CN209656670U - A kind of dissolution testing apparatus of digestive ferment - Google Patents

Abstract

The utility model discloses a kind of dissolution testing apparatus of digestive ferment, including placement rack, the top exterior walls of the placement rack offer the placing groove equidistantly distributed, and the circumferential inner wall of placing groove is equipped with fixed ring by bolt, the circumferential inner wall of the fixed ring is equipped with placing tube by bearing, and the inside of placing tube is placed with admission extinguisher, the top exterior walls of the placing tube offer link slot, and admission extinguisher position corresponding with link slot is welded with fixture block, the middle position of the placing groove bottom interior wall offers fixation hole.The utility model is connected admission extinguisher with placing tube with link slot by link block, to improve the stability between admission extinguisher and placing tube, pass through rubber pad increasing friction force between sealing block and admission extinguisher, improve stability fixed between sealing block and admission extinguisher, to improve the stability of the container when dissolving out operation, it avoids the fluctuation of water flow that container is caused to shake, prevents the accuracy for influencing to measure.

Description

A kind of dissolution testing apparatus of digestive ferment

Technical field

The utility model relates to medical research and development technology field more particularly to a kind of dissolution testing apparatus of digestive ferment.

Background technique

Medicine is the substance or preparation of prevention or treatment or diagnosing human and livestock disease, and drug by sources divides natural drug And synthetic drug, medical also preventable disease, or enhancing body are to the resistance of disease or the substance of assisted diagnosis disease, medicine The research aiming at pharmaceutical substance is researched and developed, digestive ferment belongs to one kind of the common substance of medicine, is generally stored in capsule and carries out It uses.

It in R&D process, often needs to be measured its dissolution rate, dissolution rate refers to drug from tablet or capsule etc. Tablet or capsule are generally added in container by the speed and degree that solid pharmaceutical preparation dissolves out in regulation solvent, continuous mode In solvent, container is placed under certain temperature environment by water-bath, and so that it is carried out dissolution operation with corresponding speed rotary container, Sample is extracted again to be detected, but in practical measurement process, container outer wall is directly contacted with water, since the flowing of water can make It is shaken at container, will affect the accuracy of determination data.

Utility model content

Purpose of the utility model is to solve disadvantages existing in the prior art, and a kind of digestive ferment proposed is molten Out-degree measurement device.

To achieve the goals above, the utility model adopts the technical scheme that

A kind of dissolution testing apparatus of digestive ferment, including placement rack, the top exterior walls of the placement rack offer equidistantly Placing groove from distribution, and the circumferential inner wall of placing groove is equipped with fixed ring by bolt, the circumferential inner wall of the fixed ring is logical It crosses bearing and placing tube is installed, and the inside of placing tube is placed with admission extinguisher, the top exterior walls of the placing tube offer connection Slot, and admission extinguisher position corresponding with link slot is welded with fixture block, the middle position of the placing groove bottom interior wall offers solid Determine hole, and the circumferential inner wall of fixation hole is equipped with the connecting rod placed vertically by bearing, the top outer wall of connecting rod passes through spiral shell The connection of the bottom outer wall of bolt and placing tube, the bottom outer wall of the placement rack are equipped with base box, and base box bottom by bolt Inner wall position corresponding with placing groove in portion's is equipped with driving motor by bolt, and the output shaft of driving motor passes through shaft coupling and company Extension bar connection.

Preferably, the both ends of placement rack outer circumferential walls two sides pass through bolt and are equipped with the electric expansion placed vertically Bar, and the top outer wall of four electric telescopic rods is equipped with the same horizontal positioned top plate by bolt.

Preferably, the bottom of the top plate is provided with cover board, and cover board top exterior walls position corresponding with admission extinguisher opens up There is mounting hole, the circumferential inner wall of mounting hole is equipped with sealing block by bearing.

Preferably, sealing block bottom outer wall position corresponding with admission extinguisher offers auxiliary tank, and the top of auxiliary tank Portion's inner wall is bonded with rubber pad, and the bottom outer wall of rubber pad and the top exterior walls of admission extinguisher are abutted against.

Preferably, the top exterior walls of the sealing block offer via hole, and the circumferential inner wall of via hole is pacified by bearing It equipped with link block, is connected between the top exterior walls of link block and the bottom outer wall of top plate, the top exterior walls of link block detachably connect It is connected to probe tube.

Preferably, the outer circumferential walls of the placing tube offer the groove equidistantly distributed.

Preferably, the bottom of placement rack outer circumferential walls side is equipped with water inlet pipe, and placement rack circumference by bolt A lateral roof of the outer wall far from water inlet pipe is equipped with outlet pipe by bolt, offers connecting hole between two neighboring placing groove.

The utility model has the following beneficial effects:

1, when using the device, admission extinguisher is placed in placing tube, solvent and capsule are added in admission extinguisher, benefit Cover board is fallen to be pressed and be fixed by admission extinguisher using sealing block with electric telescopic rod, makes placing groove using water inlet pipe and outlet pipe The water of interior circulation preference temperature rotates placing tube using driving motor to carry out dissolution operation, and placing tube is by bearing and places Fixed ring connection in slot, improves the stability between placing tube and placing groove, passes through ring junction between admission extinguisher and placing tube The fixture block and link slot of structure are connected and fixed, so that the stability between admission extinguisher and placing tube is improved, sealing block and storage By rubber pad increasing friction force between cylinder, stability fixed between sealing block and admission extinguisher is improved, is being dissolved out to improve The stability of container when operation, avoids the fluctuation of water flow that container is caused to shake, and prevents the accuracy for influencing to measure.

2, it can be placed with the admission extinguisher equidistantly distributed on placement rack, and rotated using different driving motors, from And the admission extinguisher containing different solvents is rotated using same rotational speed, the storage containing same solvent is rotated using different rotating speeds Cylinder goes up and down cover board using electric telescopic rod to compare measurement, and easy to use, probe tube is fixed on link block, even Block is connect to connect by bearing with sealing block, so that probe tube is kept fixed during rotating admission extinguisher, it is convenient in a timing Between after be quickly sampled measurement, further enhance the accuracy of measurement.

3, admission extinguisher and placing tube are all made of Heat Conduction Material, and the arc equidistantly distributed is offered in the outer wall of placing tube Groove improves the heat exchange effect of admission extinguisher and water, guarantees the effect of water-bath to increase the contact area for placing drum outer wall and water Fruit.

Detailed description of the invention

Fig. 1 be the utility model proposes a kind of digestive ferment dissolution testing apparatus overall structure diagram；

Fig. 2 be the utility model proposes a kind of digestive ferment dissolution testing apparatus partial enlargement structural representation；

Fig. 3 be the utility model proposes a kind of digestive ferment dissolution testing apparatus placement rack plan structure signal Figure；

In figure: 1 placement rack, 2 placing grooves, 3 fixed rings, 4 placing tubes, 5 admission extinguishers, 6 fixture blocks, 7 link slots, 8 base boxes, 9 Connecting rod, 10 driving motors, 11 electric telescopic rods, 12 top plates, 13 cover boards, 14 sealing blocks, 15 rubber pads, 16 fixture blocks, 17 samplings Pipe, 18 grooves, 19 connecting holes, 20 water inlet pipes, 21 outlet pipes.

Specific embodiment

The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.

Referring to Fig.1-3, a kind of dissolution testing apparatus of digestive ferment, including placement rack 1, the top exterior walls of placement rack 1 are opened Equipped with the placing groove 2 equidistantly distributed, and the circumferential inner wall of placing groove 2 is equipped with fixed ring 3, the circle of fixed ring 3 by bolt All inner walls are equipped with the placing tube 4 placed vertically by bearing, and the inside of placing tube 4 is placed with admission extinguisher 5, placing tube 4 Top exterior walls offer the link slot 7 of cyclic structure, and the position corresponding with link slot 7 of admission extinguisher 5 is welded with ring structure The cross section of fixture block 6, fixture block 6 is triangle, and is matched between fixture block 6 and link slot 7, the centre of 2 bottom interior wall of placing groove Position offers fixation hole, and the circumferential inner wall of fixation hole is equipped with the connecting rod 9 placed vertically by bearing, connecting rod 9 Top outer wall is connect by bolt with the bottom outer wall of placing tube 4, and the bottom outer wall of placement rack 1 is equipped with base box by bolt 8, and 8 bottom interior wall of base box position corresponding with placing groove 2 is equipped with driving motor 10 by bolt, driving motor 10 it is defeated Shaft is connect by shaft coupling with connecting rod 9.

In the utility model, the both ends of 1 outer circumferential walls two sides of placement rack pass through bolt be equipped with place vertically it is electronic Telescopic rod 11, and the top outer wall of four electric telescopic rods 11 is equipped with the same horizontal positioned top plate 12 by bolt, top The bottom of plate 12 is provided with horizontal positioned cover board 13, and 13 top exterior walls of cover board position corresponding with admission extinguisher 5 offers peace Hole is filled, the circumferential inner wall of mounting hole is equipped with sealing block 14,14 bottom outer wall of sealing block position corresponding with admission extinguisher 5 by bearing Setting and offering cross section is circular auxiliary tank, and the top inner wall of auxiliary tank is bonded with rubber pad 15, the bottom of rubber pad 15 The top exterior walls of outer wall and admission extinguisher 5 are abutted against, and the top exterior walls of sealing block 14 offer via hole, and the circumferential inner wall of via hole Link block 16 is installed by bearing, the top exterior walls of link block 16 are connect with the bottom outer wall of top plate 12 by bolt, connected The top exterior walls of block 16 offer perforation, and the circumferential inner wall of perforation is equipped with probe tube 17 by bolt；

The outer circumferential walls of placing tube 4 offer the groove 18 equidistantly distributed, and the arc-shaped structure of groove 18, placement rack 1 The bottom of outer circumferential walls side is equipped with water inlet pipe 20, and side of 1 outer circumferential walls of placement rack far from water inlet pipe 20 by bolt Top is equipped with outlet pipe 21 by bolt, and connecting hole 19, placing groove 2 and connecting hole are offered between two neighboring placing groove 2 19 constitute constant temperature chamber, and constant temperature chamber is connect with water inlet pipe 20 and outlet pipe 21.

