CN209302615U - Leakproof evenly mixing device for in-vitro diagnosis equipment - Google Patents
Leakproof evenly mixing device for in-vitro diagnosis equipment Download PDFInfo
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- CN209302615U CN209302615U CN201822054211.XU CN201822054211U CN209302615U CN 209302615 U CN209302615 U CN 209302615U CN 201822054211 U CN201822054211 U CN 201822054211U CN 209302615 U CN209302615 U CN 209302615U
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- leakproof
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- mixing device
- vitro diagnosis
- evenly mixing
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Abstract
The utility model discloses a kind of leakproof evenly mixing devices for in-vitro diagnosis equipment, including the leakage-proof socket being arranged in mounting base, the top edge of leakage-proof socket expands outwardly to form collection port, the first eccentric mixing head by power mechanism driving is provided in leakage-proof socket, the first eccentric head that mixes includes the shielding cap for clamping the locating slot of reaction cup He Open Side Down, positions and offers fluid hole in groove groove wall；The driving gear transmission connection of the through-hole and power mechanism in leakproof groove bottom wall is pierced by under the first axial rotary being connected on shielding cap, the edge of through-hole is vertically bent to form the leakproof boss for being cylindrical in shape structure upwards, extends upwardly in the shielding cap at the top of leakproof boss；The eccentric spacing d of locating slot central axes and first rotary shaft central axes is 0.5-3.0mm.The utility model structure is simple, and mixing intensity is adjustable and mixed effect is good, collects the liquid of spluttering in blending process by leakage-proof socket, prevents liquid from flowing out or splashing on machine, protects machine.
Description
Technical field
The utility model relates to vitro detection equipment, mix dress more particularly, to a kind of leakproof for in-vitro diagnosis equipment
It sets.
Background technique
Existing in-vitro diagnosis equipment (such as chemical illumination immunity analysis instrument, Biochemical Analyzer and nucleic acid instrument) utilizes chemistry more
Or instruction system of the bio-luminescence system as antigen-antibody reaction, so as to quantitative detection antigen or antibody.Isolating and purifying sample
The specific antibody or receptor (i.e. target body) in magnetic bead absorption sample are usually utilized when product, and waste liquid in reaction cup, note is then sucked out
Liquid cleaning, removes the not substance in conjunction with antigen or antibody and the other interfering substances being supported on magnetic bead in reaction solution.
It follows that magnetic bead cleaning is to influence the key factor of testing result.Existing magnetic bead cleaning device is by hair washing component and reaction
Cup rotary disk assembly composition draws the waste liquid or injection cleaning solution of reaction cup, evenly mixing device pair by hair washing component entirety ascending, descending
Magnetic bead in rotating disk in reaction cup is mixed well with cleaning solution, to ensure cleaning effect.Application for a patent for invention
CN103599898A discloses a kind of Full-automatic chemiluminescence immunoassay analysis meter magnetic bead cleaning device, including is driven by rotating electric machine
Rotating disk, evenly mixing device and magnetic iron absorption device, evenly mixing device is by mixing eccentric friction pulley (being driven by motor) and holding out against machine
Structure is constituted, and friction pulley drives reaction cup rotation, and when friction pulley long axis is close to reaction cup, reaction cup is tilted to jacking mechanism, top
The spring of tight mechanism is in compression stress, when friction pulley short axle is close to reaction cup, the restoring force driving a reaction cup of spring
It is tilted to wheel side is mixed, and so on, it is ensured that the magnetic bead in reaction cup is mixed well with cleaning solution.The liquid in blending process
It is easy to splash, causes to pollute instrument while cross contamination；It cannot be adjusted using the blending manner of eccentric friction pulley extruding reaction cup
Whole mixing intensity.
Summary of the invention
The utility model aim is to provide a kind of leakproof evenly mixing device for in-vitro diagnosis equipment, not only ensures to mix
Effect, moreover it is possible to avoid in blending process completely in reaction cup on liquid splash to machine.
To achieve the above object, the utility model takes following technical proposals:
Leakproof evenly mixing device described in the utility model for in-vitro diagnosis equipment, it is anti-in mounting base including being arranged in
Bakie, the top edge of the leakage-proof socket expand outwardly to form collection port, are provided in leakage-proof socket by the first of power mechanism driving
Bias mixes head, and the described first eccentric head that mixes includes the shielding cap for clamping the locating slot of reaction cup He Open Side Down, institute
It states and offers fluid hole in positioning groove groove wall；It is pierced by leakproof groove bottom wall under the first axial rotary being connected on the shielding cap
Through-hole and power mechanism driving gear be sequentially connected, the edge of the through-hole is vertically bent to form upwards is cylindrical in shape structure
Leakproof boss extends upwardly in the shielding cap at the top of the leakproof boss；The locating slot central axes and described first
The eccentric spacing d of rotary shaft central axes is 0.5-3.0mm.
The described first eccentric shielding cap for mixing head is cylindrical-shaped structure, ellipsoidal structures, polygon prism shape structure or upper small
Big truncated cone structure down.
The described first eccentric shielding cap for mixing head is up-small and down-big truncated cone structure.
The power mechanism includes the vertical plate being vertically arranged in the mounting base, is provided with sliding rail and liter on the vertical plate
Motor drops, and the lifting motor drives rotary components to slide up and down along the sliding rail by transmission, and the rotary components include
The mounting rack being slidably arranged on sliding rail, the mounting rack bottom are provided with rotating electric machine, are sleeved on the rotating electric machine output
The driving gear on axis is rotatably arranged in the pinion stand at the top of mounting rack, is provided in the pinion stand and driving gear
First driven gear of engagement, the bottom of first rotary shaft, which is worn, to be connected in first driven gear.
It is set with first axle bearing sleeve in first rotary shaft of two sides above and below first driven gear, described
One bearing holder (housing, cover) is rotatably assorted with the pinion stand.
The second driven gear being meshed with driving gear, institute are provided in the pinion stand on the right side of the driving gear
State the second rotary shaft for being fixed with and upwardly extending in the second driven gear, the top in second rotary shaft be fixed with it is described
First eccentric identical second bias of header structure that mixes mixes head.
It is set with second bearing set in second rotary shaft of two sides above and below second driven gear, described
Two bearing holder (housing, cover)s are rotatably assorted with the pinion stand.
It is provided with the bracket of L-shaped structure in the mounting base, is arranged at intervals on the cross bar of the bracket and described
First reaction cup limit hole of one concentric rotation axis line and the second reaction cup limit hole with the second concentric rotation axis line, institute
State the first reaction cup limit hole and the first eccentric head that mixes be correspondingly arranged up and down, the second reaction cup limit hole with it is described
The second eccentric head that mixes is correspondingly arranged up and down.
It is provided with sensing chip on the mounting rack, the position sensing for detecting the sensing chip signal is provided on the vertical plate
Device.
Leak-resistant sensor is provided on the side wall of the leakage-proof socket.
It is simple that the utility model has the advantage of structures, and mixing intensity is adjustable and mixed effect is good, passes through in blending process
Leakage-proof socket collects the liquid of spluttering, prevents liquid from flowing out or splashing on machine.The advantages of the utility model be embodied in
Lower several points: it is flowed into locating slot when (1) mixing from the liquid that reaction cup sputters along reaction cup wall of cup, then again by locating slot
Fluid hole flow out and fall on shielding cap, and slide from the shielding cap of truncated cone structure to leakproof trench bottom, prevent liquid
It is flowed out out of leakage-proof socket；Fluid hole can guarantee that liquid is flowed out out of locating slot in time simultaneously, avoid liquid crystalization in locating slot
And influence mixed effect；(2), mixing state or the first eccentric shielding cap for mixing head and leakage-proof socket all exist when non-mixing state
It is overlapped overlap joint, prevents liquid from flowing out out of leakage-proof socket；When the coconnected drain pipe of leakage-proof socket blocks, liquid level in leakage-proof socket
When rising at leak-resistant sensor position, leak-resistant sensor triggering issues signal, reminds staff's maintenance down, protects machine
Device；(3), lifting motor adjustable first is eccentric mixes grease head highness adjustment, and the revolving speed speed of rotating electric machine determines liquid in reaction cup
Body mixes intensity, by adjusting first it is eccentric mix grease head highness and revolving speed guarantees liquid blending effect, simultaneously because locating slot and
The setting of first rotating shaft eccentric, the first eccentric mix while head revolves with the first rotary shaft make reaction cup shake, similarly
Second eccentric mix also can guarantee that reaction cup is shaken while head revolves, and mix well the liquid in reaction cup, and then guarantee
Fully reacting, it is ensured that the reliability of testing result；(4), the second eccentric head that mixes is used to mix small anti-of reaction reagent additive amount
Cup is answered, liquid splash can be avoided completely since mixing amount is small；The second eccentric head that mixes is worked at the same time with the first eccentric head that mixes, and is mentioned
High blending efficiency.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model.
Fig. 2 is the structural schematic diagram (omitting mounting base and leakage-proof socket) of the utility model.
