CN208654032U - A kind of spectrum detection device - Google Patents
A kind of spectrum detection device Download PDFInfo
- Publication number
- CN208654032U CN208654032U CN201821239725.6U CN201821239725U CN208654032U CN 208654032 U CN208654032 U CN 208654032U CN 201821239725 U CN201821239725 U CN 201821239725U CN 208654032 U CN208654032 U CN 208654032U
- Authority
- CN
- China
- Prior art keywords
- light
- optical path
- exciting
- entrance
- detection device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The utility model discloses a kind of spectrum detection device, clinical medical inspection technical field, including excitation light entrance, excitation light exit excite and form exciting light optical path between light entrance and excitation light exit；Visible light source entrance is additionally provided between excitation light entrance and excitation light exit, it is seen that visible light optical path is formed between radiant entrance and exciting light optical path, it is seen that light optical path and exciting light optical path vertical connection；The first light splitting piece with exciting light optical path in 45 ° of angles is provided at the position that visible light optical path is connected with exciting light optical path.Using when, exciting light in excitation light path issues fluorescence by reflection focusing illumination to detectable substance, the fluorescence is collected subsequently into exciting light optical path, but some stray lights can be mingled in fluorescence, the light of wavelength even is eliminated stray light by the principle of interference decrease of light as stray light in visible light source at this time, later after the filtering of third optical filter, fluorescence is transmitted from the first light splitting piece hence into photoelectric multiplier.
Description
Technical field
The utility model relates to clinical medical inspection technical fields, and in particular to a kind of spectrum detection device.
Background technique
Chemiluminescent labeling immunoassay is also known as chemiluminescence immune assay, be with the direct labelled antigen of chemiluminescent agent or
The immunoassay method of antibody.Chemical illumination immunity analysis instrument includes two parts, i.e. immune response system and chemiluminescence point
Analysis system.Chemiluminescence analysis system is the oxidation using catalysis and oxidant of the chemiluminescent substance through catalyst, forms one
The intermediate of a excitation state when this excitation state intermediate returns to stable ground state, while launching photon, using shine
Signal measurement apparatus measures quantum yield of luminscence.Immune response system be by luminescent substance (reactant excitation under generate excitation state
Intermediate) be marked directly on antigen (chemiluminescence immune assay) or antibody (immunochemiluminometry) or enzyme effect in
Luminous substrate.
Core sensitive detection parts are that photomultiplier tube (PMT) is examined by single photon when in use in chemical illumination immunity analysis instrument
Amplifier is surveyed and is transmitted to, and the Current amplifier that adds high pressure, analog current is converted digital current by amplifier, and digital current will be sent out
Optical signals R232 data line is transferred to computer and is calculated, and obtains clinical effectiveness.
Such as the patent of Patent No. 200410071057, excitation light source is reflected through the filtered light beam of optical filter through light splitting piece
After focus on detectable substance, then detectable substance generates fluorescence, which is collected into after phosphor collection optical path, focusing through filtering then
It is transferred to photoelectric multiplier, but the fluorescence can be mingled with certain stray light in phosphor collection optic path；Stray light is exactly
Receive the external disturbance light wave in light.
Summary of the invention
For deficiency existing for above-mentioned background technique, the utility model proposes a kind of spectrum detection devices, it is intended to solve
There are a large amount of astigmatism, the low problems of accuracy in detection for luminescent substance spectrum during prior art spectral detection.
In order to achieve the above object, the utility model mainly provides the following technical solutions:
A kind of spectrum detection device, including excitation light entrance, excitation light exit, excite between light entrance and excitation light exit
Form exciting light optical path；Visible light source entrance is additionally provided between the excitation light entrance and excitation light exit, it is seen that light light
Visible light optical path is formed between source inlet and exciting light optical path, it is seen that light optical path and exciting light optical path vertical connection；Visible light light
The first light splitting piece with exciting light optical path in 45 ° of angles is provided at the position that road is connected with exciting light optical path.
It the purpose of this utility model and solves its technical problem also following technical measures can be used to further realize.
Preferably, the visible light source inlet is provided with the first optical filter.
Preferably, the visible light source inlet is additionally provided with the protective cover for placing visible light source displacement.
Preferably, the material that the protective cover uses is rubber.
Preferably, the excitation light entrance is provided with the second optical filter；Excitation second optical filter of light entrance
Top edges are provided with the first light barrier for blocking environment stray light.
Preferably, the exciting light exit is provided with the second light barrier for blocking environment stray light；Second gear
The spring stop for preventing the second light barrier from falling off also is fixedly connected at tabula rasa.
Preferably, the exciting light optical path includes exciting light entrance and exciting light propagation segment, it is seen that light optical path and swash
The mutual level of entrance that shines is independently arranged, it is seen that light optical path and exciting light propagation segment vertical connection；Photomultiplier tube setting exists
On the axis direction of exciting light propagation segment；Fluorescence light path is formed between excitation light exit and photomultiplier tube；Fluorescence light path and swash
The optical path that shines is shared in exciting light propagation segment optical path；Exciting light entrance and fluorescence light path vertical connection；Fluorescence light path and excitation
The second light splitting piece with exciting light in 45 ° of angles is provided at the position that light entrance section is connected；First light splitting piece and second point
Condenser lens is provided between mating plate.
Preferably, the exit position of fluorescence light path is provided with third optical filter.
Preferably, being the right side with the direction of propagation of fluorescence light path, the right side edge of third optical filter is provided with for blocking
The third light barrier of environment stray light.
Preferably, the visible light source is LED light.
The utility model has the beneficial effects that exciting light entrance the utility model proposes a kind of spectrum detection device and swashing
Shine the visible light source entrance being additionally provided between exporting with exciting light optical path vertical connection；Visible light optical path and excitation light
The first light splitting piece with exciting light optical path in 45 ° of angles is provided at the position that road is connected, it is seen that radiant is sharp for eliminating
The stray light in fluorescence in the optical path that shines, to improve the accuracy of testing result.In application, the exciting light in excitation light path
By reflection focusing illumination to detectable substance to issue fluorescence, which is collected subsequently into exciting light optical path, but in fluorescence
Some stray lights can be mingled with, the light of wavelength is weakened or even disappeared by the principle of interference of light as stray light in visible light source at this time
Stray light is removed, later after the filtering of third optical filter, fluorescence is transmitted from the first light splitting piece hence into photoelectric multiplier
In.And visible light source and its remaining light pass through the first light splitting piece again and reflect exciting light optical path.
Detailed description of the invention
By reading the following detailed description of the preferred embodiment, various other advantages and benefits are common for this field
Technical staff will become clear.The drawings are only for the purpose of illustrating a preferred embodiment, and is not considered as practical to this
Novel limitation.And throughout the drawings, identical component is indicated with identical pa-rameter symbols.In the accompanying drawings:
Fig. 1 is the overall structure diagram of the utility model embodiment；
Fig. 2 is the side view of Fig. 1；
Fig. 3 be Fig. 2 along the sectional view of A-A.
Attached drawing summarizes: 1, shell 2, upper cover 3, excitation light exit 4, check ring 5,6, first points of the first light barrier
Mating plate 7, the first fixed mechanism 8, condenser lens 9, the second light splitting piece 10, the second fixed mechanism 11, third optical filter 12,
Third light barrier 13, light-emitting window 14, the second optical filter 15, the second light barrier 16, excitation light entrance 17, the first optical filter
18, protective cover 19, visible light source entrance.
Specific embodiment
It is the technical means and efficacy reaching predetermined purpose of utility model and being taken for the utility model is further described, with
Lower combination attached drawing and preferred embodiment, to according to the utility model proposes a kind of spectrum detection device, specific embodiment,
Structure, feature and its effect, detailed description is as follows.In the following description, different " embodiment " or " embodiment " refers to not
It must be the same embodiment.In addition, the special characteristic, structure or feature in one or more embodiments can be by any suitable form groups
It closes.
Embodiment
As shown in Figure 1-3, a kind of spectrum detection device of the utility model first choice embodiment, including excitation light entrance
16, light exit 3 is excited, excites and forms exciting light optical path between light entrance 16 and excitation light exit.
Exciting light optical path includes exciting light entrance and exciting light propagation segment, it is seen that light optical path 19 and exciting light entrance
Mutual level is independently arranged, it is seen that light optical path and exciting light propagation segment vertical connection；Photomultiplier tube setting is in excitation light propagation
On the axis direction of section；Fluorescence light path is formed between excitation light exit 3 and photomultiplier tube；Fluorescence light path and exciting light optical path
It is shared in exciting light propagation segment optical path；Exciting light entrance and fluorescence light path vertical connection；Fluorescence light path and exciting light entrance
The second light splitting piece 9 with exciting light in 45 ° of angles is provided at the position being connected；First light splitting piece 6 and the second light splitting piece 9
Between be provided with condenser lens 8.
Visible light source entrance 19 is additionally provided between excitation light entrance 16 and excitation light exit 3, it is seen that radiant entrance
Visible light optical path is formed between 19 and exciting light optical path, it is seen that light optical path and exciting light optical path vertical connection；Visible light optical path with
The first light splitting piece 6 with exciting light optical path in 45 ° of angles is provided at the position that exciting light optical path is connected.
The first optical filter 17 is provided at visible light source entrance 19；The upside of first optical filter 17 also place prevent it is visible
The protective cover 18 of radiant displacement；The material that protective cover uses is rubber.
The second optical filter 14 is provided at excitation light entrance 16；The top edges of excitation 16 second optical filter 14 of light entrance are set
It is equipped with the first light barrier 5 for blocking environment stray light.
The second light barrier 15 for blocking environment stray light is provided at excitation light exit 3；At second light barrier 15 also
It is fixedly connected with the spring stop for preventing the second light barrier from falling off.
The exit position of fluorescence light path is provided with third optical filter 11；It is the right side, third with the direction of propagation of fluorescence light path
The right side edge of optical filter 11 is provided with the third light barrier 12 for blocking environment stray light；In the present embodiment, it is seen that light
Light source is LED light.
In the present embodiment, which includes hollow shell 1 and covers the upper cover 2 on shell；In being arranged in shell 1
Empty the first fixed mechanism 7 and the second fixed mechanism 10, hollow structure form exciting light propagation segment, have and swash on shell 1
The visible light optical path and exciting light optical path of luminous propagation segment vertical connection.First fixed mechanism 7 is for being fixedly mounted the first light splitting
Piece 6 and condenser lens 8；Second fixed mechanism 10 is for installing the second light splitting piece 9.
The utility model proposes a kind of spectrum detection device, excite light entrance 16 and excitation light exit 3 between also set up
There is the visible light source entrance 19 with exciting light optical path vertical connection；At the position that visible light optical path is connected with exciting light optical path
It is provided with the first light splitting piece 6 with exciting light optical path in 45 ° of angles, it is seen that radiant is glimmering in exciting light optical path for eliminating
Stray light in light, to improve the accuracy of testing result.In application, the exciting light in excitation light path is by reflection focusing illumination
To detectable substance to issue fluorescence, which is collected subsequently into exciting light optical path, but can be mingled in fluorescence some spuious
Light, the principle of interference decrease that the light of wavelength passes through light as stray light in visible light source at this time even are eliminated a large amount of spuious
Light, later after the filtering of third optical filter, fluorescence is transmitted from the first light splitting piece hence into photoelectric multiplier.And it is visible
Light source and its remaining light pass through the first light splitting piece again and reflect exciting light optical path.
Although the preferred embodiment of the utility model has been described, those skilled in the art once knows substantially new
Newness concept, then additional changes and modifications can be made to these embodiments.So the following claims are intended to be interpreted as includes
Preferred embodiment and all change and modification for falling into the scope of the utility model.
Obviously, it is practical without departing from this can to carry out various modification and variations to the utility model by those skilled in the art
Novel spirit and scope.If in this way, these modifications and variations of the present invention belong to the utility model claims and
Within the scope of its equivalent technologies, then the utility model is also intended to include these modifications and variations.
Claims (10)
1. a kind of spectrum detection device, including excitation light entrance, excitation light exit, excite shape between light entrance and excitation light exit
At exciting light optical path；It is characterized in that, it is additionally provided with visible light source entrance between the excitation light entrance and excitation light exit,
Visible light optical path is formed between visible light source entrance and exciting light optical path, it is seen that light optical path and exciting light optical path vertical connection；
The first light splitting piece with exciting light optical path in 45 ° of angles is provided at the position that visible light optical path is connected with exciting light optical path.
2. spectrum detection device as described in claim 1, which is characterized in that the visible light source inlet is provided with first
Optical filter.
3. spectrum detection device as described in claim 1, which is characterized in that the visible light source inlet is additionally provided with use
In the protective cover for preventing visible light source to be displaced.
4. spectrum detection device as claimed in claim 3, which is characterized in that the material that the protective cover uses is rubber.
5. spectrum detection device as described in claim 1, which is characterized in that the excitation light entrance is provided with the second optical filtering
Piece；The top edges of excitation second optical filter of light entrance are provided with the first light barrier for blocking environment stray light.
6. spectrum detection device as described in claim 1, which is characterized in that the exciting light exit is provided with for blocking
Second light barrier of environment stray light；The spring catch for preventing the second light barrier from falling off also is fixedly connected at second light barrier
Plate.
7. spectrum detection device as described in claim 1, which is characterized in that the exciting light optical path includes exciting light entrance
With exciting light propagation segment, it is seen that light optical path is independently arranged with the mutual level of exciting light entrance, it is seen that light optical path and exciting light pass
Broadcast a section vertical connection；Photomultiplier tube is arranged on the axis direction of exciting light propagation segment；Excite light exit and photomultiplier tube
Between form fluorescence light path；Fluorescence light path and exciting light optical path are shared in exciting light propagation segment optical path；Exciting light entrance with it is glimmering
Light optical path vertical connection；Being provided at the position that fluorescence light path is connected with exciting light entrance with exciting light is in 45 ° of angles
Second light splitting piece；Condenser lens is provided between first light splitting piece and the second light splitting piece.
8. spectrum detection device as claimed in claim 7, which is characterized in that the exit position of fluorescence light path is provided with third
Optical filter.
9. spectrum detection device as claimed in claim 8, which is characterized in that take the direction of propagation of fluorescence light path as right, third
The right side edge of optical filter is provided with the third light barrier for blocking environment stray light.
10. spectrum detection device as described in any one of claims 1 to 9, which is characterized in that the visible light source is LED
Lamp.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821239725.6U CN208654032U (en) | 2018-08-02 | 2018-08-02 | A kind of spectrum detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821239725.6U CN208654032U (en) | 2018-08-02 | 2018-08-02 | A kind of spectrum detection device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208654032U true CN208654032U (en) | 2019-03-26 |
Family
ID=65787564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821239725.6U Active CN208654032U (en) | 2018-08-02 | 2018-08-02 | A kind of spectrum detection device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208654032U (en) |
-
2018
- 2018-08-02 CN CN201821239725.6U patent/CN208654032U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20210072141A1 (en) | Radiation Carrier and Use Thereof in an Optical Sensor | |
| JP2612641B2 (en) | Optical analysis method, device for use therein, and assay method | |
| CN101960293B (en) | Optical sensor for measuring emission light from an analyte | |
| CN107709975B (en) | Fluorescence detection method and system | |
| CN101592659A (en) | A kind of based on the test strip quantitative detection system and the method thereof that continue fluorescent-substance markers | |
| CN110308127A (en) | Can more fluorescence signals simultaneously detect optical assay device | |
| US9885661B2 (en) | Analyte detection method, fluorescence detection method, and fluorescence detection apparatus using same | |
| JP2009529134A (en) | Apparatus and method for measuring photoluminescence, absorbance, and diffraction of fine objects in a fluid | |
| CN109791103A (en) | Detection of particles is carried out using thin lens | |
| US20160011112A1 (en) | Sample Plate and Analyzing Method | |
| US4031399A (en) | Fluorometer | |
| US20210311037A1 (en) | Upconversion for microscopy | |
| EP2990781A1 (en) | Fluoroscence detection apparatus and fluoroscence detection method | |
| CN110243795A (en) | A kind of evanescent wave Two Colour Fluorescence all -fiber biosensor | |
| CN110514575A (en) | The decoding apparatus and method of quantum point coding microball | |
| US20130171623A1 (en) | Binding Assays Utilizing Time-Resolved Up-Converting Luminescence Detection | |
| CN112964688B (en) | Method for detecting gene chip hybridization result by total internal reflection | |
| US20150247806A1 (en) | Clam-shell luminometer | |
| CN208654032U (en) | A kind of spectrum detection device | |
| CN210803281U (en) | Special detection equipment for lateral flow immunochromatography based on near-infrared two-zone fluorescence imaging | |
| CN100443886C (en) | Array light-emitting diode induced fluorescent tester | |
| CN208902606U (en) | A kind of CCD spectrometer of dedicated luminescence generated by light spectral measurement | |
| JP4480130B2 (en) | Optical analyzer | |
| CN109030427A (en) | A kind of CCD spectrometer of dedicated luminescence generated by light spectral measurement | |
| CN205027755U (en) | Multi -functional determine module box on immunoassay appearance |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |