CN215022729U - Capsule with three-layer structure - Google Patents

Capsule with three-layer structure Download PDF

Info

Publication number
CN215022729U
CN215022729U CN202023193911.0U CN202023193911U CN215022729U CN 215022729 U CN215022729 U CN 215022729U CN 202023193911 U CN202023193911 U CN 202023193911U CN 215022729 U CN215022729 U CN 215022729U
Authority
CN
China
Prior art keywords
capsule
shell
cap
capsule shell
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202023193911.0U
Other languages
Chinese (zh)
Inventor
赵鲁松
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Tailored Biolog Technology Co ltd
Original Assignee
Shanghai Tailored Biolog Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Tailored Biolog Technology Co ltd filed Critical Shanghai Tailored Biolog Technology Co ltd
Priority to CN202023193911.0U priority Critical patent/CN215022729U/en
Application granted granted Critical
Publication of CN215022729U publication Critical patent/CN215022729U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Abstract

The utility model discloses a capsule with three-layer structure, including the capsule body and capsule cap, the capsule body includes inner capsule shell and outer capsule shell, outer capsule shell cover is established at inner capsule shell outer lane, capsule cap tip card is gone into between inner capsule shell and the outer capsule shell, and its surface is connected with outer capsule shell, and the internal surface is connected with inner capsule shell, inner capsule shell inner space and capsule cap inner space link to each other and form the medicine storage chamber, inner capsule shell surface is equipped with the external screw thread with capsule cap junction, capsule cap internal surface is equipped with the internal thread with external screw thread fit; the capsule body and the outer ring of the capsule cap are also provided with shells, and sweet liquid is filled among the shells, the capsule body and the capsule cap. Through setting up the screw thread, can avoid the emergence of the phenomenon of droing between the capsule body and the capsule cap, also can improve the sealing performance of capsule structure, set up the shell at outermost layer simultaneously, even patient bites broken also can only contact sweet liquid, can not contact inside medicine.

Description

Capsule with three-layer structure
Technical Field
The utility model relates to a capsule especially relates to a capsule with three layer construction.
Background
The capsule shell is an egg-shaped hollow shell which is made of edible medicinal gelatin through fine treatment and auxiliary materials and is used for containing solid powder and particles. The capsule shell has good bioavailability, and can be dissolved rapidly, reliably and safely.
The encapsulated medicine is generally a powder or granules which is irritating to the esophagus and gastric mucosa, or a medicine which is bad in taste, easy to volatilize, easy to be decomposed by saliva in the oral cavity, and easy to be inhaled into the trachea. The medicines are filled into capsules, so that the medicine property of the medicines is protected from being damaged, and the digestive organs and the respiratory tract are protected. Removal of the capsule shell may result in loss of the drug, waste of the drug, and reduced efficacy. In addition, some drugs need to be dissolved and absorbed in the intestine, and the capsule protects the drug from gastric acid. The medicine is capsule prepared with special film forming material, such as gelatin, cellulose, polysaccharide, etc. and the capsule may be filled with medicine in powder or liquid form for easy swallowing.
The existing capsules are generally used by combining a capsule cap and a capsule body, and because the capsule cap and the capsule body are two independent parts, a gap is inevitably formed between the capsule body and the capsule cap, so that the sealing performance of the medicine in the capsule is not strict, the quality guarantee period is short, and meanwhile, if a patient carelessly bites the capsule cap or the capsule body when taking the capsule, the medicine in the capsule is easy to directly contact with the medicine in the capsule, so that the medicine is invalid on one hand, the taste of the medicine is not good on the other hand, and the poor experience is brought to the patient.
SUMMERY OF THE UTILITY MODEL
In view of the above-mentioned not enough that exists at present, the utility model provides a three layer construction's capsule sets up the screw thread through the junction at capsule cap and the capsule body, can avoid the emergence of the phenomenon of droing between the capsule body and the capsule cap, also can improve the sealing performance of capsule structure, avoids appearing leaking the powder problem, sets up the shell and fills sweet taste liquid at outmost simultaneously, even patient bites broken also only can contact sweet taste liquid, can not contact inside medicine.
In order to achieve the above object, the embodiments of the present invention adopt the following technical solutions:
a capsule with a three-layer structure comprises a capsule body and a capsule cap which are matched with each other, wherein the capsule body comprises an inner capsule shell and an outer capsule shell, the outer capsule shell is sleeved on the outer ring of the inner capsule shell, the end part of the capsule cap is clamped between the inner capsule shell and the outer capsule shell, the outer surface of the capsule body is connected with the outer capsule shell, the inner surface of the capsule body is connected with the inner capsule shell, the inner space of the inner capsule shell is connected with the inner space of the capsule cap to form a medicine storage cavity, an external thread is arranged at the joint of the outer surface of the inner capsule shell and the capsule cap, and an internal thread matched with the external thread is arranged on the inner surface of the capsule cap; the capsule body and the outer ring of the capsule cap are also provided with shells, and sweet liquid is filled among the shells, the capsule body and the capsule cap.
In accordance with one aspect of the present invention, the medicament is stored in a medicament storage chamber inside the capsule shell and the capsule cap.
According to the utility model discloses an aspect, capsule cap and interior capsule shell can reach the intensity of capsule structure through external screw thread and internal screw thread cooperation connection, avoid the emergence of the phenomenon of droing between the capsule body and the capsule cap, also can improve the sealing performance of capsule structure, avoid appearing leaking the powder problem.
According to the utility model discloses an aspect through outmost setting up the shell and filling sweet taste liquid, when patient bites open by accident, also can only contact the inside sweet taste liquid of shell, can not contact inside medicine, has ensured that the medicine can not become invalid, has improved user's the experience of taking medicine simultaneously.
According to one aspect of the present invention, the inner capsule shell comprises a porous acrylic resin layer, a chitosan layer and a gelatin layer from outside to inside.
According to an aspect of the utility model, most of medicines need to play a role in the intestinal tract, in order to prevent that it from appearing in advance in the stomach, have set up multilayer structure for inner capsule shell, ensure that it can appear in the intestinal tract.
According to the utility model discloses an aspect sets up porous acrylic resin and can make intestinal juice can get into inside the capsule shell through the pore acrylic resin layer to dissolve chitosan layer and gelatin layer gradually and reach the effect of release medicine.
According to one aspect of the present invention, the porous acrylic resin layer is provided with a plurality of closely arranged through holes.
According to one aspect of the utility model, still be provided with the pH buffer layer that forms by the preparation of magnesium hydroxide between porous acrylic resin layer and the chitosan layer.
According to an aspect of the present invention, the pH buffer layer is thicker than the porous acrylic resin layer, and the chitosan layer is thicker than the gelatin layer.
According to the utility model discloses an aspect, the setting can make the gastric acid in the gastric juice can not dissolve inner capsule shell by the pH buffer layer that magnesium hydroxide prepared forms, guarantees to get into and appears in the stomach again of the inside medicine of intestinal, leads to the phenomenon of medicine inefficacy.
In accordance with one aspect of the present invention, a gel is disposed between the inner capsule shell and the outer capsule shell.
According to an aspect of the present invention, the gel may improve the elasticity between the inner capsule shell and the outer capsule shell, avoiding crushing damage.
According to one aspect of the present invention, the outer surfaces of the outer capsule shell and the capsule cap are provided with a film coat.
According to an aspect of the utility model, the setting of membrane clothing can delay release, absorption, distribution, metabolism and the excretion process of inside medicine in vivo to reach the extension drug effect.
The utility model discloses the advantage of implementing: the utility model discloses a capsule with three-layer structure, the capsule with three-layer structure includes the capsule body and the capsule cap of mutually supporting, the capsule body includes inner capsule shell and outer capsule shell, outer capsule shell cover is established at inner capsule shell outer lane, the capsule cap tip card is gone into between inner capsule shell and the outer capsule shell, and its surface is connected with outer capsule shell, and the internal surface is connected with inner capsule shell, and inner capsule shell inner space and capsule cap inner space link to each other and form the medicine storage chamber, inner capsule shell surface is equipped with the external screw thread with capsule cap junction, capsule cap inner surface is equipped with the internal thread with the external screw thread fit; the capsule body and the outer ring of the capsule cap are also provided with shells, and sweet liquid is filled among the shells, the capsule body and the capsule cap. The thread is arranged at the joint of the capsule cap and the capsule body, so that the phenomenon of falling between the capsule body and the capsule cap can be avoided, the sealing performance of the capsule structure can be improved, the problem of powder leakage is avoided, and meanwhile, the shell is arranged at the outermost layer and is filled with the sweet liquid, so that the sweet liquid can only be contacted even if a patient bites the shell, and the medicine in the capsule can not be contacted.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a structural view of a capsule having a three-layer structure according to the present invention;
FIG. 2 is a structural view of an inner capsule shell of a capsule having a three-layer structure according to the present invention;
fig. 3 is a structural view of a porous acrylic resin layer of a capsule having a three-layer structure according to the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
As shown in fig. 1, 2 and 3, the capsule with a three-layer structure comprises a capsule body and a capsule cap 3 which are matched with each other, wherein the capsule body comprises an inner capsule shell 1 and an outer capsule shell 2, the outer capsule shell is sleeved on the outer ring of the inner capsule shell, the end part of the capsule cap is clamped between the inner capsule shell and the outer capsule shell, the outer surface of the capsule cap is connected with the outer capsule shell, the inner surface of the capsule cap is connected with the inner capsule shell, the inner space of the inner capsule shell is connected with the inner space of the capsule cap to form a medicine storage cavity 4, the joint of the outer surface of the inner capsule shell and the capsule cap is provided with an external thread 6, and the inner surface of the capsule cap is provided with an internal thread 7 matched with the external thread; the capsule body and the outer ring of the capsule cap are also provided with a shell 8, and sweet liquid 9 is filled between the shell and the capsule body as well as between the shell and the capsule cap.
In practical application, the medicine is stored in the medicine storage cavity inside the capsule shell and the capsule cap.
In practical application, the capsule shell, the capsule cap and the outer shell are made of edible medicinal gelatin through fine processing and auxiliary materials.
In practical application, the capsule cap and the inner capsule shell are connected in a matched mode through the external thread and the internal thread, so that the strength of the capsule structure can be improved, the phenomenon that a capsule body and the capsule cap fall off is avoided, the sealing performance of the capsule structure can be improved, and the powder leakage problem is avoided.
In practical application, through setting up the shell and filling sweet liquid at the outmost, when patient bites the damage by accident, also can only contact the inside sweet liquid of shell, can not contact inside medicine, ensured that the medicine can not become invalid, improved user's the experience of taking medicine simultaneously.
In practical application, the sweet taste liquid can be a solution dissolved with a sweetener, such as stevia sugar water.
In practical application, the inner capsule shell comprises a porous acrylic resin layer 12, a chitosan layer 13 and a gelatin layer 14 from outside to inside.
In practice, most drugs need to be effective in the intestine, and in order to prevent premature release in the stomach, the inner capsule shell is provided with a multilayer structure to ensure release in the intestine.
In practical application, the porous acrylic resin is arranged, so that intestinal juice can enter the inner capsule shell through the pore acrylic resin layer, and the chitosan layer and the gelatin layer are gradually dissolved to achieve the effect of releasing the medicine.
In practical application, the porous acrylic resin layer is provided with a plurality of through holes 15 which are closely arranged.
In practical application, a pH buffer layer 16 prepared from magnesium hydroxide is also arranged between the porous acrylic resin layer and the chitosan layer.
In practical application, the thickness of the pH buffer layer is larger than that of the porous acrylic resin layer, and the thickness of the chitosan layer is larger than that of the gelatin layer.
In practical application, the porous acrylic resin and the chitosan are both existing substances and can be directly purchased from the market.
In practical application, the pH buffer layer prepared from magnesium hydroxide can prevent gastric acid in gastric juice from dissolving the inner capsule shell, so that the drug to enter the intestinal tract can not be separated out from the stomach, and the drug is ineffective.
In practical application, a gel 5 is provided between the inner capsule shell and the outer capsule shell.
In practical application, the gel can improve the elasticity between the inner capsule shell and the outer capsule shell, and avoid extrusion damage.
In practical application, the gel belongs to a common substance, and related products can be directly purchased from the market.
In practical application, the outer surfaces of the outer capsule shell and the capsule cap are both provided with film coatings.
In practical application, the membrane coating can delay the release, absorption, distribution, metabolism and excretion processes of the internal medicine in vivo so as to achieve the effect of prolonging the medicine effect.
In practical application, the membrane coating belongs to the conventional arrangement of the capsule and can be realized by adopting the prior art.
The utility model discloses the advantage of implementing: the utility model discloses a capsule with three-layer structure, the capsule with three-layer structure includes the capsule body and the capsule cap of mutually supporting, the capsule body includes inner capsule shell and outer capsule shell, outer capsule shell cover is established at inner capsule shell outer lane, the capsule cap tip card is gone into between inner capsule shell and the outer capsule shell, and its surface is connected with outer capsule shell, and the internal surface is connected with inner capsule shell, and inner capsule shell inner space and capsule cap inner space link to each other and form the medicine storage chamber, inner capsule shell surface is equipped with the external screw thread with capsule cap junction, capsule cap inner surface is equipped with the internal thread with the external screw thread fit; the capsule body and the outer ring of the capsule cap are also provided with shells, and sweet liquid is filled among the shells, the capsule body and the capsule cap. The thread is arranged at the joint of the capsule cap and the capsule body, so that the phenomenon of falling between the capsule body and the capsule cap can be avoided, the sealing performance of the capsule structure can be improved, the problem of powder leakage is avoided, and meanwhile, the shell is arranged at the outermost layer and is filled with the sweet liquid, so that the sweet liquid can only be contacted even if a patient bites the shell, and the medicine in the capsule can not be contacted.
The above description is only for the specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are all covered by the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (7)

1. A capsule with a three-layer structure is characterized in that the capsule with the three-layer structure comprises a capsule body and a capsule cap which are matched with each other, the capsule body comprises an inner capsule shell and an outer capsule shell, the outer capsule shell is sleeved on the outer ring of the inner capsule shell, the end part of the capsule cap is clamped between the inner capsule shell and the outer capsule shell, the outer surface of the capsule cap is connected with the outer capsule shell, the inner surface of the capsule cap is connected with the inner capsule shell, the inner space of the inner capsule shell is connected with the inner space of the capsule cap to form a medicine storage cavity, an external thread is arranged at the joint of the outer surface of the inner capsule shell and the capsule cap, and an internal thread matched with the external thread is arranged on the inner surface of the capsule cap; the capsule body and the outer ring of the capsule cap are also provided with shells, and sweet liquid is filled among the shells, the capsule body and the capsule cap.
2. The capsule of claim 1, wherein the inner capsule shell comprises, from outside to inside, a porous acrylic resin layer, a chitosan layer, and a gelatin layer.
3. The capsule of claim 2, wherein the porous acrylic resin layer is provided with a plurality of through holes closely arranged.
4. The capsule of claim 3, wherein a pH buffer layer made of magnesium hydroxide is further disposed between the porous acrylic resin layer and the chitosan layer.
5. The capsule of claim 4, wherein the pH buffer layer is thicker than the porous acrylic resin layer and the chitosan layer is thicker than the gelatin layer.
6. Capsule with a three-layer structure according to claim 1, wherein a gel is provided between the inner and outer capsule shells.
7. The capsule of claim 1, wherein the outer capsule shell and the outer surface of the capsule cap are provided with a film coating.
CN202023193911.0U 2020-12-28 2020-12-28 Capsule with three-layer structure Active CN215022729U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202023193911.0U CN215022729U (en) 2020-12-28 2020-12-28 Capsule with three-layer structure

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202023193911.0U CN215022729U (en) 2020-12-28 2020-12-28 Capsule with three-layer structure

Publications (1)

Publication Number Publication Date
CN215022729U true CN215022729U (en) 2021-12-07

Family

ID=79222961

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202023193911.0U Active CN215022729U (en) 2020-12-28 2020-12-28 Capsule with three-layer structure

Country Status (1)

Country Link
CN (1) CN215022729U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114711364A (en) * 2022-04-14 2022-07-08 安徽善和生物科技有限公司 Probiotics solid beverage capsule

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114711364A (en) * 2022-04-14 2022-07-08 安徽善和生物科技有限公司 Probiotics solid beverage capsule

Similar Documents

Publication Publication Date Title
EP2263637B1 (en) Medicinal preparation for oral administration
KR0155563B1 (en) Large intestinal dissociative hard capsules
PT97369B (en) METHOD FOR PREPARING PHARMACEUTICAL FORMULATIONS IN WHICH THE FLAVOR OF THE MEDICINE AND DISFORCED BY MEANS OF COATING OF THE MEDICINE WITH A POLYMERIC MEMBRANE
JP2000516222A (en) Oral pharmaceutical composition that is easy to swallow
MXPA04002981A (en) Composite dosage forms.
Ubhe et al. A brief overview on tablet and it’s types
CN215022729U (en) Capsule with three-layer structure
WO1994004135A1 (en) Oral preparation for release in lower digestive tracts
CN208785315U (en) A kind of double-layer hollow capsule
JPH0729916B2 (en) Pharmaceutical composition having analgesic properties
CN107530294A (en) Enteric coated pellets containing proton pump inhibitor
HUT57578A (en) Process for producing tablet-capsule combination
CN100589793C (en) Pharmaceutical tablet system that floats on gastric fluid for multipulse release of active substance, the system and the preparation of the enveloping substance of the system
WO2006031584A2 (en) Quick dissolve medicament and method of manufacturing
CN219090322U (en) Double-effect capsule
CN101658482A (en) Low molecular chondroitin sulfate oral preparation, preparation method thereof and use thereof
CN219354715U (en) Hard capsule
CN213922376U (en) Capsule medicine taking bottle convenient to take medicine
CN113164405A (en) Hydroxypropyl methylcellulose hollow capsule
CN219517205U (en) Abnormal hollow capsule
CN219354688U (en) Hard capsule convenient to swallow
CN220293854U (en) Hard capsule with gastric mucosa protecting function
CN208065476U (en) A kind of medicinal oral hard capsule
CN206745635U (en) It is a kind of to be easy to the band carbohydrate gum capsule that children eat
CN219423337U (en) Capsule with medicine slow-release function

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant