CN209182282U - A kind of high precision electro chemistry blood ketone body test paper with hematocrit value compensation - Google Patents
A kind of high precision electro chemistry blood ketone body test paper with hematocrit value compensation Download PDFInfo
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- CN209182282U CN209182282U CN201821570231.6U CN201821570231U CN209182282U CN 209182282 U CN209182282 U CN 209182282U CN 201821570231 U CN201821570231 U CN 201821570231U CN 209182282 U CN209182282 U CN 209182282U
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Abstract
The utility model belongs to electrochemical technology field; a kind of high precision electro chemistry blood ketone body test paper with hematocrit value compensation is disclosed, from the bottom to top successively by substrate layer, measurement reaction cavity, the electrode layer of working electrode, enzyme layer, coating and for protecting the spacer layer of coating upper end to be sticked to form.According to end of sucking blood top distance by remote sequence being closely successively electrochemistry to electrode and trigger electrode, electrochemical working electrode, electrochemistry to electrode, trigger electrode with connect electrode, it connects electrode to be arranged at the insertion end of electrode layer, for starting electrochemical test.General measure section by hematocrit value because influenced, be typically only capable to work just can guarantee precision between 20%-50%, and after being compensated by hematocrit value, the range that 10%-70% can be reached guarantees measurement accuracy, the scope of application is greatly expanded, has positive meaning to the detection of baby, pregnant women, the higher relatively low crowd of old man's hematocrit value.
Description
Technical field
The utility model belongs to electrochemical technology field more particularly to a kind of high-precision electrification with hematocrit value compensation
Learn blood ketone body test paper.
Background technique
Currently, the prior art commonly used in the trade is such thatDiabetic about 11% will cause Diabetic ketosis
Acid poisoning (Diabetic ketoacidosis, DKA).Diabetic ketoacidosis is a kind of acute complications of diabetes, is
The acid poisoning of the excitation of severe insulin deficiency caused by blood glucose sharply increases.There is no enough insulin, body is in order to obtain energy
It measures and reduces fat, lipolysis generates ketoboidies, and when ketoplasia is more than to utilize, ketoboidies accumulation in blood becomes ketosis, by ketone
Volume is poly- to cause metabolic acidosis, becomes diabetic ketoacidosis.It is common with type 1 diabetes, serious person can concurrently suffer a shock,
Acute renal failure etc. can lead to death if treatment is not in time.Its general mortality rate is about 5%-10%, in the elderly then more
Height can reach 20% or so.If patient using abdominal pain as First presentation, or merge respiratory tract, enteron aisle, skin infection when, it is primary
The diagnosis of diabetes be easily ignored clinically easily fail to pinpoint a disease in diagnosis, mistaken diagnosis.Therefore early diagnosis, actively treatment are to treatment Diabetic ketosis
Acid poisoning, the reduction death rate and residual sick rate are particularly important.
In conclusion problem of the existing technology is:
(1) hematocrit value can form measurement accuracy and influence；
(2) hematocrit value computational accuracy is not high enough；
(3) interference elimination of the enzyme layer reaction to hematocrit value technology；
Solve the difficulty and meaning of above-mentioned technical problem:
The measurement of hematocrit value becomes realization measurement since test paper itself enzyme reaction will greatly affect conductivity measurement
Maximum interference source, it is therefore desirable to test paper design and measure on optimize.After hematocrit value measurement is accurate, compensate
Test paper measurement target user can greatly be improved.
Utility model content
In view of the problems of the existing technology, the utility model provides a kind of high precision electro with hematocrit value compensation
Chemical blood ketone body test paper.
The utility model is realized in this way a kind of high precision electro chemistry blood ketone body test paper with hematocrit value compensation,
It is described with hematocrit value compensation high precision electro chemistry blood ketone body test paper be bonded from the bottom to top substrate layer, measurement reaction cavity,
Electrode layer, enzyme layer, coating and the spacer layer for protecting coating upper end of working electrode.
Further, the measurement reaction cavity includes a pair of for measuring the electrode of conductivity.
Further, the electrode layer is gold electrode layer, carbon silver electrode.
Further, using polyethylene terephthalate, polyvinyl chloride, the substrate of any one material in polypropylene
Layer.
Further, there is stomata in the coating upper end.
Further, the measured zone for measuring conductivity does not cover enzyme layer.
In conclusion the advantages of the utility model and good effect are as follows:
1, general measure section is typically only capable to work ability between 20%-50% because being influenced by hematocrit value
Guarantee precision, and after being compensated by hematocrit value, the range that can reach 10%-70% guarantees measurement accuracy, greatly expands
The scope of application, to the detection of baby, pregnant women, the higher relatively low crowd of old man's hematocrit value has positive meaning.
Detailed description of the invention
Fig. 1 is the high precision electro chemistry blood ketone body test paper knot provided by the embodiment of the utility model with hematocrit value compensation
Structure schematic diagram；
In figure: 1, substrate layer；2, electrode is connected；3, electrochemical working electrode；4, switch electrode；5, trigger electrode；6, electric
Chemistry is to electrode；7, blood siphon port；8, conductance measurement region；9, enzyme layer；10, stomata；11, coating；12, spacer layer.
Specific embodiment
For the utility model content, feature and effect that can further appreciate that the utility model, the following examples are hereby given, and
It is described in detail with the accompanying drawings as follows.
The utility model is using the measurement correction of alternating signal motional impedance, according to blood conductance measurement hematocrit value
(HCT) blood high-precision ketoboidies (beta hydroxybutyric acid) the measurement test paper of some correction is carried out.
As shown in Figure 1, the high precision electro chemistry blood ketone body provided by the embodiment of the utility model with hematocrit value compensation
Test paper include: substrate layer 1, connect electrode 2, electrochemical working electrode 3, trigger electrode 4, switch electrode 5, electrochemistry to electrode 6,
Blood siphon port 7, conductance measurement region 8, enzyme layer 9, stomata 10, coating 11, spacer layer 12.
From the bottom to top successively by substrate layer 1, measurement reaction cavity, the electrode layer of working electrode, enzyme layer 9,11 and of coating
For protecting the spacer layer 12 of 11 upper end of coating to be sticked to form.
Enzyme solution is covered in measurement reaction cavity inner surface (except conductance measurement area)；Measurement reaction cavity is used for including a pair
Measure the electrode of conductivity.
Electrode layer is preferably gold electrode layer, alternatively there is carbon silver electrode.
Substrate layer 1 preferably uses polyethylene terephthalate, polyvinyl chloride, the base of any one material in polypropylene
Lamella.
Electrode layer is preferably by trigger electrode 5, electrochemistry to electrode 6, ketoboidies (beta hydroxybutyric acid) measurement electrochemical operation electricity
Pole 3, electrochemistry are to electrode 6, and trigger electrode 5 is formed with the connection of electrode 2 is connected, and according to the distance on the top at end of sucking blood by closely extremely
Remote sequence is successively electrochemistry to electrode 6 and trigger electrode 5, and electrochemical working electrode 3, electrochemistry is to electrode 6, trigger electrode
5 with connect electrode 2, connect electrode and be arranged at the insertion end of electrode layer, for starting electrochemical test.
There is stomata 10 in 11 upper end of coating.
The application principle of the utility model is further described with reference to the accompanying drawing.
Substrate layer 1: it uses polyethylene terephthalate (PET), polyvinyl chloride (PVC), one of polypropylene (PP).
