CN208239341U - A kind of micro-fluidic chip electrochemical detection device - Google Patents
A kind of micro-fluidic chip electrochemical detection device Download PDFInfo
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- CN208239341U CN208239341U CN201820770641.9U CN201820770641U CN208239341U CN 208239341 U CN208239341 U CN 208239341U CN 201820770641 U CN201820770641 U CN 201820770641U CN 208239341 U CN208239341 U CN 208239341U
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- fluidic chip
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- electrode
- sensing chamber
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Abstract
The utility model discloses a kind of micro-fluidic chip electrochemical detection devices, including cap, shell and main body, on the left of cap with shell card and, cap right side and housing hinge, housing cavity is equipped with main body, main body includes micro-fluidic chip, Electrophoresis Lab, sensing chamber, high-field electrode, grounding electrode, auxiliary electrode, reference electrode, detecting electrode and capillary, micro-fluidic chip both ends apertured hole one and hole two, hole one connects Electrophoresis Lab, hole two connects sensing chamber, Electrophoresis Lab and detection locular wall are equipped with through-hole, the connection capillary of Electrophoresis Lab and sensing chamber, electrophoresis locular wall interts high-field electrode, it detects locular wall and interts auxiliary electrode, reference electrode, detecting electrode, Electrophoresis Lab and sensing chamber lower end are stuck in fixing groove, resilient cushion is set in fixing groove, micro-fluidic chip edge and inner walls card and, inner walls set fixing axle, fixing axle connects lever.The utility model is automatically performed detection overall process using micro-fluidic chip, needs sample size few, and accuracy in detection is high.
Description
Technical field
The utility model relates to a kind of electrochemical detection device field, specifically a kind of micro-fluidic chip Electrochemical Detection dress
It sets.
Background technique
Microfluidic chip technology is bases such as biology, chemistry, the sample preparation of medical analysis process, reaction, separation, detections
This operating unit is integrated on the chip of one piece of micro-meter scale, is automatically performed analysis overall process, since it is in biology, chemistry, doctor
The great potential in etc. fields has been developed as the friendship of the subjects such as biology, chemistry, medicine, fluid, electronics, material, a machinery
The brand-new research field of fork, wherein detection technique is one of core technology of micro-fluidic chip, such as field of electrochemical detection, is passed
The electrochemical detection method multiplicity of system, but need sample size big, detection sensitivity is low, poor reproducibility, therefore provides a kind of miniflow
Controlling chip electrochemical detection device becomes current urgent problem.
Summary of the invention
1, it to solve the problems, such as
For existing Conventional electrochemical detection method multiplicity, but need sample size big, detection sensitivity is low, poor reproducibility
Problem, it is automatic using micro-fluidic chip the purpose of this utility model is to provide a kind of micro-fluidic chip electrochemical detection device
Analysis overall process is completed, the sample size needed is few, and accuracy in detection is high, to solve the problems mentioned in the above background technology.
2, technical solution
To achieve the above object, the utility model provides the following technical solutions:
A kind of micro-fluidic chip electrochemical detection device, including cap, shell and main body, the cap left side edge protrusion
And with shell card and, on the right side of the cap and housing hinge, the housing cavity are equipped with main body, and the main body includes micro-fluidic core
Piece, Electrophoresis Lab, sensing chamber, high-field electrode, grounding electrode, auxiliary electrode, reference electrode, detecting electrode and capillary, it is described micro-
Fluidic chip both ends are respectively set hole one and hole two, and described hole one connects Electrophoresis Lab, two connecting detection room of described hole,
It is equipped with through-hole on the Electrophoresis Lab and detection locular wall, the micro-fluidic chip upper surface between the Electrophoresis Lab and sensing chamber is equipped with
Groove, the groove is interior to be equipped with capillary, two high-field electrodes is interted in the through-hole of the electrophoresis locular wall, the sensing chamber leads to
Intert auxiliary electrode, reference electrode, detecting electrode in hole, the detecting electrode right end passes through micro-fluidic chip and shell and external
Signal converter, the Electrophoresis Lab and sensing chamber lower end are stuck in fixing groove, and the fixing groove is located at housing bottom surface, the fixation
Be equipped in slot resilient cushion, the micro-fluidic chip edge and inner walls card and, the inner walls are described solid equipped with fixing axle
Dead axle connects lever.
As a further solution of the present invention: the cap is transparent material.
Described hole one and hole two are equipped with internal screw thread as a further solution of the present invention,.
The Electrophoresis Lab and sensing chamber upper end are equipped with external screw thread as a further solution of the present invention,.
Described hole one is threadedly coupled Electrophoresis Lab as a further solution of the present invention,.
Described hole two is threadedly coupled sensing chamber as a further solution of the present invention,.
As a further solution of the present invention, the capillary both ends pass through through-hole respectively with Electrophoresis Lab and detection
Room connection.
The through-hole of the interspersed detecting electrode is opposite with capillary outlet as a further solution of the present invention, sets
It sets.
As a further solution of the present invention, the resilient cushion with Electrophoresis Lab and sensing chamber are soft contacts.
The lever is rotated around fixing axle as a further solution of the present invention,.
3, beneficial effect
Compared with prior art, the utility model has the beneficial effects that
(1) the utility model is automatically performed analysis overall process using micro-fluidic chip, and the sample size needed is few, and detection is accurate
Degree is high.
(2) Electrophoresis Lab and sensing chamber are threadedly coupled on the micro-fluidic chip of the utility model, it is easy for installation, convenient for clear
It washes.
(3) the utility model separately carries out electrophoresis and detection, avoids interfering, and accuracy in detection is high.
(4) the utility model detecting electrode and capillary outlet are oppositely arranged the sensitivity and reproduction for improving detection device
Property.
(5) the utility model protects Electrophoresis Lab and sensing chamber by fixing groove, resilient cushion.
(6) the utility model protects micro-fluidic chip by fixing axle, lever.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of micro-fluidic chip electrochemical detection device.
Fig. 2 is the top view of micro-fluidic chip electrochemical detection device.
In figure: 1- cap；2- shell；3- main body；4- micro-fluidic chip；5- hole one；6- Electrophoresis Lab；7- high-field electrode；
8- fixing groove；9- resilient cushion；10- hole two；11- sensing chamber；12- detecting electrode；13- capillary；14- fixing axle；15- grades
Bar；16- reference electrode；17- grounding electrode；18- auxiliary electrode.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Please refer to Fig. 1~2, in the utility model embodiment, a kind of micro-fluidic chip electrochemical detection device, including cap
1, shell 2 and main body 3, the cap 1 are transparent material, observation when convenient for detection, 1 left side edge of cap protrusion and with
The card of shell 2 and, 1 right side of the cap and shell 2 are hinged, and 2 inner cavity of shell is equipped with main body 3, and the main body 3 includes miniflow
Control chip 4, Electrophoresis Lab 6, sensing chamber 11, high-field electrode 7, grounding electrode 17, auxiliary electrode 18, reference electrode 16, detecting electrode
12 and capillary 13,4 both ends of micro-fluidic chip hole 1 and hole 2 10, described hole 1 and hole is respectively set
2 10 are equipped with internal screw thread, and the Electrophoresis Lab 6 and 11 upper end of sensing chamber are equipped with external screw thread, and described hole 1 is threadedly coupled electricity
Swimming room 6, described hole 2 10 is threadedly coupled sensing chamber 11, is equipped with through-hole on 11 wall of the Electrophoresis Lab 6 and sensing chamber, described
4 upper surface of micro-fluidic chip between Electrophoresis Lab 6 and sensing chamber 11 is equipped with groove, and capillary 13 is equipped in the groove, described
13 both ends of capillary pass through through-hole and connect respectively with Electrophoresis Lab 6 and sensing chamber 11, and two are interted in the through-hole of 6 wall of Electrophoresis Lab
High-field electrode 7 interts auxiliary electrode 18, reference electrode 16, detecting electrode 12, the interspersed inspection in the through-hole of the sensing chamber 11
The through-hole and the outlet of capillary 13 for surveying electrode 12 are oppositely arranged, and 12 right end of detecting electrode passes through micro-fluidic chip 4 and shell
2 and outer signal converter, chemical signal is converted into electric signal, the Electrophoresis Lab 6 and 11 lower end of sensing chamber are stuck in fixing groove 8
Interior, the fixing groove 8 is located at 2 bottom surface of shell, is equipped with resilient cushion 9 in the fixing groove 8, the resilient cushion 9 and Electrophoresis Lab 6 and
The soft contact of sensing chamber 11, to be protected to Electrophoresis Lab 6 and sensing chamber 11,4 edge of micro-fluidic chip and 2 inner wall of shell
Card and, 2 inner wall of shell is equipped with fixing axle 14, and the fixing axle 14 connects lever 15, and the lever 15 can surround fixing axle
Micro-fluidic chip 4 can be firmly stuck in shell 2 by rotating lever 15, enhance the stability of main body 3 by 14 rotations.
The working principle of the utility model is: rotation lever 15 takes out micro-fluidic chip 4, the mode being connected through a screw thread will
Electrophoresis Lab 6 and sensing chamber 11 are respectively charged into the hole 1 and hole 2 10 at 4 both ends of micro-fluidic chip, on one 50 wall of hole
Through-hole in be inserted into high-field electrode 7, auxiliary electrode 18, reference electrode 16 are inserted into the through-hole on 2 10 wall of hole, by electrophoresis
Room 6 and sensing chamber 11 are put into fixing groove 8, and the fixed micro-fluidic chip 4 of rotation lever 15 is inserted into detecting electrode 12, makes itself and capillary
Pipe 13 exports relatively, then sample solution and buffer solution are added into Electrophoresis Lab 6, and buffer solution is added into sensing chamber 11, leads to
Sample ionizes under the effect of high-field electrode 7 and enters capillary 13 after electricity, and final sample enters sensing chamber 11 along capillary 13
And meet with detecting electrode 12, detection is completed under 12 collective effect of auxiliary electrode 18, reference electrode 16 and detecting electrode.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and
And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this is practical new in other specific forms
Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this is practical new
The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing for the equivalent requirements of the claims will be fallen in
All changes in justice and range are embraced therein.It should not treat any reference in the claims as limiting
Related claim.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiments being understood that.
Claims (10)
1. a kind of micro-fluidic chip electrochemical detection device, including cap (1), shell (2) and main body (3), which is characterized in that institute
State cap (1) left side edge protrusion and with shell (2) card and, on the right side of the cap (1) and shell (2) hingedly, the shell (2)
Inner cavity is equipped with main body (3), and the main body (3) includes micro-fluidic chip (4), Electrophoresis Lab (6), sensing chamber (11), high-field electrode
(7), grounding electrode (17), auxiliary electrode (18), reference electrode (16), detecting electrode (12) and capillary (13), the miniflow
Hole one (5) and hole two (10) is respectively set in control chip (4) both ends, and described hole one (5) connects Electrophoresis Lab (6), the hole
Through-hole, the Electrophoresis Lab (6) are equipped on hole two (10) connecting detection room (11), the Electrophoresis Lab (6) and sensing chamber (11) wall
Micro-fluidic chip (4) upper surface between sensing chamber (11) is equipped with groove, is equipped with capillary (13) in the groove, the electricity
Swim and intert two high-field electrodes (7) in the through-hole of room (6) wall, intert in the through-hole of the sensing chamber (11) auxiliary electrode (18),
Reference electrode (16), detecting electrode (12), detecting electrode (12) right end passes through micro-fluidic chip (4) and shell (2) is simultaneously outer
Signal converter is connect, the Electrophoresis Lab (6) and sensing chamber (11) lower end are stuck in fixing groove (8), and the fixing groove (8) is located at shell
Body (2) bottom surface, the fixing groove (8) is interior to be equipped with resilient cushion (9), micro-fluidic chip (4) edge and shell (2) inner wall card
Fixing axle (14) are equipped with, shell (2) inner wall, the fixing axle (14) connects lever (15).
2. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that the cap (1) is
Bright material.
3. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that described hole one (5) and
Hole two (10) is equipped with internal screw thread.
4. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that the Electrophoresis Lab (6) and
Sensing chamber (11) upper end is equipped with external screw thread.
5. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that described hole one (5) spiral shell
Line connects Electrophoresis Lab (6).
6. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that described hole two (10) spiral shell
Line connecting detection room (11).
7. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that the capillary (13)
Both ends pass through through-hole and connect respectively with Electrophoresis Lab (6) and sensing chamber (11).
8. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that the interspersed detecting electrode
(12) through-hole is oppositely arranged with capillary (13) outlet.
9. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that the resilient cushion (9) with
Electrophoresis Lab (6) and sensing chamber (11) soft contact.
10. micro-fluidic chip electrochemical detection device according to claim 1, which is characterized in that the lever (15) is enclosed
It is rotated around fixing axle (14).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820770641.9U CN208239341U (en) | 2018-05-23 | 2018-05-23 | A kind of micro-fluidic chip electrochemical detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820770641.9U CN208239341U (en) | 2018-05-23 | 2018-05-23 | A kind of micro-fluidic chip electrochemical detection device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208239341U true CN208239341U (en) | 2018-12-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820770641.9U Expired - Fee Related CN208239341U (en) | 2018-05-23 | 2018-05-23 | A kind of micro-fluidic chip electrochemical detection device |
Country Status (1)
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| CN (1) | CN208239341U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112080806A (en) * | 2020-10-23 | 2020-12-15 | 江苏吉诺思美精准医学科技有限公司 | Plasma free DNA (deoxyribonucleic acid) library building method of capillary 96-pore plate |
-
2018
- 2018-05-23 CN CN201820770641.9U patent/CN208239341U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112080806A (en) * | 2020-10-23 | 2020-12-15 | 江苏吉诺思美精准医学科技有限公司 | Plasma free DNA (deoxyribonucleic acid) library building method of capillary 96-pore plate |
| CN112080806B (en) * | 2020-10-23 | 2024-02-20 | 江苏吉诺思美精准医学科技有限公司 | Plasma free DNA library construction method of capillary 96-well plate |
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|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181214 Termination date: 20190523 |
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| CF01 | Termination of patent right due to non-payment of annual fee |