CN207730744U - A kind of drug dissolution tester - Google Patents
A kind of drug dissolution tester Download PDFInfo
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- CN207730744U CN207730744U CN201721765719.XU CN201721765719U CN207730744U CN 207730744 U CN207730744 U CN 207730744U CN 201721765719 U CN201721765719 U CN 201721765719U CN 207730744 U CN207730744 U CN 207730744U
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- water bath
- rack
- stripping rotor
- fixedly connected
- drug dissolution
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Abstract
The utility model is related to medicinal detection device fields, disclose a kind of drug dissolution tester, including rack, it is characterized in that：Two set detecting devices are provided in the rack, the detection device is located at the both sides of the rack, the detection device includes the water bath being slidably connected in the rack, is placed in the water bath stripping rotor, the mounting bracket being connected on the water bath, the head on the mounting bracket, the agitating paddle being fixedly connected on the head, the driving water bath movement drive component, the agitating paddle is located in the stripping rotor, and the utility model has the following advantages and effect：This programme utilizes new mechanical structure, by the way that detection device is arranged so that testing staff can be carried out at the same time detection in both sides, and testing staff is not easy to generate interference mutually when extracting liquid, improves the efficiency of detection.
Description
Technical field
The utility model is related to a kind of medicinal detection devices, more specifically, it relates to a kind of drug dissolution tester.
Background technology
Medicine dissolving out experimental instrument（Abbreviation digestion instrument）It is used exclusively for detection oral solid formulation（Such as tablet, capsule, particle
Agent etc.）The drug test instrument of dissolution rate.It can simulate the gastroenteric environment and digestion motion process of human body, be a kind of control drug
The in vitro test device of preparation is widely used in the research, production and inspection of drug.
Currently, the Chinese patent that notification number is CN205941274U discloses a kind of dissolving-out tester, it includes head, machine
Head has the first opposite side and the second side, and multiple bull sticks, head are arranged at intervals with along the direction of head the first side to the second side
The first side and the second side be both provided with vertical inclined sliding slot, two runner positions it is opposite and respectively sliding be equipped with connecting rod, two
Root connecting rod extends downward into close to water bath and is connected with pallet for accepting drop.This dissolving-out tester is connected by being arranged
Bar, linkage pallet movement, pallet are collected the drop that bull stick is taken out of, if but the shared dissolution test of multiple testing staff
Instrument, the drug that testing staff is difficult to detect oneself distinguish, and when one of testing staff carries out to liquid
It can hinder another testing staff to the extraction of liquid when extraction, reduce the efficiency of detection.
Utility model content
In view of the deficienciess of the prior art, the utility model lies in that providing a kind of drug dissolution tester, has and carry
The effect of high detection efficiency.
To achieve the above object, the utility model provides following technical solution：A kind of drug dissolution tester, including
Rack, it is characterized in that：Two set detecting devices are provided in the rack, the detection device is located at the both sides of the rack, institute
Detection device is stated to include the water bath being slidably connected in the rack, the stripping rotor that is placed in the water bath, be connected to
Mounting bracket on the water bath, the agitating paddle being fixedly connected on the head, drives the head on the mounting bracket
The drive component of the dynamic water bath movement, the agitating paddle are located in the stripping rotor.
By using above-mentioned technical proposal, when the testing staff of wherein side needs to extract the liquid in stripping rotor
When, testing staff drives water bath to move by drive component, and water bath movement drives mounting bracket movement so that water bath and peace
It shelves while far from rack, testing staff can extract the liquid in stripping rotor, when the testing staff of the other side needs
When carrying out Liquid extracting, testing staff can extract the liquid in stripping rotor by the detection device of the other side so that inspection
It is not easy to interfere with each other between survey personnel operation, and facilitates the operation of testing staff, improve the monitoring efficiency of testing staff.
The utility model is further arranged to：The driving component includes the driving motor being mounted in the rack, consolidates
Surely be connected in the driving motor output shaft driving gear, the drive rack that is slidably connected in the rack, the drive
Carry-over bar is engaged with the driving gear.
By using above-mentioned technical proposal, driving motor drives the rotation of sliding tooth wheel, the rotation of sliding tooth wheel to drive sliding tooth
Item moves, and drive rack movement drives water bath movement, water bath movement to drive mounting bracket movement so that water bath and mounting bracket
Leave rack simultaneously so that testing staff conveniently carries out the extraction of liquid.
The utility model is further arranged to：The mounting bracket is connect by connector with the water bath, the connection
Part includes the fixed plate being fixedly connected on the water bath, is fixedly connected on the mounting bracket sliding shoe is opened in institute
The sliding groove in fixed plate is stated, the sliding shoe is slided along the length direction of the sliding groove.
By using above-mentioned technical proposal, testing staff drives mounting bracket to move, and mounting bracket moves so that sliding shoe is along sliding
Dynamic slot sliding so that mounting bracket can be removed conveniently from fixed plate, while can also conveniently paddle mounting bracket
Relatively stable is placed in fixed plate, facilitates the operation of testing staff.
The utility model is further arranged to：It is provided between the stripping rotor and the water bath described molten for fixing
Go out the fixation kit of cup, the fixation kit includes the rotating bar being rotatably connected on the water bath, is fixedly connected on rotation
Conflict piece on bar, the rim of a cup for contradicting piece and the stripping rotor contradict.
By using above-mentioned technical proposal, testing staff's rotary motion bar, rotating bar rotation, which drives, contradicts piece rotation, contradicts
Contradicted with the rim of a cup of stripping rotor after piece rotation, the position of rim of a cup limited so that stripping rotor it is relatively stable be located at water-bath
In case.
The utility model is further arranged to：The one end of the rotating bar far from the water bath is fixedly connected with rotation
Block opens up on the side of the moving block fluted.
By using above-mentioned technical proposal, the setting of groove so that contact surface between testing staff's hand and moving block compared with
It is coarse, increases the frictional force between testing staff's hand and moving block so that testing staff more can easily drives
Rotating bar rotates.
The utility model is further arranged to：Sealing cover is provided on the stripping rotor, the sealing cover includes being entrenched in
Cover board on the stripping rotor, be opened on the stripping rotor by mouth, be slidably connected on the cover board for closing institute
State the closed plate by mouth.
By using above-mentioned technical proposal, cover board can be entrenched on stripping rotor by testing staff by mouth, then drive envelope
Closing plate slides so that closed plate by mouth to being closed so that stripping rotor more seals, and reduces in stripping rotor liquid from passing through
The probability of mouth evaporation.
The utility model is further arranged to：The extraction for extracting liquid in the stripping rotor is provided on the cover board
Component, the extraction assembly include the extraction tube that grafting is arranged on the cover board, the syringe being entrenched in the extraction tube, institute
It states and is provided with fixing piece between syringe and the extraction tube.
By using above-mentioned technical proposal, testing staff is by pulling the piston on syringe so that is generated in extraction tube true
Cavity, under atmospheric pressure, the liquid in stripping rotor are flowed into from stripping rotor in syringe, facilitate testing staff to liquid
Collection.
The utility model is further arranged to：The fixing piece include the adapter sleeve being slidably connected in the extraction tube,
The chimeric block that is fixedly connected on the adapter sleeve, is opened in the fixing sleeve at the fixing sleeve being fixedly connected on the syringe
The upper and mating groove chimeric with the chimeric block.
By using above-mentioned technical proposal, the needle tubing of syringe is inserted partially into extraction tube by testing staff, is then driven
Adapter sleeve is moved towards syringe, is clamped to the contact position of extraction tube and syringe after adapter sleeve movement, while chimeric block and cooperation
Slot is chimeric so that the connection between syringe and extraction tube is more firm.
In conclusion the utility model has the advantages that：
1, by the way that detection device is arranged so that testing staff can be carried out at the same time detection in both sides, and testing staff is right
It is not easy to generate interference mutually when liquid is extracted, improves the efficiency of detection；
2, by the way that drive component is arranged, water bath and mounting bracket can move simultaneously, in the normal behaviour for not interfering agitating paddle
As while testing staff extracts the liquid in stripping rotor, facilitate the operation of testing staff.
Description of the drawings
Fig. 1 is the external structure schematic diagram of the utility model；
Fig. 2 is the attachment structure schematic diagram for embodying driving gear and drive rack；
Fig. 3 is the attachment structure schematic diagram for embodying water bath and stripping rotor；
Fig. 4 is enlarged drawing at the A of Fig. 3, embodies the connection structure by mouth and closed plate；
Fig. 5 is the attachment structure schematic diagram for embodying fixed plate and sliding groove；
Fig. 6 is the attachment structure schematic diagram for embodying extraction tube and syringe；
Fig. 7 is enlarged drawing at the B of Fig. 6, embodies the connection structure of cover board and extraction aperture；
Fig. 8 is the attachment structure schematic diagram for embodying extraction tube and syringe；
Fig. 9 is enlarged drawing at the C of Fig. 8, embodies the connection structure of adapter sleeve and chimeric block.
Reference numeral：1, rack；11, bottom plate；12, riser；13, guide rail；14, accommodating chamber；15, through hole；2, detection dress
It sets；21, water bath；211, guide rail hole；22, stripping rotor；23, mounting bracket；24, head；25, agitating paddle；26, drive component；
261, driving motor；262, gear is driven；263, drive rack；3, fixation kit；31, rotating bar；32, piece is contradicted；33, it rotates
Block；331, groove；4, sealing cover；41, cover board；411, extraction aperture；42, pass through mouth；421, holding tank；43, closed plate；5, it connects
Part；51, fixed plate；52, sliding shoe；53, sliding groove；6, extraction assembly；61, extraction tube；62, syringe；7, fixing piece；71, tight
Gu set；72, chimeric block；73, fixing sleeve；74, mating groove.
Specific implementation mode
The utility model is described further with reference to attached drawing.
As depicted in figs. 1 and 2, a kind of drug dissolution tester, including rack 1 are provided with two groups of detections dresses in rack 1
2 are set, rack 1 includes the bottom plate 11 and riser 12 of integrated setting, and bottom plate 11 is horizontally disposed, and riser 12 is vertically arranged, two groups of inspections
The both sides that device 2 is located at riser 12 are surveyed, detection device 2 includes water bath 21, stripping rotor 22, mounting bracket 23, head 24, stirs
Mix paddle 25 and drive component 26, the both sides of riser 12 are respectively fixedly connected with that there are four cylindrical guide rail 13, the axis of guide rail 13
The heart is vertical with riser 12, and water bath 21 is slidably connected at 11 upper surface of bottom plate, and integrated setting has guide rail hole on water bath 21
211, guide rail 13 is located in guide rail hole 211.Drive component 26 includes driving motor 261, drives gear 262 and drive rack 263,
Accommodating chamber 14 is offered in riser 12, driving motor 261 is located in accommodating chamber 14, and driving motor 261 is fixedly connected with bottom plate 11,
Driving gear 262 is fixedly connected on the output shaft of driving motor 261, and drive rack 263 is slidably connected at the upper table of bottom plate 11
Face, driving gear 262 are engaged with drive rack 263, through hole 15 are offered on the side wall of riser 12, drive rack 263 is separate
One end of driving gear 262 is fixedly connected across through hole 15 with water bath 21.
As shown in Figure 3 and Figure 4, several stripping rotors 22 are entrenched in water bath 21, length of the stripping rotor 22 along water bath 21
Degree direction is uniformly distributed, and fixation kit 3 is provided on water bath 21, fixation kit 3 includes rotating bar 31 and contradicts piece 32, in circle
Columnar rotating bar 31 is rotatably connected on the upper surface of water bath 21, and rotating bar 31 is circumferentially distributed along the axle center of stripping rotor 22,
The conflict piece 32 of section semicircular in shape is fixedly connected in rotating bar 31, contradicts the middle part that piece 32 is located at rotating bar 31, contradicts piece
32 is horizontally disposed, and cylindrical moving block 33 is fixedly connected in rotating bar 31, is offered on the side outer wall of moving block 33
The groove 331 of section semicircular in shape contradicts the rim of a cup after piece 32 rotates with stripping rotor 22 and contradicts.Sealing is provided on stripping rotor 22
Lid 4, sealing cover 4 include cover board 41, by mouth 42 and closed plate 43, and cover board 41 is entrenched on the rim of a cup of stripping rotor 22, are in strip
Shape is opened in by mouth 42 on cover board 41, holding tank 421 is offered on the side wall by mouth 42, section is in the cricoid closing of fan
Plate 43 is slidably connected in holding tank 421.
As shown in figure 5, slidably connecting above-mentioned mounting bracket 23 by connector 5 on water bath 21, installed on mounting bracket 23
There are several above-mentioned heads 24, head 24 to be distributed along the length direction of mounting bracket 23, agitating paddle 25 is fixedly connected on head 24,
Agitating paddle 25 is located in stripping rotor 22.Connector 5 includes fixed plate 51, sliding shoe 52 and sliding groove 53, is in the fixation of cuboid
Plate 51 is fixedly connected on the upper surface of water bath 21, and sliding groove 53 is opened in side of the fixed plate 51 far from riser 12, sliding groove
53 open up vertically, and sliding groove 53 only has one end to run through fixed plate 51, and sliding groove 53 is dovetail groove, and sliding shoe 52 is fixedly connected on peace
23 are shelved towards the side of fixed plate 51, sliding shoe 52 is slided along the length direction of sliding groove 53.
As shown in Figure 6 and Figure 7, extraction assembly 6 is provided on cover board 41, extraction assembly 6 includes extraction tube 61 and syringe 62,
Extraction aperture 411 is offered on cover board 41, extraction tube 61 is plugged in extraction aperture 411, and one end of extraction tube 61 is located at stripping rotor 22
It is interior, the other end and 62 grafting of above-mentioned syringe.As shown in Figure 8 and Figure 9, fixing piece 7 is provided between extraction tube 61 and syringe 62, Gu
It includes adapter sleeve 71, chimeric block 72, fixing sleeve 73 and mating groove 74 to determine part 7, and cylindrical adapter sleeve 71 is set in extraction tube
It is slided on 61 and along the length direction of extraction tube 61, chimeric block 72 in a rectangular parallelepiped shape is fixedly connected on adapter sleeve 71 towards syringe
62 side, cylindrical fixing sleeve 73 are fixedly connected on syringe 62, and the side of fixing sleeve 73 towards adapter sleeve 71 opens up
There are the mating groove 74 that section is rectangle, chimeric block 72 chimeric with mating groove 74.
In conclusion when testing staff needs to be detected, testing staff starts driving motor 261, driving motor 261
Driving gear 262 is driven to rotate, the driving rotation of gear 262 drives drive rack 263 to be moved along the length direction of bottom plate 11, water-bath
Case 21 moves under the drive of drive rack 263 along the direction of guide rail 13, and water bath 21 is far from riser 12, testing staff at this time
The liquid in stripping rotor 22 can be extracted by syringe 62, pushes adapter sleeve 71 far from fixing sleeve 73 after extraction, make
The fixed releasing between syringe 62 and extraction tube 61 is obtained, testing staff can remove syringe 62 from extraction tube 61, by syringe 62
Interior liquid is detected.When needing to be cleaned the taking-up of agitating paddle 25, testing staff rotates closed plate 43, then will lid
Plate 41 is removed from stripping rotor 22, is driven mounting bracket 23 to move later, so that mounting bracket 23 is moved along sliding groove 53, by mounting bracket
23 remove from riser 12, are cleaned to agitating paddle 25.
The above is only the preferred embodiment of the utility model, and the scope of protection of the utility model is not limited merely to
Above-described embodiment, technical solution belonging to the idea of the present invention belong to the scope of protection of the utility model.It should refer to
Go out, for those skilled in the art, it is without departing from the principle of the utility model it is several improvement and
Retouching, these improvements and modifications also should be regarded as the scope of protection of the utility model.
Claims (8)
1. a kind of drug dissolution tester, including rack（1）, it is characterized in that：The rack（1）On be provided with two groups of detections dress
It sets（2）, the detection device（2）Positioned at the rack（1）Both sides, the detection device（2）It is described including being slidably connected at
Rack（1）On water bath（21）, be placed on the water bath（21）Interior stripping rotor（22）, be connected to the water bath（21）
On mounting bracket（23）, be mounted on the mounting bracket（23）On head（24）, be fixedly connected on the head（24）On stir
Mix paddle（25）, the driving water bath（21）Mobile drive component（26）, the agitating paddle（25）Positioned at the stripping rotor
（22）It is interior.
2. a kind of drug dissolution tester according to claim 1, it is characterized in that：The driving component（26）Including peace
Mounted in the rack（1）On driving motor（261）, be fixedly connected on the driving motor（261）Sliding tooth on output shaft
Wheel（262）, be slidably connected at the rack（1）On drive rack（263）, the drive rack（263）With the sliding tooth
Wheel（262）Engagement.
3. a kind of drug dissolution tester according to claim 2, it is characterized in that：The mounting bracket（23）Pass through connection
Part（5）With the water bath（21）Connection, the connector（5）Including being fixedly connected on the water bath（21）On fixed plate
（51）, be fixedly connected on the mounting bracket（23）On sliding shoe（52）, be opened in the fixed plate（51）On sliding groove
（53）, the sliding shoe（52）Along the sliding groove（53）Length direction sliding.
4. a kind of drug dissolution tester according to claim 1, it is characterized in that：The stripping rotor（22）With the water
Bath cabinet（21）Between be provided with for fixing the stripping rotor（22）Fixation kit（3）, the fixation kit（3）Including rotation
It is connected to the water bath（21）On rotating bar（31）, be fixedly connected on rotating bar（31）On conflict piece（32）, described to support
Contact（32）With the stripping rotor（22）Rim of a cup contradict.
5. a kind of drug dissolution tester according to claim 4, it is characterized in that：The rotating bar（31）Far from described
Water bath（21）One end be fixedly connected with moving block（33）, the moving block（33）Side on open up it is fluted（331）.
6. a kind of drug dissolution tester according to claim 1, it is characterized in that：The stripping rotor（22）On be provided with
Sealing cover（4）, the sealing cover（4）Including being entrenched in the stripping rotor（22）On cover board（41）, be opened in the stripping rotor
（22）On pass through mouth（42）, be slidably connected at the cover board（41）On for closing described pass through mouth（42）Closed plate
（43）.
7. a kind of drug dissolution tester according to claim 6, it is characterized in that：The cover board（41）Upper setting is useful
In the extraction stripping rotor（22）The extraction assembly of interior liquid（6）, the extraction assembly（6）It is arranged in the cover board including grafting
（41）On extraction tube（61）, be entrenched in the extraction tube（61）On syringe（62）, the syringe（62）With the extraction tube
（61）Between be provided with fixing piece（7）.
8. a kind of drug dissolution tester according to claim 7, it is characterized in that：The fixing piece（7）Including sliding
It is connected to the extraction tube（61）On adapter sleeve（71）, be fixedly connected on the adapter sleeve（71）On chimeric block（72）, it is solid
Surely it is connected to the syringe（62）On fixing sleeve（73）, be opened in the fixing sleeve（73）It is upper and with the chimeric block（72）It is embedding
The mating groove of conjunction（74）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721765719.XU CN207730744U (en) | 2017-12-15 | 2017-12-15 | A kind of drug dissolution tester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721765719.XU CN207730744U (en) | 2017-12-15 | 2017-12-15 | A kind of drug dissolution tester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207730744U true CN207730744U (en) | 2018-08-14 |
Family
ID=63098671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721765719.XU Active CN207730744U (en) | 2017-12-15 | 2017-12-15 | A kind of drug dissolution tester |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207730744U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109374845A (en) * | 2018-11-05 | 2019-02-22 | 禄根仪器(镇江)有限公司 | A kind of efficient medicament dissolution instrument |
| CN109464932A (en) * | 2018-11-05 | 2019-03-15 | 禄根仪器(镇江)有限公司 | A kind of digestion instrument dedicated multizone synchronous variable-speed mechanism |
| CN114252526A (en) * | 2021-12-20 | 2022-03-29 | 辰欣药业股份有限公司 | Valsartan and hydrochlorothiazide tablet dissolution device and dissolution curve detection method |
| CN116660484A (en) * | 2023-07-26 | 2023-08-29 | 广州誉东健康制药有限公司 | Simvastatin tablet dissolution rate measurement equipment |
-
2017
- 2017-12-15 CN CN201721765719.XU patent/CN207730744U/en active Active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109374845A (en) * | 2018-11-05 | 2019-02-22 | 禄根仪器(镇江)有限公司 | A kind of efficient medicament dissolution instrument |
| CN109464932A (en) * | 2018-11-05 | 2019-03-15 | 禄根仪器(镇江)有限公司 | A kind of digestion instrument dedicated multizone synchronous variable-speed mechanism |
| CN109374845B (en) * | 2018-11-05 | 2024-03-29 | 禄根仪器(镇江)有限公司 | Efficient medicine dissolves out appearance |
| CN114252526A (en) * | 2021-12-20 | 2022-03-29 | 辰欣药业股份有限公司 | Valsartan and hydrochlorothiazide tablet dissolution device and dissolution curve detection method |
| CN114252526B (en) * | 2021-12-20 | 2022-10-11 | 辰欣药业股份有限公司 | Valsartan and hydrochlorothiazide tablet dissolution device and dissolution curve detection method |
| CN116660484A (en) * | 2023-07-26 | 2023-08-29 | 广州誉东健康制药有限公司 | Simvastatin tablet dissolution rate measurement equipment |
| CN116660484B (en) * | 2023-07-26 | 2023-09-22 | 广州誉东健康制药有限公司 | Simvastatin tablet dissolution rate measurement equipment |
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