CN204841720U - Biohazard safety equipment is with small -size aerosol transmission evaluation test device - Google Patents

Biohazard safety equipment is with small -size aerosol transmission evaluation test device Download PDF

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Publication number
CN204841720U
CN204841720U CN201420494066.6U CN201420494066U CN204841720U CN 204841720 U CN204841720 U CN 204841720U CN 201420494066 U CN201420494066 U CN 201420494066U CN 204841720 U CN204841720 U CN 204841720U
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CN
China
Prior art keywords
chamber
aerosol
cabin
infection
exposure compartment
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201420494066.6U
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Chinese (zh)
Inventor
钱军
刘林娜
赵思言
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Institute of Military Veterinary Academy of Military Medical Sciences PLA
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Institute of Military Veterinary Academy of Military Medical Sciences PLA
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Application filed by Institute of Military Veterinary Academy of Military Medical Sciences PLA filed Critical Institute of Military Veterinary Academy of Military Medical Sciences PLA
Priority to CN201420494066.6U priority Critical patent/CN204841720U/en
Application granted granted Critical
Publication of CN204841720U publication Critical patent/CN204841720U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a biohazard safety equipment is with small -size aerosol transmission evaluation test device, expose cabin, flexible coupling, interlocking transfer gate, safety cabinet supply -air outlet, fan, safety cabinet including the fast interface of aerosol generator, ball valve, aerosol, the aerosol exposes the cabin and is connected with the aerosol generator through fast interface of aerosol generator and ball valve, the safety cabinet includes separation net, high efficiency filter, catch tray, the safety cabinet bottom is the spacer screen, the separation net is installed and is separated into the safety cabinet infection chamber, is propagated the chamber above the safety cabinet spacer screen, flexible coupling one end is connected the aerosol through the interlocking transfer gate and is exposed the cabin, and the infection chamber of safety cabinet is connected to the other end through the interlocking transfer gate, the fan is installed and is being infected the chamber outer wall, and fan and infection chamber are linked together, high efficiency filter is linked together with the air exit of propagating the chamber rear end, the air current is from infecting the chamber to propagating the one -way directional flow in chamber, device negative pressure, the below at the spacer screen is installed to the catch tray, through buckle sealing connection between catch tray and the safety cabinet box.

