CN207680092U - A kind of chromatographic column - Google Patents
A kind of chromatographic column Download PDFInfo
- Publication number
- CN207680092U CN207680092U CN201721515110.7U CN201721515110U CN207680092U CN 207680092 U CN207680092 U CN 207680092U CN 201721515110 U CN201721515110 U CN 201721515110U CN 207680092 U CN207680092 U CN 207680092U
- Authority
- CN
- China
- Prior art keywords
- cylinder
- column
- wall
- bearing plate
- diversion trench
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000007788 liquid Substances 0.000 claims abstract description 14
- 230000002787 reinforcement Effects 0.000 claims abstract description 5
- 238000003756 stirring Methods 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims description 3
- 238000001802 infusion Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000000126 substance Substances 0.000 description 3
- 238000000926 separation method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 238000007445 Chromatographic isolation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
Landscapes
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
The utility model is related to a kind of chromatographic columns, including column cap, cylinder and column bottom, and first flange group is equipped between column cap and cylinder, and second flange group is equipped between column bottom and cylinder：The lower face of column cap is hemisphere face, and column cap is equipped with blender；Cylinder has the inner wall of downward frustoconical, the lower end of inner wall is equipped with colored orifice plate, the side wall of cylinder is provided along its length multilayer force-bearing plate, is equipped with buffer board between adjacent force-bearing plate, spaced buffer stopper and reinforcement block are equipped between outermost force-bearing plate and cylinder；Column bottom includes diversion trench, and the center of diversion trench is equipped with liquid outlet, and diversion trench includes 10 annular grooves and 8 using liquid outlet as the bar-shaped trough of the radial arrangement in the center of circle.The utility model improves the stability, uniformity of sample-adding and discharge；Simple in structure but secured, operation and dismounting facilitate, cylinder are avoided to rupture liquid splash, improve practicability.
Description
Technical field
The utility model is related to a kind of separator of biological chemical field more particularly to a kind of chromatographic columns.
Background technology
Chromatographic isolation is to purify a kind of highest method of means efficiency in pharmaceutical industry, biological chemical field at present, is
One of the important means of the separation of natural products and the preparation of other high purity substances, application is more and more extensive.Chromatographic column is system
The key equipment of various liquid chromatogram separation, chromatographic column for laboratory diameter is often all smaller, the liquid being added in gel surface
Phase sample will soon radial diffusion, for the chromatographic column applied in industrial production, in order to improve yield, it chromatographs what column diameter was done
Very big, improve the continuity, uniformity, stability of sample-adding seems extremely important for improving separative efficiency and product quality.
Utility model content
The purpose of this utility model is to be directed to above-mentioned present situation, provides a kind of chromatographic column.
The technical solution adopted in the utility model：A kind of chromatographic column, including column cap, cylinder and column bottom, the column cap and institute
The upper end-face edge for stating cylinder is equipped with mutually matched first flange group, and the lower edge of the column bottom and the cylinder is equipped with mutual
The second flange group of cooperation：Wherein：
The column cap has the hemispheric lower face being recessed upwards, and the column cap includes inlet, fluid infusion, venthole
With the blender for cleaning the inboard wall of cylinder with water；
The top of the cylinder has the inner wall of downward frustoconical, circumferential inwardly extending one end of lower edge of inner wall
Distance forms card slot, and the card slot has been removably installed colored orifice plate, and the bottom of the cylinder is equipped with sieve plate, the side of the cylinder
Wall is provided along its length multilayer force-bearing plate, and buffer board, the outermost force-bearing plate are equipped between the adjacent force-bearing plate
Spaced buffer stopper and reinforcement block are equipped between the cylinder；
The column bottom includes diversion trench, and the center of the diversion trench is equipped with liquid outlet, and the diversion trench includes 10 annulars
Slot and 8 are using the liquid outlet as the bar-shaped trough of the radial arrangement in the center of circle.
The utility model has the beneficial effects that：Improve the stability, uniformity of sample-adding and discharge；It is simple in structure but secured,
Operation and dismounting facilitate, cylinder are avoided to rupture liquid splash, improve practicability.
Description of the drawings
Involved attached drawing is simply introduced in being described to the embodiment of the present invention, in order to in the embodiment of the present invention
Technical solution become apparent from, completely illustrated, attached drawing below is only for some embodiments of the present invention, not limiting
The system present invention, under the premise of without other creative works, it is clear that other accompanying drawings can be obtained according to these attached drawings.
Fig. 1 is the structural schematic diagram of the chromatographic column of the utility model；
Fig. 2 is the enlarged drawing at A in Fig. 1.
Specific implementation mode
The principles of the present invention and feature are described below in conjunction with attached drawing, example is served only for explaining this practicality
It is novel, it is not intended to limit the scope of the utility model.
As shown in Figure 1, a kind of chromatographic column provided by the utility model, including column cap 1, cylinder 2 and column bottom 3.Column cap 1 and column
The upper end-face edge of body 2 is equipped with mutually matched first flange group 4, and the lower edge of column bottom 3 and cylinder 2 is equipped with mutually matched the
Two flange groups 5, three seal against each other connection.
With continued reference to Fig. 1, column cap 1 is equipped with inlet 10, fluid infusion 11, venthole 12 and blender 13, wherein feed liquor
Mouth 10 and venthole 12 are connected to the lower face of column cap 1 outside column cap 1, and blender 13 includes being vertically provided at stirring in cylinder 2
The mixing page 131 mixed bar 130 and be arranged at intervals on stirring rod 130, the electricity that the drive connection of stirring rod 130 is arranged outside cylinder 2
Machine, mixing page 131 can clean the inner wall of cylinder 1 with water.Column cap 1 has the hemispheric lower face being recessed upwards, the top tool of cylinder 2
The circumferential inwardly extending one end distance of lower edge of the inner wall of the frustoconical of oriented lower recess, inner wall forms card slot 20, card slot
20 have been removably installed colored orifice plate 201.Liquid enters from inlet 10, and a part flows directly into cavity, and small part can be along
The inner wall of cavity flows to colored orifice plate 201, and the liquid of entrance is made more uniformly to reach inside cylinder 2.
Preferably, it is also connected with a deceleration between the output end and blender 13 of the motor of the control connection of blender 13
Device.
The bottom end of cylinder 2 is equipped with sieve plate 202, and the side wall of cylinder 2 is provided along its length multilayer force-bearing plate 21, adjacent resistance to
Buffer board 22 is equipped between power plate 21, the setting of the force-bearing plate 21 of innermost layer can improve the pressure-resistant performance of cylinder 2, to avoid
Pressure is excessive when filling column, and cylinder 2 ruptures.
As shown in Fig. 2, being equipped with spaced buffer stopper 23 between the outermost force-bearing plate 21 and the side wall of cylinder 2
Setting with reinforcement block 24, buffer stopper 23 prevents the force-bearing plate 21 of internal layer from damaging cylinder 2 because pressure crosses Major disruptionL, adds
Strong block 24 can do the firmness for improving 2 lateral wall of cylinder, and cylinder 2 is avoided to be ruptured because of external force collision.
Preferably, the material of buffer board 22 and buffer stopper 23 is sponge.Reinforcement block 24 is wooden unit.
Preferably, the draw ratio of cylinder 2 is more than 4：1, larger draw ratio elongated significantly in extracting solution target product and
Gas componant is in the path of chromatographic column, and due to the movement speed of target product and gas componant on chromatographic column in extracting solution
It is different so that the distance of target product and other compositions on chromatographic column widens, to realize Fractional Collections.
Further, column bottom 3 includes diversion trench 31, and the center of diversion trench 31 is equipped with liquid outlet 32.Wherein, diversion trench 31 includes
10 annular grooves and 8 are with the bar-shaped trough that liquid outlet 32 is the radial arrangement in the center of circle.
Further, 4 universal wheels 32 are equipped with along the edge at column bottom 3 is circumferentially-spaced.
The preferred embodiment that these are only the utility model, is not intended to limit the utility model, all in the utility model
Spirit and principle within, any modification, equivalent replacement, improvement and so on should be included in the protection model of the utility model
Within enclosing.
Claims (4)
1. a kind of chromatographic column, which is characterized in that including column cap, cylinder and column bottom, the upper end-face edge of the column cap and the cylinder
Equipped with mutually matched first flange group, the lower edge of the column bottom and the cylinder is equipped with mutually matched second flange
Group：Wherein：
The column cap has the hemispheric lower face that is recessed upwards, and the column cap includes inlet, fluid infusion, venthole and clear
Brush the blender of the inboard wall of cylinder；
The top of the cylinder has the inner wall to the frustoconical of lower recess, circumferential inwardly extending one end of lower edge of inner wall
Distance forms card slot, and the card slot has been removably installed colored orifice plate, and the bottom of the cylinder is equipped with sieve plate, the side of the cylinder
Wall is provided along its length multilayer force-bearing plate, and buffer board, the outermost force-bearing plate are equipped between the adjacent force-bearing plate
Spaced buffer stopper and reinforcement block are equipped between the cylinder；
The column bottom includes diversion trench, and the center of the diversion trench is equipped with liquid outlet, and the diversion trench includes 10 annular grooves and 8
It is a using the liquid outlet as the bar-shaped trough of the radial arrangement in the center of circle.
2. a kind of chromatographic column according to claim 1, which is characterized in that the blender includes being vertically provided at the column
Internal stirring rod and the mixing page being arranged at intervals on the stirring rod, the top of the stirring rod, which is sequentially connected, to be arranged in institute
State the motor outside cylinder.
3. a kind of chromatographic column according to claim 2, which is characterized in that the draw ratio of the cylinder is more than 4：1.
4. a kind of chromatographic column according to claim 3, which is characterized in that the edge along the column bottom circumferentially-spaced is equipped with 4
A universal wheel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721515110.7U CN207680092U (en) | 2017-11-14 | 2017-11-14 | A kind of chromatographic column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721515110.7U CN207680092U (en) | 2017-11-14 | 2017-11-14 | A kind of chromatographic column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207680092U true CN207680092U (en) | 2018-08-03 |
Family
ID=62989497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721515110.7U Expired - Fee Related CN207680092U (en) | 2017-11-14 | 2017-11-14 | A kind of chromatographic column |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207680092U (en) |
-
2017
- 2017-11-14 CN CN201721515110.7U patent/CN207680092U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180803 |