CN206656896U - A kind of drop piece instrument of chromosome karyotype analysis sample - Google Patents
A kind of drop piece instrument of chromosome karyotype analysis sample Download PDFInfo
- Publication number
- CN206656896U CN206656896U CN201720390313.1U CN201720390313U CN206656896U CN 206656896 U CN206656896 U CN 206656896U CN 201720390313 U CN201720390313 U CN 201720390313U CN 206656896 U CN206656896 U CN 206656896U
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- CN
- China
- Prior art keywords
- dropper
- geometrical clamp
- table top
- glass carrier
- outer shroud
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
It the utility model is related to a kind of drop piece instrument of chromosome karyotype analysis sample, including support 1, dropper geometrical clamp 2, glass carrier bench 3 and heating water tank 4, relative altitude by adjusting dropper geometrical clamp 2 and glass carrier bench 3 effectively controls the relative altitude of dropping liquid and slide, so as to effectively control the chromosome separation phase density on every slide, glass carrier bench outer shroud 302 can place multiple slides, being capable of the multiple slides of batch processing.The utility model is simple in construction, easy to use, reaches the purpose of standardization batch processing sample.
Description
Technical field
It the utility model is related to medical experiment and medical diagnostic techniqu field, and in particular to a kind of chromosome karyotype analysis mark
This drop piece instrument.
Background technology
Chromosome karyotype analysis, it is mainly used in the diagnosis and research of the genetic disease of chromosome abnormality.Human peripheral blood
The application of Culture Technique in Lymphocytes and Banded method, it can not only be differentiated according to banding pattern per item chromosome, moreover it is possible in depth
Study form, variation and the distortion of chromosome and its relation between phenotype or clinical symptoms.The length of chromosome, split coil method
Degree of scatter and integrated degree, played an important role in the analysis of chromosome result, thus obtain complete display dyeing
Body is the main path for improving its karyotype resolution.
At present, the pretreatment of cell is related generally in the specimen preparation procedure of chromosome karyotype analysis, it is hypotonic, piece is dripped, is baked
The process such as piece, the aobvious bands of G.Wherein universal usual drop chip technology is to draw cell suspension using suction pipe now, is then carried in distance
The upper vertical of 10-15 centimetres of slide is added drop-wise on slide, cell is scattered in slide.Then wave carrier piece is held, in water
Or so 2-3 minutes are fumigated on bath, make cell rupture, Chromosome spread.This process human factor is stronger, drips the height of piece distance
With the drop inclined angle of piece, excessive moisture is trapped in slide, above-mentioned factor in cell suspension drop when vapor fumigates slide
The density of chromosome is all directly affected, meanwhile, it is only capable of operating 1 slide every time, efficiency is low.
Utility model content
In view of the deficienciess of the prior art, the purpose of this utility model is that drop piece height can be unified by providing one kind,
Chromosome separation phase density on every slide can be control effectively, while handle and fumigate multiple slides, reached
To the effect of batch processing.To reach above-mentioned purpose, the technical solution adopted in the utility model is：It the utility model is related to one kind
The drop piece instrument of chromosome karyotype analysis sample, including support 1, and be fixed on support 1 adjustable dropper geometrical clamp 2, can turn
Dynamic glass carrier bench 3 and heating water tank 4.Support 1 is fixed in heating water tank 4, is run through among glass carrier bench 3 and is connected relatively, dropper
Geometrical clamp 2 is fixed on support 1, directly over glass carrier bench 3.Overall described glass carrier bench 3 is in groove-like, by interior table top 301
Formed with the two parts of outer shroud 302, interior table top 301 and outer shroud 302 are relative to be fitting to connection, tool instruction slide pair on interior table top 301
Positive arrow 6, instruction slide align, and make drop piece position more accurate.Rotated within outer shroud 302 centered on table top 301, outer shroud
302 can place multiple slides 8, it is possible thereby to handle and fumigate simultaneously multiple slides, reach the effect of batch processing；It is described
Heating water tank 4 include the heating rod 402 that cell body 401 and the bottom of cell body 401 are set, thus heating water tank produces vapor, smokes
Steam slide；Dropper 7 is provided with described dropper geometrical clamp 2, is set on the downward face glass carrier bench outer shroud 302 of described dropper mouth
The position of slide 8 put, thus makes drop piece more accurate.
