CN208732989U - A kind of natural bioactive polypeptide and cell factor complex liquid preparation facilities - Google Patents
A kind of natural bioactive polypeptide and cell factor complex liquid preparation facilities Download PDFInfo
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- CN208732989U CN208732989U CN201821176758.0U CN201821176758U CN208732989U CN 208732989 U CN208732989 U CN 208732989U CN 201821176758 U CN201821176758 U CN 201821176758U CN 208732989 U CN208732989 U CN 208732989U
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- centrifuge tube
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Abstract
The utility model discloses a kind of natural bioactive polypeptides and cell factor complex liquid preparation facilities, including centrifuge tube and centrifuge body, thick tissue strainer pipe is equipped with inside centrifuge tube, catheter is equipped with inside thick tissue strainer pipe, sealing cover is equipped with above centrifuge tube, centrifuge body sidewall upper face is equipped with ball, it is divided into collecting chamber and motor cavity inside centrifuge body, collecting chamber lower left outer wall is equipped with collecting pipe, middle is equipped with motor inside motor cavity, transmission shaft is connected with above motor, transmission shaft penetrates bottom surface below collecting chamber, and it is fixedly connected with centrifuge tube bottom end, the present apparatus combines separation and purification in active peptides extraction process, so that being filtered separation in centrifugation, save extraction time, guarantee the activity of peptide material, and structure is detachable, convenient for cleaning, guarantee device cleaning, improve the work extracted The quality of property peptide material.
Description
Technical field
The utility model relates to biotech equipment field, specially a kind of natural bioactive polypeptide and cell factor are multiple
Close liquid preparation facilities.
Background technique
With the development of scientific and technical research, existing a large amount of abundant and multiple types have the function of triumph and life in organism
The active natural polypeptides of object and Porcine HGF are gradually exploited research, most of Porcine HGF of natural bioactive
Belong to polypeptide, active peptides have the characteristics that simpler than protein structure, molecular weight is smaller, biological effect is higher.At present
Science and technology can from people, animals and plants, microorganism and marine organisms etc. it is a variety of biology in extraction purification it is all kinds of out
Active peptides.It is isolated and purified in active extraction configuration, the separation method being often used is Ultra filtration membrane method, is surpassed
Filter membrane partition method is a kind of pressurization membrane separation technique, i.e., under pressure, small molecule solute and solvent can be perforated through centainly
The special film in hole, macromolecular solute is detained, to be isolated and purified.
Nowadays be mostly centrifugation apparatus using equipment used in Ultra filtration membrane method, by centrifugation apparatus to extracting solution into
Row centrifugation, separates, such separate mode needs to expend the supernatant liquor of extracting solution is put into ultrafiltration membrane separating device
Time can not keep the activity of peptide material well, and the device for separating and filtering is non-dismountable, is easy to make extracting solution
Some impurity residuals.
Utility model content
The purpose of this utility model is to provide a kind of natural bioactive polypeptide and cell factor complex liquid preparation facilities,
To solve the problems mentioned in the above background technology.
To achieve the above object, the utility model provides the following technical solutions: a kind of natural bioactive polypeptide and cell
Factor complex liquid preparation facilities, including centrifuge tube and centrifuge body, the centrifuge tube are cylindrical tube, and centrifuge tube is equipped with annulus
The connection ring of shape, connection ring lower end surface are provided with sliding slot, and connection ring upper surface is provided with circular limit card slot, in the centrifuge tube
Portion is equipped with thick tissue strainer pipe, thick that strainer pipe upper end-face edge is organized to be equipped with snap ring, and snap ring is fastened on the bottom surface of limit card slot,
Catheter is equipped with inside thick tissue strainer pipe, catheter upper end-face edge is equipped with snap ring, and snap ring is fastened on thick tissue strainer pipe
The card slot that end face is provided with, is equipped with sealing cover above the centrifuge tube, and the centrifuge body is cylindrical tube shape, centrifuge tube setting from
Heart internal body, centrifuge body sidewall upper face are equipped with ball, and the sliding slot that ball and connection ring lower end surface are provided with is cooperatively connected, from
Scheming internal body portion is collecting chamber and motor cavity, and collecting chamber lower left outer wall is equipped with collecting pipe, connects inside collecting pipe and collecting chamber
Logical, middle is equipped with motor inside motor cavity, and motor is fixedly connected with motor cavity bottom surface, is connected with biography above motor
Moving axis, transmission shaft penetrates bottom surface below collecting chamber, and is fixedly connected with centrifuge tube bottom end.
Preferably, the centrifugation inside pipe wall is equipped with ultrafiltration film layer, and the bottom end of centrifuge tube is inverted conical shape, thick to organize strainer pipe
Outer wall contact setting with the inner wall of centrifuge tube, the outer wall of the thick snap ring for organizing to be equipped with above strainer pipe and the inner wall of limit card slot
Cooperation contact, catheter upper end-face edge is equipped with the outer wall of snap ring and thick tissue strainer pipe upper end is provided with the inner wall of card slot with splice grafting
Touching.
Preferably, the upper surface of the thick tissue strainer pipe and the upper surface of catheter are in same level height, sealing cover
Lower section is equipped with cylindrical elastic packing block, and the inner wall of the outer wall for the elastic packing block being equipped with below sealing cover and limit card slot
It is tightly connected, the lower end surface for the elastic packing block being equipped with below sealing cover and the upper surface of thick tissue strainer pipe are in sealing contact.
Preferably, centrifuge body sidewall upper face is equipped with 36 balls, and 36 balls are along the axle center of centrifuge body
Around being uniformly arranged, the transmission shaft connected above motor is perforated through the junction below collecting chamber equipped with bearing, and bearing
Junction sealed set.
Preferably, the inside of the outer wall of the centrifuge tube and centrifuge body is there are the spacing of 2-3cm, the lower end of centrifuge tube with
There are 3-5cm spacing between centrifuge body inner bottom surface, collecting pipe is close to open up above collecting chamber bottom surface, catheter bottom end and thick
There are 1-2cm spacing between tissue strainer pipe inner bottom surface.
Compared with prior art, the utility model has the beneficial effects that
1. being centrifuged inside pipe wall is equipped with ultrafiltration film layer, for filtering macromolecular in extracting solution, to obtain the activity of small molecule
Polypeptide, centrifuge tube internal sleeve are equipped with thick tissue strainer pipe, for filtering the macroscopic tissue in extracting solution, in centrifuge body
Portion can collect the activity polypeptid substance that centrifuge tube filters out, the present apparatus combine separation in active peptides extraction process and
Purification saves extraction time, guarantees the activity of peptide material so that being filtered separation in centrifugation；
2. catheter casing is located inside thick tissue strainer pipe, thick that strainer pipe sleeve is organized to be located inside centrifuge tube, centrifuge shield
It is located inside centrifuge body, and structure is detachable, convenient for cleaning, guarantees device cleaning, improve the activity polypeptid substance of extraction
Quality.
Detailed description of the invention
FIG. 1 is a schematic structural view of the utility model；
Fig. 2 is the utility model structure front section view；
Fig. 3 is the enlarged drawing in Fig. 2 at A.
In figure: centrifuge tube 1, centrifuge body 2, connection ring 3, limit card slot 4, thick tissue strainer pipe 5, catheter 6, collecting chamber
7, motor cavity 8, motor 9, collecting pipe 10, ball 11, sealing cover 12.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Fig. 1-3 is please referred to, the utility model provides a kind of technical solution: a kind of natural bioactive polypeptide and cell factor
Complex liquid preparation facilities, including centrifuge tube 1 and centrifuge body 2, centrifuge tube 1 are cylindrical tube, and centrifuge tube 1 is equipped with circular
Connection ring 3,3 lower end surface of connection ring are provided with sliding slot, and 3 upper surface of connection ring is provided with circular limit card slot 4, inside centrifuge tube 1
It is thick that 5 upper end-face edge of strainer pipe is organized to be equipped with snap ring equipped with thick tissue strainer pipe 5, and snap ring is fastened on the bottom surface of limit card slot 4
On, thick to organize to be equipped with catheter 6 inside strainer pipe 5,6 upper end-face edge of catheter is equipped with snap ring, and snap ring is fastened on thick tissue filter
The card slot that 5 upper surface of network management is provided with is equipped with sealing cover 12 above centrifuge tube 1, and centrifuge body 2 is cylindrical tube shape, and centrifuge tube 1 is arranged
Inside centrifuge body 2,2 sidewall upper face of centrifuge body is equipped with ball 11, the sliding slot that ball 11 and 3 lower end surface of connection ring are provided with
It is cooperatively connected, collecting chamber 7 and motor cavity 8 is divided into inside centrifuge body 2,7 lower left outer wall of collecting chamber is equipped with collecting pipe 10, collects
It is connected to inside pipe 10 and collecting chamber 7,8 inside middle of motor cavity is equipped with motor 9, the fixed company of motor 9 and 8 bottom surface of motor cavity
It connects, transmission shaft is connected with above motor 9, transmission shaft penetrates 7 lower section bottom surface of collecting chamber, and fixes and connect with 1 bottom end of centrifuge tube
It connects.
1 inner wall of centrifuge tube is equipped with ultrafiltration film layer, and for filtering macromolecular substances in extracting solution, the bottom end of centrifuge tube 1 is to fall
Cone is conducive to the filter effect for improving extracting solution, and the thick outer wall for organizing strainer pipe 5 contacts setting with the inner wall of centrifuge tube 1,
The outer wall for the snap ring being equipped with above thick tissue strainer pipe 5 is contacted with the cooperation of the inner wall of limit card slot 4, makes slightly to organize when being centrifuged
Strainer pipe 5 does not occur to loosen collision inside centrifuge tube 1, guarantees the safety inside centrifuge tube 1, and 6 upper end-face edge of catheter is equipped with
The outer wall of snap ring is contacted with the inner wall cooperation that thick tissue 5 upper end of strainer pipe is provided with card slot, sends out catheter 6 not inside centrifuge tube
Raw collision；
The upper surface of thick tissue strainer pipe 5 and the upper surface of catheter 6 are equipped with below same level height, sealing cover 12
Cylindrical elastic packing block, and the outer wall for the elastic packing block being equipped with below sealing cover 12 and the inner wall of limit card slot 4 seal
Connection, guarantees when being centrifuged, extracting solution will not export above centrifuge tube 1 splash from, the elasticity that is equipped with below sealing cover 12
The lower end surface of sealing block and the upper surface of thick tissue strainer pipe 5 are in sealing contact, and sealing cover is made to press the upper end of thick tissue strainer pipe 5
The upper surface in face and catheter 6 guarantees the stability of thick tissue strainer pipe 5 and catheter 6；
2 sidewall upper face of centrifuge body is equipped with 36 balls 11, and 36 balls 11 are surround along the axle center of centrifuge body 2
Even setting makes centrifuge tube 1 in 2 inner rotation of centrifuge body, reduces resistance, and the transmission shaft connected above motor 9 is perforated through
The junction of 7 lower section of collecting chamber is equipped with bearing, realizes transmission shaft rotatably, and the junction sealed set of bearing, prevents
Filtered extracting solution enters in motor cavity 8 and motor 9 contacts；
There are the spacing of 2-3cm, the lower end of centrifuge tube 1 and centrifuge bodies for the inside of the outer wall of centrifuge tube 1 and centrifuge body 2
There are 3-5cm spacing between 2 inner bottom surfaces, guarantee not wear between centrifuge tube 1 and centrifuge body 2, collecting pipe 10 is close to
It is opened up above 7 bottom surface of collecting chamber, guarantees that filtered extracting solution can be collected, in 6 bottom end of catheter and thick tissue strainer pipe 5
There are 1-2cm spacing between portion bottom surface, and when toward addition extracting solution inside centrifuge tube 1, catheter 6 can be smoothly by extracting solution
It imports inside centrifuge tube 1, prevents extraction drop from splashing.
Working principle: when this practical work, the catheter 6 that the extracting solution of polypeptide is equipped with above centrifuge tube 1 is poured into, is led
Liquid pipe 6 is funnel-form, and extracting solution enters inside centrifuge tube 1 from the bottom end of catheter 6, after being added and being appropriate, sealing cover 12 is close
Big envelope is located at 1 upper opening of centrifuge tube, starts the motor 9 inside motor cavity 8, and motor 9 drives centrifuge tube 1 by rotation axis
Rotation centrifugation is carried out, the sliding slot sliding that the ball 11 that 2 sidewall upper face of centrifuge body is equipped with is provided with below connection ring 3, wherein
1 inner wall of centrifuge tube is equipped with ultrafiltration film layer, is used to filter extracting solution under centrifugal force, the active peptides of small molecule is made to be separated to centrifugation
Outside pipe 1, the outer wall of centrifuge tube 1 is equipped with the through-hole of dense distribution, makes the filtered extracting solution of ultrafiltration film layer through outside centrifuge tube 1
Wall, 1 internal sleeve of centrifuge tube are equipped with thick tissue strainer pipe 5, and thick tissue strainer pipe 5 is fine mesh, for filtering the group in extracting solution
Residue is knitted, the active peptides extracting solution after having the separation of centrifuge tube 1 enters inside centrifuge body 2, and by 2 left side lower section of centrifuge body
Collecting pipe 10 flow out, be collected, in this way be centrifuged and filtering combine, speed the time of extraction, guarantee the work of peptide material
Property；Separation needs to clean device when finishing, and successively takes out sealing cover 12, and catheter 6 and thick tissue strainer pipe 5 carry out outer
The other cleaning in portion can increase the cleaning of device, guarantee the quality for extracting active peptides.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (5)
1. a kind of natural bioactive polypeptide and cell factor complex liquid preparation facilities, including centrifuge tube (1) and centrifuge body
(2), it is characterised in that: the centrifuge tube (1) is cylindrical tube, and centrifuge tube (1) is equipped with circular connection ring (3), connection
Ring (3) lower end surface is provided with sliding slot, and connection ring (3) upper surface is provided with circular limit card slot (4), and the centrifuge tube (1) is internal
It is thick that strainer pipe (5) upper end-face edge is organized to be equipped with snap ring equipped with thick tissue strainer pipe (5), and snap ring is fastened on limit card slot (4)
On bottom surface, thick to organize to be equipped with catheter (6) inside strainer pipe (5), catheter (6) upper end-face edge is equipped with snap ring, and snap ring card is set
Sealing cover (12) are equipped with above the card slot that slightly tissue strainer pipe (5) upper surface is provided with, the centrifuge tube (1), the centrifuge
Body (2) is cylindrical tube shape, and centrifuge tube (1) setting is internal in centrifuge body (2), and centrifuge body (2) sidewall upper face is equipped with ball
(11), the sliding slot that ball (11) and connection ring (3) lower end surface are provided with is cooperatively connected, and is divided into collecting chamber (7) inside centrifuge body (2)
With motor cavity (8), collecting chamber (7) lower left outer wall is equipped with collecting pipe (10), is connected to inside collecting pipe (10) and collecting chamber (7),
The internal middle of motor cavity (8) is equipped with motor (9), and motor (9) is fixedly connected with motor cavity (8) bottom surface, on motor (9)
Side is connected with transmission shaft, and transmission shaft penetrates bottom surface below collecting chamber (7), and is fixedly connected with centrifuge tube (1) bottom end.
2. a kind of natural bioactive polypeptide according to claim 1 and cell factor complex liquid preparation facilities, feature
Be: centrifuge tube (1) inner wall is equipped with ultrafiltration film layer, and the bottom end of centrifuge tube (1) is inverted conical shape, thick to organize strainer pipe (5)
Outer wall contact setting with the inner wall of centrifuge tube (1), the outer wall and limit card slot of the thick snap ring for organizing to be equipped with above strainer pipe (5)
(4) inner wall cooperates contact, and catheter (6) upper end-face edge is equipped with the outer wall of snap ring and thick tissue strainer pipe (5) upper end is provided with card
The inner wall of slot cooperates contact.
3. a kind of natural bioactive polypeptide according to claim 1 and cell factor complex liquid preparation facilities, feature
Be: the upper surface of thick tissue strainer pipe (5) and the upper surface of catheter (6) are in same level height, sealing cover (12)
Lower section is equipped with cylindrical elastic packing block, and the outer wall and limit card slot of the elastic packing block being equipped with below sealing cover (12)
(4) inner wall is tightly connected, and the lower end surface for the elastic packing block being equipped with below sealing cover (12) is upper with thick tissue strainer pipe (5)
End face seal contact.
4. a kind of natural bioactive polypeptide according to claim 1 and cell factor complex liquid preparation facilities, feature
Be: centrifuge body (2) the sidewall upper face is equipped with 36 balls (11), and 36 balls (11) are along centrifuge body (2)
Around being uniformly arranged, the transmission shaft connected above motor (9) is perforated through the junction below collecting chamber (7) equipped with axis in axle center
It holds, and the junction sealed set of bearing.
5. a kind of natural bioactive polypeptide according to claim 1 and cell factor complex liquid preparation facilities, feature
Be: the inside of the outer wall of the centrifuge tube (1) and centrifuge body (2) there are the spacing of 2-3cm, the lower end of centrifuge tube (1) with
There are 3-5cm spacing between centrifuge body (2) inner bottom surface, collecting pipe (10) is close to open up above collecting chamber (7) bottom surface, drain
There are 1-2cm spacing between pipe (6) bottom end and thick tissue strainer pipe (5) inner bottom surface.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821176758.0U CN208732989U (en) | 2018-07-24 | 2018-07-24 | A kind of natural bioactive polypeptide and cell factor complex liquid preparation facilities |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821176758.0U CN208732989U (en) | 2018-07-24 | 2018-07-24 | A kind of natural bioactive polypeptide and cell factor complex liquid preparation facilities |
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| Publication Number | Publication Date |
|---|---|
| CN208732989U true CN208732989U (en) | 2019-04-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821176758.0U Active CN208732989U (en) | 2018-07-24 | 2018-07-24 | A kind of natural bioactive polypeptide and cell factor complex liquid preparation facilities |
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| CN (1) | CN208732989U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113462529A (en) * | 2020-03-31 | 2021-10-01 | 广州盛嘉生物科技有限公司 | Biological tissue treatment equipment |
-
2018
- 2018-07-24 CN CN201821176758.0U patent/CN208732989U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113462529A (en) * | 2020-03-31 | 2021-10-01 | 广州盛嘉生物科技有限公司 | Biological tissue treatment equipment |
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