CN208171874U - A kind of holographic imaging cell detection device focused based on simple lens - Google Patents
A kind of holographic imaging cell detection device focused based on simple lens Download PDFInfo
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- CN208171874U CN208171874U CN201820813099.0U CN201820813099U CN208171874U CN 208171874 U CN208171874 U CN 208171874U CN 201820813099 U CN201820813099 U CN 201820813099U CN 208171874 U CN208171874 U CN 208171874U
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- lifting tube
- fixed cylinder
- measured
- gear
- cell sample
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Abstract
The utility model provides a kind of holographic imaging cell detection device focused based on simple lens, including lifting tube, fixed cylinder, rack gear, gear, lower box, upper box, bracket, cell sample smear fixing seat to be measured, ccd sensor image-taking device and convex lens, the junction of lower box and upper box is equipped with cell sample smear fixing seat to be measured, ccd sensor image-taking device is installed on lower box, fixed cylinder is installed on upper box, the outside of fixed cylinder is equipped with the gear on bracket and bracket, lifting tube is set in fixed cylinder, convex lens and bolt are installed on lifting tube, the rack gear being meshed with gear is installed on the outside of lifting tube, ccd sensor image-taking device, convex lens and the center Jun Chu of cell sample smear fixing seat to be measured are on the same axis.Unsharp limitation that part when the utility model overcomes tradition without lens holographic imaging cell capture generates due to by luminosity difference, realizes to the quick and accurate capture in the part of cell sample smear.
Description
Technical field
The utility model belongs to no lens holographic imaging technical field of image processing, is specifically related to a kind of based on simple lens
The holographic imaging cell detection device of focusing.
Background technique
Computer image processing technology be it is a kind of by picture signal be converted into digital signal and using computer programming to it
The technology handled.Since the processing speed of computer is exceedingly fast, and digital signal has small, easy to maintain, the easy transmission of distortion, resists
The features such as interference performance is strong, thus computer image processing technology using very extensive, arrive scientific research, defense military greatly, as low as
The every aspect of people's production and living.For example, in health care, communication, communications and transportation, office automation, geophysics, atmosphere
Environment, satellite remote sensing and the application of industrial automation are just more and more.
Traditional cell detection requires observer to have higher operation requirement to the such high precision instrument of microscope, and to cell
The extraction workload of sample digital picture is very big, time- and labor-consuming, and there is also the limitations in space and environmental condition in operation.This
Outside, traditional cell detection is inevitably present the subjective factor of people, so as to cause different testing staff to same cell sample
This digital picture has different extractions as a result, eventually leading to that extract result fluctuation larger.
By years development, optical microscopy has become a kind of indispensable detection instrument in many scientific domains, especially
It is field of biological detection.But it also just like relatively cumbersome, low efficiency and operates the apparent disadvantage such as complicated, is showing such as
The present requires higher and higher and operating environment to become increasingly complex the unknown cell detection speed and precision brought at any time
Under background, it is badly in need of a kind of simple and light while local cells can be clearly observed, detects speed and precision and all reach and want
The novel microscope asked as conventional microscope substitute.
Utility model content
For the above-mentioned prior art, the technical problem to be solved by the present invention is to provide one kind to be focused based on simple lens
Holographic imaging cell detection device, the device be used for detect cell to be measured and make obtain image local clearly become clear, so as to
Efficiently and effectively understand individual cells shape, further research is made to the local message of cell to be measured.
In order to solve the above technical problems, the utility model provides a kind of holographic imaging cell inspection focused based on simple lens
Survey device, including lifting tube, fixed cylinder, rack gear, gear, bracket, lower box, upper box, cell sample smear fixing seat to be measured
With ccd sensor image-taking device, the upper box is fixedly connected with right above the lower box, in the lower box and top box
The junction of body is equipped with the cell sample smear fixing seat to be measured, and the middle position of the lower box bottom is equipped with described
Ccd sensor image-taking device, the middle position at the top of the upper box is equipped with the fixed cylinder communicated with upper box, in institute
It states the top surface of upper box, be provided with the bracket on the outside of fixed cylinder, the top of the bracket is equipped with the gear, described
It is set with the lifting tube in fixed cylinder, the rack gear being meshed with the gear is installed on the outside of the lifting tube, it is described
Middle position at the top of lifting tube is equipped with convex lens, the ccd sensor image-taking device, convex lens and cell sample to be measured
On the same axis, on the lifting tube side of the relatively described bracket is equipped with the center Jun Chu of smear fixing seat can fix liter
The bolt of cylinder drops.
More preferably, the focal length of the convex lens is 10cm ~ 20cm.
Compared with the prior art, the utility model has the beneficial effects that：
1, the utility model does not need completely coherent light source (such as laser) compared with no lens holographic imaging, and only needs
Simple fluorescent lamp, light emitting diode etc.（Incoherent light source）Substitute laser（Coherent source）As light source.
