CN208851462U - A kind of fluoroscopic imaging device - Google Patents
A kind of fluoroscopic imaging device Download PDFInfo
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- CN208851462U CN208851462U CN201721306316.9U CN201721306316U CN208851462U CN 208851462 U CN208851462 U CN 208851462U CN 201721306316 U CN201721306316 U CN 201721306316U CN 208851462 U CN208851462 U CN 208851462U
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- light source
- optical filter
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- amici prism
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Abstract
It includes: light source module and optical signalling acquisition module that the utility model, which provides a kind of fluoroscopic imaging device,;Light source module includes: laser light source and visible light source, provides exciting light and visible light for search coverage;Optical signalling acquisition module includes: camera lens, Amici prism, reflecting mirror, the first CCD camera and the second CCD camera, the end of camera lens is connected with the incidence end of Amici prism, one exit end of Amici prism is connected to the first CCD camera, another exit end of Amici prism is connected to the second CCD camera by reflecting mirror.The utility model can carry out imaging and image co-registration to double spectrum simultaneously, obtain more fluorescence informations, extend the range of optical molecular image research and application.
Description
Technical field
The utility model relates to optical image technologies, are concretely a kind of fluoroscopic imaging devices.
Background technique
After radionuclide imaging, positron emission computerized tomography, single photon emission computed tomography and magnetic resonance imaging
Later, in recent years, molecular imaging technology continues to develop, one of the important mode as molecular image, optical molecular image skill
Art is increasingly becoming research hotspot, and wherein near-infrared fluorescence imaging receives much attention.
The fluoroscopic imaging systems of the prior art are mostly the monocular imaging systems for single wavelength, and the method utilized is to be directed to
The single wave band or interest wave band of dynamic process detect one by one, can not be for the progress of multiple wave bands while acquisition and to image
Fusion treatment is carried out, i.e., current fluorescent products most on the market are all made of monocular imaging system and are imaged, and disadvantage exists
It can only see fluorescent image or visible images when imaging, and can not see multispectral image.
Utility model content
For the threshold for reducing optical molecular imaging research, the range of optical molecular image research and application has been expanded, this
Utility model embodiment provides a kind of fluoroscopic imaging device, comprising: light source module, optical signalling acquisition module;
Light source module includes: laser light source and visible light source, for providing exciting light and visible light for search coverage;
Optical signalling acquisition module includes: camera lens, Amici prism, reflecting mirror, the first CCD camera and the second CCD camera,
The end of camera lens is connected with the incidence end of Amici prism, and an exit end of Amici prism is connected to the first CCD camera, light splitting
Another exit end of prism is connected to the second CCD camera by reflecting mirror.
In the utility model embodiment, light source module further include: the first optical filter and the second optical filter;
First optical filter is connected to the laser light source by laser fiber;
Second optical filter is connected to the visible light source by visible light optical fiber.
In the utility model embodiment, the spectral coverage of the first optical filter is 710nm-770nm, diameter 25mm;Second filters
The spectral coverage of piece is 400nm-650nm, diameter 25mm.
In the utility model embodiment, light source module optical signalling acquisition module further include: third optical filter and the 4th filter
Mating plate;
One exit end of Amici prism is connected to the first CCD camera by third optical filter;
Reflecting mirror is connected to the second CCD camera by the 4th optical filter.
In the utility model embodiment, the spectral coverage of third optical filter is 400nm-650nm, diameter 25mm;4th filters
The spectral coverage of piece is 810nm-870nm, diameter 25mm.
In the utility model embodiment, the visible light source is halogen light light source.
The utility model excites search coverage by light source module, carries out acquisition light in real time, optical filter module
The light of different spectral coverage is filtered, by the image co-registration of different spectral coverage to together, scientific research realizes the image co-registration of spectrum simultaneously
It is shown, fluorescence imaging is composed using binocular bifocal, imaging and image co-registration can be carried out to double spectrum simultaneously, obtained more glimmering
Optical information has broken offshore company in the technical monopoly situation of China, has extended the range of optical molecular image research and application.
For the above and other objects, features and advantages of the utility model can be clearer and more comprehensible, preferable reality is cited below particularly
Example is applied, and cooperates institute's accompanying drawings, is described in detail below.
Detailed description of the invention
In order to illustrate the embodiment of the utility model or the technical proposal in the existing technology more clearly, below will be to embodiment
Or attached drawing needed to be used in the description of the prior art is briefly described, it should be apparent that, the accompanying drawings in the following description is only
It is some embodiments of the utility model, for those of ordinary skill in the art, in the premise not made the creative labor
Under, it is also possible to obtain other drawings based on these drawings.
Fig. 1 is the block diagram that the utility model discloses a kind of fluoroscopic imaging device;
Fig. 2 is the block diagram of fluoroscopic imaging device in one embodiment of the utility model;
Fig. 3 is the structural block diagram that the utility model embodiment composes fluoroscopic imaging systems based on binocular bifocal;
Fig. 4 is the schematic diagram that the utility model embodiment composes fluoroscopic imaging systems based on binocular bifocal.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
The utility model discloses a kind of fluoroscopic imaging device, as shown in Figure 1, the device includes: light source module 101, optics
Signal acquisition module 102, wherein
Light source module includes: laser light source 1011 and visible light source 1012, for for search coverage provide exciting light and
Visible light;
Optical signalling acquisition module includes: camera lens 1021, Amici prism 1022, reflecting mirror 1023, the first CCD camera 1204
And the 2nd CCD1025 camera, the end of camera lens 1021 are connected with the incidence end of Amici prism 1022, Amici prism 1022
One exit end is connected to the first CCD camera 1024, another exit end of Amici prism 1022 is connected by reflecting mirror 1023
To the second CCD camera 1025;
In the utility model embodiment, the reflected light of search coverage is transmitted to Amici prism 1022 by camera lens 1021, the
The image that one CCD camera 1024 and the second CCD camera 1025 are acquired by Amici prism 1022 and reflecting mirror 1023 respectively, it is external
The image that can be acquired according to the first CCD camera 1024 and the 2nd CCD1025 of processing module 103 generate fluorescence imaging result.
Meanwhile as shown in Fig. 2, in one embodiment of the utility model, light source module further include: 1013 He of the first optical filter
Second optical filter 1014;
First optical filter 1013 is connected to laser light source 1011 by laser fiber;
Second optical filter 1014 is connected to visible light source 1012 by visible light optical fiber.
Light source module optical signalling acquisition module further include: third optical filter 1026 and the 4th optical filter 1027;
One exit end of Amici prism 1022 is connected to the first CCD camera 1027 by third optical filter 1026;
Reflecting mirror 1023 is connected to the second CCD camera 1024 by the 4th optical filter 1027.
The technical solution of the utility model is described in further details below with reference to specific embodiment.
It is proposed that a kind of binocular bifocal that is based on composes fluoroscopic imaging systems in the present embodiment, Fig. 3 is the utility model embodiment base
In binocular bifocal spectrum fluoroscopic imaging systems structural block diagram, Fig. 4 be the utility model embodiment be based on binocular bifocal compose fluorescence at
As the schematic diagram of system.
As shown, the binocular bifocal spectrum fluoroscopic imaging systems of the present embodiment include: that light source module 110, optical signalling are adopted
Collect module 120 and optical filter module 140, in which:
Light source module 110 is irradiated for the search coverage 100 to test serum, provides excitation for search coverage 100
Light and visible light;
Optical signalling acquisition module 120, for obtaining fluorescence and visible images according to the reflected light of search coverage 100;
External computer control is connect with processing module 130 with optical signalling acquisition module 120 by data line 101,
For in the optical signalling acquisition module 120 CCD camera 124 and CCD camera 127 control, optical signalling is adopted
The fluorescence and visible images that collection module 120 collects carry out fusion treatment and show;
Optical filter module 140, for providing the filter of different spectrum for light source module 110 and optical signalling acquisition module 120
Mating plate.
Light source module 110 further comprises: exciting light optical fiber 115, visible light optical fiber 116, optical filter 112, optical filter
114, excitation light source 113 and visible light source 111, wherein exciting light optical fiber is connect with optical filter 112, for being guided out exciting light
The exciting light that light source 113 issues, to carry out exciting light irradiation to search coverage 100;Visible light optical fiber is connect with optical filter 114,
The visible light issued for being guided out the visible light source 111 provides lighting source for search coverage 100;
Optical signalling acquisition module 120 further comprise camera lens 121, Amici prism 122, reflecting mirror 125, optical filter 123,
Optical filter 126, CCD camera 124, CCD camera 127, wherein Amici prism 122 is made of 55 Amici prisms, Amici prism 122
Incident light end be connected with the end of camera lens 122, two exit ends are separately connected optical filter 123 and reflecting mirror 125, optical filter
124 with CCD camera 124) be connected, the incident light end of reflecting mirror 125 is connected with an exit end of Amici prism 122, exit end
It is connected by optical filter 126 with the CCD camera 127, the Ray Of Light for transmitting camera lens 122 is divided into two beams;CCD camera
124) it controls with computer and is connect with processing module 130 with CCD camera 127, for according to Amici prism 122 and reflecting mirror 125
The emergent ray image transmitting with different spectrum or different-energy that is imaged, and will respectively obtained to external meter
The control of calculation machine and processing module 130.
The relative distance between each device in optical signalling acquisition module 120 be it is fixed, i.e., optical signal passes through mirror
Head enters in the system, is first converted into directional light, light is divided into two by Amici prism 122 and reflecting mirror 125
Beam is imaged by two CCD cameras respectively.So the optical signalling acquisition module 120 is a general light splitting mould
Block, i.e., no matter camera lens is selected as endoscope, C interface camera lens or F interface camera lens, can as long as being adjusted to suitable flange distance
Blur-free imaging on computers.
Optical filter module 140 is used for the exciting characteristic according to different fluorescence, adjusts the spectral coverage of each optical filter, double to guarantee
The excitation and acquisition of spectrum light, avoid interfering with each other for different spectrum lights.The spectral coverage of each optical filter once adjusted,
To no longer it switch during entire real time imagery.The quantity of the optical filter can be installed as needed, practical at this
In a novel embodiment, the quantity of the optical filter is 4: optical filter 112, optical filter 114, optical filter 123 and optical filter four
12, the spectral coverage of the optical filter is near infrared range, specifically:
The spectral coverage of optical filter 112 is 710nm-770nm, diameter 25mm;
The spectral coverage of optical filter 114 is 400nm-650nm, diameter 25mm;
The spectral coverage of optical filter 123 is 400nm-650nm, diameter 25mm;
The spectral coverage of optical filter 126 is 810nm-870nm, diameter 25mm;
Operator in actual use, can according to specific demand switch have suitable spectrum optical filter,
It is not limited with range described in the utility model embodiment.
The method for carrying out multispectral imaging using the multi-optical spectrum imaging system in the utility model embodiment based on endoscope,
Itself specifically includes the following steps:
Step S1 is irradiated exciting light sources 111 and visible light source 113 respectively to search coverage 100;
Step S2, according to detection feature, optical filter module 150 is for light source module 110, optical signalling acquisition module
(120) optical filter is configured in;
Step S3 is adjusted the imaging parameters of CCD camera 124 and CCD camera 127, the CCD camera 124 and CCD
Camera 127 according to the search coverage 100 there is the reflected light of different spectrum or energy to collect image respectively;
Step S4, external computer control is with processing module 130 to the CCD camera 124) and the acquisition of CCD camera 127
Obtained image carries out image co-registration processing;
Step S5, obtaining that treated for the step S4, image carries out real-time display, if the image of display is not up to
To clarity requirement, then the parameter of endoscope head 122 can be adjusted by optical signalling acquisition module 120, until display
Image reaches clarity requirement.
The characteristics of the utility model is according to optical molecular image, and based on for a long time in the research experience of optical imaging field,
The functions such as the acquisition for realizing fluorescence, visible light and split image using two CCD cameras.And provide it is a kind of it is general at
As system, i.e., no matter camera lens is selected as endoscope, C interface camera lens or F interface camera lens, as long as being adjusted to suitable flange distance,
Can blur-free imaging on computers, observed for staff.
The utility model excites search coverage by light source module, carries out acquisition light in real time, optical filter module
The light of different spectral coverage is filtered, by the image co-registration of different spectral coverage to the image co-registration and progress for together, realizing spectrum
Display.Current fluorescent products most on the market are all made of monocular imaging system and are imaged, its shortcoming is that when imaging only
It can see fluorescent image or visible images, and can not see multispectral image.And the utility model effective solution
The problem, while also having broken offshore company in the technical monopoly situation of China, the threshold of optical molecular imaging research is reduced, is opened up
The range of optical molecular image research and application is opened up.
Specific embodiment is applied in the utility model to be expounded the principles of the present invention and embodiment, with
The explanation of upper embodiment is merely used to help understand the method and its core concept of the utility model;Meanwhile for this field
Those skilled in the art, based on the idea of the present invention, there will be changes in the specific implementation manner and application range, comprehensive
Upper described, the content of the present specification should not be construed as a limitation of the present invention.
Claims (6)
1. a kind of fluoroscopic imaging device, which is characterized in that the device includes: light source module and optical signalling acquisition module;
Wherein,
The light source module includes: laser light source and visible light source, provides exciting light and visible light for search coverage;
The optical signalling acquisition module includes: camera lens, Amici prism, reflecting mirror, the first CCD camera and the 2nd CCD phase
Machine, the end of camera lens are connected with the incidence end of Amici prism, and an exit end of Amici prism is connected to the first CCD camera,
Another exit end of Amici prism is connected to the second CCD camera by reflecting mirror.
2. fluoroscopic imaging device as described in claim 1, which is characterized in that the light source module further include: first filters
Piece and the second optical filter;
First optical filter is connected to the laser light source by laser fiber;
Second optical filter is connected to the visible light source by visible light optical fiber.
3. fluoroscopic imaging device as claimed in claim 2, which is characterized in that
The spectral coverage of first optical filter is 710nm-770nm, diameter 25mm;
The spectral coverage of second optical filter is 400nm-650nm, diameter 25mm.
4. fluoroscopic imaging device as described in claim 1, which is characterized in that the light source module optical signalling acquisition module
Further include: third optical filter and the 4th optical filter;
One exit end of the Amici prism is connected to the first CCD camera by third optical filter;
The reflecting mirror is connected to the second CCD camera by the 4th optical filter.
5. fluoroscopic imaging device as claimed in claim 4, which is characterized in that
The spectral coverage of the third optical filter is 400nm-650nm, diameter 25mm;
The spectral coverage of 4th optical filter is 810nm-870nm, diameter 25mm.
6. fluoroscopic imaging device as described in claim 1, which is characterized in that the visible light source is halogen light light
Source.
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