CN209322849U - A kind of separating extraction device and separation and Extraction system - Google Patents
A kind of separating extraction device and separation and Extraction system Download PDFInfo
- Publication number
- CN209322849U CN209322849U CN201821554891.5U CN201821554891U CN209322849U CN 209322849 U CN209322849 U CN 209322849U CN 201821554891 U CN201821554891 U CN 201821554891U CN 209322849 U CN209322849 U CN 209322849U
- Authority
- CN
- China
- Prior art keywords
- cabin
- fixator
- liquid
- gun head
- magnet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Sampling And Sample Adjustment (AREA)
Abstract
The utility model provides a kind of separating extraction device and separation and Extraction system, the separating extraction device includes: including pedestal, and the support construction being set on the base, it is provided with moving assembly on the support structure, moving assembly includes fixator, fixator includes adapter, adapter is detachably connected with liquid transfer gun head, fixator is connected to by adapter with the channel being arranged in liquid transfer gun head, fixator is connect with the pump housing by conduit, liquid transfer gun head is set to suck or be discharged liquid, sliding rail is additionally provided on pedestal, sliding rail is slidably connected with fixed frame, kit is provided in fixed frame, kit includes holding liquid tank and waste liquid cabin, it holds liquid tank and useless tank roof is equipped with opening, Ka Gai is equipped in opening, elaxtic seal is provided between lid being open and blocking, magnet is additionally provided on fixed frame, magnet can with adapter Dismantling connection.The device streamline operation, promotion can separate precision in separation and Extraction biomolecular processes.
Description
Technical field
The utility model relates to molecular diagnostic techniques fields, mention in particular to a kind of separating extraction device and separation
Take system.
Background technique
In molecular biology and in-vitro diagnosis field, no matter scientific research demand or clinical diagnosis, be both needed to by quantitative or fixed
Property detection sample in specific biomolecule, such as: specific nucleic acid sequence or certain protein, the inverting of Lai Jinhang biological information and
Medical diagnosis on disease.It under these application demands, acquires and the biological sample that measures often complicated component, the life for needing to detect in addition
Object molecular concentration is often very low, and directly detection is more difficult.
At this stage generally using nanometer magnetic bead method come the scheme of separation and Extraction biomolecule, the program is needed using bar magnet,
Stirring set and corresponding reagent.
But the nanometer magnetic bead for being adsorbed with target biological molecules is repeatedly passed through bar magnet and stirring set lift-off liquid by whole process
Face exposure in air, the possibility for forming aerosol is drifted into air there are target biological molecules, this possibility is to laboratory
There is biological risk in personnel, while can also interfere with subsequent detection.
Utility model content
The purpose of this utility model is that in view of the deficiency of the prior art, provide a kind of separating extraction device and
Separation and Extraction system streamline operation, promotion separation precision can make to purify in separation and Extraction biomolecular processes
The purity of liquid is higher.
To achieve the above object, the utility model embodiment the technical solution adopted is as follows:
In a first aspect, the utility model embodiment provides a kind of separating extraction device, comprising: including pedestal, Yi Jishe
Support construction on the base is set, moving assembly is provided in the support construction, the moving assembly includes fixing
Device, the fixator include adapter, and the adapter is detachably connected with liquid transfer gun head, and the fixator passes through the switching
Head is connected to the channel being arranged in the liquid transfer gun head, and the fixator is connect with the pump housing by conduit, and the liquid transfer gun head is made
Sucking or discharge liquid, are additionally provided with sliding rail, the sliding rail is slidably connected with fixed frame, in the fixed frame on the base
It is inside provided with kit, the kit includes holding liquid tank and waste liquid cabin, and the liquid tank that holds is equipped with the useless tank roof
Opening is equipped with Ka Gai over said opening, elaxtic seal is provided between the opening and card lid, described solid
Determine to be additionally provided with magnet on frame, the magnet can be detachably connected with the adapter.
In a kind of embodiment, the moving assembly further includes Single Mechanical arm, and the Single Mechanical arm and the fixator are solid
Fixed connection.
It further include XYZ dynamical system in a kind of embodiment, the XYZ dynamical system is for controlling the fixed frame point
It is not mobile in Z-direction in X-direction, the movement of Y direction and the control moving assembly.
In a kind of embodiment, the kit further includes reagent storage cabin, first places cabin and second and place cabin, described
Card, which covers to be provided with, holds corresponding two through-holes of liquid tank and the waste liquid cabin with described respectively, it is described hold be provided on liquid tank it is removable
The first protective film unloaded；
The reagent storage cabin includes multiple reagent storage chambers, and the opening of the waste liquid cabin and the reagent storage chamber is solid
Equipped with the second protective film；
The first placement cabin and second placement cabin place liquid transfer gun head respectively and puncture component, described to puncture component
It is detachably connected with the fixator by adapter, being equipped at the top of the first placement cabin and second placement cabin can
The third protective film of disassembly.
In a kind of embodiment, the elaxtic seal includes at least one of silica gel, rubber.
In a kind of embodiment, positioning mark corresponding with the through-hole is provided on the elaxtic seal.
In a kind of embodiment, the two sides in the reagent storage cabin are respectively set that there are two fixed ears.
In a kind of embodiment, the liquid transfer gun head is disposable liquid transfer gun head, and the component that punctures is disposable aspiration needle.
In a kind of embodiment, the magnet is magnet or electromagnet.
Second aspect, the utility model embodiment additionally provide a kind of separation and Extraction system, including anticollision inductor and position
Inductor and separating extraction device as described in relation to the first aspect are set, the anticollision inductor is equipped with and the position sensor is arranged
On the moving assembly.
The beneficial effects of the utility model are:
A kind of separating extraction device provided by the embodiment of the utility model and separation and Extraction system, by holding liquid tank and giving up
The open top of liquid tank is provided with elaxtic seal, so that liquid to be purified is constantly in sealed environment, realizes and is setting
Liquid during received shipment is made is not in leakage and contamination phenomenon, and by setting fixator, which has can be automatic
Load and self-discharging function realize fixator automatic load and unloading liquid transfer gun head, magnet respectively, in addition, magnet is set
It sets and is holding on the outside of liquid tank, magnet is not limited by tank dimension is held, and volume is big, and magnetic bead active area in liquid tank is big with holding, magnetic chamber,
Time-consuming short, effect is good.
Detailed description of the invention
It, below will be to use required in embodiment in order to illustrate more clearly of the technical solution of the utility model embodiment
Attached drawing be briefly described, it should be understood that the following drawings illustrates only some embodiments of the utility model, therefore should not be by
Regard the restriction to range as, for those of ordinary skill in the art, without creative efforts, may be used also
To obtain other relevant attached drawings according to these attached drawings.
Fig. 1 is separating extraction device overall structure diagram provided by the embodiment of the utility model；
Fig. 2 is kit overall structure diagram provided by the embodiment of the utility model；
Fig. 3 is kit side view provided by the embodiment of the utility model；
Fig. 4 is top view provided by the embodiment of the utility model；
Fig. 5 is magnet course of work schematic diagram provided by the embodiment of the utility model；
Fig. 6 is the course of work module map of separating extraction device provided by the embodiment of the utility model.
Icon: 1- separating extraction device；10- holds liquid tank；11- elaxtic seal；12- positioning mark；13- Ka Gai；15- is logical
Hole；The first protective film of 17-；20- waste liquid cabin；The second protective film of 21-；30- reagent storage cabin；31- fixed ear；40- first is placed
Cabin；41- liquid transfer gun head；43- third protective film；50- second places cabin；60- pedestal；70- support construction；80- moving assembly；
81- Single Mechanical arm；83- fixator；84- adapter；90- fixed frame；100- magnet；101- magnet magnetic position；103- magnet is empty
Not busy position；120- kit；The first dynamical system of 121-；The second dynamical system of 123-；125- third dynamical system；The 130- pump housing；
140- conduit；121a- first motor；The first sliding rail of 121b-；The second motor of 123a-；The second sliding rail of 123b-；125a- third electricity
Machine；125b- third sliding rail.
Specific embodiment
It is practical new below in conjunction with this to keep the objectives, technical solutions, and advantages of the embodiments of the present invention clearer
Attached drawing in type embodiment, the technical scheme in the utility model embodiment is clearly and completely described, it is clear that is retouched
The embodiment stated is the utility model a part of the embodiment, instead of all the embodiments.Usually here in attached drawing description and
The component of the utility model embodiment shown can be arranged and be designed with a variety of different configurations.
Therefore, requirement is not intended to limit to the detailed description of the embodiments of the present invention provided in the accompanying drawings below
The scope of the utility model of protection, but it is merely representative of the selected embodiment of the utility model.Based in the utility model
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the range of the utility model protection.
It should also be noted that similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi
It is defined in a attached drawing, does not then need that it is further defined and explained in subsequent attached drawing.
It is in the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", " perpendicular
Directly ", the orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" be based on the orientation or positional relationship shown in the drawings, or
The utility model product using when the orientation or positional relationship usually put, be merely for convenience of description the utility model and letter
Change description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with specific orientation construct and
Operation, therefore should not be understood as limiting the present invention.In addition, term " first ", " second ", " third " etc. are only used for area
Divide description, is not understood to indicate or imply relative importance.
In addition, the terms such as term "horizontal", "vertical" are not offered as requiring component abswolute level or pendency, but can be slightly
Low dip.It is not to indicate that the structure has been had to if "horizontal" only refers to that its direction is more horizontal with respect to for "vertical"
It is complete horizontal, but can be slightly tilted.
In the description of the present invention, it should also be noted that, unless otherwise clearly defined and limited, term " is set
Set ", " installation ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection,
Or it is integrally connected；It can be mechanical connection, be also possible to be electrically connected；It can be directly connected, intermediary can also be passed through
It is indirectly connected, can be the connection inside two elements.For the ordinary skill in the art, it can be managed with concrete condition
Solve the concrete meaning of above-mentioned term in the present invention.
First embodiment
Fig. 1 is please referred to, the utility model embodiment provides a kind of separating extraction device 1, including pedestal 60, and setting exists
Support construction 70 on the pedestal 60, is provided with moving assembly 80 in support construction 70, and moving assembly 80 includes fixator
83, fixator 83 includes adapter 84, and adapter 84 is detachably connected with liquid transfer gun head 41, fixator 83 by adapter 84 and
The channel connection being arranged in liquid transfer gun head 41, fixator 83 are connect with the pump housing 130 by conduit 140, and liquid transfer gun head 41 is sucked
Or discharge liquid, the first sliding rail 121b is additionally provided on pedestal 60, the first sliding rail 121b is slidably connected with fixed frame 90, solid
Determine to be provided with kit 120 in frame 90；
Referring to figure 2., kit 120 includes holding liquid tank 10 and waste liquid cabin 20, holds and is all provided at the top of liquid tank 10 and waste liquid cabin 20
There is opening, card lid 13 is equipped in opening, elaxtic seal 11 is provided between opening and card lid 13, on fixed frame 90
It is additionally provided with magnet 100, magnet 100 can be detachably connected with adapter 84.
In the present embodiment, the adapter 84 being arranged on fixator 83 can be round boss, set on liquid transfer gun head 41
Circular groove, fixator 83 and liquid transfer gun head 41 is equipped with to load and unload automatically by the round boss and the circular groove, it should
Adapter 84 can be magnetically attractive stick, be provided with through-hole on magnet 100, protrudes into the through-hole by the Magnetic suction rod, passes through mutual magnetic
The magnet 100 is fixed with fixator 83 in power.
In the present embodiment, liquid tank 10 and waste liquid cabin 20 are held and is equipped with concordant opening, therefore, entirety can be passed through
Elaxtic seal 11 and Ka Gai 13 seal the opening for holding liquid tank 10 Yu waste liquid cabin 20 together, can play save material in this way
Effect, the uneven opening of height can also be equipped with by holding liquid tank 10 and waste liquid cabin 20, be blocked by two elaxtic seals 11 and two
Lid 13 seals the opening for holding liquid tank 10 Yu waste liquid cabin 20 respectively, can to hold liquid tank 10, waste liquid cabin 20 in this way at any one
Sealing when something goes wrong, facilitates replacement to repair.It holds as liquid tank 10 can be set into the cabin length in waste liquid cabin 20, it can also
It is different to be arranged to, it can specifically be arranged according to the actual situation, in the present embodiment, the length for holding liquid tank 10 compares waste liquid
The length in cabin 20 is short, and the length in waste liquid cabin 20 is the waste liquid cabin in order to guarantee during separating-purifying greater than 10 length of liquid tank is held
20 have enough spaces to place waste liquid.
A kind of separating extraction device provided by the embodiment of the utility model, by the open top for holding liquid tank and waste liquid cabin
It is provided with elaxtic seal, so that liquid to be purified is constantly in sealed environment, is realized in equipment operation
Liquid is not in leakage and contamination phenomenon, and by setting fixator, which, which has, can load automatically and unload automatically
Function, realize fixator automatic load and unloading liquid transfer gun head, magnet respectively, in addition, magnet setting is being held on the outside of liquid tank,
Magnet is not limited by tank dimension is held, and volume is big, and magnetic bead active area in liquid tank is big with holding, magnetic chamber, and time-consuming short, effect is good.
Fig. 1 is please referred to, in the present embodiment, moving assembly 80 further includes Single Mechanical arm 81, Single Mechanical arm 81 and fixator
83 are fixedly connected, and are provided with fluid flow paths in the Single Mechanical arm 81, and one end of the fluid flow paths and conduit 140 connect
Logical, the other end is connected to fixator 83, and the liquid transfer gun head 41 that can be used to control the installation of fixator 83 by using the pump housing 130 is right
Liquid is sucked or is discharged.
Fig. 1 is please referred to, in the present embodiment, which further includes XYZ dynamical system, the XYZ dynamical system
It unites for controlling the fixed frame 90 respectively in X-direction, the movement of Y direction and the control moving assembly 80 in Z axis
Direction is mobile.
Wherein, XYZ dynamical system includes the first dynamical system 121, the second dynamical system 123 and third dynamical system 125,
The XYZ dynamical system primarily to facilitate operation moving assembly 80 and kit 120 with the use of process, three can be provided
The power in a direction, wherein the first dynamical system 121 can provide the power of Y direction, drive kit 120 along the y axis
It moving left and right, the second dynamical system 123 can provide the power of X-direction, and drive kit 120 to be moved forward and backward along the x axis,
Third dynamical system 125 can provide the power of Z-direction, and moving assembly 80 is driven to move up and down along Z-direction, so that
Experimenter can easily carry out purification operations.
Further, in the present embodiment, the first dynamical system 121 includes first motor 121a and the first sliding rail 121b,
Fixed frame 90 is movably set on first motor 121a, fixed frame 90 is slidably connected with the first sliding rail 121b；Second dynamical system
123 include being movably set with fixed frame 90 on the second motor 123a and the second sliding rail 123b, the second motor 123a, fixed frame 90 with
Second sliding rail 123b is slidably connected；Third dynamical system 125 includes third motor 125a and third sliding rail 125b, third motor
It is movably arranged on 125a on Single Mechanical arm 81, Single Mechanical arm 81 is slidably connected with third sliding rail 125b.
Specifically, first motor 121a control fixed frame 90 is slided in the first sliding rail 121b, the second motor 123a control is solid
Determine frame 90 to slide on the second sliding rail 123b, third motor 125a control Single Mechanical arm 81 slides on third sliding rail 125b.
Optionally, which is not limited to arrangement above mode, which can relatively move in spatial position, only
Want to guarantee that kit 120 and moving assembly 80 on fixed frame 90 can cooperate.
Referring to figure 2., in the present embodiment, kit 120 further includes that cabin 40 and second is placed in reagent storage cabin 30, first
Place cabin 50；Be provided on card lid 13 respectively with hold corresponding two through-holes 15 of liquid tank 10 and waste liquid cabin 20, hold and set on liquid tank 10
It is equipped with dismountable first protective film 17；Reagent storage cabin 30 includes multiple reagent storage cabins, the opening of multiple reagent storage chambers
Concordantly, the opening in waste liquid cabin 20 and reagent storage cabin 30 is installed with the second protective film 21；First, which places cabin 40 and second, places
Cabin 50 places liquid transfer gun head 41 respectively and punctures component, and the top in the first placement cabin 40 and the second placement cabin 50 is equipped with detachably
Third protective film 43.
Referring to figure 2. and Fig. 3 holds liquid tank 10, waste liquid cabin 20, the placement cabin of reagent storage cabin 30, first in the present embodiment
40 and second placement cabin 50 can be integrally formed, reagent storage cabin 30 include multiple reagent storage chambers, multiple reagent storage chambers
Cavity length can be set into identical, and how many with specific reference to the amount for needing to place reagent and set, multiple reagent storage chambers can be with
Identical reagent is placed, different reagents can also be placed, can be selected according to the reagent that separating-purifying needs.
The quantity in the first placement cabin 40 and the second placement cabin 50 can be set according to the actual situation, in the present embodiment
In, first, which places cabin 40, includes two placement cabins, and second, which places cabin 50, includes a placement cabin, and the first placement cabin 40 is for placing
Disposable liquid transfer gun head 41, the second placement cabin 50 puncture component for placing, and optionally, the first placement cabin 40 may include multiple the
One places cabin, and multiple placement cabins are placed with disposable liquid transfer gun head 41.
Referring to figure 2., in the present embodiment, it is put with second in the first protective film 17, the first placement cabin 40 held on liquid tank 10
The top for setting cabin 50, which is equipped with the purpose that dismountable third protective film 43 is detachably arranged, allows operator in operation
When can be convenient and open the first protective film 17 and third protective film 43 manually, the second protective film 21 on reagent storage cabin 30 is solid
Surely the purpose being arranged is to guarantee that the reagent inside reagent storage cabin 30 is not contaminated.
Fig. 1 is please referred to, in the present embodiment, elaxtic seal 11 includes at least one of silica gel, rubber, and elasticity is close
Closure material 11 is used to that liquid tank 10 will to be held and waste liquid cabin 20 seals, so that the detection reduced to liquid to be purified is interfered.
It is provided on elaxtic seal 11 corresponding with the through-hole 15 in the present embodiment with Fig. 4 referring to figure 2.
Positioning mark 12, which can be cross, be also possible to the central coordinate of circle of through-hole, can also be the seat with graduation mark
Mark is arranged the purpose of the positioning mark 12 in order to facilitate liquid transfer gun head 41 and holds liquid tank 10 and waste liquid cabin 20 with component positioning is punctured
Position.
Referring to Fig.1 and 2, in the present embodiment, the two sides in reagent storage cabin 30 are respectively arranged with fixed ear 31, this is solid
Ear 31 is determined for kit 120 and fixed frame 90 is fixed.
Fig. 1 is please referred to, in the present embodiment, liquid transfer gun head 41 is disposable liquid transfer gun head, and puncturing component is disposable needle
It manages, the pipeline of connecting tube 140 is provided on the disposable liquid transfer gun head, because separating-purifying is to the degree of purity of liquid to be purified
It is required that it is very high, therefore, for liquid transfer gun head 41 and component is punctured, is all made of disposably, to avoid superinfection, caused inspection
The interference of survey.
Fig. 1 is please referred to, in the present embodiment, the side in fixed frame 90 is placed with magnet 100, another in fixed frame 90
Side is isolated with magnet 100 is provided with kit 120, and the side in fixed frame 90 is placed with magnet 100, places the one of magnet 100
Side can be magnet spare bits 103, and the other side in fixed frame 90 and magnet spare bits 103 are relatively set with magnet magnetic
Position 101, the magnet magnetic position 101 hold that liquid tank 10 is adjacent, and when operating without magnetic, which is to be in this
Magnet spare bits 103, when if necessary to carry out magnetic operation, the magnet 100 can be placed by moving assembly 80
At magnet magnetic position 101, for carrying out magnetic to liquid to be purified.
Referring to figure 5., in the present embodiment, magnet 100 includes magnet or electromagnet, and the magnet 100 in separation for mentioning
Magnetic operation carried out to the liquid that holds in liquid tank 10 in pure procedure, which in the course of work done holding 10 side of liquid tank
Vertical up-or-down movement.
Second embodiment
A kind of separation and Extraction system is being present embodiments provided, including anticollision inductor and position sensor and such as first are in fact
The separating extraction device 1 of example is applied, the anticollision inductor and the position sensor are arranged on the moving assembly 80, described
The specific structure of separating extraction device 1 includes the optional technical solution of whole in first embodiment, at least has first embodiment
Technical solution brought by all beneficial effects.
Anticollision inductor and position sensor are equipped on the Single Mechanical arm 81 of moving assembly 80, which is used for
When the induction of Single Mechanical arm 81 strikes kit 120, control first motor 121a, the second motor 123a and third motor 125a
It stops working, position sensor is used for sensed position signal, control first motor 121a, the second motor 123a and third motor
125a starts or stops work.
Fig. 1 to Fig. 6 is please referred to, experimenter is as follows using the course of work of the separation and Extraction system:
Step 1: taking off film manually, i.e., the first protective film 17 and first that liquid tank 10 is held in kit 120 is first placed into cabin 40
It is opened manually with the third protective film 43 at the top in the second placement cabin 50.
Step 2: being put into kit, i.e., liquid tank 10 is held into the addition of sample liquid manually, and kit 120 is packed into as required
Fixed frame 90.
Step 3: puncturing, first placement cabin 40 moves to the following position directly of fixator 83 in software control kit 120,
The control Single Mechanical arm 81 of third dynamical system 125 drives fixator 83 to move downward and fasten and punctures component, then third power
System 125 controls Single Mechanical arm 81 and fixator 83 is driven to move upwards, when leaving kit 120 wait puncture component bottom end, by list
Location sensitive detection system provides signal in mechanical arm 81, and the second dynamical system 123 is run simultaneously with the first dynamical system 121,
Control kit 120 moves on the second sliding rail 123b and the first sliding rail 121b, then will store reagent in reagent storage cabin 30
Reagent storage chamber and waste liquid cabin 20 move to the underface for installing the fixator 83 for puncturing component additional, 12 determined by positioning mark
Then position controls the fixator 83 that Single Mechanical arm 81 drives installation to puncture component by third dynamical system 125 and moves up and down one by one
It punctures；After the reagent storage chamber of storage reagent and the positioning mark 12 in waste liquid cabin 20 all puncture in candidate agent storage cabin 30, by soft
Second placement cabin 50, which moves to install additional, in part control kit 120 punctures immediately below the fixator 83 of component, third dynamical system 125
The fixator 83 that the control drive installation of Single Mechanical arm 81 punctures component, which moves downwardly to the second placement cabin 50 and unloads, punctures component.
