CN208500910U - A kind of instrument for extracting nucleic acid - Google Patents

A kind of instrument for extracting nucleic acid Download PDF

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Publication number
CN208500910U
CN208500910U CN201820100393.7U CN201820100393U CN208500910U CN 208500910 U CN208500910 U CN 208500910U CN 201820100393 U CN201820100393 U CN 201820100393U CN 208500910 U CN208500910 U CN 208500910U
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China
Prior art keywords
bar magnet
guide rail
fuselage
nucleic acid
instrument
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CN201820100393.7U
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Chinese (zh)
Inventor
周志图
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Wuxi Hundred Biotechnology Co Ltd
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Wuxi Hundred Biotechnology Co Ltd
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Abstract

The utility model provides a kind of instrument for extracting nucleic acid, including fuselage, magnetic frame, bar magnet, bar magnet stock, bar magnet set, drip deflector, deep-well plates, positioning seat, turntable, control panel.Wherein, guide rail is provided in the vertical direction of the fuselage, the guide rail includes the first guide rail and the second guide rail, and first guide rail and second guide rail are parallel on the fuselage.By the way that the control panel can electrodeless adjustment vibrates, the speed of mixing and magnetic, the magnetic frame and the bar magnet stock are double mode, the deep-well plates are common deep-well plates.By the utility model with solve the problems, such as instrument for extracting nucleic acid bar magnet positional shift of the existing technology, calibration frequently, operating mode is single, deep-well plates waste, is unable to accurately control oscillation, mixing, magnetic speed.

Description

A kind of instrument for extracting nucleic acid
Technical field
The utility model relates to a kind of nucleic acid extraction fields, and in particular to a kind of instrument for extracting nucleic acid.
Background technique
Nucleic acids research is modern biology, the important topic in medical research.Carrier of the nucleic acid as hereditary information be The material base of gene expression, in addition to normally grow in organism, develop and breed etc. in vital movements have it is particularly significant Effect outside, the abnormal conditions of it and life, such as tumour generation, radiation insult, genetic disease also have substantial connection.
Instrument for extracting nucleic acid is the instrument that the extraction work of sample nucleic acid is automatically performed using matched nucleic acid extracting reagent Device, instrument for extracting nucleic acid are divided into two classes: one kind is large-scale automation, commonly referred to as automated fluid work station;Another kind of is small The automatic instrument for extracting nucleic acid of type is automatically performed extraction purification process using packaged matched reagent.Large-scale automated fluid work station Because equipment cost is high, operating cost is high, is suitble to once extract thousands of a one species samples, so be really applied It is fewer.And the instrument of small automatic, it is easy to operate to be widely used because instrument and equipment and operating cost are low.
Currently, the following defects and deficiencies exist for common instrument for extracting nucleic acid in the market: (1) track of magnetic frame is single track Road, it is fixed unstable, it be easy to cause magnetic bar position deviation occur, need to often calibrate;(2) oscillation, mixing and magnetic speed can not It adjusts, or can only adjust fast, slow, be unfavorable for optimizing for different samples;(3) matched deep-well plates can not flexible modulation Flux will cause the waste of 96 hole deep-well plates, increase cost when the sample size of processing is less;(4) type of magnetic bar It number can not change, pattern switching can not be carried out, when sample pipetting volume volume to be treated is excessive, experiment can not be flexibly met and want It asks.
Utility model content
The utility model provides a kind of instrument for extracting nucleic acid, inclined to solve instrument for extracting nucleic acid bar magnet of the existing technology position It moves, the problem that calibration is frequent, operating mode is single.
In order to solve the above technical problems, the utility model provides a kind of instrument for extracting nucleic acid, including fuselage, magnetic frame, bar magnet, Bar magnet stock, bar magnet set, drip deflector, deep-well plates, positioning seat, turntable, control panel.Wherein, the vertical direction of the fuselage On be provided with guide rail, the magnetic frame and the bar magnet stock are arranged on the guide rail and the magnetic frame is located at the bar magnet The lower section on the fuselage and being located at the bar magnet stock is arranged in the top of stock, the drip deflector.The bar magnet setting On the magnetic frame, the bar magnet is set on the bar magnet stock.The turntable is close in the fuselage and can be certainly By rotating, it is fixed on the turntable on the positioning seat and the positioning seat and is placed with the deep-well plates, the control panel Side of the fuselage relative to the magnetic frame is set.The guide rail include the first guide rail and the second guide rail, described first Guide rail and second guide rail are parallel on the fuselage.By the control panel can step-less adjustment oscillation, mixing and The speed of magnetic, the magnetic frame and the bar magnet stock are double mode, and the deep-well plates are common deep-well plates.
Preferably, the drip deflector is hinged on the fuselage and can move along the horizontal plane.
Preferably, the common deep-well plates include pedestal, groove, cutting, and the pedestal can be fitted on positioning seat, described It is provided with the groove on pedestal and the cutting can be placed in the groove.
Preferably, it is provided with 6 positioning seats on the turntable, and is arranged on any two adjacent positioning seats There is heating and cooling module.
Preferably, the turntable center is provided with conducting ring, the heating and cooling module by the conducting ring with it is described Control system connection on fuselage.
Preferably, the double mode is high-throughput mode and large capacity mode.
Preferably, the high-throughput mode is to be provided with 96 bar magnets on the magnetic frame and according to 12 × 8 rows It arranges, 96 bar magnets sets are provided on the bar magnet stock and are arranged according to 12 × 8, single hole volume is 2.2ml.
Preferably, the large capacity mode is to be provided with 24 bar magnets on the magnetic frame and arrange according to 6 × 4, It is provided with 24 bar magnet sets on the bar magnet stock and is arranged according to 6 × 4, single hole volume is 11ml.
The utility model bring passes through setting double track the utility model has the advantages that a kind of instrument for extracting nucleic acid provided by the utility model Road keeps magnetic frame and bar magnet stock very steady when moving up and down, and is not in shake, when primary calibration can guarantee long Between position accuracy.Magnetic frame and bar magnet stock are double mode, can be used according to the size of sample pipetting volume volume different Mode.Deep-well plates are common deep-well plates, can be avoided according to the quantity of sample, the quantity of flexible choice cutting using high pass The waste of deep-well plates, reduces experimental cost when amount mode.
Detailed description of the invention
Fig. 1 is the overall structure diagram according to the instrument for extracting nucleic acid of the utility model embodiment.
Fig. 2 is the structural schematic diagram according to the common deep-well plates of the utility model embodiment.
Wherein, 1- fuselage, 2- magnetic frame, 3- bar magnet, 4- bar magnet stock, 5- bar magnet set, 6- drip deflector, 7- deep-well plates, 701- pedestal, 702- groove, 703- cutting, 8- positioning seat, 9- turntable, 10- heating and cooling module.
Specific embodiment
To keep the purpose of this utility model, technical solution and advantage clearer, below in conjunction with drawings and the specific embodiments, The utility model is described in further detail.
Fig. 1 is the overall structure diagram according to the instrument for extracting nucleic acid of the utility model embodiment.Fig. 2 is practical according to this The structural schematic diagram of the common deep-well plates of new embodiment.
First embodiment:
A kind of instrument for extracting nucleic acid provided by the utility model, including fuselage 1, magnetic frame 2, bar magnet 3, bar magnet stock 4, bar magnet Cover 5, drip deflector 6, deep-well plates 7, positioning seat 8, turntable 9, control panel.Wherein, it is provided in the vertical direction of the fuselage 1 Guide rail, the magnetic frame 2 and the bar magnet stock 4 are arranged on the guide rail and the magnetic frame 2 is located at the bar magnet stock 4 Top, the drip deflector 6 is arranged on the fuselage 1 and is located at the lower section of the bar magnet stock 4.The bar magnet 3 is arranged On the magnetic frame 2, the bar magnet set 5 is arranged on the bar magnet stock 4.The turntable 9 be close in the fuselage 1 and It can be freely rotated, be fixed on the turntable 9 on the positioning seat 8 and the positioning seat 8 and be placed with the deep-well plates 7, institute It states control panel and side of the fuselage 1 relative to the magnetic frame 2 is set.The guide rail includes that the first guide rail and second is led Rail, first guide rail and second guide rail are parallel on the fuselage 1.The magnetic frame 2 and the bar magnet stock 4 It can be securely fixed on first guide rail and second guide rail, the magnetic frame 2 and the bar magnet stock 4 are upper and lower It is very steady when mobile, it is not in shake, primary calibration can guarantee the accuracy of long-time position.Pass through the control Panel can step-less adjustment oscillation, mixing and the speed of magnetic keep speed more accurate using intelligent speed-regulating, be conducive to user's root Adjustment is optimized according to sample and magnetic bead situation.The magnetic frame 2 and the bar magnet stock 4 are double mode, can be according to sample The size of injection volume uses different modes.The deep-well plates 7 are common deep-well plates, can be according to the quantity of sample, flexibly The quantity for selecting cutting, the waste of the deep-well plates 7, reduces experimental cost when avoiding using high-throughput mode.
Furthermore, the drip deflector 6 is hinged on the fuselage 1 and can move along the horizontal plane.The common depth Orifice plate includes pedestal 701, groove 702, cutting 703, and the pedestal 701 can be fitted on positioning seat 8, is set on the pedestal 701 It is equipped with the groove and the cutting 703 can be placed in the groove 702.6 positioning are provided on the turntable 9 Seat 8, and heating and cooling module 10 is provided on any two adjacent positioning seats 8.9 center of turntable is provided with conduction Ring, the heating and cooling module 10 are connect by the conducting ring with the control system on the fuselage 1.
In the present embodiment, using high-throughput mode, the high throughput mode is is provided with 96 institutes on the magnetic frame 2 It states bar magnet 3 and is arranged according to 12 × 8,96 bar magnets sets 5 are provided on the bar magnet stock 4 and according to 12 × 8 arrangements, list Pore volume is 2.2ml.
Second embodiment:
A kind of instrument for extracting nucleic acid provided by the utility model, including fuselage 1, magnetic frame 2, bar magnet 3, bar magnet stock 4, bar magnet Cover 5, drip deflector 6, deep-well plates 7, positioning seat 8, turntable 9, control panel.Wherein, it is provided in the vertical direction of the fuselage 1 Guide rail, the magnetic frame 2 and the bar magnet stock 4 are arranged on the guide rail and the magnetic frame 2 is located at the bar magnet stock 4 Top, the drip deflector 6 is arranged on the fuselage 1 and is located at the lower section of the bar magnet stock 4.The bar magnet 3 is arranged On the magnetic frame 2, the bar magnet set 5 is arranged on the bar magnet stock 4.The turntable 9 be close in the fuselage 1 and It can be freely rotated, be fixed on the turntable 9 on the positioning seat 8 and the positioning seat 8 and be placed with the deep-well plates 7, institute It states control panel and side of the fuselage 1 relative to the magnetic frame 2 is set.The guide rail includes that the first guide rail and second is led Rail, first guide rail and second guide rail are parallel on the fuselage 1.The magnetic frame 2 and the bar magnet stock 4 It can be securely fixed on first guide rail and second guide rail, the magnetic frame 2 and the bar magnet stock 4 are upper and lower It is very steady when mobile, it is not in shake, primary calibration can guarantee the accuracy of long-time position.Pass through the control Panel can step-less adjustment oscillation, mixing and the speed of magnetic keep speed more accurate using intelligent speed-regulating, be conducive to user's root Adjustment is optimized according to sample and magnetic bead situation.The magnetic frame 2 and the bar magnet stock 4 are double mode, can be according to sample The size of injection volume uses different modes.The deep-well plates 7 are common deep-well plates, can be according to the quantity of sample, flexibly The quantity for selecting cutting, the waste of the deep-well plates 7, reduces experimental cost when avoiding using high-throughput mode.
Furthermore, the drip deflector 6 is hinged on the fuselage 1 and can move along the horizontal plane.The common depth Orifice plate includes pedestal 701, groove 702, cutting 703, and the pedestal 701 can be fitted on positioning seat 8, is set on the pedestal 701 It is equipped with the groove and the cutting 703 can be placed in the groove 702.6 positioning are provided on the turntable 9 Seat 8, and heating and cooling module 10 is provided on any two adjacent positioning seats 8.9 center of turntable is provided with conduction Ring, the heating and cooling module 10 are connect by the conducting ring with the control system on the fuselage 1.
In the present embodiment, using large capacity mode, the large capacity mode is is provided with 24 institutes on the magnetic frame 2 It states bar magnet 3 and is arranged according to 6 × 4,24 bar magnets sets 5 are provided on the bar magnet stock 4 and according to 6 × 4 arrangements, single hole Volume is 11ml.
In conclusion a kind of instrument for extracting nucleic acid provided by the utility model, makes magnetic frame and bar magnet by the way that two-orbit is arranged Stock is very steady when moving up and down, and is not in shake, primary calibration can guarantee the accuracy of long-time position.Magnetic Power frame and bar magnet stock are double mode, can use different modes according to the size of sample pipetting volume volume.Deep-well plates are common Deep-well plates can avoid the wave using deep-well plates when high-throughput mode according to the quantity of sample, the quantity of flexible choice cutting Take, reduces experimental cost.
The above description is only the embodiments of the present invention, is not intended to limit the utility model, for this field Technical staff for, various modifications and changes may be made to the present invention.Within the spirit and principle of the utility model, Any modification, equivalent replacement, improvement and so on should be included within the scope of the claims of the utility model.

Claims (8)

1. a kind of instrument for extracting nucleic acid, including fuselage (1), magnetic frame (2), bar magnet (3), bar magnet stock (4), bar magnet set (5), dropping liquid Baffle (6), deep-well plates (7), positioning seat (8), turntable (9), control panel are provided in the vertical direction of the fuselage (1) and lead Rail, the magnetic frame (2) and the bar magnet stock (4) are arranged on the guide rail and the magnetic frame (2) is located at the bar magnet The top of stock (4), the drip deflector (6) are arranged on the fuselage (1) and are located at the lower section of the bar magnet stock (4), The bar magnet (3) is arranged on the magnetic frame (2), and the bar magnet set (5) is arranged on the bar magnet stock (4), and described turn Disk (9) is close in the fuselage (1) and can be freely rotated, and the positioning seat (8) and described fixed is fixed on the turntable (9) It is placed with the deep-well plates (7) on position seat (8), the control panel is arranged in the fuselage (1) relative to the magnetic frame (2) Side, which is characterized in that the guide rail includes the first guide rail and the second guide rail, and first guide rail and second guide rail are flat Row be arranged on the fuselage (1), by the control panel can step-less adjustment oscillation, mixing and magnetic speed, the magnetic Power frame (2) and the bar magnet stock (4) are double mode, and the deep-well plates (7) are common deep-well plates.
2. instrument for extracting nucleic acid as described in claim 1, which is characterized in that the drip deflector (6) is hinged on the fuselage (1) It can move above and along the horizontal plane.
3. instrument for extracting nucleic acid as described in claim 1, which is characterized in that the common deep-well plates include pedestal (701), groove (702), cutting (703), the pedestal (701) can be fitted on positioning seat (8), be provided on the pedestal (701) described recessed Slot and the cutting (703) can be placed in the groove (702).
4. instrument for extracting nucleic acid as described in claim 1, which is characterized in that be provided with 6 positioning seats on the turntable (9) (8), heating and cooling module (10) and on any two adjacent positioning seats (8) are provided with.
5. instrument for extracting nucleic acid as claimed in claim 4, which is characterized in that turntable (9) center is provided with conducting ring, described Heating and cooling module (10) is connect by the conducting ring with the control system on the fuselage (1).
6. the instrument for extracting nucleic acid as described in Claims 1 to 5 is any, which is characterized in that the double mode be high-throughput mode and Large capacity mode.
7. instrument for extracting nucleic acid as claimed in claim 6, which is characterized in that the high throughput mode is on the magnetic frame (2) It is provided with 96 bar magnets (3) and is arranged according to 12 × 8, be provided with 96 bar magnet sets (5) on the bar magnet stock (4) And according to 12 × 8 arrangements, single hole volume is 2.2ml.
8. instrument for extracting nucleic acid as claimed in claim 6, which is characterized in that the large capacity mode is on the magnetic frame (2) It is provided with 24 bar magnets (3) and is arranged according to 6 × 4, be provided with 24 bar magnet sets (5) on the bar magnet stock (4) And according to 6 × 4 arrangements, single hole volume is 11ml.
CN201820100393.7U 2018-01-22 2018-01-22 A kind of instrument for extracting nucleic acid Active CN208500910U (en)

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Application Number Priority Date Filing Date Title
CN201820100393.7U CN208500910U (en) 2018-01-22 2018-01-22 A kind of instrument for extracting nucleic acid

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Application Number Priority Date Filing Date Title
CN201820100393.7U CN208500910U (en) 2018-01-22 2018-01-22 A kind of instrument for extracting nucleic acid

Publications (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107974394A (en) * 2018-01-22 2018-05-01 无锡百泰克生物技术有限公司 A kind of instrument for extracting nucleic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107974394A (en) * 2018-01-22 2018-05-01 无锡百泰克生物技术有限公司 A kind of instrument for extracting nucleic acid

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