CN207755415U - A kind of reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus - Google Patents
A kind of reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus Download PDFInfo
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- CN207755415U CN207755415U CN201720659598.4U CN201720659598U CN207755415U CN 207755415 U CN207755415 U CN 207755415U CN 201720659598 U CN201720659598 U CN 201720659598U CN 207755415 U CN207755415 U CN 207755415U
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- clamp arm
- activity clamp
- reproducible
- gradable
- activity
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- 230000000694 effects Effects 0.000 claims abstract description 65
- 230000005540 biological transmission Effects 0.000 claims abstract description 10
- 230000007246 mechanism Effects 0.000 claims abstract description 10
- 238000006073 displacement reaction Methods 0.000 claims abstract description 6
- 208000020431 spinal cord injury Diseases 0.000 abstract description 14
- 230000006378 damage Effects 0.000 description 15
- 241001465754 Metazoa Species 0.000 description 10
- 208000027418 Wounds and injury Diseases 0.000 description 9
- 208000014674 injury Diseases 0.000 description 6
- 210000000278 spinal cord Anatomy 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 4
- 238000011160 research Methods 0.000 description 3
- 238000004088 simulation Methods 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 206010061213 Iatrogenic injury Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 208000037273 Pathologic Processes Diseases 0.000 description 1
- 241000135309 Processus Species 0.000 description 1
- 208000020339 Spinal injury Diseases 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 230000007659 motor function Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 238000011587 new zealand white rabbit Methods 0.000 description 1
- 230000009054 pathological process Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000003362 replicative effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
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Abstract
The utility model discloses a kind of reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus, including fixing clamp arm and activity clamp arm, the bottom of fixing clamp arm and activity clamp arm all has two collets for backbone to be clamped, two guide rods disposed in parallel are equipped between fixing clamp arm and activity clamp arm, fixing clamp arm is fixedly connected with two guide rods, activity clamp arm is slidedly assemblied on two guide rods, it is additionally provided with lead screw transmission mechanism between two guide rods and activity clamp arm, lead screw transmission mechanism include screw rod and and fixed block, fixed block is fixedly connected on two guide rods, screw rod spiral from fixed block is pierced by be fixedly connected with activity clamp arm, the scale for measuring activity clamp arm displacement is fixed between fixed block and fixing clamp arm.The utility model is moved using lead screw transmission mechanism drive activity clamp arm, and the displacement distance of activity clamp arm can directly be read by scale.The utility model can simulate tractive spinal cord injury, have the advantages that reproducible, gradable, closed is good.
Description
Technical field
The utility model is related to a kind of animal experimental model, specifically a kind of reproducible, gradable and quantitative reality
The property tested closed backbone Distraction Apparatus.
Background technology
Spinal cord stretch injury is common in the iatrogenic injury in spinal trauma or spine corrective operation, is a kind of serious
Complication.Spinal cord stretch injury has caused the note of domestic and international researcher because of caused by overstretching backbone in orthomorphia
Meaning, the important directions that researcher studies are how to protect myeloid tissue, effective maimed, promotion damage spinal cord after mitigating wound
The reconstruction of function.How to establish there are one degree of impairment, repeatable animal model can be simulated, makes the pathologic process of spinal injury
It is a problem of current spinal cord injury research with reproducible to animal.The prior art has a kind of experiment of spinal cord stretch injury
Device can simulate spinal cord injury by rat, but the device is inconvenient, and stability is poor during backbone struts, cannot
Classification, is not easy to DATA REASONING, closed is poor.
Invention content
The purpose of this utility model is to provide a kind of the reproducible, gradable of tractive spinal cord injury and fixed of capable of simulating
The experimental closed backbone Distraction Apparatus of amount.
The utility model adopts the following technical solution：A kind of reproducible, gradable and quantitative experimental closed backbone
The bottom of Distraction Apparatus, including fixing clamp arm and activity clamp arm, fixing clamp arm and activity clamp arm all has two for backbone to be clamped
Collet, two guide rods disposed in parallel are equipped between fixing clamp arm and activity clamp arm, fixing clamp arm is fixed with two guide rods to be connected
It connecing, activity clamp arm is slidedly assemblied on two guide rods, and lead screw transmission mechanism is additionally provided between described two guide rods and activity clamp arm,
Lead screw transmission mechanism includes screw rod and is fixedly connected on two guide rods with fixed block, fixed block, screw rod spiral from fixed block
It is fixedly connected, is fixed between the fixed block and fixing clamp arm for measuring activity clamp arm displacement with activity clamp arm after being pierced by
Scale.
The activity clamp arm is between fixing clamp arm and fixed block.
The fixing clamp arm between activity clamp arm and fixed block, screw rod spiral from fixed block be pierced by after first from
It is pierced by fixing clamp arm and is fixedly connected again with activity clamp arm, the scale extends to the movement of activity clamp arm most from fixing clamp arm
Distally.
The fixing clamp arm and activity clamp arm include two symmetrically arranged vertical arm, and two vertical arm are solid by bolt
Surely it links together, gripping sleeve is equipped with outside two vertical arm, the collet is arranged in the bottom end of vertical arm.
It is arc surface on the inside of the collet.
Described two guide rods are between the upper and lower every setting.
The screw rod rotation is turned around, and the distance of activity clamp arm movement is 1 millimeter, and the precision of the scale is 0.5 millimeter.
Anti-skidding raised line is equipped on the inside of the collet.
The end of the screw rod is equipped with the hexagonal (hexagon)nut with handle.
The utility model has the beneficial effects that：When the utility model is used, the collet of fixing clamp arm and activity clamp arm is just
It encircles in animal centrum both sides, to clamp animal centrum, fixing clamp arm is fixed on two guide rods and remains stationary as always, profit
It is moved with lead screw transmission mechanism drive activity clamp arm, activity clamp arm can move back and forth with the rotation of screw rod, the shifting of activity clamp arm
Dynamic distance can directly be read by scale.Backbone when activity clamp arm moves between two clamp arm is softened as required.By dynamic
Object experiment shows that this model of the utility model not only belongs to " closed ", and simulation injury pattern is damaged closer to clinical spinal cord
The situation of wound, the duplication damage results with preferable damage quantitative ability and graded properties, when experiment, give a certain amount of load
The corresponding damage of the load can be generated, the utility model is easy to use, reliable, wound is smaller, can be classified and damage out difference
The spinal cord injury of rank does not carry out comparative study convenient for grouping, is very suitable for acute or chronic experimental study.The utility model can
With extraordinary simulation tractive spinal cord injury, have the advantages that reproducible, gradable, closed is good.This is further research
Tractive spinal cord injury provides an ideal animal experimental model.
Further, the distance between two vertical arm can be adjusted by bolt, so as to according to animal vertebra
Thickness adjusts the distance of the collet of fixing clamp arm and activity clamp arm.
Further, the precision of scale is 0.5 millimeter, and screw rod rotation is turned around, and the distance of activity clamp arm adjustment is 1 millimeter,
The distance of screw rod half rotation activity clamp arm adjustment is exactly 0.5 millimeter, can make damage load is small to be accurate to 0.5 millimeter in this way.
Further, the anti-skidding raised line on the inside of collet ensures that instrument does not generate sliding during backbone struts.
It further, can convenient rotary screw by hexagonal (hexagon)nut of the rotation with handle.
Description of the drawings
Fig. 1 is the structural schematic diagram of the utility model embodiment 1；
Fig. 2 is the plan view of Fig. 1.
Specific implementation mode
The utility model is described in detail in the following with reference to the drawings and specific embodiments.
The structure of the utility model embodiment 1 is as shown in Figure 1 to Figure 2, the present embodiment it is reproducible, gradable and quantitative
The bottom of experimental closed backbone Distraction Apparatus, including fixing clamp arm 1 and activity clamp arm 2, fixing clamp arm 1 and activity clamp arm 2 is equal
For tool there are two the collet 11 for backbone to be clamped, 11 inside of collet is arc surface, and 11 inside of collet is equipped with anti-skidding raised line（In attached drawing
It does not show）.The fixing clamp arm 1 and activity clamp arm 2 include two symmetrically arranged vertical arm 12, and two vertical arm 12 pass through
Bolt 7 is fixed together, and two 12 outsides of vertical arm are equipped with gripping sleeve 8, and the collet 11 is arranged at the bottom of vertical arm 12
End.Two guide rods 3 disposed in parallel are equipped between fixing clamp arm 1 and activity clamp arm 2, two guide rods 3 are fixed between the upper and lower every setting
Clamp arm 1 is fixedly connected with two guide rods 3, and activity clamp arm 2 is slidedly assemblied on two guide rods 3, and described two guide rods 3 and activity are pressed from both sides
Be additionally provided with lead screw transmission mechanism between arm 2, lead screw transmission mechanism include screw rod 4 and with fixed block 5, fixed block 5 is fixedly connected on
On two guide rods 3, screw rod 4 is pierced by from spiral on fixed block 5 and is fixedly connected afterwards with activity clamp arm 2, the fixed block 5 and geometrical clamp
The scale 6 for measuring activity clamp arm displacement is fixed between arm 1.The end of the screw rod 4 is equipped with the hexagonal spiral shell with handle
Cap 9.In the present embodiment, activity clamp arm 2 is between fixing clamp arm 1 and fixed block 5.The screw rod rotation is turned around, activity clamp arm
Mobile distance is 1 millimeter, and the precision of the scale is 0.5 millimeter.
When the present embodiment is in use, entire Distraction Apparatus is suspended on the metallic support of adjustable up-down, adjusts fixing clamp arm
With the bolt in activity clamp arm, two collets of each clamp arm is made just to encircle the circular arc on the inside of animal centrum both sides, collet
Face clamps animal centrum, and anti-skidding raised line ensures that instrument does not generate sliding during backbone struts.Fixing clamp arm is fixed always
It is remained stationary as on two guide rods, activity clamp arm can move back and forth with the rotation of screw rod, and the displacement distance of activity clamp arm can lead to
Scale is crossed directly to read.Screw rod rotation is turned around, and the distance of activity clamp arm adjustment is 1 millimeter, screw rod half rotation activity clamp arm tune
Whole distance is exactly 0.5 millimeter, can make damage load is small to be accurate to 0.5 millimeter in this way.Two clamp arm when activity clamp arm moves
Between backbone be softened as required.
Aseptically, make an animal from T10-L4 vertebra planes（New zealand white rabbit）Back median incision is cut
Skin detaches both sides paraspinal muscle at T12 and L4 centrums, appears the both sides of entire attachment and centrum, with thousand points respectively with subcutaneously
Vernier caliper measurement L1-L4 centrum processus articular superior spacing, and add physical lengths of the 2mm as L1-L3 spinal segments.Stretching
The fixing clamp arm and activity clamp arm of device fix T12 and L4 centrums respectively, and make a bone mark respectively, it is ensured that backbone is distracted to be had
Effect carries out.
15 minutes after Distraction Apparatus placement, rotary screw makes activity clamp arm move, and struts 2.5mm every time, is completed in 30 seconds,
Interval 5 minutes struts always 10%, 20%, the 30% of L1-L3 spinal segments length and maintains 10 minutes, then rapid to take out
Distraction Apparatus.I.e. it is believed that 10% tractive spinal cord injury, 20% tractive spinal cord injury, 30% tractive spinal cord injury.
Experimenter by means of the Distraction Apparatus of the present embodiment on the basis of rabbit L1-L3 spinal segments length, by 10% group,
It is 20% group and 30% group, experimental it is expected to establish with 0.25cm/5min speed strutting to T12 and L4 centrums progress 0-30%
Tractive spinal cord injury model, and it is subject to qualitative and quantitative pathology form and motor function evaluation to replicating result.As a result table
Bright, for simulation injury pattern closer to the situation of clinical spinal cord injury, i.e. this model do not only belong to " closed ", this mould
The type also duplication damage results with preferable damage quantitative ability and graded properties, when experiment, which gives a certain amount of load, to produce
The corresponding damage of the life load, can be classified the spinal cord injury for damaging out different stage, and comparative study is not carried out convenient for grouping.This
Utility model is easy to use, reliable, wound is smaller, can be suitble to acute or chronic experimental study.This is further research stretching
Spinal cord injury provides an ideal animal experimental model.
The utility model embodiment 2 as different from Example 1, fixing clamp arm between activity clamp arm and fixed block,
The screw rod is first pierced by from fixing clamp arm and is fixedly connected again with activity clamp arm after being pierced by from spiral on fixed block, the scale from
The distalmost end of activity clamp arm movement is extended at fixing clamp arm.The present embodiment other structures are same as Example 1.Due to embodiment
2 is similar with the structure of embodiment 1, difference place very little, therefore omits the attached drawing of embodiment 2.
In the other embodiments of the utility model, two guide rods can also be arranged in parallel in same level, as long as two
Root guide rod is arranged in parallel.
Above-described embodiment is the utility model preferred embodiment, in the premise for not departing from the spirit and scope of the utility model
Under, the utility model also has various changes and improvements, these changes and improvements both fall within claimed the utility model model
In enclosing.The protection scope of the present invention is defined by the appended claims and their equivalents.
Claims (9)
1. a kind of reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus, it is characterised in that：Including fixing clamp arm
（1）With activity clamp arm（2）, fixing clamp arm（1）With activity clamp arm（2）Bottom all have two for the collets of backbone to be clamped
（11）, fixing clamp arm（1）With activity clamp arm（2）Between be equipped with two guide rods disposed in parallel（3）, fixing clamp arm（1）With two
Guide rod（3）It is fixedly connected, activity clamp arm（2）It is slidedly assemblied in two guide rods（3）On, described two guide rods（3）With activity clamp arm
（2）Between be additionally provided with lead screw transmission mechanism, lead screw transmission mechanism includes screw rod（4）With with fixed block（5）, fixed block（5）It is fixed
It is connected to two guide rods（3）On, screw rod（4）From fixed block（5）Upper spiral is pierced by rear and activity clamp arm（2）It is fixedly connected, it is described
Fixed block（5）And fixing clamp arm（1）Between be fixed with scale for measuring activity clamp arm displacement（6）.
2. reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus according to claim 1, feature exist
In：The activity clamp arm（2）Positioned at fixing clamp arm（1）And fixed block（5）Between.
3. reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus according to claim 1, feature exist
In：The fixing clamp arm（1）Positioned at activity clamp arm（2）And fixed block（5）Between, the screw rod（4）From fixed block（5）Upper spiral
First from fixing clamp arm after being pierced by（1）In be pierced by again with activity clamp arm（2）It is fixedly connected, the scale（6）From fixing clamp arm（1）Place
Extend to activity clamp arm（2）Mobile distalmost end.
4. reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus according to claim 1 or 2 or 3,
It is characterized in that：The fixing clamp arm（1）With activity clamp arm（2）Include two symmetrically arranged vertical arm（12）, two vertical
Arm（12）Pass through bolt（7）It is fixed together, two vertical arm（12）Outside is equipped with gripping sleeve（8）, the collet（11）
It is arranged in vertical arm（12）Bottom end.
5. reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus according to claim 4, feature exist
In：The collet（11）Inside is arc surface.
6. reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus according to claim 4, feature exist
In：Described two guide rods（3）Between the upper and lower every setting.
7. reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus according to claim 1 or 2 or 3,
It is characterized in that：The screw rod rotation is turned around, and the distance of activity clamp arm movement is 1 millimeter, and the precision of the scale is 0.5 millimeter.
8. reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus according to claim 1 or 2 or 3,
It is characterized in that：The collet（11）Inside is equipped with anti-skidding raised line.
9. reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus according to claim 1 or 2 or 3,
It is characterized in that：The screw rod（4）End be equipped with handle hexagonal (hexagon)nut（9）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720659598.4U CN207755415U (en) | 2017-06-08 | 2017-06-08 | A kind of reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720659598.4U CN207755415U (en) | 2017-06-08 | 2017-06-08 | A kind of reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus |
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| Publication Number | Publication Date |
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| CN207755415U true CN207755415U (en) | 2018-08-24 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720659598.4U Expired - Fee Related CN207755415U (en) | 2017-06-08 | 2017-06-08 | A kind of reproducible, gradable and quantitative experimental closed backbone Distraction Apparatus |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110169839A (en) * | 2019-05-29 | 2019-08-27 | 上海塔望智能科技有限公司 | A kind of animal spinal cord injury test macro |
| CN112216192A (en) * | 2020-10-09 | 2021-01-12 | 中国人民解放军空军军医大学 | Device and method for simulating + Gz and WBV environments in flight state |
-
2017
- 2017-06-08 CN CN201720659598.4U patent/CN207755415U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110169839A (en) * | 2019-05-29 | 2019-08-27 | 上海塔望智能科技有限公司 | A kind of animal spinal cord injury test macro |
| CN112216192A (en) * | 2020-10-09 | 2021-01-12 | 中国人民解放军空军军医大学 | Device and method for simulating + Gz and WBV environments in flight state |
| CN112216192B (en) * | 2020-10-09 | 2024-05-24 | 中国人民解放军空军军医大学 | Device and method for simulating +Gz and WBV environments in flight state |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190202 Address after: 100142 Air Force Characteristic Medical Center, 30 Fucheng Road, Haidian District, Beijing Patentee after: Chinese People's Liberation Army Air Force Characteristic Medical Center Address before: 100142 Air Force General Hospital No. 30 Fucheng Road, Haidian District, Beijing Co-patentee before: Wu Di Patentee before: Wu Ji Co-patentee before: Zheng Chao Co-patentee before: Huang Rongrong |
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| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180824 Termination date: 20190608 |
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| CF01 | Termination of patent right due to non-payment of annual fee |