CN209377635U - The replaceable living body sampler of sampling head - Google Patents

Abstract

The utility model relates to a kind of living body samplers that sampling head is replaceable.The replaceable living body sampler of sampling head includes hand-held frame, sampling cannula is installed on hand-held frame, sampling inserted link is installed in sampling cannula, sampling cannula can be relative to sampling inserted link axial movement, sample inserted link end it is replaceable sampling head is installed, sampling head has the accommodation space for accommodating tissue sample.The replaceable living body sampler of the sampling head avoids the occurrence of generating cross-infection between different living bodies by replacing sampling head after the completion of each sampling, and the sampling head removed can integrally be put into freezing vessel and save, guarantee that cell tissue takes out the sterility requirements of process, it enables an operator to smoothly collect required tissue sample, it is very useful.

Description

The replaceable living body sampler of sampling head

Technical field

The equipment technology field that the utility model relates to sample for active somatic cell, and in particular to a kind of sampling head is replaceable Living body sampler.

Background technique

Clinical due to scientific research and medical diagnosis on disease needs, and generally requires to carry out living body sampling to animal tissue, as liver, kidney, The tissue such as mammary gland, muscle and tumour, in the prior art, mostly uses greatly sampler to be acquired the animal tissue of required acquisition Sampling.

A kind of tissue sampling device as disclosed in the Chinese utility model patent that Authorization Notice No. is CN204789014U, should Tissue sampling device includes the needle core sampling component extended along the longitudinal direction, and needle core sampling component includes guiding movement along the longitudinal direction The needle core and needle tubing of suit, needle core front end are equipped with syringe needle, and needle core rear end cap is equipped with for applying forward active force to needle tubing Reset spring is additionally provided on needle core for sampling section to the tissue of tissue sampling, tissue sampling section outer peripheral surface be equipped with sample it is recessed Slot, the annular end face of needle tubing front end are equipped with the dentation cutting blade of annular.The tissue sampling device is when carrying out tissue sampling, by needle core Sampling component is pierced into forward in the tissue of sampling, then overcomes the active force post-tensioning needle tubing of reset spring, exposes adopting on needle core Sample groove falls into structural portion of tissue sample in sampling groove, reset spring is unclamped, by the annular dentation of needle tubing front end Cutting blade cuts tissue junction, and cutting enters the tissue in sampling groove, finally takes out tissue sampling device from sampling body.

The sampling groove of above-mentioned tissue sampling device is smaller, is not easy to take the cell tissue sampled in groove after the completion of sampling Completely；When being sampled using the tissue sampling device to other end animal, once a upper animal is adulterated in sampling groove Cell tissue, even if being also difficult to avoid that between the animal of both ends to the processing that carries out disinfection of sampling groove and generating cross-infection, in this way It can carry out very big injury to lead for animal；In addition, the sterility requirements that the cell tissue sampled in groove takes out process are also difficult to protect Card, needs to carry out disinfection to the freezing vessel for holding sampling tissue, and needs to for taking out the groups of cells in sampling groove The tool knitted carries out disinfection processing, when sampling that animal head number is more or sampling quantity is big, it is difficult to ensure that operator is every time to adopting Sample groove, tool, freezing vessel and dentation cutting blade carry out thorough disinfection processing, this is difficult to the cell tissue for guaranteeing to take every time It meets the requirements.

Utility model content

The purpose of this utility model is to provide a kind of living body samplers that sampling head is replaceable, to solve in the prior art Living body sampling apparatus when reusing, it is difficult to avoid generating between different living bodies and cross-infection and be difficult to ensure collected The technical issues of tissue sample meets the requirements.

To achieve the above object, the technical solution of the utility model is: the replaceable living body sampler of sampling head, including hand Frame is held, sampling cannula is installed on hand-held frame, sampling inserted link is installed in sampling cannula, sampling cannula can be relative to sampling inserted link Axial movement, sample inserted link end it is replaceable sampling head is installed, sampling head has the accommodation space for accommodating tissue sample.

The beneficial effect of the replaceable living body sampler of sampling head is: the replaceable work of sampling head provided by the utility model The sampling plunger end of sampler body device it is replaceable sampling head is installed, and sampling head has the receiving for accommodating tissue sample Space, after the completion of primary sampling, can dismantle sampling head the sampling head more renewed, and the sampling head removed integrally is placed on freezing It is saved in vessel.When sampling to different living bodies, it is all made of new sampling head, avoiding problems because taking after sampling every time Tissue sample in sample head accommodation space be difficult to handle it is clean and when reusing caused by between difference living body cross-infection show The generation of elephant, to will not be damaged to living body；Meanwhile the sampling head removed integrally is put into freezing vessel and saves, and avoids Using specialist tools the tissue sample in sampling head accommodation space is fetched into the process saved again in freezing vessel, protected Satisfactory tissue sample can be obtained when having demonstrate,proved the sterility requirements that cell tissue takes out process, therefore having sampled every time.

Further, the replaceable living body sampler of sampling head includes handheld drill rifle, described in the shell of handheld drill rifle is constituted Hand-held frame, sampling cannula are mounted on shell, and the shaft of handheld drill rifle connect with sampling inserted link and sampling inserted link can be driven around certainly Body axis rotation, sampling head are drill bit, and drill bit has the cutting edge for cutting living body surface texture when rotated, and drill bit is in cutting edge Rear side be equipped with the accommodation space.

Beneficial effect is: drill bit is a kind of concrete form of sampling head, and drill bit can be rotated together with sampling inserted link, utilizes brill Living body surface texture is cut in the accommodation space of rear side by the cutting edge on head, is easy batch production in the prior art, i.e., After the completion of each sampling, directly more bit change can integrally take out the accommodation space for accommodating tissue sample, very convenient.

Further, the drill bit is threadedly coupled with the sampling inserted link, and drill bit is inserted in the accommodation space and with sampling Bar is equipped between being threadedly coupled and screws section.

Beneficial effect is: being threadedly coupled between drill bit and sampling inserted link, convenient for fastening between the two；Drill bit, which has, to screw Section screws section and is located on rear side of accommodation space, i.e., far from the cutting edge of drill bit, is convenient for manual operation, operator is protected not cut Sword scuffing is cut, section is screwed simultaneously close to the threaded connection place of the two, conveniently manually screws to dismount drill bit.

Further, the drill bit has external screw thread linkage section, and the sampling inserted link has internal screw thread linkage section, the rotation Twisting section is the column structure that outer diameter is greater than the external screw thread linkage section.

Beneficial effect is: drill bit have external screw thread linkage section, screw section outer diameter be greater than external screw thread linkage section outer diameter, one Aspect can reduce the size that drill bit is used to be threadedly coupled part, in addition be also convenient for manually screwing, more laborsaving when screwing.

Further, the outer surface of column structure is equipped with annular knurl.

Beneficial effect is: annular knurl can increase the roughness for screwing section outer surface, consequently facilitating manually screwing.

Further, the diameter for installing bolt under external force to dismount the drill bit is additionally provided on column structure To perforation.

Beneficial effect is: bolt can be penetrated in radial perforation, and section is screwed to realize by manual rotation's bolt, thus Drill bit is dismantled, it is easy to operate.

Detailed description of the invention

Fig. 1 is the stereochemical structure oblique view of the replaceable living body sampler of sampling head provided by the utility model；

Fig. 2 is the stereochemical structure main view of the replaceable living body sampler of sampling head provided by the utility model；

Fig. 3 is the stereochemical structure top view of the replaceable living body sampler of sampling head provided by the utility model；

Fig. 4 is the B-B cross-sectional view of Fig. 3；

Fig. 5 is the stereochemical structure right view of the replaceable living body sampler of sampling head provided by the utility model；

Fig. 6 is the A-A cross-sectional view (saving data line, fixing clamp and spherical hinge structure) of Fig. 5；

Fig. 7 is the enlarged drawing in Fig. 6 at A；

Fig. 8 is the stereochemical structure signal of the drill bit in the replaceable living body sampler of sampling head provided by the utility model Figure.