Step 4: cracking, cracking specific steps are as follows:
1. load liquid transfer gun head: third dynamical system 125 controls Single Mechanical arm 81 and fixator 83 is driven to move up, to solid
When determining 83 bottom end of device and leaving kit 120, signal, the second dynamical system are provided by location sensitive detection system in Single Mechanical arm 81
123 control kits 120 are moved in the second sliding rail 123b, until the first placement cabin 40 moves to the underface of fixator 83, third is dynamic
Force system 125 controls Single Mechanical arm 81 and fixator 83 is driven to move down and load liquid transfer gun head 41；
2. adding lytic reagent: third dynamical system 125 controls the fixator that Single Mechanical arm 81 drives load liquid transfer gun head 41
83 move up, and when kit 120 is left in 41 bottom end of liquid transfer gun head, are provided by location sensitive detection system in Single Mechanical arm 81
Signal, the second dynamical system 123 are run simultaneously with the first dynamical system 121, and control kit 120 is in the second sliding rail 123b and the
It is moved on one sliding rail 121b, the separate storage chamber for filling lytic reagent in reagent storage cabin 30 is then moved into loaded holders 83
The underface of liquid transfer gun head 41, third dynamical system 125 control the liquid transfer gun head 41 that Single Mechanical arm 81 drives loaded holders 83
It moves downward and passes through the pump housing 130 and be automatically drawn into quantitative cleavage reagent, then third dynamical system 125 controls 81 band of Single Mechanical arm
The fixator 83 of dynamic load liquid transfer gun head 41 moves upwards, when kit 120 is left in 41 bottom end of liquid transfer gun head, the second dynamical system
System 123 is run simultaneously with the first dynamical system 121, and control kit 120 is transported on the second sliding rail 123b and the first sliding rail 121b
It is dynamic, then the positioning mark 12 that liquid tank 10 is held in kit 120 is moved to the underface of the fixator 83 of load liquid transfer gun head 41, the
Three dynamical systems 125 control Single Mechanical arm 81 drives the fixator 83 of load liquid transfer gun head 41 to move downward insertion and holds liquid tank 10
Lytic reagent addition is held liquid tank 10 automatically by the pump housing 130 by positioning mark 12；
3. unloading liquid transfer gun head: third dynamical system 125 controls the fixation that Single Mechanical arm 81 drives load liquid transfer gun head 41
Device 83 moves upwards, when kit 120 is left in 41 bottom end of liquid transfer gun head, the second dynamical system 123 and the first dynamical system 121
It runs simultaneously, control kit 120 moves in the second dynamical system 123 and the second sliding rail 123b, then places cabin for first
40 move to the underface of the fixator 83 of load liquid transfer gun head 41, and third dynamical system 125 controls Single Mechanical arm 81 and drives load
The fixator 83 of liquid transfer gun head 41 moves downward and unloads liquid transfer gun head 41 automatically；
4. magnetic: third dynamical system 125 controls Single Mechanical arm 81 and fixator 83 is driven to move upwards, 83 bottom of device to be fixed
When leaving kit 120, the second dynamical system 123 is run simultaneously with the first dynamical system 121 at end, controls kit 120 the
It is moved on two dynamical systems 123 and the second sliding rail 123b, the magnet spare bits 103 for placing magnet 100 is then moved into fixator
83 underface, third dynamical system 125 control Single Mechanical arm 81 and fixator 83 are driven to move downward and load magnet automatically
100, third dynamical system 125 controls Single Mechanical arm 81 and the fixator 83 of load magnet 100 is driven to move upwards, to magnet 100
Bottom end when leaving fixed frame 90, the second dynamical system 123 is run simultaneously with the first dynamical system 121, and control kit 120 exists
It is moved on second dynamical system 123 and the second sliding rail 123b, then magnet magnetic position 101 is moved to the fixation of load magnet 100
The underface of device 83, after the completion of cracking reaction, third dynamical system 125 controls Single Mechanical arm 81 and drives load magnet 100
Fixator 83 moves downward, and moves vertically holding 10 side of liquid tank, to magnetic at the end of, by magnet 100 in magnet magnetic position
101 unloadings；
5. moving waste liquid: third dynamical system 125 controls Single Mechanical arm 81 and fixator 83 is driven to move upwards, device 83 to be fixed
When fixed frame 90 is left in bottom end, the second dynamical system 123 is run simultaneously with the first dynamical system 121, and control kit 120 is the
It is moved on two sliding rail 123b and the first sliding rail 121b, the first placement cabin 40 is being moved into the fixator 83 of load liquid transfer gun head 41 just
Lower section, third dynamical system 125 control Single Mechanical arm 81 and drive fixator 83 to move downward and load liquid transfer gun head 41 automatically, the
Three dynamical systems 125 control Single Mechanical arm 81 drives fixator 83 to move upwards, and leaves kit to 41 bottom end of liquid transfer gun head
120, the second dynamical system 123 is run simultaneously with the first dynamical system 121, and control kit 120 is in the second sliding rail 123b and the
It is moved on one sliding rail 121b, then will hold positioning mark 12 in liquid tank 10 and move to 83 underface of fixator for installing liquid transfer gun head 41 additional,
Third dynamical system 125 controls Single Mechanical arm 81 and drives the fixator 83 for installing liquid transfer gun head 41 additional to move downward and be inserted into positioning mark
12, the fixator 83 of waste liquid sucking installation liquid transfer gun head 41 in liquid tank 10 will be held by the pump housing 130, third dynamical system 125 is controlled
Single Mechanical arm 81 processed drives the fixator 83 for installing liquid transfer gun head 41 additional to move upwards, the second dynamical system 123 and the first dynamical system
System 121 is run simultaneously, and control kit 120 moves on the second sliding rail 123b and the first sliding rail 121b, then in waste liquid cabin 20
Positioning mark 12 moves to the underface for installing the fixator 83 of liquid transfer gun head 41 additional, and third dynamical system 125 controls 81 band of Single Mechanical arm
The dynamic fixator 83 for installing liquid transfer gun head 41 additional is moved downward and is inserted into the positioning mark 12 in waste liquid cabin 20, will be given up by the pump housing 130
Liquid is discharged into waste liquid cabin 20；
6. magnet is moved to spare bits: third dynamical system 125 controls Single Mechanical arm 81 and drives installation liquid transfer gun head 41
Fixator 83 moves upwards, when kit 120 is left in 41 bottom end of liquid transfer gun head, the second dynamical system 123 and the first dynamical system
System 121 is run simultaneously, and control kit 120 moves on the second sliding rail 123b and the first sliding rail 121b, places cabin 40 for first
The underface of the fixator 83 of load liquid transfer gun head 41 is moved to, third dynamical system 125 controls Single Mechanical arm 81 and load is driven to move
The fixator 83 of liquid pipette tips 41 moves downward and unloads liquid transfer gun head 41 automatically, and third dynamical system 125 controls Single Mechanical arm 81
Fixator 83 is driven to move upwards, when kit 120 is left in 83 bottom end of device to be fixed, the second dynamical system 123 and the first power
System 121 is run simultaneously, and control kit 120 moves on the second sliding rail 123b and the first sliding rail 121b, then will place magnetic
The magnet magnetic position 101 of body 100 moves to the underface of fixator 83, and third dynamical system 125 controls Single Mechanical arm 81 and drives admittedly
Determine device 83 and move downward and load automatically magnet 100, third dynamical system 125 controls Single Mechanical arm 81 and drives load magnet 100
Fixator 83 move upwards, when fixed frame 90 is left in 100 bottom end of magnet, the second dynamical system 123 and the first dynamical system
121 run simultaneously, and control kit 120 moves on the second sliding rail 123b and the first sliding rail 121b, and magnet spare bits 103 are moved
To the fixator 83 of load magnet 100, third dynamical system 125 controls Single Mechanical arm 81 and drives load magnet 100
Fixator 83 moves downward and unloads magnet 100 automatically.
Step 5: washing, washing step is similar with cleavage step, also divides 6 steps；It, can depending on washing times are because of sample type
Be 1 time or repeatedly；
1. loading liquid transfer gun head: with the 1 of the 4th step；
2. adding washing reagent: with the 2 of the 4th step, only changing lytic reagent into washing reagent；
3. unloading liquid transfer gun head: with the 3 of the 4th step；
4. magnetic: with the 4 of the 4th step；
5. moving waste liquid: with the 5 of the 4th step；
6. magnet is moved to spare bits: with the 6 of the 4th step；
Step 6: elution, 4 steps of elution step point；
1. loading liquid transfer gun head: with the 1 of the 4th step；
2. adding elution reagent: with the 2 of the 4th step, only changing lytic reagent into elution reagent；
3. unloading liquid transfer gun head: with the 3 of the 4th step；
4. magnetic: with the 4 of the 4th step, to the end of reacting, fixator 83 is placed into cabin 40 first and installs liquid transfer gun head 41 additional,
Final purified product in liquid tank 10 will be held to shift by setting, complete operation.
The above descriptions are merely preferred embodiments of the present invention, is not intended to limit the utility model, for this
For the technical staff in field, various modifications and changes may be made to the present invention.It is all in the spirit and principles of the utility model
Within, any modification, equivalent replacement, improvement and so on should be included within the scope of protection of this utility model.
Claims (10)
1. a kind of separating extraction device, which is characterized in that including pedestal, and support construction on the base is set,
Moving assembly is provided in the support construction, the moving assembly includes fixator, and the fixator includes adapter, described
Adapter is detachably connected with liquid transfer gun head, the channel that the fixator passes through setting in the adapter and the liquid transfer gun head
Connection, the fixator are connect with the pump housing by conduit, suck the liquid transfer gun head or liquid is discharged, on the base also
It is provided with sliding rail, the sliding rail is slidably connected with fixed frame, and kit is provided in the fixed frame, and the kit includes
Hold liquid tank and waste liquid cabin, it is described to hold liquid tank and the useless tank roof is equipped with opening, over said opening equipped with Ka Gai, in institute
It states and is provided with elaxtic seal between opening and card lid, magnet is additionally provided on the fixed frame, the magnet can
It is detachably connected with the adapter.
2. separating extraction device according to claim 1, which is characterized in that the moving assembly further includes Single Mechanical arm,
The Single Mechanical arm is fixedly connected with the fixator.
3. separating extraction device according to claim 1, which is characterized in that further include XYZ dynamical system, the XYZ is dynamic
Force system is used to control the fixed frame respectively in X-direction, the movement of Y direction and the control moving assembly in Z axis
Direction is mobile.
