CN209559726U - Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies - Google Patents

Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies Download PDF

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Publication number
CN209559726U
CN209559726U CN201822259745.6U CN201822259745U CN209559726U CN 209559726 U CN209559726 U CN 209559726U CN 201822259745 U CN201822259745 U CN 201822259745U CN 209559726 U CN209559726 U CN 209559726U
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China
Prior art keywords
connecting rod
meter
sample
computer
electrochemical workstation
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Expired - Fee Related
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CN201822259745.6U
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Chinese (zh)
Inventor
熊缨
朱涛
杨杰
沈永水
何留永
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Zhejiang University of Technology ZJUT
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Zhejiang University of Technology ZJUT
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Abstract

Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies is equipped with computer, electrochemical workstation, motor, sample slot, speed-regulating type peristaltic pump, thermostat on pedestal;Motor drives crank link mechanism by belt, pinion gear and gear wheel, and the end of crank link mechanism is fixedly connected with the upper end of oscillating rod, and the lower end of oscillating rod is equipped with sample, and oscillating rod is inserted into sample slot;Sample slot, speed-regulating type peristaltic pump, the reservoir connection in thermostat, form circulatory flow;First thermometer and pH meter, flow rate meter are housed on sample slot, second temperature meter is housed on reservoir;First thermometer connects computer with the data output end of pH meter, flow rate meter, second temperature meter;Motor, speed-regulating type peristaltic pump, thermostat control signal input connect computer;Electrode inside electrochemical workstation connection sample slot is connected with sample, electrochemical workstation and computer bidirectional data connection.

Description

Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies
Technical field
The utility model relates to a kind of devices of the medical material degradation property analysis under simulation human body environment, exactly It is the device of double acting state degradation property analysis outside a kind of medical magnesium alloy implantation material bodies.
Background technique
Magnesium and magnesium alloy are known as " 21 century green engineering material ", have excellent mechanics as structural metallic material Performance, while magnesium and magnesium alloy also possess unique biocompatibility and degradability, in the application of field of medical materials It receives significant attention, always is the hot spot that domestic and foreign scholars are studied as novel degradable medical embedded material.So And magnesium elements activity with higher, corrosion degradation easily occurs in aqueous solution or wet environment, therefore in human body acidic physiological Under environment, medical magnesium alloy implantation material is often just degraded before tissue recovery, is not able to satisfy and is implanted into material as human body Material necessary mechanics and morphology requirement in service phase, to increase the clinical application of medical magnesium alloy and widely used Difficulty.And the outer test method of medical magnesium alloy implantation material bodies compared to et al. Ke experiment have empirical factor controllability it is good, Test period is short, high sensitivity and it is low many advantages such as spend, therefore vast domestic and international researcher is all increased and is closed to medical magnesium The research of golden external corrosion degradation performance.But research multi-focus is tested in external static immersing at present, i.e., plants medical magnesium alloy Enter material and be placed on static immersing in simulated body fluid, studies the external degradation performance of magnesium alloy implant material according to this, but in this way Static immersing experiment cannot achieve the real simulation of particular surroundings in human body, have ignored isoperibol and body fluid flow in human body Dynamic, human organ displacement double dynamic environment influence the corrosion degradation of medical magnesium alloy implantation material, are unable to monitor body The variation of simulated body fluid temperature and pH value in outer Dynamic Corrosion degradation process;Meanwhile general external static immersing experiment is often Intuitive "ball-park" estimate, this kind of side will be carried out to its degradation rate using drying sample and the method weighed or liberation of hydrogen method Method process is cumbersome and there are certain errors can not accurately measure its degradation rate, also consumes a large amount of manpower and material resources.
Summary of the invention
The utility model overcomes the disadvantages mentioned above of the prior art, provides double acting state outside a kind of medical magnesium alloy implantation material bodies The device of degradation property analysis.
The device of double acting state degradation property analysis outside a kind of medical magnesium alloy implantation material bodies of the utility model, including bottom Seat 1, it is characterised in that: be equipped with computer 3, electrochemical workstation 25, motor 5, sample slot 27, speed-regulating type on pedestal 1 and wriggle Pump 34, thermostat 35;Motor 5 drives pinion gear 10 by belt 8, and pinion gear 10 is engaged with gear wheel 14, and gear wheel 14 connects The crank link mechanism being made of first connecting rod 18, second connecting rod 21, third connecting rod 23,18 one end of first connecting rod and gear wheel 14 On connecting rod link block 16 it is hinged, one end of the other end and third connecting rod 23 is hinged, and middle part and one end of second connecting rod 21 are hinged, The other end of second connecting rod 21 and the connecting rod shaft supporting frame 19 being fixed on pedestal 1 are hinged, the rectangular zigzag ruler shape of third connecting rod 23, The other end of third connecting rod 23 is fixedly connected with the upper end of oscillating rod 28, and the lower end of oscillating rod 28 is equipped with sample 29, and oscillating rod 28 is inserted Enter sample slot 27;Sample slot 27, speed-regulating type peristaltic pump 34, the reservoir 37 in thermostat 35 are connected to by liquid-transport pipe-line 26, shape At circulatory flow;
First thermometer 30 and pH meter 31, flow rate meter 32 are housed on sample slot 27, the second temperature is housed on reservoir 37 Degree meter 36;
First thermometer 30 connects computer with the data output end of pH meter 31, flow rate meter 32, second temperature meter 36 3;Motor 5, speed-regulating type peristaltic pump 34, thermostat 35 control signal input connect computer 3;
Electrochemical workstation 25 passes through the electrode 41 and sample 29 inside electrochemical workstation p-wire 42 and sample slot 27 Connection, electrochemical workstation 25 are connect by electrochemical workstation data line 43 with 3 bi-directional data of computer.
Further optimal technical scheme is as follows:
The motor is a kind of ac three-phase asynchronous motor of controllable rotating speed, can be connect with computer.
The electrochemical workstation is a kind of electrochemical workstation that is regulatable, can connecting computer.
The material of the liquid-transport pipe-line is a kind of glass of good thermal insulation property, inside be circular hole.
The sample slot is a kind of glass rectangular channel with thermal insulation property, and there are grooves for upper part, is all around deposited In connecting hole, there is also connecting holes above.
The oscillating rod top is wide and solid, and lower part is thin and light and handy, and its underpart has sample fixed structure.
The sample is medical magnesium alloy implantation material to be tested.
First thermometer and second temperature meter is the thermometer that can connect computer.
The pH meter is the pH meter that can connect computer.
The flow rate meter is a kind of flow rate meter of included display function.
The speed-regulating type peristaltic pump is a kind of adjustable speed, the peristaltic pump that can connect computer.
The thermostat is a kind of constant temperature water bath that can commonly connect computer.
The reservoir is a kind of glass rectangular channel that heat transfer property is fabulous, has preferable mechanical property and heat insulating ability Energy.
Control line, data line and the p-wire is data transmission and the control line that can connect computer.
The utility model realizes that medical magnesium closes by motor, belt, gear, crank link mechanism and computer synergy The controllable environment of the outer simulated human tissue organ movement of gold implantation material bodies, by speed-regulating type peristaltic pump, sample slot, thermostat, storage Liquid bath and liquid-transport pipe-line collective effect complete the outer constant temperature dynamic analog environment of medical magnesium alloy implantation material bodies, this double dynamic ring Border solve general external static immersing experiment without simulated body fluid dynamic circulation and simulated human tissue organ actual motion Problem, provides that simulated body fluid flow velocity is controllable and the experimental situation of human tissue organ's actual motion;Devise electrochemistry The mode of work station, thermometer, pH meter, flow rate meter and computer associated working completes medical magnesium alloy and is implanted into material bodies The real-time monitoring of temperature, pH, flow rate and various electrochemical datas during outer double acting state corrosion degradation is collected, and is utilized Processing software on computer is analyzed and processed collected data information, realizes the computer of double acting state corrosion degradation performance Analysis, and complete to drop its double Dynamic Corrosion by the electrochemical impedance spectrum analysis of computer software and the analysis of dynamic polarization curve Solve the analytical calculation of rate;Medical magnesium alloy, which is realized, by the collective effect of above-mentioned component is implanted into double dynamic degradations outside material bodies The function of performance evaluation is implanted into the external double acting state degradation property analysis and its solution of degradation rate of material for medical magnesium alloy A possibility that providing a kind of reliable and stable device, greatly improving magnesium alloy medical industrialization.
The utility model realizes that the real-time stabilization to motor speed controls by control manipulation of the computer to motor, then leads to Cross motor, belt, gear, the mating connection between crank link mechanism, realize the conversion and transmission of motor power, by power by Motor real-time stabilization is transferred to brace and connecting rod framework, then is transferred to oscillating rod by brace and connecting rod framework, realizes the examination on oscillating rod It is controllable to the movement of sample simulated human tissue organ to be finally completed computer for the movement of sample stable simulation human tissue organ Property;Speed-regulating type peristaltic pump, stablizing for thermostat are regulated and controled by computer, realize that the flow velocity of simulated body fluid is controllable in real time, simultaneously The temperature for completing simulated body fluid is constant, along with simulated body fluid is completed in the associated working of sample slot, reservoir and liquid-transport pipe-line Constant temperature adjustable speed environment;Pass through the connection work of thermometer, pH meter, flow rate meter and computer again, it is achievable to sample slot Interior simulated body fluid real time temperature and pH monitoring, while also its flow rate of real-time monitoring, also can be to the analogue body in reservoir The temperature of liquid carries out real time contrast, then is completed by the connection of electrochemical workstation and computer to the double acting state of sample in sample slot Various Electrochemistry Informations (electrochemical impedance spectroscopy and dynamic polarization curve etc.) analysis during corrosion degradation, realizes computer The timely analysis processing of real-time monitoring temperature, pH, flow velocity and Electrochemistry Information.
The utility model has the advantages that:
(1) connected by the cooperation between computer and motor, belt, gear, crank link mechanism, oscillating rod and sample It connects, provides the true environment of simulated human tissue organ movement in the external dynamic degradation experiment of medical magnesium alloy, reduce group Organ real motion environment is knitted to the error interference of experiment, greatly improves the accuracy of the present apparatus.
(2) it by regulation of the computer to speed-regulating type peristaltic pump, realizes the flow velocity of in-vitro simulated body fluid controllably and recycles Flowing, solving general external static immersing experiment, to ignore body fluid flow under truth dynamic to Corrosion Behaviors of Magnesium Alloys degradation property and speed The problem of rate influences increases the controllable demand of flow velocity of lower external Dynamic Corrosion degradation process experiment different in flow rate.
(3) by regulation of the computer to thermostat, the controllable function of isoperibol of external double dynamic analog body fluid is realized Can, reduce that general external static immersing experiment ignores human body isoperibol to Corrosion Behaviors of Magnesium Alloys degradation property and bring is missed Difference increases the measurement accuracy of device.
(4) thermometer, pH meter and flow rate meter are docked by computer, realizes the temperature of sample corrosion degradation process The real time monitoring of degree, pH and flow velocity, the effect of two thermometers is to increase temperature comparisons part, improve device stability and Controllability.
(5) by control of the computer to electrochemical workstation, electrochemical workstation is realized to the double Dynamic Corrosions of sample The real-time measurement of degradation data information improves the Accurate Analysis of corrosion degradation performance, can also save a large amount of manpowers and time.
(6) corrosion degradation data are analyzed using the data processing software on computer, utilizes electrochemical impedance spectroscopy It analyzes software and dynamic polarization curve analysis software carries out analytical calculation to its dynamic degradation rate indirectly, improve the present apparatus The completeness of performance evaluation increases the accuracy of device.
(7) whole device is combined closely with computer, there is higher the degree of automation, reduces the stupid of such previous device Principal characteristic provides a kind of completely new thinking for the design of such device instantly, increases the flexibility and applicability of device, save A large amount of manpower and material resources, widely available for the device provide a possibility that very big.
Detailed description of the invention
Fig. 1 is the plan view of utility model device.
Fig. 2 is the axonometric drawing of utility model device.
Fig. 3 is the axonometric drawing of another angle of utility model device.
Fig. 4 is the simulation human motion mechanism axonometric drawing of utility model device.
Fig. 5 is the third connecting rod 23 of the utility model and the axonometric drawing of oscillating rod 28.
Fig. 5 a is the portion the A enlarged drawing of Fig. 5.
Fig. 6 is the axonometric drawing of the sample slot of utility model device.
Fig. 7 is the schematic diagram of the flow channel for liquids of utility model device.
Fig. 8 is the schematic diagram of the liquid-transport pipe-line of utility model device.
Specific embodiment
With reference to the accompanying drawing, the technical solution of the utility model is further illustrated.
Referring to Fig. 1, Fig. 2, Fig. 3, description of symbols: pedestal 1, motor control line 2, computer 3, motor supporting base 4, electricity Machine 5, pulley 6, motor axle key 7, belt 8, pinion shaft support frame 9, pinion gear 10, pulley 11, pinion bearing 12, gear wheel Shaft supporting frame 13, gear wheel 14, gearwheel bearing 15, connecting rod link block 16, the first pin 17, first connecting rod 18, pitman shaft branch Support 19, the second pin 20, second connecting rod 21, third pin 22, third connecting rod 23, the 4th pin 24, electrochemical workstation 25, Liquid-transport pipe-line 26, sample slot 27, oscillating rod 28, sample 29, the first thermometer 30, pH meter 31, flow rate meter 32, sample slot branch Support seat 33, speed-regulating type peristaltic pump 34, thermostat 35, second temperature meter 36, reservoir 37, thermostat data line 38, thermometer and PH meter data line 39, speed-regulating type peristaltic pump data line 40, electrode 41, electrochemical workstation p-wire 42, electrochemical workstation number It is formed according to line 43.
The device of double acting state degradation property analysis outside a kind of medical magnesium alloy implantation material bodies of the utility model, including bottom Seat 1, it is characterised in that: be equipped with computer 3, electrochemical workstation 25, motor 5, sample slot 27, speed-regulating type on pedestal 1 and wriggle Pump 34, thermostat 35;Motor 5 drives pinion gear 10 by belt 8, and pinion gear 10 and gear wheel 14 are intermeshed, gear wheel 14 Connect the crank link mechanism that is made of first connecting rod 18, second connecting rod 21, third connecting rod 23,18 one end of first connecting rod passes through the One pin 17 and the connecting rod link block 16 on gear wheel 14 are hinged, and the other end passes through one end of third pin 22 and third connecting rod 23 Hingedly, middle part is hinged by one end of the second pin 20 and second connecting rod 21, and the other end of second connecting rod 21 passes through the 4th pin 24 is hinged with the connecting rod shaft supporting frame 19 that is fixed on pedestal 1, the rectangular zigzag ruler shape of third connecting rod 23, third connecting rod 23 it is another End is fixedly connected with the upper end of oscillating rod 28, and the lower end of oscillating rod 28 is equipped with sample 29, and oscillating rod 28 is inserted into sample slot 27;Sample slot 27, speed-regulating type peristaltic pump 34, the reservoir 37 in thermostat 35 are connected to by liquid-transport pipe-line 26, form circulatory flow;
First thermometer 30 and pH meter 31, flow rate meter 32 are housed on sample slot 27, the second temperature is housed on reservoir 37 Degree meter 36;
First thermometer 30 connects computer with the data output end of pH meter 31, flow rate meter 32, second temperature meter 36 3;Motor 5, speed-regulating type peristaltic pump 34, thermostat 35 control signal input connect computer 3;
Electrochemical workstation 25 passes through the electrode 41 and sample 29 inside electrochemical workstation p-wire 42 and sample slot 27 Connection, electrochemical workstation 25 are connect by electrochemical workstation data line 43 with 3 bi-directional data of computer.
Pedestal 1 is fixed on ground, can store all components of utility model device above.
Computer 3 passes through motor control line 2, electrochemical workstation data line 43, speed-regulating type peristaltic pump data line 40, constant temperature Slot data line 38 can be attached realization to motor 5, electrochemical workstation 25, speed-regulating type peristaltic pump 34, thermostat 35 respectively and adjust Control operation, is attached realization by thermometer and pH meter data line 39 and the first thermometer 30, pH meter 31, second temperature meter 36 Data acquisition and reception processing to temperature and pH.
Motor supporting base 4 is fixed on pedestal 1, and upper part is contacted with the fixation of motor 5, realizes the fixation of motor 5.
Motor 5 is the power resources of the present apparatus, connect and has cooperated with pulley 6, motor axle key 7, belt 8 by motor shaft At the conversion of output power, realize that motor power is spread out of to belt 8.
Pulley 6 is the part of motor shaft end, realizes connection cooperation by motor axle key 7 and motor 5.
Belt 8 is the transfer component of 5 power of motor outflow, is realized and is cooperated by pulley 6, motor axle key 7 and motor 5, connect The power and conversion for receiving motor 5 are gone out to pinion gear 10.
Pinion gear 10 supports pinion shaft to realize and is fixed on pedestal 1, passes through pinion gear by pinion shaft support frame 9 Bearing 12 and pinion shaft are fixed on one piece, and complete connection cooperation for belt 8 with belt 8 by the pulley 11 on pinion shaft Power transmission to pinion gear 10.
Gear wheel 14 supports Large Gear Shaft to realize and is fixed on pedestal 1, passes through canine tooth by Large Gear Shaft support frame 13 Wheel bearing 15 and Large Gear Shaft are fixed on one piece, and engage cooperation by the gear between pinion gear 10 and gear wheel 14 and complete gear Between power transmission.
Connecting rod link block 16 is fixed on gear wheel 14, and the synergy of connecting rod link block 16 and the first pin 17 is by canine tooth Wheel 14 is hinged with first connecting rod 18.
First connecting rod 18 is one of the connecting rod for simulating human motion, by connecting rod link block 16 and the first pin 17 and greatly Gear 14 is hinged, and that realizes the power of gear wheel 14 passes to first connecting rod 18.
Connecting rod shaft supporting frame 19 supports second connecting rod 21, hinged by the 4th pin 24 and second connecting rod 21.
Second connecting rod 21 is hinged with first connecting rod 18 by the second pin 20, and first connecting rod 18 passes through third pin 22 and the Three-link 23 is hinged.
Electrochemical workstation 25 is fixed on pedestal 1, inside electrochemical workstation p-wire 42 and sample slot 27 Electrode 41 and sample 29 realize connection, also pass through electrochemical workstation data line 43 and computer 3 and complete to connect.
Liquid-transport pipe-line 26 is the transmission pipeline of simulated body fluid, by pipeline and sample slot 27, speed-regulating type peristaltic pump 34 and Reservoir 37 is connected to.
Sample slot 27 is fixed on sample slot support base 33, can be realized by four holes all around and liquid-transport pipe-line 26 Connection, the groove and oscillating rod 28 reserved by top, which are realized, swings cooperation, and there is also the first thermometer 30 and pH meters 31 above Fixation position, it is internal that there is also the positions of flow rate meter 32.
Oscillating rod 28 is the critical component for simulating human motion, and upper part is fixedly connected with third connecting rod 23, and lower part exists The fixation clamping device of sample 29, also with 27 clearance fit of sample slot.
Sample 29 is the required sample to be tested of experiment, and the fixation with oscillating rod 28 is completed by the structure of 28 lower part of oscillating rod Connection.
First thermometer 30 is fixed on above sample slot 27, for monitoring the real time temperature of 27 internal simulation body fluid of sample slot , it is connected to by thermometer and pH meter data line 39 with computer 3.
PH meter 31 is fixed on above sample slot 27, for monitoring the real-time pH of sample slot 27 internal simulation body fluid, is led to Excess temperature meter and pH meter data line 39 are connected to computer 3.
Flow rate meter 32 is fixed on inside sample slot 27, for monitoring the real-time flow rate of 27 internal simulation body fluid of sample slot 's.
Speed-regulating type peristaltic pump 34 is the power resources of simulated body fluid, and bottom is fixed on above pedestal 1, and upper part passes through infusion Pipeline 26 is connected to sample slot 27, and lower part is connected to by liquid-transport pipe-line 26 with the reservoir 37 inside thermostat 35, also passes through tune Fast type peristaltic pump data line 40 is connected to the realization of computer 3.
Thermostat 35 is the thermostat of simulated body fluid, and bottom is fixed on pedestal 1, and there are reservoirs 37 for inside, also It is connected to by thermostat data line 38 with the realization of computer 3.
Second temperature meter 36 is placed in above thermostat 35, for monitoring the real time temperature variation of thermostat, passes through thermometer And pH meter data line 39 is connected to computer 3.
Reservoir 37 is fixed on inside thermostat 35, inside can place two liquid-transport pipe-lines 26.
Electrode 41 is used to be connected to the electrochemical workstation p-wire 42 above electrochemical workstation 25.
Since the foregoing is merely specific embodiment of the present utility model, but the protection of the utility model is without being limited thereto, Any those skilled in the art it is contemplated that the equivalent variation or substitution of the technical program technical characteristic, all covers Within the protection scope of the utility model.

Claims (1)

1. double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies, including pedestal (1), feature exists In: computer (3), electrochemical workstation (25), motor (5), sample slot (27), speed-regulating type peristaltic pump are installed on pedestal (1) (34), thermostat (35);Motor (5) drives pinion gear (10) by belt (8), and pinion gear (10) is engaged with gear wheel (14), The crank link mechanism that gear wheel (14) connection is made of first connecting rod (18), second connecting rod (21), third connecting rod (23), first Connecting rod link block (16) on connecting rod (18) one end and gear wheel (14) hingedly, cut with scissors by one end of the other end and third connecting rod (23) It connects, the one end at middle part and second connecting rod (21) is hinged, the other end of second connecting rod (21) and the pitman shaft being fixed on pedestal (1) Hingedly, third connecting rod (23) rectangular zigzag ruler shape, the other end of third connecting rod (23) is fixedly connected with oscillating rod to support frame (19) (28) lower end of upper end, oscillating rod (28) is equipped with sample (29), and oscillating rod (28) is inserted into sample slot (27);Sample slot (27), Reservoir (37) in speed-regulating type peristaltic pump (34), thermostat (35) is connected to by liquid-transport pipe-line (26), forms circulatory flow;
It is equipped on (37) on sample slot (27) equipped with the first thermometer (30) and pH meter (31), flow rate meter (32), reservoir Second temperature meter (36);
First thermometer (30) connects meter with the data output end of pH meter (31), flow rate meter (32), second temperature meter (36) Calculation machine (3);Control signal input connection computer (3) of motor (5), speed-regulating type peristaltic pump (34), thermostat (35);
Electrochemical workstation (25) passes through electrochemical workstation p-wire (42) and sample slot (27) internal electrode (41) and examination Sample (29) connection, electrochemical workstation (25) are connect by electrochemical workstation data line (43) with computer (3) bi-directional data.
CN201822259745.6U 2018-12-30 2018-12-30 Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies Expired - Fee Related CN209559726U (en)

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Application Number Priority Date Filing Date Title
CN201822259745.6U CN209559726U (en) 2018-12-30 2018-12-30 Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies

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Application Number Priority Date Filing Date Title
CN201822259745.6U CN209559726U (en) 2018-12-30 2018-12-30 Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109557021A (en) * 2018-12-30 2019-04-02 浙江工业大学 Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109557021A (en) * 2018-12-30 2019-04-02 浙江工业大学 Double acting state degradation property analytical equipment outside a kind of medical magnesium alloy implantation material bodies
CN109557021B (en) * 2018-12-30 2024-06-11 浙江工业大学 External double dynamic degradation performance analysis device for medical magnesium alloy implant material

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