CN209332075U - Die body - Google Patents
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- CN209332075U CN209332075U CN201820978468.1U CN201820978468U CN209332075U CN 209332075 U CN209332075 U CN 209332075U CN 201820978468 U CN201820978468 U CN 201820978468U CN 209332075 U CN209332075 U CN 209332075U
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Abstract
The utility model relates to a kind of die body, the die body includes: shell and hollow body；The enclosure interior forms cavity, and the cavity is used to fill the substance of the first image mode imaging；The hollow body is set in the cavity that the enclosure interior is formed, the hollow body includes multiple hollow body sections, at least two hollow body sections are arranged in different spaces plane in multiple hollow body sections, and the hollow body is used to fill the substance of the second image mode imaging.PET image and MR image are calibrated by die body, the coordinate system of PET and MR can be made to be completely coincident, the registration accuracy of PET image and MR image is improved, further increases the image quality of PET/MR equipment.
Description
Technical field
The utility model relates to medical imaging technology fields, more particularly to a kind of mould for multi-modality image registration
Body.
Background technique
In recent decades, multi-modality imaging equipment is receive more and more attention, a large number of studies show that, two or more
Diagnostic can be improved in kind method use in conjunction.Positioning since resolution ratio of the PET to tissue anatomical structure is poor, to lesion
Inaccurate, this limits the popularization and application of PET to a certain extent.PET is widely used in clinic and has benefited from the beginning of this century
The successful development of PET/CT, PET/CT are the medical imaging devices organically combined PET with CT on the same device, are mentioned by CT
For the precise anatomical positioning of lesion, and PET provides the molecular informations such as the detailed function of lesion and metabolism, obtains subject same
Under the conditions of anatomical structure and the image that blends of functional metabolism, have the characteristics that sensitive, accurate, special and registration, one
Secondary image can get whole body faultage image in all directions.
But it is clinical with scientific research in use, PET/CT also exposes many limitations, these limitations are mainly still
Be attributed to the deficiency of CT itself: 1. CT cannot acquire simultaneously image with PET, and the acquisition of PET/CT data is substantially still PET
It is independently carried out with CT two systems；2. CT will lead to the x-ray of higher dosage, be especially unsuitable for pregnant woman, children and be advanced in age and poor in health etc.
It should not receive x-ray examiner.
Therefore, the multimodal device that PET is combined with MR comes into being, and MR has unrivaled advantage relative to CT,
It can be carried out the polyfunctional molecules imaging skill such as Diffusion-Weighted MR Imaging, diffusion tensor imaging, diffusion kurtosis imaging, MR perfusion imaging
Art.Specifically MR is without ionising radiation, the special populations such as particularly suitable children and adolescents and pregnant woman, and the contrast agent of MR
More safe, by partial volume calibration, motion compensation etc., MR can preferably instruct PET image reconstruction, and provide more
Comprehensive overall structure information.The combination of two kinds of equipment of PET and MR can be realized synchronous data collection and make image co-registration, energy
It obtains and more accurately determines the comprehensive information such as organization of human body, function and metabolism, and reduce radiation, this is examined disease is improved
Disconnected and treatment has important value.
In current traditional technology, PET/MR multimodal device when being detected, can be realized synchronous data collection simultaneously
And make image co-registration.But due to the error of hardware installation, PET is caused not exclusively to be overlapped with MR coordinate system, so as to cause PET image
It is poor with the registration accuracy of MR image.Relatively broad method is to carry out PET/MR scanning using die body, then extract scan image
In the obvious point of feature, finally calculate two coordinate systems of PET and MRI between coordinate transform, improve PET/MR image registration essence
Degree.
Utility model content
Based on this, it is necessary to for the error due to hardware installation, PET is caused not exclusively to be overlapped with MR coordinate system, thus
The problem for leading to PET image Yu MR image registration accuracy difference provides a kind of die body for multi-modality image registration.
The utility model provides a kind of die body, and the die body includes: shell and hollow body；The enclosure interior forms sky
Chamber, the cavity are used to fill the substance of the first image mode imaging；The hollow body is set to what the enclosure interior was formed
In cavity, the hollow body includes multiple hollow body sections, and at least two hollow body sections are arranged in not in multiple hollow body sections
Isospace plane, the hollow body are used to fill the substance of the second image mode imaging.
The shell is cylinder in one of the embodiments, and the cylinder includes upper bottom surface, bottom surface and side；
It is connected between the upper bottom surface and/or the bottom surface and the side by cambered surface.
The die body in one of the embodiments, further include: support construction；The support construction and the shell connect
It connects, for carrying the shell.
The ratio between the internal volume that the internal volume and the shell that the hollow body is formed in one of the embodiments, are formed
Range are as follows: 0.1-0.9.
At least one hollow body section of the hollow body is connect in end with the shell in one of the embodiments,.
At least one hollow body section of the hollow body is detachably connected with the shell in one of the embodiments,.
It is provided with aperture at least one hollow body section of the hollow body in one of the embodiments, it is described hollow
Substance of the body by aperture filling for the imaging of the second image mode.
Multiple hollow body sections are respectively round tube and/or hollow ball in one of the embodiments,.
The basal diameter range of the round tube is 2mm-5mm in one of the embodiments,.
The shell and/or the hollow body are made of plastics in one of the embodiments,.
Above-mentioned die body is by setting shell and hollow body, and wherein the cavity of shell is for filling the imaging of the first image mode
Substance, hollow body is set in the cavity of shell, and hollow body includes multiple hollow body sections, is existed in multiple hollow body sections
At least two hollow body sections are arranged in different spaces plane, and hollow body is used to fill the substance of the second image mode imaging.Pass through
Die body calibrates PET image and MR image, and the coordinate system of PET and MR can be made to be completely coincident, and improves PET image and MR schemes
The registration accuracy of picture further increases the image quality of PET/MR equipment.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model embodiment die body；
Fig. 2 is the structural schematic diagram of another embodiment die body of the utility model；
Fig. 3 is the structural schematic diagram of another embodiment die body of the utility model.
Appended drawing reference: 100 it is shell, 200 is hollow body, 210 is hollow body section, 220 is aperture.
Specific embodiment
It is with reference to the accompanying drawings and embodiments, right in order to which the objects, technical solutions and advantages of the application are more clearly understood
The application is further elaborated.It should be appreciated that specific embodiment described herein is only used to explain the application, not
For limiting the application.
Positron e mission computed tomography (PET) is the more advanced clinical examination image skill of the field of nuclear medicine
Art.It is by certain substance, usually necessary substance in biological life metabolism, such as: glucose, protein, nucleic acid, fatty acid,
Short-life radionuclide (such as 18F, 11C etc.) on label, after injecting human body, radionuclide releases in decay process
Positive electron, a positive electron is buried in oblivion advancing a few tenths of millimeter to after encountering an electronics after several millimeters, to generate
Contrary a pair of of energy is the photon of 511KeV.This is to photon, by super-sensitive captured by camera, and through computer
It is scattered the correction with random information.By carrying out identical analysis processing to different positive electron, we it is available
The 3-D image of aggregation situation in organism, to achieve the purpose that diagnosis.
Nuclear magnetic resonance check (MR) is placed in human body in special magnetic field, in radio frequency pulse excitation human body
Hydrogen nuclei causes hydrogen nuclei to resonate, and absorbs energy.After stopping radio-frequency pulse, hydrogen nuclei is issued by specific frequency
Electric signal, and the energy of absorption is released, it is included by external recipient, is handled through electronic computer and obtain image,
This is just called Magnetic resonance imaging.Nuclear magnetic resonance check thoroughly gets rid of damage of the ionising radiation to human body, and has that parameter is more, letter
Breath amount is big, multi-faceted can be imaged, and has the characteristics that high resolution etc. is prominent to soft tissue, is widely used in examining for clinical disease
It is disconnected, essential inspection method is become to some lesions.
Fig. 1-3 is please referred to, Fig. 1 is the structural schematic diagram of the utility model embodiment die body；Fig. 2 is that the utility model is another
The structural schematic diagram of embodiment die body；Fig. 3 is the structural schematic diagram of another embodiment die body of the utility model.
As shown in Figure 1-3, a kind of die body, the die body includes: shell 100 and hollow body 200；Inside the shell 100
Cavity is formed, the cavity is used to fill the substance of the first image mode imaging；The hollow body 200 is set to the shell
In the cavity that 100 inside are formed, the hollow body 200 includes multiple hollow body sections 210, in multiple hollow body sections 210 extremely
Few two hollow body sections 210 are arranged in different spaces plane, and the hollow body 200 is used to fill the object of the second image mode imaging
Matter.
Specifically, filled with the substance for the imaging of the first image mode in shell 100, wherein the first image mode is magnetic
Resonance image-forming mode.Specifically, the substance of the first image mode imaging is the substance of magnetic resonance imaging.The object of magnetic resonance imaging
Matter is the solvent containing hydrogen atom, and more specifically, the substance for the imaging of the first image mode can be nickel sulfate solution.Shell
100 can have any shape, and only need its substance and hollow body 200 with cavity for filling the imaging of the first image mode i.e.
It can.Due to the imaging characteristics of magnetic resonance, the sharp borders of shell 100 are fewer, and imaging effect is better, it is therefore preferable that shell
Body 100 can be cylinder, and the cylinder includes upper bottom surface, bottom surface and side；The upper bottom surface and/or the bottom surface
It is connect between the side by cambered surface.Specifically, can be connected between upper bottom surface and the side by cambered surface；It can also
Think and is connected between bottom surface and the side by cambered surface；It can also be logical between upper bottom surface and bottom surface and the side
Cross cambered surface connection.Cambered surface connection reduces the sharp borders of shell 100, keeps its imaging effect more preferable, it is easier to differentiate.Hollow body
200 can have any shape, only need to be in the structure of hollow body 200 with the straight line of two antarafacials.Preferably, hollow body
200 may include multiple hollow body sections 210.Hollow body section 210 can be round tube and be also possible to hollow ball, and multiple hollow
Round tube can be only included in body section 210；Hollow ball can also be only included；It can also not only include round tube but also include hollow ball.
210 antarafacial of wherein at least two hollow body section, and be connected to by another hollow body section 210.At least the one of the hollow body 200
Aperture 220 is provided in a hollow body section 210, the hollow body 200 is used for the second image mode by the aperture 220 filling
The substance of imaging.Multiple hollow body sections 210, which are connected, can reduce the opening number being arranged in hollow body section 210, reduce hollow
The opening number being arranged in body section 210 is further avoided in the substance for carrying out the second image mode imaging to hollow body 200
A possibility that bubble generated when perfusion.The setting of at least two hollow body sections, 210 antarafacial can make nuclear imaging and magnetic resonance imaging
It is not identical in the cross sectional image that different directions generate die body, to make being registrated more for nuclear imaging image and magnetic resonance image
It is accurate.Filled with the substance for the imaging of the second image mode in hollow body 200.Wherein the second image mode is nuclear imaging.
Substance for the imaging of the second image mode is the glucose that Short-lived radionuclide is marked, protein, nucleic acid, fatty acid
It include such as Deng, short-life radionuclide18F、11C etc..Preferably, de- for fluoro for the substance of the second image mode imaging
Oxygen glucose.Hollow body 200 is set in the cavity of shell 100, and the size of hollow body 200 is less than the size of shell 100, makes sky
Heart body 200 can be fully seated in shell 100.Wherein hollow body 200 can connect with shell 100 and can also be not connected to, only
Needing to guarantee to be perfused component 200 can be fully seated in shell 100.
Preferably, at least one hollow body section 210 of the hollow body 200 is connect in end with the shell 100.
Specifically, at least one hollow body section 210 of the hollow body 200 is detachably connected with the shell 100.Wherein
Two bottom surfaces that shell 100 can be born against for the both ends of hollow body section 210 are detachably connected, so that hollow body 200 be consolidated
Due in 100 cavity of shell.It is detachably connected or the one or both ends of hollow body section 210 can by buckle or screw thread etc.
The connection type of disassembly is connect with the bottom surface of shell 100, is fixed in 100 cavity of shell from by hollow body 200.Hollow body 200
It may be to be fixedly connected with shell 100, being fixedly connected to be shell 100 and the integrated molding of hollow body 200 etc..
Preferably, aperture 220, the hollow body are provided at least one hollow body section 210 of the hollow body 200
200 substance by the aperture 220 filling for the imaging of the second image mode.
Specifically, it is provided with aperture 220 in hollow body section 210, for being perfused into hollow body 200 for the second imaging mould
The substance of state imaging, for example, fluorodeoxyglucose (fluorodeoxyglucose, FDG).Wherein, aperture 220 can be set
In a hollow body section 210, aperture 220 can also be respectively set in multiple hollow body sections 210.The setting of aperture 220 is existed
In one hollow body section 210 and multiple hollow body sections 210 are interconnected, it is possible to reduce the imaging of the second image mode is being perfused
When substance, the bubble of generation in hollow body 200.And aperture 220 is respectively set in multiple hollow body sections 210, relative at one
Aperture 220, which is arranged, in hollow body section 210 can accelerate the speed that the substance of the second image mode imaging is perfused.
Preferably, the die body further include: support construction；The support construction is connect with the shell 100, for carrying
The shell 100.
Specifically, when carrying out multi-modality image registration using die body, it is necessary first to which multimodal device sweeps die body
It retouches, acquisition scans data, and is based on scan data reconstruction die body image.It is scanning bed for the ease of die body to be stably placed at
On, shell 100 is carried by setting support construction, so as to can be stably placed on scanning bed.
Preferably, the hollow body section 210 is round tube, and bottom surface or cross-sectional diameter range are 2mm-5mm.
Preferably, the range of the ratio between the internal volume that the internal volume and the shell 100 that the hollow body 200 is formed are formed
Are as follows: 0.1-0.9.
Preferably, shell 100 and hollow body 200 can be made of a plurality of types of materials, and the material of shell 100 needs to have
Have certain rigidity, be not susceptible to deformation, at the same between the substance and hollow body 200 that are imaged for the first image mode not
Generation is physically or chemically reacted；Similarly, the rigidity that the material of hollow body 200 needs to have certain, is not susceptible to deformation, while with
For the imaging of the second image mode substance and with do not occur physically or chemically between the substance that is imaged for the first image mode
Reaction.More specifically, shell 100 and hollow body 200 can be plastic material.
Above-mentioned die body setting shell and hollow body, wherein in the cavity of shell filled with for the first image mode at
The substance of picture, hollow body are set in the cavity of shell, and hollow body is divided into multiple hollow body sections, multiple hollow body sections
Middle there are at least two hollow body sections to be arranged in different spaces plane, is filled in hollow body for the imaging of the second image mode
Substance.PET image and MR image are calibrated by die body, the coordinate system of PET and MR can be made to be completely coincident, improves PET
The registration accuracy of image and MR image further increases the image quality of PET/MR equipment.
Die body is stated in use PET/MR equipment to be carried out die body is placed on the scanning bed of PET/MR equipment on time
On, starting PET/MR equipment is scanned die body, generates PET image respectively and MR image, PET image are nuclear imaging apparatus
The image that the substance scanning of second image mode imaging is generated；MR image is that the first image mode is imaged in magnetic resonance equipment
The image that substance scanning generates, the imaging section split-phase of PET image Yu MR image is known that according to PET/MR image registration die body
The positional relationship answered, therefore PET image can be registrated with MR image by least three non-coplanar pixels, it obtains
Calibration coordinate transformation, to achieve the purpose that PET image and MR image calibration.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
Above-described embodiments merely represent several embodiments of the utility model, the description thereof is more specific and detailed,
But it cannot be understood as the limitations to utility model patent range.It should be pointed out that for the common skill of this field
For art personnel, without departing from the concept of the premise utility, various modifications and improvements can be made, these are belonged to
The protection scope of the utility model.Therefore, the scope of protection shall be subject to the appended claims for the utility model patent.
Claims (10)
1. a kind of die body, which is characterized in that the die body includes: shell and hollow body；
The enclosure interior forms cavity, and the cavity is used to fill the substance of the first image mode imaging；
The hollow body is set in the cavity that the enclosure interior is formed, and the hollow body includes multiple hollow body sections, multiple
At least two hollow body sections are arranged in different spaces plane in the hollow body section, and the hollow body is for filling the second imaging mould
The substance of state imaging.
2. die body according to claim 1, which is characterized in that the shell be cylinder, the cylinder include upper bottom surface, under
Bottom surface and side；It is connected between the upper bottom surface and/or the bottom surface and the side by cambered surface.
3. die body according to claim 1, which is characterized in that the die body further include: support construction；
The support construction is connect with the shell, for carrying the shell.
4. die body according to claim 1, which is characterized in that the internal volume that the hollow body is formed is formed with the shell
The ratio between internal volume range are as follows: 0.1-0.9.
5. die body according to claim 1, which is characterized in that at least one hollow body section of the hollow body end with
The shell connection.
6. die body according to claim 5, which is characterized in that
At least one hollow body section and the shell of the hollow body are detachably connected.
7. die body according to claim 1, which is characterized in that be provided at least one hollow body section of the hollow body
Aperture, the substance that the hollow body is imaged by aperture filling for second image mode.
8. die body according to claim 1, which is characterized in that
Multiple hollow body sections are respectively round tube and/or hollow ball.
9. die body according to claim 8, which is characterized in that
The basal diameter range of the round tube is 2mm-5mm.
10. die body according to claim 1, which is characterized in that
The shell and/or the hollow body are made of plastics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820978468.1U CN209332075U (en) | 2018-06-22 | 2018-06-22 | Die body |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820978468.1U CN209332075U (en) | 2018-06-22 | 2018-06-22 | Die body |
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| Publication Number | Publication Date |
|---|---|
| CN209332075U true CN209332075U (en) | 2019-09-03 |
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ID=67744455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820978468.1U Active CN209332075U (en) | 2018-06-22 | 2018-06-22 | Die body |
Country Status (1)
| Country | Link |
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| CN (1) | CN209332075U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111345836A (en) * | 2020-03-06 | 2020-06-30 | 济南华宇新铸锻材料有限公司 | CT/MR customized image omics quality control die body |
| CN112494138A (en) * | 2020-11-16 | 2021-03-16 | 上海全景医学影像诊断中心有限公司 | Die body for MR-DTI |
-
2018
- 2018-06-22 CN CN201820978468.1U patent/CN209332075U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111345836A (en) * | 2020-03-06 | 2020-06-30 | 济南华宇新铸锻材料有限公司 | CT/MR customized image omics quality control die body |
| CN112494138A (en) * | 2020-11-16 | 2021-03-16 | 上海全景医学影像诊断中心有限公司 | Die body for MR-DTI |
| CN112494138B (en) * | 2020-11-16 | 2021-10-01 | 上海全景医学影像诊断中心有限公司 | Die body for MR-DTI |
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| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 201807 Shanghai City, north of the city of Jiading District Road No. 2258 Patentee after: Shanghai Lianying Medical Technology Co., Ltd Address before: 201807 Shanghai City, north of the city of Jiading District Road No. 2258 Patentee before: SHANGHAI UNITED IMAGING HEALTHCARE Co.,Ltd. |
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| CP01 | Change in the name or title of a patent holder |