4. separating extraction device according to claim 1, which is characterized in that the kit further include reagent storage cabin,
First places cabin and second places cabin, and the card, which covers to be provided with, holds liquid tank and the waste liquid cabin is two corresponding with described respectively
Through-hole, described hold are provided with dismountable first protective film on liquid tank；
The reagent storage cabin includes multiple reagent storage chambers, and the opening of the waste liquid cabin and the reagent storage chamber is installed with
Second protective film；
The first placement cabin and second placement cabin place liquid transfer gun head respectively and puncture component, described to puncture component and institute
It states fixator to be detachably connected by adapter, be equipped at the top of the first placement cabin and second placement cabin detachable
Third protective film.
5. separating extraction device according to claim 1, which is characterized in that the elaxtic seal is silica gel, rubber
One of.
6. separating extraction device according to claim 4, which is characterized in that be provided on the elaxtic seal and institute
State the corresponding positioning mark of through-hole.
7. separating extraction device according to claim 2, which is characterized in that the two sides in the reagent storage cabin are respectively set
There are two fixed ears.
8. separating extraction device according to claim 4, which is characterized in that the liquid transfer gun head is disposable liquid-transfering gun
Head, the component that punctures is disposable aspiration needle.
9. separating extraction device according to claim 1, which is characterized in that the magnet is magnet or electromagnet.
10. a kind of separation and Extraction system, which is characterized in that including anticollision inductor and position sensor and such as claim 1-9
Described in any item separating extraction devices, the anticollision inductor and the position sensor are arranged on the moving assembly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821554891.5U CN209322849U (en) | 2018-09-21 | 2018-09-21 | A kind of separating extraction device and separation and Extraction system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821554891.5U CN209322849U (en) | 2018-09-21 | 2018-09-21 | A kind of separating extraction device and separation and Extraction system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209322849U true CN209322849U (en) | 2019-08-30 |
Family
ID=67707258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821554891.5U Active CN209322849U (en) | 2018-09-21 | 2018-09-21 | A kind of separating extraction device and separation and Extraction system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209322849U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108977344A (en) * | 2018-09-21 | 2018-12-11 | 西安佰奥莱博生物科技有限公司 | A kind of separating extraction device and separating and extracting process |
| CN114110351A (en) * | 2021-12-06 | 2022-03-01 | 广东润鹏生物技术有限公司 | Anti-collision mechanism, biological PCR detection system and anti-collision control method |
-
2018
- 2018-09-21 CN CN201821554891.5U patent/CN209322849U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108977344A (en) * | 2018-09-21 | 2018-12-11 | 西安佰奥莱博生物科技有限公司 | A kind of separating extraction device and separating and extracting process |
| CN114110351A (en) * | 2021-12-06 | 2022-03-01 | 广东润鹏生物技术有限公司 | Anti-collision mechanism, biological PCR detection system and anti-collision control method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4230816B2 (en) | Plate that automatically stores part of the sample | |
| US9073052B2 (en) | Lab members and liquid handling systems and methods including same | |
| CN209322849U (en) | A kind of separating extraction device and separation and Extraction system | |
| BRPI0717331B1 (en) | DEVICE FOR AUTOMATIC SETTING OF THE BACTERIAL INOCULUS LEVEL OF A SAMPLE | |
| CN107356587B (en) | Light-activated chemiluminescence instant detection system | |
| JP2015508177A (en) | System, apparatus and device for preparing cells | |
| WO1997044671A1 (en) | Method and apparatus for controlling magnetic particles by pipetting machine | |
| CN108977344A (en) | A kind of separating extraction device and separating and extracting process | |
| JP7057813B2 (en) | Pipetting unit and pipetting method for closed liquid containers | |
| CN113125787A (en) | Full-automatic chemiluminescence immunoassay analyzer | |
| CN106018352B (en) | Photo-electric Biochemical Analyzer and its analysis method | |
| EP1615037A1 (en) | An apparatus for liquid handling with multiple transfer tools | |
| CN115248328A (en) | POCT blood cell analyzer and using method thereof | |
| CN205879790U (en) | Biochemical analysis appearance of photoelectric type | |
| CN114323783B (en) | Sampling method, sampling assembly and sample analyzer | |
| CN215866723U (en) | POCT blood cell analyzer | |
| CN215180255U (en) | POCT blood cell analyzer | |
| CN216525868U (en) | POCT blood cell analyzer | |
| CN216387080U (en) | POCT blood cell analyzer and kit | |
| US20220395784A1 (en) | Mixing liquids using an automated liquid handling system | |
| CN113686760B (en) | Kit and POCT blood cell analyzer | |
| CN220239554U (en) | Integrated automatic cleaning reaction device | |
| CN216525869U (en) | POCT blood cell analyzer, detection seat | |
| CN216236988U (en) | High-throughput automatic protein transfection platform | |
| CN214794844U (en) | Full-automatic chemiluminescence immunoassay analyzer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |