CN207694868U - A kind of test tube fixing device for sonicator - Google Patents
A kind of test tube fixing device for sonicator Download PDFInfo
- Publication number
- CN207694868U CN207694868U CN201721793708.2U CN201721793708U CN207694868U CN 207694868 U CN207694868 U CN 207694868U CN 201721793708 U CN201721793708 U CN 201721793708U CN 207694868 U CN207694868 U CN 207694868U
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- China
- Prior art keywords
- test tube
- fixture block
- fixed cylinder
- fixing device
- slot
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000012360 testing method Methods 0.000 title claims abstract description 123
- 239000011229 interlayer Substances 0.000 claims abstract description 8
- 239000012774 insulation material Substances 0.000 claims abstract description 6
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 26
- 210000003734 kidney Anatomy 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 8
- 125000004122 cyclic group Chemical group 0.000 claims description 3
- 239000005457 ice water Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 238000000527 sonication Methods 0.000 description 2
- 230000001464 adherent effect Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011490 mineral wool Substances 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000002525 ultrasonication Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
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- Sampling And Sample Adjustment (AREA)
Abstract
The utility model is related to a kind of test tube fixing devices for sonicator, belong to cell breaking plant technical field, test tube is difficult to fixed, rack for test tube interchangeability difference technical problem during solving the cell breaking plants use such as Ultrasonic Cell Disruptor in the prior art, and solution is：It includes test tube fixing device, test tube pallet and test tube fixed cylinder, the side wall of test tube fixed cylinder is provided with interlayer, thermal insulation material is filled in interlayer, one group of rotary disk limitation slot is symmetrically arranged on the outside of test tube fixed cylinder, the upper end of the test tube fixed cylinder is set as open end, the outer wall of open end is provided with screw thread, and fixing device is threadedly coupled with the open end of test tube fixed cylinder, and test tube pallet is installed on the inside of test tube fixed cylinder.The utility model perseverance cryogenic property is good, and test tube fixing device interchangeability is strong, and test tube fixing device and test tube pallet cooperation support action are good, and test tube position in test tube fixing device is stablized.
Description
Technical field
The utility model belongs to cell breaking plant technical field, and in particular to a kind of test tube for sonicator
Fixing device.
Background technology
Electric energy is exactly converted to acoustic energy by sonication instrument by energy converter, and the cavitation based on ultrasonic wave in a liquid is made
With electric flux is generated high intensity shearing force by energy converter by amplitude transformer in tool heads overhead-liquid, forms the alternation of high frequency
Hydraulic pressure is strong, and expandable cavity, explosion is made to smash cell.Sonication instrument for a variety of animal and plant cells, virocyte it is broken,
Prepare liposome or nanoparticle etc., be widely used in biochemistry, microbiology, pharmaceutical chemistry, pharmacy, surface chemistry,
The experiment and research work such as extraction of zoology and production of vaccine, surface antigen.
But the cell breaking plants such as Ultrasonic Cell Disruptor used in the prior art have the following defects：
1., using when Ultrasonic Cell Disruptor without heat sink.When being ultrasonically treated, the molecular motion in formulation samples generally can
Cause temperature rise, especially faster, this will influence the stability of formulation samples to temperature rise in the case where volume is smaller.It passes
System method is that test tube is put into ice-water bath beaker again after being ultrasonically treated, and a large amount of thermal energy generated when being ultrasonically treated will cause drug
Stability is destroyed, and using effect is undesirable.
2., using when Ultrasonic Cell Disruptor without test tube fixing device.Generally require ultrasonic probe placed in the middle when being ultrasonically treated, no
It is adherent, and fixed into liquid depth, therefore it is more demanding to the degree of stability of test tube.Conventional method is to hold or be placed on test tube
It is hand-held to be easy to cause shaking on frame, so that ultrasonic probe is encountered tube wall or Level Change, influences crushing efficiency.
3., traditional rack for test tube specification it is consistent, specification test tube of the same race, therefore the need when test tube specification changes can only be placed per hole
Other specification rack for test tubes are changed to fix test tube, conventional efficient will be influenced.
Utility model content
In order to overcome the shortcomings of the prior art, solves the cell breaking plants such as Ultrasonic Cell Disruptor in the prior art and use
Test tube is difficult to fixed, rack for test tube interchangeability difference technical problem in the process, and the utility model provides a kind of for ultrasonic disruption
The test tube fixing device of instrument.
The utility model is achieved by the following technical programs：
A kind of test tube fixing device for sonicator, it includes test tube fixing device, test tube pallet and test tube
Fixed cylinder, wherein：
The side wall of test tube fixed cylinder is provided with interlayer, thermal insulation material is filled in interlayer, along the diameter side of test tube fixed cylinder
To one group of rotary disk limitation slot is symmetrically arranged on the outside of test tube fixed cylinder, the lower surface of the rotary disk limitation slot is set as upward
The cambered surface of bending；The upper end of the test tube fixed cylinder is set as open end, and the outer wall of open end is provided with screw thread, fixing device
It is threadedly coupled with the open end of test tube fixed cylinder, test tube pallet is installed on the inside of test tube fixed cylinder；
The fixing device includes the turntable from top to bottom set gradually, fixture block and fixture block pedestal, turntable and fixture block pedestal
It is disposed as annular shape, several axis pins are along the circumferential direction evenly arranged in the upper surface of fixture block pedestal；The lower end of fixture block one end
It is provided with boss between face and fixture block pedestal, boss and fixture block are provided with pin shaft hole, the other end of fixture block is set as arc
Closed angle end is provided with arc kidney slot in the middle part of fixture block, and the pin shaft hole correspondence on several pieces of fixture blocks is installed on axis pin, every piece of card
Block rotates rotating around axis pin；The turntable rotates relative to fixture block pedestal, lower face and the fixture block bottom of turntable
Arc waist hole position corresponding position is provided with several limit shafts between the upper surface of seat, limit shaft is respectively in corresponding curved waist
Shape is slided in hole；
It is provided with saddle in the middle part of test tube pallet lower surface, support is provided between saddle and the bottom surface of test tube fixed cylinder
Disk spring is provided with pyramidal pits in the middle part of test tube tray upper surface, in pyramidal pits both sides along the diametric(al) of test tube pallet
It is symmetrically arranged with sliding slot, sliding block is provided in sliding slot, the lower surface of sliding block is set as matching with the lower surface of rotary disk limitation slot
Cambered surface, connected by sliding block spring between sliding block and the center portion of test tube pallet, the sliding block spring is in compressive state, sliding block
Spring drives sliding block from being slid into sliding slot in rotary disk limitation slot.
Further, when the turntable driving limit shaft slides into arc kidney slot close to axis pin side, several pieces of fixture blocks
Arc closed angle end be closed, the diameter of the polygon of the intrados composition of several pieces of fixture blocks is equal to the diameter of test tube；The turntable
When driving limit shaft slides into arc kidney slot far from axis pin side, the arc closed angle end of several pieces of fixture blocks opens, several pieces of cards
The diameter of the polygon of the intrados composition of block is not less than the diameter of cyclic annular turntable and fixture block pedestal inner headed face.
Further, the axis direction according to the model of test tube along test tube fixed cylinder is disposed with several groups from top to bottom
Rotary disk limitation slot.
Further, the fixture block is along the circumferential direction evenly arranged with six pieces along fixture block base upper surface.
Further, when fixture block closed state, on the medial surface of fixture block arc closed angle end with the contact of test tube outer wall
Cushion block is provided between face.
The utility model has the advantages that compared with prior art：
1, permanent cryogenic property is good.Since molecular motion causes temperature to increase in ultrasonication, easily make the products such as nucleic acid point
Solution, the present apparatus maintain permanent low temperature by thermal insulation material, and the fixture block in the test tube fixing device of upper end is effectively kept away with test tube close contact
Exempt from ice water to contact with the external world, keeps permanent low temperature.
2, fixed supporting function.The fixture block of upper end effectively secures test tube, and the pallet of lower end plays supporting function, back taper
Pedestal effectively prevent the swing of test tube.
3, it is suitable for Multiple Type.With multiple gears, the test tube of different model is adapted to, the back taper recess of pallet is set
Meter, which can change little height, to be adapted to, and has universal usability.
Description of the drawings
Fig. 1 is the utility model entirety main view schematic cross-sectional view.
Fig. 2 is that test tube fixing device removes present invention looks up structural representation after fixture block pedestal to fixture block in the closure state.
Fig. 3 is that test tube fixing device removes present invention looks up structural representation after fixture block pedestal when fixture block is in open configuration.
Fig. 4 is the main structure diagram of fixture block in Fig. 2 or Fig. 3.
Fig. 5 is the right side structural representation of fixture block in Fig. 4.
Fig. 6 is the main structure diagram of turntable.
Fig. 7 is the present invention looks up structural representation of Fig. 6 turntables.
In figure, 1 is turntable, and 11 be limit shaft, and 21 be boss, and 22 be fixture block, and 23 be arc kidney slot, and 24 be fixture block bottom
Seat, 25 be axis pin, and 3 be test tube fixed cylinder, and 31 be rotary disk limitation slot, and 41 be test tube pallet, and 42 be sliding block, and 43 be saddle, and 44 are
Tray spring, 45 be sliding slot, and 46 be sliding block spring.
Specific implementation mode
The utility model is described in further detail with reference to the accompanying drawings and examples.
A kind of test tube fixing device for sonicator as shown in Figures 1 to 7, it includes that test tube fixes dress
It sets, test tube pallet 41 and test tube fixed cylinder 3, wherein：
The side wall of test tube fixed cylinder 3 is provided with interlayer, thermal insulation material is filled in interlayer, along the diameter of test tube fixed cylinder 3
Direction is symmetrically arranged with one group of rotary disk limitation slot 31 to the outside of test tube fixed cylinder 3, and the lower surface of the rotary disk limitation slot 31 is set
It is set to the cambered surface being bent upwards；The upper end of the test tube fixed cylinder 3 is set as open end, and the outer wall of open end is provided with spiral shell
Line, fixing device are threadedly coupled with the open end of test tube fixed cylinder 3, and test tube pallet 41 is installed on the inside of test tube fixed cylinder 3；
The fixing device includes the turntable 1 from top to bottom set gradually, fixture block 22 and fixture block pedestal 24, turntable 1 and card
Block pedestal 24 is disposed as annular shape, and several axis pins 25 are along the circumferential direction evenly arranged in the upper surface of fixture block pedestal 24；Card
It is provided with boss 21 between the lower face and fixture block pedestal 24 of 22 one end of block, boss 21 and fixture block 22 are provided with pin shaft hole,
The other end of fixture block 22 is set as arc closed angle end, and the middle part of fixture block 22 is provided with arc kidney slot 23, on several pieces of fixture blocks 22
Pin shaft hole correspondence be installed on axis pin 25, every piece of fixture block 22 rotates rotating around axis pin 25；The turntable 1 is relative to card
Block pedestal 24 rotates, between the lower face and the upper surface of fixture block pedestal 24 of turntable 1 with 23 position pair of arc kidney slot
Should place be provided with several limit shafts 11, limit shaft 11 slides in corresponding arc kidney slot 23 respectively；
It is provided with saddle 43 in the middle part of 41 lower surface of test tube pallet, between saddle 43 and the bottom surface of test tube fixed cylinder 3
It is provided with tray spring 44, test tube pallet is provided with pyramidal pits in the middle part of 41 upper surface, in pyramidal pits both sides along test tube support
The diametric(al) of disk 41 is symmetrically arranged with sliding slot 45, and sliding block 42 is provided in sliding slot 45, and the lower surface of sliding block 42 is set as and turns
The matched cambered surface in lower surface of disk limiting slot 31, is connected between sliding block 42 and the center portion of test tube pallet 41 by sliding block spring 46
It connects, the sliding block spring 46 is in compressive state, and sliding block spring 46 drives sliding block 42 to slide into rotary disk limitation slot from sliding slot 45
In 31.
Further, it is several when the turntable 1 drives limit shaft 11 to slide into arc kidney slot 23 close to 25 side of axis pin
The arc closed angle end of block fixture block 22 is closed, and the diameter of the polygon of the intrados composition of several pieces of fixture blocks 22 is equal to the straight of test tube
Diameter；When the turntable 1 drives limit shaft 11 to slide into arc kidney slot 23 far from 25 side of axis pin, the arc of several pieces of fixture blocks 22
Closed angle end opens, and the diameter of the polygon of the intrados composition of several pieces of fixture blocks 22 is not less than cyclic annular turntable 22 and fixture block pedestal 24
The diameter of inner headed face.
Further, it is disposed with from top to bottom along the axis direction of test tube fixed cylinder 3 according to the model of test tube several
Group rotary disk limitation slot 31.
Further, the fixture block 22 is along the circumferential direction evenly arranged with six pieces along 24 upper surface of fixture block pedestal.
Further, when 22 closed state of fixture block, on the medial surface of 22 arc closed angle end of fixture block with test tube outer wall
Cushion block is provided between contact surface.
The utility model use process is as follows：
In figure, 1 is turntable, and 11 be limit shaft, and 21 be boss, and 22 be fixture block, and 23 be arc kidney slot, and 24 be fixture block bottom
Seat, 25 be axis pin, and 3 be test tube fixed cylinder, and 31 be rotary disk limitation slot, and 41 be test tube pallet, and 42 be sliding block, and 43 be saddle, and 44 are
Tray spring, 45 be sliding slot, and 46 be sliding block spring.
Rotary turnplate 1, limit shaft 11 make 22 outward turning of fixture block, and the arc closed angle end of fixture block 22 is in open configuration, model compared with
Small test tube is put into from cricoid turntable 1 and fixture block pedestal 24 in test tube fixed cylinder 3, and the bottom of test tube can touch test tube pallet
In 41 pyramidal pits, pyramidal pits can fix test tube bottom, prevent test tube from tilting.After test tube pallet 41 is touched in test tube bottom
It presses at first group of 31 position of rotary disk limitation slot, sliding block 42 is popped up by sliding block spring 46, and sliding block 42 is sprung into first group of turntable
In limiting slot 31, the height of test tube is fixed.
Turntable 1 is reversely rotated, fixture block 22 rotates inward, and the arc closed angle end of fixture block 22 is in closed state to clamp examination
Pipe.
It is essentially identical with above-mentioned steps when using the larger test tube of type instead.Test tube is firmly pushed, test tube bottom pushes examination
Conduit saddle disk 41, sliding block 42 continue to push test tube pallet 41, due to 31 bottom of rotary disk limitation slot in first group of rotary disk limitation slot 31
For the cambered surface being bent upwards, 42 bottom surface of sliding block is similarly cambered surface, therefore sliding block 42 can continue directly to press to second group of turntable limit
Then position slot 31 reversely rotates turntable 1, fixture block 22 is rotated inward to fix test tube.
After test tube takes out, slight left-right rotation test tube pallet 41 revolves sliding block 42 from second group of rotary disk limitation slot 31
Go out, sliding block 42 is pressed into sliding slot 45.Tray spring 44, which affranchises, state and to be restored test tube pallet 41 to initial position.
Turntable 1 is finally reversely rotated, the rotation of fixture block 22 reduces open circles to closure.Freely it can place and incline inside the present apparatus
Ice water, shell are thermal insulation material mineral wool, and isoperibol and ice-water bath are provided for test tube.
Above description is only a specific implementation of the present invention, but the scope of protection of the utility model is not limited to
It is any to be familiar with those skilled in the art within the technical scope disclosed by the utility model in this, the variation that can be readily occurred in
Or replace, it should be covered within the scope of the utility model.Therefore, the scope of protection of the utility model should be with the power
Subject to the protection domain that profit requires.
Claims (5)
1. a kind of test tube fixing device for sonicator, it includes test tube fixing device, test tube pallet（41）And examination
Pipe fixed cylinder（3）, it is characterised in that：
Test tube fixed cylinder（3）Side wall be provided with interlayer, thermal insulation material is filled in interlayer, along test tube fixed cylinder（3）Diameter
Direction is to test tube fixed cylinder（3）Outside be symmetrically arranged with one group of rotary disk limitation slot（31）, the rotary disk limitation slot（31）Under
Surface is set as the cambered surface being bent upwards；The test tube fixed cylinder（3）Upper end be set as open end, the outer wall of open end is set
It is equipped with screw thread, fixing device and test tube fixed cylinder（3）Open end be threadedly coupled, test tube pallet（41）It is installed on test tube fixed cylinder
（3）Inside；
The fixing device includes the turntable from top to bottom set gradually（1）, fixture block（22）With fixture block pedestal（24）, turntable（1）
With fixture block pedestal（24）It is disposed as annular shape, in fixture block pedestal（24）Upper surface be along the circumferential direction evenly arranged with several pins
Axis（25）；Fixture block（22）The lower face of one end and fixture block pedestal（24）Between be provided with boss（21）, run through boss（21）With card
Block（22）It is provided with pin shaft hole, fixture block（22）The other end be set as arc closed angle end, fixture block（22）Middle part be provided with arc
Kidney slot（23）, several pieces of fixture blocks（22）On pin shaft hole correspondence be installed on axis pin（25）On, every piece of fixture block（22）Rotating around pin
Axis（25）It rotates；The turntable（1）Relative to fixture block pedestal（24）It rotates, turntable（1）Lower face and card
Block pedestal（24）Upper surface between with arc kidney slot（23）Position corresponding position is provided with several limit shafts（11）, limit shaft
（11）Respectively in corresponding arc kidney slot（23）Middle sliding；
The test tube pallet（41）Saddle is provided in the middle part of lower surface（43）, saddle（43）With test tube fixed cylinder（3）Bottom surface
Between be provided with tray spring（44）, test tube pallet（41）Pyramidal pits are provided in the middle part of upper surface, in pyramidal pits both sides
Along test tube pallet（41）Diametric(al) be symmetrically arranged with sliding slot（45）, sliding slot（45）Inside it is provided with sliding block（42）, sliding block（42）
Lower surface be set as and rotary disk limitation slot（31）The matched cambered surface in lower surface, sliding block（42）With test tube pallet（41）The heart
Pass through sliding block spring between portion（46）Connection, the sliding block spring（46）In compressive state, sliding block spring（46）Drive sliding block
（42）From sliding slot（45）In slide into rotary disk limitation slot（31）In.
2. a kind of test tube fixing device for sonicator according to claim 1, it is characterised in that：Described turn
Disk（1）Drive limit shaft（11）Slide into arc kidney slot（23）Close to axis pin（25）When side, several pieces of fixture blocks（22）Arc
Shape closed angle end is closed, several pieces of fixture blocks（22）Intrados composition polygon diameter be equal to test tube diameter；The turntable
（1）Drive limit shaft（11）Slide into arc kidney slot（23）Far from axis pin（25）When side, several pieces of fixture blocks（22）Arc
Closed angle end opens, several pieces of fixture blocks（22）The diameter of polygon of intrados composition be not less than cyclic annular turntable and fixture block pedestal
（24）The diameter of inner headed face.
3. a kind of test tube fixing device for sonicator according to claim 1, it is characterised in that：According to examination
The model of pipe is along test tube fixed cylinder（3）Axis direction be disposed with several groups rotary disk limitation slot from top to bottom（31）.
4. a kind of test tube fixing device for sonicator according to claim 1, it is characterised in that：The card
Block（22）Along fixture block pedestal（24）Upper surface is along the circumferential direction evenly arranged with six pieces.
5. a kind of test tube fixing device for sonicator according to claim 1, it is characterised in that：Work as fixture block
（22）When closed state, in fixture block（22）Pad is provided on the medial surface of arc closed angle end between the contact surface of test tube outer wall
Block.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721793708.2U CN207694868U (en) | 2017-12-20 | 2017-12-20 | A kind of test tube fixing device for sonicator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721793708.2U CN207694868U (en) | 2017-12-20 | 2017-12-20 | A kind of test tube fixing device for sonicator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207694868U true CN207694868U (en) | 2018-08-07 |
Family
ID=63027442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721793708.2U Active CN207694868U (en) | 2017-12-20 | 2017-12-20 | A kind of test tube fixing device for sonicator |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207694868U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107983437A (en) * | 2017-12-20 | 2018-05-04 | 黄泽浩 | Test tube fixing device for sonicator |
| CN112964811A (en) * | 2021-02-05 | 2021-06-15 | 杨德毅 | Fixed nitrogen blowing instrument |
-
2017
- 2017-12-20 CN CN201721793708.2U patent/CN207694868U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107983437A (en) * | 2017-12-20 | 2018-05-04 | 黄泽浩 | Test tube fixing device for sonicator |
| CN112964811A (en) * | 2021-02-05 | 2021-06-15 | 杨德毅 | Fixed nitrogen blowing instrument |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20200511 Address after: Room 103, floor 1, innovation and entrepreneurship training center, Shanxi Medical University, No. 1258, Xinjian North Road, Yuci District, Jinzhong City, Shanxi Province Patentee after: Shanxi Tangshu Pharmaceutical Technology Co., Ltd Address before: 030001 39, 24 unit two, crescent building, 2 Qiaotou street, Yingze District, Taiyuan, Shanxi. Co-patentee before: Zhang Shengxiao Patentee before: Huang Zehao |