CN207923915U - Sample pipetting volume system and Ames test instrument - Google Patents
Sample pipetting volume system and Ames test instrument Download PDFInfo
- Publication number
- CN207923915U CN207923915U CN201820357657.7U CN201820357657U CN207923915U CN 207923915 U CN207923915 U CN 207923915U CN 201820357657 U CN201820357657 U CN 201820357657U CN 207923915 U CN207923915 U CN 207923915U
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- China
- Prior art keywords
- needle
- needle tubing
- injector
- changing device
- tubing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000010953 Ames test Methods 0.000 title claims abstract description 19
- 231100000039 Ames test Toxicity 0.000 title claims abstract description 19
- 239000007788 liquid Substances 0.000 claims abstract description 31
- 238000009434 installation Methods 0.000 claims abstract description 14
- 238000002474 experimental method Methods 0.000 abstract description 5
- 238000012864 cross contamination Methods 0.000 abstract description 3
- 238000002360 preparation method Methods 0.000 abstract description 2
- 230000007886 mutagenicity Effects 0.000 description 6
- 231100000299 mutagenicity Toxicity 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 238000001514 detection method Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 239000003344 environmental pollutant Substances 0.000 description 3
- 231100000719 pollutant Toxicity 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010007269 Carcinogenicity Diseases 0.000 description 1
- 235000002918 Fraxinus excelsior Nutrition 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 229940041181 antineoplastic drug Drugs 0.000 description 1
- 239000002956 ash Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000007670 carcinogenicity Effects 0.000 description 1
- 231100000260 carcinogenicity Toxicity 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000002361 compost Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000010842 industrial wastewater Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000003471 mutagenic agent Substances 0.000 description 1
- 231100000707 mutagenic chemical Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000010865 sewage Substances 0.000 description 1
- 239000010802 sludge Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Abstract
The utility model is related to sample pipetting volume system and Ames test instrument.Sample pipetting volume system includes：Rotating lifting gear；Holder；At least one needle changing device, each needle changing device have the connecting needle for being installed on holder；At least one container group, each container group include at least two first solution containers；At least one needle tubing group, each needle tubing group take liquid needle tubing including at least two；At least one rotating turret, it is each that liquid needle tubing is taken to be set to a placement installation position, each first solution container is set to a placement installation position, and each rotating turret is rotatably arranged with so that each placement installation position can be turned to the lower section of the connecting needle of a needle changing device thereon；And each needle changing device is configured to make to take liquid needle tubing to be mounted thereon below its connecting needle, or make to take liquid needle tubing to be detached from its connecting needle.The preparation of a variety of mixed liquors is can be achieved at the same time, and article cross contamination can be prevented, significantly improves the convenience and conventional efficient of experiment.
Description
Technical field
The utility model is related to Ames test technical field more particularly to a kind of sample pipetting volume system and there is the sample
The Ames test instrument of sample adding system.
Background technology
B.N.Ames etc. was established in 1975 through the effort of more than ten years and is continued to develop perfect salmonella back mutation reality
It tests（Also known as Ames experiments, Ames test）It is widely used by countries in the world.The method than faster, it is easy, sensitive, economical,
And it is suitable for test mixing thing, reflect the comprehensive effect of multiple pollutant.Detection food additives, makeup can be tested with Ames
Thus the mutagenicity of product etc. speculates its carcinogenicity；With Ames test detection Source water and drinking water mutagenicity, explore compared with
The relatively sanitary safe disinfectant measure of current methods；Or the mutagenicity of detection municipal sewage and industrial wastewater, in conjunction with chemistry point
Pollution sources are tracked in analysis, and foundation is provided for research Preventing Countermeasures；Detect the cause of soil, sludge, industrial residue compost, waste ashes
Mutability passes through the murrain mankind after preventing the soil for maintaining life from being polluted by mutagen；Detect gaseous pollutant
Mutagenicity, place pollutant via air, potential hazard occurred to human body by breathing；With Ames experimental study compounds
The relationship of structure and mutagenicity provides theoretical foundation for synthesis to noval chemical compound of the environment without potential hazard；Detection pesticide exists
Mutagenicity before and after microbial degradation, understanding pesticide, to the mankind, whether there is or not hidden danger in metabolic process after application；Also useful Ames
The anti-mutation-ure of experiment screening researchs and develops new anticancer drug etc..Existing Ames test is all experimenter using drop
Pipe adds reagent into culture dish, and the degree of automation is low, high labor cost, although can ensure certain experimental precision,
Experimental result deviation can be caused huge due to the error of people.
Utility model content
The purpose of the utility model is to provide a kind of sample pipetting volume systems, can be automatically by many kinds of substance according to predetermined
Amount be added to mixing test tube in mixed, the degree of automation, the cost of labor for significantly improving experiment are low, and experimental precision
Height, and the cross contamination of substance can be prevented, to realize that full-automatic Ames test instrument provides support.
For this purpose, the utility model provides a kind of sample pipetting volume system for Ames test instrument comprising：
Rotating lifting gear；
Holder is installed on the rotating lifting gear, to carry out up and down or rotation with the rotating lifting gear；
At least one needle changing device, each needle changing device have the connecting needle for being installed on the holder；
At least one container group, each container group include at least two first solution apptss；
At least one needle tubing group, each needle tubing group takes liquid needle tubing including at least two, and the number for taking liquid needle tubing
The quantity of first solution container of the amount container group corresponding to one is equal；
At least one rotating turret is each provided with multiple placement installation positions, to place or install one on the rotating turret
The needle tubing group and the container group corresponding with the needle tubing group, and each described take liquid needle tubing to be set to placements to pacify
Position is filled, each first solution container is set to a placement installation position, and each rotating turret is rotationally set
It sets, so that the lower section placed installation position and can be turned to the connecting needle of a needle changing device each of thereon；And
Each needle changing device be configured to make below its connecting needle it is described take liquid needle tubing to be mounted thereon, or make it
Liquid needle tubing is taken to be detached from described on connecting needle.
Optionally, further include：
At least one fixed needle tubing, is installed on the holder；
At least one second solution container, each second solution container are installed under a fixed needle tubing
Side.
Optionally, further include：
One injector and valve member, the injector is via the valve member and at least one needle changing device
Connecting needle be controllably connected to at least one fixed needle tubing；Or
Multiple injectors, the connecting needle or a fixed pin of each injector and a needle changing device
Pipe is connected to；Or
Multiple injectors and valve member, each injector and a needle changing device in the injector of part
Connecting needle or a fixed needle tubing connection；Each injector is via the valve in injector described in rest part
Door component is controllably connected to at least two in the connecting needle of needle changing device described in remaining and remaining described fixed needle tubing.
Optionally, the needle changing device is two, and the fixed needle tubing is three, and the injector is two, the valve
Door component is one；
One injector is connected to a fixed needle tubing, another described injector is via the valve member
It is controllably connected to needle tubing is fixed described in two needle changing devices and other two.
Optionally, at least one connecting needle and at least one fixed needle tubing and the rotating lifting gear
The distance between shaft is equal.
Optionally, each injector is plunger pump type injector.
Optionally, the rotating lifting gear includes：
Lifting platform；
Fixed column is installed on the lifting platform, to be risen or fallen with the lifting platform；
Rotating cylinder is rotatably installed on the fixed column；
Electric rotating machine is installed on the top of the fixed column, is configured to that the rotating cylinder is driven to rotate；And
The holder is installed on the upper end of the rotating cylinder.
The utility model additionally provides a kind of Ames test instrument comprising any of the above-described kind of sample pipetting volume system.
Because having needle changing device in the sample pipetting volume system and Ames test instrument of the utility model, can be achieved at the same time
The preparation of a variety of mixed liquors, and article cross contamination can be prevented, significantly improve the convenience and conventional efficient of experiment.And
And the sample pipetting volume system and the structure of Ames test instrument are simple, it is easy to control.
Description of the drawings
Hereinafter with reference to the accompanying drawings and embodiment mode and not restrictive be described in detail the utility model some are specific
Embodiment.Identical reference numeral denotes same or similar component or part in attached drawing.Those skilled in the art should manage
Solution, these attached drawings are not necessarily to scale drafting.
Fig. 1 is the schematic diagram according to the sample pipetting volume system of the utility model one embodiment.
Fig. 2 is the schematic diagram according to the Ames test instrument of the utility model one embodiment.
Specific implementation mode
To keep the purpose, technical scheme and advantage of the utility model embodiment clearer, below in conjunction with attached drawing to tool
Body embodiment is described in detail.In the utility model embodiment it should be noted that some pipelines in the example shown only by
Portions are shown, some pipelines are not expressed out in figure.
Fig. 1 is according to the schematic diagram of the sample pipetting volume system 60 of the utility model one embodiment, such as Fig. 1 institutes
Show, the utility model embodiment provides a kind of sample pipetting volume system 60 for Ames test instrument.The sample pipetting volume system
60 may include rotating lifting gear 61, holder 62, at least one needle changing device, at least one container group, at least one needle exchange group,
At least one rotating turret 66.
Holder 62 is installed on rotating lifting gear 61, to carry out up and down or rotation with rotating lifting gear 61.Each
Needle changing device has the connecting needle 63 for being installed on holder 62.Each container group includes at least two first solution containers 64.Often
A needle tubing group takes liquid needle tubing 65 including at least two, and takes the quantity of liquid needle tubing 65 to more than the first solution of corresponding container group and hold
The quantity of device 64 is equal.Be provided with multiple placement installation positions on each rotating turret 66, with place or install a needle tubing group and with
The corresponding container group of the needle tubing group, and liquid needle tubing 65 is each taken to be set to a placement installation position, each first solution container 64
It is set to a placement installation position, and each rotating turret 66 is rotatably arranged with so that each placement installation position can turn thereon
It moves to the lower section of the connecting needle 63 of a needle changing device.Each needle exchange sees that device is configured to make taking for its 63 lower section of connecting needle
Liquid needle tubing 65 is mounted thereon, or makes to take liquid needle tubing 65 to be detached from its connecting needle 63.
Sample pipetting volume system 60 in the utility model embodiment when in use, when needing replacing on a connecting needle 63
When taking liquid needle tubing 65, rotation one correspondingly rotate frame 66, turn on a current connecting needle 63 and take liquid needle tubing 65
At corresponding position, corresponding needle changing device makes to take liquid needle tubing 65 to be disconnected syringe needle 63 on connecting needle 63, falls down to corresponding
Placement installation position.Then rotating turret 66 is rotated further by the corresponding position to be mounted for taking liquid needle tubing 65, and holder 62 declines,
So that connecting needle 63 is inserted into the upper end for taking liquid needle tubing 65 of lower section, can make to take liquid needle tubing 65 to be installed on connecting needle by be mounted
63, the then rising of holder 62.Rotating turret 66 is rotated further by takes corresponding first solution of liquid needle tubing 65 to hold on connecting needle 63
At device 64, holder 62 declines, and can make that liquid needle tubing 65 is taken to take out desired solution.Next liquid needle tubing is taken likewise, needing replacing
When 65, above-mentioned action is repeated.
In some embodiments of the utility model, it is equal that sample pipetting volume system 60 will also add some all mixed liquors simultaneously
The solution that need to be used, therefore, the sample pipetting volume system 60 in the embodiment further include at least one fixed needle tubing 67 and at least one
A second solution container 68.Each fixed needle tubing 67 is installed on holder 62.Each second solution container 68 is installed on a fixation
The lower section of needle tubing 67.
In some embodiments of the utility model, for sample introduction, sample pipetting volume system 60 further includes an injector 69
And valve member, connecting needle 63 and at least one fixed pin of the injector 69 via valve member at least one needle changing device
The controlled connection of pipe 67.In other embodiments of the utility model, sample pipetting volume system 60 further includes multiple injectors 69,
Each injector 69 is connected to the connecting needle 63 of a needle changing device or a fixed needle tubing 67.
In some preferred embodiments of the utility model, sample pipetting volume system 60 further includes multiple injectors 69 and valve
Door component, each injector 69 and the connecting needle 63 of a needle changing device or a fixed company of needle tubing 67 in part injector 69
It is logical；Each injector 69 is via valve member and the connecting needle 63 of remaining needle changing device and remaining in rest part injector 69
At least two in fixed needle tubing 67 are controllably connected to.For example, needle changing device is two, fixed needle tubing 67 is three, injector
69 be two, and valve member is one.One injector 69 is connected to a fixed needle tubing 67, and another injector 69 is via valve
Component is fixed needle tubing 67 with two needle changing devices and other two and is controllably connected to.Each injector 69 be preferably plunger pump type into
Then sample device 69 makes to take liquid accordingly first to make to take the corresponding solution of sucking in liquid needle tubing 65 and/or fixed needle tubing 67 accordingly
Solution projects to the mixing test tube for receiving various solution in needle tubing 65 and/or fixed needle tubing 67.
In some embodiments of the utility model, in order to which mixing test tube for making the various solution of reception etc. is at same position
Various solution are received, between at least one connecting needle 63 and at least one fixed needle tubing 67 and the shaft of rotating lifting gear 61
Distance it is equal so that each take liquid needle tubing 65 and each fixed needle tubing 67 to can be turned to the surface of mixing test tube.Rotation
Lifting gear 61 may include lifting platform, fixed column, rotating cylinder, electric rotating machine.It is fixedly installed in lifting platform, to rise with lifting platform
Or decline.Rotating cylinder is rotatably installed on fixed column.Electric rotating machine is installed on the top of fixed column, is configured to drive rotating cylinder
Rotation；And holder 62 is installed on the upper end of rotating cylinder.
Fig. 2 is the schematic diagram according to the Ames test instrument of the utility model one embodiment, as shown in Fig. 2,
The utility model embodiment additionally provides a kind of Ames test instrument, may include the sample pipetting volume system in any of the above-described embodiment
System 60.
The above is only the preferred embodiment of the utility model, it is noted that for the common skill of the art
For art personnel, without departing from the principle of this utility model, made any improvements and modifications also should be regarded as this reality
With novel protection domain.
Claims (8)
1. a kind of sample pipetting volume system for Ames test instrument, which is characterized in that including：
Rotating lifting gear；
Holder is installed on the rotating lifting gear, to carry out up and down or rotation with the rotating lifting gear；
At least one needle changing device, each needle changing device have the connecting needle for being installed on the holder；
At least one container group, each container group include at least two first solution containers；
At least one needle tubing group, each needle tubing group take liquid needle tubing including at least two, and the quantity for taking liquid needle tubing and
The quantity of first solution container of one corresponding container group is equal；
At least one rotating turret is each provided with multiple placement installation positions, to place or install described in one on the rotating turret
Needle tubing group and the container group corresponding with the needle tubing group, and each described take liquid needle tubing to be set to placements to install
Position, each first solution container are set to a placement installation position, and each rotating turret rotatably arranged with,
So that each of the thereon lower section placed installation position and can be turned to the connecting needle of a needle changing device；And
Each needle changing device be configured to make below its connecting needle it is described take liquid needle tubing to be mounted thereon, or make its connection
Liquid needle tubing is taken to be detached from described on syringe needle.
2. sample pipetting volume system according to claim 1, which is characterized in that further include：
At least one fixed needle tubing, is installed on the holder；
At least one second solution container, each second solution container are installed on the lower section of a fixed needle tubing.
3. sample pipetting volume system according to claim 2, which is characterized in that further include：
One injector and valve member, the injector via the valve member and at least one needle changing device company
Syringe needle is connect controllably to be connected to at least one fixed needle tubing；Or
Multiple injectors, connecting needle or the fixed needle tubing company of each injector with needle changing device
It is logical；Or
Multiple injectors and valve member, the company of each injector and a needle changing device in the injector of part
Connect syringe needle or a fixed needle tubing connection；Each injector is via the valve group in injector described in rest part
Part is controllably connected to at least two in the connecting needle of needle changing device described in remaining and remaining described fixed needle tubing.
4. sample pipetting volume system according to claim 3, which is characterized in that
The needle changing device is two, and the fixed needle tubing is three, and the injector is two, and the valve member is one
It is a；
One injector is connected to a fixed needle tubing, and another injector is via the valve member and two
The needle changing device with fix needle tubing described in other two and be controllably connected to.
5. sample pipetting volume system according to claim 4, which is characterized in that
Between at least one connecting needle and at least one fixed needle tubing and the shaft of the rotating lifting gear
Apart from equal.
6. sample pipetting volume system according to claim 3, which is characterized in that
Each injector is plunger pump type injector.
7. sample pipetting volume system according to claim 1, which is characterized in that the rotating lifting gear includes：
Lifting platform；
Fixed column is installed on the lifting platform, to be risen or fallen with the lifting platform；
Rotating cylinder is rotatably installed on the fixed column；
Electric rotating machine is installed on the top of the fixed column, is configured to that the rotating cylinder is driven to rotate；And
The holder is installed on the upper end of the rotating cylinder.
8. a kind of Ames test instrument, which is characterized in that including the sample pipetting volume system described in any one of claim 1 to 7.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820357657.7U CN207923915U (en) | 2018-03-15 | 2018-03-15 | Sample pipetting volume system and Ames test instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820357657.7U CN207923915U (en) | 2018-03-15 | 2018-03-15 | Sample pipetting volume system and Ames test instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207923915U true CN207923915U (en) | 2018-09-28 |
Family
ID=63599378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820357657.7U Withdrawn - After Issue CN207923915U (en) | 2018-03-15 | 2018-03-15 | Sample pipetting volume system and Ames test instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207923915U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109959772A (en) * | 2019-03-13 | 2019-07-02 | 中国地质科学院水文地质环境地质研究所 | The in-situ monitoring experimental rig and method of soil eluviation |
| CN110275039A (en) * | 2018-03-15 | 2019-09-24 | 北京慧荣和科技有限公司 | Sample pipetting volume system and Ames test instrument |
-
2018
- 2018-03-15 CN CN201820357657.7U patent/CN207923915U/en not_active Withdrawn - After Issue
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110275039A (en) * | 2018-03-15 | 2019-09-24 | 北京慧荣和科技有限公司 | Sample pipetting volume system and Ames test instrument |
| CN110275039B (en) * | 2018-03-15 | 2024-02-20 | 北京慧荣和科技有限公司 | Sample application system and Ames experiment instrument |
| CN109959772A (en) * | 2019-03-13 | 2019-07-02 | 中国地质科学院水文地质环境地质研究所 | The in-situ monitoring experimental rig and method of soil eluviation |
| CN109959772B (en) * | 2019-03-13 | 2021-09-07 | 中国地质科学院水文地质环境地质研究所 | In-situ monitoring test device and method for soil leaching |
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| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20180928 Effective date of abandoning: 20240220 |
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| AV01 | Patent right actively abandoned |
Granted publication date: 20180928 Effective date of abandoning: 20240220 |