CN208506357U - A kind of glass slide bracket - Google Patents

A kind of glass slide bracket Download PDF

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Publication number
CN208506357U
CN208506357U CN201821176874.2U CN201821176874U CN208506357U CN 208506357 U CN208506357 U CN 208506357U CN 201821176874 U CN201821176874 U CN 201821176874U CN 208506357 U CN208506357 U CN 208506357U
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China
Prior art keywords
glass slide
supporting plate
loading slot
bracket
transparent supporting
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Active
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CN201821176874.2U
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Chinese (zh)
Inventor
邱学奎
李鸿瑞
贺艳丽
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WUHAN KANGSHENGDA MEDICAL INSTITUTE Co Ltd
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WUHAN KANGSHENGDA MEDICAL INSTITUTE Co Ltd
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Abstract

The utility model provides a kind of glass slide bracket, it include: the positioning framework that the bracket body includes transparent supporting plate He is attached on the transparent supporting plate, the positioning framework is recessed downwards the loading slot formed for placing glass slide, and the transparent supporting plate is equipped with the grid coordinate system for positioning target sample on the glass slide in the loading slot.Glass slide bracket provided by the utility model, by the transparent bracket for being provided with grid coordinate system, target sample to be placed in the glass slide on transparent bracket carries out precise positioning, it is observed again after facilitating the later period to handle target sample, reduce the time manually positioned, greatly improves work efficiency.

Description

A kind of glass slide bracket
Technical field
The utility model relates to the field of medical instrument technology, more particularly, to a kind of glass slide bracket.
Background technique
Glass slide is the sheet glass for placing experimental material, is usually rectangle, and has good translucency, and by use Way can be divided into microscope slides and cell culture glass slide, wherein microscope slides can be used smear method, pressed disc method, load method and Microtomy is to place experimental material, and observation bacterium, unicellular organism, Microalgae, blood, animals and plants are loose under the microscope The experimental materials such as tissue, spermary and pollen, in fields such as scientific research, medical inspection, disease surveillance, animals and plants inspection and quarantine It is widely used.
For the ease of observing endocellular chromosome and its change procedure under the microscope, it is necessary first to obtain chromosome sample And be fixed on glass slide, then glass slide is placed on microscopical objective table to observe, due to microscope slide It can also be had differences between the poor and different microscope carrier of the included coordinate precision of platform, search target sample after calibration again This difficulty is larger.Want to pick up physical location corresponding to result images on glass slide, can only spend at present a large amount of Time is slowly found, this is also that experimenter currently feels the most helpless but has to the case where facing.In actual operation, The chromosome bias due to caused by the operation error of experimenter is almost that can not thoroughly prevent, and then may cause to sentence The coloration result of reading be it is inaccurate, be embodied directly in the reduction of microscopy precision, and potentially affect a certain position patient, certain One experiment or certain a collection of test sample, if it is in the public health event of burst, influence may be more serious.
Therefore, the accurate positioning for realizing target sample on glass slide is a urgent problem needed to be solved.
Utility model content
(1) technical problems to be solved
The purpose of the utility model is to provide a kind of glass slide brackets, can provide accurate seat for the sample on glass slide Cursor position, convenient for observing after sample post-processing again.
(2) technical solution
In order to solve the above-mentioned technical problem, the utility model provides a kind of glass slide bracket, comprising: the bracket body packet The positioning framework for including transparent supporting plate and being attached on the transparent supporting plate, the positioning framework are recessed downwards formation for placing load The loading slot of slide, the transparent supporting plate are equipped with the grid for positioning target sample on the glass slide in the loading slot Coordinate system.
Preferably, the origin of the grid coordinate system is overlapped with any vertex of the loading trench bottom, and the grid is sat The horizontal and vertical of mark system is respectively equipped with the identical grid lines of preset interval.
Preferably, the grid coordinate system is horizontally and vertically respectively equipped with mutually different identifier, the mark Symbol is used to identify the region between adjacent net ruling.
Preferably, the preset interval of the grid lines is 0.2mm~0.5mm.
Preferably, for the loading slot through the side of the bracket body, the glass slide is horizontal along the loading slot Into and out.
Preferably, glass slide fixing clamp, the glass slide are equipped with close to the position of the loading slot on the positioning framework Fixing clamp includes rebound piece, and the rebound piece withstands the glass slide and is located at the fixation position of the loading trench bottom.
Preferably, the bottom of the loading slot is overlapped with the upper surface of the transparent supporting plate.
Preferably, the positioning framework and the transparent supporting plate are strengthening glass sheets, the positioning framework and described Bright supporting plate integrated molding is to form the bracket body.
(3) beneficial effect
Glass slide bracket provided by the utility model, by being provided with the transparent bracket of grid coordinate system, to will set Precise positioning is carried out in the target sample in the glass slide on transparent bracket, is carried out again after facilitating the later period to handle target sample Observation, reduces the time manually positioned, greatly improves work efficiency.
Detailed description of the invention
In order to illustrate the embodiment of the utility model or the technical proposal in the existing technology more clearly, below will be to embodiment Or attached drawing needed to be used in the description of the prior art is briefly described, it should be apparent that, the accompanying drawings in the following description is this Some embodiments of utility model, for those of ordinary skill in the art, without creative efforts, also Other drawings may be obtained according to these drawings without any creative labor.
Fig. 1 is a kind of structural schematic diagram of glass slide bracket of the utility model embodiment;
Fig. 2 is that glass slide is placed in the structural schematic diagram on bracket body in Fig. 1;
Fig. 3 is that glass slide is placed in the structural schematic diagram on bracket body when bracket body is integrated chemical conversion type in Fig. 1;
Appended drawing reference:
The transparent supporting plate of 1-;2- positioning framework;3- bracket body;
4- glass slide;5- loading slot;6- glass slide fixing clamp;
61- springs back piece;62- fixed link;7- stealth fixing bolt.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiment of the present utility model is described in further detail.Below Embodiment is not intended to limit the scope of the present invention for illustrating the utility model.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " is pacified Dress ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally Connection;It can be mechanical connection, be also possible to be electrically connected;Can be directly connected, can also indirectly connected through an intermediary, It can be the connection inside two elements.For the ordinary skill in the art, above-mentioned art can be understood with concrete condition The concrete meaning of language in the present invention.
With reference to Fig. 1, the present embodiment provides a kind of glass slide brackets, specifically include: bracket body 3, and bracket body 3 includes saturating Transparent supporting plate 1 can be arranged to by bright supporting plate 1 and positioning framework 2 for the ease of the production of glass slide bracket with positioning framework 2 Identical size.Wherein, positioning framework 2 is located at the surface of transparent supporting plate 1, and the lower surface of positioning framework 2 and transparent supporting plate 1 Upper surface be bonded to each other to form bracket body 3, bonding can be used in laminating type, connector is fixed or clamping device etc. is real It is existing;Recess forms one for placing the loading slot 5 of glass slide 4 to positioning framework 2 downwards, and loading slot 5 is cuboid or square. Further, it is equipped with grid coordinate system in the region due to being located at loading slot 5 on transparent supporting plate 1, grid coordinate system can be covered with The bottom section of entire loading slot 5, to the mesh made in advance on glass slide 4 when convenient for glass slide 4 being placed in loading slot 5 Standard specimen this progress framing, therefore, when the material of positioning framework 2 can not observe grid coordinate system, the depth of loading slot 5 is needed Be greater than or equal to positioning framework 2 thickness, when positioning framework 2 also use transparent material when, it is only necessary to its depth can satisfy Place glass slide 4;Certainly, the depth of loading slot 5 also should not be too large, and need to consider the stable structure of entire bracket body 3 Property and durability.Above-mentioned target sample can be used for chromosome karyotype analysis, solid tumor situ Analysis, mid-term phase in situ hybridization Analysis, histopathological analysis and cell pathology analysis etc..
In the above-described embodiments, it is read for the ease of the setting of grid coordinate system and coordinate, by the origin of grid coordinate system It is overlapped with any vertex of loading slot 5, by the fixed point of the origin of grid coordinate system and the loading trench bottom upper left corner in the present embodiment It is overlapped, the horizontal and vertical of grid coordinate system is arranged with the identical grid lines of preset interval, and the preset interval of grid lines is 0.2mm~0.5mm, its smaller setting accuracy of grid lines spacing in mesh coordinate area is also higher, specifically can be according to experiment The practical chromosome sectioning situation in room chooses suitable dimension.Such as: Marrow chromosome karyotyping, peripheral blood chromosome karyotyping And the grid spacing of 0.2mm or 0.3mm can be used in mid-term phase in situ hybridization;Solid tumor in situ hybridization and Histopathological Studies can Using the grid spacing etc. of 0.4mm or 0.5mm.
Wherein, lateral grid lines and longitudinal grid lines vertical interlaced form multiple equal-sized grids, remove upper left Other than first grid of angular vertex, the horizontal axis of grid coordinate system is located at the loading trench bottom leftmost side, and the longitudinal axis is located at loading slot bottom Portion most front side is respectively equipped with mutually different identifier on horizontal axis and the longitudinal axis, and identifier can be using letter, number, sieve Horse number and Greek symbol etc., identifier are used to identify the region between adjacent two grid lines, the mark of horizontal axis and the longitudinal axis The combination of symbol can demarcate the coordinate of any one grid.In the present embodiment, horizontal axis is successively identified using number from left to right, The longitudinal axis from top to bottom successively using letter mark, when the target sample on glass slide falls into a certain grid, i.e., number-letter relation table with Number combinatorics on words positions the target sample, such as: F8, i.e., the net that horizontal axis identifier is 8 and longitudinal axis identifier is F Glass slide 4 is fixed on identical position on bracket when observing and can directly be positioned by the coordinate by lattice, next time.In addition, For the ease of observation, the corresponding longitudinal axis of each grid can directly be identified in corresponding grid with the combination of horizontal axis identifier, Such as: F8 is shown by the modes such as brushing or carving in the grid that horizontal axis identifier is 8 and longitudinal axis identifier is F In, positioning coordinate can be quickly read when the target sample on glass slide is fallen in the grid for be shown as F8 in this way, is not needed Search horizontally and vertically upper corresponding identifier respectively again.
Certainly, in the above-described embodiments, by taking the observation of cell chromosome mid-term phase as an example, meeting in each cell of target sample There are the observed images of multiple chromosomes, only need to carry out positioning mark to the subsequent chromosome for needing secondary treatment or observing again Note, can quickly to be found when observation next time.
In the actual operation process, it is necessary first to the loading slot being placed in the glass slide 4 of subsidiary chromosome in bracket body 3 In 5, glass slide 4 can be fixed in the upper left corner by loading slot 5 by hold assembly, so that the upper left corner of glass slide 4 and net The origin of lattice coordinate system is overlapped.At this point, grid coordinate system is located at the lower section of glass slide 4, it is placed in light field microscope load again later Diagosis is carried out on object platform and is shot, for there are the mid-terms of query mutually can recorde its coordinate corresponded in grid coordinate system, The later period is facilitated to have access to the mid-term phase at the piece again, it can directly according to coordinate setting, mid-term be mutually understood herein when more people's diagosis It examines;In situ hybridization processing can be mutually carried out to coordinate mid-term herein if necessary to further diagnosis, the later period is read by fluorescence microscope Piece or shooting when can directly by before mark coordinate setting, accurate positioning zero deflection, can save 90% it is manual determine The position time, work efficiency is high;And different microscopes can be avoided to carry with unlimited microscope model using glass slide bracket positioning The inhomogenous phenomenon of object platform coordinatometer, it is convenient to search.
In the above-described embodiments, with reference to Fig. 2, for the ease of the pick-and-place of glass slide, hold assembly can be used glass slide and fix It presss from both sides 6 pairs of glass slides 4 to be fixed, glass slide fixing clamp 6 is located at the lower right position on positioning framework 2 close to loading slot 5, carries glass Piece fixing clamp 6 includes the fixed link 62 of rebound piece 61 and fixed rebound piece 61, and rebound piece 61 is around fixed link 62 in certain elasticity Rotation in range, the twisting resistance by springing back piece 61 can be in the same position in the upper left corner of loading slot 5 when installing glass slide 4 It sets.
On the basis of the above embodiments, it the placement in order to facilitate glass slide 4 on bracket body 3 and fetches, loading slot 5 Each side distinguish bracket body 3 adjacent thereto side it is parallel, loading slot 5 is through the side of bracket body 3, quite It is overlapped in 5 side of loading slot with the side of bracket body 3, forms a U-shaped opening on the side of bracket body 3, carry glass Piece 4 is horizontally inserted into loading slot 5 from the U-shaped opening or extracts out of loading slot 5.
In the above-described embodiments, in order to guarantee the stability of entire glass slide bracket, make when positioning framework 2 is to lower recess The bottom of loading slot 5 is located just at the upper surface of transparent supporting plate 1, i.e. the depth of loading slot 5 is exactly equal to the thickness of positioning framework 2 Degree, is not only convenient for the positioning coordinate of object observing sample in this way, but also can guarantee the structural behaviour of bracket.Specific glass slide 4 Size: length × width x thickness=75mm × 25mm × (1.0~1.2mm), the size of bracket body 3: length × width x thickness=95mm × 35mm × (2.0~2.2mm), the size of loading slot 5 are length × wide × depth=80mm × 30mm × (1.0~1.2mm).Certainly, Above-mentioned size is for reference only, specifically can be designed and optimize according to observation sample and actual experiment condition.
In order to further increase the intensity of bracket, with reference to Fig. 3, positioning framework 2 and transparent supporting plate 1 are strengthening glass sheets, Strengthening glass sheets are able to bear biggish compression, positioning framework 2 and transparent supporting plate 1 first can be used integrated molding system at this time Make, opens up loading slot 5 again then to form bracket body 3.With reference to Fig. 2, if positioning framework 2 is metal plate or other materials Matter, then bracket body 3 need in stealthy fixing bolt 7, stealthy fixing bolt 7 will be solid again after positioning framework 2 and 1 gluing of glass supporting plate Fixed connection.
Glass slide bracket provided by the embodiment of the utility model, by being provided with the transparent bracket of grid coordinate system, from And be placed on the target sample in transparent bracket upper slide and carry out precise positioning, it is carried out after facilitating the later period to handle target sample It observes again, reduces the time manually positioned, greatly improve work efficiency, to be provided quickly for medical diagnosis on disease Therapeutic scheme.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this Within the spirit and principle of utility model, any modification, equivalent replacement, improvement and so on should be included in the utility model Protection scope within.

Claims (8)

1. a kind of glass slide bracket characterized by comprising bracket body, the bracket body include transparent supporting plate and be sticked Positioning framework on the transparent supporting plate, the positioning framework are recessed downwards the loading slot formed for placing glass slide, institute Transparent supporting plate is stated in the loading slot equipped with the grid coordinate system for positioning target sample on the glass slide.
2. glass slide bracket according to claim 1, which is characterized in that the origin of the grid coordinate system and the loading Any vertex of slot is overlapped, and the horizontal and vertical of the grid coordinate system is respectively disposed with the identical grid lines of preset interval.
3. glass slide bracket according to claim 2, which is characterized in that the grid coordinate system is horizontally and vertically distinguished Equipped with mutually different identifier, the identifier is used to identify the region between adjacent net ruling.
4. glass slide bracket according to claim 2 or 3, which is characterized in that the preset interval of the grid lines is 0.2mm ~0.5mm.
5. glass slide bracket according to any one of claims 1 to 3, which is characterized in that the loading slot is through described The side of bracket body, the glass slide are horizontally inserted into and extract along the perforative side of the bracket body.
6. glass slide bracket according to claim 4, which is characterized in that close to the loading slot on the positioning framework Position is equipped with glass slide fixing clamp, and the glass slide fixing clamp includes rebound piece, and the rebound piece withstands the glass slide and makes Its fixation position for being located at the loading slot.
7. glass slide bracket according to any one of claim 1 to 3, which is characterized in that the bottom of the loading slot with The upper surface of the transparent supporting plate is overlapped.
8. glass slide bracket according to claim 7, which is characterized in that the positioning framework is with the transparent supporting plate Strengthening glass sheets, the positioning framework and the transparent supporting plate integrated molding are to form the bracket body.
CN201821176874.2U 2018-07-24 2018-07-24 A kind of glass slide bracket Active CN208506357U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821176874.2U CN208506357U (en) 2018-07-24 2018-07-24 A kind of glass slide bracket

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Application Number Priority Date Filing Date Title
CN201821176874.2U CN208506357U (en) 2018-07-24 2018-07-24 A kind of glass slide bracket

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Publication Number Publication Date
CN208506357U true CN208506357U (en) 2019-02-15

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111766694A (en) * 2020-07-20 2020-10-13 深圳市创能亿科科技开发有限公司 Method and system for acquiring microscope section position

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111766694A (en) * 2020-07-20 2020-10-13 深圳市创能亿科科技开发有限公司 Method and system for acquiring microscope section position

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