CN208131050U - The micro-fluidic disc of various concentration sample detection - Google Patents
The micro-fluidic disc of various concentration sample detection Download PDFInfo
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- CN208131050U CN208131050U CN201820107551.1U CN201820107551U CN208131050U CN 208131050 U CN208131050 U CN 208131050U CN 201820107551 U CN201820107551 U CN 201820107551U CN 208131050 U CN208131050 U CN 208131050U
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- microchannel
- disc
- detection
- micro
- various concentration
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Abstract
The utility model discloses the micro-fluidic discs of various concentration sample detection, including disc, microchannel, microchannel sample inlets, microchannel buffer inlet, reaction and detection mouth.Microchannel, microchannel entrance and detection mouth are carved on the disc；Microchannel entrance is positioned at disc inside edge around the half tubular and half tubular 8 entrances below, entrance are connect with detection mouth by microchannel of the center of circle.The device is made determinand rapid dilution and is reacted in the way of rotating centrifugal, is conducive to find suitable detection mouth, is shortened detection time；8 groups of microchannels are provided with, the dilution and detection of 4 road various concentration samples of 8 groups of differential responses can be carried out with the time, greatly reduces cost, improve detection efficiency and reduce its dependence to operating outside chip.
Description
Technical field
The utility model relates to the micro-fluidic discs that micro-fluidic field more particularly to a kind of various concentration sample are detected.
Background technique
Microfluidic chip technology is bases such as biology, chemistry, the sample preparation of medical analysis process, reaction, separation, detections
This operating unit is integrated on the chip of one piece of micro-meter scale, is automatically performed analysis overall process.Its advantage is that：Amount of samples is few,
It is fast to analyze speed, convenient for portable instrument is made, is highly suitable for even if, field assay.It has been developed as a biology, change
The brand-new research field of the subject crossings such as, medicine, fluid, electronics, material, machinery.
In current micro-fluidic field, micro-fluidic chip is directed to single reagent reaction mostly, detects various concentration
When, it needs artificially to configure dilution reagent.For needing repeated multiple times diluted test, there are large errors for artificial configuration dilution.
Such as the utility model patent of number of patent application 201621344254.6, attracted each other with magnet and rotating centrifugal using magnetic
Mode realizes multi-way detecting, but the disadvantage is that：Detection object is single and needs artificial configuration diluent liquid, and exists artificial
Large error is caused when dilution, the dependence that configuration process externally operates is larger；For another example number of patent application 201610268972.8
Patent of invention, in the way of electrochemistry and centrifugation by the link of the pre-treatment to sample realize extraction to sample,
Reaction, filtering, the integration detected, disadvantage are also to rely on the manual operation outside chip in configuration.
Summary of the invention
For the above-mentioned problems in the prior art, the purpose of this utility model is to provide a kind of various concentration samples
The micro-fluidic disc of detection is conducive to seek its object is to make determinand rapid dilution in the way of rotating centrifugal and react
It looks for suitable detection mouth, shortens detection time and its less dependence to operating outside chip, make accurate data；It is provided with more
Road microchannel, the multichannel that differential responses can be carried out with the time dilute detection, greatly reduce cost, improve detection efficiency.
Technical solution that the utility model uses for：The micro-fluidic disc of various concentration sample detection, including disc（1）,
Microchannel（2）, microchannel sample inlets（3）, microchannel buffer inlet（4）, reaction and detection mouth（5）；The disc（1）
On be carved with microchannel（2）, 8 microchannel sample inlets（3）, microchannel buffer inlet（4）, reaction and detection mouth（5）；It is micro- logical
Road buffer inlet（4）For positioned at disc（1）Inside edge around the half tubular of the center of circle；Microchannel sample inlets（3）For semicanal
8 following entrances of shape, microchannel sample inlets（3）, microchannel buffer inlet（4）With react and detection mouth（5）By micro-
Channel（2）Connection.
The microchannel（2）Diameter be 1 μm ~ 200 μm.
The microchannel（2）, microchannel sample inlets（3）With reaction and detection mouth（5）Angularly divide along disc diameter
Cloth.
The microchannel buffer inlet（4）With at a distance from disc inside edge be 1~2cm.
The microchannel（2）It is mixed step by step for 8 " ten " word of Unit four channels.
The beneficial effects of the utility model are：
1. being provided with 8 groups of microchannels, the dilution and inspection of 4 road various concentration samples of 8 groups of differential responses can be carried out with the time
It surveys, greatly reduces cost, improve detection efficiency and reduce its dependence to operating outside chip, make accurate data;
2. making determinand rapid dilution in the way of rotating centrifugal and reacting, be conducive to find suitable detection mouth, contract
Short detection time.
Detailed description of the invention
With reference to the accompanying drawing and concrete mode the utility model is described in further detail.
Fig. 1 is the Facad structure figure of the utility model；
Fig. 2 is the schematic enlarged-scale view of disc；
In figure, 1 it is disc, 2 is microchannel, 3 is microchannel sample inlets, 4 is microchannel buffer inlet, 5 is reaction
And detection mouth.
Specific embodiment
In Fig. 1, Fig. 2, the micro-fluidic disc of various concentration sample detection, including disc 1, microchannel 2, microchannel sample enter
Mouth 3, microchannel buffer inlet 4, reaction and detection mouth 5；Microchannel 2 that diameter is 1 μm ~ 200 μm, micro- logical is carved on disc 1
Road sample inlets 3, microchannel buffer inlet 4, reaction and detection mouth 5；Microchannel sample inlets 3, reaction and detection mouth 5 are spacious
Shape cylindrical groove；Microchannel buffer inlet 4 is located at the inside of disc 1, and one around the center of circle encloses half tubular slot, away from interior survey edge
Distance is 1 ~ 2cm；Microchannel sample inlets 3 are located at 8 entrances that half tubular slot periphery is angularly distributed；Reaction and detection mouth 5
Positioned at the outer ledge of disc 1.Microchannel sample inlets 3 and microchannel buffer inlet 4 pass through micro- logical in reaction and detection mouth 5
Road 2 connects.Microchannel 2, microchannel sample inlets 3 and reaction and detection mouth 5 are angularly distributed along disc diameter.
The micro-fluidic disc course of work of various concentration sample detection：In microchannel, buffer is added in buffer inlet 4（Such as
Water）, appropriate sample is added in microchannel sample inlets 3, detection solution is added in reaction and detection mouth 5（As fluorescence tries
Agent）, disc 1 is fixed on Rotation Controllers and carries out rotating centrifugal, buffer and sample mixed by " ten " word microchannel 2 by
Grade dilution, and reacted detecting and reacting in mouth 5, finally detect.Totally 8 groups of microchannels can carry out 8 groups of differential responses with the time
The dilution and detection of 4 road various concentration samples.
Claims (3)
1. the micro-fluidic disc of various concentration sample detection, including disc（1）, microchannel（2）, microchannel sample inlets（3）, it is micro-
Channel buffers entrance（4）, reaction and detection mouth（5）；The disc（1）On be carved with microchannel（2）, 8 microchannel samples
Entrance（3）, microchannel buffer inlet（4）, reaction and detection mouth（5）；Microchannel sample inlets（3）, microchannel buffer enters
Mouthful（4）With react and detection mouth（5）Pass through microchannel（2）Connection；The microchannel buffer inlet（4）For positioned at disc
（1）Inside edge around the half tubular of the center of circle；It is characterized in that：The microchannel sample inlets（3）For half tubular 8 below
A entrance, the microchannel（2）For 8 " ten " word of Unit four channels, the microchannel（2）, microchannel sample inlets（3）
With reaction and detection mouth（5）It is angularly distributed along disc diameter.
2. the micro-fluidic disc of various concentration sample detection according to claim 1, which is characterized in that described is micro- logical
Road（2）Diameter be 1 μm ~ 200 μm.
3. the micro-fluidic disc of various concentration sample detection according to claim 1, which is characterized in that described is micro- logical
Road buffer inlet（4）With at a distance from disc inside edge be 1 ~ 2cm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820107551.1U CN208131050U (en) | 2018-01-23 | 2018-01-23 | The micro-fluidic disc of various concentration sample detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820107551.1U CN208131050U (en) | 2018-01-23 | 2018-01-23 | The micro-fluidic disc of various concentration sample detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208131050U true CN208131050U (en) | 2018-11-23 |
Family
ID=64285212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820107551.1U Expired - Fee Related CN208131050U (en) | 2018-01-23 | 2018-01-23 | The micro-fluidic disc of various concentration sample detection |
Country Status (1)
| Country | Link |
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| CN (1) | CN208131050U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112076806A (en) * | 2019-06-14 | 2020-12-15 | 中国科学院青岛生物能源与过程研究所 | Centrifugal enrichment microfluidic chip for low-concentration liquid sample |
-
2018
- 2018-01-23 CN CN201820107551.1U patent/CN208131050U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112076806A (en) * | 2019-06-14 | 2020-12-15 | 中国科学院青岛生物能源与过程研究所 | Centrifugal enrichment microfluidic chip for low-concentration liquid sample |
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181123 Termination date: 20200123 |