Description

A kind of Biohazard Safety Equipment Compact Aerosol propagates evaluation experimental device
Technical field
The utility model belongs to medical science or veterinary science scientific research technique with the apparatus field, relate to a kind of Biohazard Safety Equipment Compact Aerosol and propagate evaluation experimental device, be specially adapted to contact transmission or aerosol transmission experimental study between animal, be particularly useful for the minitype animal experiments such as mouse, rat, cavy, for the experimental study that new bacterial isolate, pathogenic pathogenic and transmission capacity that is not clear or that enter P3 laboratory rank cause of disease not just judge.
Background technology
Existing aerosol transmission evaluating apparatus volume is awkward more greatly, and there is bio-safety risk.
Some new bacterial isolate or pathogenic not clear cause of disease, directly cannot enter P3 laboratory and carry out related experiment, for its pathogenicity of desk study and transmission capacity, judge whether to need to enter P3 laboratory, grasp its biological property, evade bio-safety risk, need a kind of facility to carry out first step experiment in II level Biohazard Safety Equipment, so that safety obtains test data rapidly again.
Summary of the invention
The utility model discloses a kind of Biohazard Safety Equipment Compact Aerosol and propagate evaluation experimental device, be awkward more greatly to solve aerosol transmission evaluating apparatus volume in prior art, and there is bio-safety risk; Some new bacterial isolate or pathogenic not clear cause of disease, need a kind of facility to carry out first step experiment in II level Biohazard Safety Equipment, so that safety obtains the problems such as test data rapidly again.
The utility model comprises the fast interface of aerosol generator, ball valve, aerosol exposure compartment, is flexible coupling, interlocks transfer gate, propagates and evaluate cabin air outlet, blower fan, food dish, propagation evaluation cabin; Aerosol exposure compartment air inlet is connected with aerosol generator with ball valve by the fast interface of aerosol generator; Propagate evaluation cabin and comprise separation net, high efficiency particulate air filter, catch tray; Propagating and evaluating bilge portion is cancellated spacer screen; Separation net is arranged on to propagate to be evaluated in the online square casing of the bilge; Separation net is separated into anterior infection chamber, the propagation chamber at rear portion by propagating the casing evaluating the online side of the bilge; Be flexible coupling one end and aerosol exposure compartment connector is tightly connected, be flexible coupling the other end with propagate the infection chamber connector evaluating front portion, cabin and be tightly connected; Be flexible coupling and be communicated with aerosol exposure compartment and infect chamber; Interlocking transfer gate is arranged on and is flexible coupling with the aerosol exposure compartment connector place of being tightly connected and is flexible coupling to be tightly connected with infection chamber connector and locate, realizes sealing and self-cleaning; Assembling is on infection cavity outer wall, and fans entrance is evaluated cabin air outlet with propagation and is connected, and fan outlet is connected with infection chamber; High efficiency particulate air filter entrance is connected with the exhaust outlet propagating cavity rear end; High efficiency particulate air filter outlet is connected with exhaust outlet; Air-flow flows from infection chamber to propagation chamber unidirectional orientation, device negative pressure state; Catch tray is arranged on the below of spacer screen; Catch tray and propagation are evaluated between the casing of cabin and are tightly connected by buckle.Aerosol enters exposure compartment air inlet by the fast interface of generator and valve, in exposure compartment, carry out aerosol infection to animal; By exposure compartment and infect interlocking transfer gate between chamber with being flexible coupling infection animal to be passed to and infects chamber, and place the animal used as test do not infected propagating in chamber; Intermediate isolating net, achieves the control to animal used as test, avoids contact stain; Open blower fan, control air-flow from infection chamber to the unidirectional orientation flowing of propagation chamber, device negative pressure state, and vacuum magnitude is adjustable, air-flow is discharged in high efficiency particulate air filter purification, ensures bio-safety.The collection of animal excrements in experimentation is carried out by the catch tray of below.
The utility model infects chamber and the separation net propagated between chamber is twice, and eliminating animal contact may.
The utility model also comprises exposure compartment roughing efficiency air filter, exposure compartment high efficiency particulate air filter, exhaust outlet; Exposure compartment roughing efficiency air filter, be arranged on aerosol exposure compartment top; Exposure compartment high efficiency particulate air filter is arranged between aerosol exposure compartment upper exposed cabin roughing efficiency air filter and exhaust outlet; Exhaust outlet is connected with air outlet, and after animal exposes, gas is drained in Biohazard Safety Equipment by exhaust outlet discharge through exposure compartment roughing efficiency air filter, exposure compartment high efficiency particulate air filter after purification, then is discharged by the purification of Biohazard Safety Equipment high efficiency particulate air filter.
The utility model also comprises exposure hatch door, infects chamber door; Food dish is placed in and infects in chamber, propagation chamber; Expose hatch door, infect chamber door and be respectively lower frame and aerosol exposure compartment, propagate and evaluate cabin and seal and be articulated and connected, expose hatch door, infect chamber door periphery and aerosol exposure compartment, propagate to evaluate between cabin sealing joint strip is installed, exposure hatch door, the aerosol exposure compartment infecting door upper side frame place, chamber, propagation are evaluated on cabin and are provided with buckle, lock exposure hatch door, infect chamber door; Expose hatch door, infection chamber door is turnover from top to bottom and opens, prevent animal escape; Exposing hatch door by opening, infecting chamber door and carry out feed in animal feeding process, the pollution-free interpolation problem of drinking-water and animal sample collection.
The utility model also comprises Temperature Humidity Sensor, pressure sensor, thermohygrometer, Pressure gauge; Temperature Humidity Sensor, pressure sensor are arranged on to propagate to be evaluated in the casing of cabin; Thermohygrometer is connected with Temperature Humidity Sensor; Pressure gauge is connected with pressure sensor.
Good effect of the present utility model is: small volume, simple to operate; Air-flow is from infecting chamber to the direction flowing of propagating chamber, and in exhaust ports, high efficiency particulate air filter is set, purifying exhaust gas, animal exposes to infect from aerosol and is in cabin interior completely to propagation experimentation, and in Biohazard Safety Equipment, carry out subsequent experimental to direct after animal sampling, there is not bio-safety risk; Simple structure, convenient for installation and maintenance; Can carry out aerosol infection at Biohazard Safety Equipment and propagate evaluation experimental, function advanced person be sound; For aerosol transmission evaluation test, there is good practical value.
Accompanying drawing explanation
Fig. 1 is the utility model structural front view;
Fig. 2 is that utility model infects chamber side view;
In figure: the fast interface of 1 aerosol generator, 2 ball valves, 3 aerosol exposure compartments, 4 roughing efficiency air filters, 5 high efficiency particulate air filters, 6 exhaust outlets, 7 exposure hatch doors, 8 are flexible coupling, 9 interlocking transfer gates, 10 air outlets, 11 blower fans, 12 infect chambeies, 13 and infect chamber doors, 14 food dishes, 15 separation nets, 16 propagation chambeies, 17 high efficiency particulate air filters, 18 exhaust outlets, 19 Temperature Humidity Sensors, 20 pressure sensors, 21 thermohygrometers, 22 Pressure gauges, 23 catch traies, 24 spacer screens.
Detailed description of the invention
An embodiment of the present utility model is described in detail below in conjunction with accompanying drawing.
The utility model embodiment as shown in Figure 1 and Figure 2, comprises the fast interface 1 of aerosol generator, ball valve 2, aerosol exposure compartment 3, roughing efficiency air filter 4, high efficiency particulate air filter 5, exhaust outlet 6, exposes hatch door 7, is flexible coupling 8, interlocking transfer gate 9, air outlet 10, blower fan 11, infects chamber door 13, food dish 14, Temperature Humidity Sensor 19, pressure sensor 20, thermohygrometer 21, Pressure gauge 22, propagates and evaluate cabin; Aerosol exposure compartment 3 air inlet is connected with aerosol generator with ball valve 2 by the fast interface 1 of aerosol generator; Roughing efficiency air filter 4, be arranged on aerosol exposure compartment 3 top; High efficiency particulate air filter 5 is arranged between aerosol exposure compartment 3 top roughing efficiency air filter and exhaust outlet 6; Temperature Humidity Sensor 19, pressure sensor 20 are arranged on to propagate to be evaluated in the casing of cabin; Thermohygrometer 21 is connected with Temperature Humidity Sensor 19; Pressure gauge 22 is connected with pressure sensor 20.
As shown in Figure 1 and Figure 2, safety cabinet comprises twice separation net 15, high efficiency particulate air filter 17, catch tray 23; Propagating and evaluating bilge portion is cancellated spacer screen 24; The casing propagated above the spacer screen 24 evaluating cabin is separated into anterior infection chamber 12, the propagation chamber 16 at rear portion by twice separation net 15; Be flexible coupling 8 one end and aerosol exposure compartment 3 connector is tightly connected, be flexible coupling 8 other ends with propagate infection chamber 12 connector evaluating front portion, cabin and be tightly connected; Be flexible coupling 8 connection aerosol exposure compartments 3 and infection chamber 12.Interlocking transfer gate 9 be arranged on be flexible coupling 8 with the aerosol exposure compartment 3 connector place of being tightly connected and be flexible coupling 8 with infect chamber 12 connector and be tightly connected and locate, realize sealing and self-cleaning.Air-flow flows from infection chamber to propagation chamber unidirectional orientation, device negative pressure state.Twice separation net 15 eliminates animal contact may.
As shown in Figure 1 and Figure 2, blower fan 11 is arranged on and infects on the outer wall of chamber 12, and exhaust outlet 6 is connected with air outlet 10, and blower fan 11 entrance is connected with air outlet 10, and blower fan 11 exports and is connected with infection chamber 12; High efficiency particulate air filter 17 entrance is connected with the exhaust outlet propagating rear end, chamber 16; High efficiency particulate air filter 17 outlet is connected with exhaust outlet 18; After animal exposes, gas to be discharged by exhaust outlet 6 through roughing efficiency air filter 4, high efficiency particulate air filter 5 and is drained in Biohazard Safety Equipment after purification, then is purified by Biohazard Safety Equipment high efficiency particulate air filter 17 and discharge.
As shown in Figure 1, catch tray 23 is arranged on the below of spacer screen 24; Catch tray 23 and propagation are evaluated between the body of cabin and are tightly connected by buckle; Separation net 15 is arranged in the casing above propagation evaluation bilge net 24.
As shown in Figure 1 and Figure 2, food dish 14 is placed in and infects in chamber 12, propagation chamber 16; Expose hatch door 7, infect chamber door 13 and be respectively lower frame and aerosol exposure compartment 3, propagate and evaluate cabin and seal and be articulated and connected, expose hatch door 7, infect chamber door 13 periphery and aerosol exposure compartment 3, propagate to evaluate between cabin sealing joint strip is installed, exposure hatch door 7, the aerosol exposure compartment 3 infecting door 13 upper side frame place, chamber, propagation are evaluated on cabin and are provided with buckle, lock exposure hatch door 7, infect chamber door 13; Expose hatch door 7, infection chamber door 13 is turnover from top to bottom and opens, prevent animal escape; Exposing hatch door 7 by opening, infecting chamber door 13 and carry out feed in animal feeding process, the pollution-free interpolation problem of drinking-water and animal sample collection.
Aerosol enters exposure compartment air inlet by the fast interface of generator and valve, in exposure compartment, carry out aerosol infection to animal; By exposure compartment and infect interlocking transfer gate 9 between chamber with being flexible coupling and 8 infection animal to be passed to and to infect chamber, and place the animal used as test do not infected propagating in chamber; Intermediate isolating net, achieves the control to animal used as test, avoids contact stain; Open blower fan, control air-flow from infection chamber to the unidirectional orientation flowing of propagation chamber, device negative pressure state, and vacuum magnitude is adjustable, air-flow is discharged in high efficiency particulate air filter purification, ensures bio-safety.The collection of animal excrements in experimentation is carried out by the catch tray 23 of below.
The course of work:
1) this device is placed in Biohazard Safety Equipment;
2) animal is positioned in exposure compartment, connects aerosol generator, animal is exposed and infects;
3) open blower fan, air-flow starts one-way flow;
4) intact animal is placed in propagation chamber; Exposure compartment is connected to by being flexible coupling and infects chamber, animal after infection is passed to and infects in chamber; Disconnection is flexible coupling;
5) animal feeding certain hour, tests two treated animals respectively, record experimental result;
6) after sacrifice of animal, to carrying out spray sterilization inside and outside this device; By the bio-safety bag sealing of catch tray entirety, clear up after autoclave sterilization.

