CN209435971U - Small animal pathogen air borne experimental provision in high-grade biological safety protection formula - Google Patents
Small animal pathogen air borne experimental provision in high-grade biological safety protection formula Download PDFInfo
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- CN209435971U CN209435971U CN201821639687.3U CN201821639687U CN209435971U CN 209435971 U CN209435971 U CN 209435971U CN 201821639687 U CN201821639687 U CN 201821639687U CN 209435971 U CN209435971 U CN 209435971U
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Abstract
The utility model discloses small animal pathogen air borne experimental provisions in a kind of high-grade biological safety protection formula, it can be used for middle toy, such as rat, mouse, ermine, rabbit carry out droplet transmission experiment, including Biohazard Safety Equipment, Biohazard Safety Equipment includes the exposure chamber for accommodating healthy animal and animal carrier, Packed experimental box is set in exposure chamber, healthy animal and animal carrier are placed in experimental box；Biohazard Safety Equipment is equipped with supply gas filter device and exhaust and filtration apparatus, and filter device of supplying gas is blown into exposure chamber, and exhaust and filtration apparatus will be discharged after the exposure indoor gas purification of chamber；Experimental box includes air inlet and air outlet, and air inlet is connected to filter device of supplying gas, and gas outlet is connected to exhaust and filtration apparatus.The technical essential, experimental animal are placed in experimental box, and propagation experimentation does not carry out directly in Biohazard Safety Equipment, reduce pollutant range of scatter, experiment safety；The experimental box section of droplet transmission is small, is easy to get accurate experimental result.
Description
Technical field
The utility model relates to carry out the experimental provision of droplet transmission infection to animal, more particularly to a kind of high-grade life
Small animal pathogen air borne experimental provision in object safety protection type.
Background technique
Currently, in order to fast and accurately be diagnosed to infectious diseases, it is often necessary to be carried out to pathogenic microorganism comprehensive
Inspection and analysis.And inhalation toxicology is to study inhalable object body toxicological effect occurs, develop and eliminates various
Condition, rule and mechanism and a science that hazard assessment is carried out to inhalable object.Its professional research contents mainly has: air
In various substances physicochemical property；The fundamental biological knowledge of respiratory tract；Inhalation (inhalatio) deposition in vivo and delay and its with internal weight
Want the interaction between system, organ and these effects are how disease to be caused to generate.As international inhalation toxicology is ground
Study carefully and become more and more active, lot of domestic experts also fully recognizes the importance of inhalation toxicology.For example, in existing some suctions
Enter in toxicologic study, healthy animal and disease carrying germ animal are tested together, passes through the exhalation droplet etc. of disease carrying germ animal
To infect healthy animal, and then the droplet transmission infection experiment between progress animal.
And in routine experiment thinking, often animal carrier and healthy animal are placed on simultaneously identical Biohazard Safety Equipment or
Person is individually placed to carry out droplet transmission experiment in different Biohazard Safety Equipments, and Biohazard Safety Equipment exposure cavity space is bigger,
Pollutant range of scatter is increased, experiment accuracy is reduced.
Utility model content
In view of the deficienciess of the prior art, the purpose of this utility model is to provide one kind can be used for middle toy,
Such as rat, mouse, ermine, rabbit carry out small animal pathogen air in the high-grade biological safety protection formula of droplet transmission experiment and pass
Broadcast experimental provision.
To achieve the above object, the utility model provides following technical solution: a kind of high-grade biological safety protection formula
Medium and small animal pathogen air borne experimental provision, including experiment Biohazard Safety Equipment, the Biohazard Safety Equipment include for holding
Receive the exposure chamber of healthy animal and animal carrier, the Packed experimental box of setting, the healthy animal in the exposed chamber
It is placed in the experimental box with the animal carrier；
Supply gas filter device and exhaust and filtration apparatus, the filter device configuration of supplying gas are provided on the Biohazard Safety Equipment
It blows at into the exposed chamber, the exhaust and filtration apparatus is configured to the exposed indoor gas purification heel row of chamber
Out；
The experimental box includes air inlet and air outlet, and the air inlet and the filter device of supplying gas pass through gas piping
It is connected, the gas outlet is connected with the exhaust and filtration apparatus by gas piping.
