CN209292355U - A kind of bioreactor sampler - Google Patents
A kind of bioreactor sampler Download PDFInfo
- Publication number
- CN209292355U CN209292355U CN201821995618.6U CN201821995618U CN209292355U CN 209292355 U CN209292355 U CN 209292355U CN 201821995618 U CN201821995618 U CN 201821995618U CN 209292355 U CN209292355 U CN 209292355U
- Authority
- CN
- China
- Prior art keywords
- liquid
- fixedly connected
- sampler
- flowing tube
- shell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000007788 liquid Substances 0.000 claims abstract description 74
- 238000000926 separation method Methods 0.000 claims abstract description 14
- 239000004973 liquid crystal related substance Substances 0.000 claims abstract description 8
- 239000010410 layer Substances 0.000 claims abstract description 6
- 230000005540 biological transmission Effects 0.000 claims abstract description 5
- 239000011229 interlayer Substances 0.000 claims abstract description 4
- 239000002184 metal Substances 0.000 claims description 3
- 230000003014 reinforcing effect Effects 0.000 claims description 3
- 239000005341 toughened glass Substances 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 2
- 238000009830 intercalation Methods 0.000 description 2
- 230000002687 intercalation Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 210000004102 animal cell Anatomy 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a kind of bioreactor samplers, including sampler shell and liquid separation end, sampler shell upper end is fixedly connected with metering pump, the sampler housing forward end is fixedly connected with observation window and liquid crystal display, upper end is fixedly connected with liquid feeding end on the left of the sampler shell, lower end is fixedly connected with control assembly on the left of the sampler shell, outlet end is fixedly connected in the middle part of sampler shell lower end, liquid separation end inner cavity is provided with clamping groove, the liquid feeding end left end is fixedly connected with liquid flowing tube, the liquid flowing tube end is fixedly connected with liquid taking head, the liquid flowing tube is double-layer structure, transmission line is equipped in its interlayer, temperature sensor and liquid level sensor are equipped on the outside of the liquid flowing tube, the sampler can obtain the sample liquid of different depth in reactor.
Description
Technical field
The utility model relates to Bioexperiment apparatus field, specially a kind of bioreactor sampler.
Background technique
When animal cells in vitro culture, bioreactor is the key equipment of entire incubation, provides one for cell
A suitable growing environment, biological tissue's product needed for being allowed to fast breeding and being formed.Since zooblast is in its form knot
Structure, cultural method and required mechanical environment etc. are different from microbial cell, thus traditional microorganism reactor
Obviously it has not been suitable for the needs of zooblast large-scale culture, especially organizational project, has promoted grinding for new-type bioreactor
Study carefully and develop, the liquid outlet of existing bioreactor is often arranged in bottom, simultaneous reactions device sampler shell also compared with
It is deep, it is difficult to obtain the sample of different depth, for this purpose, we have proposed a kind of bioreactor samplers, on solving
State problem.
Utility model content
The purpose of this utility model is to provide a kind of bioreactor samplers, to solve in above-mentioned background technique
The problem of proposition.
To achieve the above object, the utility model provides the following technical solutions: a kind of bioreactor sampler, packet
Sampler shell and liquid separation end are included, sampler shell upper end is fixedly connected with metering pump, and the sampler housing forward end is solid
Surely it is connected with observation window and liquid crystal display, handle is fixedly connected on the right side of the sampler shell, the sampler shell is left
Side upper end is fixedly connected with liquid feeding end, and lower end is fixedly connected with control assembly, the control assembly on the left of the sampler shell
On be fixedly connected with adjusting knob and switch, outlet end is fixedly connected in the middle part of sampler shell lower end, in the outlet end
Section is fixedly connected with solenoid valve, and the outlet end end is fixedly connected with clamping ring, and liquid separation end inner cavity is provided with clamping groove, institute
It states liquid separation end lower end and is connected through a screw thread part and be threaded with taper liquid-dividing head and common liqiud outlet head, the liquid feeding end left end is fixed
It is connected with liquid flowing tube, the liquid flowing tube end is fixedly connected with liquid taking head, and the liquid flowing tube is double-layer structure, is equipped in interlayer
Transmission line, the liquid flowing tube outside are equipped with temperature sensor and liquid level sensor.