Electrode layer: carbon, underclad portion silver electrode are selected using material selection upper layer of material.Blood is by blood siphon port 7
It is inhaled into test paper, by measuring reaction cavity, electrode convection current is tested to the conductivity that electrode 6 forms by trigger electrode 5, electrochemistry
The blood for being measured reaction cavity carries out the measurement of hematocrit (HCT), and then blood enters ketoboidies (beta hydroxybutyric acid) electricity
Cavity is chemically reacted, ketoboidies (beta hydroxybutyric acid) electrochemical reaction cavity includes an electrochemical working electrode 3, an electrochemistry
To electrode 6.Electrochemical working electrode 3 is ketoboidies (beta hydroxybutyric acid) measurement working electrode, and electrochemistry is ketoboidies to electrode 6
(beta hydroxybutyric acid) is measured to electrode；The test value that HCT is finally utilized on corresponding tester, by HCT to blood sugar concentration
Influence curve calibrate ketoboidies (beta hydroxybutyric acid) measured value, final entry and display be on a tester.
Trigger electrode 5 is located at the bottom of ketoboidies (beta hydroxybutyric acid) reaction zone (namely 9 reaction zone of enzyme layer), works as blood
5 test paper of trigger electrode that bottom must be reached after from top into end of sucking blood can just issue measurement countdown to corresponding ketoboidies
(beta hydroxybutyric acid) tester, tester start countdown test, and the design of trigger electrode 5 can not be filled to avoid due to blood
Measured value inaccuracy caused by entire reaction zone；One of bottom connected electrode 2 and be located at test paper, when test paper is inserted into phase
The tester answered connects electrode 2 and is connected with the both ends of disconnecting circuit in tester, so that the circuit structure of test paper circuit and tester
At complete circuit, instrument will Auto Power On, extract test strips after being measured out, instrument will automatic shutdown.Connect electrode 2
A part cover one layer of insulating film and be used to prevent the oxidation of electrode.
The region of electrochemical reaction occurs for 9 region of enzyme layer, that is, ketoboidies (beta hydroxybutyric acid).
Coating 11 is used to covering part electrode layer, and there is a stomata 10 in the front end of coating 11, enters for blood is discharged
Air when siphon passage, wherein the part of the unlapped electrode layer of stomata 10 forms the reaction zone with end open at one end,
It is exactly the region that enzyme layer 9 is arranged.
Spacer layer 12 is positioned over the upper end of layer 11, for protecting reaction zone not by the interference of external environment.
The above is only the preferred embodiment to the utility model, is not made in any form to the utility model
Limitation, it is all according to the technical essence of the utility model any simple modification made to the above embodiment, equivalent variations with
Modification, is all within the scope of the technical scheme of the utility model.
Claims (1)
1. a kind of high precision electro chemistry blood ketone body test paper with hematocrit value compensation, which is characterized in that the band red blood cell ratio
The high precision electro chemistry blood ketone body test paper for holding compensation is bonded the electrode of substrate layer, measurement reaction cavity, working electrode from the bottom to top
Layer, enzyme layer, coating and the spacer layer for protecting coating upper end；
The measurement reaction cavity includes a pair of for measuring the electrode of conductivity；
The electrode layer is gold electrode layer, carbon silver electrode；
Using polyethylene terephthalate, polyvinyl chloride, the substrate layer of any one material in polypropylene；
There is stomata in the coating upper end.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821570231.6U CN209182282U (en) | 2018-09-26 | 2018-09-26 | A kind of high precision electro chemistry blood ketone body test paper with hematocrit value compensation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821570231.6U CN209182282U (en) | 2018-09-26 | 2018-09-26 | A kind of high precision electro chemistry blood ketone body test paper with hematocrit value compensation |
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| Publication Number | Publication Date |
|---|---|
| CN209182282U true CN209182282U (en) | 2019-07-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821570231.6U Active CN209182282U (en) | 2018-09-26 | 2018-09-26 | A kind of high precision electro chemistry blood ketone body test paper with hematocrit value compensation |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113588748A (en) * | 2021-07-12 | 2021-11-02 | 成都云芯医联科技有限公司 | Full blood triggered electrochemical test paper |
-
2018
- 2018-09-26 CN CN201821570231.6U patent/CN209182282U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113588748A (en) * | 2021-07-12 | 2021-11-02 | 成都云芯医联科技有限公司 | Full blood triggered electrochemical test paper |
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