CN209178401U - A kind of culture bottle examined fastly suitable for medical device sterile - Google Patents
A kind of culture bottle examined fastly suitable for medical device sterile Download PDFInfo
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- CN209178401U CN209178401U CN201821879862.6U CN201821879862U CN209178401U CN 209178401 U CN209178401 U CN 209178401U CN 201821879862 U CN201821879862 U CN 201821879862U CN 209178401 U CN209178401 U CN 209178401U
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- Prior art keywords
- bottle
- circle
- culture bottle
- medical device
- culture
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- 238000001514 detection method Methods 0.000 claims abstract description 24
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 18
- 239000011159 matrix material Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 229920000642 polymer Polymers 0.000 claims description 6
- 238000011161 development Methods 0.000 claims description 5
- 239000001963 growth medium Substances 0.000 claims description 4
- 230000005540 biological transmission Effects 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 4
- 239000003292 glue Substances 0.000 claims 4
- 229910052710 silicon Inorganic materials 0.000 claims 4
- 239000010703 silicon Substances 0.000 claims 4
- 239000012528 membrane Substances 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 abstract description 3
- 238000013190 sterility testing Methods 0.000 abstract description 2
- 230000001954 sterilising effect Effects 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 230000012010 growth Effects 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241001411320 Eriogonum inflatum Species 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 108010025899 gelatin film Proteins 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A kind of culture bottle examined fastly suitable for medical device sterile, including transparent vial body are provided with bottle cap in the transparent vial body upper end, and the bottle cap and transparent vial body are connected through a screw thread；The bottom of the transparent vial body is provided with pellosil circle, the cross section of the pellosil circle is semiclosed shape, and the bottom of bottle of the pellosil circle and the transparent vial body forms closed annular region, is provided with detection reagent in the annular region.The pellosil circle in conjunction with the culture bottle, is formed it into closed structure by the utility model, and when detecting colour developing, the color can check monitoring by bottom of bottle or bottle wall.Culture bottle described in the utility model can be applied smoothly in vibration culture, detection limit is greatly improved together in conjunction with vibration culture systems and shortens detection cycle, it was improved from 7 days or so within 24 hours by conventional Sterility testing, significantly improves the efficiency of medical device sterile detection.
Description
Technical field
The utility model relates to a kind of culture bottles examined fastly suitable for medical device sterile, belong to the skill of medical instrument detection
Art field.
Background technique
The sterilization validation and sterilising cycle monitoring needs of most of medical instrument use bionidicator, and biology refers to after sterilizing
Show that the sterility test of object is of great significance for the sterilizing of medical instrument.When establishing sterilizing dose for sterilizing or to verify this one
When the conventional validity or product of amount are let pass, all need to carry out sterility test to microbial administration bacterium piece.It is existing conventional sterile fast
The application method of the culture bottle of inspection is: by microbial administration bacterium piece as in the culture bottle, then sample to be tested and life will be housed
The culture bottle of object indicator bacteria piece, which is placed in culture apparatus, to be cultivated.However as the promotion that detection technique requires, this technology neck
Domain is also begun to focus on: how to guarantee the technical issues of detection efficiency is significantly promoted while detection accuracy, for this purpose, applicant opens
The mode for beginning to set about research and utilization vibration culture stablizes the culture bottle equipped with sample to be tested and microbial administration bacterium piece
Culture.Compared to stationary culture, to culture bottle, there has also been further technical requirements for vibration culture: for example, the sealing of culture bottle
The stability etc. of detection reagent in property, culture bottle.To sum up, existing culture bottle is closed only with rubber plug, after culture, experiment
Personnel need to carry out eye-observation experimental result through bottle body, or the substance extracted in culture bottle detect outside bottle.Obviously,
Existing culture bottle structure is difficult to break through above-mentioned incubation and cultivation results efficiency.
Utility model content
In view of the deficiencies of the prior art, the utility model discloses a kind of culture bottle examined fastly suitable for medical device sterile.
The technical solution of the utility model is as follows:
A kind of culture bottle examined fastly suitable for medical device sterile, including transparent vial body are set in the transparent vial body upper end
It is equipped with bottle cap, the bottle cap and transparent vial body are connected through a screw thread；The bottom of the transparent vial body is provided with pellosil circle, institute
The cross section for stating pellosil circle is semiclosed shape, and the bottom of bottle of the pellosil circle and the transparent vial body forms closed annulus
Domain is provided with detection reagent in the annular region.The utility model in conjunction with the culture bottle, makes the pellosil circle
It forms closed structure, and when detecting colour developing, the color can check monitoring by bottom of bottle or bottle wall.
Preferred according to the utility model, the cross section of the pellosil circle is L shape.
Preferred according to the utility model, the cross section of the pellosil circle is arc-shaped.
Preferred according to the utility model, the pellosil circle is polymer matrix.
Preferred according to the utility model, the polymer matrix is to allow CO2The film of transmission, the detection reagent are
PH value development process value colour reagent.CO2It can pass through pellosil, when there is microorganism growth in the culture bottle, the CO that releases2
Pellosil is infiltrated into after water saturation, generates hydrogen ion (H+) change pH value in pellosil circle enclosure space, make described
Detection reagent color changes, and by color change calculating, whether there is or not microorganism growths.
It is preferred according to the utility model, culture medium layer is additionally provided in the culture bottle.
The utility model has the technical advantages that:
1, culture bottle described in the utility model can be applied smoothly in vibration culture, unified in conjunction with vibration training system
It rises and greatly improves detection limit and shorten detection cycle, improved from 7 days or so within 24 hours by conventional Sterility testing, substantially
Degree improves the efficiency of medical device sterile detection.
2, the utility model combines the actual features of vibration culture, transform the covering part of existing culture bottle as spiral side
Formula connection, to improve sealing performance, at the same time it can also screw off bottle stopper, direct plunges into it for biological bacteria piece convenient for experimenter
In carry out corresponding experiment.
3, the polymer matrix of polymorphic structure is arranged in the utility model in culture bottle, completely with culture bottle bottle wall and bottle
Bottom fitting, the detection reagent is fixed in culture bottle, while not interfering sample to be tested in observation bottle, moreover it is possible to accurate
Know the colour developing mark of detection reagent, while culture solution and reagent colour development situation can also be observed simultaneously in bottom of bottle.The structure can also
Guarantee the culture bottle in all angles vibration, the pellosil circle consolidates, seals the detection reagent, greatly improves Ben Pei
Support accuracy of the bottle in qualitative experiment.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of culture bottle described in the utility model embodiment 1；
Fig. 2 is the structural schematic diagram of culture bottle described in the utility model embodiment 2；
In Fig. 1,2,1, transparent vial body；2, bottle cap；3, pellosil circle；4, indicator is detected；5, culture medium layer.
Specific embodiment
The utility model is described in detail below with reference to embodiment and Figure of description, but not limited to this.
Embodiment 1,
As shown in Figure 1, 2.
A kind of culture bottle examined fastly suitable for medical device sterile, including transparent vial body 1, in 1 upper end of transparent vial body
It is provided with bottle cap 2, the bottle cap 2 and transparent vial body 1 are connected through a screw thread；The bottom of the transparent vial body 1 is provided with silica gel
Film circle 3, the cross section of the pellosil circle 3 are semiclosed shape, and the bottom of bottle formation of the pellosil circle and the transparent vial body is sealed
The annular region closed is provided with detection reagent 4 in the annular region.
The pellosil circle is polymer matrix.The polymer matrix is to allow CO2The film of transmission, the detection
Reagent is pH value development process value colour reagent.CO2It can pass through pellosil, when there is microorganism growth in the culture bottle, release
CO out2Pellosil is infiltrated into after water saturation, generates hydrogen ion (H+) change pellosil circle enclosure space in pH value,
The detection reagent color is set to change, whether there is or not microorganism growths by color change calculating.
When producing the culture bottle, the silica gel ring 3 is wrapped up into the bottom that the detection reagent 4 fills in the culture bottle together
Portion makes the silica gel ring 3 form closed area, and then above-mentioned pH value development process value colour developing may be implemented.The pellosil circle 3
Cross section is L shape.
Embodiment 2,
As shown in Figure 2.
A kind of culture bottle examined fastly suitable for medical device sterile as described in Example 1, distinguishes and is, the silica gel
The cross section of film circle 3 is arc-shaped.
Embodiment 3,
A kind of culture bottle examined fastly suitable for medical device sterile as described in embodiment 1,2, difference is, described
Culture medium layer 5 is additionally provided in culture bottle.
Claims (6)
1. a kind of culture bottle examined fastly suitable for medical device sterile, including transparent vial body, which is characterized in that in the clear vial
Body upper end is provided with bottle cap, and the bottle cap and transparent vial body are connected through a screw thread；The bottom of the transparent vial body is provided with silicon
Glue film circle, the cross section of the pellosil circle are semiclosed shape, and the bottom of bottle formation of the pellosil circle and the transparent vial body is sealed
The annular region closed is provided with detection reagent in the annular region.
2. a kind of culture bottle examined fastly suitable for medical device sterile according to claim 1, which is characterized in that the silicon
The cross section of glue film circle is L shape.
3. a kind of culture bottle examined fastly suitable for medical device sterile according to claim 1, which is characterized in that the silicon
The cross section of glue film circle is arc-shaped.
4. a kind of culture bottle examined fastly suitable for medical device sterile according to claim 1, which is characterized in that the silicon
Glue film circle is polymer matrix.
5. a kind of culture bottle examined fastly suitable for medical device sterile according to claim 4, which is characterized in that the height
Molecule semi-permeable membrane is to allow CO2The film of transmission, the detection reagent are pH value development process value colour reagent.
6. a kind of culture bottle examined fastly suitable for medical device sterile according to claim 1, which is characterized in that described
Culture medium layer is additionally provided in culture bottle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821879862.6U CN209178401U (en) | 2018-11-15 | 2018-11-15 | A kind of culture bottle examined fastly suitable for medical device sterile |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821879862.6U CN209178401U (en) | 2018-11-15 | 2018-11-15 | A kind of culture bottle examined fastly suitable for medical device sterile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209178401U true CN209178401U (en) | 2019-07-30 |
Family
ID=67364478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821879862.6U Active CN209178401U (en) | 2018-11-15 | 2018-11-15 | A kind of culture bottle examined fastly suitable for medical device sterile |
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| Country | Link |
|---|---|
| CN (1) | CN209178401U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109306319A (en) * | 2018-11-15 | 2019-02-05 | 山东省医疗器械产品质量检验中心 | The fast check system of medical device sterile and its application method |
| CN113174322A (en) * | 2021-04-13 | 2021-07-27 | 浙江泰林医学工程有限公司 | Rapid sterility detection system and method |
| CN113637722A (en) * | 2021-06-15 | 2021-11-12 | 山东省医疗器械和药品包装检验研究院 | Method for detecting sterility of pipeline and container medical instruments |
-
2018
- 2018-11-15 CN CN201821879862.6U patent/CN209178401U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109306319A (en) * | 2018-11-15 | 2019-02-05 | 山东省医疗器械产品质量检验中心 | The fast check system of medical device sterile and its application method |
| CN113174322A (en) * | 2021-04-13 | 2021-07-27 | 浙江泰林医学工程有限公司 | Rapid sterility detection system and method |
| CN113637722A (en) * | 2021-06-15 | 2021-11-12 | 山东省医疗器械和药品包装检验研究院 | Method for detecting sterility of pipeline and container medical instruments |
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Effective date of registration: 20240103 Granted publication date: 20190730 |