Further, the Biohazard Safety Equipment includes the first Biohazard Safety Equipment and the second Biohazard Safety Equipment, and described first is raw
Object safety cabinet and second Biohazard Safety Equipment have respectively included the first exposure chamber and the second exposure chamber；
The experimental box includes the first experimental box and the second experimental box, and first experimental box is placed on first exposure
In chamber, second experimental box is placed in the second exposure chamber；
Accommodate animal carrier in first experimental box, the second experimental box content only receives unsoundness animal；
First Biohazard Safety Equipment and second Biohazard Safety Equipment, which are provided with, exposes chamber with described first respectively
The connector being connected with the second exposure chamber, the first exposure chamber and the second exposure chamber pass through the company
Interface is connected；
The filter device of supplying gas is configured to blow into the first exposure chamber, and the exhaust and filtration apparatus is configured to
It will be discharged after the second exposure indoor gas purification of chamber；
The air inlet of first experimental box is connected with the filter device of supplying gas, the gas outlet of second experimental box
It is connected with the exhaust and filtration apparatus；
The gas outlet of first experimental box is connected with the air inlet of second experimental box by gas piping.
Further, equal in the first exposure indoor experimental box of chamber and in the second exposure indoor experimental box of chamber
It is provided with animal cage, the experimental animal is placed in the animal cage.
Further, the animal cage includes that infected group animal cage, droplet transmission group animal cage and aerosol pass
Broadcast a group animal cage；
Infected group animal cage and droplet transmission group animal cage are placed in first experimental box simultaneously, described second is real
Aerosol transmission group animal cage is only placed in tryoff；
Animal carrier and healthy animal are accommodated in the infected group animal cage simultaneously；
Hold in the droplet transmission group animal cage and in the aerosol transmission group animal cage and only receives healthy animal.
Further, the inner space of first experimental box is greater than the infected group animal cage and the droplet transmission
Group animal cage total volume, second experimental box inner space are greater than volume shared by the aerosol transmission group animal cage；
The infected group animal cage and the droplet transmission group animal cage are configured to can be in first experimental box
Shift position changes the distance between the infected group animal cage and the droplet transmission group animal cage and the sense
The distance between dye group animal cage and the aerosol transmission group animal cage；
The aerosol transmission group animal cage be configured to can in second experimental box shift position, change the sense
The distance between dye group animal cage and the aerosol transmission group animal cage.
Further, the experimental box includes open plate, and the open plate is configured to open or close the experimental box；
First Biohazard Safety Equipment and second Biohazard Safety Equipment are respectively arranged with the first transferring cabin and the second transmitting
Cabin, first transferring cabin and the first exposure chamber, second transferring cabin and the second exposure chamber,
First transferring cabin and second transferring cabin are each configured to transmission experimental animal；
It is provided with IVC biosafety cage in first transferring cabin and second transferring cabin, experimental animal is placed on institute
It states and is transmitted in IVC biosafety cage.
Further, first experimental box and second experimental box are provided with upper layer and lower layer experimental box, it is described on
Experimental animal, which is accommodated, in lower two layers of experimental box carries out propagation infection experiment.
Further, the open plate bottom and the experimental box bottom edge are hinged, and the open plate can be by vertical position
It has set and has turned to horizontal limeit position around the experimental box bottom edge.
Further, first transferring cabin is connected to the filter device of supplying gas, and first transferring cabin is connected with
First air exhausting device；
Second transferring cabin is connected to the exhaust and filtration apparatus, and second transferring cabin is connected with the second air-supply dress
It sets.
Further, the Biohazard Safety Equipment is equipped with operation door, and the operation door is configured to sudden and violent described in open or close
Reveal chamber；
Interconnecting piece is installed on the operation door, the rotation with interconnecting piece cooperation is installed on the Biohazard Safety Equipment
Seat, the interconnecting piece and the rotating seat are hinged.
In the present invention, small animal pathogen air borne experiment dress in the high-grade biological safety protection formula
Set and have substantive features and progress, be mainly manifested in: 1) experimental animal is placed in experimental box, and propagation experimentation is not directly in life
It is carried out in object safety cabinet, reduces pollutant range of scatter, tested safer；2) experimental animal is divided into infected group, directly contact
Animal, droplet transmission group and aerosol transmission group, can to the experimental animal under same experimental conditions it is direct contact infection,
The droplet transmission of short distance is infected and aerosol droplet transmission infection etc. carries out observation analysis at a distance, to obtain more
Experimental data, convenient for research；3) infected group animal cage, droplet transmission group animal cage and aerosol infected group animal cage
Equal moveable position adjusts the position between infected group animal cage and aerosol infected group animal cage and infected group animal
The distance between cage tool and droplet transmission group animal cage, to carry out under different distance between animal carrier and healthy animal
Droplet transmission infection experiment observes the gradient of infection of different distance；4) experimental animal is transmitted in IVC biosafety cage by the
One transferring cabin and the second transferring cabin are transmitted, and improve experiment accuracy, safer；5) open plate of experimental box is hingedly set
It sets, in the animal transmit process in high-rise experimental box, IVC biosafety cage can be placed on the open plate on horizontal limeit position
On, it is easy to operate；6) each transferring cabin has clean gas flow flow path, for the purification of transferring cabin and transmitting article, improves experiment
Safety；7) setting operation door, and operation door is openable or is closed, and facilitates the preparation of experiment front and back.
Detailed description of the invention
Hereinafter with reference to the accompanying drawings and some specific of the utility model is described in detail in embodiment mode and not restrictive
Embodiment.Identical appended drawing reference denotes same or similar part or part in attached drawing.Those skilled in the art should manage
Solution, these attached drawings are not necessarily to scale drafting.
Fig. 1 is the knot of small animal pathogen air borne experimental provision in the high-grade biological safety protection formula of the utility model
Structure schematic diagram one；
Fig. 2 is the knot of small animal pathogen air borne experimental provision in the high-grade biological safety protection formula of the utility model
Structure schematic diagram two.
Wherein, 1. first Biohazard Safety Equipment；2. the second Biohazard Safety Equipment；3. the first exposure chamber；4. the second exposure chamber；
51. the first experimental box；52. the second experimental box；53. open plate；54. air inlet；55. gas outlet；6. infected group animal cage；7.
Droplet transmission group animal cage；8. aerosol transmission group animal cage；9. the first transferring cabin；10. the second transferring cabin；11.IVC is raw
Object nacelle 102；12. filter device of supplying gas；13. exhaust and filtration apparatus；14. connector；15. operating door.
Specific embodiment
To keep the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, below with reference to Fig. 1 to Fig. 2
The embodiment of small animal pathogen air borne experimental provision in the high-grade biological safety protection formula of the utility model is done into one
Walk explanation.
Small animal pathogen air borne experimental provision in a kind of high-grade biological safety protection formula, including bio-safety
Cabinet, Biohazard Safety Equipment include exposed chamber again, are placed with animal carrier and healthy animal in exposure chamber, pass through healthy animal
The gas for sucking animal carrier exhalation carries out droplet transmission experiment.The embodiments of the present invention are as follows: the high-grade biology peace
Small animal pathogen air borne experimental provision includes the first Biohazard Safety Equipment 1 and the second Biohazard Safety Equipment 2 in full protection formula, the
One Biohazard Safety Equipment 1 includes the first exposure chamber 3, and the second Biohazard Safety Equipment 2 includes the second exposure chamber 4.First biology
It is both provided with connector 14 on safety cabinet 1 and the second Biohazard Safety Equipment 2, flange, the first biology are connected at connector 14
The connector 14 of the connector 14 of safety cabinet 1 and the second Biohazard Safety Equipment 2 passes through flange to be bolted, so that the first exposure chamber
Room 3 is connected with the second exposure chamber 4.
It is provided with experimental box in first exposure chamber 3 and the second exposure chamber 4, experimental box is tested for accommodating with dynamic
Object.Experimental box includes the first experimental box 51 and the second experimental box 52, and the first experimental box 51 is placed in the first exposure chamber 3, and second
Experimental box 52 is placed in the second exposure chamber 4, wherein the first experimental box 51 accommodates animal carrier, and the second experimental box 52
Accommodate healthy animal.Air inlet 54 and gas outlet 55, the first experiment are offered on first experimental box 51 and the second experimental box 52
The gas outlet 55 of case 51 is connected by gas piping with the air inlet 54 of the second experimental box 52, so that in the first experimental box 51
The gas of animal carrier exhalation, which can enter into the second experimental box 52 to suck for healthy animal, carries out droplet transmission infection experiment.The
One experimental box 51 and the second experimental box 52 are all made of sealed set, and include open plate 53, the openable experiment of open plate 53
Case or closure experimental box, convenient for transmitting experimental animal or experimental apparatus etc. into experimental box.
First exposure chamber 3 is communicated with filter device 12 of supplying gas, and the second exposure chamber 4 is communicated with exhaust and filtration apparatus 13,
Exhaust and filtration apparatus 13 is connected to air pump, specific embodiment are as follows: two kinds of sides of air-supply or exhausting can be used in filter device 3 of supplying gas
Formula can be used breeze fan and filter and be sent into filtered gas into the first exposure chamber 3, and can directly adopt and arrange
The air pump that gas filter device 13 connects carries out exhausting, so that the gas in the first exposure chamber 3 passes into the second exposure chamber 4
It is interior.In addition, the air inlet 54 of the first experimental box 51 is connected to by gas piping with filter device 12 of supplying gas, the second experimental box 52
Gas outlet 55 is connected by gas piping with exhaust and filtration apparatus 13, and the gas that filter device 12 of supplying gas is sent out enters first
It is sucked in experimental box 51 for animal carrier, then the gas of animal carrier exhalation enters in the second experimental box 52 for healthy animal
Sucking.It is provided in the second experimental box 52 filter (not represented in figure), the healthy animal exhalation in the second experimental box 52
Exhaust gas filtered via filter, then extracted out by air pump.For the exhaust gas in the second exposure chamber 4, filled via exhaust gas filter
13 filterings are set to be then discharged out.Wherein, exhaust and filtration apparatus 13 includes successively interconnected level-one exhaust and filtration apparatus and second level
Exhaust and filtration apparatus, by carrying out double filtration to the exhaust gas of exhalation, so that the exhaust gas of discharge is cleaner, to reduce experiment wind
Experiment safety is improved in danger.
The utility model is further arranged to, and is placed with animal cage in the first experimental box 51 and the second experimental box 52,
Experimental animal carries out propagation infection experiment in animal cage.Infected group animal cage 6 is placed simultaneously in first experimental box 51
With droplet transmission group animal cage 7, individually placed aerosol transmission group animal cage 8 in the second experimental box 52.Wherein, infected group
Animal cage 6 is interior while placing healthy animal and animal carrier, individually placed healthy animal in droplet transmission group animal cage 7,
Individually placed healthy animal in aerosol transmission group animal cage 8.In infected group animal cage 6, healthy animal and animal carrier
It directly contacts, the gas of animal carrier exhalation can also be directly to healthy animal, so as to straight between toy in observing
The infection experiment of contact；The animal carrier in healthy animal and infected group animal cage 6 in droplet transmission group animal cage 7
Between have certain distance, can observe animal carrier exhalation gas diffusion to healthy animal at carry out incoming call droplet transmission
Infection experiment, the utility model are preferably that the distance between droplet transmission group animal cage 7 and infected group animal cage 6 are 5cm；
Aerosol transmission group animal cage 8 and infected group animal cage 6 are respectively in different exposure chambers, so that aerosol transmission group
Animal carrier of the healthy animal in infected group animal cage 6 in animal cage 8 is apart from farther, the gas of animal carrier exhalation
Cognition forms particulate aerosol and is diffused into aerosol transmission group animal cage 8 for healthy animal incoming call, to carry out long distance
From propagation infection experiment, the utility model is preferably between aerosol transmission group animal cage 8 and infected group animal cage 6
Distance is 1m-1.5m.Three kinds of different experiment samples are accommodated using three kinds of different experimental cages, reality can be obtained by experiment
Animal is tested in the different gradient of infection of different distance and apart from the minimum safe distance etc. of animal carrier.
And in the case where having different distance between animal carrier to measure, the gradient of infection of healthy animal, first
The inner space of experimental box 51 is greater than the total volume of infected group animal cage 6 and droplet transmission group animal cage 7, the second experimental box
52 inner spaces are greater than volume shared by aerosol transmission group animal cage 8, so that infected group animal cage 6 and droplet transmission group
Animal cage 7 can in the first experimental box 51 shift position, to change infected group animal cage 6 and droplet transmission group animal
The distance between the distance between cage tool 7 and infected group animal cage 6 and aerosol transmission group animal cage 8；Aerosol passes
Broadcast group animal cage 8 can in second experimental box 52 shift position, and then change infected group animal cage 6 and aerosol and pass
Broadcast the distance between group animal cage 8.
The further embodiment of the utility model is that the first transferring cabin 9 is provided on the first Biohazard Safety Equipment 1, the
Second transferring cabin 10 on two Biohazard Safety Equipments 2, the first transferring cabin 9 and the second transferring cabin 10 include cabin, transferring cabin entrance and
Transferring cabin outlet, the first transferring cabin 9 are connected in transferring cabin exit with the first exposure chamber 3, and the second transferring cabin 10 is in transferring cabin
Exit is connected to the second exposure chamber 4.First transferring cabin 9 and the first Biohazard Safety Equipment 1, the second transferring cabin 10 and the second biology
Safety cabinet 2 integrally molded can be arranged, and can also be connected by flange bolt.First transferring cabin 9 and the second transferring cabin 10 are set
It sets, is tested for extraneous experiment appliance or experimental animal to be transmitted in the first experimental box 51 or the second experimental box 52.Especially
It will avoid the gas diffusion of healthy animal sucking impurity toxic gas or animal carrier exhalation in experimental animal transmit process
It is polluted to the external world, the utility model is preferably the transmission for using IVC biosafety cage 11 to carry out experimental animal.
Preferred embodiments of the present invention are that the first experimental box 51 and the second experimental box 52 are disposed as upper and lower two
Layer, can carry out the propagation infection experiment of the experimental animal of multi-quantity.
When needing for experimental animal to be sent in experimental box, the first transferring cabin 9 or the second transferring cabin 10 are first opened, it will be real
It tests animal to be put into IVC biosafety cage 11, IVC biosafety cage 11 is sent at experimental box, open the opening of experimental box
Plate 53, taking-up experimental animal is put into experimental box then closure open plate 53, and experimental box is closed.For the experimental animal on upper layer
Pick-and-place, due to height height, need by IVC biosafety cage 11 lift to certain altitude carry out experimental animal pick-and-place, in order to make
It obtains experimental animal to be sent in experimental box out of IVC biosafety cage 11 easily and fast, open plate 53 is set as and experimental box
Bottom edge it is hinged, when needing to transmit in experimental animal to experimental box, openable open plate 53 to horizontal position, at this point,
Upward and in extreme position, IVC biosafety cage 11 can be placed in open plate 53 53 plane of open plate by experimenter
The transmission of experimental animal is carried out, structure is simple and easy to operate.
In the entire experiment process, it in order to guarantee being isolated for experiment appliance and IVC biosafety cage 11 and external environment, keeps away
Exempt from introduced contaminants or bacterium is brought into influence experiment in the first exposure chamber 3 or the second exposure chamber 4, therefore, the first transmitting
Cabin 9 is communicated with the first air exhausting device, and the second transferring cabin 10 is communicated with the second air supply device, the first transferring cabin 9 and the second transferring cabin
10 are provided with sealing door component in transferring cabin outlet and transferring cabin inlet.It is first that experiment appliance or IVC is raw in experimentation
Object nacelle 102 11 is put into the cabin of the first transferring cabin 9 or the second transferring cabin 10, is closed sealing door component, is opened the first air draft
Device or the second air supply device, at this point, supplying gas filter device 12 into the cabin of the first transferring cabin 9 in the first transferring cabin 9
Clean gas is blowed, experiment appliance or IVC biosafety cage 11 are rinsed, while the first air exhausting device is transmitted first
The indoor exhaust gas extraction in the cabin in cabin 9, completes the cleaning to experiment appliance or IVC biosafety cage 11 in the first transferring cabin 9；For
Experiment appliance or IVC biosafety cage 11 in second transferring cabin 10, the second air supply device is into the cabin of the second transferring cabin 10
Pure air is blowed to be rinsed experiment appliance or IVC biosafety cage 11, it is flushed after exhaust gas successively arranged via level-one
Gas filter device and secondary exhaust filter device are discharged, so complete to the indoor experiment appliance in cabin of the second transferring cabin 10 or
The cleaning of IVC biosafety cage 11.
The further embodiment of the utility model is that the first Biohazard Safety Equipment 1 and the second Biohazard Safety Equipment 2 include side
Wall and opening face, be open face at be fitted with operation door 15, on the top of the first Biohazard Safety Equipment 1 and the second Biohazard Safety Equipment 2
Portion edge on be fixedly installed at least three rotating seats, the length of rotating seat the first Biohazard Safety Equipment 1 and the second Biohazard Safety Equipment 2
Degree direction arranges, and rotating seat includes pedestal and the rotating part hinged with pedestal, and rotating part can be rotated around its articulated shaft；Operate door
15 top sides along it is upper it is integrally molded be connected with interconnecting piece, interconnecting piece is fixedly connected with rotating part, i.e., interconnecting piece and rotating seat are cut with scissors
It connects in succession, so that operation door 15 can be rotated around the articulated shaft of interconnecting piece and rotating seat.The integrally molded or spiral shell on operation door 15
The pneumatic bomb spring abutment (not representing in figure) being fixedly connected is followed closely, pneumatic bomb spring abutment is hingedly connected with pneumatic spring, and pneumatic bomb
The other end of spring and the first Biohazard Safety Equipment 1 or the second Biohazard Safety Equipment 2 are hinged, when needing to open operation door 15, pneumatic bomb
Spring work drives operation door 15 to open to suitable position, controls pneumatic spring stop motion at this time, and pneumatic spring automatically latches to
The position.Openable or closure operation door 15 is set, the preparation of experiment front and back is facilitated.
The above is only the preferred embodiment of the utility model, it is noted that for the common skill of the art
For art personnel, without departing from the principle of this utility model, made any improvements and modifications also should be regarded as this reality
With novel protection scope.
Claims (10)
1. small animal pathogen air borne experimental provision in a kind of high-grade biological safety protection formula, including experiment biology peace
Full cabinet, the Biohazard Safety Equipment includes the exposure chamber for accommodating healthy animal and animal carrier, it is characterized in that: the exposure
The Packed experimental box of setting in chamber, the healthy animal and the animal carrier are placed in the experimental box；
Be provided with supply gas filter device and exhaust and filtration apparatus on the Biohazard Safety Equipment, the filter device of supplying gas be configured to
Air-supply, the exhaust and filtration apparatus are configured to be discharged after the exposed indoor gas purification of chamber in the exposed chamber；
The experimental box includes air inlet and air outlet, and the air inlet is connected with the filter device of supplying gas by gas piping
Logical, the gas outlet is connected with the exhaust and filtration apparatus by gas piping.
2. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 1,
It is characterized in that: the Biohazard Safety Equipment includes the first Biohazard Safety Equipment and the second Biohazard Safety Equipment, first Biohazard Safety Equipment
The first exposure chamber and the second exposure chamber have been respectively included with second Biohazard Safety Equipment；
The experimental box includes the first experimental box and the second experimental box, and first experimental box is placed on the first exposure chamber
Interior, second experimental box is placed in the second exposure chamber；
Animal carrier is accommodated in first experimental box, only accommodates healthy animal in second experimental box；
First Biohazard Safety Equipment and second Biohazard Safety Equipment, which are provided with, exposes chamber and institute with described first respectively
The connector that the second exposure chamber is connected is stated, the first exposure chamber and the second exposure chamber pass through the connector
It is connected；
The filter device of supplying gas is configured to blow into the first exposure chamber, and the exhaust and filtration apparatus is configured to institute
It is discharged after stating the second exposure indoor gas purification of chamber；
The air inlet of first experimental box is connected with the filter device of supplying gas, the gas outlet of second experimental box and institute
Exhaust and filtration apparatus is stated to be connected；
The gas outlet of first experimental box is connected with the air inlet of second experimental box by gas piping.
3. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 2,
It is characterized in that being provided with animal cage, the animal carrier and institute in first experimental box and in second experimental box
Healthy animal is stated to be placed in the animal cage.
4. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 3,
It is characterized in that: the animal cage includes infected group animal cage, droplet transmission group animal cage and aerosol transmission group animal
Cage tool；
Infected group animal cage and droplet transmission group animal cage, second experimental box are placed in first experimental box simultaneously
Interior placement aerosol transmission group animal cage；
Animal carrier and healthy animal are accommodated in the infected group animal cage simultaneously；
Healthy animal is only accommodated in the droplet transmission group animal cage and in the aerosol transmission group animal cage.
5. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 4,
It is characterized in that: the inner space of first experimental box is greater than the infected group animal cage and the droplet transmission group cage for animal
Has total volume, second experimental box inner space is greater than volume shared by the aerosol transmission group animal cage；
The infected group animal cage and the droplet transmission group animal cage are configured to move in first experimental box
Position changes the distance between the infected group animal cage and the droplet transmission group animal cage and the infected group
The distance between animal cage and the aerosol transmission group animal cage；
The aerosol transmission group animal cage be configured to can in second experimental box shift position, change the infected group
The distance between animal cage and the aerosol transmission group animal cage.
6. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 2,
It is characterized in that: the experimental box includes open plate, the open plate is configured to open or close the experimental box；
First Biohazard Safety Equipment and second Biohazard Safety Equipment are respectively arranged with the first transferring cabin and the second transferring cabin, institute
The first transferring cabin and the first exposure chamber, second transferring cabin and the second exposure chamber are stated, it is described
First transferring cabin and second transferring cabin are each configured to transmission experimental animal；
IVC biosafety cage is provided in first transferring cabin and second transferring cabin, experimental animal is placed on described
It is transmitted in IVC biosafety cage.
7. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 6,
It is characterized in that: first experimental box and second experimental box are provided with upper layer and lower layer experimental box, bilevel experiment
Animal carrier is accommodated in case and healthy animal carries out propagation infection experiment.
8. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 7,
It is characterized in that: the open plate bottom and the experimental box bottom edge are hinged, the open plate can be by vertical position around institute
It states experimental box bottom edge and turns to horizontal limeit position.
9. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 6,
It is characterized in that: first transferring cabin is connected to the filter device of supplying gas, and first transferring cabin is connected with the first air draft
Device；
Second transferring cabin is connected to by pipeline with the exhaust and filtration apparatus, and second transferring cabin is connected with second and send
Wind apparatus.
10. small animal pathogen air borne experimental provision in high-grade biological safety protection formula according to claim 1,
It is characterized in that: the Biohazard Safety Equipment is equipped with operation door, the operation door is configured to exposure chamber described in open or close；
Interconnecting piece is installed on the operation door, the rotating seat with interconnecting piece cooperation is installed on the Biohazard Safety Equipment,
The interconnecting piece and the rotating seat are hinged.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821639687.3U CN209435971U (en) | 2018-10-10 | 2018-10-10 | Small animal pathogen air borne experimental provision in high-grade biological safety protection formula |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821639687.3U CN209435971U (en) | 2018-10-10 | 2018-10-10 | Small animal pathogen air borne experimental provision in high-grade biological safety protection formula |
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| CN209435971U true CN209435971U (en) | 2019-09-27 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111011221A (en) * | 2018-10-10 | 2020-04-17 | 中国人民解放军军事科学院军事医学研究院 | High-grade biological safety protection type small and medium animal pathogen air transmission experimental device |
-
2018
- 2018-10-10 CN CN201821639687.3U patent/CN209435971U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111011221A (en) * | 2018-10-10 | 2020-04-17 | 中国人民解放军军事科学院军事医学研究院 | High-grade biological safety protection type small and medium animal pathogen air transmission experimental device |
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