CN208598998U - A kind of Pulsed Electric Fields oncotherapy electrode - Google Patents
A kind of Pulsed Electric Fields oncotherapy electrode Download PDFInfo
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- CN208598998U CN208598998U CN201721537014.2U CN201721537014U CN208598998U CN 208598998 U CN208598998 U CN 208598998U CN 201721537014 U CN201721537014 U CN 201721537014U CN 208598998 U CN208598998 U CN 208598998U
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Abstract
The utility model relates to a kind of Pulsed Electric Fields oncotherapy electrodes, the oncotherapy electrode includes fixed disk, steering wheel, at least three metal puncture needles, the rear end cap setting tool of every metal puncture needle has grips, the metal connecting piece for being provided with injection mouth in cavity and being connect with metal puncture needle, the outer peripheral surface of every metal puncture needle is enclosed with insulating protective layer, and the front end of metal puncture needle is made to form exposed portion, exposed portion is provided with multiple medicine-pouring holes being connected to water passage, wherein puncture needle is fixed centered on a metal puncture needle, the fixed puncture needle in center sequentially passes through fixed disk and steering wheel, residual metallic puncture needle is then used as movable puncture needle, movable puncture needle is passed through from the puncture needle movable span on steering wheel respectively, the grips of movable puncture needle is movably arranged in respectively in the grips movable span in fixed disk.The Pulsed Electric Fields oncotherapy electrode of the utility model has the advantages that structure is simple, therapeutic effect is good, use cost is low and operating time is short.
Description
Technical field
The utility model relates to the field of medical instrument technology, and in particular to a kind of Pulsed Electric Fields oncotherapy electrode.
Background technique
Cancer is to threaten one of human health and the principal disease of life, according to the one of world's Union Against Cancer (UICC) publication
Item data shows: in 2008, worldwide cancer patient's number was 12,700,000, and wherein death toll is up to 7,600,000.Separately
Report display according to the investigation statistics of ministry of Health of China: between past 30 years, cancer mortality increases eighty per cant or more, at present cancer
Disease has become the number one killer of the important disease for leading to urban and rural residents' death and health.The report of the World Health Organization (WHO)
Announcement also indicates that: in the world, newly-increased cases of cancer and cancer death lead also will with annual 1% speed increase,
And the increasing velocity in developing countries such as China, Russia, India can be faster, it is contemplated that the year two thousand thirty, the whole world will increase 2700 newly
Ten thousand cases of cancer, the number for dying of cancer are up to 17,000,000 people.
The treatment method of cancer mainly has operative treatment, radiation treatment and chemotherapy etc. at present, but these traditional are controlled
Treatment means by factors such as its indication, contraindication and side effects due to being limited, so therapeutic effect is still not ideal enough, because
This, seeks the important topic that new cancer treatment method is always medical field and biomedical engineering field.
In recent years the study found that cell after electroporation effect occurs, with the raising and impulse action of pulse strength
The irreversible electrical breakdown of cell membrane will occur for the increase of time, cause membranolysis until cell death.Utilize this spy
Property, researcher proposes irreversible electroparacentesis therapy, irreversible as a kind of tumour ablation means of novel non-thermal effect
Electroporation therapy is that electric pulse is acted on cancerous tissue, makes cancer cell that irreversible electrical breakdown occur, thus destroys cancer
The life condition of disease cell has achieved the purpose that kill cancer cell.But existing puncture needle is passed through in same sleeve
More root puncture needles, due to being limited by sleeve diameter, the diameter of puncture needle is thinner, is easily damaged, and puncture needle is inserted into lesion
The depth accuracy of tissue is poor, and then therapeutic effect is made to have a greatly reduced quality.
Utility model content
The purpose of this utility model is to provide a kind of Pulsed Electric Fields oncotherapy electrodes, to solve existing puncture
Needle is easily damaged, and the poor problem of depth accuracy of puncture needle insertion pathological tissues.
To achieve the above object, the utility model provides a kind of Pulsed Electric Fields oncotherapy electrode, the steep-sided pulse electricity
Field oncotherapy electrode includes fixed disk, steering wheel, at least three front ends in cone-shaped metal puncture needle, the every metal
Puncture needle is internally provided with water passage, and the rear end cap setting tool of the every metal puncture needle has the grips of cavity, described
The injection mouth being connected to the water passage and the metal connecting piece connecting with the metal puncture needle are provided in cavity, often
The outer peripheral surface of metal puncture needle described in root is enclosed with insulating protective layer, and the front end of the metal puncture needle is made to form exposed portion,
The exposed portion is provided with multiple medicine-pouring holes being connected to the water passage, and the fixed disk is parallel with the steering wheel to be set
It sets, wherein fixing puncture needle centered on a metal puncture needle, the fixed puncture needle in the center sequentially passes through described solid
Price fixing and the steering wheel, the remaining metal puncture needle are then used as movable puncture needle, and the activity puncture needle is respectively from described
Puncture needle movable span on steering wheel passes through, and the grips of the activity puncture needle is movably arranged in the fixed disk respectively
On grips movable span in.
Preferably, at least one metal puncture needle in the remaining metal puncture needle is as the fixed puncture needle in periphery, institute
The fixed puncture needle in periphery is stated through the steering wheel, the grips of the fixed puncture needle rear end in the periphery is connect with fixed disk.
Preferably, a connector, the company is arranged in the middle part of the every fixed puncture needle of the movable puncture needle and periphery
One end of fitting is connect with the fixed puncture needle in the center, and the other end and the fixed puncture needle of the movable puncture needle or periphery connect
It connects.
Preferably, locating piece, the side of the fixed disk and steering wheel are set in the grips of each movable puncture needle
Edge is provided with multiple tooth sockets, and the locating piece is arranged in the tooth socket.
Preferably, scale is provided on the metal puncture needle.
Preferably, the length in the exposed portion of metal puncture needle front end is greater than 2cm.
Preferably, the medicine-pouring hole equidistant interval is arranged in the exposed portion of metal puncture needle front end.
Preferably, the cross section of the metal puncture needle is in circular ring shape.
Preferably, the outer diameter of the metal puncture needle is 0.15-1.5mm.
The utility model has the advantages that the Pulsed Electric Fields oncotherapy electrode of the utility model passes through metal puncture
Needle induces current into patient's diseased region, and liquid medicine is imported lesion by the water passage inside metal puncture needle, passes through electric shock
Medications and remedies treatment is in conjunction with tumour cell is killed, to achieve the purpose that cure tumour.The steep-sided pulse electricity of the utility model
Field oncotherapy electrode has the advantages that structure is simple, therapeutic effect is good, use cost is low and operating time is short.
Detailed description of the invention
Fig. 1 is the side structure schematic view of Pulsed Electric Fields oncotherapy electrode in the utility model embodiment 1.
Fig. 2 is the present invention looks up structural representation of Pulsed Electric Fields oncotherapy electrode in the utility model embodiment 1.
Fig. 3 is the overlooking structure diagram of Pulsed Electric Fields oncotherapy electrode in the utility model embodiment 1.
Specific embodiment
The following examples illustrate the utility model, but is not intended to limit the scope of the present invention.
Embodiment 1
As shown in Figure 1, 2, 3, which includes that fixed disk 7, steering wheel 8 and four metals are worn
The Pulsed Electric Fields oncotherapy electrode of pricker, the utility model induces current into patient's diseased region by metal puncture needle,
Liquid medicine is imported into lesion by the water passage inside metal puncture needle, is killed in conjunction with drug therapy by peb treatment swollen
Oncocyte, to achieve the purpose that cure tumour.The Pulsed Electric Fields oncotherapy electrode of the utility model have structure it is simple,
The advantage that therapeutic effect is good, use cost is low and operating time is short.
The front end of metal puncture needle is in cone-shaped, in order to which metal puncture needle is easily inserted into the diseased region of patient,
The inside of metal puncture needle is provided with water passage along its length direction, and the cross section of metal puncture needle is in circular ring shape, outside
Diameter is 0.15-1.5mm, and the outer diameter of metal puncture needle specifically obtains optimal value vertically with experimental result.Rake vein in the present embodiment
Electric field oncotherapy electrode is rushed due to not limited by outer sleeve, diameter can suitably increase, therefore, metal puncture in the present embodiment
The structural strength of needle is higher, and is hardly damaged.External one layer of the package of metal puncture needle makes metal puncture needle front end keep exposed
Insulating protective layer 11, insulating protective layer 11 is made of plastics, medical macromolecular materials, rubber or other materials, in this implementation
In example, the length in the exposed portion of metal puncture needle front end is 4cm, and the exposed portion of metal puncture needle front end is provided with multiple and mistake water
The medicine-pouring hole 12 of channel connection, the injection in order to make liquid medicine penetrate into the tissue of patient's diseased region different depth, in the present embodiment
12 equidistant interval of hole is arranged in the exposed portion of metal puncture needle front end.The front end fixing sleeve of grips 2 is set to metal puncture needle
Rear end, the rear end of grips 2 are provided with cavity, are provided with injection mouth and metal connecting piece 23 in cavity, on the side wall of grips 2
It is provided with the medicine-pouring port 17 being connected to injection mouth, injection mouth is connected to water passage, in use, medicine-pouring port 17 and liquid medicine are injected
Device is connected by pipeline, and the liquid medicine of liquid medicine syringe injection is flowed out from each medicine-pouring hole 12 by water passage, penetrates into patient
In the tissue of diseased region different depth.Metal connecting piece 23 is connect with metal puncture needle, by metal connecting piece 23 and high-tension pulse
Power supply is rushed to connect by conducting wire.Puncture needle 1 is wherein fixed centered on a metal puncture needle, a metal puncture needle is as outer
Fix puncture needle 3 week, remaining two metal puncture needles are then used as movable puncture needle 4.
Fixed disk 7 is disposed in parallel relation to one another with steering wheel 8, and fixed disk 7 and steering wheel 8 are circular plate structure, fixed disk 7
On be symmetrically arranged with two arc-shaped gripping member movable spans, the grips 2 of 4 rear end of the width of gripping member movable span and movable puncture needle
Outer diameter matching, likewise, being provided with two arc-shaped puncture needle movable spans 6, gripping member movable span and puncture needle on steering wheel 8
The position of movable span 6 corresponds.The fixed puncture needle 1 in center sequentially passes through the center of fixed disk 7 Yu steering wheel 8, two activities
Puncture needle 4 is passed through from the puncture needle movable span 6 on steering wheel 8 respectively, and the grips 2 of movable puncture needle 4 is movably blocked respectively
In 2 movable span of grips in fixed disk 7, the fixed puncture needle 3 in periphery runs through steering wheel 8, fixed 3 rear end of puncture needle in periphery
Grips 2 connect with fixed disk 7.
Further, in order to reinforce the structural strength of metal puncture needle, the fixed puncture needle of every movable puncture needle 4 and periphery
A connector 9 is arranged in 3 middle part, and one end of connector 9 is movably set in the middle part of the fixed puncture needle 1 in center, and the other end is set
It is equipped with the card slot 10 that cross section is in C font, the other end of connector 9 passes through 10 active card of card slot and is set to movable puncture needle 4 or outer
Week fixes the outer peripheral surface of puncture needle 3, and movable puncture needle 4 and periphery are fixed puncture needle 3 and center by connector 9 to realize
Connection between fixed puncture needle 1.
Further, locating piece 16 is set in the grips 2 of each movable puncture needle 4, locating piece 16 includes elastic portion 15
The all-wing aircraft portion 14 at 15 both ends of elastic portion is connected to two, elastic portion 15 has certain radian, to make it have certain
The junction in the elasticity of recovery original shape after deforming, elastic portion 15 and two all-wing aircraft portions 14 is respectively set one and dashes forward
The edge of rib, fixed disk 7 and steering wheel 8 is provided with multiple tooth sockets 11, by the way that lug, nib to be arranged in tooth socket 11, to keep living
Dynamic puncture needle 4 it is fixed and can not activity press two all-wing aircraft portions 14 with hand when needing the position of adjustment activity puncture needle 4, make
Elastic portion 15 deforms, and lug, nib leaves tooth socket 11, when movable 4 position of puncture needle is adjusted to predeterminated position, unclamps again two
All-wing aircraft portion 14, elastic portion 15 restore original shape, and lug, nib is arranged in tooth socket 11.
Embodiment 2
The present embodiment based on embodiment 1, the present embodiment difference from example 1 is that, in the present embodiment
Scale is provided on metal puncture needle, medical staff can intuitively observe metal puncture needle insertion patient's lesion according to scale
The depth of position, treats the tissue of diseased region different depth.
Working principle: first choice adjusts the position of two movable puncture needles 4, and the fixed puncture needle 1 in center, periphery fixation are worn
Pricker 3 and movable puncture needle 4 are inserted into the diseased region of patient, then center is fixed to the output of puncture needle 1 with high-voltage pulse power source
End is connected by conducting wire, and the input terminal of the fixed puncture needle 3 in periphery or movable puncture needle 4 and high-voltage pulse power source is connected by conducting wire
It connects, the hf and hv pulse electric current of high-voltage pulse power source output imports patient's diseased region, periphery by the fixed puncture needle 1 in center
Hf and hv pulse electric current is then imported the defeated of high-voltage pulse power source as loop electrode by fixed puncture needle 3 or movable puncture needle 4
Enter end, when hf and hv pulse electric current is when passing through patient's sick cell, hf and hv pulse electric current can destroy sick cell
Cell membrane, to sick cell be killed, due to having the fixed puncture needle 3 in periphery or movable puncture needle 4 as loop electrode, high frequency
Only office will not damage the healthy cell outside pathological tissues by diseased region high-voltage pulse current.At the same time, may be used also
Medicine is injected to the medicine-pouring port 17 of the fixed puncture needle 1 in center, the fixed puncture needle 3 in periphery and movable puncture needle 4 by liquid medicine syringe
Water flows out liquid medicine from each medicine-pouring hole, penetrates into the tissue of patient's diseased region different depth, is controlled by peb treatment and drug
It treats and combines, can more quickly kill tumour cell, improve therapeutic effect.
Although above having made detailed description to the utility model with generality explanation and specific embodiment,
On the basis of the utility model, it can be modified or is improved, this is apparent to those skilled in the art
's.Therefore, these modifications or improvements on the basis of without departing from the spirit of the present invention, belong to the utility model and want
Seek the range of protection.
Claims (9)
1. a kind of Pulsed Electric Fields oncotherapy electrode, the Pulsed Electric Fields oncotherapy electrode include fixed disk, steering wheel,
At least three front ends are in cone-shaped metal puncture needle, which is characterized in that every metal puncture needle was internally provided with
Aquaporin, the rear end cap setting tool of the every metal puncture needle have the grips of cavity, are provided in the cavity and the mistake
The injection mouth of aquaporin connection and the metal connecting piece that connect with the metal puncture needle, every metal puncture needle outside
Circumferential surface is enclosed with insulating protective layer, and the front end of the metal puncture needle is made to form exposed portion, and the exposed portion is provided with multiple
The medicine-pouring hole being connected to the water passage, the fixed disk are arranged in parallel with the steering wheel, wherein a metal is worn
Puncture needle is fixed centered on pricker, the fixed puncture needle in the center sequentially passes through the fixed disk and the steering wheel, remaining
The metal puncture needle is then used as movable puncture needle, and the activity puncture needle is respectively from the puncture needle movable span on the steering wheel
It passes through, the grips of the activity puncture needle is movably arranged in respectively in the grips movable span in the fixed disk.
2. Pulsed Electric Fields oncotherapy electrode according to claim 1, which is characterized in that the remaining metal puncture needle
In at least one metal puncture needle as the fixed puncture needle in periphery, the fixed puncture needle in the periphery runs through the steering wheel, institute
The grips for stating the fixed puncture needle rear end in periphery is connect with fixed disk.
3. Pulsed Electric Fields oncotherapy electrode according to claim 2, which is characterized in that the every movable puncture needle
One connector is set with the middle part of the fixed puncture needle in periphery, the fixed puncture needle in one end of the connector and the center connects
It connects, the other end is connect with the fixed puncture needle of the movable puncture needle or periphery.
4. Pulsed Electric Fields oncotherapy electrode according to claim 3, which is characterized in that each movable puncture needle
Grips on locating piece is set, the edge of the fixed disk and steering wheel is provided with multiple tooth sockets, and the locating piece is arranged in
In the tooth socket.
5. Pulsed Electric Fields oncotherapy electrode according to claim 1, which is characterized in that set on the metal puncture needle
It is equipped with scale.
6. Pulsed Electric Fields oncotherapy electrode according to claim 2, which is characterized in that metal puncture needle front end
Exposed portion length be greater than 2cm.
7. Pulsed Electric Fields oncotherapy electrode according to claim 1, which is characterized in that the medicine-pouring hole equidistant interval
It is arranged in the exposed portion of metal puncture needle front end.
8. Pulsed Electric Fields oncotherapy electrode according to claim 1, which is characterized in that the cross of the metal puncture needle
Section is in circular ring shape.
9. Pulsed Electric Fields oncotherapy electrode according to claim 1, which is characterized in that outside the metal puncture needle
Diameter is 0.15-1.5mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721537014.2U CN208598998U (en) | 2017-11-16 | 2017-11-16 | A kind of Pulsed Electric Fields oncotherapy electrode |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721537014.2U CN208598998U (en) | 2017-11-16 | 2017-11-16 | A kind of Pulsed Electric Fields oncotherapy electrode |
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| Publication Number | Publication Date |
|---|---|
| CN208598998U true CN208598998U (en) | 2019-03-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721537014.2U Active CN208598998U (en) | 2017-11-16 | 2017-11-16 | A kind of Pulsed Electric Fields oncotherapy electrode |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107802955A (en) * | 2017-11-16 | 2018-03-16 | 中国人民解放军火箭军总医院 | A kind of Pulsed Electric Fields oncotherapy electrode |
-
2017
- 2017-11-16 CN CN201721537014.2U patent/CN208598998U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107802955A (en) * | 2017-11-16 | 2018-03-16 | 中国人民解放军火箭军总医院 | A kind of Pulsed Electric Fields oncotherapy electrode |
| CN107802955B (en) * | 2017-11-16 | 2024-03-22 | 中国人民解放军火箭军总医院 | Steep pulse electric field tumor treatment electrode |
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