2, for the utility model by using convex lens, the illumination that may make local cells to be subject in this way is more, the brightness of presentation
Greatly, good resolution, while the influence of the illumination of insufficient pair of local cells of illumination is reduced, to simplify in later image processing
The cause processing insufficient to the brightness of individual cells or a small number of range inner cells and illumination.
3, the utility model takes digital picture by using optical sensor CCD, in this way can be to Oral Mucosal Cells, the frog
The animal and plant macromolecular cell such as egg cell, onion epidermis cell, blade cell carries out high-resolution volume and takes, then through counting
Calculation machine driver captures image.
4, the utility model also has the characteristics that easy to carry, assembling is simple, easy to operate, processing is quick.
Detailed description of the invention
Fig. 1 is a kind of main view of the holographic imaging cell detection device focused based on simple lens of the utility model.
Fig. 2 is the sectional view of Fig. 1.
Fig. 3 is the cross-sectional view of B-B in Fig. 2.
Fig. 4 is the sectional view of A-A in Fig. 2.
Fig. 5 is traditional light path principle figure without lens holographic imaging.
Fig. 6 is the light path principle figure that the utility model is focused based on simple lens.
It illustrates：1- lifting tube, 2- fixed cylinder, 3- rack gear, 4- gear, 5- bracket, 6- lower box, 7- upper box, 8-
Bolt, 9- upper and lower box fixing bolt, 10- cell sample smear fixing seat to be measured, 11-CCD sensor image-taking device, 12- are convex
Lens, 13- baffle of porous baffle, X- object under test sample smear.
Specific embodiment
The utility model is further described with preferred embodiment with reference to the accompanying drawing.
It is as shown in Figures 1 to 4 a kind of holographic imaging cell detection device focused based on simple lens of the utility model
Structural schematic diagram, including lifting tube 1, fixed cylinder 2, rack gear 3, gear 4, bracket 5, lower box 6, upper box 7, bolt 8, upper nowel
Body fixing bolt 9, cell sample smear fixing seat 10 to be measured, ccd sensor image-taking device 11, convex lens 12, baffle of porous baffle 13
With cell sample smear X to be measured.
Upper box 7 is fixedly connected with by upper and lower box fixing bolt 9 in the surface of above-mentioned lower box 6, in lower box 6
Cell sample smear fixing seat 10 to be measured is installed with the junction of upper box 7, and in cell sample smear fixing seat 10 to be measured
On be placed with cell sample smear X to be measured.Ccd sensor image-taking device 11 is installed in the middle position of 6 bottom of lower box,
The middle position at 7 top of upper box is equipped with the fixed cylinder 2 communicated with upper box 7.The top surface of upper box 7, fixed cylinder 2 it is outer
Side is equipped with bracket 5, and is equipped with gear 4 on the top of bracket 5.It is set with lifting tube 1 in fixed cylinder 2, is pushed up in lifting tube 1
The middle position in portion is equipped with convex lens 12, and the focal length of the convex lens is 10cm ~ 20cm.The outside of lifting tube 1 be equipped with
The rack gear 3 that said gear 4 is meshed, the side on lifting tube 1 with respect to bracket 5 are equipped with the bolt 8 that can fix lifting tube 1.
The center of above-mentioned ccd sensor image-taking device 11, convex lens 12 and cell sample smear fixing seat 10 to be measured is in same
On axis.
Utility model device passes through 3D printer printing and making.
When the utility model operates, cell sample smear X to be measured is placed in cell sample smear fixing seat to be measured first
On 10, beam orthogonal made of the light planoconvex lens 12 right above lifting tube 1 and fixed cylinder 2 converge is irradiated in cell sample to be measured
On smear X.Light beam after convergence exposes on ccd sensor image-taking device 11 through cell sample smear X to be measured, CCD sensing
Device image-taking device 11 is sent to computer by the image data that USB interface data line will acquire.Meanwhile the light beam after convergence
The lifting that lifting tube 1 is reconciled through gear 4 is in this way imaged the cell smear being placed in cell sample smear fixing seat 10 to be measured
It is clear to reach part.Computer is driven using software VLC media player, and the image of said extracted is stored in.
As shown in figure 5, that light source selection of the tradition without lens holographic light path is partially coherent light D, partially coherent light D passes through
Baffle of porous baffle 13 is radiated on cell sample smear X to be measured, and partially coherent light D throws imaging through cell sample smear X to be measured
It penetrates on ccd sensor sampling image lens 11.For the not acutance for reducing image, baffle of porous baffle 13 and cell sample smear X's to be measured
Distance Z1 is far longer than cell sample smear X to be measured and 11 distance Z2 of ccd sensor sampling image lens.Tradition is without lens holographic optical
Influence of the road image because of light source uniform irradiation on entire cell smear sample to be measured, will cause in ccd sensor sampling image lens
The received illumination through cell sample smear X to be measured is few on 11, to keep whole imaging brightness not strong enough, resolution ratio is inadequate
Height, cell edges are fuzzy, are unfavorable for the processing of later period cell image.
As shown in fig. 6, that light source selection of the utility model without lens holographic light path is incoherent light D, incoherent light D is logical
The convex lens 12 crossed on baffle of porous baffle 13 converges in light on cell sample smear X to be measured, and incoherent light D penetrates cell to be measured
Imaging is projeced on ccd sensor sampling image lens 11 by sample smear X.Baffle of porous baffle 13 and cell sample smear X to be measured away from
From Z1 and cell sample smear X to be measured and 11 distance Z2 of ccd sensor sampling image lens with traditional no lens holographic light path
It is identical.Cell imaging of the utility model without lens holographic light path can make the resolving power enhancing of imaging because of the effect of convergence light source,
The brightness of local cells increases, and cell edges are high-visible, and nucleus can also observe with the naked eye, after greatly facilitating in this way
Processing of the phase to cell image.
The above only expresses preferred embodiments of the present invention, and the description thereof is more specific and detailed, but not
Therefore it can be interpreted as that a limitation on the scope of the patent of the present invention.It should be pointed out that for the ordinary skill people of this field
For member, without departing from the concept of the premise utility, several deformations can also be made, improves and substitutes, these all belong to
In the protection scope of the utility model.Therefore, the scope of protection shall be subject to the appended claims for the utility model patent.
Claims (2)
1. a kind of holographic imaging cell detection device focused based on simple lens, including lifting tube（1）, fixed cylinder（2）, rack gear
（3）, gear（4）, bracket（5）, lower box（6）, upper box（7）, cell sample smear fixing seat to be measured（10）And ccd sensor
Image-taking device（11）, the lower box（6）Surface be fixedly connected with the upper box（7）, in the lower box（6）With it is upper
Cabinet（7）Junction the cell sample smear fixing seat to be measured is installed（10）, the lower box（6）The interposition of bottom
It sets and the ccd sensor image-taking device is installed（11）, the upper box（7）The middle position at top is equipped with and upper box
（7）The fixed cylinder communicated（2）, in the upper box（7）Top surface, fixed cylinder（2）Outside be provided with the bracket
（5）, the bracket（5）Top the gear is installed（4）, in the fixed cylinder（2）On be set with the lifting tube（1）,
In the lifting tube（1）Outside be equipped with and the gear（4）The rack gear being meshed（3）, it is characterised in that：The lifting tube
（1）The middle position at top is equipped with convex lens（12）, the ccd sensor image-taking device（11）, convex lens（12）And to
Survey cell sample smear fixing seat（10）Center Jun Chu on the same axis, the lifting tube（1）On the relatively described bracket（5）
Side the bolt that can fix lifting tube is installed（8）.
2. a kind of holographic imaging cell detection device focused based on simple lens according to claim 1, it is characterised in that：
The convex lens（12）Focal length be 10cm ~ 20cm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820813099.0U CN208171874U (en) | 2018-05-29 | 2018-05-29 | A kind of holographic imaging cell detection device focused based on simple lens |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820813099.0U CN208171874U (en) | 2018-05-29 | 2018-05-29 | A kind of holographic imaging cell detection device focused based on simple lens |
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| Publication Number | Publication Date |
|---|---|
| CN208171874U true CN208171874U (en) | 2018-11-30 |
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|---|---|---|---|
| CN201820813099.0U Expired - Fee Related CN208171874U (en) | 2018-05-29 | 2018-05-29 | A kind of holographic imaging cell detection device focused based on simple lens |
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| CN (1) | CN208171874U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109828423A (en) * | 2019-02-28 | 2019-05-31 | 西安理工大学 | Light-source system applied to no lens imaging device |
| CN110231276A (en) * | 2019-05-28 | 2019-09-13 | 西安理工大学 | Cell size measuring device and its measurement method without lens imaging system |
-
2018
- 2018-05-29 CN CN201820813099.0U patent/CN208171874U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109828423A (en) * | 2019-02-28 | 2019-05-31 | 西安理工大学 | Light-source system applied to no lens imaging device |
| CN110231276A (en) * | 2019-05-28 | 2019-09-13 | 西安理工大学 | Cell size measuring device and its measurement method without lens imaging system |
| CN110231276B (en) * | 2019-05-28 | 2022-01-07 | 西安理工大学 | Cell size measuring device of lens-free imaging system and measuring method thereof |
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181130 Termination date: 20190529 |