Claims (5)

1. a Biohazard Safety Equipment Compact Aerosol propagates evaluation experimental device; It is characterized in that: comprise the fast interface of aerosol generator, ball valve, aerosol exposure compartment, be flexible coupling, interlock transfer gate, propagate and evaluate cabin air outlet, blower fan, food dish, propagation evaluation cabin; Aerosol exposure compartment air inlet is connected with aerosol generator with ball valve by the fast interface of aerosol generator; Propagate evaluation cabin and comprise separation net, high efficiency particulate air filter, catch tray; Propagating and evaluating bilge portion is cancellated spacer screen; Separation net is arranged on to propagate to be evaluated in the online square casing of the bilge; Separation net is separated into anterior infection chamber, the propagation chamber at rear portion by propagating the casing evaluating the online side of the bilge; Be flexible coupling one end and aerosol exposure compartment connector is tightly connected, be flexible coupling the other end with propagate the infection chamber connector evaluating front portion, cabin and be tightly connected; Be flexible coupling and be communicated with aerosol exposure compartment and infect chamber; Interlocking transfer gate is arranged on and is flexible coupling with the aerosol exposure compartment connector place of being tightly connected and is flexible coupling to be tightly connected with infection chamber connector and locate, realizes sealing and self-cleaning; Assembling is on infection cavity outer wall, and fans entrance is evaluated cabin air outlet with propagation and is connected, and fan outlet is connected with infection chamber; High efficiency particulate air filter entrance is connected with the exhaust outlet propagating cavity rear end; High efficiency particulate air filter outlet is connected with exhaust outlet; Air-flow flows from infection chamber to propagation chamber unidirectional orientation, device negative pressure state; Catch tray is arranged on the below of spacer screen; Catch tray and propagation are evaluated between the casing of cabin and are tightly connected by buckle.
2. a kind of Biohazard Safety Equipment Compact Aerosol according to claim 1 propagates evaluation experimental device; It is characterized in that: the separation net infected between chamber and propagation chamber is twice.
3. a kind of Biohazard Safety Equipment Compact Aerosol according to claim 1 propagates evaluation experimental device; It is characterized in that: also comprise exposure compartment roughing efficiency air filter, exposure compartment high efficiency particulate air filter, exhaust outlet; Exposure compartment roughing efficiency air filter, be arranged on aerosol exposure compartment top; Exposure compartment high efficiency particulate air filter is arranged between aerosol exposure compartment upper exposed cabin roughing efficiency air filter and exhaust outlet; Exhaust outlet is connected with air outlet.
4. a kind of Biohazard Safety Equipment Compact Aerosol according to claim 1 propagates evaluation experimental device; It is characterized in that: also comprise and expose hatch door, infection chamber door; Food dish is placed in and infects in chamber, propagation chamber; Expose hatch door, infect chamber door and be respectively lower frame and aerosol exposure compartment, propagate and evaluate cabin and seal and be articulated and connected, expose hatch door, infect chamber door periphery and aerosol exposure compartment, propagate to evaluate between cabin sealing joint strip is installed, exposure hatch door, the aerosol exposure compartment infecting door upper side frame place, chamber, propagation are evaluated on cabin and are provided with buckle, lock exposure hatch door, infect chamber door.
5. a kind of Biohazard Safety Equipment Compact Aerosol according to claim 1 propagates evaluation experimental device; It is characterized in that: also comprise Temperature Humidity Sensor, pressure sensor, thermohygrometer, Pressure gauge; Temperature Humidity Sensor, pressure sensor are arranged on to propagate to be evaluated in the casing of cabin; Thermohygrometer is connected with Temperature Humidity Sensor; Pressure gauge is connected with pressure sensor.
CN201420494066.6U 2014-08-29 2014-08-29 Biohazard safety equipment is with small -size aerosol transmission evaluation test device Expired - Fee Related CN204841720U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420494066.6U CN204841720U (en) 2014-08-29 2014-08-29 Biohazard safety equipment is with small -size aerosol transmission evaluation test device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201420494066.6U CN204841720U (en) 2014-08-29 2014-08-29 Biohazard safety equipment is with small -size aerosol transmission evaluation test device

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Publication Number Publication Date
CN204841720U true CN204841720U (en) 2015-12-09

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111011228A (en) * 2018-10-10 2020-04-17 中国人民解放军军事科学院军事医学研究院 Negative pressure isolator type pathogen air transmission experimental device
CN111011221A (en) * 2018-10-10 2020-04-17 中国人民解放军军事科学院军事医学研究院 High-grade biological safety protection type small and medium animal pathogen air transmission experimental device
CN116806710A (en) * 2023-05-25 2023-09-29 军事科学院军事医学研究院军事兽医研究所 Medium and small animal aerosol exposure test equipment

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111011228A (en) * 2018-10-10 2020-04-17 中国人民解放军军事科学院军事医学研究院 Negative pressure isolator type pathogen air transmission experimental device
CN111011221A (en) * 2018-10-10 2020-04-17 中国人民解放军军事科学院军事医学研究院 High-grade biological safety protection type small and medium animal pathogen air transmission experimental device
CN116806710A (en) * 2023-05-25 2023-09-29 军事科学院军事医学研究院军事兽医研究所 Medium and small animal aerosol exposure test equipment
CN116806710B (en) * 2023-05-25 2024-02-13 军事科学院军事医学研究院军事兽医研究所 Medium and small animal aerosol exposure test equipment

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Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20151209

Termination date: 20160829

CF01 Termination of patent right due to non-payment of annual fee