It is further preferred that described dropper geometrical clamp 2, described dropper geometrical clamp 2 is adjusted by dropper jig arm 201, dropper
Section nut 202, dropper geometrical clamp adjusting nut 203 are made up of connecting rod 204, by rotating dropper geometrical clamp adjusting nut 203,
Dropper geometrical clamp 2 so as to adjust height of the dropper geometrical clamp 2 relative to glass carrier bench 3, therefore can unite along the vertical sliding motion of support 1
One drop piece height, can control effectively to the chromosome separation phase density on every slide.Adjusted by rotating dropper
Nut 202 adds the dropper 7 of different size, makes the dropper suitable for more specifications.Dropper geometrical clamp 2 is to realize along support 1
Move up and down and be defined, be not limited only to nut regulation, may also include other regulative modes, such as spring clip mode.
It is further preferred that the outer shroud 302 of described glass carrier bench 3 with interior table top 301 into angle, the angle number of degrees are 130 °-
170 °, have a scupper 5 on table top 301 in glass carrier bench 3, thus drop in cell suspension on slide, excessive moisture can flow into
Interior table top 301, on slide, caused waste liquid flows out Cellular retention from scupper 5, can be further on every slide
Chromosome separation phase density control effectively.
Brief description of the drawings
Fig. 1 is the utility model main structure diagram.
Fig. 2 is the utility model vertical section structural representation.
Fig. 3 is glass carrier bench overlooking the structure diagram.
1- supports, 2- droppers geometrical clamp, 201- droppers jig arm, 202- droppers adjusting nut, 203- droppers in Fig. 1~Fig. 3
Geometrical clamp adjusting nut, 204- connecting rods, 3- glass carrier benches, table top in 301- glass carrier benches, 302- glass carrier benches outer shroud, 4- heating water tanks,
401- cell bodies, 402- heating rods, 5- scuppers, 6- align arrow, 7- droppers, 8- slides.
Embodiment
For invention, features and effects of the present utility model can be further appreciated that, following examples are enumerated, and are coordinated attached
Figure describes in detail as follows.
Embodiment 1
As shown in FIG. 1 to 3, the purpose of this utility model is that providing one kind uniformly drop piece height and slide can incline
Rake angle, the chromosome separation phase density on every slide can be control effectively, while handle and fumigate multiple loads
Slide, reach the effect of batch processing.To reach above-mentioned purpose, the technical solution adopted in the utility model is：A kind of chromosome
The drop piece instrument of karyotyping sample, including support 1, adjustable dropper geometrical clamp 2, rotatable glass carrier bench 3 and heating water tank 4；Branch
Frame 1 is fixed in heating water tank 4, runs through among glass carrier bench 3 and relative connection, dropper geometrical clamp 2 are fixed on support 1, position
Directly over glass carrier bench 3.Overall described glass carrier bench 3 is in groove-like, and outer shroud 302 and interior table top 301 are into angle, by interior table top
301 and the two parts of outer shroud 302 composition, interior table top 301 and outer shroud 302 are relative to be fitting to connection, during table top 301 is within outer shroud 302
The heart rotates, and can place multiple slides 8, and tool indicates slide alignment arrow 6 on interior table top 301；Described dropper geometrical clamp 2,
Described dropper geometrical clamp 2 passes through connecting rod by dropper jig arm 201, dropper adjusting nut 202, dropper geometrical clamp adjusting nut 203
204 compositions；The heating rod 402 that described heating water tank 4 includes cell body 401 and the bottom of cell body 401 is set；Described dropper is fixed
Dropper 7 is provided with folder 2.
The angle of described glass carrier bench outer shroud 302 and interior table top 301 is 150 °.
Described dropper geometrical clamp 2, by rotating dropper geometrical clamp adjusting nut 203, dropper geometrical clamp 2 can be along support 1
Vertical sliding motion, height of the dropper geometrical clamp 2 relative to glass carrier bench 3 is adjusted, while can be added by rotating dropper adjusting nut 202
Enter the dropper 7 of different size.
Has a scupper 5 in described glass carrier bench 3 on table top 301.
In the utility model, unless otherwise clearly defined and limited, the term such as term " connection ", " fixation " should be done extensively
Reason and good sense solution, for example, it may be fixedly connected or be detachably connected, or integrally；Can mechanically connect, can also
It is electrical connection；Can be joined directly together, can also be indirectly connected by intermediary, can be two element internals connection or
The interaction relationship of two elements.For the ordinary skill in the art, can understand as the case may be above-mentioned
Concrete meaning of the term in the utility model.
Embodiment 2
A kind of drop piece instrument of chromosome karyotype analysis sample is the utility model is related to, heating water tank 4 is heated in advance, prepares
After the cell suspension of drop piece, take clean clammy slide 8 to be placed on the outer shroud 302 of rotatable glass carrier bench 3, aligned using instruction
Arrow 6 aligns slide 8, and the cell suspension of piece to be dripped is drawn using dropper 7, and rotation dropper adjusting nut 202 installs dropper 7
In dropper jig arm 201, rotation dropper geometrical clamp adjusting nut 203, to adjust dropper geometrical clamp 2 and glass carrier bench 3 on support
Between relative position, dropper geometrical clamp 2 is located at the surface certain altitude of glass carrier bench 3, the described mouth of pipe face of dropper 7 carries glass
The position of slide 8 set on platform outer shroud 302.Steam caused by heating water tank 4 heats slide 8 by glass carrier bench 3, that is, is adding
Suitable time is fumigated in the presence of hot water storgae 4.Therefore the present apparatus can unify drop piece height, can be to the dye on every slide
Colour solid division phase density control effectively.After a slide drop piece terminates, rotate outer shroud 302 and place next slide
8, and aligned with arrow 6, multiple slides 8 can be placed.So as to simultaneously handle and fumigate multiple slides, save manpower and
Time, reach the effect of batch processing.Cell suspension is dropped on slide, excessive moisture can flow into interior table top 301, and cell is stagnant
Stay on slide, caused waste liquid flows out from scupper 5, so as to further to the chromosome separation phase density on every slide
It control effectively.
General principle of the present utility model, principal character and advantage has been shown and described above, it is new not departing from this practicality
On the premise of type spirit and scope, the utility model also has various changes and modifications, and these changes and improvements both fall within requirement and protected
The scope of the utility model of shield.
Claims (5)
1. a kind of drop piece instrument of chromosome karyotype analysis sample, including support (1), adjustable dropper geometrical clamp (2), rotatable load
Glass platform (3) and heating water tank (4), it is characterised in that described support (1) is fixed in heating water tank (4) vertically, from glass carrier bench
(3) run through among；Dropper geometrical clamp (2) is horizontally fixed on support (1), directly over glass carrier bench (3)；Described glass carrier bench
(3) it is in groove-like, is made up of two parts of interior table top (301) and outer shroud (302), interior table top (301) and outer shroud (302) is relatively embedding
Close and connect, rotated within outer shroud (302) centered on table top (301), mark has alignment arrow (6) on interior table top (301)；
The heating rod (402) that described heating water tank (4) includes cell body (401) and cell body (401) bottom is set；Described dropper is fixed
Dropper (7) is provided with folder (2).
A kind of 2. drop piece instrument of chromosome karyotype analysis sample according to claim 1, it is characterised in that described dropper
Geometrical clamp (2) passes through connecting rod by dropper jig arm (201), dropper adjusting nut (202), dropper geometrical clamp adjusting nut (203)
(204) form, by rotating dropper geometrical clamp adjusting nut (203), dropper geometrical clamp (2) is slided along support (1) vertical direction
It is dynamic, so as to adjust height of the dropper geometrical clamp (2) relative to glass carrier bench (3).
A kind of 3. drop piece instrument of chromosome karyotype analysis sample according to claim 1, it is characterised in that described load glass
For platform outer shroud (302) with interior table top (301) into angle, the angle number of degrees are 130 ° -170 °.
A kind of 4. drop piece instrument of chromosome karyotype analysis sample according to claim 1, it is characterised in that described load glass
In platform on table top (301), scupper (5) is being set close to outer shroud (302) place.
A kind of 5. drop piece instrument of chromosome karyotype analysis sample according to claim 2, it is characterised in that described dropper
Geometrical clamp (2) adjusts the dropper (7) that dropper jig arm (201) adds different size by rotating dropper adjusting nut (202).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720390313.1U CN206656896U (en) | 2017-04-14 | 2017-04-14 | A kind of drop piece instrument of chromosome karyotype analysis sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720390313.1U CN206656896U (en) | 2017-04-14 | 2017-04-14 | A kind of drop piece instrument of chromosome karyotype analysis sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206656896U true CN206656896U (en) | 2017-11-21 |
Family
ID=60318442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720390313.1U Expired - Fee Related CN206656896U (en) | 2017-04-14 | 2017-04-14 | A kind of drop piece instrument of chromosome karyotype analysis sample |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206656896U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114184438A (en) * | 2020-09-14 | 2022-03-15 | 长春理工大学 | Device and method for extracting chromosome |
-
2017
- 2017-04-14 CN CN201720390313.1U patent/CN206656896U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114184438A (en) * | 2020-09-14 | 2022-03-15 | 长春理工大学 | Device and method for extracting chromosome |
| CN114184438B (en) * | 2020-09-14 | 2024-05-10 | 长春理工大学 | Chromosome extraction device and method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20171121 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |