CN208693266U - Miniature LED probe - Google Patents
Miniature LED probe Download PDFInfo
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- CN208693266U CN208693266U CN201820527126.8U CN201820527126U CN208693266U CN 208693266 U CN208693266 U CN 208693266U CN 201820527126 U CN201820527126 U CN 201820527126U CN 208693266 U CN208693266 U CN 208693266U
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Abstract
The utility model discloses a miniature LED probe. The micro LED probe comprises a probe head and a connecting part connected with the probe head; the probe head comprises an active panel, a driving circuit and a micro LED array; the driving circuit is integrated on the active panel and comprises a plurality of driving units which are arranged in an array manner, and the micro LED array is positioned on one side of the driving circuit, which is far away from the active panel and comprises a plurality of micro LEDs which are arranged in a matrix manner; the driving units correspond to the micro LEDs one by one, and each driving unit is used for driving the corresponding micro LED; the driving unit comprises an excitation subunit and a detection subunit, the excitation subunit is used for driving the corresponding micro LED to emit first visible light in an excitation stage, and the detection subunit is used for driving the micro LED to detect second visible light in a detection stage. The technical scheme of the utility model realize the direct stimulation and the monitoring to nerve cell, with the real-time formation of image of nerve cell's activity situation to obtain nerve cell's three-dimensional view effect.
Description
Technical field
The utility model embodiment is related to neural Clinics more particularly to a kind of miniature LED probe.
Background technique
Miniature nerve probe is the important tool for Neuscience.Nerve probe is mainly used for brain in medical domain at present
Disease, such as epilepsy, migraine, Alzheimer's disease, the neurological diseases such as dementia.In recent years, in microelectric technique and light heredity
It learns and continues to develop under perfect background, the research of nerve probe also achieves quickly progress and development.By by nerve probe
The different zones of brain are implanted into, to record and stimulate specific site in brain, thus allow for detection, the processing of cell grade
And explain neural deta, to help medical personnel to understand neurological disease in depth and make reasonable response.
However, existing nerve probe, although can be realized the stimulation and monitoring to brain nervous cell, needs pair
Brain is dissected, to observe the optical signal of the sending of the fluorescent material in nerve cell.It, can not will be refreshing in the case where not dissecting
Activity situation through cell intuitively shows in real time, so that medical personnel be hindered to further appreciate that neurological disease.
Utility model content
The utility model provides a kind of miniature LED probe, directly carries out stimulation and monitoring activity to nerve cell to realize,
It can be by the activity situation real time imagery of nerve cell without human dissection.
In a first aspect, the utility model embodiment provides a kind of miniature LED probe, which includes probe
Head and the interconnecting piece being connect with the probe；
The probe includes active panel, driving circuit and Minitype LED array；The driving circuit is integrated in described
On active panel, including multiple driving units being arranged in array, the Minitype LED array is located at the driving circuit far from institute
The side for stating active panel, including multiple miniature LED in matrix arrangement；The driving unit and the miniature LED mono- are a pair of
It answers, each driving unit is for driving the corresponding miniature LED；
The driving unit includes excitation subelement and detection subelement, and the excitation subelement is used to drive in excitation phase
The dynamic corresponding miniature LED issues the first visible light, and the detection subelement is used in the detection phase driving miniature LED inspection
Survey the second visible light；Wherein, second visible light issues under the excitation of first visible light visible for object under test
Light.
Specifically, the excitation subelement includes the first transistor, second transistor, third transistor and first capacitor；
The grid of the first transistor is electrically connected with the first control terminal of the excitation subelement, the first transistor
The first pole be electrically connected with the input terminal of the excitation subelement, the second pole of the first transistor and the second transistor
Grid and the first capacitor the first pole electrical connection；The second of first pole of the second transistor and the first capacitor
Pole is electrically connected with first voltage line, and the second pole of the second transistor is electrically connected with the anode of the miniature LED；It is described miniature
The cathode of LED is electrically connected with the first pole of the third transistor, the grid of the third transistor and the excitation subelement
The second control terminal electrical connection, the second pole ground connection；
The detection subelement includes the 4th transistor, the 5th transistor, first resistor and memory element；
The grid of 4th transistor and the 5th transistor third control terminal and the with the detection subelement respectively
The electrical connection of four control terminals, the first pole of the 4th transistor are electrically connected with second voltage line, the second pole and the first resistor
First end electrical connection, the second end of first resistor is electrically connected with the cathode of the miniature LED；First pole of the memory element
Anode and cathode with the second pole respectively at the miniature LED is electrically connected；The anode of the miniature LED and the 5th transistor
The first pole electrical connection, the 5th transistor the second pole ground connection.
Specifically, the memory element is the second capacitor.
Specifically, which further includes the first clad, and the first clad uniform thickness cladding is described miniature
Region of the LED probe in addition to the miniature LED.
Specifically, the material of first clad is Parylene Parylene C.
Alternatively, the miniature LED probe further includes the second clad and third clad, the second clad uniform thickness packet
Region of the probe in addition to the miniature LED is covered, the third clad uniform thickness coats the interconnecting piece.
Specifically, the size of the miniature LED is 5 μm.
Specifically, the probe with a thickness of 10 μm.
Specifically, which includes substrate, the substrate include the first sub-portion and the second sub-portion, described first
Sub-portion is the substrate of the active panel, and second sub-portion is the substrate of the interconnecting piece；The material of the substrate is flexibility
Material.
Specifically, the flexible material is Parylene C.
The technical solution of the utility model embodiment, by the way that active panel, driving circuit and miniature are arranged in probe
LED array, the fluorescent material for issuing miniature LED in the first visible light stimulus brain nervous cell in excitation phase issue second
Visible light issues the second visible light that visible light is issued with fluorescent material in detection phase miniature LED and matches, to make to detect
Subelement receives the second visible light that fluorescent material issues and the conversion for carrying out photosignal, and second that fluorescent material is issued can
It is light-exposed to be converted into electric signal, it is transmitted in external equipment and performs image display, to realize the direct stimulation to nerve cell
And monitoring, can be by the activity situation real time imagery of nerve cell in the case where dissecting human body.Further, since
Each miniature LED may be implemented by corresponding to driving unit independent control illumination effect to single or multiple nerve cells
Stimulation, and then obtain the 3-D view effect of nerve cell.
Detailed description of the invention
Fig. 1 is a kind of cross-sectional view of miniature LED probe provided by the embodiment of the utility model；
Fig. 2 is a kind of top view of miniature LED probe provided by the embodiment of the utility model；
Fig. 3 is a kind of structural schematic diagram of driving unit provided by the embodiment of the utility model；
Fig. 4 is a kind of structural schematic diagram of reading circuit provided by the embodiment of the utility model.
Specific embodiment
The utility model is described in further detail with reference to the accompanying drawings and examples.It is understood that herein
Described specific embodiment is used only for explaining the utility model, rather than the restriction to the utility model.It further needs exist for
It is bright, part relevant to the utility model is illustrated only for ease of description, in attached drawing rather than entire infrastructure.
Fig. 1 is a kind of cross-sectional view of miniature LED probe provided by the embodiment of the utility model, and Fig. 2 is that the utility model is real
A kind of top view of miniature LED probe of example offer is applied, the present embodiment is applicable to not observe human body progress when dissected intuitively
The scene of cellular activity situation.As depicted in figs. 1 and 2, which includes probe 100 and connect with probe 100
Interconnecting piece 200.Probe 100 includes active panel 110, driving circuit 120 and Minitype LED array 130；Driving circuit 120
It is integrated on active panel 110, including multiple driving units 121 being arranged in array, Minitype LED array 130 is located at driving electricity
Side of the road 120 far from active panel 110, including multiple miniature LED131 in matrix arrangement；Driving unit 121 with it is miniature
LED131 is corresponded, and each driving unit 121 is for driving corresponding miniature LED131.Driving unit 121 includes exciton list
Member and detection subelement, excitation subelement are used to issue the first visible light, detection in the corresponding miniature LED131 of excitation phase driving
Subelement is used to drive miniature LED131 to detect the second visible light in the detection phase；Wherein, the second visible light is that object under test exists
The visible light issued under the excitation of first visible light.
Specifically, the miniature LED in Minitype LED array 130 can arrange in matrix, including x row y column, share x × y
Miniature LED131, wherein x and y is the arbitrary integer more than or equal to 1, and x and y can be equal or unequal.It is corresponding
, driving circuit 120 may include x × y driving unit 121, each driving unit 121 respectively correspond one it is miniature
LED131.Illustratively, as shown in Fig. 2, Minitype LED array 130 includes the miniature LED131 of 5 × 5 array arrangements, driving electricity
Road 120 includes 5 × 5 driving units 121, each driving unit 121 respectively corresponds a miniature LED131, and each drives
Moving cell 121 drives its corresponding miniature LED131 to shine.Fig. 2 is only the explanation to Minitype LED array 130 illustratively,
Rather than limit, the line number and columns of Minitype LED array 130 are not limited to shown in Fig. 2.
Driving unit 121 is electrically connected with miniature LED131, illustratively, can realize Minitype LED array by pad 150
130 are electrically connected with driving unit 121 in driving circuit 120, and the drive sub-circuits in driving unit 121 are driven
Corresponding miniature LED131 shines.
Specifically, driving unit 121 include excitation subelement and detection subelement, excitation subelement with it is corresponding miniature
LED constitutes exciting loop, and under the driving of excitation subelement, forward conduction is may be implemented in miniature LED.Detect subelement with it is corresponding
Miniature LED constitute detection circuit, detection subelement driving under, miniature LED may be implemented reverse breakdown conducting.
Specifically, in the course of work of miniature LED probe, driving unit 121 can be divided into excitation phase and detection rank
Section.In excitation phase, excitation signal and first control signal outside excitation subelement reception, when first control signal is effective
When, excitation signal is acted on the anode of corresponding miniature LED by excitation subelement, and miniature LED is made to issue the first visible light.It needs
Illustrate, the wavelength for the first visible light that miniature LED is issued, which should be able to meet, makes object under test in human body cell (generally
Fluorescent material) luminous wavelength requirement.For example, the fluorescent material of cell is by wave-length coverage in 420mm- inside cerebral tissue
It shines after visible light stimulus within the scope of 450mm, then miniature LED is issued in excitation phase, Minitype LED array 130 first
The wave-length coverage of visible light is 420mm-450mm.Therefore, it after miniature LED issues the first visible light, stimulates inside cerebral tissue
The fluorescent material of cell issues the second visible light.In the present embodiment, the collection of miniature LED probe is carried out using active panel 110
At can control Minitype LED array 130 by active matrix driving mode and shine, Minitype LED array 130 can be by the at this time
Whether one control signal control excitation subelement, which acts on excitation signal on miniature LED, makes miniature LED issue the first visible light,
So as to realize to effective control of the fluorescent material stimulation in brain nervous cell, the prison to nerve cell activity is realized
It surveys.
In the detection phase, the second control signal outside detection subelement reception is visited when second control signal is effective
Survey subelement makes corresponding miniature LED reverse breakdown under the active matrix driving of active panel 110, and carries out luminous.Miniature LED hair
When the wavelength of second visible light of wavelength and the fluorescent material transmitting of light out matches, detection subelement receives fluorescent material
Second visible light of transmitting simultaneously converts thereof into electric signal, and stores to electric signal, passes through the company connecting with probe 100
Socket part 200 is sent in the equipment of big external brain, to form image in the device, reflects the moving type of nerve cell
Condition, to realize the direct stimulation and monitoring to nerve cell, can will be refreshing in the case where dissecting human body
Activity situation real time imagery through cell.
It should be noted that miniature LED shines in excitation phase and detection phase, and luminous wavelength can
Meet the wavelength requirement for making that fluorescent material is luminous in human body cell, and the wavelength for the second visible light for needing to issue with fluorescent material
Match, therefore, the wave-length coverage of the luminous excitation signal (for example, first visible light) of excitation fluorescent material, and detection are glimmering
(for example, light that miniature LED is issued in the detection phase) wave-length coverage of the detectable signal for the second visible light that stimulative substance issues, two
Person has the wavelength components of coincidence, and the wave-length coverage for keeping miniature LED luminous includes the wavelength components of above-mentioned coincidence, to make miniature
LED can excite fluorescent material to issue the second visible light and detect the second visible light of fluorescent material sending, so that micro-
Type LED plays the role of different in the different stages.
It should also be noted that, interconnecting piece 200 is electrically connected with the driving circuit 120 in probe 100, driving circuit 120
It can be electrically connected by interconnecting piece 200 with external equipment, realize and the power supply of driving circuit 120 is supplied, while needing to detect
The electric signal of subelement storage is sent to external equipment by interconnecting piece 200, so that it is formed image in external equipment, to see
Survey the activity situation of big intracerebral nerve cell.As shown in Fig. 2, interconnecting piece 200 includes multiple connecting pins 121, it to be used for probe 100
It is connect with external equipment.Specifically, interconnecting piece 200 includes that probe 100 is connected with external power source connecting pin 121, Neng Gouwei
Driving circuit 120 on probe 100 persistently provides power supply.In addition, driving unit 120 will detect son list by interconnecting piece 200
The electric signal transmission of member storage is to external equipment, and therefore, interconnecting piece 200 further includes the connecting pin 121 for transmitting signal.
Multiple driving units 121 of driving circuit 120 can respectively drive multiple miniature in Minitype LED array 130
LED131, and corresponding miniature LED131 can be independently driven mutually, therefore can arbitrarily select Minitype LED array 130
In any miniature LED131 shine, it is thin that single or multiple nerves may be implemented when stimulating the fluorescent material in brain nervous cell
The stimulation of born of the same parents, and then the 3-D view effect of available nerve cell.In addition, driving circuit 120 can pass through complementary metal
Oxide semiconductor (Complementary Metal Oxide Semiconductor, COMS) technique is integrated in active panel
On 110, the highly integrated one chip effect of driving circuit 120 and Minitype LED array 130 is realized.
In the processing procedure of miniature LED131, electrode can be removed LED gusts miniature by laser lift-off technique after manufacturing
The substrate of column 130, illustratively, substrate can be Sapphire Substrate.The strip operation of above-mentioned substrate to work as Minitype LED array
After miniature LED131 in 130 shines, the light that miniature LED131 is issued can be emitted directly toward cerebral tissue and avoid LED gusts miniature
Absorption of the substrate of column 130 to light, enables light source to be deep into inside cerebral tissue, to realize to glimmering inside cerebral tissue
The stimulation of stimulative substance makes fluorescent material shine.Wherein, the fluorescent material inside cerebral tissue can be has in itself into the cell
, it is also possible to artificially be put into cell.
Illustratively, miniature LED probe provided by the utility model can be used in transgenic mouse being tested, and utilize light
Genetics technology makes miniature LED probe as fluorescent material, and by light genetics technology in the ChR2 that transgenic mouse is expressed
It is inserted into transgenic mouse cerebral tissue, the ChR2 fluorescent material of specific cells in selected brain area domain is stimulated.Swashing
The hair stage, when the first visible light that Minitype LED array 130 issues under (passing through active matrix driving mode) driving of excitation subelement
Wavelength when reaching the excitation wavelength of fluorescent material ChR2, ChR2 fluorescent material, which will be excited, issues the second visible light；At this time
Into the detection phase, the wave for the light that Minitype LED array 130 issues under (passing through active matrix driving mode) driving of detection subelement
The wavelength of second visible light of the long sending that is excited with ChR2 fluorescent material matches, detection subelement reception ChR2 fluorescent material
Second visible light of transmitting, and the second visible light that ChR2 fluorescent material is emitted is converted to electric signal and stores, by with
The interconnecting piece 200 that probe 100 connects is sent in the equipment of big external brain, so that image is formed in a device, observation nerve
The activity situation of cell.Luminous, therefore miniature LED is carried out because excitation subelement and detection subelement share same miniature LED131
Probe can be detected periodically, in one cycle, be divided into excitation phase and detection phase, make miniature LED at times
Shine, and generate different effects.
The technical solution of the present embodiment, by the way that active panel, driving circuit and Minitype LED array are arranged in probe,
The fluorescent material for issuing miniature LED in the first visible light stimulus brain nervous cell in excitation phase issues the second visible light,
It issues the second visible light that visible light is issued with fluorescent material in the detection phase to match, to make to detect subelement reception fluorescence
The second visible light that fluorescent material issues is converted into telecommunications by the second visible light of substance sending and the conversion for carrying out photosignal
Number, it is transmitted in external equipment and performs image display, so that the direct stimulation and monitoring to nerve cell are realized, not to people
Body can be by the activity situation real time imagery of nerve cell in the case where being dissected.Further, since each miniature LED is by right
Driving unit independent control illumination effect is answered, therefore the stimulation to single or multiple nerve cells may be implemented, and then obtain mind
3-D view effect through cell.
Based on the above technical solution, Fig. 3 is a kind of structure of driving unit provided by the embodiment of the utility model
Schematic diagram.As shown in figure 3, excitation subelement includes the first transistor T1, second transistor T2, the electricity of third transistor T3 and first
Hold C1.
The grid of the first transistor T1 is electrically connected with the first control terminal ctrl1 of excitation subelement, the first transistor T1's
First pole be electrically connected with the input terminal in of excitation subelement, the second pole of the first transistor T1 and the grid of second transistor T2 and
The first pole of first capacitor C1 is electrically connected；The first pole of second transistor T2 and the second pole of first capacitor C1 and first voltage line
VDD1 electrical connection, the second pole of second transistor T2 is electrically connected with the anode of miniature LED；The cathode and third crystal of miniature LED
The first pole of T3 is electrically connected, and the grid of third transistor T3 is electrically connected with the second control terminal ctrl2 of excitation subelement, the second pole
Ground connection.
Detecting subelement includes the 4th transistor T4, the 5th transistor T5, first resistor R1 and memory element C.
The grid of 4th transistor T4 and the 5th transistor T5 the third control terminal ctrl3 and the with detection subelement respectively
Four control terminal ctrl4 electrical connection, the first pole of the 4th transistor T4 are electrically connected with second voltage line VDD2, the second pole and the first electricity
The first end a electrical connection of R1 is hindered, the second end b of first resistor R2 is electrically connected with the cathode of miniature LED；The first of memory element C
Pole e and the second pole f are electrically connected with the anode and cathode of miniature LED respectively；The first of the anode of miniature LED and the 5th transistor T5
Pole electrical connection, the second pole ground connection of the 5th transistor T5.
In excitation phase, the first control terminal ctrl1 and the second control terminal ctrl2 of subelement is excited to control the first transistor
T1 and third transistor T3 conducting, the first pole of the first transistor T1 receive the signal of the input terminal in input of excitation subelement,
It is transmitted to the grid of second transistor T2.When the signal of the input terminal in input of excitation subelement can make miniature LED issue the
When the signal of one visible light, then second transistor T2 conducting is controlled, to make the voltage-drop loading of first voltage line VDD1 miniature
On the anode of LED, under normal circumstances, the voltage of first voltage line VDD1 is greater than zero, and the cathode of miniature LED passes through third crystal
Pipe T3 ground connection, therefore, when second transistor T2 conducting, miniature LED issues the first visible light.The first of miniature LED sending can
The fluorescent material of cell issues the second visible light inside light-exposed stimulation cerebral tissue.
In the detection phase, the third control terminal ctrl3 and the 4th control terminal ctrl4 for detecting subelement control the 4th transistor
T4 and the 5th transistor T5 conducting, the 4th transistor T4 input the voltage of second voltage line VDD2, load by first resistor R1
It is grounded in the anode of the cathode of miniature LED, miniature LED by the 5th transistor T5.Miniature LED can be a kind of single-photon avalanche
Diode, under the action of extra electric field, the free carrier electrons and holes in miniature LED can float under the action of electric field
It moves, respectively to two electrode movements of miniature LED, forms photoelectric current on external loop in this way, generate certain pressure drop, to visit
Measure optical signal.Under normal circumstances, the voltage of second voltage line VDD2 is greater than zero, in the detection phase, miniature LED reverse breakdown,
What the photoelectric current that miniature LED is generated by optical signal can double is amplified, and applies miniature LED in the field of optical power
It closes.After detecting the second visible light that subelement reception fluorescent material issues, miniature LED absorbs the energy of the second visible light, will
Second visible light is converted into photoelectric current, forms electric signal, and will be in electric signal storage to memory element C.Further, it is stored in
Electric signal in memory element C can be transmitted to external equipment by the reading circuit being correspondingly arranged, which is formed in
Interconnecting piece.
Fig. 4 is a kind of structural schematic diagram of reading circuit provided by the embodiment of the utility model, reading circuit and detection
The both ends memory element C electrical connection in unit, reads the electric signal on memory element C.Reading circuit is using the parallel reading side of column
Formula, to accelerate the speed that reading circuit reads electric signal.
Illustratively, as shown in figure 3, memory element C can be the second capacitor C2.First resistor R1 connects with miniature LED,
When miniature LED reverse breakdown, current rush, first resistor R1 can play the role of current limliting at this time, so that circuit is from damage
Evil.
It should be noted that the voltage value of first voltage line VDD1 and second voltage line VDD2 and miniature LED shine it is bright
Spend related, and miniature LED luminous wavelength is related with the luminous launch wavelength of fluorescent material, therefore according to the transmitting of fluorescent material
Wavelength and the miniature suitable voltage value of LED parameter selection.
On the basis of above-mentioned each embodiment, miniature LED probe can also include the first clad, first clad etc.
Thickness coats region of the miniature LED probe in addition to miniature LED.
Specifically, the first clad can be with integral coating probe and interconnecting piece.First clad is biocompatibility
Material, makes miniature LED probe biocompatibility with higher and stronger affinity, and miniature LED probe can be in brain group
The free floating of middle holding is knitted, so as to be monitored to cell specific in selected brain area domain, and do not will cause very
Big injury.Illustratively, the material of the first clad is Parylene Parylene C.In addition, in miniature LED probe work
During work, the miniature LED in Minitype LED array is needed to carry out luminous, therefore, when the first clad coats miniature LED probe
It needs except miniature LED, to avoid blocking miniature LED to shine.
A kind of embodiment arranged side by side is that miniature LED probe may include the second clad and third with above-described embodiment
Clad, the second clad uniform thickness coat region of the probe in addition to miniature LED, and third clad uniform thickness coats interconnecting piece.
Specifically, the material of the second clad and third clad is the material of biocompatibility, can it is identical can also
With difference.The process for coating miniature LED probe can be divided into the progress of two steps, first be wrapped using the second clad to probe
Cover, cladding process is consistent with the process of miniature LED probe is coated using the first clad, need miniature LED is exposed outside,
It avoids blocking miniature LED to shine；Then interconnecting piece is coated using third clad.
It should be noted that carrying out integral coating to miniature LED probe using the first clad, or using the second cladding
Layer and third clad respectively coat probe and interconnecting piece, as long as the material of each clad is the material of biocompatibility
Material, so that it may which, so that miniature LED probe biocompatibility with higher and stronger affinity, miniature LED probe can be big
It keeps free in brain tissue to float, so as to be monitored to cell specific in selected brain area domain, and will not make
At very big injury.
On the basis of the various embodiments described above, the size of miniature LED can be 5 μm.The thickness of probe can be 10 μm.
Specifically, the smaller integrated level of the size of miniature LED is higher.In the present embodiment, the size of miniature LED is 5 μm,
Size and subcellular adjoining dimensions, therefore can integrate more miniature LED in the Minitype LED array of same size, thus
Realize the high-resolution of miniature LED probe.Equally, the thickness of probe is thinner, the biocompatibility of miniature LED probe and affine
Power is better.After the size for selecting miniature LED, the thickness of the first clad or the second clad and third clad is meeting
It is thin as far as possible after the biocompatibility and affinity of miniature LED probe, illustratively, probe with a thickness of 10 μm, can be with
Take into account the one-piece construction and higher biocompatibility and affinity of miniature LED probe.
On the basis of the various embodiments described above, miniature LED probe includes substrate, and substrate includes the first sub-portion and the second son
Portion, the first sub-portion are the substrate of active panel, and the second sub-portion is the substrate of interconnecting piece；The material of substrate is chosen as flexible material.
Specifically, substrate includes the first sub-portion as the substrate of active panel 110 and the substrate as interconnecting piece 200
Second sub-portion.As shown in Fig. 2, active panel 110 should be including the cabling in the first sub-portion and the first sub-portion of substrate (in figure not
It shows).Interconnecting piece 200 includes the second sub-portion of the connecting pin 201 and substrate drawn by the connecting line of probe 100.It is exemplary
Ground, the second sub-portion of substrate can be the extension of the first sub-portion.Connecting pin 201 and the lead-out wire being connect with connecting pin 201 printing
In the second sub-portion of substrate, fixed connection end 201 and the lead-out wire connecting with connecting pin 201, probe 100 pass through connecting pin
201 are electrically connected with external equipment realization.The probe 100 and interconnecting piece 200 of miniature LED probe share a substrate, Ke Yijian
Change structure.
In addition, substrate material can use flexible material, miniature LED probe is made to reduce the traction applied to cerebral tissue
Power increases biocompatibility and affinity, human body rejection is reduced, to increase the use scope of miniature LED probe.
Illustratively, the flexible material of active panel 110 be can be Parylene C.
Note that above are only the preferred embodiment and institute's application technology principle of the utility model.Those skilled in the art's meeting
Understand, the utility model is not limited to specific embodiment described here, is able to carry out for a person skilled in the art various bright
Aobvious variation, readjustment and substitution is without departing from the protection scope of the utility model.Therefore, although passing through above embodiments
The utility model is described in further detail, but the utility model is not limited only to above embodiments, is not departing from
It can also include more other equivalent embodiments in the case that the utility model is conceived, and the scope of the utility model is by appended
Scope of the claims determine.
Claims (10)
1. a kind of miniature LED probe, which is characterized in that including probe and the interconnecting piece being connect with the probe；
The probe includes active panel, driving circuit and Minitype LED array；The driving circuit is integrated in described active
On panel, including multiple driving units being arranged in array, the Minitype LED array is located at the driving circuit to be had far from described
The side of source panel, including multiple miniature LED in matrix arrangement；The driving unit and the miniature LED are corresponded, often
A driving unit is for driving the corresponding miniature LED；
The driving unit includes excitation subelement and detection subelement, and the excitation subelement is used in excitation phase driving pair
The miniature LED is answered to issue the first visible light, the detection subelement is used to detect the in the detection phase driving miniature LED
Two visible lights；Wherein, second visible light is the visible light that object under test issues under the excitation of first visible light.
2. miniature LED probe according to claim 1, which is characterized in that
The excitation subelement includes the first transistor, second transistor, third transistor and first capacitor；
The grid of the first transistor is electrically connected with the first control terminal of the excitation subelement, and the of the first transistor
One pole is electrically connected with the input terminal of the excitation subelement, the second pole of the first transistor and the grid of the second transistor
Pole and the electrical connection of the first pole of the first capacitor；First pole of the second transistor and the second pole of the first capacitor with
The electrical connection of first voltage line, the second pole of the second transistor is electrically connected with the anode of the miniature LED；The miniature LED
Cathode be electrically connected with the first pole of the third transistor, the of the grid of the third transistor and the excitation subelement
The electrical connection of two control terminals, the second pole ground connection；
The detection subelement includes the 4th transistor, the 5th transistor, first resistor and memory element；
Third control terminal and fourth of the grid of 4th transistor and the 5th transistor respectively with the detection subelement is controlled
End processed electrical connection, the first pole of the 4th transistor are electrically connected with second voltage line, and the of the second pole and the first resistor
One end electrical connection, the second end of the first resistor are electrically connected with the cathode of the miniature LED；First pole of the memory element
It is electrically connected respectively with the anode and cathode of the miniature LED with the second pole；The anode of the miniature LED and the 5th transistor
The first pole electrical connection, the 5th transistor the second pole ground connection.
3. miniature LED probe according to claim 2, which is characterized in that the memory element is the second capacitor.
4. miniature LED probe according to claim 1, which is characterized in that it further include the first clad, first cladding
Layer uniform thickness coats region of the miniature LED probe in addition to the miniature LED.
5. miniature LED probe according to claim 4, which is characterized in that the material of first clad is poly- to two
Toluene Parylene C.
6. miniature LED probe according to claim 1, which is characterized in that further include the second clad and third cladding
Layer, the second clad uniform thickness coat region of the probe in addition to the miniature LED, the third clad uniform thickness
Coat the interconnecting piece.
7. miniature LED probe according to claim 1, which is characterized in that the size of the miniature LED is 5 μm.
8. miniature LED probe according to claim 1, which is characterized in that the probe with a thickness of 10 μm.
9. miniature LED probe according to claim 1, which is characterized in that further include substrate, the substrate includes the first son
Portion and the second sub-portion, first sub-portion are the substrate of the active panel, and second sub-portion is the substrate of the interconnecting piece；
The material of the substrate is flexible material.
10. miniature LED probe according to claim 9, which is characterized in that the flexible material is Parylene C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820527126.8U CN208693266U (en) | 2018-04-13 | 2018-04-13 | Miniature LED probe |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820527126.8U CN208693266U (en) | 2018-04-13 | 2018-04-13 | Miniature LED probe |
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| CN208693266U true CN208693266U (en) | 2019-04-05 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108464818A (en) * | 2018-04-13 | 2018-08-31 | 南方科技大学 | miniature L ED probe |
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2018
- 2018-04-13 CN CN201820527126.8U patent/CN208693266U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108464818A (en) * | 2018-04-13 | 2018-08-31 | 南方科技大学 | miniature L ED probe |
| CN108464818B (en) * | 2018-04-13 | 2023-12-29 | 南方科技大学 | Miniature LED probe |
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