CN208785315U - A kind of double-layer hollow capsule - Google Patents

A kind of double-layer hollow capsule Download PDF

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Publication number
CN208785315U
CN208785315U CN201820722722.1U CN201820722722U CN208785315U CN 208785315 U CN208785315 U CN 208785315U CN 201820722722 U CN201820722722 U CN 201820722722U CN 208785315 U CN208785315 U CN 208785315U
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capsule
layer
shell
capsule shell
double
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CN201820722722.1U
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刘利辉
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Zhejiang Kayun Pharmaceutical Ltd By Share Ltd
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Zhejiang Kayun Pharmaceutical Ltd By Share Ltd
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Abstract

The utility model relates to a kind of drug containers, more particularly, to a kind of double-layer hollow capsule.Including capsule ontology, the capsule ontology is spliced by about two corresponding separated capsules, the separated capsule outermost layer is the first capsule shell, it is in hollow form inside first capsule shell, it is internally provided with second capsule shell, several demarcation plates are equipped between first capsule shell and the second capsule shell, space between first capsule shell and the second capsule shell is separated into several and first sets medicine cavity by the demarcation plate, is equipped with one second inside second capsule shell and is set medicine cavity.The utility model has the following beneficial effects: a variety of drugs can be arranged in capsule in (1);(2) capsule is double-layer structure, can treat stomach trouble and intestines problem simultaneously;(3) distress level of patient over the course for the treatment of is slowed down.

Description

A kind of double-layer hollow capsule
Technical field
The utility model relates to a kind of drug containers, more particularly, to a kind of double-layer hollow capsule.
Background technique
Capsule shells are to be used to contain solid by what precision processing and auxiliary material were fabricated with the medicinal gelatin of food grade The ovate hollow casing of powder, particle.Capsule shells have good bioavilability, can rapidly, reliably and securely dissolve.
The drug filled with capsule, typically bad to esophagus and gastric mucosa powder excitatory or particle or mouthfeel, It is easy to volatilize, easily decomposed in the oral cavity by saliva, and the medicine of easily sucking tracheae.These medicines are packed into capsule, both protect drug Pharmacological property is not destroyed, and also protects digestive organs and respiratory tract.Remove capsule shells be likely to result in drug wastage, drug waste, Drug effect reduces.In addition, some drugs need to dissolve and absorb in the intestine, capsule protects drug not destroyed by gastric acid.Pharmaceutically refer to use Bladder made of extraordinary filmogen (such as gelatin, cellulose, polysaccharide etc.), content (such as powdery, liquid various kinds of drug Deng) or be according to dosage packed into wherein, convenient for swallowing.
But current capsule is usually single layer capsule, therefore a kind of drug can only be often placed inside it, therefore is being cured Patient generally requires to take a variety of different capsules simultaneously to reach therapeutic purposes when raw configuration drug.Meanwhile some drugs It needs to absorb in stomach, some drugs needs absorb in enteron aisle, therefore treat stomach trouble at the same time and liquid needs when intestines problem Different capsules is taken simultaneously.Considerably increase distress level of the patient in treatment.
Such as a kind of a kind of multi-functional capsule structure disclosed in Chinese patent literature, Authorization Notice No. are CN206214431U, the capsule ontology include capsule body and capsule cap, and the capsule body is sheathed in capsule cap, the capsule Outer body is equipped with layer protecting film, and capsule body and capsule cap fitting junction are equipped with a band, the capsule body and capsule Cap is equipped with reinforcing rib, and the capsule body interior is cavity, and one piece is equipped in the cavity with upper spacer.The utility model is protected The setting of cuticula and band further increases the leakproofness of capsule ontology, avoids falling off between capsule body and capsule cap The generation of phenomenon;The setting of reinforcing rib, improves capsule intensity, can effectively prevent capsule deformation;Partition is movably arranged, energy It is enough to be placed in capsule convenient for different types of drug is arranged in pairs or groups.Although being able to solve the existing of a part in the utility model to ask Topic, but it is single layer structure, can only digest in gastric juice or digest in enteron aisle simultaneously simultaneously, it is caused to treat at the same time There is still a need for take drug not of the same race when stomach trouble and intestines problem.Therefore, under certain conditions, still it is unable to satisfy and answers With.
Utility model content
The utility model be in order to overcome in the prior art capsule can only place a kind of drug, capsule be single layer therefore It can only be decomposed in the same digestive organs, patient's larger problem of distress level over the course for the treatment of, providing one kind can be A variety of drugs are arranged in capsule, and capsule is double-layer structure, can treat stomach trouble and intestines problem simultaneously, slow down patient and exist Distress level in therapeutic process.
To achieve the goals above, the utility model uses following technical scheme:
A kind of double-layer hollow capsule, including capsule ontology, the capsule ontology is by about two corresponding separated capsules Be spliced, it is in hollow form inside the first capsule shell that the separated capsule outermost layer, which is the first capsule shell, inside set There is second capsule shell, several demarcation plates are equipped between first capsule shell and the second capsule shell, it is described Space between first capsule shell and the second capsule shell is separated into several and first sets medicine cavity by demarcation plate, and described second One second, which is equipped with, inside capsule shell sets medicine cavity.
Capsule in the present invention is spliced by upper and lower two separated capsules, and separated capsule therein is in double-layer structure, the One the second capsule shell of capsule shell can dissolution to needs while being treated in stomach and enteron aisle to release drug respectively Under the occasion of stomach trouble and intestines problem, it can achieve the purpose that treatment in the case where eating least capsule quantity, to have Effect alleviates the distress level of patient over the course for the treatment of.The setting of demarcation plate enables to the first capsule shell and the simultaneously First between two capsule shells sets and can place different drugs inside medicine cavity, to achieve the effect that combined therapy.
Preferably, being equipped with one at the first capsule shell upper end opening in the separated capsule to outside the first capsule Flange on the outside of shell, the flange are equipped with a positioning column and locating slot.
The flange on the outside of the first capsule shell, which is arranged, can effectively enhance the mechanical strength of the first capsule shell, simultaneously Setting positioning column enables to upper and lower two separated capsules that can effectively be directed at buckle in splicing with locating slot, thus It will not be unrestrained there is a phenomenon where drug.
Preferably, positioning column engages in correspondence with each other with locating slot above and below the separated capsule when corresponding splicing, turn over It is fixedly connected on the outside of side by fixed ring.
Preferably, second capsule shell include from outside to inside porous propylene acid resin layer, chitosan layer and Gelatin layer.
Setting porous propylene acid resin enable to intestinal juice can through hole acrylate resin layer enter the second capsule, Have the function that discharge drug to gradually dissolve chitosan layer and gelatin layer.
Preferably, the porous propylene acid resin layer is equipped with several compact arranged through-holes, the diameter of through-hole is 0.05mm。
Preferably, being additionally provided with one between the porous propylene acid resin layer and chitosan layer by magnesium hydroxide system PH buffer layer made of standby.
The pH buffer layer being prepared by magnesium hydroxide, which is arranged, enables to the gastric acid in gastric juice not dissolve the second capsule Shell guarantees the phenomenon that drug to enter inside enteron aisle will not be precipitated again, lead to drug failure in stomach.
Therefore, the utility model has the following beneficial effects: a variety of drugs can be arranged in capsule in (1);(2) capsule For double-layer structure, stomach trouble and intestines problem can be treated simultaneously;(3) distress level of patient over the course for the treatment of is slowed down.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of the utility model.
Fig. 2 is the structural schematic diagram of the separated capsule of the utility model.
Fig. 3 is the top view of the utility model separated capsule.
Fig. 4 is the structural schematic diagram of second capsule shell of the utility model.
Fig. 5 is the structural schematic diagram of the porous propylene acid resin layer of the utility model.
Wherein: capsule ontology 1, separated capsule 2, the first capsule shell 3, the second capsule shell 4, demarcation plate 5, first set medicine Chamber 6, second set medicine cavity 7, flange 8, positioning column 9, locating slot 10, fixed ring 11, porous propylene acid resin layer 12, chitosan layer 13, gelatin layer 14, through-hole 15, pH buffer layer 16.
Specific embodiment
The utility model is further described with specific embodiment with reference to the accompanying drawing.
In embodiment as shown in Figs. 1-5, a kind of double-layer hollow capsule, including capsule ontology 1, the capsule ontology 1 It is spliced by about two corresponding separated capsules 2,2 outermost layer of separated capsule is the first capsule shell 3, the first glue It is in hollow form inside capsule shell 3, is internally provided with second capsule shell 4, the second capsule shell 4 includes porous from outside to inside Acrylate resin layer 12, chitosan layer 13 and gelatin layer 14, porous propylene acid resin layer 12 are equipped with several diameters and are 0.05mm compact arranged through-hole 15 is additionally provided with one by hydroxide between porous propylene acid resin layer 12 and chitosan layer 13 The pH buffer layer 16 that magnesium is prepared is equipped with several demarcation plates 5 between first capsule shell 3 and the second capsule shell 4, Space between first capsule shell 3 and the second capsule shell 4 is separated into several and first sets medicine cavity 6 by the demarcation plate 2, One second is equipped with inside second capsule shell 4 and sets medicine cavity 7, on the first capsule shell 3 in the separated capsule 2 A flange 8 to 3 outside of the first capsule shell is equipped at end opening, the flange is equipped with a positioning column 9 and positioning Slot 10, when described about the 2 corresponding splicing of separated capsule, positioning column 9 engages in correspondence with each other with locating slot 10,8 outside of flange It is fixedly connected by fixed ring 11.

Claims (6)

1. a kind of double-layer hollow capsule, characterized in that including capsule ontology (1), the capsule ontology (1) is by about two phases Corresponding separated capsule (2) are spliced, and the separated capsule (2) outermost layer is the first capsule shell (3), the first capsule shell (3) internal is in hollow form, is internally provided with second capsule shell (4), first capsule shell (3) and the second capsule Several demarcation plates (5) are equipped between shell (4), the demarcation plate (5) is by the first capsule shell (3) and the second capsule shell (4) space between is separated into several and first sets medicine cavity (6), and one second is equipped with inside second capsule shell (4) Set medicine cavity (7).
2. a kind of double-layer hollow capsule according to claim 1, characterized in that first in the separated capsule (2) One is equipped at capsule shell (3) upper end opening to the flange (8) on the outside of the first capsule shell (3), the flange is equipped with One positioning column (9) and locating slot (10).
3. a kind of double-layer hollow capsule according to claim 1 or 2, characterized in that the separated capsule (2) phase up and down When corresponding splicing, positioning column (9) engages in correspondence with each other with locating slot (10), connects on the outside of flange (8) by the way that fixed ring (11) are fixed It connects.
4. a kind of double-layer hollow capsule according to claim 1, characterized in that second capsule shell (4) is by outer To interior including porous propylene acid resin layer (12), chitosan layer (13) and gelatin layer (14).
5. a kind of double-layer hollow capsule according to claim 4, characterized in that the porous propylene acid resin layer (12) Several compact arranged through-holes (15) are equipped with, the diameter of through-hole (15) is 0.05mm.
6. a kind of double-layer hollow capsule according to claim 4 or 5, characterized in that the porous propylene acid resin layer (12) the pH buffer layer (16) being prepared by magnesium hydroxide is additionally provided between chitosan layer (13).
CN201820722722.1U 2018-05-15 2018-05-15 A kind of double-layer hollow capsule Active CN208785315U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820722722.1U CN208785315U (en) 2018-05-15 2018-05-15 A kind of double-layer hollow capsule

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820722722.1U CN208785315U (en) 2018-05-15 2018-05-15 A kind of double-layer hollow capsule

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CN208785315U true CN208785315U (en) 2019-04-26

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021017791A1 (en) * 2019-07-26 2021-02-04 温州芳植生物科技有限公司 Gastrointestinal tract sampling and drug releasing capsule
CN113164405A (en) * 2020-07-22 2021-07-23 绍兴康可胶囊有限公司 Hydroxypropyl methylcellulose hollow capsule
CN114711364A (en) * 2022-04-14 2022-07-08 安徽善和生物科技有限公司 Probiotics solid beverage capsule

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021017791A1 (en) * 2019-07-26 2021-02-04 温州芳植生物科技有限公司 Gastrointestinal tract sampling and drug releasing capsule
CN113164405A (en) * 2020-07-22 2021-07-23 绍兴康可胶囊有限公司 Hydroxypropyl methylcellulose hollow capsule
CN113164405B (en) * 2020-07-22 2022-09-06 绍兴康可胶囊有限公司 Hydroxypropyl methylcellulose hollow capsule
CN114711364A (en) * 2022-04-14 2022-07-08 安徽善和生物科技有限公司 Probiotics solid beverage capsule

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