Working principle: when using the device, admission extinguisher 5 is placed in placing tube 4, solvent and capsule are added to receipts It receives in cylinder 5, cover board 13 is fallen to be pressed and be fixed by admission extinguisher 5 using sealing block 14 using electric telescopic rod 11, utilizes water inlet Pipe 20 and outlet pipe 21 make the water of circulation preference temperature in placing groove 2, utilize the arc groove equidistantly distributed outside placing tube 4 18 improve heat exchange effect, rotate placing tube 4 using driving motor 10 to carry out dissolution operation, placing tube 4 passes through bearing and puts The fixed ring 3 set in slot 2 connects, and improves the stability between placing tube 4 and placing groove 2, leads between admission extinguisher 5 and placing tube 4 The fixture block 6 and link slot 7 for crossing ring structure are connected and fixed, so that the stability between admission extinguisher 5 and placing tube 4 is improved, Fixed stability is improved between sealing block 14 and admission extinguisher 5 using rubber pad 15, to improve container when dissolving out operation Stability prevents the accuracy for influencing to measure, and probe tube 17 is fixed on link block 16, and link block 16 passes through bearing and sealing block 14 connections, to make probe tube 17 be kept fixed during rotating admission extinguisher 5, it is convenient dissolution after a certain period of time quickly into Row is measured by sampling, and further enhances the accuracy of measurement.

The preferable specific embodiment of the above, only the utility model, but the protection scope of the utility model is not It is confined to this, anyone skilled in the art is within the technical scope disclosed by the utility model, practical according to this Novel technical solution and its utility model design are subject to equivalent substitution or change, should all cover the protection model in the utility model Within enclosing.

Claims (7)

1. a kind of dissolution testing apparatus of digestive ferment, including placement rack (1), which is characterized in that the top of the placement rack (1) Outer wall offers the placing groove (2) equidistantly distributed, and the circumferential inner wall of placing groove (2) is equipped with fixed ring (3) by bolt, The circumferential inner wall of the fixed ring (3) is equipped with placing tube (4) by bearing, and the inside of placing tube (4) is placed with admission extinguisher (5), the top exterior walls of the placing tube (4) offer link slot (7), and admission extinguisher (5) position weldering corresponding with link slot (7) It is connected to fixture block (6), the middle position of placing groove (2) bottom interior wall offers fixation hole, and the circumferential inner wall of fixation hole is logical It crosses bearing and the connecting rod (9) placed vertically is installed, the top outer wall of connecting rod (9) passes through the bottom of bolt and placing tube (4) Outer wall connection, the bottom outer wall of the placement rack (1) is equipped with base box (8) by bolt, and base box (8) bottom interior wall and The corresponding position of placing groove (2) is equipped with driving motor (10) by bolt, and the output shaft of driving motor (10) passes through shaft coupling It is connect with connecting rod (9).

2. a kind of dissolution testing apparatus of digestive ferment according to claim 1, which is characterized in that the placement rack (1) The both ends of outer circumferential walls two sides pass through bolt and are equipped with the electric telescopic rod (11) placed vertically, and four electric telescopic rods (11) top outer wall is equipped with the same horizontal positioned top plate (12) by bolt.

3. a kind of dissolution testing apparatus of digestive ferment according to claim 2, which is characterized in that the top plate (12) Bottom is provided with cover board (13), and cover board (13) top exterior walls position corresponding with admission extinguisher (5) offers mounting hole, mounting hole Circumferential inner wall sealing block (14) are equipped with by bearing.

4. a kind of dissolution testing apparatus of digestive ferment according to claim 3, which is characterized in that the sealing block (14) Bottom outer wall position corresponding with admission extinguisher (5) offers auxiliary tank, and the top inner wall of auxiliary tank is bonded with rubber pad (15), The bottom outer wall of rubber pad (15) and the top exterior walls of admission extinguisher (5) are abutted against.

5. a kind of dissolution testing apparatus of digestive ferment according to claim 4, which is characterized in that the sealing block (14) Top exterior walls offer via hole, and the circumferential inner wall of via hole is equipped with link block (16) by bearing, link block (16) Top exterior walls and top plate (12) bottom outer wall between connect, the top exterior walls of link block (16) are removably connected with probe tube (17)。

6. a kind of dissolution testing apparatus of digestive ferment according to claim 5, which is characterized in that the placing tube (4) Outer circumferential walls offer the groove (18) equidistantly distributed.

7. a kind of dissolution testing apparatus of digestive ferment according to claim 6, which is characterized in that the placement rack (1) The bottom of outer circumferential walls side is equipped with water inlet pipe (20) by bolt, and placement rack (1) outer circumferential walls are far from water inlet pipe (20) A lateral roof be equipped with outlet pipe (21) by bolt, offer connecting hole (19) between two neighboring placing groove (2).