CN208626408U - A kind of nasal-cavity administration pipe of via intranasal application administration - Google Patents

A kind of nasal-cavity administration pipe of via intranasal application administration Download PDF

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Publication number
CN208626408U
CN208626408U CN201820354074.9U CN201820354074U CN208626408U CN 208626408 U CN208626408 U CN 208626408U CN 201820354074 U CN201820354074 U CN 201820354074U CN 208626408 U CN208626408 U CN 208626408U
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China
Prior art keywords
nasal
administration
cavity
pipe
delivery tube
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Active
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CN201820354074.9U
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Chinese (zh)
Inventor
姬广超
王晓明
郑佳威
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SHANGHAI ANGECON BIOTECHNOLOGY CO Ltd
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SHANGHAI ANGECON BIOTECHNOLOGY CO Ltd
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Abstract

The utility model discloses a kind of nasal-cavity administration pipes of via intranasal application administration, including the administration pipe fitting being connected to syringe and the delivery tube hose for delivering drugs to deep nasal cavity;One end of the delivery tube hose is connecting pin, and the connecting pin and delivery tube fittings are simultaneously integrally formed;The other end of the delivery tube hose is intervention end, and the intervention end round end structure is provided with dosing holes on the side wall for intervening end 2-4mm;From outside to inside, the diameter in section is gradually reduced the dosing holes.Technical solutions of the utility model have the advantages that the cell transplantation for entering central nervous system, and via intranasal application administration mode compares traditional traumatic administration mode, can mitigate patient suffering, reduce the damage of patient, to reduce the risk of patient;Nasal-cavity administration pipe can go deep into nasal cavity, and when administration can reduce drug loss, improve the efficiency of nasal-cavity administration;The internal diameter of nasal-cavity administration pipe is small, and drug loss is small, suitable for cell nasal-cavity administration and other need the drug of low dosage nasal-cavity administration.

Description

A kind of nasal-cavity administration pipe of via intranasal application administration
Technical field
The utility model relates to a kind of nasal-cavity administration pipe, specially a kind of nasal-cavity administration pipe of via intranasal application administration belongs to doctor Treat equipment technology field.
Background technique
Cell transplantation plays a significant role in neurodevelopment and reparation damaged nerve tissue.Cell transplantation is reparation and generation For the effective ways of injured cerebral tissue, partial loop and function can be rebuild, for treatment neurodegenerative disease and nervous centralis System injury disease has important clinical meaning.
Cell transplantation at present enters central nervous system, and there are mainly two types of modes: lumbar puncture subarachnoid injection and head Portion's drilling injection.The former wound is small, the time is short, therapeutic domain is extensive, but still has certain operation difficulty and risk;The latter is in head It pushes up and bores one to two apertures on skull, then transplant cells into brain tissue, operation difficulty and risk are larger.
Blood-brain barrier be drug through it is peripherally administered enter brain treatment central disease main bottleneck, especially treatment brain The cell products of disease.It is located at the neurogenic disease of brain for therapeutic purpose, head drilling injection is at high cost, has wound, side Method is cumbersome, has security risk.
Nasal cavity is the cell administration approach of more suitable brain diseases, but cell products are different from conventional medicament how It improves operational efficiency and administering effect is a significant challenge.
Utility model content
The purpose of this utility model is to provide for a kind of nasal-cavity administration pipe of via intranasal application administration, to solve the prior art The above problem.
A kind of nasal-cavity administration pipe of via intranasal application administration, it is characterised in that: including the administration pipe fitting that is connected to syringe and Deliver drugs to the delivery tube hose of deep nasal cavity;One end of the delivery tube hose be connecting pin, the connecting pin with Delivery tube fittings are simultaneously integrally formed;The other end of the delivery tube hose is intervention end, and the intervention end is round end Structure is provided with dosing holes on the side wall for intervening end 2-4mm;The dosing holes from outside to inside, the diameter in section by It is decrescence small.
The maximum diameter of the dosing holes is 0.1-6mm, preferably 3mm;Diameter is 0.1-3mm at minimum, excellent Choosing is 0.5mm.
The length of the delivery tube hose is 30-100mm, preferably 55mm;Outer diameter is 1-5mm, preferably 2mm;Internal diameter is 0.1-3mm, preferably 0.5mm.
The internal diameter of the administration pipe fitting is 4-6mm, preferably 4.5mm.
The nasal-cavity administration tube material is one kind of medical macromolecular materials, preferably medical polyurethane.
The nasal-cavity administration pipe hose answers surface smooth, slightly soft, stimulates nasal cavity small.
Can be set on the outer wall of the administration pipe fitting it is several play it is anti-skidding, reinforce and it is easy to use the effects of Transformation, be such as provided with convex stupefied.
Technical solutions of the utility model have the advantages that
1, for entering the cell transplantation of central nervous system, via intranasal application administration mode traumatic gives prescription compared to traditional Formula can mitigate patient suffering, reduce the damage of patient, to reduce the risk of patient;
2, nasal-cavity administration pipe can go deep into nasal cavity, and when administration can reduce drug loss, improve the efficiency of nasal-cavity administration;
3, the internal diameter of nasal-cavity administration pipe is small, and drug loss is small, suitable for cell nasal-cavity administration and other need low dosage The drug of nasal-cavity administration.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model;
Fig. 2 is the A-A of Fig. 1 to partial profile structure;
In figure, 1, administration pipe fitting 2, delivery tube hose 3, dosing holes.
Specific embodiment
The technical characterstic of the utility model is further described with specific embodiment with reference to the accompanying drawing.
A kind of nasal-cavity administration pipe of nasal-cavity administration as shown in Figure 1 including the administration pipe fitting 1 being connected to syringe and is incited somebody to action Drug is transported to the delivery tube hose 2 of deep nasal cavity;One end of the delivery tube hose 2 be connecting pin, the connecting pin with Administration pipe fitting 1 is connected to and is integrally formed;The other end of the delivery tube hose 2 is intervention end, the intervention end round end Structure is provided with dosing holes 3 on the side wall for intervening end 3mm;The dosing holes 3 from outside to inside, the diameter in section by It is decrescence small.
The maximum diameter of the dosing holes 3 is 3mm;Diameter is 0.5mm at minimum.
The length of the delivery tube hose 2 is 55mm;Outer diameter is 2mm;Internal diameter is 0.5mm.
The internal diameter of the administration pipe fitting 1 is 4.5mm.
The nasal-cavity administration tube material is the medical polyurethane of medical macromolecular materials.
The delivery tube hose 2 answers surface smooth, slightly soft, stimulates nasal cavity smaller;
Be provided on the outer wall of the administration pipe fitting 1 it is several play it is anti-skidding, reinforce and it is easy to use the effects of It is convex stupefied.
In use, opening nasal-cavity administration tube packaging;Administration pipe fitting is connected on syringe;By syringe inner cell or The schneiderian membrane area that other drugs are injected to enrichment olfactory nerve below deep nasal cavity sieve plate by transplanting hose;Operation is completed, and is taken out Nasal-cavity administration pipe.

