CN209412194U - A kind of kit being applicable in CAR-T cell detection - Google Patents

A kind of kit being applicable in CAR-T cell detection Download PDF

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Publication number
CN209412194U
CN209412194U CN201822256238.7U CN201822256238U CN209412194U CN 209412194 U CN209412194 U CN 209412194U CN 201822256238 U CN201822256238 U CN 201822256238U CN 209412194 U CN209412194 U CN 209412194U
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China
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box body
energy
thermoelectric generation
generation film
kit
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CN201822256238.7U
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Chinese (zh)
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田晓丽
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Shanghai Yi Hao Biotechnology Co Ltd
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Shanghai Yi Hao Biotechnology Co Ltd
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Abstract

The utility model provides a kind of kit for being applicable in CAR-T cell detection, including box cover, box body, in the two, under be fitted and fixed with, reagent bottle frame is set in box body, generating and cooling component is set in the box body, including solar panels, energy-storage liquid, thermoelectric generation film, cooling piece, energy-storage battery, flow cavity and micro air pump, this kit is charged the battery using solar panels, the heat energy-storage liquid dissipated in charging process, thermoelectric generation film two sides bad student's temperature difference, then it generates electricity, energy-storage battery starts cooling piece, its output end is towards flow cavity, further increase thermoelectric generation film temperature difference, micro air pump starting simultaneously, flow cavity and box body intracavity gas are circulated, to make the intracavitary holding low temperature of box body, preferably keep medical fluid performance in reagent bottle, it is provided additionally with the advantage of environmental protection, and improve energy utilization rate.

Description

A kind of kit being applicable in CAR-T cell detection
Technical field
The utility model relates to Cell Measurement Technique field more particularly to a kind of kits for being applicable in CAR-T cell detection.
Background technique
CAR-T therapy has shown splendid therapeutic effect in clinical tumor test, is that very potential cancer is controlled New way is treated, CAR genetic comparison is crucial in therapeutic process, needs continual analysis to detect, existing detection reagent generally needs low temperature Save, but generally without temperature adjustment device in detection kit box body on the market, can only by peripheral hardware incubator or cabinet into Row saves, inconvenient for use, needs to improve.
Utility model content
In view of this, solution tries on the market the purpose of the utility model is to provide the kit for being applicable in CAR-T cell detection The problem of agent box is without register.
In order to solve the above technical problems, the technical solution of the utility model is:
A kind of kit being applicable in CAR-T cell detection, including box cover, box body, the two are fitted and fixed with above and below, in box body If reagent bottle frame, generating and cooling component, including solar panels, energy-storage liquid, thermoelectric generation film, cooling piece, storage are set in the box body Energy battery and micro air pump, box body two sides successively set solar panels, thermoelectric generation film, cooling piece from outside to inside, and wherein the temperature difference is sent out Liquid storage chamber is set between electric piece and solar panels, liquid storage chamber includes energy-storage liquid, flow cavity is set between thermoelectric generation film and cooling piece, and Cooling piece refrigeration end is towards thermoelectric generation film, and flow cavity both ends set venting cavity, and connection box body is intracavitary, sets on one venting cavity miniature Air pump, thermoelectric generation film, solar panels and energy-storage battery connect, and energy-storage battery is connect with micro air pump.
This kit is charged the battery using solar panels, the heat energy-storage liquid dissipated in charging process, temperature difference hair Electric piece two sides bad student's temperature difference, then generates electricity, and energy-storage battery starts cooling piece, and output end further increases temperature towards flow cavity Poor power generation sheet temperature difference, while micro air pump starts, and flow cavity and box body intracavity gas is circulated, to make the intracavitary guarantor of box body Low temperature is held, medical fluid performance in reagent bottle is preferably kept, is provided additionally with the advantage of environmental protection, and improves energy utilization rate.
Further, the cooling piece uses semiconductor chilling plate, reduces cost.
Further, the box body two sides are recessed installation space, and cell wall and lower cell wall constitute solar energy in further groove Plate, thermoelectric generation film, the mounting bracket of cooling piece.
Box body structure is redesigned, forms the installation space of thermoelectric generation film etc. with two sides inner groovy body, cell wall is as peace Bracket is filled, the structures such as the mounting rack of peripheral hardware are saved, reduces cost, while integral structure, improves stability.
Further, the energy-storage battery is located at box body bottom.
Further, heat detector is set in the box body, by heat detector monitor box body cavity temperature, helps and maintain temperature in box body Degree.
Further, convex under the reagent bottle frame bottom, and its middle part indent, bottom is convex in corresponding box body, is fitted into solid It is fixed, improve stability.
This kit cooperates heat detector to control the start and stop of micro air pump, cooling piece by PLC control terminal, effectively ties up It holds box body cavity temperature and is in a certain range.
The utility model has the beneficial effects that this reagent cartridge configuration is novel, effectively maintain temperature in kit, have environmental protection, The high advantage of energy utilization rate.
Detailed description of the invention
Fig. 1: the utility model structure chart in embodiment 1;
In figure: 1, box body;2, box cover;3, reagent bottle frame;4, reagent bottle;5, solar panels;6, energy-storage liquid;7, thermo-electric generation Piece;8, flow cavity;9, cooling piece;10, micro air pump;11, energy-storage battery;12, venting cavity;13, convex;14, control terminal;21, Chimeric nose;31, elastic layer;32, convex under.
Specific embodiment
Below in conjunction with attached drawing, specific embodiment of the present utility model is described in further detail, so that the utility model skill Art scheme is more readily understood and grasps.
Embodiment 1
Fig. 1 illustrates a kind of specific structure of kit for being applicable in CAR-T cell detection, including box cover 2, box body 1, the two It is fitted and fixed with above and below, box cover edge is slotted towards chimeric nose 21, corresponding box body edge placement is divided into;
Reagent bottle frame 3 is set in box body, convex 32 under reagent bottle frame bottom, and its middle part indent, in corresponding box body on bottom Convex 13, it is fitted and fixed with, has multiple slots on reagent bottle frame, reagent bottle 4 is filled in slot, more preferably, elastic layer 31 is coated in slot, it is excellent Rubber layer is selected, bradyseism improves stability, reagent bottle preferred buffer reagent bottle, APCCD3 reagent bottle, Biotin-Protein L Reagent bottle and SA-PE reagent bottle, effectively to detect CAR molecule, specific detection technique step is known content, without being described in detail;
Generating and cooling component, including solar panels 5, energy-storage liquid 6, thermoelectric generation film 7, cooling piece 9, energy storage electricity are set in box body Pond 11 and micro air pump 10, box body two sides are recessed installation space, in further groove cell wall and lower cell wall constitute solar panels, Thermoelectric generation film, the mounting bracket of cooling piece, box body two sides successively set solar panels, thermoelectric generation film, cooling piece from outside to inside, Liquid storage chamber is wherein set between thermoelectric generation film and solar panels, liquid storage chamber includes energy-storage liquid 6, selects water, thermoelectric generation film and system Flow cavity 8 is set between cold, and cooling piece refrigeration end, towards thermoelectric generation film, flow cavity both ends set venting cavity 12, are connected to box body It is intracavitary, set micro air pump 10 on one venting cavity, energy-storage battery 11 be mounted on in bottom chamber, thermoelectric generation film, solar panels It is connect with energy-storage battery, energy-storage battery is connect with micro air pump, and wherein cooling piece uses semiconductor chilling plate, thermoelectric generation film choosing With dedicated thermoelectric generation film, heat detector 9 is set in the intracavitary one side wall of box body, passes through heat detector monitor box body cavity temperature.
This kit cooperates the starting of heat detector control micro air pump, cooling piece by the PLC control terminal 14 of box body bottom With stopping, effectively box body cavity temperature is maintained to be in a certain range.
The course of work: being charged the battery using solar panels, and charge port is carried on box body, can be precharged, solar panels The heat energy-storage liquid dissipated in charging process, thermoelectric generation film two sides bad student's temperature difference, then generates electricity, energy-storage battery starting system Cold, output end further increases thermoelectric generation film temperature difference towards flow cavity, while micro air pump starts, and will flow Chamber and box body intracavity gas circulate, thus make the intracavitary holding low temperature of box body, heat detector monitoring, convenient for maintaining box body cavity temperature, Preferably keep medical fluid performance in reagent bottle.
Certainly, the above is only the specific application examples of the utility model, do not constitute and appoint to the protection scope of the utility model What is limited.Any technical scheme formed by adopting equivalent transformation or equivalent replacement, all falls within the utility model rights protection model Within enclosing.

Claims (6)

1. a kind of kit for being applicable in CAR-T cell detection, including box cover, box body, the two are fitted and fixed with above and below, set in box body Reagent bottle frame, which is characterized in that set generating and cooling component in the box body, including solar panels, energy-storage liquid, thermoelectric generation film, Cooling piece, energy-storage battery and micro air pump, box body two sides successively set solar panels, thermoelectric generation film, cooling piece from outside to inside, Liquid storage chamber is set between middle thermoelectric generation film and solar panels, liquid storage chamber includes energy-storage liquid, sets between thermoelectric generation film and cooling piece Flow cavity, and cooling piece refrigeration end, towards thermoelectric generation film, flow cavity both ends set venting cavity, and connection box body is intracavitary, one ventilation Micro air pump is set on chamber, thermoelectric generation film, solar panels and energy-storage battery connect, and energy-storage battery is connect with micro air pump.
2. a kind of kit for being applicable in CAR-T cell detection according to claim 1, which is characterized in that the cooling piece Using semiconductor chilling plate.
3. a kind of kit for being applicable in CAR-T cell detection according to claim 1, which is characterized in that the box body two Side is recessed installation space, and cell wall and lower cell wall constitute the installation of solar panels, thermoelectric generation film, cooling piece in further groove Bracket.
4. a kind of kit for being applicable in CAR-T cell detection according to claim 1, which is characterized in that the energy storage electricity Pond is located at box body bottom.
5. a kind of kit for being applicable in CAR-T cell detection according to claim 1, which is characterized in that in the box body If heat detector.
6. a kind of kit for being applicable in CAR-T cell detection according to claim 1, which is characterized in that the reagent bottle It is convex under frame bottom, and its middle part indent, bottom is convex in corresponding box body, is fitted and fixed with.
CN201822256238.7U 2018-12-29 2018-12-29 A kind of kit being applicable in CAR-T cell detection Active CN209412194U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201822256238.7U CN209412194U (en) 2018-12-29 2018-12-29 A kind of kit being applicable in CAR-T cell detection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201822256238.7U CN209412194U (en) 2018-12-29 2018-12-29 A kind of kit being applicable in CAR-T cell detection

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CN209412194U true CN209412194U (en) 2019-09-20

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112175821A (en) * 2020-10-12 2021-01-05 赖仕川 Biological self-regulation passive constant-temperature incubator

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112175821A (en) * 2020-10-12 2021-01-05 赖仕川 Biological self-regulation passive constant-temperature incubator

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