Fig. 3 is the installation status diagram of the utility model.
Specific embodiment
As shown in Figure 1-3, the leakproof evenly mixing device described in the utility model for in-vitro diagnosis equipment, including setting exist
Leakage-proof socket 2.1 on 1 cylinder of mounting base, 1.1 side wall, leak-resistant sensor 2.3 is provided on 2.1 side wall of leakage-proof socket, and leakproof passes
The signal output end of sensor 2.3 is electrically connected with the signal output end of controller, when the drain line of leakage-proof socket 2.1 blocks
When, liquid level rises at leak-resistant sensor position in leakage-proof socket 2.1, and leak-resistant sensor triggers to controller and issues signal, control
Device issues complete machine halt instruction, protects machine；The top edge of the leakage-proof socket 2.1 expands outwardly to form collection port, leakage-proof socket 2.1
It is inside provided with the first eccentric mixing head 3 by power mechanism driving, the described first eccentric head 3 that mixes includes described anti-for clamping
The locating slot 3.1 of cup and the shielding cap 3.2 that Open Side Down are answered, is opened up on the described first eccentric 3.1 cell wall of locating slot for mixing head 3
Have fluid hole 3.3, it is ensured that liquid is drained into time in leakage-proof socket 2.1 in locating slot 3.1, prevent liquid crystalization in locating slot 3.1 and
Mixed effect is influenced, shielding cap 3.2 is up-small and down-big truncated cone structure, is slid convenient for liquid to leakage-proof socket 2.1, is connected
The first rotary shaft 3.4 on the shielding cap 3.2 is pierced by downwards the active of through-hole and power mechanism on 2.1 bottom wall of leakage-proof socket
Gear 4.1 is sequentially connected, and the top of shielding cap 3.2 is provided with locking cap 3.5, and locking cap 3.5 is sleeved in the first rotary shaft 3.4
And be fixedly connected with by bolt 3.6 with the first rotary shaft 3.4, the edge of the through-hole is vertically bent to form upwards is cylindrical in shape structure
Leakproof boss 2.2, the top of the leakproof boss 2.2 extend upwardly in the shielding cap 3.2, mix state or non-mixing shape
The first eccentric shielding cap 3.2 for mixing head all exists with leakage-proof socket 2.1 when state is overlapped overlap joint, prevents liquid out of leakage-proof socket 2.1
Outflow；The eccentric spacing of 3.1 central axes of locating slot and 3.4 central axes of the first rotary shaft is 0.5-3.0mm, is guaranteed anti-
It answers cup to generate shaking while rotating with the first rotary shaft 3.4, guarantees mixed effect.
As shown in Figure 1,3, the power mechanism includes the vertical plate 4.2 being vertically arranged in the mounting base 1, the vertical plate
Sliding rail 4.3 and lifting motor 4.4 are provided on 4.2, the lifting motor 4.4 drives rotary components along the cunning by transmission
Rail 4.3 slides up and down, and the rotary components include the mounting rack 4.5 being slidably arranged on sliding rail 4.3,4.5 bottom of mounting rack
Portion is provided with rotating electric machine 4.6, and the motor shaft of rotating electric machine 4.6 is connected with the output shaft extended straight up by shaft joint
4.13, driving gear 4.1 is sleeved on output shaft 4.13 and is rotatably arranged in the pinion stand 4.7 at 4.5 top of mounting rack, described
The first driven gear 4.8 engaged with driving gear 4.1 is provided in pinion stand 4.7, the bottom of first rotary shaft 3.4 is worn
First rotary shaft if being connected in first driven gear 4.8, positioned at about 4.8 two sides of the first driven gear
First axle bearing sleeve 4.9 is set on 3.4, the first axle bearing sleeve 4.9 is rotatably assorted with the pinion stand 4.7；The mounting rack
It is provided with sensing chip 7.1 on 4.5, the position sensor 7.2 for detecting 7.1 signal of sensing chip is provided on the vertical plate 4.2,
The signal of sensing chip 7.1 is detected by position sensor 7.2, and then accurately controls the height of rotary components, is rotated by adjusting
The revolving speed adjustment of motor 4.6 mixes intensity, guarantees mixed effect.
As shown in Figure 1-3, being provided in the pinion stand 4.7 on 4.1 right side of driving gear to improve blending efficiency
The second driven gear 4.10 being meshed with driving gear 4.1, described in about 4.10 two sides of the second driven gear
Second bearing set 4.12 is set in second rotary shaft 4.11, the second bearing set 4.12 is matched with the pinion stand 4.7 rotation
It closes, is fixed with the second rotary shaft 4.11 upwardly extended in second driven gear 4.10, in second rotary shaft 4.11
Top be fixed with second it is eccentric mix head 5, the second eccentric eccentric head 3 that mixes of the structure first for mixing head 5 is identical, second
Bias mixes head 5 and can mix to the reaction cup after addition reaction reagent, it is ensured that fully reacting is further ensured that pattern detection
As a result reliability.When work, rotating electric machine 4.6 drives the first, second driven gear 4.10 to turn simultaneously by driving gear 4.1
It is dynamic, and then drive the first eccentric mixing head 3 and the second eccentric head 5 that mixes to rotate simultaneously, and then realize the mixing of two reaction cups,
Improve blending efficiency；Lifting motor 4.4 drives rotary components to rise or fall, and then adjusts the first eccentric mixing head 3 simultaneously
With the second eccentric height for mixing head 5.
As shown in Figure 1,3, it is the stability for being further ensured that reaction cup, is provided with L-shaped structure in the mounting base 1
Bracket 6.1, is arranged at intervals on the cross bar of the bracket 6.1 and the first reaction cup of 3.4 coaxial line of the first rotary shaft limits
Position hole 6.2 and the second reaction cup limit hole 6.3 with 4.11 coaxial line of the second rotary shaft, the first reaction cup limit hole
6.2 are correspondingly arranged with the described first eccentric about 3 head that mixes, and the second reaction cup limit hole 6.3 is eccentric mixed with described second
Even about 5 head is correspondingly arranged, and the first reaction cup limit hole 6.2 and the second reaction cup limit hole 6.3 are located in reaction cup rotating disk
Side, has position-limiting action, and the Oscillation Amplitude of limited reactions cup reduces the probability of liquid spluttering.
The eccentric mixing head of the first of the utility model evenly mixing device and the second eccentric head that mixes are located at reaction cup rotation
Below the inner ring reaction cup aperture and outer ring reaction cup aperture of disk.When work, reaction cup rotating disk rotates the reaction cup for mixing needs
It takes to and mixes position, the bottom of reaction cup is installed in the first eccentric mixing head 3 and/or the second eccentric mixing head 5, passes through lifting
The adjustment of motor 4.4 first is eccentric to mix head 3 and the second eccentric height for mixing head 5, and rotating electric machine 4.6 passes through driving gear 4.1
It drives the first driven gear 4.8 and the second driven gear 4.10 while rotating, and then drive the first eccentric mixing head 3 and second partially
The heart mixes head 5 and rotates simultaneously to liquid blending in reaction cup.Extension liquid and first after injection needle is added dropwise when cleaning is eccentric mixed
The liquid sputtered in even 3 rotation process of head by reaction cup rim of a cup enters directly into 2.1 bottom of leakage-proof socket by collection port, or along
Reaction cup cup body is flow in locating slot 3.1, is then fallen on the shielding cap 3.2 in truncated cone structure through fluid hole 3.3, by hiding
Gear cap 3.2 slides to leakage-proof socket 2.1, prevents liquid from flowing on machine, protects machine environment.
Claims (10)
1. a kind of leakproof evenly mixing device for in-vitro diagnosis equipment, it is characterised in that: anti-including what is be arranged on mounting base (1)
The top edge of bakie (2.1), the leakage-proof socket (2.1) expands outwardly to form collection port, is provided in leakage-proof socket (2.1) by power
The first of mechanism driving is eccentric to mix head (3), and the described first eccentric mix head (3) include the locating slot for clamping reaction cup
(3.1) and the shielding cap (3.2) that Open Side Down fluid hole (3.3), are offered on locating slot (3.1) cell wall；It is connected in institute
State the master of through-hole and power mechanism that the first rotary shaft (3.4) on shielding cap (3.2) is pierced by downwards on leakage-proof socket (2.1) bottom wall
Moving gear (4.1) transmission connection, the edge of the through-hole are vertically bent to form the leakproof boss (2.2) for being cylindrical in shape structure upwards,
It is extended upwardly at the top of the leakproof boss (2.2) in the shielding cap (3.2)；Locating slot (3.1) central axes and institute
The eccentric spacing d for stating the first rotary shaft (3.4) central axes is 0.5-3.0mm.
2. the leakproof evenly mixing device according to claim 1 for in-vitro diagnosis equipment, it is characterised in that: described first partially
The shielding cap (3.2) that the heart mixes head (3) is cylindrical-shaped structure, ellipsoidal structures, polygon prism shape structure or up-small and down-big circular cone
Platform shape structure.
3. the leakproof evenly mixing device according to claim 2 for in-vitro diagnosis equipment, it is characterised in that: described first partially
The shielding cap (3.2) that the heart mixes head (3) is up-small and down-big truncated cone structure.
4. the leakproof evenly mixing device according to claim 2 for in-vitro diagnosis equipment, it is characterised in that: the engine
Structure includes the vertical plate (4.2) being vertically arranged on the mounting base (1), and sliding rail (4.3) is provided on the vertical plate (4.2) and is risen
It drops motor (4.4), the lifting motor (4.4) drives rotary components to slide up and down along the sliding rail (4.3) by transmission, institute
Stating rotary components includes the mounting rack (4.5) being slidably arranged on sliding rail (4.3), and mounting rack (4.5) bottom is provided with rotation
Rotating motor (4.6), the driving gear (4.1) being sleeved on the rotating electric machine (4.6) output shaft are rotatably arranged on installation
In pinion stand (4.7) at the top of frame (4.5), be provided in the pinion stand (4.7) engaged with driving gear (4.1) first from
Moving gear (4.8), the bottom of first rotary shaft (3.4), which is worn, to be connected in first driven gear (4.8).
5. the leakproof evenly mixing device according to claim 4 for in-vitro diagnosis equipment, it is characterised in that: be located at described the
One driven gear (4.8) is set with first axle bearing sleeve (4.9) on first rotary shaft (3.4) of two sides up and down, and described first
Bearing holder (housing, cover) (4.9) is rotatably assorted with the pinion stand (4.7).
6. the leakproof evenly mixing device according to claim 4 for in-vitro diagnosis equipment, it is characterised in that: be located at the master
The second driven gear being meshed with driving gear (4.1) is provided in pinion stand (4.7) on the right side of moving gear (4.1)
(4.10), the second rotary shaft (4.11) upwardly extended, second rotation are fixed in second driven gear (4.10)
Top on axis (4.11) is fixed with the second eccentric mixing head (5) identical with first bias mixing head (3) structure.
7. the leakproof evenly mixing device according to claim 6 for in-vitro diagnosis equipment, it is characterised in that: be located at described the
Two driven gears (4.10) are set with second bearing set (4.12) on second rotary shaft (4.11) of two sides up and down, and described
Two bearing holder (housing, cover)s (4.12) are rotatably assorted with the pinion stand (4.7).
8. the leakproof evenly mixing device according to claim 6 for in-vitro diagnosis equipment, it is characterised in that: the mounting base
(1) it is provided with the bracket (6.1) of L-shaped structure on, is arranged at intervals on the cross bar of the bracket (6.1) and first rotation
It the first reaction cup limit hole (6.2) of axis (3.4) coaxial line and is reacted with the second of the second rotary shaft (4.11) coaxial line
Cup limit hole (6.3), the first reaction cup limit hole (6.2) are correspondingly arranged with the described first eccentric mix head (3) or more, institute
The second reaction cup limit hole (6.3) is stated to be correspondingly arranged with the described second eccentric mix head (5) or more.
9. the leakproof evenly mixing device according to claim 4 for in-vitro diagnosis equipment, it is characterised in that: the mounting rack
(4.5) it is provided on sensing chip (7.1), the position biography for detecting sensing chip (7.1) signal is provided on the vertical plate (4.2)
Sensor (7.2).
10. the leakproof evenly mixing device according to claim 1 for in-vitro diagnosis equipment, it is characterised in that: the leakproof
Leak-resistant sensor (2.3) are provided on the side wall of slot (2.1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822054211.XU CN209302615U (en) | 2018-12-08 | 2018-12-08 | Leakproof evenly mixing device for in-vitro diagnosis equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822054211.XU CN209302615U (en) | 2018-12-08 | 2018-12-08 | Leakproof evenly mixing device for in-vitro diagnosis equipment |
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| Publication Number | Publication Date |
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| CN209302615U true CN209302615U (en) | 2019-08-27 |
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ID=67676080
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201822054211.XU Active CN209302615U (en) | 2018-12-08 | 2018-12-08 | Leakproof evenly mixing device for in-vitro diagnosis equipment |
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| CN (1) | CN209302615U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109382025A (en) * | 2018-12-08 | 2019-02-26 | 安图实验仪器(郑州)有限公司 | Leakproof evenly mixing device for in-vitro diagnosis equipment |
-
2018
- 2018-12-08 CN CN201822054211.XU patent/CN209302615U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109382025A (en) * | 2018-12-08 | 2019-02-26 | 安图实验仪器(郑州)有限公司 | Leakproof evenly mixing device for in-vitro diagnosis equipment |
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