Claims (11)

1. a kind of nasal-cavity administration pipe of via intranasal application administration, it is characterised in that: including the administration pipe fitting being connected to syringe and incite somebody to action Drug is transported to the delivery tube hose of deep nasal cavity;One end of the delivery tube hose be connecting pin, the connecting pin with give Pencil fittings are simultaneously integrally formed;The other end of the delivery tube hose is intervention end, and the intervention end is round end knot Structure is provided with dosing holes on the side wall for intervening end 2-4mm;From outside to inside, the diameter in section is gradually for the dosing holes Reduce.
2. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 1, it is characterised in that: the dosing holes Maximum diameter is 0.1-6mm;Diameter is 0.1-3mm at minimum.
3. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 2, it is characterised in that: the dosing holes Maximum diameter is 3mm;Diameter is 0.5mm at minimum.
4. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 1, it is characterised in that: the delivery tube is soft The length of pipe is 30-100mm;Outer diameter is 1-5mm, internal diameter 0.1-3mm.
5. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 4, it is characterised in that: the delivery tube is soft The length of pipe is 55mm;Outer diameter is 2mm;Internal diameter is 0.5mm.
6. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 1, it is characterised in that: the delivery tube connects The internal diameter of head is 4-6mm.
7. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 6, it is characterised in that: the delivery tube connects The internal diameter of head is 4.5mm.
8. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 1, it is characterised in that: the nasal-cavity administration Tube material is one kind of medical macromolecular materials.
9. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 8, it is characterised in that: the nasal-cavity administration Tube material is medical polyurethane.
10. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 1, it is characterised in that: the nasal cavity is given Pencil hose surface is smooth.
11. a kind of nasal-cavity administration pipe of via intranasal application administration according to claim 1, it is characterised in that: the delivery tube It is provided on the outer wall of connector convex stupefied.
CN201820354074.9U 2018-03-15 2018-03-15 A kind of nasal-cavity administration pipe of via intranasal application administration Active CN208626408U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820354074.9U CN208626408U (en) 2018-03-15 2018-03-15 A kind of nasal-cavity administration pipe of via intranasal application administration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820354074.9U CN208626408U (en) 2018-03-15 2018-03-15 A kind of nasal-cavity administration pipe of via intranasal application administration

Publications (1)

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CN208626408U true CN208626408U (en) 2019-03-22

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115317773A (en) * 2022-10-11 2022-11-11 纳索菲德(上海)制药技术有限公司 Device for instilling medicine into nasal cavity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115317773A (en) * 2022-10-11 2022-11-11 纳索菲德(上海)制药技术有限公司 Device for instilling medicine into nasal cavity

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