In figure: 1- handheld drill rifle, 2- shell, 3- drill bit, 4- sampling cannula, 5- sample inserted link, 6- closing in tapered sleeve, 7- necking Casing, 8- needle tubing probe, 9- guide sleeve, 10- photographic device, 11- mounting base, 12- rack gear, 13- fixing clamp, 14- adjusting knob, 15- spherical hinge structure, 16- data line, 17- drill bit shaft, 18- partition, 19- cutting tip, 20- external screw thread linkage section, 21- connection Block, 22- storage sample chamber, 23- perforation, 24- cutting edge, 25- screw section.

Specific embodiment

The embodiments of the present invention is described further with reference to the accompanying drawing.

The specific embodiment of the replaceable living body sampler of sampling head provided by the utility model, as shown in Figures 1 to 6, The replaceable living body sampler of the sampling head includes handheld drill rifle 1, and handheld drill rifle 1 forms the hand-held frame held for operator, Sampling cannula 4 is installed, the rotation pipette tips position of handheld drill rifle 1 is connected with sampling inserted link 5, sampling on the shell 2 of handheld drill rifle 1 The end of inserted link 5 it is replaceable sampling head is installed, sampling head has the accommodation space for accommodating tissue sample.In the present embodiment, Sampling head is the drill bit 3 for being removably mounted on the sampling one end of inserted link 5 far from handheld drill rifle 1.Sampling cannula 4 is set in sampling Outside inserted link 5, and can relative sample inserted link 5 be axially moveable, so as to adjust drill bit 3 expose sampling cannula 4 length.Hand The necking casing 7 and closing in tapered sleeve 6 being equipped on the shell 2 for boring rifle 1 for locking sampling cannula 4 are held, wherein necking casing 7 fills Fit on the shell 2 of handheld drill rifle 1, sampling inserted link 5 is passed through out of necking casing 7,4 sets of sampling cannula it is outer in sampling inserted link 5 and In the rear end insertion necking casing 7 of sampling cannula 4, the adjustable in length being inserted into necking casing 7 by adjusting sampling cannula 4 is bored First 3 expose the length of sampling cannula 4.Necking casing 7 is connected with closing in tapered sleeve 6 by screw threads for fastening, by screwing closing in tapered sleeve 6, so that closing in tapered sleeve 6 squeezes necking casing 7 so that the elastic claw of necking casing 7, which clamps sampling cannula 4, realizes sampling cannula 4 Locking.

As shown in Figure 7 and Figure 8, drill bit 3 includes cutting tip, and cutting tip includes drill bit shaft 17 and is arranged in drill bit shaft 17 The cutting tip 19 of front end, cutting tip 19 have the cutting edge 24 and back of the cutting living body surface texture when drill bit 3 rotates The partition 18 that the axis along drill bit shaft 17 from cutting edge 24 extends, surrounds between the inside and sampling cannula 4 of cutting tip 19 For accommodating the storage sample chamber 22 of tissue sample, storage sample chamber 22 is located at the rear side of cutting edge 24, does not have to put in living body group in cutting Inside is knitted, to reduce the wound to living body.Drill bit 3 further includes the bit adapter that the rear end of drill bit shaft 17 is arranged in, tool Body, bit adapter is external screw thread linkage section 20.As shown in Figure 4 and Figure 6, the front end for sampling inserted link 5 is link block 21, connection Block 21 is equipped with the groove of indent, has internal screw thread linkage section in groove, drill bit 3 by external screw thread linkage section 20 thereon with adopt Internal screw thread linkage section on sample inserted link 5 is threadedly engaged, and the thread rotary orientation of the external screw thread linkage section 20 of drill bit 3 and sampling inserted link 5 On internal screw thread linkage section thread rotary orientation on the contrary to further realize the fastening of drill bit 3.

Drill bit 3 is equipped between storage sample chamber 22 and external screw thread linkage section 20 and screws section 25, and screwing section 25 is column structure, and And outer diameter can be very laborsaving by screwing manually when dismantling drill bit 3 greater than the outer diameter of external screw thread linkage section 20, and screw 25 cutting edges 24 far from drill bit 3 of section will not be cut the scuffing of sword 24 when manually screwing；Be in the form of a column structure screws the outer of section 25 Surface is equipped with annular knurl, i.e. rolling decorative pattern, and the roughness for screwing 25 outer surface of section can be increased by rolling decorative pattern, i.e., is manually screwing When the phenomenon that rubber sleeve is less likely to occur and can not turn；In order to be more convenient disassembly drill bit 3, perforation is radially provided with screw section 25 23, perforation 23 in can install bolt, then rotated by manual rotation's bolt and screw section 25, so as to drill bit 3 of dismantling with more The drill bit renewed.

As shown in Figure 4 and Figure 6, the replaceable living body sampler of sampling head further includes being movably arranged on sampling cannula 4 Modulator is rotatably equipped with adjusting knob 14 in the mounting base 11 of modulator, and the inner end of adjusting knob 14 is equipped with gear, and sampling is inserted The outer tube wall of pipe 4 is equipped with the rack gear 12 being adapted to gear, is just able to drive mounting base 11 by rotation of adjustment knob 14 and is adopting Movement in sample intubation 4.The needle tubing probe 8 parallel with sampling cannula 4 is fixed in mounting base 11, to avoid mounting base 11 from adjusting Needle tubing probe 8 shakes back and forth when section, and the guide sleeve passed through for needle tubing probe 8 to be oriented to it is equipped on sampling cannula 4 9.The front end of needle tubing probe 8 is equipped with photographic device 10, and photographic device 10 includes headlamp and miniature webcam, miniature video camera Head is connected with the observation device for showing the visible character of living tissue by data line 16, and observation device can be mobile phone, It can be display screen, computer, as long as can show the external character of living tissue.The position for adjusting mounting base 11, can Image size captured by miniature webcam is adjusted, consequently facilitating operator observes more suitable image.Mounting base 11 Top is hinged with fixing clamp 13 by spherical hinge structure 15, and fixing clamp 13 is used to clamp above-mentioned observation device, wherein flexural pivot knot Structure 15 includes the support being fixed in mounting base 11 and fixed hinged ball on the support, and fixing clamp 13 includes straight with hinged ball The casing of diameter adaptation, can be adjusted flexibly the position of fixing clamp 13, by spherical hinge structure 15 in order to the observation of operator.

When in use, living body sampler is inserted into animal body for the living body sampler, by adjusting the position of mounting base 11, Under the assistance of miniature webcam, the purpose tissue for needing to sample more accurately is found, and drill bit 3 is finally made to be adjacent to purpose group Knit surface；Handheld drill rifle 1 is opened, drives drill bit 3 to be rotated, the cutting edge 24 of cutting tip 19 will organized on drill bit 3 Surface carries out cutting sampling, and since storage sample chamber 22 is at the rear portion of cutting edge 24, the fragment of tissue cut can be cut from two The gap that interval between blade 19 is formed enters in the storage sample chamber 22 for accommodating tissue sample along partition 18.

After the completion of cutting, handheld drill rifle 1 is closed, screws closing in tapered sleeve 6, and insert along the sampling of the axis pusher of necking casing 7 Pipe 4 is to adjust the length that sampling cannula 4 is inserted into necking casing 7, until drill bit 3 is completely exposed except sampling cannula 4；Lead to later It receives and distributes to twist and screws section 25 or screw section 25 by being inserted into bolt in perforation 23, drill bit 3 is back-outed from link block 21；It bores First 3 dismantle after be integrally put into freezing vessel and save together with tissue sample thereon.Since the surface of sampling cannula 4 is smooth, The tissue sample on 4 tube wall of sampling cannula is splashed in cutting process can be directly by carrying out at cleaning and disinfection sampling cannula 4 Reason is fallen, i.e., sampling cannula 4 is reusable.When carrying out living body sampling to another animal, installed in sampling 5 front end of inserted link New drill bit repeats above step, i.e., after the completion of primary sampling, drill bit 3 is twisted off, is put into togerther freezer unit together with tissue sample Ware saves, then changes another unsampled drill bit, adjusts to stand-by state, can resampling, be both avoided that difference in this way Cross-infection between living body, and can save the time, guarantee that cell tissue takes out the sterility requirements of process, collects satisfactory Tissue sample.

In the above-described embodiments, drill bit and sampling inserted link pass through the replacement that the structure being threadedly engaged realizes drill bit, at other In embodiment, drill bit and sampling inserted link can also pass through the replacement of other structures form realization drill bit.Such as:

The first, the groove grafting on the bit adapter and sampling inserted link front end link block of drill bit, the mating place of the two Radial direction through a fastening screw make drill bit and sampling inserted link fastening be assembled together, after the completion of cutting, unclamp lock Casing, mobile sampling cannula expose drill bit and fastening screw, and fastening screw is back-outed from sampling inserted link, then can be drill bit It extracts；

Second, the outer surface that sampling inserted link front end link block and drill bit screw section is made into helicitic texture, and the two Thread rotary orientation on the contrary, bit adapter and sampling inserted link front end link block on groove grafting after, set one in the outside of the two A thread bush makes drill bit and sampling inserted link fastening be assembled together by rotary screwing thread set；After the completion of sampling, locking is unclamped Casing simultaneously moves backward sampling cannula and exposes drill bit and thread bush, reversed rotary screwing thread set and then can lay down drill bit；

The third, by the structure for screwing section and being made into spring detent of drill bit, spring detent is equipped with block protrusion, before sampling inserted link The card slot with the cooperation of the block protrusion block of spring detent is offered on the groove two sides inner wall of the link block at end, and spring detent is clutched Shrink it so that bit adapter is slowly inserted into groove, the block protrusion on spring detent is stuck in card slot, trip spring Pawl realizes drill bit and samples the fastening assembly of inserted link；After the completion of sampling, clutching spring detent makes its contraction, makes the gear on spring detent Only protrusion is detached from card slot, slowly takes out drill bit from groove.

In above-described embodiment, the rear portion of the cutting edge of drill bit on it is equipped with accommodation space, in other embodiments, drill bit Augers can also be used, is formed between the helicla flute on the helical blade and augers of augers and accommodates tissue sample Accommodation space, or do not use drill bit, sampling inserted link be made into needle tubing shape, opens up holding tank in the outer surface of inserted link to accommodate Tissue sample.

Claims (6)

1. the replaceable living body sampler of sampling head, it is characterised in that: including hand-held frame, sampling cannula is installed on hand-held frame, Sampling inserted link is installed, sampling cannula can be relative to sampling inserted link axial movement, and the end for sampling inserted link can be more in sampling cannula That changes is equipped with sampling head, and sampling head has the accommodation space for accommodating tissue sample.

2. the replaceable living body sampler of sampling head according to claim 1, it is characterised in that: the replaceable work of sampling head Sampler body device includes handheld drill rifle, and the shell of handheld drill rifle constitutes the hand-held frame, and sampling cannula is mounted on shell, handheld drill The shaft of rifle connect with sampling inserted link and sampling inserted link can be driven to rotate around own axes, and sampling head is drill bit, and drill bit has The cutting edge of living body surface texture is cut when rotation, drill bit is equipped with the accommodation space in the rear side of cutting edge.

3. the replaceable living body sampler of sampling head according to claim 2, it is characterised in that: the drill bit is adopted with described Sample inserted link is threadedly coupled, and drill bit screws section in the accommodation space and with sampling to be equipped between inserted link is threadedly coupled.

4. the replaceable living body sampler of sampling head according to claim 3, it is characterised in that: the drill bit has outer spiral shell Line linkage section, the sampling inserted link have internal screw thread linkage section, and the section that screws is that outer diameter is greater than the external screw thread linkage section Column structure.

5. the replaceable living body sampler of sampling head according to claim 4, it is characterised in that: the outer surface of column structure It is equipped with annular knurl.

6. the replaceable living body sampler of sampling head according to claim 4 or 5, it is characterised in that: on column structure also Equipped with the radial perforation for installing bolt under external force to dismount the drill bit.