CN208373079U - A kind of erythromycin side chain synthesis special reactor - Google Patents
A kind of erythromycin side chain synthesis special reactor Download PDFInfo
- Publication number
- CN208373079U CN208373079U CN201820624706.9U CN201820624706U CN208373079U CN 208373079 U CN208373079 U CN 208373079U CN 201820624706 U CN201820624706 U CN 201820624706U CN 208373079 U CN208373079 U CN 208373079U
- Authority
- CN
- China
- Prior art keywords
- fixedly connected
- erythromycin
- kettle cover
- autoclave body
- side chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
The utility model discloses a kind of erythromycin side chains to synthesize special reactor, including autoclave body, the autoclave body top movable is connected with kettle cover, annulus is fixedly connected on the inner wall of the autoclave body, the upper surface of the annulus is connected with rubber spacer, disk is fixedly connected at the top of the rubber spacer, the upper surface fixation of the disk is inlaid with first bearing, the inner surface of the first bearing is fixedly connected with agitating shaft, the surface of the agitating shaft is fixedly connected with stirring rod, and stirring rod is located at the inside of autoclave body, the surface of the kettle cover is fixedly connected with electric machine support, servo motor is fixedly connected at the top of the electric machine support, the surface fixation of the kettle cover is inlaid with second bearing.The utility model solves when detecting the response situation of erythromycin side chain by setting disk, hexagonal inserted link and feeding device, opens reaction kettle, not only will affect the leakproofness of reaction kettle, but also open the problem of reaction kettle kettle cover is also more troublesome.
Description
Technical field
The utility model relates to erythromycin side chain synthesis device technical field, specially a kind of erythromycin side chain synthesis is dedicated
Reaction kettle.
Background technique
Erythromycin is a kind of alkaline antibiotic as caused by streptococcus, category macrolides, erythromycin system bacteriostatic agent, but
Also has bactericidal effect to highly sensitive bacterium at high concentrations, mechanism of action is to can pass through bacterial cell membrane, is supplied close
Position and the 50S subunit of bacterial ribosome at invertibity in conjunction with, blocking transfer ribonucleic acid is bound on the position " P ", while also being blocked
Polypeptide chain is suppressed bacterio protein synthesis, to play antibacterial action from by position to the displacement of the position " P ".And erythromycin side
Chain is the side shoot on erythromycin parent carbochain or carbocyclic ring chain.
In the production of erythromycin side chain, raw material is launched in reaction kettle, needs to open reaction kettle during reaction
A part of reactant is taken out, the response situation of erythromycin side chain is detected, but opens reaction kettle, not only will affect the close of reaction kettle
Feng Xing, and open reaction kettle kettle cover and be also more troublesome.
Utility model content
(1) the technical issues of solving
In view of the deficiencies of the prior art, the utility model provides a kind of erythromycin side chain synthesis special reactor, solves
When detecting the response situation of erythromycin side chain, reaction kettle is opened, not only will affect the leakproofness of reaction kettle, but also is opened anti-
The problem of answering kettle kettle cover to be also more troublesome.
(2) technical solution
To achieve the above object, the utility model provides the following technical solutions: a kind of erythromycin side chain synthesis Special reverse is answered
Kettle, including autoclave body, the autoclave body top movable are connected with kettle cover, and annulus, the circle are fixedly connected on the inner wall of the autoclave body
The upper surface of ring is connected with rubber spacer, and disk, the upper table of the disk are fixedly connected at the top of the rubber spacer
Face is fixed to be inlaid with first bearing, and the inner surface of the first bearing is fixedly connected with agitating shaft, and the surface of the agitating shaft is solid
Surely it is connected with stirring rod, and stirring rod is located at the inside of autoclave body, the surface of the kettle cover is fixedly connected with electric machine support, the electricity
Servo motor is fixedly connected at the top of machine support, the surface fixation of the kettle cover is inlaid with second bearing, the second bearing
Inner surface be fixedly connected with drive rod, and be fixedly connected at the top of the output shaft of servo motor and drive rod, the drive rod
Bottom be fixedly connected with hexagonal inserted link, and hexagonal inserted link is movably connected in the hexagonal jack opened up at the top of agitating shaft.
The upper surface fixation of the annulus is inlaid with feeding device, and the upper surface of the disk offers the first circular hole, institute
The surface for stating kettle cover offers the second circular hole, and feeding device extends through the first circular hole and the second circular hole and extends to kettle cover
Outside, is fixedly connected with cylinder on the inner wall of the kettle cover, and the internal activity of the cylinder is connected with motion bar, and motion bar
Bottom is flexibly connected with the upper surface of disk, and spring, and the other end and circle of spring are fixedly connected at the top of the motion bar
It is fixedly connected at the top of cylinder inner wall.
The feeding device includes feeding cylinder, and the surface of the feeding cylinder offers inlet port and outlet port respectively, and into
Material mouth is located at the lower section of annulus, and discharge port is located at the top of kettle cover, has been movably connected with first on the inner wall of the feeding cylinder
Piston and second piston, the equal fixing sleeve of the inner wall of the first piston and second piston is connected to connecting rod, and connecting rod is through simultaneously
The outside of feeding cylinder is extended to, the first piston is located at the lower section of feed inlet, and the second piston is located at feed inlet and discharging
Between mouthful.
Preferably, the bottom of the autoclave body is fixedly connected with supporting leg.
Preferably, the bottom fixation of the autoclave body is inlaid with discharge nozzle, and the surface of discharge nozzle is threaded with sealing cover.
Preferably, the inside radius of the annulus is 1 point 1 times of stirring rod and agitating shaft maximum horizontal range.
Preferably, push-and-pull block is fixedly connected at the top of the connecting rod.
Preferably, the first bearing uses mechanical seal.
(3) beneficial effect
The utility model provides a kind of erythromycin side chain synthesis special reactor, have it is following the utility model has the advantages that
The utility model is by setting disk, hexagonal inserted link and feeding device, when in use, opens kettle cover and takes disk
Autoclave body out, then erythromycin side chain synthesis material is added in autoclave body, then the first circular hole alignment feeding cylinder on disk will be justified
Disk is put into autoclave body, finally by the second circular hole alignment feeding cylinder by kettle cover cover simultaneously hexagonal inserted link be inserted into agitating shaft on hexagonal
In jack, servo motor work drives agitating shaft and stirring rod rotation to be stirred raw material, is needing to detect the original in autoclave body
Material reaction holds push-and-pull block at this time and moves upwards, drive first piston and the since raw material enters in feeding cylinder from feed inlet
Two piston upwards reuse syringe and are inserted into from discharge port by raw material to drive the raw material on first piston to move upwards
Absorption comes out, and detects to raw material, and analyzing the extent of reaction without opening kettle cover more will not cause dirt to the intracorporal raw material of kettle
Dye solves when detecting the response situation of erythromycin side chain, opens reaction kettle, not only will affect the leakproofness of reaction kettle, and
And open the problem of reaction kettle kettle cover is also more troublesome.
Detailed description of the invention
Fig. 1 is the utility model front elevational view；
Fig. 2 is the front elevational view of the utility model feeding device；
Fig. 3 is the front elevational view of the utility model cylinder.
In figure: 1 autoclave body, 2 kettle covers, 3 annulus, 4 rubber spacers, 5 disks, 6 first bearings, 7 agitating shafts, 8 stirring rods, 9 electricity
Machine support, 10 servo motors, 11 second bearings, 12 drive rods, 13 hexagonal inserted links, 14 feeding devices, 1401 feeding cylinders, 1402 into
Material mouth, 1403 discharge ports, 1404 first pistons, 1405 second pistons, 1406 connecting rods, 1407 push-and-pull blocks, 15 first circular holes, 16
Second circular hole, 17 cylinders, 18 motion bars, 19 springs, 20 supporting legs, 21 discharge nozzles.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
As shown in Figure 1-3, the utility model provides a kind of technical solution: a kind of erythromycin side chain synthesis special reactor,
Including autoclave body 1, the bottom of autoclave body 1 is fixedly connected with supporting leg 20, and the bottom of autoclave body 1 is fixed to be inlaid with discharge nozzle 21, and discharges
The surface of pipe 21 is threaded with sealing cover 22, after the reaction was completed, opens sealing cover from discharge nozzle 21 and releases reaction product, kettle
1 top movable of body is connected with kettle cover 2, and annulus 3 is fixedly connected on the inner wall of autoclave body 1, and the upper surface of annulus 3 is connected with rubber
Rubber mat layer 4, the top of rubber spacer 4 are fixedly connected with disk 5, and the upper surface of disk 5, which is fixed, is inlaid with first bearing 6, and first
Bearing 6 uses mechanical seal, and the inner surface of first bearing 6 is fixedly connected with agitating shaft 7, and the surface of agitating shaft 7 is fixedly connected with
Stirring rod 8, and stirring rod 8 is located at the inside of autoclave body 1, the inside radius of annulus 3 is 7 maximum horizontal range of stirring rod 8 and agitating shaft
1 point 1 times, allow stirring rod 7 by annulus 3 enter autoclave body 1 inside, the surface of kettle cover 2 is fixedly connected with motor
Bracket 9, the top of electric machine support 9 are fixedly connected with servo motor 10, and the power supply mode of servo motor 10 is external power supply, kettle cover
2 surface fixation is inlaid with second bearing 11, and the inner surface of second bearing 11 is fixedly connected with drive rod 12, and servo motor 10
Output shaft be fixedly connected with the top of drive rod 12, the bottom of drive rod 12 is fixedly connected with hexagonal inserted link 13, and hexagonal is inserted
Bar 13 is movably connected in the hexagonal jack opened up at the top of agitating shaft 7, can be effectively driven using hexagonal inserted link 13, and can
To dismantle kettle cover 2 and agitating shaft 7,7 heavier-weight of kettle cover 2 and agitating shaft is prevented, is made troubles to fractionation.
The upper surface fixation of annulus 3 is inlaid with feeding device 14, and the upper surface of disk 5 offers the first circular hole 15, kettle cover 2
Surface offer the second circular hole 16, and feeding device 14 extends through the first circular hole 15 and the second circular hole 16 and extends to kettle cover
2 outside is fixedly connected with cylinder 17 on the inner wall of kettle cover 2, and the internal activity of cylinder 17 is connected with motion bar 18, and motion bar
18 bottom is flexibly connected with the upper surface of disk 5, and the top of motion bar 18 is fixedly connected with spring 19, and spring 19 is another
It holds and is fixedly connected at the top of 17 inner wall of cylinder.
Feeding device 14 includes feeding cylinder 1401, and the surface of feeding cylinder 1401 offers feed inlet 1402 and discharge port respectively
1403, and feed inlet 1402 is located at the lower section of annulus 3, discharge port 1403 is located at the top of kettle cover 2, on the inner wall of feeding cylinder 1401
First piston 1404 and second piston 1405 have been movably connected with it, the inner wall of first piston 1404 and second piston 1405 is solid
Surely it is socketed with connecting rod 1406, and connecting rod 1406 runs through and extend to the outside of feeding cylinder 1401, first piston 1404 is located at
The lower section of feed inlet 1402, second piston 1405 is between feed inlet 1402 and discharge port 1403, the top of connecting rod 1406
It is fixedly connected with push-and-pull block 1407, since raw material enters in feeding cylinder 1401 from feed inlet 1402, holds push-and-pull block at this time
1407 move upwards, and first piston 1404 and second piston 1405 is driven to move upwards to drive the original on first piston 1404
Material moves upwards, and reuses syringe and is inserted into from discharge port 1403 and draw out by raw material, detects to raw material, analysis reaction
Degree.
Working principle: opening kettle cover 2 and disk 5 is taken out autoclave body 1, then autoclave body 1 is added in erythromycin side chain synthesis material
In, then the first circular hole 15 alignment feeding cylinder 1401 on disk 5 is put disk 5 in autoclave body 1 into, finally by the second circular hole 16
Alignment feeding cylinder 1401 covers kettle cover 2 while hexagonal inserted link 13 is inserted into the hexagonal jack on agitating shaft 7, and due to kettle cover 2
With the heavier-weight of servo motor 10, during kettle cover 2 moves downward, motion bar 18 is contacted with the upper surface of disk 5, with
Kettle cover 2 move downward, spring 19 is constantly compressed, spring 19 to motion bar 18 apply a downward power so that disk 5 squeeze
Rubber spacer 4 is pressed, the gap of annulus 3 and 5 junction of disk is eliminated, increases the leakproofness of device, 10 work belt of servo motor
Dynamic agitating shaft 7 and the rotation of stirring rod 8 are stirred raw material, are needing to detect the raw material reaction in autoclave body 1, due to raw material from into
Material mouth 1402 enters in feeding cylinder 1401, holds push-and-pull block 1407 at this time and moves upwards, drives first piston 1404 and second
Piston 1405 moves upwards that the raw material on first piston 1404 is driven to move upwards, and reuses syringe from discharge port 1403
Raw material is drawn out by insertion, detects to raw material, and the analysis extent of reaction more will not be in autoclave body 1 without opening kettle cover 2
Raw material pollute.
It can to sum up obtain, the utility model is by setting disk 5, hexagonal inserted link 13 and feeding device 14, when in use, solves
When detecting the response situation of erythromycin side chain, reaction kettle is opened, not only will affect the leakproofness of reaction kettle, but also is opened anti-
The problem of answering kettle kettle cover 2 to be also more troublesome.
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality
Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation
In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to
Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those
Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment
Intrinsic element.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (6)
1. a kind of erythromycin side chain synthesizes special reactor, including autoclave body (1), autoclave body (1) top movable are connected with kettle cover
(2), it is characterised in that: be fixedly connected with annulus (3) on the inner wall of the autoclave body (1), the upper surface activity of the annulus (3) connects
It is connected to rubber spacer (4), is fixedly connected with disk (5) at the top of the rubber spacer (4), the upper surface of the disk (5) is solid
Surely it is inlaid with first bearing (6), the inner surface of the first bearing (6) is fixedly connected with agitating shaft (7), the agitating shaft (7)
Surface be fixedly connected with stirring rod (8), and stirring rod (8) is located at the inside of autoclave body (1), and the surface of the kettle cover (2) is fixed
It is connected with electric machine support (9), is fixedly connected with servo motor (10) at the top of the electric machine support (9), the table of the kettle cover (2)
Face fixation is inlaid with second bearing (11), and the inner surface of the second bearing (11) is fixedly connected with drive rod (12), and servo
It is fixedly connected at the top of the output shaft of motor (10) and drive rod (12), the bottom of the drive rod (12) is fixedly connected with hexagonal
Inserted link (13), and hexagonal inserted link (13) is movably connected in the hexagonal jack opened up at the top of agitating shaft (7)；
The upper surface fixation of the annulus (3) is inlaid with feeding device (14), and the upper surface of the disk (5) offers the first circle
The surface in hole (15), the kettle cover (2) offers the second circular hole (16), and feeding device (14) extends through the first circular hole (15)
With the second circular hole (16) and the outsides of kettle cover (2) is extended to, is fixedly connected with cylinder (17), institute on the inner wall of the kettle cover (2)
The internal activity for stating cylinder (17) is connected with motion bar (18), and the activity of the upper surface of the bottom of motion bar (18) and disk (5)
It connects, is fixedly connected with spring (19) at the top of the motion bar (18), and the other end of spring (19) and cylinder (17) inner wall
Top be fixedly connected；
The feeding device (14) includes feeding cylinder (1401), and the surface of the feeding cylinder (1401) offers feed inlet respectively
(1402) and discharge port (1403), and feed inlet (1402) is located at the lower section of annulus (3), and discharge port (1403) is located at kettle cover (2)
Top, be movably connected with first piston (1404) and second piston (1405) on the inner wall of the feeding cylinder (1401),
The equal fixing sleeve of inner wall of the first piston (1404) and second piston (1405) is connected to connecting rod (1406), and connecting rod
(1406) run through and extend to the outside of feeding cylinder (1401), the first piston (1404) is located under feed inlet (1402)
Side, the second piston (1405) are located between feed inlet (1402) and discharge port (1403).
2. a kind of erythromycin side chain according to claim 1 synthesizes special reactor, it is characterised in that: the autoclave body (1)
Bottom be fixedly connected with supporting leg (20).
3. a kind of erythromycin side chain according to claim 1 synthesizes special reactor, it is characterised in that: the autoclave body (1)
Bottom fixation be inlaid with discharge nozzle (21), and the surface of discharge nozzle (21) is threaded with sealing cover (22).
4. a kind of erythromycin side chain according to claim 1 synthesizes special reactor, it is characterised in that: the annulus (3)
Inside radius be 1 point 1 times of stirring rod (8) and agitating shaft (7) maximum horizontal range.
5. a kind of erythromycin side chain according to claim 1 synthesizes special reactor, it is characterised in that: the connecting rod
(1406) push-and-pull block (1407) is fixedly connected at the top of.
6. a kind of erythromycin side chain according to claim 1 synthesizes special reactor, it is characterised in that: the first bearing
(6) mechanical seal is used.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820624706.9U CN208373079U (en) | 2018-04-28 | 2018-04-28 | A kind of erythromycin side chain synthesis special reactor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820624706.9U CN208373079U (en) | 2018-04-28 | 2018-04-28 | A kind of erythromycin side chain synthesis special reactor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208373079U true CN208373079U (en) | 2019-01-15 |
Family
ID=64973144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820624706.9U Expired - Fee Related CN208373079U (en) | 2018-04-28 | 2018-04-28 | A kind of erythromycin side chain synthesis special reactor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208373079U (en) |
-
2018
- 2018-04-28 CN CN201820624706.9U patent/CN208373079U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190115 |
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| CF01 | Termination of patent right due to non-payment of annual fee |