CN209215736U - A kind of lenticule heeling-in collimator - Google Patents
A kind of lenticule heeling-in collimator Download PDFInfo
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- CN209215736U CN209215736U CN201920028050.9U CN201920028050U CN209215736U CN 209215736 U CN209215736 U CN 209215736U CN 201920028050 U CN201920028050 U CN 201920028050U CN 209215736 U CN209215736 U CN 209215736U
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Abstract
The utility model discloses a kind of lenticule heeling-in collimators, including a fixing seat, the fixing seat side is fixedly connected with the first socket joint plate, the first socket joint board bottom end is plugged with first connecting rod, the first connecting rod bottom end is equipped with support platform, the angular displacement platform for being respectively used to adjust the angle is successively arranged in the support platform from bottom to up, vertical displacement platform of the horizontal displacement platform and Z axis of X/Y plane position to position, the vertical displacement platform side is fixedly connected with microscope clamper, the support platform bottom end and microscope clamper corresponding position are equipped with lenticule clamper.The utility model not only may be implemented to adjust mini microscope from five directions, but also can realize the adjustment to lenticule relative position, and can synchronize the installation of the heeling-in and mini microscope of realizing lenticule.
Description
Technical field
The utility model relates to Neurobiology experimental instrument field, specially a kind of lenticule heeling-in collimator.
Background technique
Lenticule and superminiature microscope can record the Ca2+ oscillations of neuron by imaging mode, and lenticule is imbedded at mouse
Brain, superminiature microscope is matched using the imaging realized to intracerebral neuron again, this technology is at home and abroad answered extensively
For in the neural Bioexperiment of mouse；When recording Ca2+ oscillations using this system, need to adjust lenticule and superminiature
Microscopical relative position makes superminiature microscope that can realize the higher imaging effect of contrast to neuron.
Currently, aforesaid operations manually adjust realization by experimenter, which has the disadvantage in that (1) due to micro-
Mirror and the microscopical size of superminiature are smaller, therefore realize that the manual registration operation of this system has certain difficulty, operational
Fault may result in can not accurate recording neuron Ca2+ oscillations；(2) it when testing, needs lenticule being first imbedded at mouse brain
It is interior, while it is micro- to mouse internal injection fluorescin, after waiting 1-2 weeks virus to express completely in Mice Body to install superminiature again
Mirror, the position of lenticule is almost non-adjustable at this time, it is likely that most apparent Ca2+ oscillations in mouse brain can not be recorded.Therefore,
Market in urgent need can be beneficial to the machine auxiliary conditioning unit of experiment.
Utility model content
The utility model solve the technical issues of be to overcome defect of the existing technology, a kind of lenticule heeling-in is provided
Collimator.The present apparatus not only may be implemented to adjust mini microscope from five directions, but also can realize opposite to lenticule
The adjustment of position, and the installation of the heeling-in and mini microscope of realizing lenticule can be synchronized.
To achieve the above object, the utility model provides the following technical solutions: a kind of lenticule heeling-in collimator, including one
Fixing seat, the fixing seat side are fixedly connected with the first socket joint plate, and the first socket joint board bottom end is plugged with first connecting rod,
The first connecting rod bottom end is equipped with support platform, is successively arranged from bottom to up in the support platform and is respectively used to adjust the angle
Angular displacement platform, to the vertical displacement platform of position, the vertical displacement is flat for the horizontal displacement platform and Z axis of X/Y plane position
Platform side is fixedly connected with microscope clamper, and the support platform bottom end and microscope clamper corresponding position are equipped with micro-
Mirror clamper.
Preferably, the microscope clamper includes the second socket joint plate, and the second socket joint board bottom end is plugged with the second company
Extension bar, second connecting rod bottom end are connected with microscope fixture block.
Preferably, the lenticule clamper includes main folder head and sub-folder head, and the main folder head and sub-folder head the same end
Portion is mounted by means of bolts on the support platform bottom end.
Preferably, the side on the vertical displacement platform far from microscope clamper is fixedly installed with balance weight, and institute
State opened up inside balance weight it is fluted.
Compared with prior art, the utility model has the beneficial effects that the present apparatus not only may be implemented from five direction tune
Save superminiature microscope, and can realize the adjustment to lenticule relative position, thus can synchronize the heeling-in for realizing lenticule and
The microscopical installation of superminiature, can simplify the workflow of experimenter by the present apparatus, while also improve the detection of system
Sensitivity.
Detailed description of the invention
Fig. 1 is the left view of lenticule heeling-in collimator in an embodiment of the present invention；
Fig. 2 is the right view of lenticule heeling-in collimator in an embodiment of the present invention；
Fig. 3 is the explosive view of lenticule heeling-in collimator in an embodiment of the present invention；
Fig. 4 is angular displacement platform structure schematic diagram in an embodiment of the present invention.
Figure label: 1- fixing seat, 2- the first socket joint plate, 3- first connecting rod, 4- support platform, 5- angular displacement platform,
51- first angle knob, 52- second angle knob, the first slide unit of 53-, the centre 54- guiding parts, the second sliding part of 55-
Part, 6- horizontal displacement platform, 7- vertical displacement platform, 8- balance weight, 9- microscope clamper, 91- the second socket joint plate, 92-
Two connecting rods, 93- microscope fixture block, 10- lenticule clamper, 101- main folder head, 102- sub-folder head, 11- groove.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.
As shown in Figure 1-3, the utility model provides a kind of technical solution: a kind of lenticule heeling-in collimator, including one is solid
Reservation 1,1 side of fixing seat are fixedly connected with the first socket joint plate 2, and 2 bottom end of the first socket joint plate is plugged with first connecting rod 3, and first
3 bottom end of connecting rod is equipped with support platform 4, is successively arranged the angular displacement for being respectively used to adjust the angle in support platform 4 from bottom to up
Platform 5, the horizontal displacement platform 6 and Z axis of X/Y plane position to the vertical displacement platform 7 of position, consolidate by 7 side of vertical displacement platform
Surely it is connected with microscope clamper 9,4 bottom end of support platform and 9 corresponding position of microscope clamper are equipped with lenticule clamper
10。
Wherein, microscope clamper 9 includes the second socket joint plate 91, and 91 bottom end of the second socket joint plate is plugged with the second connecting rod
92,92 bottom end of the second connecting rod is connected with microscope fixture block 93, and microscope can be directly fastened on microscope fixture block 93；It is micro-
Mirror clamper 10 includes main folder head 101 and sub-folder head 102, and main folder head 101 is bolted with the same end of sub-folder head 102
It is mounted on 4 bottom end of support platform, lenticule can be made to be clamped between main folder head 101 and sub-folder head 102 by adjusting bolt,
The lenslet diameter that lenticule clamper 10 can clamp is within the scope of 0.5mm~5mm.
Referring to Fig. 4, angular displacement platform 5 is followed successively by the first slide unit 53, arcuate guide from the bottom to top in the present embodiment
Component 54 and the second slide unit 55,54 lower part of arcuate guide component is equipped with arc groove, and upper part is equipped with arc bump, arc
The centre of sphere of connected in star and the centre of sphere of arc bump coincide, and the two rotary shaft intersection and it is vertical；
The top of first slide unit 53 and the lower part of the second slide unit 55 respectively with arc groove and arc bump phase
Matching, and the male character types in Chinese operas, usu. referring tov the bearded character displacement, the first slide unit 53 and the second sliding part are issued in the guiding of arc groove and arc bump respectively
The side of part 55 is respectively provided with the first angle knob 51 and second angle knob 52 for adjusting angle, and angle adjustable range is
± 15 °, angle adjusting accuracy is 0.05 °；
Correspondingly, horizontal displacement platform 6 is equipped with the knob for being respectively used to adjust X and Y-axis position, vertical displacement platform
7 vertical direction be equipped with for adjust knob of the Z axis to position, X, Y and Z axis to position-adjustable range be ± 5mm, accurately
Degree is 0.02mm.
It should be noted that being all made of ball screw arrangement inside angular displacement platform 5 and horizontal displacement platform 6 to realize and pass
Dynamic, vertical displacement platform is driven using screw rod mode.
Further, in order to keep the stabilization of collimator, the side far from microscope clamper is solid on vertical displacement platform 7
Dingan County is equipped with balance weight 8, and fluted 11 are opened up inside balance weight 8.
The experimental implementation process of the utility model is as follows:
Firstly, lenticule is fixed on 10 front end of lenticule clamper, according to embedding lenticule diameter, lead to
The screw at adjustment 10 rear portion of lenticule clamper is crossed to adjust the openings of sizes of lenticule clamper 10, then by mini microscope mirror
Body is fixed on microscope clamper 9, has a screwing screw to play fixed mini microscope mirror body beside microscope clamper 9
Effect；It is moved to by adjusting angular displacement platform 5, horizontal displacement platform 6 and vertical displacement platform 7 for mini microscope mirror body micro-
Above lens, logging software is opened, and light source is opened, places a fluorescence sample, below lenticule for adjusting focal length.
In conclusion purpose is ensuring that miniature micro- by the adjustment on this five directions to mini microscope mirror body
It is completely vertical between lens head and lenticule, it is ensured that optimal imaging effect, and pass through this mirror body and lenticule separate type
Delicate control method, increase integral experiment operation convenience, controllability and accuracy, to go on smoothly burying for lenticule
It sets experiment and provides reliable guarantee.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (4)
1. a kind of lenticule heeling-in collimator, including a fixing seat (1), fixing seat (1) side is fixedly connected with first and holds
Plate (2), the first socket joint plate (2) bottom end are plugged with first connecting rod (3), and first connecting rod (3) bottom end is equipped with branch
It supports platform (4), it is characterised in that: be successively arranged the angle position for being respectively used to adjust the angle on the support platform (4) from bottom to up
It moves platform (5), vertical displacement platform (7) of the horizontal displacement platform (6) and Z axis of X/Y plane position to position, the vertical position
It moves platform (7) side to be fixedly connected with microscope clamper (9), support platform (4) bottom end and microscope clamper (9) are right
Answer position that lenticule clamper (10) are installed.
2. a kind of lenticule heeling-in collimator according to claim 1, it is characterised in that: the microscope clamper (9)
Including the second socket joint plate (91), the second socket joint plate (91) bottom end is plugged with the second connecting rod (92), second connecting rod
(92) bottom end is connected with microscope fixture block (93).
3. a kind of lenticule heeling-in collimator according to claim 1, it is characterised in that:
The lenticule clamper (10) includes main folder head (101) and sub-folder head (102), and the main folder head (101) and sub-folder
Head (102) same end is mounted by means of bolts on the support platform (4) bottom end.
4. a kind of lenticule heeling-in collimator according to claim 1, it is characterised in that: the vertical displacement platform (7)
The upper side far from microscope clamper (9) is fixedly installed with balance weight (8), and is opened up inside the balance weight (8) fluted
(11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920028050.9U CN209215736U (en) | 2019-01-08 | 2019-01-08 | A kind of lenticule heeling-in collimator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920028050.9U CN209215736U (en) | 2019-01-08 | 2019-01-08 | A kind of lenticule heeling-in collimator |
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| Publication Number | Publication Date |
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| CN209215736U true CN209215736U (en) | 2019-08-06 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114287881A (en) * | 2021-12-11 | 2022-04-08 | 中国科学院深圳先进技术研究院 | Micro single-photon fluorescence microscope implantation device and implantation method |
| WO2024108468A1 (en) * | 2022-11-24 | 2024-05-30 | 中国科学院深圳先进技术研究院 | Clamping groove clamping device of single-photon fluorescence microscope and clamping groove mounting method therefor |
-
2019
- 2019-01-08 CN CN201920028050.9U patent/CN209215736U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114287881A (en) * | 2021-12-11 | 2022-04-08 | 中国科学院深圳先进技术研究院 | Micro single-photon fluorescence microscope implantation device and implantation method |
| CN114287881B (en) * | 2021-12-11 | 2024-03-15 | 中国科学院深圳先进技术研究院 | Miniature single photon fluorescence microscope implantation device and implantation method |
| WO2024108468A1 (en) * | 2022-11-24 | 2024-05-30 | 中国科学院深圳先进技术研究院 | Clamping groove clamping device of single-photon fluorescence microscope and clamping groove mounting method therefor |
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