Preferably, central processing unit, the metering pump, control assembly, temperature sensor are equipped in the sampler shell
With liquid level sensor with central processing unit electrical series.
Preferably, the observation window is made of tempered glass.
Preferably, the liquid flowing tube is made of medical grade rubber.
Preferably, the threaded connector is made of flexiplast, and metal reinforcing ring is equipped in the threaded connector.
Compared with prior art, the utility model has the beneficial effects that this kind of bioreactor sampler, by setting
The structure for setting taper liquid-dividing head and common liqiud outlet head has reached the effect that can satisfy the different demands for collecting metering and collection device
Fruit improves the wide usage of the sampler；By the way that the structure of temperature sensor and liquid level sensor is arranged, having reached can be accurate
The effect of positioning sampling layer depth.
Detailed description of the invention
FIG. 1 is a schematic structural view of the utility model；
Fig. 2 is the cross-sectional view at the utility model liquid separation end；
Fig. 3 is the partial sectional view of the utility model liquid flowing tube.
In figure: 1 sampler shell, 11 observation windows, 12 liquid crystal displays, 13 metering pumps, 14 outlet ends, 141 solenoid valves,
142 clamping rings, 15 handles, 16 liquid feeding ends, 17 control assemblies, 18 adjusting knobs, 19 switches, 2 liquid separation ends, 21 taper liquid-dividing heads, 22
Common liqiud outlet head, 3 liquid flowing tubes, 31 liquid taking heads, 32 temperature sensors, 33 liquid level sensors, 34 transmission lines.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Fig. 1-3 is please referred to, the utility model provides a kind of technical solution: a kind of bioreactor sampler, including
Sampler shell 1 and liquid separation end 2,1 upper end of sampler shell are fixedly connected with metering pump 13, before the sampler shell 1
End is fixedly connected with observation window 11 and liquid crystal display 12, the model SM.04VL16/LI of the liquid crystal display 12, observation
Window 11 can real-time monitoring pump out the color and quality of sample, the observation window 11 is made of tempered glass, has preferable resistance to
Corrosivity and longer service life, handle 15 is fixedly connected on the right side of the sampler shell 1, and the handle 15 is equipped with anti-
Sliding lines, can increase degree of stability when gripping, the 1 left side upper end of sampler shell is fixedly connected with liquid feeding end 16, institute
It states 1 left side lower end of sampler shell and is fixedly connected with control assembly 17, be fixedly connected with adjusting knob 18 in the control assembly 17
With switch 19, adjusting knob 18 is used to adjust the flow of metering pump 13, the model GM-0.33A of the metering pump 13, and switch 19 is used
It opens and closes metering pump 13, is fixedly connected with outlet end 14 in the middle part of 1 lower end of sampler shell, 14 middle section of outlet end is fixed
It is connected with solenoid valve 141, the model 4v210-08 of the solenoid valve 141,4 end of outlet end is fixedly connected with clamping
Ring 142,2 inner cavity of liquid separation end are provided with clamping groove 23, and 142 activity of clamping ring is connected in clamping groove 23, the liquid separation
It holds 2 lower ends to be connected through a screw thread part 25 and is threaded with taper liquid-dividing head 21 and common liqiud outlet head 22, the common liqiud outlet head 22
Lower end is equipped with half arc incision, can reduce the sprinkling of sample liquid, the upper surface of outlet end 4 end and threaded connector 25
Tangent, the threaded connector 25 is made of flexiplast, and metal reinforcing ring 24 is equipped in the threaded connector 25, can
Increase airtightness, sample liquid is avoided to leak, 16 left end of liquid feeding end is fixedly connected with liquid flowing tube 3, and the liquid flowing tube 3 is by medical
Rubber is made, and 3 end of liquid flowing tube is fixedly connected with liquid taking head 31, and the liquid taking head 31 is made of medical plastic, described to take
Liquid pipe 3 is double-layer structure, and transmission line 34 is equipped in interlayer, and temperature sensor 32 is equipped on the outside of the liquid flowing tube 3 and liquid level passes
Sensor 33, the 32 model CWDZ11 of temperature sensor, the model CYW11 of the liquid level sensor 33, the temperature pass
Sensor 32 and liquid level sensor 33 are separately positioned on the two sides of liquid flowing tube 3 and equidistant interval is arranged, 32 He of temperature sensor
It is divided into 0.5cm between liquid level sensor 33, is equipped with central processing unit, the type of the central processing unit in the sampler shell 1
Number be 6ES7-312, the LCD panel 12, metering pump 13, control assembly 17, temperature sensor 32 and liquid level sensor 33
With central processing unit electrical series, when below 3 intercalation reaction device liquid level of liquid flowing tube, temperature sensor 32 and liquid level sensor
33 can convert electric signal transmission into central processing unit for the physical signal detected, identification and place by central processing unit
It, can be by the physical message real-time display detected on liquid crystal display 12 after reason.
