CN208547613U - A kind of collection and detection device of sample - Google Patents

Abstract

The utility model relates to a kind of collection and detection devices of sample, the cavity including collecting sample, include the structure and flow-guiding structure for receiving and squeezing collecting part in the cavity.Also, the structure for receiving and squeezing collecting part includes the platform of the protrusion positioned at cavity bottom and the fence for being enclosed in platform surrounding, and there are three openings for tool on fence；Flow-guiding structure includes three drainage troughs of fence open bottom.The Sample Maximal amount that there is the collection and detection device of the sample of the utility model collection structure and flow-guiding structure, the sample that the maximum amount of can be collected on collecting part, and guarantee to be collected into is transmitted on detecting instrument.To solve the problems, such as that traditional detection device sample when big flux detects is inadequate, the detection of more analysis ingredients is realized especially suitable for a kind of sample.The sample collection detection device can sufficiently collect sample and make on the arrival detecting element for the Sample Maximal amount collected, to realize the detection of big flux.

Description

A kind of collection and detection device of sample

Technical field

The utility model belongs to medical diagnosis class article technical field, is related to a kind of for testing and analyzing the receipts of the sample of object Collect detection device.

Background technique

Quick diagnosis technology (POCT) is an important development direction of clinical examination.Immunochromatography be common technology it One, after the fine particles such as colloidal gold, dye emulsion particle label, by the way that association reaction, intuitive display detection knot is immunized Fruit.Immunochromatography is mainly used in the detection such as the quick diagnosis of disease, early pregnancy detection, drug abuse surveillance, tumor marker, exempts from Epidemic disease chromatography diagnosis has easy to operate, and the reaction time is short, testing result intuitively easy interpretation, and sample source is convenient, and testing cost is low, The advantages that not needing special installation is suitable for a large amount of screenings extensively, family's detection and road boundary detection.

The sample that Fast Detection Technique relies on is usually urine, blood, saliva, throat swab etc..Wherein urine capture is convenient, No pain, but may relate to adulterated problem, it is often right especially for drug or the detection of drug abuse, subject Testing result, which has, resists psychology, and the acquisition of urine specimen often further relates to privacy, and adulterated problem is difficult to avoid completely.Blood Detection sample collection has pain, and has the infection risk of denier, needs in the laboratory collecting sample for having academic expertise, generally It is not suitable for checking for the screening of a wide range of crowd and roadside.The sampling of throat swab sample is difficult, needs professional to operate, needle To certain detections, the sample needs of acquisition are cultivated under certain aseptic condition or specific environment, are not suitable for roadside inspection equally It surveys.And it is directed to saliva sample, have acquisition convenient, painless safe, subject can be in collecting sample under monitoring, and sample adulteration can Energy property is smaller.But there is also certain difficulties for the acquisition of saliva sample: subject, especially with regard to drug abuse surveillance by Examination person, due to largely taking drugs, saliva amount is less；Simultaneously as the resisting psychology of subject, is often unwilling to match Tester is closed, collecting sample is insufficient, leads to detection unsuccessfully etc..

On the other hand, the product of Fast Detection Technique provides several larger possibility often for a certain big target of detection The test strip of existing substance.Such as in drug abuse surveillance, for common drug species, it may detect big Fiber crops, cocaine, heroin, morphine, amphetamine, methamphetamine (meth), opium etc..But with the development of science and technology, Drugs suck situation and are also changing, and also can between different regions, not agnate, different living habits or even Different Individual There are the differences that drugs use type and metabolic condition.In addition, drugs are sucked, there is also a variety of drugs the case where being used in combination, Detection difficulty is caused to further increase.It is accurate to ensure to detect, the detection as much as possible for different material and needle should be provided The detection of a variety of metabolisable forms of substance is used to high frequency.4 kinds of substances/of detection or generation are only capable of since same test strips are generally up to about It thanks to object, and there is cross reaction between many metabolins or target substance, therefore, detection device needs to provide appearance as much as possible Receive the spaces of test strips.In addition to this, due to detecting many kinds of substance and/or metabolisable form simultaneously, the naked eyes used are read, by hand The mode of operation of record testing result becomes unable to meet demand, especially in the roadside on-site test for drunk driving, driving with poison etc., It needs detection device to be able to cooperate small handheld reading equipment, reads rapidly and record and analyze more under the conditions ofs light is bad equal Item testing result.

To sum up, current saliva detection device has many advantages, such as that sampling is objective, and it is painless to be not easy adulterated and sampling, but also deposits It is few in the object that detection device can detect simultaneously, need original naked eyes to read, hand-kept is unable to satisfy road boundary detection Etc. big flux detection requirement the problem of.Accordingly, it is desirable to provide one kind can accommodate more test strips simultaneously, and it can be suitably used for machine Device reads the detection device of analysis.

Utility model content

The utility model provides a kind of collection and detection device of new sample, the collection and detection device tool of the new sample There are collection structure and flow-guiding structure, the sample that the maximum amount of can be collected on collecting part, and guarantee the sample being collected into It is the maximum amount of to be transmitted on detecting instrument.To solve, traditional detection device sample when big flux detects is inadequate to be asked Topic, the detection of more analysis ingredients is realized especially suitable for a kind of sample.

Specifically, the collection and detection device of a kind of sample provided by the utility model, the cavity including collecting sample, In, it include the structure and flow-guiding structure for receiving and squeezing collecting part in the cavity.

In some preferred embodiments, the structure for receiving and squeezing collecting part includes positioned at the raised of cavity bottom Platform and the fence for being enclosed in platform surrounding.

In some preferred embodiments, the height of the fence is less than or equal to the length of collecting part.One specific In embodiment, the upper surface of platform is circle, and the circular surface size is identical as the bottom surface size of collecting part.

There are one or more openings in some preferred embodiments, on the fence.Opening is extruded for discharging Liquid sample out.

In some preferred embodiments, flow-guiding structure includes the drainage trough of fence open bottom.

In some preferred embodiments, there is groove on the platform.The groove is used in sample by platform and fence The sample storage that the space of formation is flowed out after squeezing, the secondary-confirmation for pattern detection.

In some preferred embodiments, the cavity is triangulo column structure；The cavity cross section is triangle knot Structure.

In some preferred embodiments, cavity is positive triangulo column structure；The cavity cross section is equilateral triangle knot Structure.

In some preferred embodiments, the flow-guiding structure includes the slope surface positioned at platform lateral wall.More specifically, Slope surface is located at the platform lateral wall of fence opening.In the utility model, the setting of slope surface makes platform be higher than drainage trough.

In some preferred embodiments, the drainage trough is three, and three side walls and bottom for being located at cavity connect Meet place；Drainage trough is located at the lower section of slope surface.More specifically, drainage trough also is located at the lower section of fence opening.Some preferred realities It applies in mode, the fence upper opening is three, and opening is corresponded with drainage trough；Each aperture position, which corresponds to be located at, each to be drawn Chute middle position.

In some preferred embodiments, the collection and detection device of the sample further includes detecting element, the detection member The sample reception region of part is positioned partially or entirely in drainage trough.

In some preferred embodiments, the cavity is isoceles triangle column structure；The cavity cross section is isosceles Triangular structure；The described isosceles triangle bottom edge length is greater than or equal to the length of waist edge.

In some preferred embodiments, the cavity has a straight line side wall, remaining is arc or other shapes Side wall.

In some preferred embodiments, the drainage trough is located at bottom edge side wall or straight line side wall and the cavity bottom of cavity Portion junction.

In some preferred embodiments, the fence opening is two；There are two notches for the drainage trough tool.It is described to enclose Column opening respectively corresponds drainage trough different location, contracts for discharging the liquid sample collected in collecting part, two fence openings Short liquid sample flow path reduces sample loss.

In some preferred embodiments, there is flow-guiding channel between the fence opening and drainage trough notch.

In some preferred embodiments, the cavity is circular cylindrical cavity, is connected at the one side wall of circular cylindrical cavity There is test chamber.

In some preferred embodiments, the test chamber is cuboid structure.

In some preferred embodiments, drainage trough is located at test chamber bottom, is enclosed by test chamber side wall and bottom.

There is an opening in some preferred embodiments, on the fence；One end of fence upper opening and drainage trough Connection.

In some preferred embodiments, which further includes lid, and cover cap, which merges to be sealed in, collects sample Cavity.

Beneficial effect

The sample collection detection device of the utility model can sufficiently collect sample and make the arrival for the Sample Maximal amount collected On detecting element, to realize the detection of big flux.

Detailed description of the invention

Fig. 1 is the schematic top plan view of the cavity of the collection and detection device of a sample of the utility model；

Fig. 2 is the sectional view of the cavity of the collection and detection device of sample shown in FIG. 1；

Fig. 3 is the schematic top plan view of another cavity of the collection and detection device of the utility model sample；

Fig. 4 is the schematic top plan view of the third cavity of the collection and detection device of the utility model sample；

Fig. 5 is the schematic internal view of the 4th kind of cavity of the collection and detection device of the utility model sample；

Fig. 6 is the schematic diagram of the collection detection sample device comprising Fig. 5 inside cavity structure.

Appended drawing reference

Collect the cavity 100 of detection sample, platform 110, fence 120, opening 130, drainage trough 140, slope surface 150, water conservancy diversion Channel 160, notch 141, test chamber 170, bottom edge/straight line side wall 101, isosceles avris wall 102, curved wall 103, lid 180, groove 111

Specific embodiment

In the following detailed description, the subsidiary reference word of legend is a part here, it is to illustrate this Utility model can the mode of actable specific concrete scheme illustrate.The utility model, which is not precluded, in we can also carry out it Its concrete scheme and the structure for changing the utility model without prejudice to the use scope of the utility model.

In the utility model, a kind of collection and detection device of sample is provided, which is used to collect sample, and detection should The content of analyte in sample.It is often necessary to detect the content of multiple analytes in sample simultaneously.Specifically, the sample This collection and detection device includes the cavity and detecting element for collecting sample, includes the structure for receiving and squeezing collecting part in cavity And flow-guiding structure.In use, the sample on collecting part is collected by the way that the structure of collecting part is received and squeezed in cavity, It is flowed on detecting element and is detected by flow-guiding structure again.The sample collection detection device of the utility model is received because having And the structure and flow-guiding structure of collecting part are squeezed, enable sample to be collected into cavity from collecting part by the maximum amount of In, then by the water conservancy diversion of flow-guiding structure, make the sample being collected into is more as far as possible to flow on detecting element, so as to effective Detection is completed, avoiding in some detections leads to the case where detecting failure because sample size is very few.Especially for utilize saliva Sample consumes illegal drugs and (usually to detect a variety of drug ingredients) detection detect drug addict, and effect is improved significant.

As shown in Figures 1 to 5, the receiving that is usually located in cavity 100 and the structure for squeezing collecting part include being located at chamber The platform 110 of the protrusion of body bottom and the fence 120 for being enclosed in platform surrounding.The platform 110 of the protrusion is fixed on cavity 100 Bottom, the side wall apart from cavity have a certain distance.The upper surface of platform 110 is used to contact and receive the bottom of collecting part Portion, therefore the upper surface shapes and sizes of platform 110 are identical as the bottom of collecting part.In one specific embodiment, collect Component is cylindrical structure, is corresponded, and the upper surface of platform 110 is circle.It is enclosed in the height of the fence 120 of platform surrounding Degree is less than or equal to the length of collecting part.More specifically, the height of fence 120 is less than or equal to the 2/3 of the length of collecting part. In some more specifically embodiments, 120 height of fence is between 5mm-15mm, it is preferred that 120 height of fence is in 8mm-12mm Between, more preferably, 120 height of fence is 8mm, 9mm, 10mm, 11mm, 12mm.Fence 120 and platform 110 are enclosed One space, after the space is for receiving collecting part, collecting part to be inserted into cavity 100, into the space, collecting part bottom Portion is contacted with 110 bottom of platform, and the side wall of collecting part is contacted with fence 120, after applying pressure on collecting part, collection portion Part is squeezed in the space that fence 120 and platform 110 are enclosed by platform 110 and fence 120, to make to be located at collecting part On liquid sample squeeze outflow.

Same to have one or more openings 130 on fence 120 as shown in Figures 1 to 5, these openings 130 make to be squeezed The space that the sample outflow fence 120 and platform 110 of extrusion are enclosed.The setting of opening 130 is to drain sample Onto detecting element, setting will lead to sample too much and be dispersed, and especially for the higher sample of this kind of viscosity of saliva, flow through The more generation wall built-up phenomenons of distance seriously cause sample to be collected reductions, and setting will lead to collection efficiency very little and reduce, Huo Zhehui Cause the sample size touched between multiple detecting elements uneven, to make part detection that cannot complete.Usually opening 130 is 1-3, it is preferred that be 1,2 or 3.

In the utility model, flow-guiding structure includes drainage trough 140 within the cavity.The drainage trough 140 for receive from The liquid sample of 130 outflow of fence opening, and be assigned sample and be flowed on detecting element.In some specific embodiments, The sample reception region of detecting element is contacted with drainage trough 140 or the sample reception region of detecting element is located at drainage trough 140 In, thus, liquid sample is flowed on the sample reception region of detecting element in drainage trough 140, completes detection.It connects for convenience Sample is received, drainage trough 140 is located at the bottom or lower section of fence opening 130.

Fig. 1 and Fig. 2 provides a kind of 100 schematic diagram of cavity of collection and detection device, which is triangulo column knot Structure, i.e. cavity cross section are triangular structure, and more specifically, cavity cross section is positive triangular structure.It is received in this type In the cavity 100 for collecting detection device, raised platform 110 is located at the center position of bottom in cavity 100, table on platform 110 Face is circle, in the raised fence 120 of 110 upper surface surrounding of platform.There is slope surface 150, the slope in the side wall of platform 110 The design in face 150 is more convenient liquid and smoothly flows.The lower section of slope surface 150 is equipped with drainage trough 140.Specifically, drainage trough 140 Side wall and cavity bottom junction in three equal lengths of cavity 100, are similarly three drainage troughs 140.These three drainages It is interconnected between slot 140.There are three the equally tools of fence upper opening 130, corresponds with three drainage troughs 140, i.e., one is opened Mouth 130 is located at the top of a drainage trough 140, and more specifically, the position of each opening 130 is corresponding to be located at each drainage trough 140 middle positions.After sample is extruded in the space that platform 110 and fence 120 are formed, flowed out from opening 130, it is suitable Opening 130 lower section slope surface 150 flow down, reach drainage trough 140 in.This way it is ensured that sample flow path rule and Distance is short as far as possible, so as to avoid the waste that wall built-up of the sample in flow process generates, so as to make sample quilts more as far as possible Detecting element absorbs.In some embodiments, flow-guiding channel, the water conservancy diversion can also be set in slope surface upper railings opening corresponding position One end of the channel connects fence opening, and the other end is located on drainage trough, and liquid sample in fence opening is facilitated to flow into along flow-guiding channel Into drainage trough, guarantee the short path flowing of sample, so that the maximum amount of make the sample being collected into reach drainage trough for detecting.

In addition, as depicted in figs. 1 and 2, groove 111 is additionally provided on platform, which is located at Platform center, which makees For sample storage chamber, sample is stored, is checked for testing result.Squeezed in collecting part by the space that platform and fence enclose In the process, sample is flowed out from collecting part, and a part flows out along three fence openings and then reaches drainage trough and testing element Contact is detected, and another part sample is flowed into the groove on platform, is stored, the review for testing result and two Secondary confirmation.

As shown in figure 3,100 schematic diagram of cavity of another collection and detection device, cavity 100 are similarly triangulo column knot Structure, i.e. cavity cross section are triangle.The difference is that a side edge 101 of the triangular structure of such cavity 100 compares Long, other two side 102 is more relatively short.In such collection and detection device, usually will test element be arranged in it is longer At the side wall 101 on one side.Preferably, cavity is isoceles triangle column structure, i.e., cavity cross section is isosceles triangular structure.Its In, 101 length of isosceles triangle bottom edge is greater than the length of waist edge 102.In the collection and detection device of this type, in cavity 100 Receiving and squeeze the structure of collecting part, i.e., raised platform 110 and be enclosed in the fence 120 of platform surrounding and be similarly positioned in chamber The bottom of body 100, platform 110 and fence 120 form space to accommodate collecting part and collect the sample in the collecting part.Draw Chute 140 is located at 101 side wall of bottom edge and 100 bottom junctions of cavity of cavity, as shown in figure 3, drainage trough 140 is one.This When, opening 130 on fence is two, be connected with flow-guiding channel 160 at this two openings 130, flow-guiding channel 160 it is another One end is connected to and in communication with drainage trough 140.Specifically, on drainage trough 140 tool there are two notch 141, two flow-guiding channels 160 The other end is connect with two notches 141 on drainage trough respectively.After sample is flowed out from fence upper opening 130, it is logical to reach water conservancy diversion Road 160, then be flowed into drainage trough 140 by flow-guiding channel 160, it contacts and is detected with detecting element.The collection of the type It is equally the distance for keeping sample short as far as possible and defined route to reach detecting element, so as to be collected into detection device The maximum amount of sample guarantees going on smoothly for detection.

In other embodiments, 100 shape of cavity of collection and detection device are as follows: the side for guaranteeing a side wall is linear type, Namely the side wall is flatness, for one or more detecting elements to be arranged；Remaining sidewall sections shape is unlimited, such as circular arc Shape, ellipse arc, irregular shape etc..In Fig. 4, a part of side wall of cavity 100 is linear planar 101, remaining side wall is Arc 103.In the cavity 100, the intracorporal receiving of chamber and the structure for squeezing collecting part, i.e. raised platform 110 and enclosing It is similarly positioned in the bottom of cavity 100 in the fence of platform surrounding, platform 110 and fence form space to accommodate collecting part and receipts Collect the sample in the collecting part.Drainage trough 140 is located at line style side wall and the cavity bottom junction of cavity, as shown in figure 4, drawing Chute 140 is one.At this point, the opening 130 being located on fence is two, flow-guiding channel is connected at this two openings 130 160, the other end and the drainage trough 140 of flow-guiding channel 160 are connected to and in communication with.Specifically, there are two notches for tool on drainage trough 140 141, two notches, 141 drainage trough 140, the other end of two flow-guiding channels 160 respectively with two notches on drainage trough 140 141 connections.After sample is flowed out from fence upper opening 130, flow-guiding channel 160 is reached, then be flowed into and draw by flow-guiding channel 160 In chute 130, contacts and detected with detecting element.In the collection and detection device of the type, equally make sample short as far as possible Distance and defined route reach detecting element, so as to be collected into the maximum amount of sample, guarantee going on smoothly for detection.

As shown in fig. 6, the sample collection detection device of the utility model also has another structure, cavity 100 and detection Chamber 170 is connected to and in communication with, wherein and test chamber is connected at the one side wall of cavity, and test chamber is cuboid structure, specifically, Structure in long strip is extended out along cavity 100.It is covered with lid 180 on cavity 100, arrives cavity when the lid of lid 180 closes After on 100, cavity 100 is sealed with test chamber 170.Specifically, cavity is cylinder, as shown in figure 5, bottom within the cavity The platform 110 of the protrusion in portion and the fence 120 for being enclosed in platform surrounding are located at 100 bottom of cavity, and drainage trough 140 is located at test chamber 170 bottom has an opening 130 on fence 120, and fence upper opening 130 is connect with one end of drainage trough 140, even if also Cavity 100 and 170 liquid communication of test chamber.When collecting part is received in the space that platform 110 and fence 120 are formed and collects sample After this, sample is flowed into the contact of the detecting element in drainage trough 140 namely in test chamber 170, in test chamber 170 along opening 130 Sample is detected.In this sample collection detection device, fence opening 130 is directly connect with drainage trough 140, is directly saved Sample flow path all arrives in drainage trough so that sample be made not to be wasted, and ensure that the sample size that detection needs.

Claims (10)

1. a kind of collection and detection device of sample, the cavity including collecting sample, which is characterized in that include receiving in the cavity And squeeze the structure and flow-guiding structure of collecting part.

2. the collection and detection device of sample according to claim 1, which is characterized in that receive and squeeze the knot of collecting part Structure includes the platform of the protrusion positioned at cavity bottom and the fence for being enclosed in platform surrounding.

3. the collection and detection device of sample according to claim 2, which is characterized in that have one or more on the fence A opening.

4. the collection and detection device of sample according to claim 3, which is characterized in that flow-guiding structure includes fence open bottom The drainage trough in portion.

5. the collection and detection device of sample according to claim 4, which is characterized in that the cavity is triangulo column knot Structure；The cavity cross section is triangular structure.

6. the collection and detection device of sample according to claim 5, which is characterized in that cavity is positive triangulo column structure； The cavity cross section is positive triangular structure.

7. the collection and detection device of sample according to claim 6, which is characterized in that the flow-guiding structure further includes being located at The slope surface of platform lateral wall.

8. the collection and detection device of sample according to claim 7, which is characterized in that the drainage trough is three, respectively Positioned at three side walls and bottom junctions of cavity；The drainage trough is located at the lower section of slope surface.

9. the collection and detection device of sample according to claim 8, which is characterized in that the fence upper opening is three, Opening is corresponded with drainage trough；Each aperture position is corresponding to be located at each drainage trough middle position.

10. the collection and detection device of sample according to claim 8, which is characterized in that the sample collection detection device It further include detecting element, the sample reception region of the detecting element is positioned partially or entirely in drainage trough.