CN208440647U - A kind of cell cultivation instrument for immune cell expansion - Google Patents
A kind of cell cultivation instrument for immune cell expansion Download PDFInfo
- Publication number
- CN208440647U CN208440647U CN201820978967.0U CN201820978967U CN208440647U CN 208440647 U CN208440647 U CN 208440647U CN 201820978967 U CN201820978967 U CN 201820978967U CN 208440647 U CN208440647 U CN 208440647U
- Authority
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- China
- Prior art keywords
- cabinet
- immune cell
- heat
- water jacket
- cell expansion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000010261 cell growth Effects 0.000 title claims abstract description 21
- 210000002865 immune cell Anatomy 0.000 title claims abstract description 21
- 238000004113 cell culture Methods 0.000 title claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 39
- 238000004321 preservation Methods 0.000 claims abstract description 28
- 238000009413 insulation Methods 0.000 claims abstract description 19
- 238000002347 injection Methods 0.000 claims description 9
- 239000007924 injection Substances 0.000 claims description 9
- 229910001220 stainless steel Inorganic materials 0.000 claims description 8
- 239000010935 stainless steel Substances 0.000 claims description 8
- 238000001914 filtration Methods 0.000 claims description 2
- 239000006260 foam Substances 0.000 claims description 2
- 239000003365 glass fiber Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 230000001105 regulatory effect Effects 0.000 claims description 2
- 238000007789 sealing Methods 0.000 claims description 2
- 239000005341 toughened glass Substances 0.000 claims description 2
- 230000017525 heat dissipation Effects 0.000 abstract description 4
- 210000004027 cell Anatomy 0.000 abstract description 3
- 230000003321 amplification Effects 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 230000006872 improvement Effects 0.000 description 7
- 238000005516 engineering process Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000008236 heating water Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000008223 sterile water Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 210000004443 dendritic cell Anatomy 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
Landscapes
- Mushroom Cultivation (AREA)
- Cultivation Of Plants (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model provides a kind of cell cultivation instrument for immune cell expansion, belongs to biological culture field, including cabinet;External door is arranged in the cabinet overhead surface setting information control centre, underlying surfaces;Inside door is set inside the external door;Thermal insulation layer is arranged in the cabinet lower outer;The thermal insulation layer inner tight wraps up water jacket layer;Exhaust fan is set on the left of the cabinet lower backside, and CO interface is arranged in right side;The water jacket layer inner tight wraps up heat-preservation liner;Temperature sensor is arranged in the heat-preservation liner top front, and CO concentration sensor is arranged in top;Battery is arranged in the cabinet upper interior;Heater is set among the water jacket layer;The utility model passes through multiple independent wickets on setting inside door, prevent box house atmosphere from generating larger fluctuation, heater ensures that box interior temperature is constant, exhaust fan carries out the exchange of cabinet inner air and outer air and heat dissipation, box house atmosphere remains unchanged when battery ensures power-off, ensures cell amplification cultivation.
Description
Technical field
The utility model relates to a kind of culture apparatus, specifically a kind of cell cultivation instrument for immune cell expansion.
Background technique
Immunocyte is commonly called as leucocyte, refers to and participates in immune response or cell relevant to immune response, including lymph is thin
Born of the same parents, Dendritic Cells, Monocytes/Macrophages, granulocyte, mast cell etc., immunocyte are responsible for important angle in human body
Color;Immune cell expansion technology is by the artificial some factors of addition, biological agent and Chinese prescription etc., in vivo and in vitro
Reach the increased process of immunocyte quantity, the activity and differentiation capability of immunocyte are improved while quantity increases, from
And better curative effect is played, make it the various diseases for preferably treating the mankind;
Immune cell expansion technology is the advanced cell preparation techniques of current domestic regeneration biological medical industries, is that China is big
Power helps the sophisticated technology of the biological medicine technology modern service industry of development, while being also the doctor having under high-tech brace foundation
Treat innovation mode;China is populous nation, and various major diseases have a high-incidence record in China, immune cell expansion technology at
Fruit will directly benefit those " incurable disease " patients being almost identified to be had to improving the physique of the entire people, optimizing population structure
Extremely important meaning.
For temperature and humidity, CO in thin incubation2Concentration is more demanding, and immunocyte culture apparatus currently on the market is only
It can be carried out simple control operation, do not have the ability similar to the emergencies processing such as power-off, overheat.
