CN207703867U - A kind of detection device with hemostix - Google Patents
A kind of detection device with hemostix Download PDFInfo
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- CN207703867U CN207703867U CN201721188212.2U CN201721188212U CN207703867U CN 207703867 U CN207703867 U CN 207703867U CN 201721188212 U CN201721188212 U CN 201721188212U CN 207703867 U CN207703867 U CN 207703867U
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- hemostix
- detection device
- sample
- solution storage
- detection
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Abstract
The utility model provides a kind of detection device with hemostix, it is characterized in that, the device includes hemostix, the hemostix is inserted into inserting in the hole for detection device, wherein, the hemostix includes a projecting block, which is located on the inner wall in the cavity of detection device and close to the test chamber.Hemostix is allowed to be fixed on detection means, to form integrated apparatus, convenience in transport and use in this way.
Description
Technical field
The utility model is related to a kind of device and method for detecting the analyte in fluid sample particularly to belong to
The device and method of analyte particularly belong to a kind of detection device with hemostix in detection blood sample.
Background technology
Following background technology is used to help reader and understands the utility model, and is not construed as the prior art.
Blood is always the common sample of warp of detection field, because containing many Biological indicators or being analyzed in blood
Substance.In the fields POCT, if necessary to carry out the detection of analyte to blood, it is typically necessary the receipts for carrying out blood
Collection, such as with the capillary on blood-taking needle broken skin skin, the acquisition of blood sample is carried out with blood sampling tool, then carries out blood
The analysis of sample.Generally when individual carries out blood sample detection, blood taking needle is needed, take a blood sample tool and detection device,
It usually can also carry the solution reagent of processing blood.These general apparatus are all packed in together, not only bad for packaging, and
And when use, the trouble used, or the damage to human body can be caused.
This is improved with regard to the device in need to traditional detection blood sample, with the defect more than overcoming, allows use
Person is more convenient and convenient.
Utility model content
In order to solve the problems in the existing technology, the utility model provides a kind of detection fluid sample, and it is blood that spy is standby
Liquid, the device of middle analyte, the device include：Solution storage, for puncturing the puncturing elements of solution storage.It punctures
The puncturing of element allows solution storage release solution.
On the one hand, the utility model provides a kind of detection device with hemostix, which is characterized in that the device includes adopting
Blood device, the hemostix are inserted into inserting in the hole for detection device, wherein the hemostix includes a projecting block, should
Projecting block is located on the inner wall in the cavity of detection device and close to the test chamber.Preferably, which is characterized in that described
Hemostix includes blood sampling head.Preferably, which is characterized in that the hemostix is " L " shape.Preferably, which is characterized in that institute
The projecting block stated be located at " L " shape it is long-armed on.Preferably, which is characterized in that the insertion Kong Kongwei rectangles, hemostix
For tubular structure, rectangular height is corresponding with the diameter of the tubular structure of hemostix.Preferably, which is characterized in that described
Projecting block is rectangular parallelepiped structure, and the tubular structure of hemostix is in approximately the same plane.Preferably, which is characterized in that described
" L " shape hemostix it is long-armed be located at detection device in, galianconism is located at outside detection device.Preferably, which is characterized in that institute
The detection device stated further includes solution storage device, and in solution storage device upper including lockhole, the blood sampling head is located in lockhole.
A kind of detection device with hemostix, which is characterized in that the device includes hemostix, and the hemostix is inserted
Enter inserting in the hole to detection device, wherein the detection device further includes solution storage device, in solution storage device in Shang Bao
Lockhole is included, the hemostix includes blood sampling head, and the blood sampling head is located in lockhole, to which fixed solution reservoir is detecting
Position on device.Preferably, which is characterized in that the hemostix includes a projecting block, and the projecting block is cuboid
Structure, and the tubular structure of hemostix are in approximately the same plane.
In some preferred modes, which further includes hemostix for collecting blood sample and/or is used for
Penetrating tissue punctures device (needle or sharp structure).In some preferred modes, the hemostix is tubular structure.
Preferably, hemostix includes blood sampling head, and blood sample is collected using the blood sampling head.Preferably, the hemostix " L " shape
Shape.Preferably, the hemostix further includes fixed block.Preferably, include on detection means the hole for allowing hemostix to be inserted into.It is excellent
Choosing, which designs in this way, and hole can allow the tubular structure of hemostix to be inserted into, it can however not allowing fixation
Block is consistent with the direction that tubular structure is inserted into, but needs to rotate hemostix, to allow fixed block to be inserted into the hole.Phase
Instead, it when needing to take out hemostix, needs to rotate hemostix according to the opposite direction of insertion, to take from the hole
Go out.In this way, can be very good that hemostix is allowed to be fixed in detection device, hemostix will not be allowed from detection because of long-distance transportation
Device is backing out.In some preferred modes, the hole in the detection device is rectangle, and the fixed block of hemostix
For rectangle, but fixed block is perpendicular to the tubular structure of hemostix.In some preferred modes, the rectangular hole
Height be adapted with the tubular structure of hemostix, can allow or just the tubular structure of hemostix can be allowed to pass through, and cannot
Fixed block is allowed to pass through.The height in rectangular hole is more than the height of fixed block.It is corresponding, the length side in the rectangular hole
To the length direction more than fixed block, in this way when being inserted into hemostix into the hole, need to rotate hemostix, to
Fixed block is allowed to be entered in hole by the hole.It can allow hemostix is locked to be located in detection device in this way.
In some preferred modes, hemostix by being inserted into the hole of detection device, and head of taking a blood sample be inserted into it is molten
In the keyhole of liquid storage, to, which can protect the head of hemostix not to be destroyed, in addition, as described below, it can also
Fixed solution storage is played in first fixed position without being moved relative to detection device.Because movement can allow solution to store
What device touched puncturing elements punctures head, so as to cause the leakage of solution.
In some preferred modes, which further includes testing element, and blood sample can be detected by testing element
The presence of middle analyte or quantity.
On the other hand, the utility model provides a kind of detection device with solution storage device, which is characterized in that the device
Including solution storage device, the solution storage device has one and the second position on detection means, and solution storage device can
It is moved to the second position from first position.Preferably, which is characterized in that the solution storage device includes solution cavity, the chamber
The diaphragm seal that body is easy to puncture.Preferably, which is characterized in that solution cavity includes solution reagent.Preferably, feature
It is, it is latched position that solution storage device, which is located at first position,.Preferably, which is characterized in that the latched position is by adopt
Blood device is locked, wherein in solution storage device upper including lockhole, the blood sampling head is located in lockhole.Preferably, feature
It is, the solution storage device includes slip lid, has a gap between slip lid and solution cavity.Preferably, which is characterized in that
The solution storage device includes sliding rail, includes the income area for accommodating solution storage device in the detection device,
Income is provided with sliding slot corresponding with sliding rail in area.Preferably, which is characterized in that in the detection device include for holding
Receive the income area of solution storage device, the solution storage device of receiving has first seat and second in taking in area
It sets.
In some specific embodiments, solution storage is actively clamped on detection means and in detection device
In have first position and the second position.Preferably, solution storage can be moved to the second position from first position.It is preferred that
, solution storage is moved along the y direction of detection device.Preferably, solution storage is not punctured member in first position
Part punctures.Preferably, solution storage is punctured element in the second position and punctures.
In some preferred modes, when solution storage is located at first position, by a retaining element fix to
It cannot move.Preferably, the retaining element is hemostix.Preferably, the hemostix is fixed in a manner of bolt
Solution storage.Preferably, it is acicular structure to have keyhole, hemostix on solution storage, and hemostix passes through detection device
On hole and be inserted into the keyhole of solution storage.
In some preferred modes, the detection device includes upper plate and lower plate, and the testing element is located at upper plate
Between lower plate.Preferred testing element includes sample application zone, reagent test area.It is stored up close to solution the sample application zone
Hide device.Preferably, the solution storage is located on upper plate, wherein upper plate includes the space for accommodating solution storage.The sky
Between and solution storage be adapted.
In some preferred schemes, the hole that hemostix passes through is allowed to be located on upper plate in the detection device.Another party
Face, the utility model provide a kind of detection device with puncturing elements, which is characterized in that the device includes that solution punctures member
Part, the puncturing elements include puncture head and with the pipeline that punctures head and connect.Preferably, which is characterized in that the inspection
Survey device further include solution storage device and testing element, wherein the puncturing elements be located at receive solution storage device with test
Between the sample applied area of element.Preferably, which is characterized in that the pipeline has both ends open, the one end open of pipeline
Close to the sample applied area of testing element, another end opening is close to solution storage device.Preferably, which is characterized in that the inspection
It includes sample application well to survey device, this is that application well is located in sample applying zone, wherein the sample of the close testing element
Upstream of the opening in sample application well of this applied area.Preferably, which is characterized in that the puncturing elements further include fixing
Block is fixed on by the fixed block in detection device.Preferably, which is characterized in that the detection device include upper plate and
Lower plate, the testing element are located in the slot of lower plate, and the puncturing elements are located on upper plate.Preferably, which is characterized in that
The puncturing elements are located in detection device.
In some preferred modes, the detection device further includes lancing device, which can puncture molten
Liquid storage.In some preferred modes, solution storage includes a cavity containing opening, which is easy to be pierced
Broken diaphragm seal.Puncturing elements puncture the film, to the solution in release solution storage.
In some preferred modes, the puncturing elements be located at solution storage and test-strips sample application zone it
Between, and keep liquid to flow shape body by puncturing elements and solution storage between sample application zone.
Preferably, puncturing elements include puncturing head, this, which punctures head, can puncture the film of solution storage.Preferably, it pierces
Include that one or more sharp punctures device on broken head.Preferably, puncturing elements include a channel, which can allow brokenly molten
The solution of liquid storage is flowed to by the channel on sample application zone.In some preferred modes, the passage end
Opening, which is located at, to be punctured in device, the opening of the other end in channel and sample application zone fluid together with.In some preferred modes, thorn
Broken element can puncture the film of solution storage, be entered in the solution storage chamber of solution storage to puncture head.One
In a little preferred modes, puncturing elements are fixed in detection device, and solution storage movable peace opposite with detection device
It is fitted together.
On the other hand, the utility model provides a kind of method detecting analyte in blood sample, and this method includes：
Detection device is provided, which includes testing element, and solution storage, can puncture storage punctures member
Part, wherein solution storage have the first fixed position and the second position in detection device；
Solution storage is allowed to be moved to the second position from first position；In the process of moving, to allow puncturing elements to puncture molten
Liquid storage, to the solution in release solution storage.Preferably,
The method of analyte, this method include in a kind of detection sample：A kind of detection device is provided, the detection device
Including：Solution storage device, hemostix and puncturing elements, wherein the solution storage device has first in detection device
It sets and the second position, solution storage device can be moved to the second position from first position.Solution storage device is allowed to be moved from first position
It moves to the second position, in moving process, puncturing elements is allowed to puncture solution storage device, to release solution.Preferably, the detection
Device includes testing element, and the solution released is allowed to be flowed into the sample applied area of testing element by the pipeline of puncturing elements
On.
On the other hand, the utility model provides a kind of device detecting analyte in sample, including：Solution storage
Device, hemostix and puncturing elements, wherein the solution storage device has first position and the second position in detection device,
Solution storage device can be moved to the second position from first position, wherein when solution storage device is located at the second position, thorn
Broken element punctures solution storage device to release solution.Preferably, which is characterized in that it is lock that solution storage device, which is located at first position,
Positioning is set, and the latched position is locked by hemostix, wherein in solution storage device upper including lockhole, the blood sampling
Head is located in lockhole.Preferably, which is characterized in that the detection device includes being inserted into hole, and the hemostix is inserted into
This inserts in the hole.Preferably, which is characterized in that the detection device further includes testing element, and the puncturing elements include
Puncture head and with the pipeline that punctures head and connect, the pipeline has both ends open, and the one end open of pipeline is close to test member
The sample applied area of part, another end opening is close to solution storage device.Preferably, which is characterized in that the puncturing elements are located at
Between solution storage device and test sample sample areas.Preferably, which is characterized in that the puncturing elements further include fixing
Block is fixed on by the fixed block in detection device.Preferably, which is characterized in that when solution storage device is located at the second position
When, the head that punctures of puncturing elements enters in the solution cavity of solution storage device.Preferably, which is characterized in that work as solution
When reservoir is located at first position, puncturing elements puncture head and cannot be contacted with the solution cavity of solution storage device.
Advantageous effect
Using the device of the utility model, blood sampling, buffer solution, detection device is allowed to be structure as a whole, can be completed with a step
The collection and detection of blood sample.
Description of the drawings
Fig. 1 is the exploded perspective structural schematic diagram of the detection device in a specific implementation mode of the utility model.
Fig. 2 is the three-dimensional structure diagram (not containing sealing film) of the solution storage of the utility model one embodiment.
Fig. 3 is the sectional view of the solution storage in Fig. 2.
Fig. 4 is the three-dimensional structure diagram (including sealing film) of the solution storage of the utility model one embodiment.
Fig. 5 is the dimensional structure diagram of the puncturing elements of the utility model one embodiment.
Fig. 6 is the sectional view of puncturing elements shown in fig. 5.
Fig. 7 is that the stereochemical structure of the lancing device for puncturing device containing penetrating tissue of the utility model one embodiment is shown
It is intended to.
Fig. 8 is that the combination dimensional structure diagram of the detection device in the utility model one embodiment (does not include blood sampling
Device).
Fig. 9 is the dimensional structure diagram of the hemostix in the utility model one embodiment.
Figure 10 be the utility model one embodiment in detection device combination dimensional structure diagram (including blood sampling
Device).
Figure 11 is the partial structurtes enlarged diagram of the device shown by Figure 10.
Figure 12 is the present invention looks up structural representation of the upper plate of the detection device in the utility model one embodiment.
Figure 13 is the structural schematic diagram of the lower plate of the detection device in the utility model one embodiment.
Figure 14 is combination dimensional structure diagram (including the hemostix of the detection device in the utility model one embodiment
Positioned at fixed position).
Figure 15 is the partial structurtes enlarged diagram of the detection device shown by Figure 14.
Figure 16 is the combination dimensional structure diagram of the detection device in the utility model one embodiment, wherein solution
Storage is moved to the second position.
Figure 17 is the cross-sectional view of the detection device in the utility model one embodiment, wherein.Solution is stored
Device is located at the first status.
Figure 18 is the cross-sectional view of the detection device of Figure 16.
Specific implementation mode
Below to the utility model is related to structure or these used technical terms be described further.These are said
Bright is only how to be realized in such a way that way of example illustrates the utility model, can not be to the utility model
Constitute any limitation.
Detection
Detection indicates chemical examination or tests a kind of substance or material whether there is, for example, but it is not limited to this, chemical substance,
Organic compound, inorganic compound, metabolism product, drug or drug metabolite, organic organization or organic organization generation
Thank object, nucleic acid, protein or polymer.In addition, detection indicates test substances or the quantity of material.Furtherly, table is gone back in chemical examination
Show immune detection, chemical detection, enzyme detection etc..
Testing element
A variety of testing elements 60 can be in combination application to the utility model.Testing element includes test-strips, analysis test
Item can there are many forms, for example, by using immune or test chemical form, for detecting the analyte in sample, such as poison
Product or the correlative metabolites for indicating physical condition.In some forms, test-strips are with sample application zone, reagent area and testing result
The water-absorbing material in area.Sample is added to sample application zone, and reagent area is flowed into using capillarity.In reagent area, sample dissolving examination
Agent and it is mixed can be used for detect analyte (if there are analytes in sample).The sample for carrying reagent at this time continues
It flow to test results zone.Other reagent is fixed on test results zone.These are fixed on the reagent of detection zone and are divided
Analysis object (if present) is reacted and is combined with the first reagent of reagent area.In noncompetitive test format, such as
There are analytes just will produce signal in fruit sample, if analyte is not present, does not generate signal.Shape is detected in competition
In formula, signal is generated if analyte is not present in sample, signal is not generated if if there is analyte.This practicality is new
Type is suitable for various analytical forms.
When the test element is a test strip, it can be made of water suction or unwetted property material, and test-strips can be with
Using multiple material, it to be used for the transmission of liquid.A kind of material of test-strips can be superimposed upon on another test strip material, example
Such as, filter paper overlaid is on nitrocellulose.Alternatively, a region at least containing a kind of material in test-strips is located at another kind at least
After a kind of region of different materials.In this case, liquid is circulation between each region, can phase between them
It is mutually superimposed or is not superimposed.Material in test-strips can be fixed on such as support of plastics liner or hard surface,
It can holding force to reinforce test-strips.
In the embodiment that some detected materials are detected by signal generation system (as at least one enzyme be detected
Specific reaction occurs for object), at least one substance for generating signal can be attracted to the analyte detection zone of test-strips, just
It is specifically adsorbed on the material of test-strips as described above the same.Additionally, there are in the sample application zone, reagent area, quilt of test-strips
Analyte detection zone, or generation signal throughout entire test-strips substance can pre-process in advance at one of test-strips or
On multiple materials.It can be by the way that the substance solution for generating signal to be added to the surface of application area or by one or more of test-strips
Material is immersed in signal solutions and realizes.After test-strips add signal solutions or impregnate in the solution, test-strips are dried
It is dry.In addition, above method is present in the sample application zone, reagent area, analyte detection zone of test-strips, or throughout entire test
The substance of the generation signal of item can be pre-processed in advance on one or more materials of test-strips.Additionally, there are add in test-strips
The semiochemicals of sample area, reagent area or detection zone can be added to one or more tables of test strip material as labelled reagent
Face.
Each region of test-strips can be arranged as follows：Sample application zone 601, at least one reagent area, at least one test results zone
602, at least one control zone, at least one detection of adulterations area and liquid absorption area 603.If detection zone includes a control
Area, preferably control zone are located at after the analyte detection zone of test results zone.All these areas or combinations thereof can containing
In a kind of single test strips of material.In addition, these areas are made from a variety of materials, and one is connected to by the direction that liquid transmits
It rises.For example, different zones can directly or indirectly carry out liquid transmission.In the present example, different areas can be passed along liquid
The direction end passed is connected with end, or is overlapped mutually along liquid direction of transfer, or is connected by other materials, such as connects
Connect dielectric material (preferably water-absorbing material such as filter paper, glass fibre or nitrocellulose).When with connecting material, material is connected
Material can make material, the end comprising each region and the joining distal ends but liquid of the end comprising each region and joining distal ends not circulate
Material or comprising the material that each region overlapped (such as, but not limited to from the beginning to the end be overlapped) but liquid do not circulate, formed
Liquid communication.
If test-strips contain detection of adulterations control zone, which can be placed on before or after result detection zone.Work as knot
Control zone is contained in fruit judgement area, and adulterated control zone is preferably positioned at before control zone, may not be such situation.This practicality
Novel one embodiment, test-strips are the control test-strips for judging and/or controlling for adulteration analyte, and adulterated control zone can be with
Before or after control zone, it is preferably placed at before control zone.
In specific embodiment of the present utility model, testing element or test-strips can be located at testing element carrier
In, carrier can be the card slot such as the lower plate 102 in Fig. 1.Preferably, it is located at testing element carrier, such as the slot of lower plate 102
In.
Sample
The sample that can be detected with the detection device of the utility model includes biofluid (such as casing fluids or clinic
Sample).Either fluid sample can derive from the sample of solid-state or semisolid, including excreta, biological tissue to liquid sample
And food samples.The sample of solid-state or semisolid can be converted to liquid sample using any method appropriate, such as mix,
It smashs to pieces, macerate, being incubated, dissolving or (such as water, phosphate solution or other buffer solutions) utilize enzymolysis in a suitable solution
Act on digestion of solid sample." biological sample " includes deriving from animal, plant and food samples, such as including deriving from people or dynamic
The urine of object, saliva, blood and its ingredient, spinal fluid, vaginal fluid, sperm, excrement, sweat, secretion, tissue, organ, tumor,
The culture of tissue and organ, cell culture and medium.Preferred biological sample is urine.Food samples include the object of food processing
Matter, final products, meat, cheese, wine, milk and reference water.Plant sample includes being derived from any plant, plant tissue, and plant is thin
Born of the same parents' culture and medium." environmental samples " are from environment (for example, coming from lake or the liquid sample of other water bodys, sewage
Sample, soil property sample, underground water, seawater and waste liquid sample).Environmental samples may also include sewage or other waste water.Utilize this
Utility model and suitable detecting element, can detect any analyte.It is detected in blood preferably by the utility model
Analyte.
Analyte
Can include some haptens substances, these haptens packets with the example of the analyte involved in the utility model
Include drugs (such as drug abuse)." drug abuse " (DOA) refers to that the work of paralysis nerve (is usually played in non-medical destination using drug
With).Abusing these drugs can cause body ＆ mind to be damaged, and generate dependence, addicted and/or dead.Drug is indiscriminate
Example includes cocaine；Amphetamine AMP is (for example, black beauty, white amphetamine tablet, dextroamphetamine, dextrorotation
Amphetamine tablet, Beans)；Crystal methamphetamine MET (crank, meth, crystal, speed)；Barbiturate
BAR (such as Valium, Roche Pharmaceuticals, Nutley, New Jersey)；Sedative (adjuvant of sleeping
Product)；Lysergic acid diethylamide (LSD)；Inhibitor (downers, goofballs, barbs, blue devils, yellow
Jackets, methaqualone)；The anti-antidepressant of tricyclic antidepressants (TCA, i.e. imipramine, amitriptyline and doxepin)；Two methylenedioxy groups
Methylaniline MDMA；Phencyclidine (PCP)；Tetrahydrocannabinol (THC, pot, dope, hash, weed, etc..)；Opiate
(i.e. morphine MOP or opium, cocaine COC, heroin, hydroxyl dihydrocodeinone)；Anxiolytic and hypnotic sedative agent resist
Anxiety medicine is that one kind is mainly used for anxiety reduction, anxiety, fear, sets the mind at rest, has the drug of hypnosis sedation, including benzene concurrently
Diazepine BZO (benzodiazepines), atypia BZ classes, fusion phenodiazine NB23C classes, benzene nitrogen Zhuo class, BZ receptors are matched
Body class, open loop BZ classes, diphenylmethane derivatives, piperazine carboxylic acid salt, piperidine carboxylic acid salt, Kui oxazoline ketone, thiazine and thiazole
Derivative, other heterocyclics, imidazole type calmness/anodyne (such as hydroxyl dihydrocodeinone OXY, methadone MTD), propylene glycol derive
Object-carbamates, aliphatic compound, anthracene derivative etc..It can be used for examining using the detection device of the utility model
The detection for belonging to medical usage but being easy overdose is surveyed, such as tricyclic antidepressant (imipramine or the like) and acetyl ammonia
Base phenol etc..These drugs can resolve into different small-molecule substances after being absorbed by the body, these small-molecule substances be present in blood,
In the body fluid such as urine, saliva, sweat or part body fluid there are above-mentioned small-molecule substances.
The analyte detected with the utility model includes but not limited to creatinine, bilirubin, nitrite, albumen
(non-specificity), hormone (for example, human chorionic promotes sex hormone, luteinizing hormone, follicular stimulating hormone etc.), blood, white blood cell,
Sugar, heavy metal or toxin, bacterial components (albumen or glucide as being directed to specific bacterial, such as such as colon bacillus 0157：
H7, staphylococcus, salmonella, fusobacterium, Campylobacter, L.monocytogenes, vibrio or cactus bacillus) and urine
In sample with the relevant substance of physiological characteristic, such as pH and proportion.Other any Clinical Urinary chemical analyses are all examined using lateral flow
Survey form cooperation utility model device is detected.
Detection device
The detection device of the utility model includes testing element 60, and testing element can be used for detecting sample, such as blood
Analyte whether there is in sample.In some modes, detection device includes upper plate 101 and lower plate 102, and upper plate 101 wraps
The income area 115 of a receiving solution storage device is included, while further including that well 104 and testing result read hole 103, lower plate
Including slot structure, testing element is located in slot structure, in Figure 13.In some preferred modes, detection device includes one
Lockhole 106 for being inserted into hemostix 50, cover lock pore structure can allow hemostix to be fixed in detection device, while can protect
Shield collector is not damaged, while hemostix can play fixed solution reservoir in the position for taking in area 115 of detection device.
In some preferred modes, which further includes that firmly penetrating tissue bloodletting punctures device 20, this is punctured
Device includes a sharp needle, blood vessel can be punctured with penetrating tissue, to discharge blood sample (such as Fig. 1, Tu14Suo in tissue
Show).In a preferred mode, one end that device 20 is located at detection device is punctured, is partly located in detection device, part is exposed
Go out, when operation in this way, the position of tissue, such as finger tip be directly directed at one end of detection device, carries out puncturing behavior,
Once punctured, first 502 are taken to carry out taking blood sample with hemostix 50 immediately, for example, simultaneously, can be filled from detection
Middle taking-up is set to puncture device 20 and abandoned.Alternatively, when needing to puncture tissue, can be taken out from detection device
It punctures device 20 and carries out tissue and puncture to discharge blood and come out, then directly abandon.Can specifically elaborate below result and
Effect.
Solution storage device
In some preferred modes, the detection device of the utility model includes one and accommodates solution storage device 30, is examining
It includes an income area 115 for accommodating solution storage device 30 to survey device.In some preferred modes, solution storage device
30 have first position and the second position in detection device, can be moved to the second position from first position.Preferred
Mode in, first position be locking position.In some preferred modes, the solution storage device 30 be one substantially
The shape of square, tool is there are six a cavity in face besieged city, and for the cavity 303 tool there are one opening 308, the opening 308 is thin
Film 31 seals.In contrast, the film 31 of sealed opening is to be easy the film punctured, such as aluminium foil film, plastic film, using sharp
The form of light or thermoplastic envelope is sealed.Before sealing, solution is full of or poured in cavity, which is used for handling sample
This solution, such as blood sample, solution can be the solution for changing sample PH, can also be to remove impurity in sample or do
Disturb ingredient.Solution can contain any suitable ingredient or suitable chemical substance, and the effect of these solution can be with one kind
Effect, can also be play the role of it is a variety of.
The solution storage device 30 further includes sliding rail 304 and slip lid 301, and the effect of sliding rail is exactly the receipts with detection device
Enter the corresponding sliding slot cooperation in area, allows reservoir 30 that can be free to enter income area, and due to the effect of sliding rail, can prevent
Reservoir 30 moves left and right in income area 115.There are one gap 305, the gaps for tool between the slip lid and cavity of reservoir 30
Between slip lid 301 and a face of cavity, the gap be used for it is correspondings with the income position in area 115, to be conducive to allow storage
Device 30 is moved to the second position from first position.
In some preferred modes, which includes a lockhole 302, changes lockhole 302 and is located at cavity
On one face, and the attachment of the insertion sky 106 positioned at detection device, effect is exactly to allow the blood sampling head 502 of hemostix to be located at
In lockhole, there are several effects, one is that protection blood sampling head 502 is not damaged, in addition, since blood sampling head 502 is located at lockhole 302
In, reservoir 30 can be prevented to be moved to the second position from first position, reservoir 30 is allowed to be in the position of locking in first position
It sets.Be in the locked position optionally to be moved to the second position from first position, after only unlocking, such as take out hemostix
Afterwards, reservoir 30 can just be allowed freely to be moved all the second position (such as Figure 10, Figure 11) from first position.
Hemostix
In some preferred modes, detection device further includes hemostix 50, and wherein hemostix is located in detection.At some
In mode, hemostix is inserted into the insertion sky 106 of detection device, it is allowed to be not easy to fall from detection device.One
In a preferred mode, hemostix 50 be tubular structure, hemostix include take first 502, for blood sample acquisition and
Blood sample is applied on the sample applied area 601 of testing element after acquisition, application can be by the upper plate of detection device
Sample aperture apply (such as Figure 16).In other mode, hemostix is substantially " L " shape (Fig. 9), " L " shape it is long-armed on
Including a projecting block 504, it is preferred that the protrusion generally rectangle soon has the two sides in 4 long faces 505 and square
It surrounds.
It is corresponding, include being inserted into hole 106 on detection means, for allowing hemostix to be inserted into detection device.Such as scheme
Shown in 11.It is inserted into the opening of 106 general rectangulars in hole, when being inserted into hemostix 50, the height for being inserted into hole is more than blood sampling
The diameter of device, meanwhile, the height of the projecting block of hemostix 50 is suitable with the diameter of hemostix, but the height of projecting block be more than adopt
The diameter of blood device.Or, it is preferred that the length direction of projecting block and the tubular structure of hemostix are generally in approximately the same plane.
In this way, when being inserted into collector, the insertion that makes the projecting block 504 of hemostix 50 parallel with entrance 106 enter (such as Figure 11 and
12) projecting block 505 of, this when, hemostix are parallel with the length direction of detection device (Figure 11), one end of hemostix 50
(without head is taken) is also parallel with the length direction of detection device.This when, blood sampling head 502 are located at container storage 30
In lockhole 302, play the role of fixed solution reservoir 30.
Hemostix be inserted into be inserted into hole 106 after, counterclockwise rotate, allow hemostix 50 one end (without head is taken) with inspection
The length direction for surveying device is vertical, with rotation, is located at inner wall of the projecting block 504 close to detection device upper plate of collector 50
On 130, (such as Figure 15), while rotating, the blood sampling head 502 of hemostix is also while in the lockhole 302 of solution storage device 30
Rotation.Projecting block is really the rotation in a cavity 120 of detection device, when grade close to inner wall 130 of cavity 120,
Collector stops rotating, in this way, can be to allowing collector to be fixed in detection device using projecting block 504, it is not easy to fall.Separately
Outside, it is inserted into lockhole 302, allows solution storage device 30 to lock or be fixed on first position, in this way, second would not be moved to
It sets.
When needing taking-up collector to carry out taking sample, hemostix is rotated according to negative direction described above, is taken
Go out hemostix 50 for taking blood sample, take it is after-applied in sample applying zone 601, while taking out hemostix,
It makes solution storage device 30 in the unlocked state, solution storage device 30 can be allowed to be moved to the second position from first position, to allow
Puncturing elements puncture the film of the solution cavity of sealing solution storage device 30, apply to the sample of release solution to testing element
On region.After hemostix 50 applies sample, can directly it abandon.
Puncturing elements
In some preferred modes, the utility model further includes puncturing elements 40, and puncturing elements include puncturing first 409,
It includes some sharp structures 404 to puncture on head, can be in direct contact film.Meanwhile first 409 are punctured with slightly big body
Product, the volume are less than the volume of the cavity 303 on solution storage device 30.In this way, puncturing after head can puncture film, cavity is entered
In, there is certain volume due to puncturing head, after entering solution cavity 303, the liquid of solution cavity 303 can be forced to flow out
Come.In some preferred modes, one pipeline 405 of first 409 connection is punctured, pipeline has hollow channel 407, pipeline one
End, which connects, punctures head, the sample applying zone 601 of other end connecting test element, in this way, in the cavity on solution storage device 30
Solution be flowed into sample applying zone 601 by the channel 407 of pipeline 405.There are two opening, one end opens for pipeline tool
406 and sample applying zone it is close, the opening 403 of the other end, which passes through, punctures head or among sharpened configuration.Puncture head into
Enter into solution cavity 303, solution is flowed into sample applying zone (Fig. 5 and Fig. 6) by channel.
In a preferred mode, puncturing elements include a fixing piece 402, the fixing piece and the machine in detection device
Structure coordinates, and punctures head to allow and is fixed in detection device.Specifically, fixing piece is the structure of a rectangular plate, puncture
The pipeline of element passes through the plate, harden structure to be connected in detection device (such as Figure 12).Preferably, puncturing elements are arranged on upper plate
On 101.In some preferred modes, puncturing elements are so-called between sample applying zone 601 and solution storage device 30
" between " it is not to be individually separated, it can also be respectively overlapped, i.e. one end 406 of the pipeline of puncturing elements is applied positioned at sample
The top for adding region punctures head and enters in solution cavity 303 when solution storage device 30 is moved to the second position.
In some preferred modes, the opening 406 of the puncturing elements pipeline other end be located in sample applying zone 601 but
It is the upstream (such as Figure 12) in sample application well 104, allows solution to be flowed into applying zone 601 by opening 406 in this way, so
Afterwards using the position of application well 104, can play the role of handling sample in this way.
Puncture device
In some preferred modes, which includes puncturing device 20, is arranged on the another of solution storage device 30
It holds (Fig. 1 and Figure 14).It is commonly to puncture mechanism to puncture device, and it includes a sharp needle generally to puncture device, is used for penetrating tissue
The function of bloodletting.These structures are all common structure, traditional structure.
Detection method
Below in conjunction with the accompanying drawings come illustrate how carry out fluid sample in analyte detection.
Prepare detection device, such as detection device shown in Figure 16 or Figure 14, including punctures device, hemostix and solution storage
Element 40 is broken in storage 30, and the side of setting plate on detection means.Hemostix is inserted into insertion in the way of Figure 14 and 15
In hole and lockhole (such as Figure 17).This when, solution storage device 30 was in the first position of locking.
When needing detection, first with device 20 is punctured come penetrating tissue, such as finger tip, blood sample outflow has been waited
Afterwards, the acquisition that hemostix 50 carries out blood sample is taken out, applies blood sample to sample application well 104, at this point, solution storage device
30 is in the unlocked state, waits after applying sample, pushes solution storage device 30 from first movement to the second position, due to thorn
Broken element 40 is fixed, and with the second position that is pushed to of solution storage device 30, puncturing elements puncture sealing film 31, and
It punctures after head enters solution cavity 303, liquid or solution is forced to be entered in channel by the one end open 403 in channel, and
It is flowed into sample applying zone by another end opening 406, the solution being flowed into applying zone flows through sample application well 10
Corresponding sample applying zone, handles sample disposed thereon, to complete to test or chemically examine.
Above method is to be directed to blood sample, when not being blood sample, it may not be necessary to puncture device, and directly use
Hemostix carries out taking for sample, such as saliva, excrement etc. can such as be carried out above for the explanation of sample with hemostix
It takes.
In the case where lacking any element specifically disclosed herein, limitation, may be implemented illustrated and described herein
Utility model.Used terms and expressions method is used as the term of explanation and unrestricted, and is not intended in these terms
Any equivalent of shown and described feature or part thereof with exclusion in the use of representation, and should be realized that various change
Type is all feasible in the scope of the utility model.It is therefore to be understood that although passing through various embodiments and optional feature
The utility model is specifically disclosed, but the modifications and variations of concept as described herein can be by those of ordinary skill in the art institute
Using, and think that these modifications and variations are fallen within the scope of the utility model of the appended claims restriction.
It is described herein or record article, patent, patent application and every other document and can electronically obtain
The content of information include herein by reference, just as each individual publication by specific and single in full to a certain extent
Solely point out by reference.Applicant retains from any of any this article, patent, patent application or other documents
And all material and information are incorporated into the right in the application.
Claims (10)
1. a kind of detection device with hemostix, which is characterized in that the device includes hemostix, and the hemostix is inserted into
To inserting in the hole for detection device, wherein the hemostix includes a projecting block, which is located at the cavity of detection device
In and close to test chamber inner wall on.
2. detection device according to claim 1, which is characterized in that the hemostix includes blood sampling head.
3. detection device according to claim 1, which is characterized in that the hemostix is " L " shape.
4. detection device according to claim 1, which is characterized in that the projecting block be located at " L " shape it is long-armed on.
5. detection device according to claim 1, which is characterized in that the insertion hole is rectangle, and hemostix is pipe
Shape structure, rectangular height are corresponding with the diameter of the tubular structure of hemostix.
6. detection device according to claim 5, which is characterized in that the projecting block is rectangular parallelepiped structure, and is adopted
The tubular structure of blood device is in approximately the same plane.
7. detection device according to claim 3, which is characterized in that the long-armed of hemostix of described " L " shape is located at
In detection device, galianconism is located at outside detection device.
8. detection device according to claim 2, which is characterized in that the detection device further includes solution storage device,
In solution storage device upper including lockhole, the blood sampling head is located in lockhole, to which fixed solution reservoir is in detection device
On position.
9. a kind of detection device with hemostix, which is characterized in that the device includes hemostix, and the hemostix is inserted into
To inserting in the hole for detection device, wherein the detection device further includes solution storage device, includes upper in solution storage device
Lockhole, the hemostix include blood sampling head, and the blood sampling head is located in lockhole, to which fixed solution reservoir is filled in detection
The position set.
10. detection device according to claim 9, which is characterized in that the hemostix includes a projecting block, described
Projecting block is rectangular parallelepiped structure, and the tubular structure of hemostix is in approximately the same plane.
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| CN201721188212.2U CN207703867U (en) | 2017-09-15 | 2017-09-15 | A kind of detection device with hemostix |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107907673A (en) * | 2017-10-12 | 2018-04-13 | 杭州博拓生物科技股份有限公司 | A kind of method of analyte in detection sample |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107907673A (en) * | 2017-10-12 | 2018-04-13 | 杭州博拓生物科技股份有限公司 | A kind of method of analyte in detection sample |
| CN107907673B (en) * | 2017-10-12 | 2020-04-10 | 杭州博拓生物科技股份有限公司 | Method for detecting analyzed substance in sample |
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