CN208547572U - A kind of compatible colorimetric, than turbid and fluorescence detection optical system - Google Patents
A kind of compatible colorimetric, than turbid and fluorescence detection optical system Download PDFInfo
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- CN208547572U CN208547572U CN201820720922.3U CN201820720922U CN208547572U CN 208547572 U CN208547572 U CN 208547572U CN 201820720922 U CN201820720922 U CN 201820720922U CN 208547572 U CN208547572 U CN 208547572U
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- turbid
- fluorescence detection
- reaction cup
- light
- colorimetric
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Abstract
The utility model relates to optical analysis detection technique field, a kind of compatible colorimetric is referred specifically to, than turbid and fluorescence detection optical system；Including radiation source, reaction cup and colorimetric spectral module, radiation source and colorimetric spectral module are respectively arranged at left and right sides of reaction cup, and optical filter wheel is equipped between radiation source and reaction cup, and optical filter wheel is equipped with light hole and several optical filters；Refractive light paths on front side of the reaction cup are equipped with than turbid and fluorescence detection module；The utility model is structurally reasonable, it will be arranged in the refractive light paths vertical with the transmission direction of reaction cup than turbid fluorescent moieties, colorimetric is corresponded to, than turbid and fluorescence detection by rotating filtering piece wheel, lesser light hole reduces the influence of amount of reagent and stray light in colorimetric detection simultaneously, the biggish optical filter of light passing can input more incident lights to improve reaction cup irradiation light intensity, the excitation signal of scattering turbidimetry and fluorescence detection is improved, to play multipurpose item detection and the purpose of detection accuracy can be improved.
Description
Technical field
The utility model relates to optical analysis detection technique field, refers specifically to a kind of compatible colorimetric, examined than turbid and fluorescence
The optical system of survey.
Background technique
Biochemistry detection principle has colorimetric, than turbid and excitation fluorescence method, and it is turbid and scattered that turbidimetry can be divided into transmittance again
It penetrates than turbid.The method that current automatic clinical chemistry analyzer uses is that transmission colorimetric and transmittance are turbid, and turbidimetry is due to depositing
In bias light, noise compares that scattering turbidimetry is poor, and current Biochemical Analyzer does not support the function of excitation fluorescence detection, respectively
Kind item detection is required to corresponding optical detection apparatus investment, and compatibility is very poor.Therefore, the prior art is to be improved and sends out
Exhibition.
Utility model content
The purpose of this utility model is that in view of the drawbacks of the prior art and insufficient, provide it is a kind of it is structurally reasonable, small in size,
Using flexible, can meet at present the compatible colorimetric of most optical detection requirements, than turbid and fluorescence detection optical system.
To achieve the goals above, the utility model uses following technical scheme:
A kind of compatible colorimetric described in the utility model, than turbid and fluorescence detection optical system, including radiation source,
Reaction cup and colorimetric spectral module, radiation source and colorimetric spectral module be respectively arranged on input path at left and right sides of reaction cup and
On transmitted light path, optical filter wheel is equipped between the radiation source and reaction cup, optical filter wheel is equipped with light hole and several narrow
Band optical filter, light hole and several narrow band filters be separately positioned on centered on optical filter wheel rotation axis and with input path phase
On the same circumference handed over；Refractive light paths on front side of the reaction cup are equipped with than turbid and fluorescence detection module.
According to above scheme, shaping lens are equipped between the radiation source and optical filter wheel.
According to above scheme, the diameter of the narrow band filter is greater than the diameter of light hole.
According to above scheme, the optical filter wheel is equipped with several mounting holes, and the diameter of several mounting holes is greater than light hole
Diameter, several narrow band filters are separately fixed on corresponding mounting hole.
According to above scheme, the diameter of the light hole is 2-3mm, sets that there are four narrow band filters on optical filter wheel, narrow
Effective light passing diameter with optical filter is 4-6mm.
According to above scheme, it is described than turbid and fluorescence detection module include spectroscope, than turbid detector, fluorescent optical filter and
Fluorescent probe, spectroscope and is successively set in the refractive light paths on front side of reaction cup than turbid detector, fluorescent optical filter and glimmering
Optical detector is successively set on spectroscopical reflected light path.
According to above scheme, collimation lens is equipped between the reaction cup and spectroscope.
According to above scheme, the spectroscope and than being equipped between turbid detector than turbid condenser lens, fluorescent optical filter and
Fluorescent foci lens are equipped between fluorescent probe.
The utility model has the beneficial effect that the utility model is structurally reasonable, will than the setting of turbid and fluorescence detection module with
In the vertical refractive light paths of the transmission direction of reaction cup, colorimetric is corresponded to, than turbid and fluorescence detection by rotating filtering piece wheel, simultaneously
Lesser light hole reduces the influence of amount of reagent and stray light in colorimetric detection, and the biggish optical filter of light passing can input more
Incident light improves the excitation signal of scattering turbidimetry and fluorescence detection, to play multipurpose item to improve reaction cup irradiation light intensity
The purpose of detection accuracy is surveyed and be can be improved in visual inspection.
Detailed description of the invention
Fig. 1 is the overall structure diagram of the utility model；
Fig. 2 is the turbid fluorescence detection module section structural schematic diagram of ratio of the utility model；
Fig. 3 is the optical filter wheel modular construction schematic diagram of the utility model.
In figure:
1, radiation source；2, optical filter wheel；3, than turbid and fluorescence detection module；11, reaction cup；12, colorimetric spectral module；
21, light hole；22, narrow band filter；23, shaping lens；24, mounting hole；31, collimation lens；32, spectroscope；33, than turbid spy
Survey device；34, than turbid condenser lens；35, fluorescent optical filter；36, fluorescent probe；37, fluorescent foci lens.
Specific embodiment
The technical solution of the utility model is illustrated with embodiment with reference to the accompanying drawing.
As shown in Figure 1-3, a kind of compatible colorimetric described in the utility model, than turbid and fluorescence detection optical system,
Including radiation source 1, reaction cup 11 and colorimetric spectral module 12, radiation source 1 and colorimetric spectral module 12 are respectively arranged on reaction
In the input path and transmitted light path of 11 left and right sides of cup, optical filter wheel 2 is equipped between the radiation source 1 and reaction cup 11,
Optical filter wheel 2 is equipped with light hole 21 and several narrow band filters 22, and light hole 21 and several narrow band filters 22 are respectively set
On the same circumference intersected centered on 2 rotation axis of optical filter wheel and with input path；The refraction of 11 front side of reaction cup
Optical path is equipped with than turbid and fluorescence detection module 3, described to be arranged than turbid fluorescence detection module 3 in radiation source 1 and reaction cup 11
Vertical direction on, by receive light excited in reaction cup 11 generation scattered light signal be scattered than it is turbid detection and it is glimmering
Light excitation-detection avoids the problem that the interference of bias light existing for the turbid detection of existing transmittance, poor signal to noise, while by spectral colorimetric
The compatible biochemistry detection instrument to obtain compact-sized, using flexible, perfect in shape and function of module 12.
Above-mentioned input path and transmitted light path are on the same straight line of reaction cup 11, so that radiation source 1 be made to send out
For light out by input path to be projeced into reaction cup 11, light generates optical signal transmissive and scattering light in reaction cup 11
Signal, wherein optical signal transmissive continues to propagate along transmitted light path, and scattered light signal is propagated along refractive light paths, and the refractive light paths are general
Refer to any scattering direction other than input path and transmitted light path, the preferred refractive light paths of the utility model and transmitted light path hang down
Directly to obtain strongest scattered light signal and optimal topology layout, then the refractive light paths can be using transmitted light path as axle center
It is any radial.
The output light of the preferred radiation source 1 of the utility model is screened by filter disc halo 2, and workflow is as follows:
When colorimetric is divided and detects, the rotation of optical filter wheel 2 is in light hole 21 in input path, passes through the light hole 21 of small diameter
The diameter of control transmission hot spot is to meet testing requirements, and the light of radiation source 1 is after the collimation of shaping lens 23 by logical
Unthreaded hole 21 injects reaction cup 11, and the optical signals colorimetric detection module 12 that reaction cup 11 transmits is received and analyzed, colorimetric detection mould
Block 12 can be used grating beam splitting mode or be realized by the mode that light splitting lens array decomposes each wavelength channels；When than turbid detection,
Rotating filtering piece wheel 2 is in the narrow band filter 22 of corresponding wavelength in input path, and radiation source 1 generates biggish transmitted light
To meet than turbid and fluorescence detection demand, the scattering light that reaction cup 11 exports penetrates after spectroscope 32 and by than turbid detector 35 spot
It receives；When exciting fluorescence detection, scattering light is reflected by spectroscope 32 and is penetrated after fluorescent optical filter 35 by fluorescent probe 36
It receives.
Shaping lens 23 are equipped between the radiation source 1 and optical filter wheel 2, shaping lens 23 are for converging radiation source
1 output light simultaneously forms collimated light signal to be projeced into reaction cup 11, and the hot spot that shaping lens 23 focus should completely cover narrowband
Optical filter 22, to provide the light intensity for meeting detection demand.
The diameter of the narrow band filter 22 is greater than the diameter of light hole 21, due to being incident on the light intensity of reaction cup 11
Related to scattered signal intensity, wherein the more big then scattered signal of incident intensity is bigger, and the hot spot the big, the fluorescence signal that excites more
By force, therefore the utility model respectively corresponds colorimetric by the light hole 21 and larger-diameter narrow band filter 22 of small diameter and examines
Survey, scattering turbidimetry and fluorescence detection can effectively improve detection signal strength and accuracy；The preferred light hole 21 of the utility model
Diameter be 2-3mm, set on optical filter wheel 2 there are four narrow band filter 22, effective light passing diameter of narrow band filter 22 is 4-
6mm。
The optical filter wheel 2 is equipped with several mounting holes 23, and the diameter of several mounting holes 23 is greater than the diameter 21 of light hole,
Several narrow band filters 22 are separately fixed on corresponding mounting hole 23；The narrow band filter 22 is fixed by detachable structure
On mounting hole 23, thus in 23 position of mounting hole of limited quantity by replacement narrow band filter 22 to expand detection range,
Improve the using flexible of optical detection apparatus.
It is described to be visited than turbid and fluorescence detection module 3 including spectroscope 32, than turbid detector 33, fluorescent optical filter 35 and fluorescence
It surveys device 36, spectroscope 32 and is successively set in the refractive light paths of the front side of reaction cup 11 than turbid detector 33, fluorescent optical filter 35
It is successively set on fluorescent probe 36 on the reflected light path of spectroscope 32.
Collimation lens 31 is equipped between the reaction cup 11 and spectroscope 32, the collimation lens 31 is for improving scattering light letter
Number output intensity.
The spectroscope 32 and than being equipped between turbid detector 33 than turbid condenser lens 34, fluorescent optical filter 35 and fluorescence are visited
It surveys and is equipped with fluorescent foci lens 37 between device 36, scattering turbidimetry condenser lens 34 and fluorescent foci lens 37, which are respectively used to improve, to be divided
The light signal strength of the conduction output of light microscopic 32.
The above description is only a preferred embodiment of the present invention, therefore all according to described in the utility model patent application range
The equivalent change or modification done of structure, feature and principle, be included in the scope of the utility model patent application.
Claims (8)
1. a kind of compatible colorimetric, than turbid and fluorescence detection optical system, including radiation source (1), reaction cup (11) and ratio
Color spectral module (12), radiation source (1) and colorimetric spectral module (12) are respectively arranged on the incidence at left and right sides of reaction cup (11)
In optical path and transmitted light path, it is characterised in that: be equipped with optical filter wheel (2) between the radiation source (1) and reaction cup (11), filter
Mating plate wheel (2) is equipped with light hole (21) and several narrow band filters (22), light hole (21) and several narrow band filters (22)
It is separately positioned on the same circumference intersected centered on optical filter wheel (2) rotation axis and with input path；The reaction cup
(11) refractive light paths on front side of are equipped with than turbid and fluorescence detection module (3).
2. compatible colorimetric according to claim 1, than turbid and fluorescence detection optical system, it is characterised in that: described
Shaping lens (23) are equipped between radiation source (1) and optical filter wheel (2).
3. compatible colorimetric according to claim 1, than turbid and fluorescence detection optical system, it is characterised in that: described
The diameter of narrow band filter (22) is greater than the diameter of light hole (21).
4. compatible colorimetric according to claim 3, than turbid and fluorescence detection optical system, it is characterised in that: described
Optical filter wheel (2) is equipped with several mounting holes (24), and the diameter of several mounting holes (24) is greater than the diameter of light hole (21), several
Narrow band filter (22) is separately fixed on corresponding mounting hole (24).
5. compatible colorimetric according to claim 4, than turbid and fluorescence detection optical system, it is characterised in that: described
The diameter of light hole (21) is 2-3mm, is set on optical filter wheel (2) there are four narrow band filter (22), narrow band filter (22)
Effective light passing diameter is 4-6mm.
6. compatible colorimetric according to claim 1, than turbid and fluorescence detection optical system, it is characterised in that: described
It include spectroscope (32), than turbid detector (33), fluorescent optical filter (35) and fluorescent probe than turbid and fluorescence detection module (3)
(36), it spectroscope (32) and is successively set in the refractive light paths on front side of reaction cup (11) than turbid detector (33), fluorescence filters
Piece (35) and fluorescent probe (36) are successively set on the reflected light path of spectroscope (32).
7. compatible colorimetric according to claim 6, than turbid and fluorescence detection optical system, it is characterised in that: described
Collimation lens (31) are equipped between reaction cup (11) and spectroscope (32).
8. compatible colorimetric according to claim 6, than turbid and fluorescence detection optical system, it is characterised in that: described
Spectroscope (32) and than between turbid detector (33) be equipped with than turbid condenser lens (34), fluorescent optical filter (35) and fluorescent probe
(36) fluorescent foci lens (37) are equipped between.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820720922.3U CN208547572U (en) | 2018-05-15 | 2018-05-15 | A kind of compatible colorimetric, than turbid and fluorescence detection optical system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820720922.3U CN208547572U (en) | 2018-05-15 | 2018-05-15 | A kind of compatible colorimetric, than turbid and fluorescence detection optical system |
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| CN208547572U true CN208547572U (en) | 2019-02-26 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109975888A (en) * | 2019-04-02 | 2019-07-05 | 中国科学院合肥物质科学研究院 | A kind of adjustable target optical spectrum characteristic measuring system of band combination band width configuration |
| CN111413327A (en) * | 2020-04-28 | 2020-07-14 | 上海泰辉生物科技有限公司 | Dual mode detection system and dual mode detection method |
| WO2022078132A1 (en) * | 2020-10-16 | 2022-04-21 | 石家庄禾柏生物技术股份有限公司 | Multi-methodology combined optical path |
-
2018
- 2018-05-15 CN CN201820720922.3U patent/CN208547572U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109975888A (en) * | 2019-04-02 | 2019-07-05 | 中国科学院合肥物质科学研究院 | A kind of adjustable target optical spectrum characteristic measuring system of band combination band width configuration |
| CN111413327A (en) * | 2020-04-28 | 2020-07-14 | 上海泰辉生物科技有限公司 | Dual mode detection system and dual mode detection method |
| WO2022078132A1 (en) * | 2020-10-16 | 2022-04-21 | 石家庄禾柏生物技术股份有限公司 | Multi-methodology combined optical path |
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