Working principle:
Firstly, bioreactor upper cover is opened, it will be in the liquid level in 3 intercalation reaction device of liquid flowing tube；
Then, according to the difference of sampling container, the position at liquid separation end 2 is adjusted, suitable liqiud outlet head and outlet end 14 is right
Together, and using adjusting knob 18 flow velocity of metering pump 13 is adjusted；
Finally, determining the depth of liquid taking head 31 according to the data on liquid crystal display 12, then metering is opened by switch 19
Pump 13, to obtain the sample liquid of differential responses layer depth.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (5)
1. a kind of bioreactor sampler, including sampler shell (1) and liquid separation end (2), it is characterised in that: described to take
Sample device shell (1) upper end is fixedly connected with metering pump (13), and sampler shell (1) front end is fixedly connected with observation window (11)
With liquid crystal display (12), sampler shell (1) right side is fixedly connected with handle (15), and the sampler shell (1) is left
Side upper end is fixedly connected with liquid feeding end (16), and lower end is fixedly connected with control assembly (17), institute on the left of the sampler shell (1)
It states and is fixedly connected with adjusting knob (18) and switch (19) on control assembly (17), it is fixed in the middle part of sampler shell (1) lower end
It is connected with outlet end (14), outlet end (14) middle section is fixedly connected with solenoid valve (141), and outlet end (14) end is solid
Surely it is connected with clamping ring (142), liquid separation end (2) inner cavity is provided with clamping groove (23), and liquid separation end (2) lower end passes through screw thread
Connector (25) is threaded with taper liquid-dividing head (21) and common liqiud outlet head (22), and liquid feeding end (16) left end is fixedly connected
Having liquid flowing tube (3), liquid flowing tube (3) end is fixedly connected with liquid taking head (31), and the liquid flowing tube (3) is double-layer structure,
Transmission line (34) are equipped in interlayer, temperature sensor (32) and liquid level sensor (33) are equipped on the outside of the liquid flowing tube (3).
2. a kind of bioreactor sampler according to claim 1, it is characterised in that: the sampler shell
(1) central processing unit, the metering pump (13), control assembly (17), temperature sensor (32) and liquid level sensor are equipped in
(33) with central processing unit electrical series.
3. a kind of bioreactor sampler according to claim 1, it is characterised in that: the observation window (11) by
Tempered glass is made.
4. a kind of bioreactor sampler according to claim 1, it is characterised in that: the liquid flowing tube (3) by
Medical grade rubber is made.
5. a kind of bioreactor sampler according to claim 1, it is characterised in that: the threaded connector
(25) it is made of flexiplast, is equipped with metal reinforcing ring (24) in the threaded connector (25).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821995618.6U CN209292355U (en) | 2018-11-30 | 2018-11-30 | A kind of bioreactor sampler |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821995618.6U CN209292355U (en) | 2018-11-30 | 2018-11-30 | A kind of bioreactor sampler |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209292355U true CN209292355U (en) | 2019-08-23 |
Family
ID=67656835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821995618.6U Expired - Fee Related CN209292355U (en) | 2018-11-30 | 2018-11-30 | A kind of bioreactor sampler |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209292355U (en) |
-
2018
- 2018-11-30 CN CN201821995618.6U patent/CN209292355U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190823 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |