CN207780147U - A kind of sample needle imbibition state detection circuit - Google Patents
A kind of sample needle imbibition state detection circuit Download PDFInfo
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- CN207780147U CN207780147U CN201820010781.6U CN201820010781U CN207780147U CN 207780147 U CN207780147 U CN 207780147U CN 201820010781 U CN201820010781 U CN 201820010781U CN 207780147 U CN207780147 U CN 207780147U
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Abstract
The utility model discloses a kind of sample needle imbibition state detection circuit, including：The pressure sensor that is set on detected sample needle pipeline, the amplification module being amplified to the detection signal that pressure sensor exports, A/D conversion modules, forward voltage follow module, postposition voltage follow module, 15V power supplys and voltage conversion circuit.The detection circuit of the utility model carries out two level amplification to detection signal, and it is respectively provided with voltage follower circuit in amplification module input and output side, the accuracy for ensuring amplification module amplification benchmark reduces influence of the amplification output to late-class circuit, effectively improves sensitivity and the accuracy of detection circuit.
Description
Technical field
The utility model is related to the imbibition state detection circuits of the sample needle of in-vitro diagnosis equipment, belong to medical instrument neck
Domain.
Background technology
In-vitro diagnosis equipment during use, due to sample needle draw sample when can encounter suction, bubble, wadding
Situations such as shape object, grumeleuse, influences final result test data, to influence the accuracy and validity of experimental data.Cause
This, monitors the state of sample needle in real time, finds suction needle abnormal state in time and alarm immediately has very important significance.
Utility model content
The technical problems to be solved in the utility model is：The sample needle of existing in-vitro diagnosis equipment is not monitored, often free
The abnormal conditions such as suction, grumeleuse influence experimental result.For solution technical problem, a kind of sample needle imbibition state detection circuit is provided,
It can quickly, effectively detect the imbibition state and alarm of suction needle.
Technical solution adopted by the utility model to solve its technical problems is：
A kind of sample needle imbibition state detection circuit, including：
Pressure sensor is set on the pipeline of detected sample needle；
Amplification module is amplified the detection signal of pressure sensor output；
A/D conversion modules, output is to external control after carrying out A/D conversions to the detection signal amplified through the amplification module
Module；
Forward voltage follows module, is set between the pressure sensor and amplification module, and the pressure sensor is defeated
The detection signal gone out follows module to be input to amplification module by the forward voltage；
Postposition voltage follow module is set between the amplification module and the A/D conversion modules, the amplification module
The detection signal of the amplification of output is input to the A/D conversion modules by the postposition voltage follow module；
15V power supplys follow module and postposition voltage follow module to the amplification module, A/D conversion modules, forward voltage
Power supply is provided；
Voltage conversion circuit is set between the 15V power supplys and pressure sensor, is carried out to the output voltage of 15V power supplys
Convert and then be supplied to the pressure sensor.
Preferably, the amplification module includes that sequentially connected level-one amplification and two level amplification, the level-one are amplified same
Phase input terminal is connected with voltage follow module.
Preferably, the forward voltage follows module, level-one amplification and the voltage follow module respectively by an integrated fortune
Calculate four operational amplifier A 11-A14 and several resistance, capacitance and the adjustable resistance composition of amplification chip A1.
Preferably, the level-one is enlarged into the amplifying circuit of operational amplifier A 11 and resistance R3, capacitance C3, C4 composition；Institute
The positive and negative power end for stating operational amplifier A 11 is separately connected+15V, -15V power supply, and is grounded respectively by capacitance C3, C4；Institute
The inverting input for stating operational amplifier A 11 is connect by resistance R3 with its output end, in-phase input end connect the voltage with
With module.
Preferably, the voltage follow module is operational amplifier A 13 and resistance R1, R2, adjustable resistance VR1, Yi Ji electricity
Hold the voltage follower circuit of C7 compositions；The inverting input and its output end of the operational amplifier A 13 pass through resistance R5 simultaneously
It is connect with the in-phase input end of the operational amplifier A 11；The resistance R2, adjustable resistance VR1 and resistance R1 are sequentially connected in series structure
At bleeder circuit, which is separately connected+15V, -15V power supply；The in-phase input end of the operational amplifier A 13
It connect with the adjustable side of the adjustable resistance VR1, while being grounded by capacitance C7.
Preferably, it is two operational amplifier As 12, A14 and resistance R7, R8 composition that the forward voltage, which follows module,
Voltage follower circuit；
The in-phase input end of the operational amplifier A 12 is connect with the positive output end of the pressure sensor, anti-phase input
End is connect by resistance R7 with its output end, which passes through the operational amplifier A 11 of resistance R4 and level-one amplification again
Inverting input connection；
The in-phase input end of the operational amplifier A 14 is connect with the negative output terminal of the pressure sensor, anti-phase input
The in-phase input end for the operational amplifier A 11 that end and its output end are amplified by resistance R6 and the level-one simultaneously connect, passes through
Resistance R8 is connect with the inverting input of the operational amplifier A 12.
Preferably, the two level amplification and postposition voltage follow module are respectively by two of an integrated computation amplification chip A2
Operational amplifier A 21 and A22 and several resistance, capacitance, zener diode and adjustable resistance composition.
Preferably, the two level is enlarged into operational amplifier A 21 and resistance R10, R11, adjustable resistance VR2 and capacitance
The amplifying circuit of C5, C6 composition；The inverting input of the operational amplifier A 21 by resistance R11 and adjustable resistance VR2 with
The connection of its output end is connect by resistance R9 with the output end that the level-one is amplified, and in-phase input end is grounded by resistance R10；
The positive and negative power end of the operational amplifier A 21 is separately connected+15V, -15V power supply, and is grounded respectively by capacitance C5, C6.
Preferably, the postposition voltage follow module be operational amplifier A 22 and resistance R13-R17, adjustable resistance VR3 and
The voltage follower circuit of zener diode ZD1 compositions；The in-phase input end of the operational amplifier A 22 by resistance R13 ground connection,
The output end for the operational amplifier A 21 amplified by resistance R12 and the two level is connect；The reverse phase of the operational amplifier A 22
Input terminal is connect by resistance R15 with its output end, which is connect by resistance R17 with the A/D conversion modules again；Institute
State resistance R16 and adjustable resistance VR3 bleeder circuits in series, the resistance R16 other ends connection -15V power supplys, adjustable resistance
The VR3 other ends are grounded；It is also grounded by the zener diode ZD1 between the resistance R16 and adjustable resistance VR3；The fortune
The inverting input for calculating amplifier A22 is also connect by resistance R14 with the adjustable side of the adjustable resistance VR3.
Preferably, the voltage conversion circuit is made of a reference power supply chip with capacitance C1, C2；The reference power supply core
Input terminal connection+15V the power supplys of piece, while being grounded by capacitance C1；Its output end is connect with the pressure sensor, is led to simultaneously
Cross capacitance C2 ground connection.
The utility model has the beneficial effects that：
The sample needle imbibition state of in-vitro diagnosis equipment is monitored in real time, finds suction needle suction, bubble, wadding in time
The abnormalities such as shape object, grumeleuse are simultaneously alarmed immediately, carry out two level amplification to detection signal, and in amplification module input and output side
It is respectively provided with voltage follower circuit, it is ensured that amplification module amplifies the accuracy of benchmark, reduces shadow of the amplification output to late-class circuit
It rings, effectively improves sensitivity and the accuracy of detection circuit.
Description of the drawings
The utility model is further illustrated with reference to the accompanying drawings and examples.
Fig. 1 is the system structure diagram of the utility model detection circuit；
Fig. 2 is one embodiment schematic diagram of amplification module；
Fig. 3 is the circuit diagram of signal acquisition and amplification in the utility model detection circuit；
Fig. 4 is the circuit diagram of Fig. 3.
Reference numeral：10,15V power supplys；20, voltage conversion circuit；30, pressure sensor；40, forward voltage follows mould
Block；50, amplification module；51, level-one is amplified；52, two level is amplified；53, voltage follow module；60, postposition voltage follow module；
70, A/D conversion modules.
Specific implementation mode
The utility model is described in further detail presently in connection with attached drawing.These attached drawings are simplified schematic diagram,
Only illustrate the basic structure of the utility model in a schematic way, therefore it only shows composition related with the utility model.
Embodiment
The utility model provides a kind of sample needle imbibition state detection circuit of in-vitro diagnosis equipment, can rapidly detect
Sample needle state, timely and effective can judge whether sample needle the abnormal conditions such as suction, bubble, floccule, grumeleuse blocking occurs.
The detection circuit is that a pressure sensor is accessed in the detergent line of sample needle, when drawing sample and sample-adding spits liquid, is passed through
Pressure change in pressure sensor signal piping, and be compared with the pressure value under normal condition, whether judge sample needle
It is abnormal.
Specifically, as shown in Figure 1, the sample needle imbibition state detection circuit includes：It is set to detected sample-adding needle tubing
The pressure sensor 30 of road, amplification module 50, the A/D moduluss of conversion that the detection signal that pressure sensor 30 exports is amplified
Block 70, forward voltage follow module 40, postposition voltage follow module 60,15V power supplys 10 and voltage conversion circuit 20.Wherein, A/D
Output is to external control module after conversion module 70 carries out A/D conversions to the detection signal amplified through amplification module 50；Preposition electricity
Pressure follows module 40 to be set between pressure sensor 30 and amplification module 50, the detection signal that above-mentioned pressure sensor 30 exports
Module 40 is followed to be input to amplification module 50 by the forward voltage；Postposition voltage follow module 60 be set to amplification module 50 with
Between above-mentioned A/D conversion modules 70, the detection signal for the amplification that amplification module 50 exports passes through the postposition voltage follow module 60
It is input to A/D conversion modules 70；15V power supplys 10 follow module to above-mentioned amplification module 50, A/D conversion modules 70, forward voltage
40 and postposition voltage follow module 60 provide power supply；And voltage conversion circuit 20 is then set to above-mentioned 15V power supplys 10 and pressure sensing
Between device 30,10V voltages are exported after being converted to the output voltage of 15V power supplys 10, are available to pressure sensor 30.
Said external control module includes comparison circuit, warning circuit, master controller etc., the letter which is detected
Number it is compared judgement and abnormal alarm with the standard value under normal condition.Above-mentioned pressure sensor 30 is passed using analog pressure
Sensor, the preferably pressure sensor of Honeywell 26PC family chips U2 convert the pressure change generated in sample needle pipeline
For voltage change.When imbibition is normal, liquid flowing is unimpeded in pipeline, pressure sensor 30 generates a reference voltage；When adding
When sample needle needle mouth imbibition state changes, the pressure in pipeline can change, and the voltage of pressure sensor output can also be sent out
Changing.The voltage exported to pressure sensor 30 by amplification module 50 is amplified, and then amplified signal is carried out
A/D is converted, and analog voltage is converted into digital signal, external control module is transmitted further to and is compared judgement, final output
Judging result alarms etc. to abnormal conditions.For example, when sample needle touches liquid level and starts imbibition, the pressure in pipeline
Mutation is had, to which pressure signal can there are one mutation, after imbibition, the pressure recovery in pipeline, and a mutation is generated,
To form the pressure pulse of an imbibition.When sample needle is drawn onto floccule, grumeleuse, bubble or suction, pressure pulse
Duration and peak value of pulse under normal imbibition state burst length and peak value it is different.Such as when being drawn onto floccule, detection
The pressure pulse peak value arrived is than the peak value higher under normal imbibition state；When having grumeleuse, the pressure pulse time detected is longer；
When having bubble, the pressure pulse time detected is shorter；When suction, the pressure pulse peak value detected is very low.
As shown in Fig. 2, above-mentioned amplification module 50 includes sequentially connected level-one amplification 51 and two level amplification 52, above-mentioned level-one
The in-phase input end of amplification 51 is connected with voltage follow module 53, and the negative signal of 30 possible zero-bit of pressure sensor output is turned
It is changed to positive signal, and then can normally be amplified and A/D conversion operations, the measurement accuracy of entire detection circuit is improved.
Specifically, as shown in Figures 3 and 4, above-mentioned forward voltage follows module 40, level-one amplification 51 and voltage follow module 53
Respectively by the four operational amplifier A 11-A14 and several resistance, capacitance and adjustable resistance of an integrated computation amplification chip A1
Composition.
Specifically, as shown in figure 4, above-mentioned level-one amplification 51 is operational amplifier A 11 and resistance R3, capacitance C3, C4 are formed
Amplifying circuit.The positive and negative power end of the operational amplifier A 11 is separately connected+15V, -15V power supply, and passes through capacitance respectively
C3, C4 are grounded；The inverting input of operational amplifier A 11 is connect by resistance R3 with its output end, in-phase input end connection electricity
Pressure follows module.
Above-mentioned voltage follow module 53 is then operational amplifier A 13 and resistance R1, R2, adjustable resistance VR1 and capacitance C7
The voltage follower circuit of composition.The inverting input and its output end of the operational amplifier A 13 simultaneously by resistance R5 with it is above-mentioned
The in-phase input end of operational amplifier A 11 connects；Above-mentioned resistance R2, adjustable resistance VR1 and resistance R1 are followed in series to form partial pressure
Circuit, the bleeder circuit both ends are separately connected+15V, -15V power supply；The in-phase input end and adjustable resistance of operational amplifier A 13
The adjustable side of VR1 connects, while being grounded by capacitance C7.
Above-mentioned forward voltage follows module 40 for two operational amplifier As 12, the voltage of A14 and resistance R7, R8 composition
Follow circuit.Wherein, the in-phase input end of operational amplifier A 12 is connect with the positive output end of above-mentioned pressure sensor, and reverse phase is defeated
Enter end to connect with its output end by resistance R7, which passes through the operational amplifier of resistance R4 and above-mentioned level-one amplification 51 again
The inverting input of A11 connects.And the in-phase input end of operational amplifier A 14 is connect with the negative output terminal of pressure sensor 30,
Inverting input and its output end pass through the in-phase input end of resistance R6 and the operational amplifier A 11 of above-mentioned level-one amplification 51 simultaneously
Connection is connect by resistance R8 with the inverting input of operational amplifier A 12.
As shown in Figures 3 and 4, above-mentioned two level amplification 52 and postposition voltage follow module 60 amplify core by an integrated computation respectively
Two operational amplifier As 21 and A22 of piece A2 and several resistance, capacitance, zener diode and adjustable resistance composition.
Specifically, as shown in figure 4, above-mentioned two level amplification 52 is operational amplifier A 21 and resistance R10, R11, adjustable resistance
The amplifying circuit of VR2 and capacitance C5, C6 composition.The inverting input of the operational amplifier A 21 passes through resistance R11 and can
It adjusts resistance VR2 to be connect with its output end, connect with the output end of level-one amplification 51 by resistance R9, in-phase input end passes through
Resistance R10 ground connection；The positive and negative power end of operational amplifier A 21 is separately connected+15V, -15V power supply, and respectively by capacitance C5,
C6 is grounded.
Above-mentioned postposition voltage follow module 60 is operational amplifier A 22 and resistance R13-R17, adjustable resistance VR3 and voltage stabilizing
The voltage follower circuit of diode ZD1 compositions.The in-phase input end of the operational amplifier A 22 is grounded by resistance R13, passes through electricity
Resistance R12 is connect with the output end for the operational amplifier A 21 that above-mentioned two level is amplified；The inverting input of operational amplifier A 22 passes through
Resistance R15 is connect with its output end, which is connect by resistance R17 with above-mentioned A/D conversion modules 70 again；Resistance R16 and
Adjustable resistance VR3 bleeder circuits in series, resistance R16 other end connection -15V power supplys, adjustable resistance VR3 other ends ground connection；
It is also grounded by above-mentioned zener diode ZD1 between resistance R16 and adjustable resistance VR3；The anti-phase input of the operational amplifier A 22
End is also connect by resistance R14 with the adjustable side of adjustable resistance VR3.
As shown in Figures 3 and 4, above-mentioned voltage conversion circuit 20 is made of a reference power supply chip U1 and capacitance C1, C2.The base
Input terminal connection+15V the power supplys of quasi- power supply chip U1, while being grounded by capacitance C1；Its output end connects with pressure sensor 30
It connects, while being grounded by capacitance C2.
Above-mentioned detection circuit monitors the sample needle imbibition state of in-vitro diagnosis equipment in real time, finds suction needle in time
The abnormalities such as suction, bubble, floccule, grumeleuse are simultaneously alarmed immediately, carry out two level amplification to detection signal, and in amplification module
Input and output side is respectively provided with voltage follower circuit, it is ensured that amplification module amplifies the accuracy of benchmark, reduces amplification output pair
The influence of late-class circuit effectively improves sensitivity and the accuracy of detection circuit.
It is enlightenment, through the above description, related work people with the above-mentioned desirable embodiment according to the utility model
Member can carry out various changes and amendments in the range of without departing from this item utility model technological thought completely.This item is real
It is not limited to the contents of the specification with novel technical scope, it is necessary to which its technology is determined according to right
Property range.
Claims (10)
1. a kind of sample needle imbibition state detection circuit, which is characterized in that including：
Pressure sensor is set on the pipeline of detected sample needle；
Amplification module is amplified the detection signal of pressure sensor output；
A/D conversion modules, output is to external control mould after carrying out A/D conversions to the detection signal amplified through the amplification module
Block；
Forward voltage follows module, is set between the pressure sensor and amplification module, the pressure sensor output
Detection signal follows module to be input to amplification module by the forward voltage；
Postposition voltage follow module is set between the amplification module and the A/D conversion modules, the amplification module output
The detection signal of amplification the A/D conversion modules are input to by the postposition voltage follow module；
15V power supplys follow module and postposition voltage follow module to provide to the amplification module, A/D conversion modules, forward voltage
Power supply；
Voltage conversion circuit is set between the 15V power supplys and pressure sensor, is converted to the output voltage of 15V power supplys
And then it is supplied to the pressure sensor.
2. sample needle imbibition state detection circuit according to claim 1, it is characterised in that：The amplification module include according to
The level-one amplification and two level amplification of secondary connection, the in-phase input end of the level-one amplification are connected with voltage follow module.
3. sample needle imbibition state detection circuit according to claim 2, it is characterised in that：The forward voltage follows mould
Block, level-one amplification and the voltage follow module are respectively by four operational amplifier A 11- of an integrated computation amplification chip A1
A14 and several resistance, capacitance and adjustable resistance composition.
4. sample needle imbibition state detection circuit according to claim 3, it is characterised in that：The level-one is enlarged into operation
The amplifying circuit of amplifier A11 and resistance R3, capacitance C3, C4 composition；The positive and negative power end of the operational amplifier A 11 is distinguished
Connection+15V, -15V power supplys, and be grounded respectively by capacitance C3, C4；The inverting input of the operational amplifier A 11 passes through electricity
Resistance R3 is connect with its output end, and in-phase input end connects the voltage follow module.
5. sample needle imbibition state detection circuit according to claim 4, it is characterised in that：The voltage follow module is
Operational amplifier A 13 and resistance R1, R2, adjustable resistance VR1 and the voltage follower circuit of capacitance C7 compositions；The operation is put
The inverting input and its output end of big device A13 is connected by resistance R5 and the in-phase input end of the operational amplifier A 11 simultaneously
It connects；The resistance R2, adjustable resistance VR1 and resistance R1 are followed in series to form bleeder circuit, which is separately connected
+ 15V, -15V power supply；The in-phase input end of the operational amplifier A 13 is connect with the adjustable side of the adjustable resistance VR1, simultaneously
It is grounded by capacitance C7.
6. sample needle imbibition state detection circuit according to claim 4, it is characterised in that：The forward voltage follows mould
The voltage follower circuit that block is two operational amplifier As 12, A14 and resistance R7, R8 are formed；
The in-phase input end of the operational amplifier A 12 is connect with the positive output end of the pressure sensor, and inverting input is logical
Resistance R7 is crossed to connect with its output end, the operational amplifier A 11 which is amplified by resistance R4 and the level-one again it is anti-
Phase input terminal connects；
The in-phase input end of the operational amplifier A 14 is connect with the negative output terminal of the pressure sensor, inverting input and
The in-phase input end for the operational amplifier A 11 that its output end is amplified by resistance R6 and the level-one simultaneously connect, passes through resistance
R8 is connect with the inverting input of the operational amplifier A 12.
7. sample needle imbibition state detection circuit according to claim 2, it is characterised in that：The two level amplification and postposition
Voltage follow module is respectively by two operational amplifier As 21 and A22 and several resistance, electricity of an integrated computation amplification chip A2
Hold, zener diode and adjustable resistance form.
8. sample needle imbibition state detection circuit according to claim 7, it is characterised in that：The two level is enlarged into operation
Amplifier A21 and resistance R10, R11, adjustable resistance VR2 and the amplifying circuit of capacitance C5, C6 composition；The operational amplifier
The inverting input of A21 is connect by resistance R11 and adjustable resistance VR2 with its output end, by resistance R9 and the level-one
The output end of amplification connects, and in-phase input end is grounded by resistance R10；The positive and negative power end of the operational amplifier A 21 is distinguished
Connection+15V, -15V power supplys, and be grounded respectively by capacitance C5, C6.
9. sample needle imbibition state detection circuit according to claim 8, it is characterised in that：The postposition voltage follow mould
Block is the voltage follower circuit of operational amplifier A 22 and resistance R13-R17, adjustable resistance VR3 and zener diode ZD1 compositions；
The in-phase input end of the operational amplifier A 22 is grounded by resistance R13, passes through the operation of resistance R12 and two level amplification
The output end of amplifier A21 connects；The inverting input of the operational amplifier A 22 is connect by resistance R15 with its output end,
The output end is connect by resistance R17 with the A/D conversion modules again；The resistance R16 and in series point of adjustable resistance VR3
Volt circuit, the resistance R16 other ends connection -15V power supplys, adjustable resistance VR3 other ends ground connection；The resistance R16 with it is adjustable
It is also grounded by the zener diode ZD1 between resistance VR3；The inverting input of the operational amplifier A 22 also passes through electricity
Resistance R14 is connect with the adjustable side of the adjustable resistance VR3.
10. according to claim 1-9 any one of them sample needle imbibition state detection circuits, it is characterised in that：The voltage
Translation circuit is made of a reference power supply chip with capacitance C1, C2；Input terminal connection+15V the power supplys of the reference power supply chip,
It is grounded simultaneously by capacitance C1；Its output end is connect with the pressure sensor, while being grounded by capacitance C2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820010781.6U CN207780147U (en) | 2018-01-04 | 2018-01-04 | A kind of sample needle imbibition state detection circuit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820010781.6U CN207780147U (en) | 2018-01-04 | 2018-01-04 | A kind of sample needle imbibition state detection circuit |
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| Publication Number | Publication Date |
|---|---|
| CN207780147U true CN207780147U (en) | 2018-08-28 |
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ID=63223729
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| CN201820010781.6U Active CN207780147U (en) | 2018-01-04 | 2018-01-04 | A kind of sample needle imbibition state detection circuit |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109669034A (en) * | 2018-12-21 | 2019-04-23 | 苏州长光华医生物医学工程有限公司 | Liquid bottle liquid inspection system and its application method |
| CN111024972A (en) * | 2019-12-11 | 2020-04-17 | 桂林优利特医疗电子有限公司 | Method and device for detecting sample suction state of sample adding needle in real time |
-
2018
- 2018-01-04 CN CN201820010781.6U patent/CN207780147U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109669034A (en) * | 2018-12-21 | 2019-04-23 | 苏州长光华医生物医学工程有限公司 | Liquid bottle liquid inspection system and its application method |
| CN111024972A (en) * | 2019-12-11 | 2020-04-17 | 桂林优利特医疗电子有限公司 | Method and device for detecting sample suction state of sample adding needle in real time |
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