2019-03-14 | 2019-03-14 | Centrifugal micro-fluidic test paper chip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920325176.2U CN209772148U (en) | 2019-03-14 | 2019-03-14 | Centrifugal micro-fluidic test paper chip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209772148U true CN209772148U (en) | 2019-12-13 |
Family
ID=68797776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920325176.2U Active CN209772148U (en) | 2019-03-14 | 2019-03-14 | Centrifugal micro-fluidic test paper chip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209772148U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102022106693B3 (en) | 2022-03-22 | 2023-03-16 | Dermagnostix GmbH | Centrifugal Microfluidic Biochip |
-
2019
- 2019-03-14 CN CN201920325176.2U patent/CN209772148U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102022106693B3 (en) | 2022-03-22 | 2023-03-16 | Dermagnostix GmbH | Centrifugal Microfluidic Biochip |
| WO2023179810A1 (en) | 2022-03-22 | 2023-09-28 | Dermagnostix GmbH | Centrifugal microfluidic biochip |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4571129B2 (en) | Method for uniformly applying fluid to reaction reagent area | |
| US4918025A (en) | Self contained immunoassay element | |
| JP4869602B2 (en) | Method and apparatus for dividing a specimen into multiple channels of a microfluidic device | |
| JP4707035B2 (en) | Mixing in microfluidic devices | |
| EP3194965B1 (en) | Lateral flow assay device | |
| CN106053859B (en) | A kind of centrifugal glycosylated hemoglobin detection micro-fluidic chip | |
| KR0182619B1 (en) | Embedded Assay Assembly and Apparatus | |
| EP2777499B1 (en) | Rotatable fluid sample collection device | |
| US20210268496A1 (en) | Lateral-flow assay device with filtration flow control | |
| JP2010505108A (en) | Cartridge system | |
| JP2007502979A5 (en) | ||
| CN101021530B (en) | Automatic channel resolution chemiluminescent multicomponent immunodetection system and analytical method | |
| CN109765391B (en) | Multi-index detection centrifugal test strip chip | |
| CN109759155A (en) | A kind of multiple determination centrifugal type microfludic chip | |
| WO2016161430A1 (en) | Three-dimensional microfluidic devices with pop-up feature | |
| CN209772148U (en) | Centrifugal micro-fluidic test paper chip | |
| CN209772147U (en) | Centrifugal micro-fluidic chip | |
| CN111077325A (en) | Microporous membrane interception and aggregation biochemical detection device and detection method thereof | |
| CN209680127U (en) | A kind of multiple determination centrifugal type microfludic test paper chip | |
| TWI295730B (en) | Microfluidic chip for sample assay and method thereof | |
| CN209680126U (en) | A kind of multiple determination centrifugal type microfludic chip | |
| JPH0961312A (en) | Simplified measuring device | |
| CN109759156A (en) | A kind of centrifugal type microfludic chip | |
| CN210045262U (en) | Cardiovascular emergency detection micro-fluidic chip | |
| CN115598351A (en) | Microfluidic autoantibody immunoassay chip |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |