CN209745816U - breathing type reagent tube for rapid free radical detector - Google Patents
breathing type reagent tube for rapid free radical detector Download PDFInfo
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- CN209745816U CN209745816U CN201920444748.9U CN201920444748U CN209745816U CN 209745816 U CN209745816 U CN 209745816U CN 201920444748 U CN201920444748 U CN 201920444748U CN 209745816 U CN209745816 U CN 209745816U
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Abstract
The utility model discloses a quick free radical detector reagent pipe of formula of breathing, including black tube, reagent ampoule, the mouth of blowing has been seted up to black tube upper end, the tube opening has been seted up to black tube bottom, black tube both sides below is provided with the reagent and holds between the fingers the explosion point, arc notch has been seted up to black tube front end center department, arc notch department is provided with air flow controller, the venthole has been seted up to the top that black tube front end is close to the arc notch, tube opening part joint has transparent lens, transparent lens upper end one side is provided with little filter core No. one, the inside vertical welding of black tube has the baffle. The reagent tube of the respiratory type rapid free radical detector is different from the traditional TBARS blood and urine detection and the like, and the reagent tube of the respiratory type rapid free radical detector is more convenient, rapid and noninvasive to collect the human free radical markers and can accurately detect and evaluate the level of the human free radicals.
Description
Technical Field
The utility model relates to a reagent pipe specifically is a quick free radical detector of formula of respiration reagent pipe.
Background
When the covalent bond between chemical entities is broken, one of the electrons remains, and an atom is newly formed, then radicals are very likely to form. Free radicals have a very high reactivity in view of the presence of lone electrons. Cell membranes and Low Density Lipoproteins (LDL) are rich in polyunsaturated fatty acids (PUFA). Polyunsaturated fatty acids make the cell membrane mobile. Free radicals in particular tend to attack cells, abstracting electrons from their plasma membrane, which is known as lipid peroxidation. The active oxygen targets the carbon-carbon double bond of the polyunsaturated fatty acid. Since the carbon-carbon double bond weakens the carbon-carbon single bond, this allows the radical to easily dissociate the carbon-hydrogen bond. The radical will abstract a single electron from the hydrogen atom associated with the carbon atom at the position of the double bond. A lone electron is then left on the carbon atom, which in turn forms a free radical. In an effort to stabilize carbon-centered radicals, molecules undergo rearrangement. The new aligned molecule is called Conjugated Diene (CD). The conjugated diene is very easy to react with oxygen to form peroxy radical. The peroxy radical then abstracts an electron from another lipid molecule during amplification. This process continues in the following chain reaction. When fatty acids are peroxidized, they decompose into aldehydes which are then excreted. Aldehydes such as thiobarbituric acid reactant (TBARS) have been widely used as general markers for free radical products. The longest measured TBARS is Malondialdehyde (MDA). The reaction between Malondialdehyde (MDA) and thiobarbituric acid (TBA) or its diethyl derivative has been widely used to evaluate lipid peroxidation of biological materials. The reaction produced a red MDA-TBA adduct, 2mol TBA plus 1mol MDA. The visible absorbance of the colored complex (. lamda.max 532nm) can be quantified using a spectrophotometer.
Traditional TBARS blood and urine detection and the like are inconvenient, have low detection speed and can not accurately detect and evaluate the level of free radicals in a human body. Therefore, a respiratory type fast free radical detector reagent tube is provided by those skilled in the art to solve the problems mentioned in the background art.
Disclosure of Invention
An object of the utility model is to provide a formula of breathing quick free radical detector reagent pipe to solve the problem that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme:
A reagent tube of a respiratory type rapid free radical detector comprises a black tube shell and a reagent ampoule bottle, wherein the upper end of the black tube shell is provided with an air blowing port, the bottom end of the black tube shell is provided with a tube shell opening, reagent pinch-off points are arranged below the two sides of the black tube shell, an arc-shaped notch is arranged at the center of the front end of the black tube shell, an air flow controller is arranged at the arc-shaped notch, an air outlet hole is arranged at the front end of the black tube shell and above the arc-shaped notch, a transparent lens is clamped at the opening of the tube shell, a small filter element is arranged on one side of the upper end of the transparent lens, a baffle is vertically welded inside the black tube shell, the inside air flow controller that is close to of baffle one side has seted up the joint mouth, the inside top of black tube is close to baffle one side and inlays and have No. two little filter cores, the inside below of black tube is located reagent and holds between the fingers explosion point department and places the reagent ampoule.
As a further aspect of the present invention: the air flow controller comprises exhaust holes, clamping pins, AFR caps and steel balls, the air flow controller is made of transparent plastic pipes, the exhaust holes are formed in the upper end and the lower end of the air flow controller, the clamping pins are fixed on the inner side of the air flow controller, the AFR caps are clamped at the upper end of the inner portion of the air flow controller, and the steel balls are placed in a cavity of the inner portion of the air flow controller.
As a further aspect of the present invention: the reagent ampoule is glass bottle material, the reagent ampoule is microparticle catalysis biosensing free radical and detects sensitization powder ampoule reagent, reagent ampoule thickness is 0.2mm-0.3 mm.
As a further aspect of the present invention: the air flow controller is mutually limited and clamped with the baffle through the clamping pin and the clamping interface.
As a further aspect of the present invention: the first small filter element and the second small filter element are both made of PET polyester staple fiber small filter elements and are D-shaped.
As a further aspect of the present invention: the black pipe shell is in an oval shape.
Compared with the prior art, the beneficial effects of the utility model are that:
The reagent tube of the respiratory type rapid free radical detector is different from the traditional TBARS blood and urine detection and the like, and the reagent tube of the respiratory type rapid free radical detector is more convenient, rapid and noninvasive to collect markers of the free radicals of the human body, and can accurately detect and evaluate the level of the free radicals of the human body.
Drawings
Fig. 1 is a schematic structural diagram of a reagent tube of a respiratory type rapid free radical detector.
FIG. 2 is a schematic view of an arc-shaped notch in a reagent tube of a respiratory fast free radical detector.
FIG. 3 is an exploded view of a reagent tube of a respiratory fast free radical detector.
FIG. 4 is a schematic diagram of an air flow controller in a reagent tube of a respiratory fast free radical detector.
FIG. 5 is a top view of a transparent lens of a reagent tube of a respiratory fast free radical detector.
In the figure: 1. a black cartridge; 101. a card interface; 2. an air blowing port; 3. a reagent pinch point; 4. an arc-shaped notch; 5. an air flow controller; 501. an exhaust hole; 502. a bayonet lock; 503. an AFR cap; 504. steel balls; 6. the pipe shell is opened; 7. an air outlet; 8. a transparent lens; 9. a first small filter element; 10. a second small filter element; 11. reagent ampoule bottle.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-5, in the embodiment of the present invention, a reagent tube for a respiratory type fast free radical detector comprises a black tube shell 1 and a reagent ampoule bottle 11, wherein an air blowing port 2 is formed at the upper end of the black tube shell 1, a tube shell opening 6 is formed at the bottom end of the black tube shell 1, a reagent pinch point 3 is arranged below two sides of the black tube shell 1, an arc-shaped notch 4 is formed at the center of the front end of the black tube shell 1, an air flow controller 5 is arranged at the arc-shaped notch 4, an air outlet 7 is formed at the front end of the black tube shell 1 near the arc-shaped notch 4, a transparent lens 8 is clamped at the tube shell opening 6, a first small filter element 9 is arranged at one side of the upper end of the transparent lens 8, a baffle is vertically welded inside the black tube shell 1, a clamping port 101 is formed at one side of the baffle inside, which is close to the air flow controller 5, and, and a reagent ampoule bottle 11 is arranged at a reagent pinch-off point 3 at the lower part in the black tube shell 1.
the air flow controller 5 comprises an exhaust hole 501, a bayonet 502, an AFR (atomic frequency range) cap 503 and a steel ball 504, the air flow controller 5 is made of a transparent plastic tube, the exhaust hole 501 is formed in the upper end and the lower end of the air flow controller 5, the bayonet 502 is fixed on the inner side of the air flow controller 5, the AFR cap 503 is clamped at the upper end of the inner part of the air flow controller 5, and the steel ball 504 is placed in the inner cavity of the air flow controller 5.
Reagent ampoule 11 is the glass bottle material, reagent ampoule 11 is microparticle catalysis biosensing free radical detection sensitization powder ampoule, reagent ampoule 11 thickness is 0.2mm-0.3 mm.
The air flow controller 5 is mutually limited and clamped with the baffle through a clamping pin 502 and a clamping interface 101.
The first small filter element 9 and the second small filter element 10 are both made of PET polyester fiber short fiber small filter elements and are D-shaped.
The black cartridge 1 is oval in shape.
The utility model discloses a theory of operation is:
The assembly process of each component of the reagent tube of the respiratory type rapid free radical detector comprises the following steps:
First, a black case 1 is prepared.
And secondly, a small filter element 10 of the second number is plugged into the black tube shell 1.
And thirdly, placing the mixture into a reagent ampoule bottle 11.
And fourthly, the air flow controller 5 is placed in and fixed in the black tube shell 1 through clamping of the clamping pin 502 and the clamping interface 101.
And fifthly, plugging the small filter element 9 into the transparent lens 8.
And sixthly, finally, inserting the transparent lens 8 into the opening 6 of the cartridge, thereby completing the installation.
The use flow is as follows:
After the user eats or drinks water, the test can be started after waiting 15 minutes.
step one, holding the black tube shell 1 with the air blowing port 2 upward, squeezing the appointed reagent pinching and explosion point 3 by a thumb and a forefinger, and pinching and exploding the reagent ampoule bottle 11 inside.
And step two, the black tube shell 1 is held with the air blowing port 2 vertically upward, and the reagent tube is flicked by fingers for multiple times to ensure that the yellow reagent powder is uniformly distributed on the transparent lens 8 at the bottom of the reagent tube.
And step three, air blowing is started by aligning the air blowing port 2, the air blowing strength is preferably that the steel balls in the air flow controller are suspended in the red mark area, and the steel balls which exceed the red mark area close the air outlet hole of the air flow controller, which indicates that the air blowing strength is overlarge.
And step four, keeping the air blowing opening 2 of the reagent pipe upward, and rapidly shaking up and down for 5 seconds with force to fully mix and react the exhaled air with the reagent powder.
And fifthly, holding the reagent tube with the air blowing hole 2 vertically upward, and flicking the reagent tube by fingers for multiple times to ensure that the reagent powder is uniformly distributed on the transparent lens 8 at the bottom of the reagent tube.
And step six, inserting the reagent tube into the OXI-CHECKER free radical detector, aligning a positioning pin on the side surface of the reagent tube to the mark of an insertion hole positioning slot of the detector during insertion, inserting the reagent tube in a correct direction, starting detection after insertion, and waiting for a detection result.
the detection principle of the reagent tube of the respiratory fast free radical detector is that when a subject blows air towards the reagent tube of the free radical detector, condensate in exhaled air can permeate into self-made and developed micro-particle catalytic biosensing photosensitive powder reagent (hereinafter referred to as reagent) encapsulated in the tube, the reagent can react with free radical markers (aldehydes, hydrogen peroxide and superoxide) in the exhaled air to change the color of the reagent from yellow to pink, pink purple, purple and the like, and the level of free radicals of a human body can be analyzed by using a special OXI-CHECKER respiratory fast free radical detector of Ekex biotechnology Limited company in Shenzhen city.
The opening diameter of the air outlet 7 is 1 mm-2.5 mm.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.
