CN208511024U - A kind of magnetic induction triggering myoelectricity collector suitable for transcranial magnetic stimulation instrument - Google Patents

A kind of magnetic induction triggering myoelectricity collector suitable for transcranial magnetic stimulation instrument Download PDF

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CN208511024U
CN208511024U CN201721088259.1U CN201721088259U CN208511024U CN 208511024 U CN208511024 U CN 208511024U CN 201721088259 U CN201721088259 U CN 201721088259U CN 208511024 U CN208511024 U CN 208511024U
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circuit
magnetic induction
myoelectricity
module
collector
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高飞
王克成
李阳
施雯
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Nanjing Weisi Medical Polytron Technologies Inc
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Nanjing Weisi Medical Polytron Technologies Inc
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Abstract

The utility model discloses a kind of magnetic induction suitable for transcranial magnetic stimulation instrument to trigger myoelectricity collector, characterized in that including processor module, myoelectricity acquisition amplifying circuit and magnetic induction trigger circuit;The data of the myoelectricity acquisition amplifying circuit and magnetic induction trigger circuit are transferred to processor module;The magnetic induction trigger circuit includes resonant inducing circuit, integrated circuit, the signal input module being all connected with the integrated circuit and external filter module.The utility model it is achieved the utility model has the advantages that do not need triggering line synchro and data line be connected with computer, the various interference that can be introduced to avoid TMS host and computer, it avoids the need for that 50Hz trap circuit is added in myoelectricity collector, the frequency of human body electromyography signal is generally between 20-450Hz, 50Hz trap circuit is other than filtering out 50Hz interference, also effective human body 50Hz electromyography signal is filtered out, influences measurement accuracy.

Description

A kind of magnetic induction triggering myoelectricity collector suitable for transcranial magnetic stimulation instrument
Technical field
The present invention relates to a kind of myoelectricity collectors, and in particular to a kind of magnetic induction triggering flesh suitable for transcranial magnetic stimulation instrument Electric collector.
Background technique
It is a kind of mode being widely recognized as that TMS cooperation myoelectricity collector, which is used in combination, acts on movement skin using TMS Layer, when reaching stimulus threshold, Muscle Electricity Level Inducing Apparatus can detecte corresponding myoelectricity evoked potential signal, by measuring myoelectricity Time difference between when Evoked ptential and TMS start stimulation evaluates motor cortex to the neural conduction time between corresponding muscle. The neural conduction time of normal person has the people of sufferer or damage to nerve between 20-35ms, and nerve conduction can relatively slow or nothing The reaction of method inducing myoelectric potential.On the other hand, TMS is for when treating, meeting to be with the intensity threshold of the triggering Motion Evoked Potential of patient (MT) according to, output is usually stimulated with the reality output intensity of the 80%-120% of threshold value (MT), to realize the purpose for the treatment of.
Shown in implementation Fig. 1 of usual this application, connected between TMS host and myoelectricity collector by triggering line synchro It connects.While single, which stimulates, to be occurred, stimulation host generates a synchronous TTL signal, triggers myoelectricity by synchronous firing line and adopts Storage acquires electromyography signal, and doctor acquires waveform oneself by electromyogram and calculates neural conduction time.This mode seals in net electricity The interference (electronic impulse group, electrostatic) in source is easily entered in collector by line synchro, and collector signal interruption even flesh is caused Electricity acquisition abnormal signal, brings the risk of mistaken diagnosis.In addition stimulate the power frequency electric 50Hz interference of host itself also can be with line synchro Myoelectricity collector is sealed in, all 50Hz sine interference wave signals of waveform of display are caused, and normal myoelectricity letter cannot be acquired Number.
Summary of the invention
To solve the deficiencies in the prior art, the purpose of the present invention is to provide a kind of magnetic strengths suitable for transcranial magnetic stimulation instrument Myoelectricity collector should be triggered, do not need triggering line synchro and data line can be connected with computer, can to avoid TMS host with And the various interference that computer introduces, the problem of 50Hz trap circuit is added in myoelectricity collector is avoided the need for, is greatly mentioned The accuracy of high measurement.
In order to achieve the above objectives, the present invention adopts the following technical scheme that:
A kind of magnetic induction suitable for transcranial magnetic stimulation instrument triggers myoelectricity collector, characterized in that including processor module, Myoelectricity acquires amplifying circuit and magnetic induction trigger circuit;The data of the myoelectricity acquisition amplifying circuit and magnetic induction trigger circuit are equal It is transferred to processor module;The magnetic induction trigger circuit includes resonant inducing circuit, integrated circuit, equal with the integrated circuit The signal input module of connection and external filter module;The resonant inducing circuit is used for the sense that capture space radiation field generates Voltage is answered, pulsewidth is consistent with the pulsed magnetic field that stimulating coil generates;The integrated circuit includes that level detector, level are automatic Control circuit and amplifier controller;The induced voltage pulse that the signal input module arrives resonant inducing circuit inductance is believed Number it is delivered to the level detector of IC interior;The level detector is different according to the amplitude of output signal, by its turn It is changed to different direct current signals and is sent into level automatic control circuit;The automatic level control circuit sends level detector Direct current signal compared with reference current relatively after, export direct current signal to amplifier controller;The amplifier controller according to Obtained direct current signal changes the amplification factor of amplifier.
A kind of magnetic induction suitable for transcranial magnetic stimulation instrument above-mentioned triggers myoelectricity collector, characterized in that described integrated Circuit uses MC2830.
A kind of magnetic induction suitable for transcranial magnetic stimulation instrument above-mentioned triggers myoelectricity collector, characterized in that described integrated Negative feedback module is additionally provided on circuit;The negative feedback module is for adjusting between magnetic induction trigger circuit and stimulation racket head Significant response distance.
A kind of magnetic induction suitable for transcranial magnetic stimulation instrument above-mentioned triggers myoelectricity collector, characterized in that described external The output end of filter module is provided with diode, for rectifying the TTL triggering level of outputting standard.
A kind of magnetic induction suitable for transcranial magnetic stimulation instrument above-mentioned triggers myoelectricity collector, characterized in that further includes nothing Line sending module, for wirelessly sending the data of processor module.
A kind of magnetic induction suitable for transcranial magnetic stimulation instrument above-mentioned triggers myoelectricity collector, characterized in that further includes electricity Pole piece acquires amplifying circuit with myoelectricity by electrode wires and is connected.
Advantageous effects of the invention:
I) signal of specific frequency can be amplified, the false triggering in other magnetic fields of space will not be caused;
Ii) the significant response distance between adjustable magnetic induction trigger circuit and stimulation racket head guarantees that multiple devices exist In use, will not interact in same room;
Iii) guarantee the real-time of response, the triggering TTL signal rising edge of generation and magnetic field start the time between stimulation Difference < 120uS can satisfy the error requirements for checking neural conduction time completely;
Iv it) does not need triggering line synchro and data line is connected with computer, can be introduced to avoid TMS host and computer Various interference avoid the need for that 50Hz trap circuit is added in myoelectricity collector, and the frequency of human body electromyography signal is generally in 20- Between 450Hz, 50Hz trap circuit also filters out effective human body 50Hz electromyography signal other than filtering out 50Hz interference, influences Measurement accuracy.
Detailed description of the invention
Fig. 1 is traditional Neural stem cell induced movement potential acquisition schematic diagram;
Fig. 2 is induced movement potential acquisition schematic diagram of the present invention;
Fig. 3 is the structural block diagram of the present apparatus;
Fig. 4 is resonant inducing circuit diagram;
Fig. 5 is integrated circuit and coupled circuit diagram;
Fig. 6 is MC2830 internal circuit configuration figure;
Fig. 7 is ALC amplifier control principle drawing
Fig. 8 is the myoelectric waveform schematic diagram interfered under normal muscle quiescent condition by 50Hz;
Fig. 9 is the schematic diagram of myoelectric waveform under normal muscle quiescent condition.
Specific embodiment
The invention will be further described below in conjunction with the accompanying drawings.Following embodiment is only used for clearly illustrating the present invention Technical solution, and not intended to limit the protection scope of the present invention.
Block diagram of the present invention gives Neural stem cell host, Neural stem cell response of host, stimulation as shown in Fig. 2, PC machine sends stimulation order Coil generates pulsed magnetic field.Magnetic induction triggering myoelectricity collector can synchronize inductive spacing radiation field, and the myoelectricity of acquisition is believed Number be wirelessly sent to PC machine, PC machine by the analysis to electromyography signal, calculate automatically neural conduction time, from It is dynamic to identify Motion Evoked Potential and set stimulus threshold automatically.
The structure of magnetic induction triggering myoelectricity collector is shown in Fig. 3, working principle: each single stimulation, stimulating coil can produce The pulsed magnetic field of raw fixed pulse width T.
Myoelectricity collector includes magnetic induction trigger device by resonant inducing circuit shown in Fig. 4, and L1, C7, C8 are formed humorous Shake circuit, and parameter meetsT is the pulsewidth of pulsed magnetic field.The pulsed magnetic field warp that coil generates Space radiation generates induced voltage via resonance circuit, and the pulse width of induced voltage is also T.
As shown in figure 5, the induced voltage pulse signal generated through C6, is input to 2 feet of U1 after the bandpass filtering of R4, C2. U1 has selected MC2830, and internal circuit structure is shown in Fig. 6.MC2830 is internally integrated level detector, level automatic control circuit And amplifier controller.
It is sent after amplifier amplifies from No. 2 pin input signals in IC interior to level detector, level detection Device forms negative feedback network by R2, R5 and C4 and amplifier, and changing parameter can control the filtering parameter of amplifier and put Big multipleWherein jw indicates amplifier frequency response.
By the way that the value of R6 and C5 is arranged, the sensitivity of level detector can control.As shown in fig. 7, level detector Output controls the amplification factor of input amplifier by ALC unit.When detecting level lower than setting value, ALC unit does not change The amplification factor of amplifier;When detecting level higher than setting value, ALC unit step-down amplifier amplification factor, so that output Signal amplitude is maintained within rated value.
After the output signal of level detector is amplified using level amplifier, DC Shifter and Noise are inputted Monitor.The output signal dc-bias of DC Shifter determines by the parameter of R6 and C9, Noise Monitor by R1 with And the rise time of the parameter setting noise signal of R3 determines output noise monitoring level.The output signal of DC Shifter with make an uproar Sound monitoring level is compared by comparator, and the output of comparator is square-wave signal, and pulsewidth is consistent with output magnetic field pulsewidth T, warp D2 rectification output is TTL triggering level.
The advantages of this magnetic induction trigger circuit is can to amplify to the signal of specific frequency, will not cause other magnetic of space The false triggering of field;It can be effective between adjustable magnetic induction trigger circuit and stimulation racket head by the setting of R2, R5 and C4 Respond distance, it is ensured that multiple devices are in same room in use, will not interact;This magnetic induction trigger circuit guarantees The real-time of response, the triggering TTL signal rising edge of generation and magnetic field start to stimulate between time difference < 120uS, completely may be used To meet the error requirements for checking neural conduction time;Additionally, due to not needing triggering line synchro and data line and computer phase Even, the various interference that can be introduced to avoid TMS host and computer, avoid the need for that 50Hz trap is added in myoelectricity collector Circuit, the frequency of human body electromyography signal generally between 20-450Hz, also will other than filtering out 50Hz interference by 50Hz trap circuit Effective human body 50Hz electromyography signal filters out, and influences measurement accuracy.
Human body electromyography signal is adopted by the signal of electrode slice, electrode wires, electromyographic signal collection amplifying circuit to microprocessor Collect program.It is interrupted when microprocessor receives the response rising edge triggering of TTL triggering level, first myoelectricity data is added Mark is expressed as first myoelectricity data, and myoelectricity data is transmitted to wireless sending module.Wireless sending module is by flesh Electric data packet is sent to computer and carries out data analysis.
Evoked ptential auto-analyzer procedure in computer includes neural conduction time automatic identification function, exercise induced electricity Position threshold value automatic identification function and stimulus threshold automatic identification.The automatic analysis program of Evoked ptential point can automatic identification Evoked ptential Initial point, wave crest point and trough point.The settable Motion Evoked Potential threshold value (usually 50uV) of user.As shown in fig. 7, X refers to wave crest/wave trough position point that software automatically identifies in figure, by taking 50uV as an example, if the peak-to-peak value of Evoked ptential is greater than 50uV is then automatically recognized as effective induced movement current potential.It calculates by the myoelectricity data point with mark to Evoked ptential initial point Between collection point digit T1, be multiplied with sample frequency F1, obtain neural conduction time Δ t.Making nervous function damage inspection It, can be with neural conduction time whether just frequently as judging basis and when nerve rehabilitation evaluation.Program, which automatically records, to be reached The stimulus intensity of Motion Evoked Potential threshold value, if it is continuous 10 times stimulation can induced movement current potential, automatic program identification For stimulus threshold.Stimulus threshold provides for personal therapeutic scheme and provides accurate foundation with the output treatment of much intensity.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, without departing from the technical principles of the invention, several improvement and deformations can also be made, these improvement and deformations Also it should be regarded as protection scope of the present invention.

Claims (6)

1. a kind of magnetic induction suitable for transcranial magnetic stimulation instrument triggers myoelectricity collector, characterized in that including processor module, flesh Electricity acquisition amplifying circuit and magnetic induction trigger circuit;The data of the myoelectricity acquisition amplifying circuit and magnetic induction trigger circuit pass It is defeated by processor module;
The magnetic induction trigger circuit includes that resonant inducing circuit, integrated circuit, the signal that is all connected with the integrated circuit are defeated Enter module and external filter module;
The resonant inducing circuit is used for the induced voltage that capture space radiation field generates, what pulsewidth and stimulating coil generated Pulsed magnetic field is consistent;
The integrated circuit includes level detector, level automatic control circuit and amplifier controller;The signal input Module by resonant inducing circuit inductance to induced voltage pulse signal be delivered to the level detector of IC interior;It is described Level detector is different according to the amplitude of output signal, is converted into different direct current signals and is sent into level automatic control electricity Road;The direct current signal that the automatic level control circuit sends level detector compared with reference current relatively after, export direct current Signal is to amplifier controller;The amplifier controller changes the amplification factor of amplifier according to obtained direct current signal.
2. a kind of magnetic induction suitable for transcranial magnetic stimulation instrument according to claim 1 triggers myoelectricity collector, feature It is that the integrated circuit uses MC2830.
3. a kind of magnetic induction suitable for transcranial magnetic stimulation instrument according to claim 1 triggers myoelectricity collector, feature It is to be additionally provided with negative feedback module on the integrated circuit;The negative feedback module is for adjusting magnetic induction trigger circuit and thorn Swash the significant response distance between racket head.
4. a kind of magnetic induction suitable for transcranial magnetic stimulation instrument according to claim 1 triggers myoelectricity collector, feature It is that the output end of the external filter module is provided with diode, for rectifying the TTL triggering level of outputting standard.
5. a kind of magnetic induction suitable for transcranial magnetic stimulation instrument according to claim 1 triggers myoelectricity collector, feature Being further includes wireless sending module, for wirelessly sending the data of processor module.
6. a kind of magnetic induction suitable for transcranial magnetic stimulation instrument according to claim 1 triggers myoelectricity collector, feature Being further includes electrode slice, acquires amplifying circuit with myoelectricity by electrode wires and is connected.
CN201721088259.1U 2017-08-29 2017-08-29 A kind of magnetic induction triggering myoelectricity collector suitable for transcranial magnetic stimulation instrument Active CN208511024U (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114917479A (en) * 2022-06-30 2022-08-19 深圳英智科技有限公司 Transcranial magnetic pulse interference filtering method and system and electronic equipment
CN116139409A (en) * 2023-04-17 2023-05-23 江西朴拙医疗设备有限公司 Anti-interference magnetic therapy detection system, threshold detection method and all-in-one machine
CN116510183A (en) * 2023-06-28 2023-08-01 南昌大学第一附属医院 Transcranial magnetic stimulation device, electronic device, and storage medium
US11794029B2 (en) 2016-07-01 2023-10-24 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US11806528B2 (en) 2020-05-04 2023-11-07 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11826565B2 (en) 2020-05-04 2023-11-28 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11878162B2 (en) 2016-05-23 2024-01-23 Btl Healthcare Technologies A.S. Systems and methods for tissue treatment
US11883643B2 (en) 2016-05-03 2024-01-30 Btl Healthcare Technologies A.S. Systems and methods for treatment of a patient including RF and electrical energy
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11883643B2 (en) 2016-05-03 2024-01-30 Btl Healthcare Technologies A.S. Systems and methods for treatment of a patient including RF and electrical energy
US11896821B2 (en) 2016-05-23 2024-02-13 Btl Healthcare Technologies A.S. Systems and methods for tissue treatment
US11878162B2 (en) 2016-05-23 2024-01-23 Btl Healthcare Technologies A.S. Systems and methods for tissue treatment
US11794029B2 (en) 2016-07-01 2023-10-24 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US11878167B2 (en) 2020-05-04 2024-01-23 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11806528B2 (en) 2020-05-04 2023-11-07 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11813451B2 (en) 2020-05-04 2023-11-14 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11826565B2 (en) 2020-05-04 2023-11-28 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
CN114917479A (en) * 2022-06-30 2022-08-19 深圳英智科技有限公司 Transcranial magnetic pulse interference filtering method and system and electronic equipment
CN116139409A (en) * 2023-04-17 2023-05-23 江西朴拙医疗设备有限公司 Anti-interference magnetic therapy detection system, threshold detection method and all-in-one machine
CN116510183B (en) * 2023-06-28 2023-09-19 南昌大学第一附属医院 Transcranial magnetic stimulation device, electronic device, and storage medium
CN116510183A (en) * 2023-06-28 2023-08-01 南昌大学第一附属医院 Transcranial magnetic stimulation device, electronic device, and storage medium

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