Utility model content
In view of the above shortcomings of the prior art, the technical problem to be solved by the present invention is to provide a kind of thermal insulation properties
The cell cultivation instrument for immune cell expansion that is good, preventing parameter fluctuation, warning function.
In order to solve the above technical problems, the utility model provides following technical solution:
A kind of cell cultivation instrument for immune cell expansion, including cabinet, information control center, external door, inside door, adjusting
Leg, thermal insulation layer, water jacket layer, heat-preservation liner, exhaust fan, filter screen, water injection hole, drainage hole, stainless steel humidification disk, temperature sensing
Device, CO2Concentration sensor, UV lamp, battery, shelf, attaching plug, heater, alarm, CO2Flow controller, CO2It connects
Mouthful;External door is arranged in the cabinet overhead surface setting information control centre, underlying surfaces, and bottom setting adjusts leg;The information
Alarm is arranged in the control centre upper right corner;Inside door is set inside the external door;Thermal insulation layer is arranged in the cabinet lower outer;It is described
Thermal insulation layer inner tight wraps up water jacket layer;Water injection hole is set above the water jacket layer, and drainage hole, inner tight package is arranged in lower section
Heat-preservation liner;Exhaust fan is set on the left of the cabinet lower backside, and CO is arranged in right side2Interface;It was arranged on the outside of the exhaust fan
Strainer;The heat-preservation liner bottom plate setting stainless steel humidification disk, top front are arranged temperature sensor, CO are arranged in top2It is dense
Sensor is spent, UV lamp, centre setting step shelf is arranged in top rear;Battery is arranged in the cabinet upper interior, and the back side is set
Set attaching plug;Heater is set among the water jacket layer;The CO2CO is set on the right side of interface2Flow controller.
As the further improvement project of the utility model: the external door fills floride-free foam insulation.
As the further improvement project of the utility model: multiple individually operated wickets are opened up on the inside door, it is whole
Material uses tempered glass.
As the further improvement project of the utility model: the cabinet, external door and inside door edge are respectively provided with magnetic strip of paper used for sealing.
As the further improvement project of the utility model: stuffed heat insulated glass fibers of good performance inside the thermal insulation layer
Dimension.
As the further improvement project of the utility model: the exhaust fan uses super-silent fan, and fan uses basis
The speed regulating motor of service condition control revolving speed.
As the further improvement project of the utility model: the filter screen uses efficient HEPA filter screen.
As the utility model further improvement project: the heater uses thermistor.
Compared with prior art, the utility model has the beneficial effects that
The utility model is prevented box house atmosphere from generating larger fluctuation, is added by the inside door of the multiple independent wickets of setting
Water in hot device heating water jacket layer, keeps the temperature box house, exhaust fan carries out the exchange of cabinet inner air and outer air and heat dissipation, electric power storage
Pond ensures under power blackout situation that case body equipment runs well, and guarantees that box house atmosphere remains unchanged, ensures cell cultivation process not
It is impacted.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of cell cultivation instrument for immune cell expansion;
Fig. 2 is the structural schematic diagram in a kind of cell cultivation instrument for immune cell expansion inside front;
Fig. 3 is a kind of structural schematic diagram of lateral inner in cell cultivation instrument for immune cell expansion;
In figure: 1- cabinet, 2- information control center, 3- external door, 4- inside door, 5- adjust leg, 6- thermal insulation layer, 7- water jacket layer,
8- heat-preservation liner, 9- exhaust fan, 10- filter screen, 11- water injection hole, 12- drainage hole, 13- humidification disk, 14- temperature sensor, 15-
CO2Sensor, 16-UV lamp, 17- battery, 18- shelf, 19- attaching plug, 20- heater, 21- alarm, 22- CO2Stream
Amount controller, 23- CO2Interface.
Specific embodiment
The technical solution of the patent is explained in further detail With reference to embodiment.
The embodiment of this patent is described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning to end
Same or similar label indicates same or similar element or element with the same or similar functions.Below with reference to attached
The embodiment of figure description is exemplary, and is only used for explaining this patent, and cannot be understood as a limitation of this patent.
In the description of this patent, it is to be understood that term " center ", "upper", "lower", "front", "rear", " left side ",
The orientation or positional relationship of the instructions such as " right side ", "vertical", "horizontal", "top", "bottom", "inner", "outside" is based on the figure
Orientation or positional relationship, be merely for convenience of description this patent and simplify description, rather than the device of indication or suggestion meaning or
Element must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as the limitation to this patent.
In the description of this patent, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection ", " setting " shall be understood in a broad sense, for example, it may be being fixedly linked, being arranged, may be a detachable connection, set
It sets, or is integrally connected, is arranged.For the ordinary skill in the art, above-mentioned art can be understood as the case may be
The concrete meaning of language in this patent.
Fig. 1-3 is please referred to, present embodiments provides a kind of cell cultivation instrument for immune cell expansion, including cabinet 1,
Information control center 2, external door 3, inside door 4, adjust leg 5, thermal insulation layer 6, water jacket layer 7, heat-preservation liner 8, exhaust fan 9, filter screen 10,
Water injection hole 11, drainage hole 12, stainless steel humidification disk 13, temperature sensor 14, CO2Concentration sensor 15, UV lamp 16, battery
17, shelf 18, attaching plug 19, heater 20, alarm 21, CO2Flow controller 22, CO2Interface 23;1 top of cabinet
External door 3 is arranged in surface setting information control centre 2, underlying surfaces, and bottom setting adjusts leg 5;2 upper right of information control center
Alarm 21 is arranged in angle;Inside door 4 is set inside the external door 3;Thermal insulation layer 6 is arranged in 1 lower outer of cabinet;The thermal insulation layer
6 inner tights wrap up water jacket layer 7;Water injection hole 11 is set above the water jacket layer 7, and drainage hole 12, inner tight packet is arranged in lower section
Wrap up in heat-preservation liner 8;Exhaust fan 9 is set on the left of 1 lower backside of cabinet, and CO is arranged in right side2Interface 23;Outside the exhaust fan 9
Filter screen 10 is arranged in side;Temperature sensor 14 is arranged in 8 bottom plate of the heat-preservation liner setting stainless steel humidification disk 13, top front,
CO is set in top2UV lamp 16, centre setting step shelf 18 is arranged in concentration sensor 15, top rear;1 top of cabinet
Inside setting battery 17, attaching plug 19 is arranged in the back side;Heater 20 is set among the water jacket layer 7;The CO2Interface 23
CO is arranged in right side2Flow controller 22;The condition of culture inside cabinet 1 can be preset on information control center 2, multiple independences are small
The inside door 4 of door facilitates progress individually operated, prevents 1 inside atmosphere of cabinet from generating larger fluctuation, thermal insulation layer 6, water jacket layer 7, heat preservation
8 three-decker of liner can effectively carry out insulation;Exhaust fan 9 carries out the air exchange and heat dissipation in heat-preservation liner 8, filtering
Net 10 ensures air cleaning in heat-preservation liner 8;It is filled the water from water injection hole 11 into water jacket layer 7, CO2Interface 23 is into heat-preservation liner 8
It is passed through CO2, water in heater 20 heating water jacket layer 7, water temperature is radiated to temperature in heat-preservation liner 8, temperature sensing in water jacket layer 7
Device 14 incudes the temperature in heat-preservation liner 8, CO2Concentration sensor 15 incudes CO in heat-preservation liner 82Concentration, CO2Flow controller
22 ensure the CO in heat-preservation liner 82Concentration, stainless steel be humidified disk 13 on sterile water keep heat-preservation liner 8 in humidity, normally
In the case of by attaching plug 19 access alternating current work, under power blackout situation by battery 17 ensure operate normally;
The working principle of the utility model is: immunocyte is put into before cultivating inside cabinet 1, UV lamp 16 is first opened, it is right
Carry out sterilization processing inside cabinet 1, after the completion of sterilization, preset condition of culture on information control center 2, from water injection hole 11 to
It is filled the water in water jacket layer 7, CO2Interface 23 is passed through CO into heat-preservation liner 82, water in heater 20 heating water jacket layer 7, water jacket layer 7
Middle water temperature is radiated to temperature in heat-preservation liner 8, and temperature sensor 14 incudes the temperature in heat-preservation liner 8, CO2Concentration sensor 15
Incude CO in heat-preservation liner 82Concentration, exhaust fan 9 carry out the air exchange and heat dissipation in heat-preservation liner 8, CO2Flow controller 22
Ensure the CO in heat-preservation liner 82Concentration, stainless steel be humidified disk 13 on sterile water keep heat-preservation liner 8 in humidity, positive reason
Alternating current is accessed by attaching plug 19 under condition to work, and is ensured and is operated normally by battery 17 under power blackout situation.