Claims (6)
1. A breathing type reagent tube for a rapid free radical detector comprises a black tube shell (1) and a reagent ampoule bottle (11), and is characterized in that an air blowing port (2) is formed in the upper end of the black tube shell (1), a tube opening (6) is formed in the bottom end of the black tube shell (1), reagent explosion points (3) are arranged below two sides of the black tube shell (1), an arc-shaped notch (4) is formed in the center of the front end of the black tube shell (1), an air flow controller (5) is arranged at the arc-shaped notch (4), an air outlet hole (7) is formed in the front end of the black tube shell (1) and close to the upper part of the arc-shaped notch (4), a transparent lens (8) is clamped at the tube opening (6), a small filter element (9) is arranged on one side of the upper end of the transparent lens (8), and a baffle is vertically welded inside the, the utility model discloses a reagent ampoule bottle, including baffle, black tube shell (1), baffle inside is close to air flow controller (5) one side and has seted up joint interface (101), black tube shell (1) inside top is close to baffle one side and inlays and have No. two little filter cores (10), reagent ampoule bottle (11) have been placed to black tube shell (1) inside below is located reagent and holds between the fingers explosion point (3) department.
2. The reagent tube of the respiratory type rapid free radical detector of claim 1, wherein the air flow controller (5) comprises an exhaust hole (501), a bayonet lock (502), an AFR cap (503) and a steel ball (504), the air flow controller (5) is made of a transparent plastic tube, the exhaust hole (501) is arranged at the upper end and the lower end of the air flow controller (5), the bayonet lock (502) is fixed at the inner side of the air flow controller (5), the AFR cap (503) is clamped at the inner upper end of the air flow controller (5), and the steel ball (504) is arranged in the inner cavity of the air flow controller (5).
3. The breathing type reagent tube for a rapid free radical detector according to claim 1, wherein the reagent ampoule bottle (11) is made of glass, the reagent ampoule bottle (11) is a photosensitive powder ampoule reagent for sensing free radical in the detection of the micro-particle catalytic biological sensing, and the thickness of the reagent ampoule bottle (11) is 0.2mm-0.3 mm.
4. The reagent tube of the respiratory type rapid free radical detector of claim 1, wherein the air flow controller (5) is clamped with the baffle plate by a clamping pin (502) and a clamping interface (101) in a limiting manner.
5. The reagent tube of a respiratory type rapid free radical detector according to claim 1, wherein the first small filter element (9) and the second small filter element (10) are both made of PET polyester fiber short fiber small filter element material and have D-shaped shapes.
6. A respiratory fast radical detector reagent tube according to claim 1, characterized in that the black cartridge (1) is oval in shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920444748.9U CN209745816U (en) | 2019-04-03 | 2019-04-03 | breathing type reagent tube for rapid free radical detector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920444748.9U CN209745816U (en) | 2019-04-03 | 2019-04-03 | breathing type reagent tube for rapid free radical detector |
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| Publication Number | Publication Date |
|---|---|
| CN209745816U true CN209745816U (en) | 2019-12-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920444748.9U Active CN209745816U (en) | 2019-04-03 | 2019-04-03 | breathing type reagent tube for rapid free radical detector |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109884046A (en) * | 2019-04-03 | 2019-06-14 | 深圳市埃克斯生物科技有限公司 | A kind of rapid detection method of type of respiration acquisition free radical marker |
| TWI730704B (en) * | 2020-03-31 | 2021-06-11 | 普元生技股份有限公司 | Breathing air flow detecting device for a nebulizing device |
-
2019
- 2019-04-03 CN CN201920444748.9U patent/CN209745816U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109884046A (en) * | 2019-04-03 | 2019-06-14 | 深圳市埃克斯生物科技有限公司 | A kind of rapid detection method of type of respiration acquisition free radical marker |
| TWI730704B (en) * | 2020-03-31 | 2021-06-11 | 普元生技股份有限公司 | Breathing air flow detecting device for a nebulizing device |
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