The preferred embodiment of the patent is described in detail above, but this patent is not limited to above-mentioned embodiment party
Formula within the knowledge of one of ordinary skill in the art can also be under the premise of not departing from this patent objective
It makes a variety of changes.
Claims (8)
1. a kind of cell cultivation instrument for immune cell expansion, including it is cabinet (1), information control center (2), external door (3), interior
Door (4) adjusts leg (5), thermal insulation layer (6), water jacket layer (7), heat-preservation liner (8), exhaust fan (9), filter screen (10), water injection hole
(11), drainage hole (12), stainless steel humidification disk (13), temperature sensor (14), CO2Concentration sensor (15), stores UV lamp (16)
Battery (17), shelf (18), attaching plug (19), heater (20), alarm (21), CO2Flow controller (22), CO2Interface
(23);It is characterized in that: cabinet (1) the overhead surface setting information control centre (2), external door (3) are arranged in underlying surfaces, bottom
Setting adjusts leg (5);Alarm (21) are arranged in information control center (2) upper right corner;Inside door is set inside the external door (3)
(4);Thermal insulation layer (6) are arranged in cabinet (1) lower outer;Thermal insulation layer (6) inner tight wraps up water jacket layer (7);It is described
Water injection hole (11) are set above water jacket layer (7), drainage hole (12) are arranged in lower section, and inner tight wraps up heat-preservation liner (8);The case
Exhaust fan (9) are set on the left of body (1) lower backside, CO is arranged in right side2Interface (23);Setting filtering on the outside of the exhaust fan (9)
Net (10);Heat-preservation liner (8) the bottom plate setting stainless steel is humidified disk (13), and temperature sensor (14) are arranged in top front, top
CO is set in portion2UV lamp (16) are arranged in concentration sensor (15), top rear, centre setting step shelf (18);The cabinet
(1) attaching plug (19) are arranged in upper interior setting battery (17), the back side;Heater is set among the water jacket layer (7)
(20);The CO2CO is set on the right side of interface (23)2Flow controller (22).
2. a kind of cell cultivation instrument for immune cell expansion according to claim 1, it is characterized in that: the external door
(3) floride-free foam insulation is filled.
3. a kind of cell cultivation instrument for immune cell expansion according to claim 1, it is characterized in that: the inside door
(4) multiple individually operated wickets are opened up on, overall material uses tempered glass.
4. a kind of cell cultivation instrument for immune cell expansion according to claim 1 or 2 or 3, it is characterized in that: described
Cabinet (1), external door (3) and inside door (4) edge are respectively provided with magnetic strip of paper used for sealing.
5. a kind of cell cultivation instrument for immune cell expansion according to claim 1, it is characterized in that: the thermal insulation layer
(6) internal stuffed heat insulated glass fibre of good performance.
6. a kind of cell cultivation instrument for immune cell expansion according to claim 1, it is characterized in that: the exhaust fan
(9) super-silent fan is used, fan uses the speed regulating motor that revolving speed is controlled according to service condition.
7. a kind of cell cultivation instrument for immune cell expansion according to claim 1, it is characterized in that: the filter screen
Using efficient HEPA filter screen.
8. a kind of cell cultivation instrument for immune cell expansion according to claim 1, it is characterized in that: the heater
(20) thermistor is used.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201820978967.0U CN208440647U (en) | 2018-06-25 | 2018-06-25 | A kind of cell cultivation instrument for immune cell expansion |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201820978967.0U CN208440647U (en) | 2018-06-25 | 2018-06-25 | A kind of cell cultivation instrument for immune cell expansion |
Publications (1)
Publication Number | Publication Date |
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CN208440647U true CN208440647U (en) | 2019-01-29 |
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ID=65089253
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CN201820978967.0U Expired - Fee Related CN208440647U (en) | 2018-06-25 | 2018-06-25 | A kind of cell cultivation instrument for immune cell expansion |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112481129A (en) * | 2021-01-15 | 2021-03-12 | 北京图腾猎技科技有限公司 | Cell culture instrument for immune cell amplification |
-
2018
- 2018-06-25 CN CN201820978967.0U patent/CN208440647U/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112481129A (en) * | 2021-01-15 | 2021-03-12 | 北京图腾猎技科技有限公司 | Cell culture instrument for immune cell amplification |
CN112481129B (en) * | 2021-01-15 | 2021-07-09 | 北京达济康华生物科技有限责任公司 | Cell culture instrument for immune cell amplification |
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Legal Events
Date | Code | Title | Description |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190129 |